LOCUS       NZ_JAPDMW010000001     20942 bp    DNA     linear   CON 23-JAN-2024
DEFINITION  Paenibacillus alvei strain LF-11/2021
            NODE_1_length_717853_cov_31.503184, whole genome shotgun sequence.
ACCESSION   NZ_JAPDMW010000001
VERSION     NZ_JAPDMW010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus alvei
  ORGANISM  Paenibacillus alvei
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 717853)
  AUTHORS   Fallico,L.
  TITLE     Analysis of the Paenibacillus alvei's inhibition ability against
            multidrug resistant bacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 717853)
  AUTHORS   Fallico,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2022) U.O.C. Microbiologia, Ospedale San Bortolo
            AULSS8 BERICA, Viale F. Rodolfi, 37, Vicenza, Vicenza 36100, Italy
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.14.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 71.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/23/2024 02:12:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,998
            CDSs (total)                      :: 5,902
            Genes (coding)                    :: 5,824
            CDSs (with protein)               :: 5,824
            Genes (RNA)                       :: 96
            rRNAs                             :: 9, 1, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 1, 8 (16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 32 of 78
            Pseudo Genes (incomplete)         :: 65 of 78
            Pseudo Genes (internal stop)      :: 14 of 78
            Pseudo Genes (multiple problems)  :: 27 of 78
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:37:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 180345
            Orig. end                         :: 201287
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAPDMW010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20942
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20942
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20942
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10942](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10942
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            637..1452
                     /gene="spoIIIAF"
                     /locus_tag="OF778_RS00810"
     CDS             637..1452
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAF"
                     /inference="COORDINATES: protein motif:HMM:NF021121.4"
                     /locus_tag="OF778_RS00810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_268623287.1"
                     /transl_table=11
                     /translation="MSWLSQWMKEIIMIILLATFIDLLLPNRSMQRYVKLMLSLIILLT
                     LLSPVLKLFDARLADQLASEWSSTLSSTLTAERNQSTSVNEIRRQGELLAREQEGSALR
                     LAEAEIGSQMKEQLALAFRHSVQNANGTKRNISEEQVQVEQLQVKLTRNAKGEPIIERI
                     ELALSAGQAAVNETDSIDFVKTDGTVEAVKPVHQVQIQSGLIGQEGQETGQSQRSKEIP
                     VAGYTEQLGEEAEQYRSKVTSQAIRSLMTSWIVNAEQIKVEWKRAEPKL"
     gene            1592..2260
                     /gene="spoIIIAG"
                     /locus_tag="OF778_RS00815"
     CDS             1592..2260
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005546704.1"
                     /locus_tag="OF778_RS00815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_021252986.1"
                     /transl_table=11
                     /translation="MLAKWLQQIETWIGKGSNGSKRVRSFRWLLLLGLVGAALILFGSF
                     QPQGSGGGWFGGKGSADKEPPAVGAFDSMETKNSSDKASSNVFESIEQSFEARVKGILE
                     GIVGVGQVDVLVTIDSTEELIVQRNFKDNQQQTEETDSNGGKRHTTQYTRDGQIVTLES
                     SGNQAPIVTKRIKPKVRGVIVVAKGAENATVKKMVVDAVEKGLNVPAYRISVVPRKIAQ
                     "
     gene            2307..3059
                     /locus_tag="OF778_RS00820"
     CDS             2307..3059
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019422922.1"
                     /locus_tag="OF778_RS00820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIIIAH-like family protein"
                     /protein_id="WP_021252985.1"
                     /transl_table=11
                     /translation="MNTKRQTIWLVSMLSLMVVLSAYYLFTEDTTAPAKQTVDNVRSEQ
                     TLKGDATEVGQLPEIKVTEVSTGHGADPSVNGKDAASEAKENSSKSDGTNPSATSTGKD
                     DEAKNAGNETSAAAKEDQEKAMLDKVEAEGVMKRSSIEELQMQRAEKYQQEMEKLMSDL
                     NSTSSEKTAAVHDEMGKLEEHETKLSNLETELQKQYQSAVITQDNDKYQVLVQSNKLEA
                     KDAVEIVDKVMKDLNVTQDKIVVEYVSE"
     gene            3479..3979
                     /gene="accB"
                     /locus_tag="OF778_RS00825"
     CDS             3479..3979
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006676753.1"
                     /locus_tag="OF778_RS00825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="WP_268623567.1"
                     /transl_table=11
                     /translation="MFKIGEIKELIKLLDQTSVQELEIENEGYRLSIRKPGKTEVISVQ
                     PAPAQPTYTPVPTVPAQAAAAVETAPAQPAVDVVADTKEQAGLHKIVSPMVGTFYRASS
                     PDTPPFVNTGDKINEKSVVCILEAMKLMNELLAEVKGEIVEILVENGQLVEFGQPLFLV
                     KLD"
     gene            4028..5371
                     /gene="accC"
                     /locus_tag="OF778_RS00830"
     CDS             4028..5371
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371779.1"
                     /locus_tag="OF778_RS00830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_268623288.1"
