LOCUS       NZ_JAPDMW010000005     23056 bp    DNA     linear   CON 23-JAN-2024
DEFINITION  Paenibacillus alvei strain LF-11/2021
            NODE_5_length_505835_cov_30.377313, whole genome shotgun sequence.
ACCESSION   NZ_JAPDMW010000005
VERSION     NZ_JAPDMW010000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus alvei
  ORGANISM  Paenibacillus alvei
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 505835)
  AUTHORS   Fallico,L.
  TITLE     Analysis of the Paenibacillus alvei's inhibition ability against
            multidrug resistant bacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 505835)
  AUTHORS   Fallico,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2022) U.O.C. Microbiologia, Ospedale San Bortolo
            AULSS8 BERICA, Viale F. Rodolfi, 37, Vicenza, Vicenza 36100, Italy
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.14.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 71.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/23/2024 02:12:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,998
            CDSs (total)                      :: 5,902
            Genes (coding)                    :: 5,824
            CDSs (with protein)               :: 5,824
            Genes (RNA)                       :: 96
            rRNAs                             :: 9, 1, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 1, 8 (16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 65 of 78
            Pseudo Genes (internal stop)      :: 14 of 78
            Pseudo Genes (multiple problems)  :: 27 of 78
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:37:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 23056
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAPDMW010000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23056
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..23056
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23056
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<4:3056](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <5..3056
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     gene            <1..3056
                     /locus_tag="OF778_RS11540"
     CDS             <5..3056
                     /NRPS_PKS="Domain: AMP-binding (36-431). E-value: 2.9e-111.
                     Score: 363.9. Matches aSDomain:
                     nrpspksdomains_OF778_RS11540_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (536-606). E-value: 1.3e-15. Score:
                     49.4. Matches aSDomain: nrpspksdomains_OF778_RS11540_PCP.1"
                     /NRPS_PKS="Domain: TD (638-885). E-value: 2.4e-44. Score:
                     143.3. Matches aSDomain: nrpspksdomains_OF778_RS11540_TD.1"
                     /codon_start=3
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005543184.1"
                     /locus_tag="OF778_RS11540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_268624575.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-119, bitscore:
                     394.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.2e-10, bitscore:
                     35.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 5.5e-43, bitscore:
                     141.6, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SIGQMQLISEAETKQQLEIWNRTETAYPRDPVIQELFEEQAAARP
                     EAVAVVDEDRQLTYGELNARANQLAHYLRKKGVKPETLVGICMERSADLIVGILGILKA
                     GGAYVPMDPSYPQQRLTYMTQDAGIELMVTQSETSGWVPEPITRICLDSAADQEMLSQE
                     SDRNPSITTTPHNMAYLIYTSGTTGNPKGVMVEHHTLINMVFWHQQFFQVTEQERASQI
                     ASIAFDAAVAEIWPYLSRGASLHVCKESVRTDPAALQNWVVEQQITIGFMPTQMAEIMI
                     HLPWPSHTSLRCLLTAGDMLRQSPPASLPFALINNYGPTECTVVATATEVSPLQEGIPP
                     IGGPIANTKLYVLDPYQQPVPIGVAGELYIGGAGVTRGYLNRPELTEERFLPDPFSGES
                     GAKMYRTGDAVKYQPDGNLIYVSRIDDQVKIRGFRIELGEIEMVLSQLPAIKQAVVIVR
                     EDRPGEKQLAAYLVGEGSAQEWRTYLSERLPSYMVPTYFVQLDSLPLTPNGKIDTKSLP
                     KIDSVLQTSASYIAPRHATERKLVQIWSSVLGMKETSIGVHDSFFDLGGHSMKIMEALA
                     KGLTEGWHVTVKDYYDLQTIQKIAQKIDHGSKKYLHSDTSRLQFLKPPKKDIAHATYDP
                     IGNVLLTGVTGYLGIHLLAELLDGTNSRVYCLIRGSDPRNRLLEQISFYFHDKFEKYKV
                     MLSSRVVIVKGDLSEKQFGLSDAEYAQLDSTISSVIHSAALTKHFGNYADFEKANVTTL
                     EELISFVGRNKRLHYMSTMSVSGHITFGEEQHVFTENDFYVQQNYEDNVYVKSKFWAEH
                     ALFQAISNGVDAAIYRVGNLTNRHSDGQHQHNIADNAFMSRFKFMLQHGVASNQFISND
                     IEFTPVDACSRAVVALIKADASAGENYVFHVYNHHKVGLGEVVQLLHKSGHEIALLDGV
                     AFQDLMLRLSQDDKHIHDIQMLMAAGEQLEGDYAIVKHDSLQTQIALSKAGFYWPKIDA
                     LYMQKIVTYLQNSGYLPVNEMRSLIQHV"
     aSDomain        114..1298
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_OF778_RS11540_AMP-binding.1"
                     /evalue="2.90E-111"
                     /label="OF778_RS11540_AMP-binding.1"
                     /locus_tag="OF778_RS11540"
                     /protein_end="431"
                     /protein_start="36"
                     /score="363.9"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="FEEQAAARPEAVAVVDEDRQLTYGELNARANQLAHYLRKKGVKPE
                     TLVGICMERSADLIVGILGILKAGGAYVPMDPSYPQQRLTYMTQDAGIELMVTQSETSG
                     WVPEPITRICLDSAADQEMLSQESDRNPSITTTPHNMAYLIYTSGTTGNPKGVMVEHHT
                     LINMVFWHQQFFQVTEQERASQIASIAFDAAVAEIWPYLSRGASLHVCKESVRTDPAAL
                     QNWVVEQQITIGFMPTQMAEIMIHLPWPSHTSLRCLLTAGDMLRQSPPASLPFALINNY
                     GPTECTVVATATEVSPLQEGIPPIGGPIANTKLYVLDPYQQPVPIGVAGELYIGGAGVT
                     RGYLNRPELTEERFLPDPFSGESGAKMYRTGDAVKYQPDGNLIYVSRIDDQVKIR"
     aSModule        114..2660
                     /complete
                     /domains="nrpspksdomains_OF778_RS11540_AMP-binding.1"
                     /domains="nrpspksdomains_OF778_RS11540_PCP.1"
                     /domains="nrpspksdomains_OF778_RS11540_TD.1"
                     /final_module
                     /locus_tags="OF778_RS11540"
                     /monomer_pairings="Leu -> Leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       300..341
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_OF778_RS11540_0001"
                     /evalue="8.90E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="OF778_RS11540"
                     /protein_end="112"
                     /protein_start="98"
                     /score="18.8"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPMD"
     CDS_motif       537..596
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_OF778_RS11540_0002"
                     /evalue="9.60E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="OF778_RS11540"
                     /protein_end="197"
                     /protein_start="177"
                     /score="33.4"
                     /tool="antismash"
                     /translation="AYLIYTSGTTGNPKGVMVEH"
     CDS_motif       951..980
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_OF778_RS11540_0003"
                     /evalue="6.10E-04"
