LOCUS       NZ_JAKVIE010000005     20870 bp    DNA     linear   CON 23-JAN-2024
DEFINITION  Streptococcus pasteurianus strain D17293137
            D17293137_S20_contig_5_consensus, whole genome shotgun sequence.
ACCESSION   NZ_JAKVIE010000005
VERSION     NZ_JAKVIE010000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pasteurianus
  ORGANISM  Streptococcus pasteurianus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 148755)
  AUTHORS   Christensen,J., Jensen,C., Dargis,R., Nielsen,X., Pries- Heje,M.,
            Wiingaard,C., Ihlemann,N., Gill,S., Bruun,N., Elming,H., Povlsen,J.,
            Madsen,T., Jensen,K., Fuursted,K., Ostergaard,L., Christiansen,U.,
            Rosenvinge,F., Helweg-Larsen,J., Fosbol,E., Kober,L.,
            Torp-Pedersen,C., Tonder,N., Moser,C., Iversen,K. and Bundgaard,H.
  TITLE     Genomic identification of streptococcal strains and relation to
            clinical characteristics. A substudy to The Partial Oral Treatment
            of Endocarditis (POET) Trial
  JOURNAL   Med Res Arch 10 (9) (2022) In press
  REMARK    DOI: 10.18103/mra.v10i9.3037
REFERENCE   2  (bases 1 to 148755)
  AUTHORS   Christensen,J.J.E., Jensen,C.S., Nielsen,X.C. and Dargis,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2022) Department of Clinical Microbiology, Region
            Zealand, Ingemannsvej 46, Slagelse 4200, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 72.66x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/23/2024 02:09:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,313
            CDSs (total)                      :: 2,260
            Genes (coding)                    :: 2,168
            CDSs (with protein)               :: 2,168
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 38 of 92
            Pseudo Genes (incomplete)         :: 58 of 92
            Pseudo Genes (internal stop)      :: 34 of 92
            Pseudo Genes (multiple problems)  :: 30 of 92
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:47:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 98779
            Orig. end                         :: 119649
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAKVIE010000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20870
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20870
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20870
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10870](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10870)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            785..985
                     /locus_tag="MK857_RS02840"
                     /old_locus_tag="MK857_02830"
     CDS             785..985
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006532374.1"
                     /locus_tag="MK857_RS02840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02830"
                     /product="hypothetical protein"
                     /protein_id="WP_117575035.1"
                     /transl_table=11
                     /translation="MESETRPMEIVCYDLDCHCNRRREWIKVNGEWHPIEYSVDDPNDP
                     PMSEEEKQKLADIILEFTAEK"
     gene            1038..1673
                     /locus_tag="MK857_RS02845"
                     /old_locus_tag="MK857_02835"
     CDS             1038..1673
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024380.4"
                     /locus_tag="MK857_RS02845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02835"
                     /product="DUF3862 domain-containing protein"
                     /protein_id="WP_268700107.1"
                     /transl_table=11
                     /translation="MKKIGLLGLTLLSVATLSACSSSKTDNKNTSSSSSVEQTTSSTSA
                     EETKKAVRSVYDSVVVGDLMNNGEGGTTKDTVINAYGNPASTSTTSLNGMNVEQVTWIG
                     NGNATGITISIQFINNNATSKMISGFQFSRDSKIGLTEFNNLATGTSYADVVNTLGEPD
                     TTSESLISGSKSVTANWITGIKGNVGANFVLQFTNDSLTSKSQSGLTD"
     gene            1684..2709
                     /locus_tag="MK857_RS02850"
                     /old_locus_tag="MK857_02840"
     CDS             1684..2709
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MK857_RS02850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MK857_02840"
                     /product="hypothetical protein"
                     /protein_id="WP_268700108.1"
                     /transl_table=11
                     /translation="MKRDLKELIQELLEHIDNNPLTDEQIEKIEKWKNGLRRIGKKGRS
                     TVKEIIYLDTVFVNSILAQMNKGLVTKLVNEDMETDSSSDSSTESTTSSGSMGINKIIA
                     ANTTHSELESETSQVVFSKSNKDLIETAIDDYSLDLLLNDLKANNFIINQNYGDGDVIQ
                     IEGELTTYDFKQLANASSLEEIEFLLPDYDEYKKNAAEYNKIKNKNIPRADELKEYLSG
                     NGWQNFDNLKNMSSYLDKLLPNTSIIKVNDALCIVSDKLLRVQKSQLSFMQLGKRKVKM
                     LGICSSTIDERVPSNFDSMANSQYLIRYAPTTIINIMLGSFNLINGGDHIVRPIAIYFE
                     D"
     gene            complement(2694..2885)
                     /locus_tag="MK857_RS02855"
                     /old_locus_tag="MK857_02845"
     CDS             complement(2694..2885)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MK857_RS02855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MK857_02845"
                     /product="hypothetical protein"
                     /protein_id="WP_268700109.1"
                     /transl_table=11
                     /translation="MLKIIDEVKVISKNVTAKQSDISQKHSVLRKEVQHDILQGKKSLS
                     GKSDNFHQRYNHYFQSSK"
     gene            3069..4211
                     /locus_tag="MK857_RS02860"
                     /old_locus_tag="MK857_02850"
     CDS             3069..4211
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051793.1"
                     /locus_tag="MK857_RS02860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02850"
                     /product="site-specific integrase"
                     /protein_id="WP_268700110.1"
                     /transl_table=11
                     /translation="MFVEEHKSGKINFGERYKNPYTGKWQKVTVLMEKDTPRIRKEAQR
                     ILQAKIAAKLSTLESSEMPFTELFNSWWTFHKQELKRSSIASLQGNVNEVREHFGIGIK
                     VTKIDVRYVQHYLDNLECSVSKKERTKTLLNQAFDYAVSLNIIQDNPARRAKLPRVKKT
                     LEDWKKIEQKYLEENEIQPFLKEFRRRPNTYRLALLAEFISLNGGRISEIVSIEPANIN
                     FETRILQLHGTYDHTDGYQNGEKTSPKTPASYRETFMTKREMEIIKEFQFMNEIEKNTN
                     HRFKDMGYIFTTKNGVPIQTNSFNEAAKKANLRLEKPIPKEITSHIFRHTLVSRLAENG