                     /sec_met_domain="ATP-grasp (E-value: 5.7e-07, bitscore:
                     24.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 4.9e-09,
                     bitscore: 31.3, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFQKILIANRGEIAVRIIRACRELGIATVAVYSEADRDSLHVRL
                     ADEAYCIGPTSSKDSYLNFTNIMSVATLTECDAVHPGYGFLAENADFADICESCGITFI
                     GPSSNAIERMGDKAVAKQTMKDAGVPVIPGSDGLVENIEEALMIARDIGYPVIIKATAG
                     GGGKGIRIADDEEMLVKQITTAQQEAERAFGNAGVYLEKYLTGMKHVEIQIIADKHGNA
                     AYLGERDCSVQRRRQKLVEEAPCPVLTPDIRMKMGEAAVRAALAVDYSGAGTLEFLFGP
                     DGNFYFMEMNTRIQVEHPVTEMITGIDLIQEMIHVAEGNPLSFRQEDVQLNGWAIECRV
                     NAEDPDRNFMPSAGQIQFYLPPGGAGVRVDSAAYPGCVISPHYDSMIAKLIVWAPTREQ
                     AIERMKRALGEFAIEGIHTTIPFHQRLLRHPKFEQGDFDIKFLEEHEV"
     misc_feature    complement(4031..4045)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.95"
                     /tool="antismash"
     misc_feature    complement(5445..5458)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.49"
                     /tool="antismash"
     misc_feature    complement(5450..5459)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            5478..5888
                     /locus_tag="OF778_RS00835"
     CDS             5478..5888
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019422919.1"
                     /locus_tag="OF778_RS00835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_021252982.1"
                     /transl_table=11
                     /translation="MNQTIIPEFERTDLGNIQIAPDVIAVIAGLATIEVEGVAGMSGGF
                     AGGIAELLGRKNLSKGVKVEVGQREAAVDVNIIVEYGRRIPVIADEIQQNVKRSIEMMT
                     GLHVVEVNVHVHDVHFKSQEKPEETEVSTRVK"
     gene            5956..6495
                     /gene="amaP"
                     /locus_tag="OF778_RS00840"
     CDS             5956..6495
                     /codon_start=1
                     /gene="amaP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019422918.1"
                     /locus_tag="OF778_RS00840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="WP_021252981.1"
                     /transl_table=11
                     /translation="MSRIVDRLLLFVYSLVIGSLSVAAILAALGFIPERLDPTQPLWLQ
                     TTVIAVAAVILLLSIRFVYVSMRRERKSMSSIDQRTDIGDIKISIETIENVALKAASRV
                     RGVKDLKARIRTNESGLDITIRTVVDGETAIPSMTEDVQRQVRDYVQEITGIPVSYVSV
                     YVANIVQTQTFKARVE"
     gene            6511..6741
                     /locus_tag="OF778_RS00845"
     CDS             6511..6741
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019422917.1"
                     /locus_tag="OF778_RS00845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2273 domain-containing protein"
                     /protein_id="WP_021252980.1"
                     /transl_table=11
                     /translation="MWKEIWESHGGRLLGVTAGIFFGILYLIVGFWDMLFFALLVFIGF
                     AIGRQRDLKLGPLFPFQRIGMWMSERWRRLK"
     misc_feature    complement(6816..6829)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.76"
                     /tool="antismash"
     gene            6972..7448
                     /gene="nusB"
                     /locus_tag="OF778_RS00850"
     CDS             6972..7448
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005546713.1"
                     /locus_tag="OF778_RS00850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_021252979.1"
                     /transl_table=11
                     /translation="MKRRIAREMAIQSLYQLEMTEVTPHQAVAMIVQESAQDNEIGVKH
                     EHAEAMHAHVLEWVRATWEHHVEIDELLARYLKGWHVERLSRVDRQILRLATYEMKYRD
                     DVPPKVAINEAINLAKHFGTDESGKFVNGVLGQMMRDMDGASTAEAAKEETTEE"
     gene            7505..8371
                     /gene="folD"
                     /locus_tag="OF778_RS00855"
     CDS             7505..8371
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005546715.1"
                     /locus_tag="OF778_RS00855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_268623568.1"
                     /transl_table=11
                     /translation="MTATLLDGKALSRTIREEITAETAGLKDKGIQPGLAVVLVGEDAA
                     SQVYVNSKHKTCLELGFNSEVHRLPANTSQEELLALVHRLNKEPSIHGILVQLPLPKHI
                     DEKAVIDAIAVEKDVDGFHPVSVGNMVIGDDSLLPCTPAGIMEMLKRNQIDVAGKHAVV
                     IGRSNIVGKPISLLLQRENATVTMCHSRTVNMKEITKQADILVVAIGRANFVDRSYIKP
                     GAVIIDVGMNRLENGKLAGDVDFEDVKEICGPITPVPGGVGPMTITMLMFNTLKAAKRI
                     HHIAHNE"
     gene            8414..9769
                     /gene="xseA"
                     /locus_tag="OF778_RS00860"
     CDS             8414..9769
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005546717.1"
                     /locus_tag="OF778_RS00860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_174808822.1"
                     /transl_table=11
                     /translation="MSDDARILSIKEVNRYIRMKMEGDPRLQDVWLRGEISNFTHHSSG
                     HMYFTLKDSDSRIRTIMFASHNQKLAFRPKEGTKVIARGNITVYERDGQYQFYAMHMQP
                     DGIGSLFMAFEQLKERLNAEGLFGQERKRSIPRYPAAIGVITSPTGAAVRDILITLRRR
                     QPGVAVLLYPVLVQGTQAAGSIAQAIEAMNRSGEVDVLIVGRGGGSLEELWAFNEEVVA
                     RAIAASTIPIISAVGHETDFTISDFVADLRAPTPTAAAELAVANREELRQHLTHVNRRL
                     QSAMNRLLNQNQERLLRAQQSAVFRKPEQLMMKHADKVARLQEQLTYRLQLIQGQSSQR