                     /label="NRPS-A_a5"
                     /locus_tag="OF778_RS11540"
                     /protein_end="325"
                     /protein_start="315"
                     /score="12.2"
                     /tool="antismash"
                     /translation="NYGPTECTVV"
     CDS_motif       1086..1175
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_OF778_RS11540_0004"
                     /evalue="1.20E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="OF778_RS11540"
                     /protein_end="390"
                     /protein_start="360"
                     /score="59.1"
                     /tool="antismash"
                     /translation="PIGVAGELYIGGAGVTRGYLNRPELTEERF"
     CDS_motif       1263..1328
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_OF778_RS11540_0005"
                     /evalue="2.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="OF778_RS11540"
                     /protein_end="441"
                     /protein_start="419"
                     /score="38.6"
                     /tool="antismash"
                     /translation="YVSRIDDQVKIRGFRIELGEIE"
     aSDomain        1614..1823
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_OF778_RS11540_PCP.1"
                     /evalue="1.30E-15"
                     /label="OF778_RS11540_PCP.1"
                     /locus_tag="OF778_RS11540"
                     /protein_end="606"
                     /protein_start="536"
                     /score="49.4"
                     /tool="antismash"
                     /translation="ERKLVQIWSSVLGMKETSIGVHDSFFDLGGHSMKIMEALAKGLTE
                     GWHVTVKDYYDLQTIQKIAQKIDHG"
     aSDomain        1920..2660
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_OF778_RS11540_TD.1"
                     /evalue="2.40E-44"
                     /label="OF778_RS11540_TD.1"
                     /locus_tag="OF778_RS11540"
                     /protein_end="885"
                     /protein_start="638"
                     /score="143.3"
                     /tool="antismash"
                     /translation="VLLTGVTGYLGIHLLAELLDGTNSRVYCLIRGSDPRNRLLEQISF
                     YFHDKFEKYKVMLSSRVVIVKGDLSEKQFGLSDAEYAQLDSTISSVIHSAALTKHFGNY
                     ADFEKANVTTLEELISFVGRNKRLHYMSTMSVSGHITFGEEQHVFTENDFYVQQNYEDN
                     VYVKSKFWAEHALFQAISNGVDAAIYRVGNLTNRHSDGQHQHNIADNAFMSRFKFMLQH
                     GVASNQFISNDIEFTPVDACSRAVV"
     misc_feature    complement(3374..3388)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.6"
                     /tool="antismash"
     gene            3515..3916
                     /locus_tag="OF778_RS11545"
     CDS             3515..3916
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005550331.1"
                     /locus_tag="OF778_RS11545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_268624576.1"
                     /transl_table=11
                     /translation="MEKIKAIKTELGEIHGRDAIFLDDIQFNYQKKEVTLIGEISGGLC
                     TESDDEEFIKYELLFKKVYYFNMVELDVSLQMFAHSYHESSSFVEIGNTKILRDIKNAR
                     GLELKQYVIYTYDEVFVIACQEFELRLKK"
     gene            4012..4428
                     /locus_tag="OF778_RS11550"
     CDS             4012..4428
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017688987.1"
                     /locus_tag="OF778_RS11550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_268624577.1"
                     /transl_table=11
                     /translation="MVNNFIELVEESDERYKCYGLKNTIRIFKQFIKDEDLDEVRINIS
                     TNTQLDSIMSNVESYINWFTECETVFRNYYENELREQVHKDWFKEIEVYSVNITFNSKE
                     DYGATITCGDNVLQDHILIVDFDREQIEAINLNG"
     gene            4601..5149
                     /locus_tag="OF778_RS11555"
     CDS             4601..5149
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OF778_RS11555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_268624578.1"
                     /transl_table=11
                     /translation="MKEEFDYKLFKKLLVSHYLKVIKEFAKTSDNKDVYVLTLVLNGYI
                     TLDWNTLSELHFKYEDAYKGQYEDRCSLEDIKFSIGDFAFEEMIDWTEEMDQLMTKHQD
                     FFSEVEDVSDDLYDYHNKQLIDCMIDVLKELEPAFIHLNRTSDFVAYVSDFNDEDDLRY
                     AKATVPSKLYQEVFGIEAG"
     gene            complement(5081..5377)
                     /locus_tag="OF778_RS11560"
     CDS             complement(5081..5377)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012415.4"
                     /locus_tag="OF778_RS11560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CAP domain-containing protein"
                     /protein_id="WP_326848321.1"
                     /transl_table=11
                     /translation="MVKAQDMYNNNYFDHNSPTHGSPCDMLKEFGITYNSAGENIAKGQ
                     NTHSQVMKDWMNSPGQRPVVLHPRNPILWQISPSFYSKYFLIKFGRNGRFCIS"
     gene            complement(5546..5716)
                     /locus_tag="OF778_RS11565"
     CDS             complement(5546..5716)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OF778_RS11565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_268624579.1"
                     /transl_table=11
                     /translation="MEKFFVLAILLLVTGCLSHNNMMQKQVTPKQKQISTHDHAANTGW
                     KSSKPVTHRKY"
     gene            6029..6448
                     /locus_tag="OF778_RS11570"
     CDS             6029..6448
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OF778_RS11570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_268624580.1"
                     /transl_table=11
                     /translation="MYGVVANVVIDKQLRNGAKVYILYCHGMARSPKVFGMARGGERIE
                     KYISYKKLNKFRAQWLPEHIRSKVVWKYVDRRDAERFAKSLELKWTNVRLLDEEGNIIR
                     EGIPESEADNIVSNIRFIKKEFVFSQESIDNNNNS"
     gene            6583..6678
                     /locus_tag="OF778_RS11575"
     CDS             6583..6678
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639195.1"
                     /locus_tag="OF778_RS11575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative holin-like toxin"
                     /protein_id="WP_021260480.1"
                     /transl_table=11
                     /translation="MEVKDAITIMLLFGSFILALLTYINHNNKRK"
     gene            6979..7287
                     /locus_tag="OF778_RS11580"
     CDS             6979..7287
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007132454.1"
                     /locus_tag="OF778_RS11580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_268624581.1"
                     /transl_table=11
                     /translation="MKVITLCGSTKFKEQFEQANRYLTLQGNIVISLAFFEQSEGIEIT
                     TEQAELFTKIHLRKIEMSDEIFVIDVDGYIGSSTKNEIEYAIEKGKTIRYFSKSELV"
     gene            7683..9077
                     /locus_tag="OF778_RS11585"
     CDS             7683..9077
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /GO_process="GO:0009410 - response to xenobiotic stimulus
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005550327.1"