                     TPLKAIMERVGHSDAKTTIQIYTHVTKKMKTDVTNILEKY"
     gene            complement(4300..4575)
                     /locus_tag="MK857_RS02865"
                     /old_locus_tag="MK857_02855"
     CDS             complement(4300..4575)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1132: DNA-binding
                     protein HU 1"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /locus_tag="MK857_RS02865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02855"
                     /product="HU family DNA-binding protein"
                     /protein_id="WP_003063767.1"
                     /transl_table=11
                     /translation="MANKQDLIAKVAEATELTKKDSAVAVDAVFSAIESFLSEGEKVQL
                     IGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(4669..5271)
                     /locus_tag="MK857_RS02870"
                     /old_locus_tag="MK857_02860"
     CDS             complement(4669..5271)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853723.1"
                     /locus_tag="MK857_RS02870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02860"
                     /product="DUF2140 family protein"
                     /protein_id="WP_117479325.1"
                     /transl_table=11
                     /translation="MKLKKNGKKINWWKWGFLLILSINIAFVGVVASRLIQVREPAVES
                     GSSKKTDSVKVGTFSTNREQLNDTVAAYLEDYQTDQMSYTVYATSSAIMFEGTYTLLGS
                     KVPLYIYFQPSRLDSGAVQLKITSFSVGTLSLPESEVLKYIKSSYKLPSFVKVLPNESA
                     ININIQNLKNGADLYLKATTIDLVGNQFNFDIYKKND"
     gene            complement(5240..6088)
                     /locus_tag="MK857_RS02875"
                     /old_locus_tag="MK857_02865"
     CDS             complement(5240..6088)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642837.1"
                     /locus_tag="MK857_RS02875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02865"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_003063748.1"
                     /transl_table=11
                     /translation="MSKKKNILTGFAFFLASLLLFIVIFSVLIPKSDTELTKKDFLAQE
                     ATPFHYVAIGDSLTEGVGDTTNQGGFVPLLAQSLTDTYDYQVTDSNYGVSGNTSKQILQ
                     RMQEKTDIQKSLVKADMMTLTVGGNDVMAVIRKNLTSLSVSTFTKPAKSYQKRLRQIIE
                     LARAENEDLPIYILGIYNPFYLNFPDMTEMQEIVDNWNNATESVTEEYANVYFVPINDD
                     LYKGINGEEGIVSTSGDQTTVINDVLFSGDHFHPNNIGYQIMSDVTMEKISETKEEWKE
                     D"
     gene            complement(6081..6917)
                     /locus_tag="MK857_RS02880"
                     /old_locus_tag="MK857_02870"
     CDS             complement(6081..6917)
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264715.1"
                     /locus_tag="MK857_RS02880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02870"
                     /product="DegV family protein"
                     /protein_id="WP_013851580.1"
                     /transl_table=11
                     /translation="MSKIKIVTDSSLTIEPELVEKYDITVIPLSVMIDGVVYSDSDLKE
                     EGKFLNMMRNSKELPKTSQPPVGVFAEVYENLMKNGADHIVSIHITHTLSGTVEAARQG
                     ANLAGADVTVIDSTFTDQCQKFQVVQAAKLAQEGGSLEEVIAKIEEVRQKSELFIGVST
                     LENLVKGGRIGRVTGLISSLLNIKVVMEMVDCELNPIIKGRGLKTFNKWLDNFIEYAKG
                     KKVAEIGISYCGTADMANGFKEKLQVLGAPIAVLETGSIIQTHTGENAFAVMVRYE"
     gene            complement(7055..8713)
                     /gene="recN"
                     /locus_tag="MK857_RS02885"
                     /old_locus_tag="MK857_02875"
     CDS             complement(7055..8713)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014619981.1"
                     /locus_tag="MK857_RS02885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02875"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_003063744.1"
                     /transl_table=11
                     /translation="MLLEISIKNFAIIEEISLTFENGMTVLTGETGAGKSIIIDAMNLM
                     LGARASLDVIRHGANKAEIEGLFSVGENPALTQILEENGIDVTEELIIRRDILQNGRSI
                     GRINGQMVNLTTLRAVGQYLVDIHGQHDQEELMKPNMHIRMLDEFGNEQFADVKKHYQE
                     LFESYRQLRKRVVTKQKNEQEHKARIEMLEFQIAEIEAAALKSGEDQVLNQKRDKLLNH
                     KNIADTLTNAYVMLDDEEFSSLSNIRSAMNDLMTLEEFDADYKEMSANVSEAYYILEEV
                     TKHLGDVIDDLDFDAGSLQQIEARLEVIYSITRKYGGSVDDVLEYYDNITKEYNLLTGN
                     DESSDDMEKALKRLEKELIVAAEELSQERHALAKNLEAEIKQELADLYMEKADFQVQFT
                     KGKFNRDGNETVEFYISTNPGEGFKPLVKVASGGEISRLMLAIKSAFSRKEDKTSIVFD
                     EVDTGVSGRVAQAIAQKIYKIGSNGQVLAISHLPQVIAIADYQFFIEKRSDENTTVSTV
                     RLLTEEERVEEIAKMLAGSDITEMAREQARELLKK"
     gene            complement(8727..9197)
                     /locus_tag="MK857_RS02890"
                     /old_locus_tag="MK857_02880"
     CDS             complement(8727..9197)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853719.1"
                     /locus_tag="MK857_RS02890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02880"
                     /product="ArgR family transcriptional regulator"
                     /protein_id="WP_003063742.1"
                     /transl_table=11
                     /translation="MKKSERLELIKRIVAENAVETQHDLLKLLEAEGLTLTQATVSRDM
                     NEIGIIKVPSPEGPYIYGLSKDKTKKVGQVSVPIKSTVLAISEETAGLENMINLDVNPG
                     NSRLIKRFLLEDFKDVIFSILADDDSLLVVTKTAEGAAAIRQEVLKWMKDCN"
     gene            complement(9184..10008)
                     /locus_tag="MK857_RS02895"
                     /old_locus_tag="MK857_02885"
     CDS             complement(9184..10008)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /locus_tag="MK857_RS02895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02885"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_003063741.1"
                     /transl_table=11
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVNVINGERYDKPGE
                     KIDDGTELKLKGEKLKYVSRGGLKLEKALQVFEISVDGQTTIDIGASTGGFTDVMLQNG
                     AKLVYAVDVGTNQLVWKLRQDERVRSMEQYNFRYAELADFTEGQPTFASIDVSFISLNL
                     ILPALHNILADNGQVVALIKPQFEAGREQIGKNGIVRDKAVHQKVLENVTDFALNYGFI
                     VKGLDFSPIQGGHGNIEFLVYLEKSADAQDLVTAMIPEIVEKAHKEFKDEKE"
     gene            complement(10001..10870)
                     /locus_tag="MK857_RS02900"
                     /old_locus_tag="MK857_02890"
     CDS             complement(10001..10870)
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063739.1"