                     WKELRGRLREQTPVHQVRAARKRLDGNQHQLVQSMAAITKQKRMEAAGMIRQLDALSPL
                     KIMSRGYSLVYDEQEAKLIRSIEEVQLGDVVRVKLSDGQLDCHVWSMKGERE"
     gene            9775..10035
                     /gene="xseB"
                     /locus_tag="OF778_RS00865"
     CDS             9775..10035
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006676761.1"
                     /locus_tag="OF778_RS00865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_021252976.1"
                     /transl_table=11
                     /translation="MENKETIEQLSFEAAMDKLEEIVAKLESGDAPLEQSIELFQEGMM
                     LSKLCSEKLEQVERKIEMVTEQNGEWKRQPYATEETGDSID"
     gene            10001..10942
                     /locus_tag="OF778_RS00870"
     CDS             10001..10942
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005546720.1"
                     /locus_tag="OF778_RS00870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_051249861.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.5e-61, bitscore:
                     201.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQRRRVIRLINYQSAGVFADYVKQQATRIESILPKMLDSKRNTP
                     EPLTQSMHYSLMAGGKRLRPVCVLMACDSLGGNTRAAEPVACAIEMIHTYSLVHDDLPA
                     MDNDDLRRGKPTNHKIYGEAMAILAGDGLLTQAFHCIVQSTRQHGVAAEVSLSIVEELA
                     EYAGMNGMVGGQAADMLGEQGITTLDQLEYIHLHKTSDLIVCSLRAGGRIGGASEQQLQ
                     ALTTYGYKLGLAFQIQDDILDVIGDEAMLGKPKGSDEKSGKVTYPYFIGLEESRQEVER
                     LTEEAKAAIANAGFQKPELLVGMADYLMKRDH"
     misc_feature    11348..11362
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     misc_feature    complement(11519..11531)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.18"
                     /tool="antismash"
     gene            11693..12319
                     /locus_tag="OF778_RS00875"
     CDS             11693..12319
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005546722.1"
                     /locus_tag="OF778_RS00875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_021252974.1"
                     /transl_table=11
                     /translation="MKFSFKHSVRWSVFIFIVTFALAAIFSVVSTSMLEGVGWGIGMVI
                     VLLLVLIGVFFDMMGLSAAAAKETPFHAMASEKVAGAKQAIAIVRNADRFSNFCNDVIG
                     DMTGVISGSATAIVVTNLLYSMDADSAVMKTVTSVVFTGLVSALTVGGKALGKSFAIYY
                     ATPIVLLIGKCFYVLETKFNISFFTVKRSKSKQRKRGKSRAARTD"
     misc_feature    11694..11708
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.25"
                     /tool="antismash"
     gene            12300..14201
                     /gene="dxs"
                     /locus_tag="OF778_RS00880"
     CDS             12300..14201
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005546724.1"
                     /locus_tag="OF778_RS00880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_072727897.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 2.5e-125,
                     bitscore: 412.5, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-07, bitscore:
                     26.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLEQINQPSDLKQLPKEQLEPLAAEIRQFLIEKLAVTGGHLASN
                     LGIVELTLALHYYYDSPKDKMLYDVGHQAYVHKILTGRKDQFDTLRQYKGLCGFVKRAE
                     SEHDVWEAGHSSTSLSAAMGMALSRDLQGQDNRVVAIIGDGALTGGMALEALNHIGHEK
                     RKLMVVLNDNEMSIAPNVGALHNYLCKIRSDRNYKKAKEEVEQLLKKIPAIGGKLAKTA
                     ERVKDGLKYLVVSGMLFEEFGLKYFGPVDGHDIDKLLDIFQQADRIDGPVLVHVVTRKG
                     KGYSPAEADSHKWHGATPYKIESGQPLKSVGTPNYTDIFSDVLIELAEQDERIVAVTPA
                     MPGGSGLLKFEKLYPNRMIDVGIAEQHAATMCAAMAMEGMKPVFAVYSTFLQRAYDQVV
                     HDICRQQANVIFAIDRAGFVGPDGETHQGVYDIPFLRHIPNMVIMMPKDENELRHMMKT
                     AVDYDAGPIAVRYPRNAVVGVPMDTELSPIPIGTWETVRNGDSAAVLAIGPMVQVAEEA
                     AELLRKEGIRIRVINARFVKPLDDEMLHQLGKDRIPVIVLEESSAIGGLGSAVLEWYAN
                     HGVYDMRVKPIGVPDCFVEHGSIKEQRNEVGLTPERVVKEVHSMLFATGGNNRLTRA"
     gene            14247..15074
                     /locus_tag="OF778_RS00885"
     CDS             14247..15074
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005546726.1"
                     /locus_tag="OF778_RS00885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_065293212.1"
                     /transl_table=11
                     /translation="MSIPKERIDVLLVEQGYYTSREKAKAAIMAGLVLANAERIEKAGM
                     KVPRDAAITVKGAVHPYVSRGGLKLEKAIQQFGLNMQDAVMLDIGASTGGFTDCALQNG
                     AQKVYAVDVGYNQLDWSLRNDDRVIVMERTNFRYTEPGDLVGPVPDTASIDVSFISLKL
                     ILPPLARLLAKPGRVVALIKPQFEAGREKVGKSGIVREASTHEQVLREILDFAASIGFQ
                     LEGLTYSPITGGEGNIEFLAYWNVPELTEEEVPHVSRDLIADIVREAHTTFRS"
     gene            15205..15660
                     /locus_tag="OF778_RS00890"
     CDS             15205..15660
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019422908.1"
                     /locus_tag="OF778_RS00890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_021252971.1"
                     /transl_table=11
                     /translation="MGDRWIMGLIGIGLAVWIGYAIRHYMRTPEAMENVCLSERYPQDD
                     EIVALLESAGYEIIGGKYFVPIQIQMNGEELESTKLWIDMVVKRGEQWYIVRIVRERMQ
                     LDWSASAIRRHWGAYFAAYPECDGLLVVDMAERRIRMLHMEFGEAEA"
     misc_feature    15754..15772
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.89"
                     /tool="antismash"
     gene            15781..16230
                     /gene="argR"