                     /locus_tag="OF778_RS11585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MATE family efflux transporter"
                     /protein_id="WP_065294092.1"
                     /transl_table=11
                     /translation="MSTIVPSIKRRTTFLLNKYFTGETLDYKQIIAIIIPIFVDQAFII
                     LMSLLNTAMISSSGVAAVSAVSMVDSLNIFLVNVFVAVATGGTVIVAQYKGRGNADMVS
                     KSAAQAISAVALLSILISAVVIIFHNPTLDLLFGRAEADVLDNARIFLIGSCLTYPFIA
                     IFQAVTGALRGVAETKACLGLSFIMNLTYLFLNILFITVLDMGVVGLIISMLTARVLGM
                     VISLIYLLKINQTLQFRIQNALKLDFSILKKIMIIGVPFAAEQMFFNGGKLLTQTFIVQ
                     LGTLAITVNAISGSISLVFQIGANALSIAIVTVVGQCIGRRNIEDARKFIKSFLWLSSI
                     IFVIAAVILMPLFPWIVRLFSPPAEIIPEIFKLTVLIAITQPFLWSISFIMPSALRAAG
                     DSNFTSITAMLTMWLFRVILGYVLGIPLGLGIMGVWIAMVIEWGIRGSVFLWRFRGEKW
                     YSRKLI"
     gene            complement(9184..10065)
                     /locus_tag="OF778_RS11590"
     CDS             complement(9184..10065)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /locus_tag="OF778_RS11590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS3 family transposase"
                     /protein_id="WP_268624582.1"
                     /transl_table=11
                     /translation="MFGNLGAGGTTQKYRAIKEAAVEYNVRDLCKVFGVSRSGYYAFLK
                     RHEVDHDKPLKDLIQNYQKYDGKYGYRQIQLFLLQDHGVWVNHKRVLRLMQTMNLRSKI
                     RRKRRCNYSSSTGGRVVENLLQRQFQAEVPNQKWVTDVTQYRVEDKWLYLSAIKDLFNN
                     EIVAYQMSLHNDNQLVLQTFEKAFNKTKDVTGLIVHSDQGFQYTSYAYHDMLPKVGAQI
                     SMSRKGNCYDNASMESFFSHLKTEGLYPYHIRSLDEAQRRIEEYIHFYNHNRPQRKLKK
                     LPPVEYRRQLAA"
     gene            complement(10014..10331)
                     /locus_tag="OF778_RS11595"
     CDS             complement(10014..10331)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /locus_tag="OF778_RS11595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_232055641.1"
                     /transl_table=11
                     /translation="MAIKGQKFKTYSEELKAEAIRLHVEEKWTYRQINEHFGIHDKQRM
                     KKWMRKYREKGEFGLLDQRGRRQQYIDQDRYLNQLKRENEMLKKCLEIWVQEVRLKSIE
                     R"
     gene            10666..11172
                     /locus_tag="OF778_RS11600"
     CDS             10666..11172
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005550325.1"
                     /locus_tag="OF778_RS11600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DinB family protein"
                     /protein_id="WP_268624583.1"
                     /transl_table=11
                     /translation="MELEEIKQNLKETRDKLFGILKGLNGDQLNERKDEDSWSIGQICQ
                     HLAKVEEIYVVAIKRGLQNTEESSVEHKSIDSLLDRKIKLAAPDIVKPTDERYEYEDII
                     ATLNNSRQQFVEMLNALEDPSILSRRHFVHPAFKEMLLIDWVKSTYVHEERHIQQIQEI
                     LNGVR"
     gene            11343..12941
                     /locus_tag="OF778_RS11605"
     CDS             11343..12941
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005550324.1"
                     /locus_tag="OF778_RS11605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator"
                     /protein_id="WP_268624584.1"
                     /transl_table=11
                     /translation="MYKLILVDDEEDVREGVLHEMDWESFGFTVVETAENGQEAMEYIE
                     RLQPDIVVTDIHMPFMNGLQLAEWIRSHDPSMKIMILTGYDEFEYAQKAIKLHIDEYVL
                     KPFSAAELQAALVKVKQQMDQEVAEKNNLLTLQDHYRKSLPVLQHVFLSSLLTGKCSLE
                     DIHEKCERYEMDLSGSAYLVSAIQMDHSKEEKNRYLLQFAICNIAEELVLKHMPGRVFI
                     HHDHVIVLTMSASREGDRMSQETIGIVEEILQSVHRFLKITVTIGVGTVVNDLSELASS
                     YQEAVQALHYRLIHGNHRVIWIEDVEAKRVNPLVFDDMKEQALIRCMKVGTIEEAQAMM
                     GEFFDVVESCTVSLQDFQIYWIEIWTAMMKVAKDMDVNYEQFLGGAVHPLMEIYHCNNA
                     SEAKNWMLHQCMKIMNCIAVERQTGYKKLVDDAKAYMKLHYADLDISIHTVCRHLHIST
                     GYFSHIFKKEAKTTFVSYLLELRMEAAKELLRSTDLKAFEIGEKVGYADPNYFSFSFRK
                     RFGLSPKEYRNRDRG"
     gene            12949..14691
                     /locus_tag="OF778_RS11610"
     CDS             12949..14691
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005550323.1"
                     /locus_tag="OF778_RS11610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_268624585.1"
                     /transl_table=11
                     /translation="MINVRSIQFIIAKTFIFITVAAVCMVSIMLYNKFSSTAETNADLN
                     IQQVVEQVNYNLEIYVNNITSIFDVVQDLIRRSPSVTNPILIEQLKSIMKTREDLISIA
                     LFTKQGKLVFNTPQLTMRSNTQLERQSWFEAAMARPDQLSFSSPHIQNLFKTTYKWAVS
                     ISKQAGYRTGVGQHDQGVLVIDMNFKTINELSKQVSFGKRGYIYIIDSFGNIVYHPQQQ
                     LIYAGLKYENLERVLTYAYGSFQDNSNDESKLITVKTVNPIGWKVVGVAYKDEIVTTKS
                     ELNTFILWFLVIVILIVLFVSIVVSARISLPIQNLAKSVKSAGEGDFTVPISTMGIYEV
                     DQLSSRFNMMLRQIRQLMDQIIVEQEAKRKSELDVLQAQINPHFLYNTLNSVIRLAERG
                     ETREAVTAITSLSRFFRISLSKGKNIITVQEEIEHVRHYLIIQTIRYKRKFQYAIDIQD
                     EALDCMTMKLILQPIVENAIVHGIEMKQEEGMITITAAIVEDKLMLQVTDNGLGMSPQT
                     VNSLLTKKVRSESGSGVGVKNVHDRIQLCFGQGYGLEFESELEEGTTVKIWLPIVRDER
                     EEES"
     gene            14688..15659
                     /locus_tag="OF778_RS11615"
     CDS             14688..15659
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005550322.1"
                     /locus_tag="OF778_RS11615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_268624586.1"
                     /transl_table=11
                     /translation="MNRRMNLLLIVILSLSFSLSSCSIQTNMMSDNMLAIDLIVKMNQG
                     DYWNTLKSGAEAAAKEFNVKLQFLAPNHEDDIPGQIELVNQSIQNRPDAIILAASDYMG
                     LAQATDRIAYQNIPIISIDSEVGSARVKTYVGTNNYEAGQLAAKRMIELIHESGQIAVM
                     NFVEAAKNANQREEGFQDYVARFPNVRVVDIQYSQSNQRNAEEITRRWLAQYPSLDGIV
                     ALNAESSIGVGREVQRSGHGGRVKVIAFDSPPETMGLLQDGVVQALVLQNPFNNGYLAV
                     KYAVDIIEGRNVPERIDTGVKLIDLDNMLWPENQKLLFPFVK"
     gene            15796..16824
                     /locus_tag="OF778_RS11620"
     CDS             15796..16824
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017249788.1"
                     /locus_tag="OF778_RS11620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="galactose ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_174808952.1"
                     /transl_table=11
                     /translation="MKKVSALILASALIATVVSGCANGKSSGGDGGSEPLVGVAIYKFD
                     DTFMTGVRNAISDSAKGIAQADIVDSQNSQPTQNDKVDLFITKGVKALVVNPVDRTAAG
                     VIIDKAMAKDIPVVFLNREPLPEDMKKWDKVYYVGAKAEESGTMSGQLIADYWKSHPDA
                     DKNKDGVLQYVMLKGEPGHQDAELRTKYSIQAIEDAGIKVEKLQEDTGMWDRVKGQEKM
                     AAFLAAHGDKIEAVFANNDDMALGAIEALKANGYFKDNKFIPVVGVDATAPALQALEEG
                     TLLGTVLNDAKNQGKAAITLASVLAKGEKPTKENVGYEITDNHYIWISYKKITKDNMAD
                     AK"
     gene            16921..18432
                     /locus_tag="OF778_RS11625"
     CDS             16921..18432
                     /EC_number="7.5.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018758272.1"