                     /locus_tag="MK857_RS02900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02890"
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_058692787.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-51, bitscore:
                     168.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKLNEINQAIRRYYAQSDVVSPDLIEAILYSVEAGGKRIRPLIF
                     LEILEGFGIELTEGHFEVAAALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFDEATA
                     ILAGDSLFLDPFGLVADTALSADIKVRLIAELSQASGTYGMVGGQMLDMKGEERKLNLS
                     ELQLIHTNKTGKLLTFPVVAAGIVANLAANDLKSLREAGSLVGLAFQVRDDILDVTATF
                     EEIGKTPKKDLLADKATYPSLLGLEKSYDILNRSIDQALAIFQKLSETQAFNAEKITKM
                     IERLRLNA"
     gene            complement(10870..11085)
                     /locus_tag="MK857_RS02905"
                     /old_locus_tag="MK857_02895"
     CDS             complement(10870..11085)
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /locus_tag="MK857_RS02905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02895"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_058692786.1"
                     /transl_table=11
                     /translation="MPNKKTFEENLQDLEAIVTKLENGDVALEDAIAEFQKGMVLSKEL
                     QKTLKSAEKTLVKVMQADGTETEMDA"
     gene            complement(11075..12403)
                     /gene="xseA"
                     /locus_tag="MK857_RS02910"
                     /old_locus_tag="MK857_02900"
     CDS             complement(11075..12403)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961637.1"
                     /locus_tag="MK857_RS02910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02900"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_058692785.1"
                     /transl_table=11
                     /translation="MSDYLSVSSLTKYLKLKFDRDPYLERVYLTGQVSNFRRRPTHQYF
                     SLKDENAVIQSTMWAGTFKKLGFELEEGMKINVVGRVQLYEPSGSYSIIIEKAEPDGIG
                     ALAIQFEQLKKKLAEAGYFDERHKRQLPQFVKKIGVVTSPSGAVIRDIITTVSRRFPGV
                     EILLFPTKVQGEGASQEVAANIAKANERDDLDLLIIGRGGGSIEDLWAFNEEIVVQAIF
                     ESRLPVISSVGHETDTTLADYVADRRAATPTAAAELATPVTKADIISWIAERQNRAYQA
                     SLRMIKQKQERLDKLAKSVIFRQPERLYDGYVQKLDRLTTQLMNTMQTQFNQASQRQQL
                     LNQRLLAVDLGSNIRRYQERLEAFQRLLISNMTSQYDSKLARFEKAQDALLSLDTSRII
                     ARGYAMVQKNEEIISSVTDVAVGDQLTVRLRDGQLEVEVKDAK"
     gene            complement(12605..13441)
                     /locus_tag="MK857_RS02915"
                     /old_locus_tag="MK857_02905"
     CDS             complement(12605..13441)
                     /GO_function="GO:0052855 - ADP-dependent NAD(P)H-hydrate
                     dehydratase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851577.1"
                     /locus_tag="MK857_RS02915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02905"
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="WP_003063733.1"
                     /transl_table=11
                     /translation="MIIDELLAHQVITKRQPHSHKGTYGRVLLIGGFYPYGGAIIMSAL
                     ATVKSGAGLVTVATECDNIAALHSHLPEAMAFDCDDKELFYENLTKADVVLIGPGLGEN
                     SKAEVVFQMVLEHISEHQILIIDGSALNLLAKAKPITVKTNHLILTPHQKEWERLSGIA
                     ISNQTIENTKAALQEFPEQTVLVAKSHQTKIIQGNQVGELTVGGPYQATGGMGDTLCGM
                     IAGFVAQFKDNLLNSVATATYLHSYIADQLSDQVYVVLPTTISAELPRIMKEFSER"
     gene            complement(13438..14292)
                     /locus_tag="MK857_RS02920"
                     /old_locus_tag="MK857_02910"
     CDS             complement(13438..14292)
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961632.1"
                     /locus_tag="MK857_RS02920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02910"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="WP_003063732.1"
                     /transl_table=11
                     /translation="MATIIDGKALAVKKQTELVEKVEKLKAETGVVPGLVVILVGDDPA
                     SQVYVRNKERSAKKAGFLSETVRLSESISEEELIQVIAQYNEDDRFHGILVQLPLPAHI
                     NDKRVILAIDPKKDVDGFHPINTGHLWNGRPVMVPCTPAGIMELLREYDIDLEGKTAVI
                     IGRSNIVGKPMAQLLLDKNATVTLAHSRTRHLARVTKQADVLIVAIGQGHFVTKEFVKE
                     GAVVIDVGMNRDDNGKLIGDVKFDEVEPLASFITPVPGGVGPMTITMLMEQTYQSALRS
                     VKA"
     misc_feature    14249..14258
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     misc_feature    14355..14369
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 26.74"
                     /tool="antismash"
     gene            complement(14446..14586)
                     /locus_tag="MK857_RS02925"
                     /old_locus_tag="MK857_02915"
     CDS             complement(14446..14586)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063731.1"
                     /locus_tag="MK857_RS02925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02915"
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="WP_003063731.1"
                     /transl_table=11
                     /translation="MSTIIIAAIIAFAVFMGFRSFIKGKGSCGDCDCNCPVKDEMHKTA
                     K"
     gene            complement(14591..16729)
                     /gene="feoB"
                     /locus_tag="MK857_RS02930"
                     /old_locus_tag="MK857_02920"
     CDS             complement(14591..16729)
                     /GO_function="GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="feoB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642824.1"
                     /locus_tag="MK857_RS02930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02920"
                     /product="ferrous iron transport protein B"
                     /protein_id="WP_058692784.1"
                     /transl_table=11
                     /translation="MTEIALIGNPNSGKTSLFNLLTGTSQRVGNWPGVTVERKSGTVKR
                     HSDWKVQDLPGIYSMSPYTPEEKVARDYLLSNHADSILNVVDSTNLERNLYLTTQLIET
                     GIPVTVALNMSDALKGQGKTINIDKLSYQLGVPVVSTSAIKNTGVDKVIKKAAYTTKET
                     VDTIQYPTYSDKFEATLKQIIDILGDIVPECSARFYAIKFFERDALVQNEVELSEFQKG
                     EINEVIKITEDIFTEDSESIVVNERYEFIERVAKMAQNQDSNFKMTISDKIDRVVTNRI
                     LALPIFAIVMFLVYYLSIQTVGTMWTDWVNDVLFGDLVPNWVQAGLDYLHVSGWLESLI
                     IDGIVAGVGTVLGFLPQIFVLFICLGILEDIGYMSRIAFVMDRVFRRFGLSGKSFIPML
                     IATGCGVPAIMASRTIENERDRRITIMTATFMPCSAKLEIIALIAGAFFPDNPFVAPST
                     YFIGFLTIILSGIALKKTSFLGSYVSPFIMELPAYHMPKVWSVLRYAFGKAMSFVKRAG