                     /locus_tag="OF778_RS00895"
     CDS             15781..16230
                     /codon_start=1
                     /gene="argR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282217.1"
                     /locus_tag="OF778_RS00895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional regulator ArgR"
                     /protein_id="WP_005546729.1"
                     /transl_table=11
                     /translation="MKGQRHIKIREIVMNNDIETQDELVDSLRNAGFHVTQATVSRDMK
                     ELHLIKVPMDNGRYKYSLPIDQRFNPAQKLKRSLLDNFVSVDSAENLVVMKCLPGTANA
                     IAVLMDSIEWPEIMGTVCGDDTILIICRTKELSQSVVDQVMSYIS"
     gene            16255..17979
                     /gene="recN"
                     /locus_tag="OF778_RS00900"
     CDS             16255..17979
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005546731.1"
                     /locus_tag="OF778_RS00900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA repair protein RecN"
                     /protein_id="WP_021252970.1"
                     /transl_table=11
                     /translation="MLVAISIRNLAVIESVQLRFHRGFHVLTGETGAGKSIIIDALGLI
                     GGARGSADFVRYGCERAEVEASFDLAIDHPVWEALSRLGIQGSSEELLIIRRELTAQGK
                     SMCRINGQMVTLTMLREIGELLINIHGQHEHQSLLKVERHLDWLDAYGGEEVAVLKRKY
                     RDDYGCFMALQHELNQLKETSQQAYQMLDLYRFQIEELRNAQLKIGEDESLTEEKRKLA
                     NAEQLMDHVNVSYERLYGQGAMDSVSVAISKLEDVLMYDTVKFQPIIEQMQNAYYQLED
                     AAYQLRDYRENIEFNPERLEQIEDRLDQLTSLKRKYGSTVEEMLEYLAKIEDEADKLEH
                     KDERILKLEAETQERLGKLAKRAQALSDARRELSLELTKRIEAELQHLHMERTRLDVRL
                     DRLQDGQGGHEVDGVSVRFTKNGWDDAEFLISPNPGEPLRPLHKIASGGELSRIMLAMK
                     TIFAEVDRIPVLVFDEVDTGVSGRAAQAIAEKLAEVSRSGQVFAITHLPQVACMADHQY
                     YIEKQVRDERTSTQVHELEDEGRIIELARMLGGVEVTEATMHHAQEMLELAERQKGA"
     gene            18102..19568
                     /gene="spoIVB"
                     /locus_tag="OF778_RS00905"
     CDS             18102..19568
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019422905.1"
                     /locus_tag="OF778_RS00905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIVB peptidase"
                     /protein_id="WP_072727900.1"
                     /transl_table=11
                     /translation="MNPNVKRLLGLMLVILVCLSTTTATFRTYAALPNQLRLFEGQQTK
                     LDLVMPVQASATVDRPDILRVNGENRPTFQLSPNRPISLQSAQSGQAELKLKLFGGIPL
                     KTLKVNVVPNLRVIPGGQTIGVKVKSAGILVVGHHLVKVEGERKVSPGEEAGVRLGDLI
                     TSMNGNRLNDVSKVADIVKQAGENKRPLDLVIRRGDTEVKAQLTPAYDQEDKTWRLGLY
                     IRDSAAGVGTLTFYAPDQGVYGALGHIITDMDTQTPIVVGQGEIVQSHVTSISKSQNGE
                     PGEKRAQFVKESRVLGNIERNTPFGIFGKMVSNPEHSVYKEPIPVAFREEVKVGPAEML
                     TVVNGQQVERYKIEVVHVTKQSAPATKGMVIRITDPRLLQKTGGIVQGMSGSPIIQDGK
                     LIGAVTHVFVNDPSSGYGCFIEWMLQDAGVVLASPQSMNEQGKVHVQRDPSFSFTSRRS
                     HQSSGYVESIRMNTKSVGSLDKSLIIIEKF"
     gene            19696..>20126
                     /locus_tag="OF778_RS00910"
     CDS             19696..>20126
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009591253.1"
                     /locus_tag="OF778_RS00910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator"
                     /protein_id="WP_268623289.1"
                     /transl_table=11
                     /translation="MQKIEILLADDNREFTNLLADFLSEQDDMVVTGVAYNGEEVLQFL
                     EQTRAVPDVLILDIIMPHLDGLGVLERLRNMDLSPQPKIIMLTAFGQESITQRAVQLGA
                     SYYILKPFDMDILANRIRQLAGVASNASVTGGSASNLMTS"
     assembly_gap    20127..20226
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <20227..20524
                     /locus_tag="OF778_RS00915"
     CDS             <20229..20524
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /codon_start=2
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009591253.1"
                     /locus_tag="OF778_RS00915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sporulation initiation factor Spo0A C-terminal
                     domain-containing protein"
                     /protein_id="WP_326848278.1"
                     /transl_table=11
                     /translation="IKGYQYLREAITMVYNNIEILGSITKTLYPAIAEKYKTTPSRVER
                     AIRHAIEVAWTRGNIDSISRLFGYTINISKSKPTNSEFIAMVADKLRIEHKVS"
ORIGIN
        1 atccgctcat catctttatg gttcatttgg tcggaacact gatctatgtc ggtgtatttc
       61 cgcttctatt cttctcagca attctgcata ttgtcagttc catatctgac aaatacaagg
      121 tgactcaact ggcaaacttg atgcggagca tcagtgtggg attgctaggt gttctgttaa
      181 cgatctttct gggcgtgatc tccgtgcaag gagctacgag ctcagtcact gatggggtat
      241 ctattcgaac agccaagtat ataaccggca atttcgttcc tgtaattgga cgcgcattct
      301 cagatgcaac ggataccgtc atttcggcat cgctgctcgt aaaaaatgcg gttgggttgt
      361 caggtgtcat tattttgctg tttttatgtg ccttcccggc aatcaaaata ttgacgcttg
      421 cattaatcta taacgcctcg gcagccatta tgcagccgtt aggagattcc cctgtgcttg
      481 ggtgcctgaa gacgatcggc aagagcatga tctatgtgtt tgcggctcta gctgcggtcg
      541 gtctcatgtt ctttctagca attacgattc tcattacggc aggcaatgtg acggttatga
      601 tgcgctaggc cgcgcggatg aaatggagtg aacgaaatga gctggttaag tcaatggatg
      661 aaagagatca tcatgataat tctactggca acgttcattg atctgcttct gcccaatcgc
      721 tcgatgcagc gatacgtcaa gctaatgctt agcttaatta ttttactaac cttattatca
      781 cctgtcctta agctgttcga tgcaagactg gcagatcaat tagcaagcga atggagctct