                     /locus_tag="OF778_RS11625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="WP_268624587.1"
                     /transl_table=11
                     /translation="MGQHEFVLEMNNISKEFPGVKALDQVTLQVRPGTVHALMGENGAG
                     KSTLMKCLFGIYTPDEGEIMVNGEAVQIPNSKTALNIGISMIHQELHPVPYRNVMENIW
                     LGRFPTRGIGPIQFIDHKRMARDTRDLFKQLDIELQPETMVHTLSVSKIQSIEIAKAVS
                     FHSRIIVMDEPTSSLTDVEVEQLFRIIRELKKNGVAIIYISHKMEEILQISDEVTIMRD
                     GKKIGTWPASELTTDLIISRMVGRDLTNRFPPRNNVPGEVVMRVQGLTSPLPKSFNHVS
                     FDLHRGEIVGIGGLVGAQRTELMEALFGLRDIQSGTISIQGKEVRIDSPVIAKKHGMAL
                     LTEERRVTGIFPVLSVHENAAIANLDHYRKPYFLLDGKKKKAEVDAMVQKLRTKTPSTR
                     ELIMNLSGGNQQKVLFARWLLTEPDILLLDEPTRGIDVGAKYEIYSIIAELALQGKSII
                     MISSEMPELIGMSDRIMVMSEGRLTGILNGKEATEEEIMRLAAQH"
     misc_feature    16949..16963
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.28"
                     /tool="antismash"
     gene            18458..19468
                     /gene="mglC"
                     /locus_tag="OF778_RS11630"
     CDS             18458..19468
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mglC"
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015735909.1"
                     /locus_tag="OF778_RS11630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="galactose/methyl galactoside ABC transporter
                     permease MglC"
                     /protein_id="WP_268624588.1"
                     /transl_table=11
                     /translation="MNAKRIQSFISQNVIYMVLAVLIIGIAIYDPSFIGLNPLRDILNQ
                     SSTRVIIALGVAFVLITGGTDLSAGRIVGLSAVVSASMLQTTDYARRFFPDLEELPLFV
                     PILLAVVVGLIFGLINGIIVAKFKVPPFIATLGTMVAVYGVNSLYFDTAPNHSQPIGGL
                     RPDFKEYFGTGSIGYGGVSIPIIVVIAIAVAFIVWVVFNKTRLGKNMYAIGGNQQAARV
                     SGINVGRNLVYIYAIAGALYGLAGVLEAARTGGATNNYGNMYELDAIAACVVGGVSTTG
                     GIGTVPGVVTGVLIFTVINYGLTFIGVSPYWQLIIKGSIIVAAVAFDMRKYAAKK"
     gene            19578..19973
                     /locus_tag="OF778_RS11635"
     CDS             19578..19973
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018759008.1"
                     /locus_tag="OF778_RS11635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_268624589.1"
                     /transl_table=11
                     /translation="MKAACFHYVLHFFEGGQIMMQLNLSAIICSFLVGLSLVVSSVIIS
                     QSSDREVMKYGSRHKPLLTIEEAAEYLHIPESKVRAIISSEELMLRNGVDTSRLLFPIV
                     RIGTDNFISTDGLQEWLKEPLKHRLQY"
     gene            20162..20656
                     /locus_tag="OF778_RS11640"
     CDS             20162..20656
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019420797.1"
                     /locus_tag="OF778_RS11640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_268624590.1"
                     /transl_table=11
                     /translation="MKVWVKRQDPNNKYGAKFTLGNRDVELPETAIISVTRGERFNITR
                     MIINGIVNEIVKKQLTKNENLLYAELSGQLQGGIGQTVTVWKDASSMNYFRTNGAHKFA
                     KKFFSWVFYSGEVRAYFLTWKTGNRIPLDIEIEGIIKKYGKYFDGGKLIRHAQQPPDNS
                     R"
     gene            20701..21327
                     /locus_tag="OF778_RS11645"
     CDS             20701..21327
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005550305.1"
                     /locus_tag="OF778_RS11645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2185 domain-containing protein"
                     /protein_id="WP_268624591.1"
                     /transl_table=11
                     /translation="MTWSLDSVVERHKEAPYTFYVPSEYVLSKIEIGELVKLIFLCGEE
                     DAEYCGERMWVEIIHRSGDELIGTLRNEPVSIKDLVFGQEIHFKIEHICDTMHHDPSAV
                     NWDYYFEKKVVVTNDVLERNEFNFMVRDFPNEGSESDTGWSFFTGYEEENDPDDINNNQ
                     FISIGKVLNIDDSILSFIDREPQCAFERNLETKEFYEVFDYEWEE"
     gene            21404..21850
                     /locus_tag="OF778_RS11650"
     CDS             21404..21850
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017814760.1"
                     /locus_tag="OF778_RS11650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="oxidoreductase"
                     /protein_id="WP_268624592.1"
                     /transl_table=11
                     /translation="MEKINFLETKPATRFDELDPNQDGNKNTRFADLIIDGRSIYQMFK
                     KHDLVSPLGWGSEENQKLMIDYFLLREQHEYMYNRYPILVCPWCGDEDCGFISVFIERE
                     GDIVIWKDFMKDHENKTIPFGPFYFKWDNYKQVIDSTFGTAGIQ"
     misc_feature    21961..21974
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.07"
                     /tool="antismash"
     misc_feature    21983..21997
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.36"
                     /tool="antismash"
     gene            22340..22663
                     /locus_tag="OF778_RS11655"
     CDS             22340..22663
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /locus_tag="OF778_RS11655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS30 family transposase"
                     /protein_id="WP_268624874.1"
                     /transl_table=11
                     /translation="MVASQYPQAALQTTTVDRGKEFACYASLENFHNLEVYFADPYSSW
                     QRSSNENGNGILREFFPKGHDFASVTDEDLARAICLINNRPRKCLGWMSAYEAFMDDLS
                     HLA"
     gene            complement(<22668..22859)
                     /locus_tag="OF778_RS11660"
                     /pseudo=""
     CDS             complement(<22668..22859)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002011403.1"
                     /locus_tag="OF778_RS11660"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKESLVKYMAKYTSLTKVEQRIFLESIHLEEYKKGTVLLRQGDVP
                     TNCYFVLQGRVRQFLIHES"
     misc_feature    complement(22972..22987)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.34"
                     /tool="antismash"
ORIGIN
        1 gatcgatagg ccagatgcag ttgattagcg aagcagaaac gaagcagcaa ctggagatat
       61 ggaaccggac ggagacggcg tatccacggg atccggtaat tcaggagctg ttcgaggagc
      121 aggcggcagc acggccggaa gcggtggcag tcgttgacga agaccgccag ctgacgtatg
      181 gggaactgaa tgcgcgggct aaccaactgg cgcactactt gcggaagaaa ggcgtgaagc
      241 cggagacgct ggttgggatc tgcatggaac gctcggcgga cctgatcgtc gggatcctgg
      301 ggatcttaaa agctggtggc gcgtatgtgc cgatggatcc gtcgtatccg cagcagcgct
      361 tgacttacat gacccaggat gcgggaattg agttgatggt gacccagagt gagacaagcg
      421 gttgggtgcc ggagccgatc acgcgcatct gtctggacag cgctgccgat caggagatgc
      481 tgtcacagga gagcgaccgg aatccgtcaa tcaccacgac gccgcacaac atggcctatc
      541 tgatttacac ctcaggaact acagggaatc cgaaaggggt tatggtcgaa catcacacac
      601 tgatcaatat ggtgttctgg caccagcaat ttttccaagt tacggagcaa gaacgtgcga
      661 gtcaaatagc aagcatcgca tttgatgccg cagtggcaga aatatggccc tatctgagca
      721 gaggcgctag tttgcatgtg tgcaaggaaa gcgtaagaac ggatcctgca gcgttgcaga
      781 attgggtcgt tgaacagcaa attacgatcg gttttatgcc aacgcagatg gccgaaatca