                     TIIFSLTVIIWFMSSYDFAFQAVDTEYSILAALGRAIAWIFQPLGFGDWKATVAAATGL
                     AAKEAVVGTFGVLYNDSTTSGLYHALQLDYTSLAAYSFLTFNLLCAPCFAAMGAIKREM
                     GDAKWTIGAIGFQTGLAYVVSLIIYQLGLVVFYGKGITFWTIVAVILLIAIIYFIVRKP
                     RQVKEKVITLDNLEIAGE"
     gene            complement(16726..17202)
                     /locus_tag="MK857_RS02935"
                     /old_locus_tag="MK857_02925"
     CDS             complement(16726..17202)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019802862.1"
                     /locus_tag="MK857_RS02935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02925"
                     /product="ferrous iron transport protein A"
                     /protein_id="WP_013851576.1"
                     /transl_table=11
                     /translation="MILQNAKIDIPYAVVGIDLPDESVRHLSNLGLKVGASLKVVSKTP
                     TSAIVMLKSSRLAFDQSILNHVDVTEEEGELETLPLSELKVGEFAYVDGIYAINEAKRR
                     LMDMGLTRHTKVYLRKVAPLGDPIEISLRGYELTLRKSEAQMISVVKVDSKEKK"
     misc_feature    17184..17196
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: medium, score: 22.86"
                     /tool="antismash"
     misc_feature    17222..17235
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.35"
                     /tool="antismash"
     misc_feature    complement(17223..17236)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.88"
                     /tool="antismash"
     misc_feature    complement(17323..17336)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.47"
                     /tool="antismash"
     misc_feature    17356..17369
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.54"
                     /tool="antismash"
     misc_feature    17403..17416
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.06"
                     /tool="antismash"
     gene            complement(17569..18303)
                     /locus_tag="MK857_RS02940"
                     /old_locus_tag="MK857_02930"
     CDS             complement(17569..18303)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019805208.1"
                     /locus_tag="MK857_RS02940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02930"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_003063728.1"
                     /transl_table=11
                     /translation="MSEMLISIKGLHKYFGKNEVLKGIDLDIKSGEVVVIIGPSGSGKS
                     TFLRTMNLLETPTKGMITFEGVDITDKKNDIFKMREKMGMVFQQFNLFPNMTVLENITL
                     SPTKTKGISKAEAEAKAYDLLDKVGLRDKSDVYPASLSGGQQQRIAIARGLAMDPDVLL
                     FDEPTSALDPEMVGEVLGVMQDLAKSGMTMAIVTHEMGFAREVADRVIFMDGGVIVEQG
                     TPEEVFEQTKEARTKDFLSKVL"
     gene            complement(18303..18989)
                     /locus_tag="MK857_RS02945"
                     /old_locus_tag="MK857_02935"
     CDS             complement(18303..18989)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318135.1"
                     /locus_tag="MK857_RS02945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02935"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_003063727.1"
                     /transl_table=11
                     /translation="MDFSFLPKYWAYFNYGVLVTIMISACVVFFGTIIGILVALVKRTN
                     IKVLNWIASFYVWVFRGTPMVVQIMIAFAWMHFNNAPIVGFGVLDLDFSRLLPGIIIIS
                     LNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPVNAMRYVILPQALKNILPALGNEFIT
                     IIKDSSLLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMVTTVMSFLVKRLEKRM
                     GNGGSN"
     misc_feature    complement(19137..19155)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.05"
                     /tool="antismash"
     misc_feature    complement(19138..19154)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.25"
                     /tool="antismash"
     gene            complement(19244..19474)
                     /locus_tag="MK857_RS02950"
                     /old_locus_tag="MK857_02940"
     CDS             complement(19244..19474)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /locus_tag="MK857_RS02950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02940"
                     /product="DUF1797 family protein"
                     /protein_id="WP_003063726.1"
                     /transl_table=11
                     /translation="MESHLVRIINRLELMTTDSSNLKRNFERDGVVVAEVSFSNDPENG
                     PVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(19609..20589)
                     /gene="argF"
                     /locus_tag="MK857_RS02955"
                     /old_locus_tag="MK857_02945"
     CDS             complement(19609..20589)
                     /EC_number="2.1.3.3"
                     /GO_function="GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /gene="argF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851575.1"
                     /locus_tag="MK857_RS02955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_02945"
                     /product="ornithine carbamoyltransferase"
                     /protein_id="WP_048791204.1"
                     /transl_table=11
                     /translation="MAINDSFLKEIDFTKEELVELIDLGLKFKELKKKKIPHKYLEGLN
                     IALIFEKTSTRTRSAFTVAGQDLGMNVTYLGSSEIQLGKKESVIDTAKVLGSMFDGIEY
                     RGFKQEDVEALAEYSGVPVWNGLTDTWHPTQMIADFMTLKEVFGKLEGLTIAYVGDGRN
                     NMANSLLVTSAILGVNVKIIAPASLQPEAEIIEVAQKYNNGAELTITDDLAAVKGVDML
                     YTDVWVSMGEKVDFKERIDLLLPYQINAELLAKTENPDVIVMHCLPAFHDLNTEIGQEI
                     YDKYGLAELEITDEIFQKYSSIIFQEAENRMHSIKAIMYNSLKAI"
     misc_feature    complement(20738..20751)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.38"
                     /tool="antismash"
ORIGIN
        1 actataacgt tgctcaaagt gattttgaac aagcattaaa caatatttac gaagaagcaa
       61 taacaagcaa ctattcttat aatgacattg aaccgttaca agctttgttt attgcaaaaa
      121 ctgcttttat tcgtgataaa tatgttagtc aagatttgct tttgaaagat gttagcgacg
      181 aagatatcaa taatctttat attgaaagac tagctgatgt ccaaaccttg cctgctgagt
      241 ttgaacaatc agaagttgaa aaacattctg aacgatttaa gaaaaatcat tctattgtac
      301 aagaagcgat tgacaaaatt aaaactgata ttattgaaaa atcatctggt tttgttgttt
      361 cagaacctat caaaatctat tacacttccg ctgctaaagc tggtcctaaa ggttttggtt
      421 atgatgatta tgattcagat tttgcataca ctaatgaaga accaccacgc tatgacatag
      481 ccactgaagt aaatggtaat tctatgaatc cagattatca agacggtgac attctttatt