      841 acgttgtcat ccacgttaac cgcagagcga aatcagtcaa cgagcgtaaa cgaaatccga
      901 agacaaggag agttgctagc ccgtgagcag gaaggcagtg cgctgcggct tgcagaagcg
      961 gaaattggca gtcagatgaa ggaacagctt gcgcttgcct ttcgtcacag tgttcaaaat
     1021 gccaatggta cgaagaggaa catctcggag gaacaggtac aagtggagca gttgcaagtc
     1081 aagcttaccc gcaatgcgaa gggggaacca atcattgaac ggatagagct tgctctttct
     1141 gccggacagg ctgctgtgaa cgaaaccgat tccatagatt tcgttaaaac tgatggcaca
     1201 gtggaggctg tgaagccggt tcatcaagta cagattcaat caggcttgat tggacaagag
     1261 ggccaggaga cggggcagtc tcagcgatcg aaggaaattc cagtagcagg atacactgaa
     1321 cagctggggg aagaggccga acagtatcgc agcaaggtta cgagtcaagc gatacgctca
     1381 ctgatgacct cttggattgt gaatgcggag caaatcaagg tggagtggaa acgagctgaa
     1441 ccaaagctgt aggacagcca tcctttggtc atgcgttcaa gcaggtgaaa atcatgaaaa
     1501 aacaagcata ttttctatac ggtagcatat aggtgaaata ggacaagtaa gacaagtaag
     1561 acaagtccat tcgataacga aggagtcgat catgttggcg aaatggttgc agcagattga
     1621 aacgtggatc ggaaaaggca gcaacggttc caagcgcgtc cgttcgttcc gctggctgct
     1681 cctgctcggt cttgtcggcg cagcgctcat attgttcggc tcgttccagc ctcagggaag
     1741 cggcggaggg tggttcgggg gcaaaggcag cgcagacaaa gagccgccgg ctgtcggggc
     1801 ctttgactcg atggaaacca agaattcatc tgataaggct tcatcgaatg tattcgagtc
     1861 cattgagcag tcatttgaag cacgcgtcaa aggcattctg gagggaattg tcggcgtcgg
     1921 acaagtcgat gtgcttgtca cgattgactc cacagaggaa ctgattgttc agcgcaactt
     1981 caaggacaat cagcagcaga ccgaagagac agattcgaac ggcggcaagc ggcacactac
     2041 ccaatatacg cgcgatggtc aaatcgtgac gctggaatcc tcgggaaatc aagctccaat
     2101 cgtgacaaag cgcattaagc cgaaggtgcg gggagtcata gtcgttgcga aaggggcaga
     2161 gaatgcgacg gtgaagaaga tggtcgtcga tgctgtcgag aaaggcttga atgtaccggc
     2221 ttatcggata tcggtcgttc cacgcaagat tgctcaatag gtaagcttga acgagaaact
     2281 gaatgaacat taggaggtaa tgaagaatga atacgaaaag acagacgata tggttagtgt
     2341 ctatgctgag cttgatggtc gtattgtccg catattattt gttcacggag gacacaacag
     2401 ctccagcgaa gcaaacggta gacaatgtac gttcagaaca gacgttgaaa ggtgatgcaa
     2461 cagaagttgg gcaattgcca gaaatcaaag tcactgaggt atctacaggg catggtgctg
     2521 atccaagcgt caatggcaaa gacgctgcat ccgaagctaa ggagaacagc agcaagagtg
     2581 acgggaccaa tccttctgcg acaagcactg gcaaggacga tgaagccaag aatgctggaa
     2641 atgagactag cgctgctgcg aaggaagacc aagagaaggc gatgctggac aaagttgaag
     2701 cagaaggtgt tatgaagcgg agctctattg aagaactgca aatgcagcgt gcagagaagt
     2761 atcagcaaga gatggagaaa ctcatgagtg acctgaactc aaccagcagt gagaagactg
     2821 ctgcagtcca tgacgaaatg ggcaagctgg aagagcatga gacgaaatta tcaaacctgg
     2881 aaacggagct gcagaagcag tatcagagtg cagtcatcac acaggataat gataaatatc
     2941 aagtgcttgt gcagagcaat aagcttgaag ccaaagatgc tgttgaaata gtagataaag
     3001 tcatgaagga cttgaatgtg acacaagata agattgttgt agaatatgtc agtgaatagc
     3061 gaatgtactc gaatctagcc cagttgcaaa ctgggctctt tccatttgga acgattatgt
     3121 tataatacta acgtctgtag attgtccttt tttgaaggtt gttcaaaaag acagcttatt
     3181 tttgagaaag caacggaagg tctctcagca tggaatctag cattcaaatc acaaggattg
     3241 tcgcatcgaa tatgtcattt cttctgcggc aacacggcac tctgctatgc atgcagctta
     3301 acagctactt gtgcgcactg ctgaacagat tcggtattat attctgcata gacagcatgc
     3361 gctgagcgtc cttgcggatc tctgttgcgg aataccgctc cctttttgga catgtatttg
     3421 cagtatgaaa ctaccttgct ataagagact tatcaattgt cacgaggagt gaaacatgtt
     3481 gttcaagatt ggcgaaatca aagaactgat caagctgttg gaccaaactt ccgtgcagga
     3541 attggaaatc gagaacgaag gttatcgtct ttccattcgc aagcccggca agactgaagt
     3601 cattagtgtt cagccagcac ctgcacagcc tacatatacc ccggttccaa ctgtacctgc
     3661 acaagcagca gctgcagttg agacagctcc tgcacagcca gcagtagatg ttgttgccga
     3721 cacgaaggag caggcgggat tgcataagat tgtgtctccg atggtaggta cattctatcg
     3781 tgcttcttca ccagacacgc ctccatttgt gaatacggga gataaaatta acgagaaatc
     3841 ggtcgtatgt attttggaag cgatgaagct aatgaatgag ctcttagctg aagtcaaagg
     3901 cgaaattgtt gagattcttg tagaaaatgg ccagttggtt gagttcggcc agcctttatt
     3961 cttggtgaag ctggattagt ggatgctatc atcccgaaca gatgtaaagc caaggaggtt
     4021 taaaacattg aaatttcaga agattctaat tgctaaccgt ggtgaaatcg ctgttcgtat
     4081 cattcgtgct tgccgagaac ttggaattgc aacggttgca gtctactcgg aagccgatcg
     4141 tgattcactt catgtacgtc ttgcagatga agcgtactgt attggcccta catcttccaa
     4201 ggacagttac ttgaacttta cgaatataat gagtgttgct acattgacag aatgtgatgc
     4261 agtacatcct ggctatggtt ttttggcgga gaatgctgac tttgctgata tttgcgagtc
     4321 atgcggcatt acattcattg gtccttcttc caatgcgatt gagcgtatgg gagacaaggc
     4381 tgtagcgaag cagacgatga aggatgcagg agttcctgtc attcctggtt ctgacggtct
     4441 cgttgagaat atcgaagaag ctcttatgat cgcacgcgat atcggttatc ctgtcatcat
     4501 taaggcaact gccggcggcg gtggcaaagg gatccgaatt gcggatgatg aagagatgct
     4561 ggtcaagcaa attacgacag cacaacagga agcagagaga gccttcggta atgccggcgt
     4621 ttatttggag aagtatttga cgggcatgaa gcatgttgaa atccaaatta tcgcagacaa
     4681 gcatggtaat gcagcttatc taggcgaacg tgactgctcc gtgcagcgca gacgtcagaa
     4741 gctggttgag gaagctccat gtccagtgct gacgccagat attcgtatga agatgggcga
     4801 ggcagctgta cgcgcagcac tcgctgttga ctactcgggt gcaggtactt tggagtttct
     4861 gttcggtcca gacggcaatt tctacttcat ggagatgaat actcgtattc aggttgaaca
     4921 tcctgttacc gagatgataa ctggaattga ccttattcaa gagatgatcc atgtagcgga
     4981 aggcaatcca ttatcgttcc gacaagagga tgttcagctt aatggatggg cgattgagtg
     5041 ccgtgttaac gcagaagacc cagatcgcaa ctttatgcct tccgcagggc aaattcaatt
     5101 ctatttgcct ccgggaggag cgggtgtacg tgtggatagc gcagcatatc caggttgtgt