      841 tgattcatct gccttggccg tcgcatacat cgttacgctg tttgctgacg gcgggggata
      901 tgctgcggca gtcgccgcca gcttcattgc cttttgcact catcaacaac tacggcccta
      961 cagagtgtac agtcgtggct acagcaacag aggtcagccc cttgcaggag ggcataccgc
     1021 caattggagg accaatagcg aatacgaagt tatacgtgtt ggatccatat caacaacctg
     1081 taccaatcgg tgtcgctggg gagctgtaca ttggcggggc aggggtcact cgtggatact
     1141 tgaatcgtcc agagctgaca gaggagcgat tccttccgga tcctttcagc ggtgagtctg
     1201 gagcgaaaat gtacagaacg ggagatgctg ttaagtatca gccggacggc aacctgatct
     1261 atgtaagcag gatcgacgac caagtgaaaa tcagaggatt ccgtattgag ctcggagaga
     1321 ttgaaatggt gttaagtcag ttgccggcga tcaagcaagc tgtcgtcatc gtgcgggaag
     1381 ataggccggg ggaaaagcaa ctggcggcgt atctggtcgg agaaggcagc gcacaggaat
     1441 ggcggacata cttgagcgag cgcttgccaa gctatatggt gccgacgtat tttgtgcaac
     1501 tggacagttt gccgttaacg ccgaacggga aaatcgatac gaaatctctc ccgaaaatcg
     1561 acagtgtact gcaaacatct gcaagttata tcgcgcctcg tcatgcaaca gagagaaaac
     1621 ttgtacagat ttggtcaagc gtgttaggga tgaaggaaac ttcaattggc gtccacgatt
     1681 ccttctttga cttaggcggg cactccatga aaattatgga ggcattggca aaagggctga
     1741 cagaaggatg gcatgtaacg gttaaggatt actacgatct gcaaaccata caaaaaatcg
     1801 cgcaaaagat tgaccatggt tcaaaaaaat acttgcattc cgatacatct aggctgcaat
     1861 ttctcaagcc tccgaagaaa gacatcgctc atgcaaccta cgaccctatc ggtaatgtat
     1921 tgcttacagg ggtcacgggt tacctgggca tacatttact tgcggagctg ctggatggaa
     1981 ccaatagcag agtatactgt ttgattcggg gaagtgaccc acggaatcgg ttgttggaac
     2041 agatttcctt ttactttcat gacaagtttg aaaagtataa agttatgcta agcagccggg
     2101 ttgttatcgt aaagggtgat ttgtctgaga aacaattcgg cctaagcgat gctgaatatg
     2161 ctcaacttga cagtacgatc agtagtgtca ttcattctgc cgcgttgacc aaacacttcg
     2221 gtaattacgc tgattttgaa aaagcgaatg taacaacgct ggaagagctt atatcgttcg
     2281 taggacgtaa taaaagactg cattatatgt ccacgatgag cgtatcaggt catattacat
     2341 ttggggaaga gcagcatgta tttaccgaaa atgattttta cgttcaacaa aattatgagg
     2401 ataatgtgta tgtgaaaagt aaattttggg cggaacatgc actgttccaa gcgatctcga
     2461 atggggtgga cgctgccatt taccgggtgg gcaatctgac caaccggcac agtgatgggc
     2521 aacatcaaca taatatcgca gacaatgcat ttatgagccg cttcaaattt atgttgcaac
     2581 atggggttgc ctcgaaccaa ttcatatcta atgatataga gtttactcct gttgatgcgt
     2641 gcagcagagc cgtcgttgcc ttaataaaag cagatgcaag cgctggggaa aactacgttt
     2701 tccatgtgta caatcatcac aaagttggac ttggcgaggt cgtgcaattg ctacacaagt
     2761 ctgggcatga gattgctttg ttagatggtg tggcgttcca ggatcttatg cttcgattat
     2821 ctcaggatga taagcacatt catgacattc aaatgttaat ggcagcagga gaacagcttg
     2881 aaggcgatta tgccattgtc aagcatgatt cgttacaaac acaaatcgcc ttaagcaagg
     2941 ccggatttta ttggccgaaa attgatgcac tgtatatgca aaaaatcgtg acctacttgc
     3001 aaaattccgg atacttacca gtgaatgaga tgagaagctt gatccagcac gtgtagtgct
     3061 atggctgtgt aacttgggtt cgatctcata tgattccagg attgacatgc taactgagca
     3121 tatatgtaac cttgcagcag ctcccttgtg attggagcct tcctaaactc tcgtcaagta
     3181 gacatcacta aagaagcagc ctttaagcaa ccttagttcg gtattgaacc ggactaaggt
     3241 tgtttagtct ctttggaaag cgctcgttgt tatagaactc ataaaacctc tatcatttac
     3301 gtatggctta ttgtcttttc catataaatg cttacaatag gtcttgtacc atttgttatt
     3361 tcgaggaaca ttttgtaaac gaaattcatc taagggaaaa ataaaaatga aaataacatt
     3421 tcgaattaga cttctatgat cgagaactct ggaaaagatg aaaatcgcct aaaaactatc
     3481 tacgctacgc atcgggctag aaaggttgaa agagatggaa aaaatcaaag ctataaaaac
     3541 cgaattgggt gaaattcatg gaagagacgc gattttcctt gatgatattc aattcaatta
     3601 tcaaaagaaa gaagttacat taattggcga gataagcgga ggattatgta cagaatcaga
     3661 tgatgaagag tttattaaat acgaattgct attcaagaaa gtttattact ttaatatggt
     3721 tgagttagat gtaagtttac agatgtttgc tcattcatat catgaaagta gtagcttcgt
     3781 agaaataggt aatacaaaaa tacttagaga tataaagaat gcacgaggtc tggagttaaa
     3841 gcaatatgta atatatacat atgacgaggt tttcgttatc gcatgtcaag aatttgaatt
     3901 acgtttaaag aaataagagc tttaagcaac aatttagatt cagagaagcc gagttgtact
     3961 ttcattgttg ttatcaagaa agataatgct acataattga ggtgctatta aatggtgaat
     4021 aatttcattg agctggtaga agaaagtgat gagagataca aatgctatgg cttgaaaaat
     4081 acaatacgaa tatttaagca attcataaag gatgaagatt tagatgaagt gcgtatcaat
     4141 atatccacga atacgcaatt agattcaatt atgagtaatg tagagtcgta cataaattgg
     4201 tttacggagt gtgagactgt ttttcgaaac tattatgaaa acgaacttcg tgaacaggta
     4261 cataaggatt ggtttaaaga aattgaagta tatagtgtaa atataacatt taatagcaaa
     4321 gaggattacg gagcaacaat aacttgcgga gacaatgtat tacaagatca catattgata
     4381 gttgattttg acagagaaca aatcgaagca atcaacttaa atggataagg tctaggtagg
     4441 tcaagaataa ttagcagcga attgatgatg cgtgatattt tcagatttga tatactatca
     4501 agctctaact ctggaagaga tcatagaaga aggattgaaa tataaaacaa taatattgtg
     4561 agggtacggc aactcagacg tgagataaag gagagtttaa atgaaagaag aatttgatta
     4621 taagttattt aagaaactat tagtatcaca ttatctgaag gtaataaaag agtttgcaaa
     4681 aacaagtgat aataaggatg tatacgtcct aacattagtt ttaaatgggt atataacatt
     4741 agattggaac acgttatcag aactgcattt taaatatgag gatgcttata aaggacaata
     4801 tgaagataga tgttcactgg aggatataaa gttcagcata ggtgattttg catttgagga
     4861 aatgattgac tggacagaag aaatggatca actgatgaca aaacatcagg attttttctc
     4921 ggaagtggag gatgtttctg atgacttgta cgattatcac aataagcaac taattgattg
     4981 tatgattgac gtattgaaag agttggaacc agcatttatt catctgaatc gaacaagtga
     5041 ttttgttgct tatgtatccg attttaatga tgaggatgac ttaagatatg caaaagcgac
     5101 cgttccttcc aaactttatc aagaagtatt tggaatagaa gctgggtgat atttgccata
     5161 gaatcggatt tcgaggatgc aatacaacag gtctttggcc ggggctattc atccaatcct
     5221 tcataacttg ggaatgggtg ttttgccctt ttgcgatatt ttctccagca gaattgtatg
     5281 tgatcccgaa ttccttcaac atatcgcagg gtgatccatg tgttggagaa ttatgatcaa
     5341 agtaattgtt gttgtacatg tcctgtgcct taaccatagc cacatttgac aattcctctc
     5401 tcctacccaa ggaactaatc ctgttttgga tctttcctga tttactagat ccagaacctg
     5461 ctgctcgaat tcggataaat tattatcgac agtatcattt ttactttccc ctgttggttc
     5521 tgttgaacct gtcggatccc ttttttcaat atttcctgtg ggttactggt ttgctggatt
     5581 tccagccggt gttcgcagca tgatcatgag ttgaaatttg tttttgctta ggagtcactt
     5641 gcttttgcat catattgtta tgggacaaac agcctgtcac caataataag attgctagaa
     5701 cgaaaaactt ttccatttgc caacctccta gatccggtaa ttaatgaagt taccggattt
     5761 aggttttcct gtacgccctt tacttatttc tcagtatgat tttctcctta tccagagtac
     5821 ctttttgtga tcaatagcac ttagataatt ttgtgtctct aggaaagcaa agtgtgttgt
     5881 cgaatggtta tggataagga aggtctcggg ttatatattc atcacgagat acatgttata
     5941 tatttcatta ggattcctaa cgtaataaaa agatatcata aatgatgact gtgggacgaa
     6001 gactttgcag ggagggagaa tcacaatcat gtatggagtt gttgcgaatg ttgtgataga
     6061 taagcaactt agaaatggag cgaaagtgta tatactgtat tgtcatggga tggcaaggag
     6121 ccctaaagta ttcggcatgg caagaggtgg tgagagaatt gaaaaatata tttcatataa
     6181 gaaactaaat aaatttagag cacaatggct ccccgaacat attagatcga aagtggtttg
     6241 gaaatatgtt gatagaagag atgctgaacg attcgctaaa tcgttggagt tgaagtggac
     6301 taatgttcgt ttacttgacg aagaaggaaa tattattaga gaaggtatac cagaaagtga
     6361 agcagataat atagtaagta atataaggtt tattaagaag gaatttgtat tcagccaaga