      541 tacgagatta tggaactact acatacgacg gtgaagaatg tgttgttgtc atcaatgaca
      601 aatcatattt taagaaattg tacactatcg aaaatgggct actgcttgtc tcaattaatc
      661 cagataaaga caagtaccct gatattgaaa tagaattccc accaactgac ggtgaccata
      721 taaaaatatt taatgtagta ggtagtttta cacctataga ttgtgattaa aaaggagtac
      781 gattatggaa tcagaaacta gaccaatgga aattgtctgc tatgacttag attgccattg
      841 caatagacgt cgagagtgga taaaggtaaa tggcgaatgg caccctattg agtactcggt
      901 agatgaccca aatgacccac caatgagtga ggaagaaaaa caaaaacttg ctgatataat
      961 tcttgaattt acagcagaaa aataaaacta tgtgcaatca ctgaaccaca ctaaaagctg
     1021 agaatggaga attattaatg aagaaaattg gtttactagg attaacttta ttatctgttg
     1081 caacacttag cgcgtgttct tcatcaaaga cagacaataa aaatacttct tcaagttcat
     1141 ctgtagagca gactacttct tctacatctg ctgaagagac taaaaaagca gttagatcag
     1201 tttatgactc tgtagttgtt ggtgatttaa tgaataatgg tgaaggtgga acaacaaaag
     1261 acactgttat aaatgcttat ggaaatccag cttctacttc tacaacatca ttaaatggta
     1321 tgaacgtaga acaagtcact tggattggta atggtaacgc tactggcatt acgatatcaa
     1381 ttcaatttat caacaataat gctactagta aaatgatttc tggtttccaa ttctctcgtg
     1441 attctaaaat tggtttgact gaattcaata atttagcaac tggcacttct tatgctgacg
     1501 tagtaaacac actgggtgaa cctgatacaa caagtgaaag tttgatttct ggttcaaaat
     1561 ctgtcacagc aaactggatt actggtatca aaggtaacgt cggtgcaaac tttgttttac
     1621 aatttactaa tgatagctta acaagtaaat cacagtctgg tttgactgac taaaagggga
     1681 actatgaaaa gggatttaaa agaacttatc caagaactac ttgaacatat cgataacaat
     1741 ccattgactg atgaacaaat tgaaaaaatc gaaaaatgga aaaatgggtt gaggagaata
     1801 ggaaagaaag gtaggagtac tgtgaaagaa attatttact tagatactgt ttttgttaat
     1861 tcaatattag cccaaatgaa caaaggttta gtgacaaaac ttgttaatga ggatatggaa
     1921 acagattcaa gctctgattc atcaaccgaa tctactactt cctccggaag tatgggaatt
     1981 aacaaaataa tagccgctaa tactacacat tctgaattag aatccgaaac atcacaagtc
     2041 gtcttttcaa aatccaataa agatttaata gaaactgcaa ttgatgatta ttcattagat
     2101 ttactactaa atgatttaaa agctaataat tttattatta atcaaaatta tggcgacggt
     2161 gatgtgattc aaattgaagg tgagttaact acatatgact tcaagcaact cgcaaatgct
     2221 tcatctttgg aagaaattga atttttgcta cctgattatg atgaatataa aaagaatgct
     2281 gctgagtata ataaaatcaa aaataaaaat ataccaagag cagacgaatt aaaagaatac
     2341 ctttctggaa atggttggca gaattttgac aatttaaaaa atatgtctag ttacttagac
     2401 aaactattac caaatacaag tataattaaa gtcaatgatg cgctctgtat tgtttcggat
     2461 aaactacttc gtgtacaaaa atcacaatta agttttatgc agcttggaaa gagaaaagta
     2521 aaaatgctcg gcatttgttc atcaactatt gacgaacgtg taccaagcaa ctttgatagt
     2581 atggcaaata gccaatattt aattagatac gcccctacta ccattatcaa tattatgtta
     2641 gggtctttca atttaattaa cggtggtgat catatcgtta gaccaattgc tatttacttt
     2701 gaagattgaa aatagtgatt atacctttgg tgaaagttat cagatttacc agaaagactt
     2761 ttctttcctt ggaggatatc gtgttgaact tcttttctta aaacactatg tttttgagat
     2821 atatctgact gctttgcagt tacattctta gaaataactt taacttcatc aataatcttt
     2881 aacattacac caccccgtga tatttgtctt gtttagcgta ttataacata aattaagcta
     2941 aacaaaaaat ccctacactc cctgtcgcca aacttagagt gtaaggaata attggtagta
     3001 tagtaaaaac ctgcatgtgg taggtctctt tactataccc attttaacaa aaaagtgagg
     3061 taaaaacaat gtttgtagaa gaacacaaaa gcggaaaaat aaattttggt gaacgttata
     3121 aaaatccata tacaggtaaa tggcaaaaag ttactgtttt gatggaaaag gacacaccaa
     3181 gaataagaaa agaagctcaa agaattcttc aagctaaaat agctgcaaaa ttaagcactc
     3241 tagaatcgtc tgagatgcca tttacagagc tttttaatag ttggtggact tttcacaagc
     3301 aagagttaaa acgatcgtct attgcttctt tacaaggcaa tgtaaatgaa gtgagagaac
     3361 actttggcat aggcataaag gttactaaaa ttgatgtcag atatgttcaa cactatcttg
     3421 ataacttaga gtgctccgtc agcaagaaag aacgtacaaa aactctgctt aaccaagcat
     3481 ttgattatgc tgtgtctcta aacatcatac aagataatcc agctagacgt gccaaattac
     3541 ccagagttaa aaaaacctta gaagactgga aaaaaatcga acaaaaatat cttgaagaaa
     3601 atgaaattca accattttta aaagaattta ggcgaagacc taacacatat agacttgctt
     3661 tattagccga atttattagt ttgaatggtg gacgaataag tgaaattgtt agtatagaac
     3721 ctgcgaacat caactttgaa accagaattc ttcaactaca cgggacatat gatcacacag
     3781 atggatatca aaatggtgaa aaaacctctc ctaaaacacc tgcatcctat cgtgaaacgt
     3841 ttatgacaaa acgagaaatg gaaatcatca aagaatttca attcatgaac gagattgaaa
     3901 agaatactaa ccatcgtttt aaagatatgg gatatatttt taccactaaa aacggagttc
     3961 cgattcaaac taactcattt aatgaagcag ctaagaaagc aaacctaaga cttgaaaaac
     4021 caataccaaa agagattact agtcacatct ttaggcatac tctcgttagt cgtttagcag
     4081 aaaacggaac tcctttaaaa gcaatcatgg aacgagtggg acactctgat gctaaaacta
     4141 ctattcaaat ttacactcac gtaaccaaaa aaatgaaaac agatgtaaca aatatacttg
     4201 aaaaatactg attttttgtc ccaaatttgt cccacaacac taaaaaaagc ctaccataca
     4261 agttgtaaca cttgatatga taggcttttt aaatgtaaat tattttacag catctttaag
     4321 tgctttacca gctttgaacg caggtacttt tgaagctgca atttcaattt cttcaccagt
     4381 ttgtgggtta cgacctttac gagctgcgcg ttcgcgaact tcaaagttac caaaaccgat
     4441 taattgaact ttttcgcctt cagaaaggaa gctttcgatt gctgagaata ctgcatctac
     4501 agctactgct gaatcttttt tagtaagctc agttgcttct gcaactttag cgattaaatc
     4561 ttgtttgtta gccatttaac aaatcctcca attaatttct aagcgttaac actttaacac
     4621 gttctatgat acccaaaaat agcttttagg tcaagtatta aacgtctttt agtcgttttt
     4681 cttgtaaata tcaaaattga attgattacc tacaagatca atagtagtgg ccttcaaata
     4741 aaggtctgca ccatttttta gattttgaat attaatattg atcgctgact cgttcggtaa
     4801 aactttaaca aaacttggca atttatagct tgattttata tattttaaaa cctctgattc
     4861 aggcaaggaa agtgtaccaa ctgaaaatga tgtaatttta agctgaaccg caccagaatc
     4921 aagacggcta ggttgaaaat aaatataaag tggcacttta gagcctaaaa gggtatatgt
     4981 cccttcaaac ataatcgctg atgatgtagc atagacggta taggacattt ggtctgtctg
     5041 ataatcctcc agataagcag caacagtgtc gtttaattgc tcacgatttg ttgaaaaagt
     5101 cccaacttta acgctatccg tttttttaga actaccgctc tcaaccgctg gttctctcac
     5161 ttgaatcaaa cgactagcaa caacgcccac aaacgcaata tttatagaca aaatgagaag
     5221 aaatccccat ttccaccaat taatcttctt tccattcttc tttagtttca ctgattttct
     5281 ccattgttac atctgacatg atttggtaac caatattatt tgggtgaaaa tggtcaccgc
     5341 taaaaaggac atcattaatc acggttgtct ggtcaccaga agttgaaaca atcccttctt
     5401 caccattaat tcccttatat aagtcatcgt tgataggtac aaaatagaca ttggcatact
     5461 cttcggtgac actttcagta gcgttattcc aattatcgac gatttcttgc atttccgtca
     5521 tatcagggaa attgaggtag aatggattgt aaatgcccaa aatataaatt ggcaaatctt
     5581 cattctctgc acgcgctaat tcaataatct gacgcaagcg tttttgataa gatttggcag