     5161 gatttctccg cactatgatt ccatgattgc gaagctgatc gtgtgggctc ctactcgcga
     5221 acaagcgatt gaacgtatga agcgtgcact cggggagttt gcgatagaag gtattcatac
     5281 aacaattccg ttccatcaac ggttgctgcg gcatccgaag ttcgagcaag gggatttcga
     5341 tattaagttc ctggaagagc atgaagtcta gaacgtcatc atgagtaatt tgtcataaaa
     5401 atagacaaat gctatagtta tgattatgac ggacaagaac tgcctctttt caaaaaataa
     5461 tgaggagtgt gtaacggatg aatcagacga ttattccgga atttgagcgt actgatcttg
     5521 gcaatattca gattgctcct gacgtgattg cagtgatcgc tggtctagct actattgaag
     5581 tagaaggtgt agcgggtatg agcggtggct ttgcaggcgg tattgctgaa ttacttggcc
     5641 gtaagaactt gtccaaaggc gttaaggttg aagttggaca acgtgaagct gcagtagatg
     5701 tgaacatcat cgtagaatat ggtcgtcgca ttcctgtgat tgctgatgag attcagcaga
     5761 acgtaaagcg ctccattgag atgatgacag gtcttcatgt tgttgaagtg aacgtgcatg
     5821 tgcatgacgt gcattttaaa tcgcaagaga aaccggaaga aacggaagta tctacgcgag
     5881 tgaaataatg atggcagtaa accccctcct ggtggcaggg ggtttactgc cattccatga
     5941 ggagggtcgt caagcgtgag cagaattgta gacagactgt tgttgtttgt gtatagtttg
     6001 gtcattggtt cgttatcggt agcagccatt ttagctgcat taggcttcat tcccgaacgg
     6061 cttgatccaa ctcagcctct atggctgcaa acaacagtaa tagcggttgc ggccgttatt
     6121 ttattgctta gcatccgctt cgtttacgtt tcaatgcgtc gtgagcggaa gtcaatgtca
     6181 tcgattgatc aacgcaccga tattggtgat attaagatat cgatagaaac gatcgagaac
     6241 gtggcgttga aggcagcgtc gcgcgtccgt ggtgttaagg acttaaaggc acgaatccgc
     6301 accaatgaat cagggctcga tatcacgatt cgcaccgttg tggacgggga gacggcgata
     6361 ccaagcatga cggaggatgt tcaacgccag gttcgcgatt atgtgcagga aattaccgga
     6421 ataccggttt cttacgtttc ggtatacgtc gcaaatattg tgcagacgca aacctttaaa
     6481 gcgcgcgttg aataggtggt gagctgtccg atgtggaagg aaatatggga gagtcacggc
     6541 ggacgtctac tcggcgtcac ggcgggcatt ttttttggca tcttgtatct aattgttggt
     6601 ttttgggata tgctattttt tgcacttctt gtattcatcg gatttgcaat cggcagacag
     6661 cgggatctga aattaggccc cttgttcccg tttcagcgaa ttggaatgtg gatgtctgaa
     6721 cgttggagaa ggttgaagta gtcctatgga cgctccgaac gactgcttga ccgccggttc
     6781 tggccgacgg aagggaatcg gggagcttca taggattttt ttcacaaata aatcgtaagt
     6841 agatgcatcg aagtgcttaa aatcgtagta acggtggcaa ttgccttgat gaacagtaga
     6901 gtgcatgcgc tagtgaattg aaggaatacg aattcgacat gtcggatgct ttacatgcag
     6961 gaggataaat catgaaaaga cgcatcgcca gagaaatggc tattcaaagt ttgtatcagc
     7021 ttgaaatgac agaggtaacg ccacaccagg ccgttgctat gattgtgcaa gaatctgcac
     7081 aagacaatga aataggtgtt aagcatgagc atgcggaagc catgcatgct catgtattgg
     7141 aatgggtacg agctacatgg gagcatcacg ttgagatcga cgagcttctg gcacgttatt
     7201 tgaaagggtg gcacgttgag cgtttgtcca gagtggatag acagatcctt cgtctggcta
     7261 cgtacgaaat gaaatatcgc gatgatgtcc ctcctaaagt agcgatcaat gaggccatca
     7321 atttggcgaa gcactttggt acggacgagt ccggaaaatt cgtcaatgga gttctagggc
     7381 agatgatgcg tgatatggac ggagcttcta ctgcggaagc tgcaaaggaa gaaacaacag
     7441 aagaatagaa gtaagttcag cttggatgac aatgtcgagt attcggatgg aggcgcagag
     7501 aatgataaca gcaactttat tggatggtaa ggcattatct cgtacaattc gtgaggagat
     7561 tacggcggag accgctgggc tgaaggacaa ggggatacag ccagggctgg ctgtcgttct
     7621 cgttggtgaa gacgctgctt cgcaagtata tgtgaacagc aagcataaga catgcttgga
     7681 gctgggcttc aattcggaag tacatcgtct tccggcaaat acgtctcagg aagagcttct
     7741 ggcccttgtt catcgcttga ataaagaacc ttccattcac ggaattcttg tgcagcttcc
     7801 gctgccgaag catattgatg agaaggctgt catcgatgca attgccgttg agaaggatgt
     7861 ggatggattc catcctgtca gtgtcggtaa tatggtcatc ggggatgact ctttattgcc
     7921 ttgtacgcca gcaggcatta tggaaatgct gaaacgcaac cagattgacg ttgctggcaa
     7981 gcacgctgtt gttattgggc gaagcaacat tgtaggcaaa ccgatatctc tccttcttca
     8041 acgtgagaat gcaacagtta cgatgtgcca ttctcggact gtcaatatga aggagattac
     8101 caaacaggca gacattttgg ttgttgcgat tggtcgcgct aacttcgtgg atcgttctta
     8161 tattaagcca ggtgcagtca ttatcgatgt gggcatgaac cgccttgaga acggtaagct
     8221 ggctggagat gttgactttg aggacgtgaa ggaaatttgc ggcccgatta cacctgtacc
     8281 aggcggtgta ggaccaatga caattacaat gctcatgttc aatacactca aggccgccaa
     8341 acgaatacat cacattgcgc acaacgaata gttgtgcgct gtctgtcatt gggaacgaaa
     8401 gggggcagac aatgtgtccg acgatgcacg aatattatca attaaagaag tgaaccgcta
     8461 catccgcatg aagatggagg gcgatccaag gcttcaggat gtatggcttc gtggagagat
     8521 atcgaacttc acacatcatt caagcgggca tatgtatttc acattgaagg attctgatag
     8581 ccgtatacgt acgattatgt ttgcttcgca caatcaaaag ctggcttttc gtccgaagga
     8641 aggaacgaag gtcattgctc gcggcaatat tacggtgtat gaacgggatg gtcaatacca
     8701 gttctatgcg atgcatatgc agcctgatgg aattggaagt ctgttcatgg ccttcgaaca
     8761 gttgaaggag agattgaacg cggagggatt gttcgggcag gaacgcaagc gaagtatccc
     8821 gcgttatcct gctgcaatcg gcgtcattac ttcgccgaca ggtgctgctg tacgggatat
     8881 cctcattacg ctgcgccgcc gtcagcccgg tgttgcggta ttgctctacc ccgtattagt
     8941 acaaggaaca caagcggcag gatcgattgc tcaggcgatc gaggcgatga accgcagcgg
     9001 cgaggtggac gtgctgattg tgggccgcgg cggaggatcg ctagaagaac tatgggcatt
     9061 caatgaagaa gtggttgcgc gagcaatcgc tgcatcgacg atcccgatca tctcagcggt
     9121 tggacatgag actgacttta cgatttcgga cttcgtagcc gatcttcgag ctcctacacc
     9181 tacggcagcg gccgaattag cggtagcaaa tcgtgaagag ctcaggcagc atcttacaca
     9241 tgtaaatcgc aggctgcaat cggcaatgaa tcgtctcttg aatcagaacc aggaacggtt
     9301 gcttcgggca cagcaatctg ccgtgttccg caagcctgaa cagttgatga tgaagcatgc
     9361 ggataaggtt gcgcgcctgc aggagcagtt aacgtaccgg ttgcagttga tccaaggcca
     9421 atcttcacag cgatggaagg aacttcgtgg tcgattgcgg gaacagacgc cagtacatca