     6421 aagtattgat aacaataata attcataggt ttctcgagga acgcgttttc atgatactaa
     6481 aaacaagata agaacacttg tacgcaggtg tgaataaagg taaaatataa ctacaattga
     6541 atcttgggtg ggcatggttt cccttcgaaa ggaggtgagg ccatggaagt aaaagatgca
     6601 ataacgatca tgctcctttt tggatcgttc attcttgctc ttttaacata cattaatcat
     6661 aacaacaaga gaaagtaaaa aacccacccc aaggttgcag ccaaaggtgg gtttatctcc
     6721 gtattgacta agaagggatt acccatccaa gccaattgta ttgaccaagt gttcgcagca
     6781 cttggtcttt attacatata tagtaccata atcgaaaaga tgtatcaaag gtctgaattg
     6841 ttgaaatgtt gaaatgttga aatagacaaa agacatagtc atcattatcg atatattcac
     6901 ctccttttct ccataaagcc tcttgggtat aagatgcaac aagtaatgag aaatcagcgg
     6961 aaagaagagg ggacatagat gaaggtaatt acactttgtg gctctacaaa atttaaagaa
     7021 caatttgaac aagccaatag atacttaacg cttcaaggga atatagttat tagtttggcg
     7081 tttttcgagc aaagcgaagg aattgagatt actacggaac aagcagaatt gtttacaaaa
     7141 atacatctcc gtaaaataga aatgtcggac gaaatatttg ttatcgatgt tgacggttat
     7201 atcggtagta gtacaaaaaa tgaaattgag tatgctattg aaaaagggaa aacgattaga
     7261 tacttttcta aaagcgaatt ggtataacac gattttcctt aagctcaact tttcgctaag
     7321 aagtgaatgt gctttcggaa tattcccttg gaaatagcat gcgatgcaat gactgggtga
     7381 ccggcgatta gaaccccttg ggacagtata aaaggaactt ttgggtagga gtgatctcgg
     7441 aatcaaccat aaagtatgtt tcattatgat tggacatgat gtgtaggcga gtatgaagcc
     7501 gtatctctgc catatgtata taaaaagact gcaaaagcga gtgcggtgct cggaaaccac
     7561 gaaatatgcg taaataagga cacacacctc actttcatct cctctaaaga gtggtataat
     7621 agtgcgtcac tatgtgaggt caaggggatc ctcggcacaa tacacgaaga agagatgata
     7681 cggtgagtac aattgttccc agtataaaga gaagaacgac cttcctgttg aataaatatt
     7741 ttacaggaga aacgcttgat tataagcaaa ttatcgcgat tattattccg atatttgtgg
     7801 atcaagcttt tattattttg atgagcctgc tgaatacggc catgatcagc tcctcggggg
     7861 tagcggcggt tagtgcggtc agcatggtgg attcgttgaa catcttcttg gtcaacgtgt
     7921 ttgtagctgt ggcgacgggg ggaaccgtca tcgtcgcaca gtataaaggc aggggcaatg
     7981 cggatatggt ttcgaagtca gctgctcaag ccatctcggc agttgcgctg ctgtcgatct
     8041 tgatcagtgc ggtcgttatt atttttcata accccacact agacttactg ttcggtcgtg
     8101 cagaagcgga tgtcctggat aatgcaagga tctttttgat cgggagctgc ctcacgtacc
     8161 cgttcattgc gatttttcaa gctgtgacgg gggcgttgcg cggcgtggca gagacgaagg
     8221 cctgcttggg tctatcgttc attatgaact tgacctacct gtttctgaat atattgttca
     8281 ttacggtact cgatatgggc gtagtcggat tgatcatttc catgcttacg gctcgtgtgc
     8341 tgggaatggt gatatcgtta atttatttgt tgaagatcaa tcagacgctg cagttccgaa
     8401 ttcagaatgc actgaaattg gatttttcga ttttgaaaaa aattatgatt atcggcgttc
     8461 cttttgcagc ggagcagatg ttctttaatg gcgggaagct gcttacacag acgtttatcg
     8521 ttcagctcgg tacgcttgcg atcacggtca atgccataag cggctccata tcgcttgtgt
     8581 tccagatcgg agcgaatgcc ttaagcatcg cgatcgtcac ggtcgtaggc caatgcatcg
     8641 gacgacgcaa tattgaggat gcgaggaagt ttatcaagtc tttcctgtgg ctgtcctcca
     8701 tcatattcgt tattgcggca gtgattctca tgcctttatt cccttggatc gtgagattgt
     8761 tctctcctcc ggcagagatc attccggaga tctttaaact tacggtgctg attgcgatta
     8821 cccagccatt cttatggtcg atcagcttta ttatgccatc ggctcttcgt gcagcgggtg
     8881 attccaactt tacttcgatt actgctatgc tcacgatgtg gttgttccgt gtcattctgg
     8941 gctatgtact cgggataccg cttggccttg gtatcatggg ggtatggatt gcaatggtca
     9001 tagagtgggg gatccgcggc tccgtcttcc tctggcgctt ccgcggggag aagtggtaca
     9061 gccggaagtt gatttgatag tttcatgagc cattacgtta gctcttaaac aaagagaaaa
     9121 gacagcgaaa tcctatttaa ggaggatggt caagacccca tttagtggac atagaaaaaa
     9181 cacctaagca gcaagctgtc gtcggtactc tactggcggc agcttcttta gctttctttg
     9241 tggtcgatta tgattataaa aatgaatata ttcttcaatt cgcctttgtg cctcgtccaa
     9301 acttcggata tgataaggat agagcccttc cgttttgaga tgcgagaaga agctctccat
     9361 agaggcatta tcgtaacaat tgcctttccg agacatgctg atttgggcgc caaccttcgg
     9421 cagcatgtca tggtaagcgt aggacgtgta ttggaaccct tgatcgctat gaacgatcaa
     9481 tccagtcacg tctttcgtct tattgaaggc tttctcaaac gtttggagaa caagttgatt
     9541 atcgttatgc aagctcatct gataagctac aatttcatta ttgaacaagt ccttgatggc
     9601 cgaaaggtat aaccatttat cttctacacg atactgagtg acatcggtta cccatttttg
     9661 attgggaacc tcggcttgaa actgccgttg tagcaagttt tcaactactc gtccacctgt
     9721 ggaagaggaa tagttacaac gacgctttcg gcggatctta gatcgtaaat tcatggtttg
     9781 cattaagcgt agaaccctct tgtggtttac ccacacacca tgatcttgaa gtaggaacag
     9841 ctggatttgt cgatatccat acttaccgtc gtacttctga taattctgaa tcaagtcttt
     9901 caatggcttg tcatgatcca cctcatgcct ctttaaaaaa gcatagtatc cacttctaga
     9961 gacaccgaaa actttgcata aatctctaac gttgtactcg actgctgctt cctttatcgc
    10021 tctatacttt tgagtcgtac ctcctgcacc cagatttcca aacacttttt tagcatttcg
    10081 ttctcccgtt ttagctgatt taggtaacgg tcttgatcga tatattgctg gcgtcttccc
    10141 cgttgatcca gaagcccaaa ttcacccttt tcacgatatt tcctcatcca tttcttcatc
    10201 ctctgtttat catgaattcc gaaatgttca ttgatctgcc gataagtcca cttttcctcg
    10261 acatgtagac gaatagcttc agcctttagt tcttctgaat atgttttgaa cttctgtcct
    10321 ttgatagcca taaaaaatgc accccctata atagattcat cggacgtaac acgaggggtg
    10381 tttatccaat gtctactata aggggtgcac ttcatgagtc acgctgtctt ttttttgctc
    10441 tcgtacactg gatgactccc ggagaggaag gaacaggagg gcattttgca gaatattcta
    10501 aatgaaatgt atttacatat gatagtagca gcccagtcat acatcagcag tttcgtttat
    10561 ccgcattgtg cagccccatc tattgtgcaa ttttacaccc acctgacaac catttcgtaa
    10621 tgttctaacc gtttcatcac aacaagtaat gaaagggagg tttctatgga actggaagaa
    10681 atcaagcaaa acttaaagga aacaagagac aaactgttcg gaattctgaa aggattaaat
    10741 ggagatcaat taaacgaacg aaaagacgag gatagttgga gtattggtca gatatgtcag
    10801 caccttgcca aggtagaaga aatatatgtc gtagccatta agagggggtt acagaataca
    10861 gaagaatcat ccgtagaaca caaatcaatc gattctttac tggacagaaa aataaagcta
    10921 gcggctccgg acattgtaaa gccaacggat gaacgttacg aatatgaaga catcattgca
    10981 acgctaaaca attctagaca acagtttgtt gagatgctaa acgcattaga ggatccatcg
    11041 atactgagta gaagacattt tgttcaccct gcttttaaag agatgttatt gattgattgg
    11101 gtgaaatcga cgtacgtaca tgaagaaagg cacattcaac aaattcaaga gattttaaat
    11161 ggggttagat aaggattggc atgcggaaga tgcggtcatt taattccgaa ctatacaggt
    11221 gaagtcaatt tactagcgaa taataatttc atacgagcaa cagccggtaa ttgaagcaaa
    11281 gttccgcttg cattcgattg ccggcttttt tttaactttt ctcataaaaa agggggatgt
    11341 ccatgtacaa attaatactc gttgatgatg aagaagatgt acgagaaggt gtgctgcatg
    11401 aaatggactg ggagtcattt gggtttacgg tcgtggagac ggcagagaat ggtcaagagg
    11461 caatggagta catagaaaga ttgcagccgg atattgtggt gaccgatatt catatgcctt
    11521 tcatgaatgg attgcagctc gcggagtgga ttcgtagtca tgatccttcg atgaaaataa
    11581 tgatattaac gggctacgat gaatttgaat atgcgcagaa ggcgatcaag ctccatatag
    11641 acgaatacgt gctcaagcca ttttccgctg cggaattgca agccgcactg gtgaaggtca
    11701 agcagcagat ggatcaggag gttgcggaga agaacaatct actaacgcta caggatcatt
    11761 atcgaaagag cttacctgta ttgcagcatg tatttttatc ttctctcctt acaggcaagt
    11821 gttcattgga ggatattcat gagaaatgcg agcgttatga gatggactta tcgggttccg
    11881 cttatttggt ctctgcgatt caaatggatc atagcaagga agagaagaac cgttatttat