     5641 gtttggtaaa agtagaaaca gacaaactcg ttaaattctt tcgaataact gccatgacat
     5701 catttccacc aacggttagg gtcatcatat ctgccttaac caatgatttt tgaatgtctg
     5761 tcttttcttg catccgctgc aaaatttgct tgctggtatt tccagaaaca ccgtaattac
     5821 tatcagtaac ttgatagtca taagtatctg ttaaactttg cgccagcaaa ggaacaaaac
     5881 caccttggtt agtagtgtca ccgactcctt ccgtcaacga atcaccaatc gccacataat
     5941 gaaacggtgt cgcttcttgt gccaaaaaat ctttctttgt tagctctgta tcagattttg
     6001 gaatcagcac actaaaaatg acaataaaca gaagaaggct tgctaaaaag aaagcaaacc
     6061 cagttaaaat attctttttc ttactcataa cgtaccatta ccgcaaaggc attttcacca
     6121 gtgtgtgttt ggataattga acctgtttca agaacagcaa tcggagctcc taacacttgt
     6181 aacttttcct taaatccatt tgccatatca gccgtaccac agtaagaaat accaatttct
     6241 gctacttttt tacctttagc gtattcaata aaattgtcta gccacttatt gaatgtttta
     6301 aggccacgtc ctttaataat cggatttaat tcacaatcaa ccatttccat aacaacttta
     6361 atgttaagga gtgagctaat aagaccagtc acacgtccga tacgtccacc ttttaccaaa
     6421 ttttcaagcg ttgatacacc aataaaaagt tcagattttt gacgaacctc ttcaatttta
     6481 gcaataactt cttctaaact accaccttcc tgagccaatt ttgcagcttg aactacttgg
     6541 aatttttgac attggtctgt aaaggttgag tcaataacag taacatcagc acctgctaaa
     6601 ttagcccctt gacgcgctgc ttcaactgtc cctgaaagcg tgtgtgtgat atgaatggaa
     6661 acaatatgat cagcaccatt tttcatcaag ttttcataaa cttctgcaaa aacgcctact
     6721 ggtggctgac ttgtttttgg caattcctta ctgtttcgca tcatgttaag gaattttcct
     6781 tcttctttca aatcactatc tgaatacacg acaccatcaa tcatgaccga tagtgggata
     6841 acggtaatat catatttttc aaccaattca ggttcaatag ttaaagagga atccgtaaca
     6901 attttaattt tactcatttt ctatcctatc atactttcga tacttgtatc taaattttat
     6961 tctaacatta attataccaa atttttaaaa cttaggggac attttatcag agaaagtcta
     7021 attgcgcaaa aaagaagcct tgcagcttca ctttttactt cttcaatagt tcgcgagctt
     7081 gttcgcgtgc catttcagta atatcgctac cagcaagcat tttagcgatt tcttctactc
     7141 gttcttcttc ggtcaacaag cgaaccgttg aaacagtcgt attttcatca ctgcgttttt
     7201 cgataaagaa ctgataatca gcaatggcaa tcacttgtgg taaatgagat attgccaaga
     7261 cttgtccgtt acttccgatt ttatagattt tttgggcaat agcttgcgca acgcgaccag
     7321 atacaccagt atccacttcg tcaaagacga tacttgtttt gtcctcttta cgtgaaaatg
     7381 ctgatttgat agccaacatt aaacgagaaa tttcaccacc agacgcaacc ttaacgagtg
     7441 gtttaaagcc ttcaccaggg ttcgttgaaa tgtaaaattc aacagtttca tttccatcac
     7501 ggttgaattt tcctttggtg aattggactt gaaaatcagc cttttccatg tacaaatcag
     7561 ctaactcttg cttgatttca gcttccaaat ttttagccaa ggcatggcgt tcttgactga
     7621 gttcttcagc agcaacaatc aattcttttt ccaagcgttt aagggctttt tccatgtcat
     7681 cagatgactc atcatttcca gtcaaaagat tgtattcctt ggtgatatta tcataatact
     7741 ctaaaacatc atcaacacta ccgccatatt tgcgtgtaat gctataaatc acctctaggc
     7801 gcgcttcgat ttgttgcaag cttcccgcat caaaatcaag gtcatcaatg acatcaccta
     7861 ggtgtttcgt gacttcttct aggatataat aagcctctga aacgttagct gacatttctt
     7921 tatagtcagc atcaaattct tcgagcgtca tcaaatcatt catggctgaa cgaatgttag
     7981 atagacttga aaattcttcg tcatcaagca tgacataagc attggtcaac gtatctgcaa
     8041 tgtttttatg attaagcaat ttatcacgtt tttgattgag tacctggtcc tcaccagatt
     8101 tcaaggctgc cgcttcaatc tctgctatct gaaattctaa catttcaata cgcgctttat
     8161 gctcttgttc atttttttgc ttggtcacga cacgcttacg caattgacga tagctttcaa
     8221 aaagctcttg gtaatgtttt ttgacatcag caaactgttc attaccaaat tcatccaaca
     8281 tccgaatgtg catattgggc ttcatcaact cttcttggtc atgttgtcca tgaatatcaa
     8341 ccagatactg cccaacggca cgtaacgttg tcagattcac catttgtccg ttgatacgac
     8401 cgatagaacg accattttgc agaatgtcac ggcgaataat caattcttct gtcacatcaa
     8461 tgccattttc ttccaaaatc tgtgtgagcg caggattttc accaaccgaa aaaagccctt
     8521 caatttcagc cttgttagcc ccatgacgaa taacgtcaag actagcccgc gcccccaaca
     8581 tgaggttcat ggcatcaata ataatcgact tccccgctcc agtttcccct gtcaaaaccg
     8641 tcatgccatt ttcaaaagta agcgagattt cttcgataat ggcaaaattt ttaatggaaa
     8701 tttctaaaag cattgggtga cctcccttag ttacagtctt tcatccattt aagcacttct
     8761 tggcgaattg ctgctgctcc ttcagctgtt ttggtaacga ctaataaact atcatcgtca
     8821 gcaaggatac tgaaaatcac atctttaaaa tcttccaaca agaaacgttt aatcaaacgg
     8881 ctatttcctg gattcacatc aagattaatc atgttttcaa gccctgctgt ttcttctgaa
     8941 atcgcaagaa ctgtgctttt aattggcaca gaaacttgac caactttttt tgtcttgtct
     9001 tttgaaagcc cataaatata aggaccctca ggtgaaggta ctttgatgat accaatttca
     9061 ttcatgtcac gtgaaacagt agcttgcgtt aatgtcaaac cttctgcttc aagcaatttt
     9121 agcaaatcat gctgtgtctc aacagcattt tcagcaacaa ttcttttgat taattctaaa
     9181 cgttcactct ttttcatctt taaattcctt atgtgccttt tctacaattt ctggaatcat
     9241 ggcagtaact aaatcttgag cgtcagctga tttttccaaa taaaccagaa attcaatgtt
     9301 accatgtcca ccttgaatcg gtgaaaaatc aagtccttta actataaatc cgtaatttag
     9361 agcaaaatct gtcacatttt ccaaaacttt ttgatgaaca gctttatcac gaacaattcc
     9421 atttttacca atctgctcac gtcctgcttc gaattgtggt ttgataagag ccacaacttg
     9481 accattatca gccaaaatat tgtgaagcgc tggcaaaatc aaattcaaag agataaagct
     9541 aacgtcgata ctagcaaaag ttggttgacc ttctgtaaaa tccgccaatt ctgcatagcg
     9601 gaaattatac tgctccatgc tacgaacacg ttcatcctga cgaagtttcc aaaccaattg
     9661 attggtacca acatcaaccg catagacaag ttttgcacca ttttgaagca tcacatcggt
     9721 aaaaccacct gttgaagcac cgatgtcgat tgtcgtttgt ccgtcaacag aaatctcaaa
     9781 aacttgtaaa gctttttcca gtttcagccc accacggcta acgtatttta atttttcacc
     9841 tttaagcttt agctccgtcc catcgtcaat cttctcacct ggtttgtcat accgctcacc
     9901 attaatcaca ttgacaacca aacctgccat aacaccacgt tttgcttgtt cacgcgtttc
     9961 aaaaagccct tgtttatagg caagcacatc aactctttcc ttaggcattt agtcgcaacc
    10021 tttctatcat tttagtgatt ttttctgcat taaacgcttg tgtttccgaa agtttttgga
    10081 aaatagctag cgcttggtca attgatcgat tcaagatgtc atacgatttt tctaaaccaa
    10141 gcaagcttgg ataagtcgcc ttatcagcaa gtaaatcttt tttcggcgtt tttccaattt
    10201 cttcaaacgt tgctgtcaca tctaaaatat catcacgaac ttggaaagct aacccaacca
    10261 agctaccagc ttcgcgcaat gactttaagt cattagctgc taaattcgca acaattcctg
    10321 ccgccacaac tggaaaagtc aacaatttcc ctgttttatt tgtatgaatc aattgcaatt
    10381 ctgaaagatt aagcttgcgc tcttcgcctt tcatatcaag catttgtccg ccaaccatgc
    10441 cataagtgcc tgaagcttgt gataattctg caatcaaacg aactttgata tcagctgata
    10501 gcgcagtatc tgccaccaaa ccaaatggat ctaaaaagag gctatctcct gctaaaatcg
    10561 ccgttgcttc atcaaatttt ttgtggttag tcaaacgtcc acgacgataa tcatcatcgt
    10621 ccattgctgg caaatcatca tgaatcagac tacctgtatg aatcatttca agcgcagctg