     9481 agtgcgtgct gcacgcaagc ggttggatgg caatcagcat caactcgttc agtcgatggc
     9541 tgctatcacg aagcagaagc ggatggaggc agctgggatg attagacagc tggacgcgct
     9601 tagcccactt aagattatgt caagagggta tagtcttgtg tatgatgagc aggaggcgaa
     9661 gctgatccgc tcgatcgaag aagtgcagct tggagacgta gtgcgggtga aattatcgga
     9721 tggccaattg gattgtcatg tatggtcgat gaaaggagag cgtgaataac tctcatggaa
     9781 aataaagaga ctattgaaca attaagcttc gaggcggcga tggataagtt ggaagagatc
     9841 gttgccaaac tagaaagcgg agacgctcct cttgaacaat caattgagtt gttccaagaa
     9901 ggaatgatgc tctctaagct ttgttcagag aagctggaac aagttgaacg caagatagag
     9961 atggtaaccg agcagaacgg cgaatggaag cgccagccgt atgcaacaga ggagacgggt
    10021 gattcgattg attaattatc aatcggccgg agtatttgcc gattatgtga agcagcaggc
    10081 aactcggatt gaatcgatac tgccgaagat gctggatagc aagcgcaata ctcctgagcc
    10141 gctaacacaa tcgatgcatt attcgttaat ggcaggcggc aagcggctgc ggccagtatg
    10201 tgtgttaatg gcctgtgata gcttaggggg caacacacga gcagcggagc cggttgcatg
    10261 tgccatcgag atgattcata cgtactcatt ggtacatgat gatctgcctg caatggacaa
    10321 tgatgatcta cgccgcggca agccgaccaa tcataaaatc tatggtgagg ccatggcaat
    10381 tctcgctgga gacggtctgt tgacgcaggc tttccactgt attgtgcaga gcacacgcca
    10441 gcatggtgtt gcagctgagg tatccttgtc tattgtagag gaattggcag agtatgcagg
    10501 gatgaacggg atggtcggcg ggcaggctgc tgacatgctc ggtgagcaag ggattacgac
    10561 gttggatcag ctggaataca tccatctgca taagacaagt gatcttattg tatgctccct
    10621 ccgcgcaggc gggcggattg gtggcgcatc ggaacagcag ctgcaagcgc tgacgaccta
    10681 tggttataag cttgggctcg cctttcaaat tcaagatgat atattggatg tcatcggaga
    10741 tgaagccatg ctgggtaagc cgaagggaag cgatgagaag agcgggaagg ttacctatcc
    10801 gtacttcatc ggccttgaag aatcgagaca ggaagtggaa cgcttgactg aggaagcgaa
    10861 ggctgcaatt gcgaatgcag ggttccaaaa acctgagcta ttggttggca tggcagatta
    10921 tttgatgaag cgagaccatt aattggcgag tatttaggca ctatttatga tataataggc
    10981 cttgcgtaga gtggtgcagt attctagtcg gcctaccaac gctgaaggcg ggcctaaaaa
    11041 ttcgctaaag ggcacatcga tgaagttcct ggtgttggct ttcgacgccc agtcgggggc
    11101 tgatgctggg agttaaggtt gtggggcgat ccacaatggc atgtgggcgt tgaccccgct
    11161 tccgcggagg cccaagtgcg tggtatgacg ccctcgagcg tcgcattacg gcttggggta
    11221 tgaacctaca ttacgagtcg cacattgcaa ttcttcattc tattatgaag cgtgatgtac
    11281 gtacccggct tgtttgtagc gtagcctgcc ttgagtgagc ctgcggggat tgcggatgtg
    11341 tagattcggt ggacttcggc caaagtacgc atgaatcgta tgccgtatga aatctagctt
    11401 gcaaaagagg ctatgggttg gttcagggct gcccgaggaa aactcctaga ctgttcactg
    11461 gcgtgaagct tcttaaggat tatagtgtgg actaagtggt aattcagtct ggcgattggt
    11521 gacaacgtca aggcgctctt aattggaaac ggcctgctcg gcgacgagga ggcgagcatc
    11581 tgggaaaacc tactggacct aagccacagc gtttacttga gaagttgcca ctcttaactt
    11641 tacgtaactg atttgacagt tctaacacat aaaggatgga acatcacata caatgaaatt
    11701 ctctttcaaa cattccgttc ggtggagcgt atttattttc atcgtcacat ttgctctagc
    11761 agctattttt tccgtcgtat cgacttcgat gctggaggga gtaggctggg gcatcgggat
    11821 ggtgatcgtg ctcctactcg tgctcatcgg agtgtttttt gatatgatgg ggttatctgc
    11881 agcggcagcg aaggagacac cttttcacgc catggcttct gagaaggttg ctggcgcgaa
    11941 gcaggcgatc gcaatcgttc gtaacgcaga ccgattctcc aacttctgta atgacgtgat
    12001 cggcgatatg actggagtaa tcagtgggtc ggctacagca attgtcgtta cgaacttgtt
    12061 atattcgatg gatgctgact ccgcagtaat gaagacggta acgagcgttg tcttcacagg
    12121 actcgtatca gcattgacgg ttggcgggaa ggcactcgga aaatcctttg ctatttatta
    12181 cgccactccg atcgtcctgc taattgggaa gtgtttctac gtgttggaga cgaagttcaa
    12241 tatttcattc ttcaccgtga aacgcagcaa atcgaaacaa cgaaagcgag ggaaatcccg
    12301 tgctgctcga acagattaat caacctagcg acttgaagca gttgcctaag gagcaactgg
    12361 agccgctagc ggccgaaatt cgtcaattct taattgaaaa gctggcagtg accggaggtc
    12421 atctagcatc taacttgggg attgttgagc taacgcttgc cctgcattat tactatgaca
    12481 gcccgaagga caaaatgtta tacgacgttg gccatcaagc ctacgttcac aaaatattaa
    12541 caggacgcaa ggatcagttc gatacattgc gccaatataa aggtttatgc ggctttgtga
    12601 agcgtgcaga gagcgaacac gatgtatggg aagccggaca cagcagtacg tctttgtccg
    12661 ccgcaatggg gatggcattg tcccgtgacc tgcaaggtca ggataatcgg gtagtcgcaa
    12721 tcattggaga cggtgcgctc acaggcggta tggcgctgga agcattgaac catatcgggc
    12781 atgaaaagcg caagttgatg gttgtgctga atgacaacga aatgtccatt gcgccaaatg
    12841 taggagcatt acataattat ttgtgtaaaa ttcgctctga ccgcaactat aaaaaagcca
    12901 aagaagaagt tgaacagttg ctcaaaaaaa ttccggctat tggcggtaag ctggctaaaa
    12961 cggcagaacg cgtgaaggac ggactgaaat acctagtcgt ctccggcatg ctgttcgaag
    13021 aattcggctt gaaatatttt ggccctgtag atggtcatga tattgataag cttctggaca
    13081 ttttccagca ggcagaccgt atcgatggac cggttctcgt ccatgttgta acccgcaaag
    13141 ggaaaggata ttcaccagct gaagccgatt cccataaatg gcatggggca acaccttata
    13201 agattgaatc cggccagccc cttaaatcag tgggcacgcc gaattacacc gatattttca
    13261 gtgatgtgct cattgagctt gctgagcaag acgagcgaat cgtggcagta acacctgcaa
    13321 tgccaggcgg atcaggactc ttgaagttcg agaagctgta tccgaaccgg atgattgatg
    13381 taggtatcgc agagcagcat gcagcaacga tgtgcgctgc tatggctatg gaaggaatga
    13441 agcctgtatt tgcggtatat tcaactttcc tgcagcgagc gtacgatcag gttgtacatg
    13501 atatttgccg tcaacaagct aatgtcatct ttgcaattga tcgagcgggc ttcgtaggcc
    13561 cagatggaga gacgcatcaa ggggtatatg atataccatt cttgcgtcat atcccgaata
    13621 tggtcattat gatgccgaag gacgagaatg agcttcgtca tatgatgaag acggctgttg
    13681 attatgacgc aggcccgatt gccgttcgct atccgcgtaa tgcggttgta ggggtgccaa
    13741 tggacaccga attgagcccg attccaatag gaacgtggga aaccgttcgg aatggagatt