    11941 tgcaatttgc aatatgcaat attgctgagg agctcgtgct gaagcatatg ccgggacggg
    12001 tatttattca ccatgatcat gtcattgtgt taacgatgag cgcaagccga gagggagata
    12061 ggatgagtca ggagacgatc gggatcgtag aagaaattct tcagagtgtc catcgatttc
    12121 tcaaaataac ggtaacgatt ggcgtgggaa ccgtcgtgaa cgacctgtcc gagttggcat
    12181 cttcttatca ggaagcggta caagcactgc attatcgatt gattcacgga aatcatcgcg
    12241 tcatctggat tgaagatgta gaggcgaagc gggtgaatcc acttgtattc gacgacatga
    12301 aggagcaggc cttaatccgc tgtatgaagg tagggacgat agaagaagcg caagcgatga
    12361 tgggcgagtt ttttgatgtc gtggaatcct gcacggtttc gctgcaagat tttcaaatct
    12421 attggattga aatttggaca gccatgatga aagtggcgaa agatatggac gtcaactacg
    12481 agcagttcct cgggggtgcc gtacatccat tgatggaaat ctatcattgc aataatgcgt
    12541 cagaggcaaa gaattggatg cttcatcaat gtatgaaaat tatgaattgc atcgccgtcg
    12601 agcggcagac tggctacaag aagctggtgg atgacgcaaa agcgtatatg aagcttcatt
    12661 atgcggatct ggatatttcg attcatacgg tgtgcaggca tttgcacatc agcacaggct
    12721 acttcagcca tatttttaag aaggaagcca aaaccacctt cgtgagctat ctactagagc
    12781 taagaatgga agcggcgaag gaactgctgc ggtcaacgga tctcaaagcg ttcgagatcg
    12841 gtgagaaggt cgggtatgcg gatccgaatt atttcagctt cagcttccgt aagcgcttcg
    12901 gattgtcgcc caaggaatac cgcaatcggg atcgagggtg aaggtggcat gatcaacgtc
    12961 aggagcattc agtttattat cgcaaaaaca tttatattca taaccgttgc ggcggtgtgt
    13021 atggtcagca tcatgctgta taacaaattt tccagtacgg cggagacaaa tgcggacttg
    13081 aatattcagc aggtcgtaga gcaggtcaat tataatttgg agatatatgt gaacaacatt
    13141 acaagtatct tcgacgtcgt tcaggacctg attcgtagga gtccttccgt gacgaatcct
    13201 atattaatag agcagctgaa atccattatg aaaacaagag aagatttgat ttcgatcgcc
    13261 ttgtttacca agcaaggaaa gctggtcttc aacactcctc aactgaccat gcggagcaat
    13321 acacaattag agcggcaaag ctggttcgag gccgctatgg cgcgcccaga tcaattatcg
    13381 ttctcctctc ctcatattca gaatttattt aaaaccactt acaaatgggc cgtctccatc
    13441 agtaagcaag ctgggtatcg tacaggggta gggcagcatg atcagggtgt gctggttatc
    13501 gatatgaact tcaagacgat caatgaatta agcaagcaag tatcctttgg caagaggggc
    13561 tatatctaca ttatcgattc gttcggcaac atcgtctacc atccgcagca gcaactgatt
    13621 tatgcaggat taaagtatga gaacttagaa cgcgtcctta cctacgcata tggaagcttc
    13681 caagataaca gcaatgacga gagcaagctg attaccgtca aaacggtaaa tccgatcggc
    13741 tggaaagttg taggcgtcgc ctacaaagat gagatcgtaa caaccaagtc tgaactaaat
    13801 acctttatac tgtggtttct cgtcatcgtc attctgatcg ttctattcgt gtcgatcgtt
    13861 gtatctgcga gaatctcact gcccattcag aatctagcga aatcggtaaa gagcgcgggg
    13921 gaaggggact ttacagtacc gatctcgacg atgggcatct atgaagtgga tcaattgtcc
    13981 agccggttca acatgatgct tcggcaaatt cggcagctaa tggatcagat tattgtggag
    14041 caagaggcga agcgcaagag tgagcttgat gtgctgcaag cacagatcaa tccacacttc
    14101 ctatacaaca ccttgaattc ggtcatccgg cttgcggaac ggggagaaac aagggaggcc
    14161 gttacggcaa ttacatcctt atcgcgattt tttcggatta gcttgagtaa agggaagaac
    14221 atcatcaccg tacaagaaga gattgaacat gtcagacatt acttaatcat tcagaccatc
    14281 cgttataaac gcaaatttca atatgcaata gatatccagg atgaggcatt ggattgcatg
    14341 accatgaagc ttattttgca gccaatcgtc gaaaatgcga tcgtgcatgg gattgagatg
    14401 aagcaggagg aagggatgat caccataaca gccgctattg tagaagataa gttgatgctg
    14461 caagtaacgg ataacggctt aggcatgagt cctcagactg tgaacagtct tctaacgaag
    14521 aaggtaagaa gtgaaagtgg gtcaggcgtt ggcgtgaaaa atgtacatga tcgtattcag
    14581 ctatgcttcg gtcaaggcta cggactggag ttcgagagcg agctggaaga aggcacaacg
    14641 gtcaaaatct ggcttcccat tgtccgggat gaaagggagg aagagtcgtg aatcgtagaa
    14701 tgaatctatt gttaatcgtg attttgtcac tctccttctc gctgtcgtct tgttccattc
    14761 agaccaatat gatgtcggat aatatgctcg ctatagacct aatcgtcaag atgaatcagg
    14821 gcgattactg gaacacgctg aagagcgggg cagaggctgc agccaaggaa ttcaatgtga
    14881 agcttcaatt cttggctccg aatcatgaag atgatattcc aggtcagatt gaattagtga
    14941 atcaatccat tcagaaccgt ccggatgcca tcattcttgc ggcaagtgat tatatggggt
    15001 tagcacaagc gactgatcga attgcctatc agaacattcc gatcatatcc atcgactcag
    15061 aggttggatc cgcacgtgtg aagacgtatg tcggtacgaa caattatgaa gcagggcagc
    15121 tggccgcgaa gcgaatgatc gaattgattc atgaatcggg tcaaattgcg gtcatgaact
    15181 ttgtagaggc agccaaaaat gcgaatcaac gggaagaagg gtttcaagat tatgtggcca
    15241 gatttcctaa tgttcgtgta gtggatattc aatattcaca gtccaatcaa cgaaatgcgg
    15301 aggagatcac acgcagatgg ctcgcacaat atccgagtct ggatgggatt gtcgcactaa
    15361 atgcagaatc ttcaatcggc gtagggcgtg aggttcaacg atccggccat ggtggaagag
    15421 ttaaggtgat cgcattcgat agtccgcctg aaacaatggg gttgttgcag gatggagttg
    15481 ttcaggcgct ggtcttgcag aatccattta ataacggata tctcgccgtg aagtacgccg
    15541 tcgacattat tgaggggcgg aacgtacctg aaagaataga tacaggtgtt aagctaattg
    15601 atctggacaa tatgctgtgg ccagaaaacc agaagctgtt gtttccgttt gtaaaataaa
    15661 tcagcgcgca aggtgatgag aatttcgata gaactcagga ggattttcga taccggatcc
    15721 catgagaatc catcataatg aaagcgtatt cttttctagg gtattcagga atgatgttga
    15781 ggaggtcttg atcaaatgaa gaaagtatca gctttgattc tggcgagtgc attaattgcg
    15841 acagttgtta gcggctgcgc aaacgggaaa agttcaggcg gtgacggcgg cagtgaaccc
    15901 ctagtaggtg ttgcgattta taagttcgac gatacgttca tgacaggcgt acggaatgcg
    15961 atttcggatt cagcgaaagg gattgcccaa gccgatatcg tggacagtca gaattcacag
    16021 ccgacccaaa acgataaagt ggatttgttc atcacgaaag gggttaaagc cttggtcgtt
    16081 aaccctgttg accgtacggc agcgggtgtc attatcgata aggcgatggc caaagacatt
    16141 ccggttgtat tcctgaatcg cgagccatta ccggaagata tgaagaaatg ggataaagtc
    16201 tattatgtcg gtgcgaaggc ggaagaatcc ggtacgatgt ccggtcagct cattgcggat
    16261 tattggaagt cgcatccaga tgcggataag aacaaggatg gcgtattgca atatgtcatg
    16321 ttaaaagggg agcctggtca tcaggatgct gaactccgta cgaagtactc aatccaagcg
    16381 atcgaagacg cggggattaa agttgagaag ctgcaggaag ataccgggat gtgggatcgc
    16441 gtaaaagggc aggagaagat ggcggcgttc ttggctgcac atggcgataa gattgaagcc
    16501 gtctttgcga acaatgatga tatggccttg ggcgccattg aggcattgaa ggcgaatggc
    16561 tatttcaagg ataacaaatt cattcctgtg gtaggtgtag atgcgacagc accggcgctg
    16621 caggcattgg aagaaggcac attgcttgga accgttctga atgatgcaaa gaaccaagga
    16681 aaggctgcga tcacgcttgc aagcgtgctg gcgaaaggcg agaaacctac gaaggaaaat
    16741 gtcggctatg agatcacgga taatcattat atctggattt cttataagaa aattacgaaa
    16801 gacaatatgg ctgacgcgaa gtaatgtgaa ccgttgaact attggcttca agttggggag
    16861 gtagaatgat tcgttattcg tacctcctct ttttacgaag agacttaggg ggcgaaaggg
    16921 atgggacagc atgaattcgt gctcgaaatg aacaacattt ccaaggaatt tcccggagtt
    16981 aaggcgttgg atcaagtgac gctgcaagtg cggcccggaa ccgtacatgc actgatgggc
    17041 gaaaatggag cgggcaaatc aacgttaatg aaatgcctct tcgggatcta tacccctgat
    17101 gaaggcgaga ttatggtgaa tggcgaagct gtgcagattc cgaactccaa aacggcattg
    17161 aatatcggga tatcgatgat tcatcaggag cttcaccctg taccttaccg aaatgtgatg
    17221 gagaatattt ggctgggacg attcccgacg agagggattg gccctattca atttatcgat
    17281 cataagcgca tggcgcgaga tacgcgtgat ttattcaaac agctggacat cgagttgcag
    17341 cccgagacga tggttcatac gttatcggtt tccaaaatcc aatccatcga aattgccaag
    17401 gcggtatcct tccattctcg tatcattgtg atggatgaac cgacgtcatc gcttaccgat
    17461 gtcgaggttg agcagttgtt ccgaatcatt cgagagttga aaaaaaatgg cgtcgccatt