    10681 ccacttcaaa atgaccttct gtcaactcga tcccaaaacc ttccagaatt tctaagaaaa
    10741 tcaagggacg gatacgtttt ccgcctgcct ccacagaata aagaatcgct tcaattaaat
    10801 ctggcgaaac aacatctgac tgtgcataat aacgtcgaat tgcctgattg atttcattta
    10861 atttatccat taggcatcca tttccgtttc tgttccgtca gcttgcatca ctttgacaag
    10921 tgttttttca gcagatttta acgttttttg aagctctttt gataacacca tacctttttg
    10981 aaattctgcg atagcatctt ccaaagcaac atcaccattt tcaagtttgg taacaatagc
    11041 ttctaaatct tgtaaatttt cttcaaatgt ttttttattt ggcatctttt acctccactt
    11101 caagctgacc atctcttagt cgaacagtca attggtcgcc tactgccaca tctgtcacgc
    11161 ttgagataat ttcttcgttt ttttgtacca tagcatagcc tctggcaata attcgactag
    11221 tatccaaaga cagcaaagca tcttgtgcct tttcaaatcg tgctaactta ctatcatatt
    11281 gactcgtcat attagatatt aaaaggcgtt gaaaagcttc taaacgctct tgataacgtc
    11341 gaatattact tcctaaatca acagccaaaa gacgttgatt tagcagttgt tgccgttgac
    11401 tagcctgatt aaattgagtt tgcatagtgt tcatcaattg agtcgtcaag cgatccaatt
    11461 tttgaacata accgtcgtat aatcgctcag gttgtctaaa aataacggat tttgctagtt
    11521 tatccaaacg ttcttgtttt tgcttaatca tgcgcaaact agcttgataa gccctatttt
    11581 ggcgctccgc aatccaagaa ataatatcag ctttcgttac tggcgttgct aattcagcgg
    11641 ctgctgttgg tgttgccgct ctacggtcag ccacataatc cgccaaagtc gtatcagttt
    11701 catgtccgac acttgaaata actggcaaac gtgattcaaa aatagcttga acaacgattt
    11761 cctcattgaa cgcccagaga tcctcaatcg aacctccccc acgaccaata atcaaaaggt
    11821 caaggtcatc tcgctcattg gctttagcaa tatttgcagc tacttcctga ctagcgcctt
    11881 caccttgaac ttttgttgga aaaagaagaa tttcaacccc tggaaaacgt cgtgaaacgg
    11941 tcgtgataat atcacgaatg accgctccgc ttggactggt aacaacacca attttcttaa
    12001 caaattgtgg taattgacgc ttatgtcgct catcaaaata accagcctct gctaattttt
    12061 tcttcaattg ttcaaactga atcgctaagg caccaatccc atctggctca gctttttcaa
    12121 taataatcga ataagaacca cttggctcat aaagttggac acgaccaaca acattgattt
    12181 tcatgccttc ttccagctca aaaccaagtt ttttaaaggt tcctgcccac atcgttgatt
    12241 ggatgacagc attttcatct ttcaaagaaa aatattgatg cgttggacga cgacgaaaat
    12301 tggagacctg acctgtcaaa taaacccgct ccaaataagg gtcacgatca aattttaatt
    12361 taaggtattt agtcaaactc gagacactta aataatccga catagcagac tcctttccat
    12421 aaaattccgt acattagaca atttttgcat atcaaagtaa ttatatcaaa aaaactaaaa
    12481 tattgataca atgcgttatc tcgccccact cctcactttc ttttttaaga tttttggatt
    12541 ttaaaaaaac tatccagtgg atagtttcag actgaagaca atgttaatat tgtgttttag
    12601 cgatttatct ctccgagaat tctttcatga tacgggggag ttctgcgcta attgtcgttg
    12661 gtaaaacaac atagacttgg tcgctgagtt ggtcagcgat ataggaatgt aggtacgttg
    12721 ctgtggcaac actgttcaag agattatctt taaactgggc gacaaagcct gcaatcatgc
    12781 cacaaagcgt atctcccata ccacctgtcg cttggtaagg accgccaaca gttagctcgc
    12841 cgacttgatt tccttgaatg attttagtct gatgactttt agccactaaa acggtctgtt
    12901 ctggaaattc ttgcagagct gctttggtgt tttcgattgt ctggttcgaa atagcgattc
    12961 ctgataatct ttcccattct ttttgatgtg gtgtcaatat gagatgattc gttttgactg
    13021 tgattggctt agcttttgcc aataaattca aagcggagcc gtcaataatc aaaatctggt
    13081 gttcagaaat atgctccaaa accatttgaa acacaacttc tgctttgcta ttttccccta
    13141 aaccaggacc aatcaaaacg acatcagcct tggtcaaatt ttcataaaat agctccttat
    13201 catcacaatc aaaagccata gcttctggaa gatgactgtg aagagctgcg atattatcac
    13261 actcagtcgc cacagtcact agtccagcac cgcttttaac cgtggctaaa gcgctcatga
    13321 taatcgctcc accataagga taaaatccac caattaaaag aacacgaccg tatgttcctt
    13381 tgtgagaatg tggctggcgc tttgtaatca cttgatgtgc caataattca tcaataatca
    13441 tgctttcaca cttctaaggg cagattgata tgtttgttcc ataagcattg taatggtcat
    13501 tggaccaacg ccaccaggta ctggtgtgat aaaacttgcg agtggttcaa cttcgtcaaa
    13561 tttaacatct ccaatgagct taccattgtc atcacggttc ataccgacat caataaccac
    13621 tgccccttct ttcacaaatt ctttggttac aaaatgtcct tgaccgattg ccacgattaa
    13681 aacatcagct tgttttgtca cgcgcgccaa atgacgtgta cgagaatgcg ccaaggtaac
    13741 cgttgcattt ttgtccagta atagctgcgc cattggtttt ccgacaatat ttgaacgccc
    13801 aatgatgaca gctgttttac cttctaaatc aatgtcatac tcacgaagca attccataat
    13861 gccagctggc gtacacggta ccatgacagg acgtccattc caaaggtgtc ctgtgttgat
    13921 tgggtggaaa ccatctacgt cttttttagg gtcaattgct agaatcacac gcttatcatt
    13981 aatgtgtgca ggaagtggca attgcaccaa aataccatgg aaacggtcat cctcgttata
    14041 ttgtgcaatc acttgaatca attcttcttc actgattgat tctgaaaggc gaacagtttc
    14101 acttaaaaat cctgctttct tagcagaacg ttctttattt cggacataaa cttgactagc
    14161 tggatcatca ccaacaagaa taacgaccaa accaggcaca acgcccgtct cagcttttaa
    14221 tttttcaact ttttcaacta attcagtctg ttttttgaca gctaaggctt ttccatctat
    14281 aattgttgcc atatcattct ccaaaattgt atttcttcca ttataccaga aaacagcact
    14341 atattctatt ttcttatttt cagaaaattc tttaaaatgt tattaatgct atcttttata
    14401 actataaaaa agcttgccca catgagcaag ctctctcttg ttagtttact ttgctgtttt
    14461 atgcatttca tctttgactg ggcagttaca atcacaatca ccacaagatc cttttccttt
    14521 gatgaaacta cgaaagccca taaacaccgc aaatgcaata attgcagcaa taataatcgt
    14581 tgacatagta ttattctcca gctatttcta gattatctaa agtaatcact ttttctttaa
    14641 cttgtcttgg ttttctaacg ataaagtaaa taatagcaat caacaagata acggctacaa
    14701 tcgtccagaa tgtgatgcct ttaccataga aaacaacaag cccaagttga tagataatca
    14761 aactaaccac ataagcaagt cctgtttgga agccaattgc accaattgtc cacttcgcat
    14821 ctcccatttc acgtttgata gcacccattg cggcaaaaca tggcgcacag agcagattaa
    14881 atgtcaagaa tgaataagct gctagtgatg tgtaatccaa ttgcaaagca tgatacaaac
    14941 cactagttgt gctgtcatta tacaagacac cgaatgttcc aacaacggct tctttggctg
    15001 caagccctgt cgcagctgca acagtagctt tccagtcacc aaaaccaagt ggttggaaaa
    15061 tccaagcaat tgctctacca agagcagcaa ggattgaata ctccgtatca acagcttgga
    15121 aagcaaaatc ataagatgac ataaaccaga taataaccgt caaactgaaa atgatggtac
    15181 cagcacgttt tacaaagctc atggctttac caaaggcata acgtaatact gaccacactt
    15241 ttggcatatg ataagctggc aattccatga taaatggact aacatagctt ccaaggaaac
    15301 ttgttttttt aagcgcaatc cctgataaaa taattgtcaa gaaacctata aaatatgtag
    15361 atggcgcaac aaatggatta tctgggaaaa atgctcccgc aatcaaagcg ataatttcca
    15421 atttagccga acatggcatg aacgttgctg tcataatagt aatacgacgg tcacgttcgt
    15481 tttcaatggt acgactcgcc ataatcgcag gcacaccaca tcctgtcgca atcaacatcg
    15541 gaatgaaaga ttttcctgac aacccaaagc gtcggaacac acggtccatg acaaaggcaa
    15601 tacggctcat gtaaccaata tcttctaaaa tacccaaaca gataaataga acaaagattt
    15661 gtggcaagaa accaagaacc gtaccaaccc ctgcaacgat tccgtcaata atcaatgatt
    15721 ctaaccaacc agatacgtgc aagtaatcaa gaccagcttg tacccaattt ggcaccaaat
    15781 caccaaagag aacatcattc acccagtctg tccacattgt tccgactgtt tgaatagata
    15841 ggtaataaac caagaacata actatcgcaa aaatcggcaa tgccaaaata cggtttgtca
    15901 cgacacggtc gattttatct gaaatcgtca tcttgaaatt actatcttgg ttttgtgcca
    15961 ttttagccac acgttcgata aattcataac gttcattgac aacgatagat tcagaatcct
    16021 ctgtgaaaat gtcttctgtg attttaatca cttcattgat ttcacctttt tggaattctg
    16081 acaattctac ttcattttga accaaggcat cacgttcaaa aaatttaata gcataaaaac
    16141 gtgcagaaca ttctggaaca atatcaccta agatatcaat aatttgtttc aaagtcgctt
    16201 caaatttatc actataagta ggatattgaa tggtatcaac ggtttcttta gtggtatatg
    16261 ctgctttttt gataacttta tcaacacctg tattcttaat agcactagta gaaacgactg
    16321 gaacaccaag ttgataagaa agtttatcga tattaatcgt ttttccttga cctttgaggg
    16381 catcgctcat attaagcgca acggtcacag gaatacctgt ttcaatcaac tgcgttgtca
    16441 aataaaggtt acgttccaag tttgtcgaat caacaacatt aagaatgcta tccgcatgat
    16501 tactcaataa atagtcacgt gccacttttt cttctggcgt ataaggtgac attgagtaaa
    16561 tccctggtaa gtcttgcact ttccaatcac tgtgcctttt aacggtacca ctttttcgtt
    16621 caacagtaac accaggccag ttaccaacac gttgacttgt tccagtcaat aaattaaaga
    16681 gacttgtttt cccactattt ggattcccaa ttaaggctat ctctgtcatt ttttctcctt
    16741 actatctact ttcacaacac taatcatctg cgcttctgat ttacgtaagg ttaactcgta
    16801 accacgtaaa ctaatttcga tagggtctcc taatggcgct actttacgaa gataaacttt
    16861 ggtatggcgt gttaatccca tatccataag gcgacgtttt gcttcattaa tagcataaat
    16921 accatccaca taagcaaatt ctccaacttt caactctgaa agaggcaaag tttcaagttc
    16981 tccttcttct tcagtaacgt caacatgatt taaaattgac tgatcaaatg ccaaacggct
    17041 tgatttaagc atgacaattg cactcgttgg cgtttttgaa acaactttta acgaagcacc
    17101 aacttttaac cctaagtttg ataaatgtcg aacactttca tcaggtaaat caataccaac
    17161 gactgcgtag ggaatatcaa ttttagcatt ttgcaaaatc aaaattcttg acctcctcgt
    17221 aattttttga taaaataatc gaccttctac tcggttcatt atatcataaa aataggacaa
    17281 tttttctata aaaattaatt ttttatttaa ttattcaatt aattgtaata attctaaata
    17341 ataactttat ctatttagaa tcattataat atatgttttc aatcttgttt cattcattta
    17401 caatttttaa aaataattaa aatacaaaaa ttaagcatgc ttaatataaa aactatcatt
    17461 catttatctc taattaaata tttatttttt acatatatta aacttcttcc agaacaagaa
    17521 aaaactcagc tgagtttatg tactcaaccg aggttatttt ttattctatt ataaaacttt
    17581 actcaagaaa tcttttgtac gagcttcttt ggtttgttcg aagacttctt cgggcgttcc
    17641 ttgttcaaca atgacacctc cgtccatgaa gataacacga tcagccactt cacgtgcaaa
    17701 tcccatttca tgggtaacaa tcgccattgt cattcctgat tttgctaaat cttgcataac
    17761 accaagtact tcaccaacca tttctgggtc aagcgctgat gttggttcat caaagagcag
    17821 tacatctgga tccatagcaa gtccacgcgc aattgcgata cgttgctgtt gaccacctga
    17881 caaactagct ggataaacgt ctgatttgtc gcgaagccca actttatcta ataaatcata
    17941 agcttttgct tctgcttctg ctttagagat accctttgtt ttagttggtg ataatgtgat
    18001 attctcaagt accgtcatat ttgggaagag attgaactgt tggaaaacca ttcccatttt
    18061 ttcacgcatc ttgaaaatat catttttctt atctgtaata tcaacaccct caaaagtaat
    18121 catacctttt gtcggtgttt caagtaagtt cattgtacga agaaatgttg attttcctga
    18181 ccctgaaggt ccaatgataa caaccacttc accagattta atatcaaggt caataccttt
    18241 taacacttca ttttttccga aatatttatg aagtccttta attgaaataa gcatttctga
    18301 cattagttgc tacctccatt tcccatgcgt ttttcaagtc gtttcactaa gaatgacatc
    18361 acagttgtca ccatgaggta gtagaatgca gcaaataaca atggtgtgat gggcaaatac
    18421 gttgctgtta cgaccgattg ggcaccattc cacaattcca taactccgat agtttgaaga
    18481 agtgaactat ctttgataat ggtaataaat tcattaccaa gtgctggtaa gatatttttg
    18541 agggcttgcg gcaaaatgac ataacgcatt gcattgactg ggcgaatacc aagcgaatac
    18601 gccgcttcaa gctgtccttt tggtactgct tcgataccag cacggacgat ttcagaaata
    18661 taagctccgc tatttaacga aataataatg atacctggaa gcaaacgtga aaaatcaagg
    18721 tcaagaacac caaagccaac gattggcgca ttattaaagt gcatccaagc aaaggcaatc
    18781 atgatttgaa caaccatcgg agtcccacga aagacccaaa cgtaaaaact agcaatccaa
    18841 tttaaaactt ttatatttgt acgtttaact aaagcaacca agataccaat gattgtccca
    18901 aagaaaacaa cacatgctga aatcataatg gttacaagga caccatagtt aaaataagcc
    18961 caatattttg gcaaaaatga aaagtccatt tatttctcct ataaacaata atcaattaat
    19021 tataacacag attgaataaa aataccaata attcattttt ctggaaacag acgtaaatac
    19081 ttgatataac agcatttcta tcattattaa taaacaaaaa aataaaaagc tcgcaatttg
    19141 cgaacttttt gcaattcaaa atagcaatat aagaaaacgt tgaaaccaca cttaagcagg
    19201 gctttaccaa aaccttatac tctgtcctga atttttcttt attttagtaa agaaggtcat
    19261 aaatttccat tgcgattaaa tcgatgctat caaatgagta agactcacgc gcttcaacat
    19321 cacgcaaagt gaaaactgga ccattttcag ggtcattact gaatgacact tctgccacaa
    19381 cgacaccatc acgttcaaaa ttacgtttta gattactact atcagttgtc attaactcaa
    19441 gacgattgat aattctcacc aaatgtgatt ccatgactat tctcctcttc gtttattgtc
    19501 catactattt taacataatt tcctacaaac aaacaacaaa ggaatgtatt ttctttcttt
    19561 tatctaaaat tcctgtcaaa agtgccattt ttcagcgatt attgtccttt aaattgcttt
    19621 tagtgaattg tacataatcg ctttgataga atgcatacgg ttttcagctt cttgaaaaat
    19681 gattgaactg tatttttgaa aaatctcatc ggtaatttca agttcagcaa gaccatattt
    19741 gtcataaatt tcttgaccaa tttcggtatt aaggtcatgg aaagctggta agcaatgcat
    19801 gacaatcaca tcaggatttt cagttttcgc taatagttct gcattgattt ggtaaggcaa
    19861 taagaggtca atacgttctt tgaaatcaac tttttctccc attgataccc aaacatcagt
    19921 gtaaagcata tcaacacctt taaccgcagc aaggtcatct gtaatggtta attcagcacc
    19981 attgttgtat ttttgagcaa cttcaataat ttcagcttca ggttgcaagc tggctggcgc
    20041 aataatttta acattgacac caagaattgc cgaagtcaca agcaaagaat ttgccatatt
    20101 attacgccca tcaccgacat aagcaatcgt caagccttct aattttccaa aaacttcttt
    20161 taaggtcata aaatcagcaa tcatttgtgt tggatgccaa gtatctgtca aaccattcca
    20221 gactggcaca ccagaatact cagccaaggc ttcaacatct tcttgtttga aaccacggta
    20281 ctcaatcccg tcaaacatcg aaccaagaac ttttgccgta tcaatgactg attccttttt
    20341 accaagttga atctcgctac taccaagata agtcacgttc atgcccaaat cttgcccagc
    20401 caccgtgaaa gctgaacgtg ttcgtgtact tgtcttttca aaaataagag caatgttcaa
    20461 cccctctaaa tatttatgag gaattttttt ctttttcaac tctttaaatt tcaatcctaa
    20521 atcaatcagt tcaaccagtt cttccttagt aaaatcaatc tctttcaaaa atgaatcatt
    20581 aatagccata cactcgtcca tcctttttct ttgaataata tacctaattt tagcataatt
    20641 atacattttg tcaaggagat tttgaataaa aaatcatctc ccccaaaata ccaccacatt
    20701 tgccatttat atttgacatg tcatatataa acacatacaa acaaactttt ctcttgaaaa
    20761 acgtaatagc tattttatca atggattatt tgcgagcgaa gtgagcaaac aagaggttgc
    20821 aaataaatct gataaggtca gcatcattcg taagaaattt ttgtgaatct
//