    17521 atttatatat cgcacaaaat ggaagaaatt cttcagatat cagatgaagt gacgattatg
    17581 agagatggga aaaaaatcgg gacgtggccg gcatccgaat taacaacgga cctgattatt
    17641 tctcgaatgg ttggacgcga tttgacgaac cgattcccac cacggaacaa cgtgcccggc
    17701 gaggtcgtga tgcgcgttca aggactgacc tcccctctac caaaatcgtt caaccatgtg
    17761 agttttgact tgcaccgtgg tgaaatcgtt gggatcggcg gattggtagg cgcacagcgc
    17821 actgaattga tggaggccct attcggactc cgggacatcc aatcgggaac tatctcgatt
    17881 caaggcaagg aggtacggat cgactctccc gtcattgcga agaaacatgg tatggcattg
    17941 ttaacggagg aacgacgcgt gacaggcatt ttcccggtgt tatcggttca tgagaatgcg
    18001 gcaattgcga atttggatca ctatcgcaag ccttattttc tgttagacgg gaagaagaag
    18061 aaggcagaag tggatgcgat ggttcagaaa ttgagaacca aaacaccgtc tacgcgcgaa
    18121 ctcattatga acctgtctgg cgggaaccag caaaaggtgc tgtttgcacg ctggctcctg
    18181 acggaaccgg atatattgct gttggatgag cctacccgcg gcattgacgt cggggctaaa
    18241 tatgaaattt actcgatcat tgctgaactg gccttgcagg gcaaaagcat tattatgatc
    18301 tcttcggaaa tgccggagct catcgggatg tcagatcgca ttatggtcat gtccgaaggg
    18361 cggttgactg ggattttgaa cgggaaagaa gcgacggaag aggaaattat gcggctagcg
    18421 gcacagcatt aagcagcaga gaaaggtgag atctacgatg aacgcgaagc gaattcaaag
    18481 ttttatttcc caaaatgtca tctatatggt tctggctgtt cttatcattg gaattgcgat
    18541 ttacgatcct tcatttatag gattaaatcc actccgggat atcctgaatc agtcatctac
    18601 acgggttatt atcgccctgg gcgttgcatt tgtgctcatt acaggcggta cggacttgtc
    18661 tgcaggcagg attgtgggtt tatccgcggt cgtatcggcg tccatgctgc agacaaccga
    18721 ttatgcgcgc aggtttttcc ccgatctgga ggaactgccg ttattcgtgc cgattctact
    18781 agcagtcgtt gtaggcctaa tatttggact cattaacggt ataatcgttg ctaagttcaa
    18841 ggtgcctcca tttattgcga cgttaggtac gatggtggct gtgtatggcg tcaactccct
    18901 atactttgat acggctccga atcattcgca gccgatcggc ggcttgcggc cagattttaa
    18961 agaatatttc ggtacaggaa gcatcggata tggcggtgta tccattccga ttattgtggt
    19021 gatcgcaatc gcagttgcgt ttatcgtatg ggtcgtgttc aacaaaacga gattgggcaa
    19081 aaacatgtat gcgattggcg ggaatcagca ggcagcaagg gtatcaggca ttaatgtagg
    19141 cagaaaccta gtgtatatct atgccattgc tggcgcgttg tatggcctgg ccggggttct
    19201 cgaagcggca agaaccgggg gagcgacgaa taactacgga aatatgtacg aattggatgc
    19261 gattgccgct tgcgtggtcg gcggcgtgtc aaccactggg ggcatcggaa cggttccagg
    19321 tgtagtgacg ggcgtgctta tttttacggt cattaactat ggtctgacct tcatcggcgt
    19381 aagcccgtat tggcagttga ttattaaagg atcgattatc gtagcggctg ttgccttcga
    19441 tatgcggaaa tatgcagcta agaagtaatg gtattgattt gtataggttg agacccttcc
    19501 tttatgggag ggctttttta tttgttagcc catggaaact tttgcggagg atgcaatgta
    19561 tattaagggg gaggggcatg aaagctgctt gttttcatta tgtgttacat ttttttgaag
    19621 gaggacaaat catgatgcaa ctaaatctta gtgccatcat ctgttcattc cttgtggggc
    19681 tttctcttgt tgttagcagt gtcattatta gtcaatcctc ggacagagaa gtaatgaaat
    19741 acggatccag acataaaccg ctcttgacga tcgaagaggc agctgagtat ttacatattc
    19801 ctgaatccaa agtaagagcc atcatttcaa gtgaagaatt aatgttaagg aatggtgtag
    19861 atactagtag attattattt ccgatcgtta ggattggaac cgacaatttt attagtacag
    19921 atgggttaca agaatggttg aaggagcctc taaaacatcg attgcaatat taaagaatat
    19981 gcttcgaaga aggagaaact tagatggcag cgtaaaccaa ttaagtcaaa aaatgaagaa
    20041 ttgagagaac aaccctgcga ggctaagtct gtcgggctcg gcgctttcgc tcccttaaat
    20101 cacttaggct tgtagataca agagcattag ctgaaagtcc cgattattgg aggtgttttt
    20161 ggtgaaggtt tgggtaaaac gtcaagatcc taataacaaa tatggagcaa aatttacgtt
    20221 agggaacaga gatgttgagt tgcctgaaac agccattata tcagtaacac gtggggaacg
    20281 atttaatatt acacgtatga tcattaacgg gattgtgaat gaaattgtaa agaagcagct
    20341 tacaaagaat gagaatttgt tatatgcaga gctttcaggt caacttcaag gagggatcgg
    20401 tcagaccgta actgtatgga aagatgctag ttcaatgaat tattttagaa cgaatggagc
    20461 acataaattt gcaaagaagt ttttttcatg ggtgttttat agtggtgaag ttagagcata
    20521 ttttttaaca tggaaaaccg gaaatagaat cccattagat atagaaatag aagggataat
    20581 aaagaaatat ggcaaatatt ttgacggtgg aaagcttata agacatgctc agcaaccacc
    20641 cgataattcc agatgataaa gtagatcgac tctgaaagtg caaaggagat acatataaaa
    20701 gtgacttgga gtttagatag tgttgtagaa agacataagg aagcgcccta tacgttttat
    20761 gttccgagtg agtatgtatt gagtaagatt gagattggcg agttggtcaa gctaattttt
    20821 ttatgcgggg aagaagatgc agaatattgt ggagagagaa tgtgggttga aatcatccat
    20881 cgatcaggtg atgaactgat tggaacatta cggaatgagc cggtatctat taaggatctg
    20941 gttttcggtc aagaaatcca ttttaaaatc gaacatattt gcgacacgat gcatcatgat
    21001 cctagcgctg tcaattggga ttattatttt gagaagaagg ttgttgtaac gaacgatgta
    21061 ctggagcgaa atgaatttaa ttttatggta agggactttc ctaatgaagg ctcggaatcg
    21121 gatacgggat ggagtttctt tacggggtat gaagaagaaa acgatcctga tgatatcaat
    21181 aataatcaat ttatttcgat agggaaggta ttgaatatag atgattcgat tctttctttt
    21241 atagatcggg agcctcaatg tgcctttgag agaaatcttg aaacgaaaga gttttatgag
    21301 gtatttgatt atgagtggga agaatagatg aacgctgtgc tggatatcgc acattcgatt
    21361 tatagaaaaa atggctgatg tcacagcaat gaaggagagg aatatggaaa aaattaattt
    21421 cttggaaacg aagcctgcca ctcgatttga tgaacttgat ccgaatcaag atggaaataa
    21481 gaacacccga ttcgcagact tgattattga cggaagatct atctatcaaa tgtttaaaaa
    21541 gcatgacttg gtttcacctc ttggttgggg gagtgaagaa aatcaaaaac ttatgatcga
    21601 ctattttttg ttgagagaac aacatgaata tatgtacaat aggtatccga ttttagtatg
    21661 tccctggtgt ggcgacgaag attgtggatt tatttcggta tttattgaga gagaaggaga
    21721 tatcgtaatc tggaaggatt tcatgaaaga tcatgaaaat aaaacgattc cttttgggcc
    21781 tttttacttc aaatgggata actataaaca ggtaattgac agtacgtttg gaaccgcagg
    21841 tatccagtaa ttattctgtt cgtaattcaa gactgctgtg actgcaaacc ggcttccgat
    21901 tgttagtttg ttagcactgg ctatggcggt tttcatatgc attcttacgg aatgcctgct
    21961 ggcaggtttt ttgccacaaa tggaacaaga tctggggtcg ggttgatttg catcggggga
    22021 ctatatatga agcaattcag gcccttcgtc tgcttcaaaa ccatctatcg gtggatgtac
    22081 aatggacggt tggcagccgg tgattacgac ataaaggcaa gcgtcagagg cctctggaag
    22141 atgtcggttc aaccgattag caagcgccct aaagaggttc gtaagcgtga aaccttcgat
    22201 caatgggagc tggataccat tgcctctagc cgtggcaaaa gcaaagcttg tgtagtcaat
    22261 tttattgagc gtaagacacg gcactactta gccttgaaaa tgcccgatct taccgcctat
    22321 tcgttggagg tcgcctttgg tggttgccag tcagtatcct caagctgccc ttcaaaccac
    22381 tacagtagat cgtgggaaag agtttgcttg ttatgccagc cttgagaact ttcataatct
    22441 agaagtatac tttgcagatc cgtattcttc ctggcagcga agctctaatg agaacggaaa
    22501 tggtattctt cgggaattct tccctaaagg ccatgatttt gcttcggtca ccgatgaaga
    22561 tttggctagg gctatctgtc tcattaacaa tcgtcctcgt aaatgtctag gctggatgtc
    22621 tgcttacgaa gctttcatgg atgacctgtc gcacttagct tgacaatcga ttcatgaatc
    22681 aagaattgcc ttacacgtcc ttgtaataca aaataacaat tcgtaggaac atctccttgt
    22741 ctaaggagca ctgttccttt tttatattcc tctaaatgaa tagattcgag aaaaatccgc
    22801 tgttccactt tagtaaggga tgtatatttc gccatgtact tcaccaatga ttctttcatg
    22861 cttctcccac tgatcacttg aattgatgaa ataattaaat aggaataatc ttatcgcgaa
    22921 ccggctcacg tacctaaacg agcttgttcg cgatttttgt atggccgtaa cgataataat
    22981 acgcaatggt tctccaaatt gaatcgctat aaagtaattg aaggctgatg aatgagaata
    23041 gggataataa gattat
//