    13801 cagcggctgt tctggctatc ggtccgatgg tgcaggttgc agaggaagca gcagagttgt
    13861 tgcgcaaaga aggcattcgt attcgagtga ttaatgcgag atttgttaag ccgcttgatg
    13921 acgagatgct gcatcagcta gggaaggatc gcattccggt aatcgtgttg gaagaaagct
    13981 cggcaatcgg aggtttaggt agtgctgtac tggaatggta tgctaaccat ggcgtttacg
    14041 atatgagagt gaagccaatt ggggttcctg attgcttcgt cgaacatggt agcattaagg
    14101 aacagcggaa tgaagttggc ttaacacctg aacgggttgt gaaagaggtt cattcgatgt
    14161 tattcgcaac aggcggcaat aatcggttga ctcgggctta attatgttcg cattgatgaa
    14221 tgaatggaat gagacgggag tacagaatgt ctataccgaa ggaacgaatt gatgtcctgc
    14281 tcgtcgagca ggggtattat acgagtagag agaaggccaa ggctgccatt atggcaggcc
    14341 ttgtgcttgc aaatgcggaa cgaattgaaa aggctggcat gaaagtaccg cgtgatgctg
    14401 caattaccgt gaagggagcg gttcatcctt atgtgagccg cggcggactt aagctggaga
    14461 aggcgattca gcaattcgga ttgaacatgc aggacgctgt aatgcttgat attggagcat
    14521 ctactggggg atttaccgat tgcgcattgc aaaatggtgc acagaaggtg tatgcggtag
    14581 atgtcggcta caaccagctt gattggtctt tgcgcaatga tgatcgggta atcgtcatgg
    14641 agagaacgaa tttccgatat acggaaccag gggatttagt aggaccggta ccggatacag
    14701 cttctattga tgtttctttt atttccttga aactgatcct accaccactt gcgcgattgc
    14761 tggctaagcc tggacgggta gttgcactga ttaagcctca attcgaagca gggcgtgaga
    14821 aggttggcaa atcgggaatt gttcgtgaag caagcacaca tgagcaggtg ttgagagaga
    14881 ttcttgattt tgctgcctcg atcggtttcc aattggaagg gttaacgtac tctccaataa
    14941 cgggcggaga gggcaatatt gaatttctag cgtactggaa tgtgcctgaa cttacggaag
    15001 aagaagtgcc gcatgtatca cgcgatctga tcgctgacat cgtgagggag gcacatacta
    15061 cgttccgatc ctagctggca atggaacatg ctgtagaaga aactcatccg ggacaagcat
    15121 ccgtcggatg agtttctttt gcaccatagc acgtatctaa tcaaatctat atgcgcatag
    15181 gctgcgaacc aggggtgaat ttcgatgggt gatcgttgga tcatgggatt gatcggaatt
    15241 ggtttggctg tatggattgg atatgcaata cgacattata tgcgaacacc tgaagcgatg
    15301 gagaatgtgt gcttatccga gagatatccg caggatgatg aaattgtcgc attgcttgag
    15361 tcagcgggtt acgagatcat tggcggcaag tattttgtgc caattcagat tcagatgaac
    15421 ggagaagagc tagagtccac gaaattgtgg attgatatgg tcgtcaaacg gggcgaacaa
    15481 tggtatattg ttcgtatcgt acgcgaacgg atgcagctcg attggagcgc tagtgcgatt
    15541 cgcagacatt ggggagctta cttcgcggca tatcctgaat gtgatgggct gcttgtcgtt
    15601 gatatggcag agcggcgaat tcgcatgctt catatggagt ttggggaagc agaagcttga
    15661 cccttgcaag attaggcgta ggtatgaaag aatggcaagc gaacaatgca atatgaaagt
    15721 tatcgcaata agcaaataat aagtcatgga attatggtgt agacagtatg gagggcatgc
    15781 atgaaaggac aacgacatat taaaatccga gaaatcgtaa tgaataacga tattgagacg
    15841 caagacgagc tggtggattc attgcgcaat gcagggttcc atgttactca agcaactgta
    15901 tctcgggata tgaaagaatt gcatctcatt aaggtgccaa tggacaatgg ccgatataaa
    15961 tattcactcc caatcgatca gcgcttcaat cctgcacaga agttaaagcg gtcacttctt
    16021 gataacttcg tcagtgtaga cagcgctgag aacttagtag tcatgaagtg tctaccaggt
    16081 acagcaaatg cgatcgctgt attgatggac tcgattgaat ggcctgaaat tatgggcacg
    16141 gtatgcggtg atgatacaat cttgatcatt tgccgtacca aagaattgag tcagagtgtt
    16201 gttgatcaag tgatgagtta catttcataa gtgttcttcc gggaggggtt cttcttgcta
    16261 gtagctatat ctatccgcaa tttggcggtt attgaatcgg tacagctgcg gtttcaccgt
    16321 ggatttcatg tcttaacggg ggaaacgggc gcgggcaagt cgatcattat tgatgcgtta
    16381 ggtcttatcg gaggagcaag gggatcagca gattttgttc gatatgggtg tgaacgcgcg
    16441 gaagtcgagg cttcgttcga tcttgccatt gatcatccgg tatgggaggc gctttcccgc
    16501 ttagggattc agggaagcag tgaagagctc ctcattattc gcagggaatt gaccgcgcag
    16561 ggcaagagca tgtgccggat caatggtcaa atggttacgt tgacgatgct gcgcgaaatc
    16621 ggtgagctgc tcataaatat tcatgggcag catgagcacc aatccctgct caaggttgag
    16681 cgtcacttgg actggctcga tgcttatggc ggggaagagg ttgctgtact taagcggaaa
    16741 tatcgtgatg attacggatg cttcatggcg ctgcagcatg aattgaatca attgaaggaa
    16801 acgagtcagc aagcctacca gatgcttgat ctgtaccggt tccagattga ggagctgcgc
    16861 aatgcacagt taaaaattgg cgaggatgaa tcattaacgg aagaaaagcg caaactagcc
    16921 aatgcggagc agcttatgga tcatgtaaat gtatcttatg aacgcttgta tggccaaggt
    16981 gcaatggatt ccgttagtgt cgcaatttcc aaacttgaag atgtgctcat gtacgacaca
    17041 gttaagtttc agcctataat tgagcaaatg caaaatgcgt attatcaact ggaagatgcg
    17101 gcttaccagc tccgcgatta ccgtgagaat atcgagttca atccggaacg ccttgaacaa
    17161 attgaggatc gactggatca gctgacttca ttgaagcgca agtatggctc aactgttgaa
    17221 gagatgcttg aatatttagc caagattgaa gatgaagctg acaagctgga acataaggat
    17281 gaacgcatat tgaagctcga agcagagaca caagaacgtc tgggtaagct cgctaagcga
    17341 gcgcaagccc tgagtgatgc tcgccgagag ttatcactgg aattgacgaa gcgaattgaa
    17401 gcggaactgc agcatcttca tatggaacgt actcggctcg atgtccgttt ggatcgattg
    17461 caggatggac aaggcgggca tgaggtcgac ggtgtatctg ttcgcttcac gaagaatgga
    17521 tgggatgatg cagagttcct tatttcaccg aaccctggag aaccattgcg tccgctccat
    17581 aagatcgcat ctggcggtga actgtcacgt atcatgcttg ccatgaagac aatctttgcc
    17641 gaagttgatc gaatcccagt gctcgtattt gacgaagtgg atactggcgt aagtggccgg
    17701 gccgctcaag ccattgctga gaagcttgct gaagtgtctc ggagtggaca agtattcgct
    17761 attactcatc ttccacaagt tgcttgcatg gctgaccacc aatactacat cgagaagcag
    17821 gttcgagatg aacggacttc tactcaggta catgaattgg aggatgaagg tcgtattatc
    17881 gagcttgctc gcatgctagg cggtgtggaa gtaacggaag cgactatgca tcatgcacaa
    17941 gaaatgcttg aattggctga acgtcaaaaa ggtgcgtaat tctaagggat ttaggaatca
    18001 ttttcactta taaaacgtag gggccgggga taccttaaag ttacgaaatg ggcacgtctc
    18061 ttttcgtcaa gcttccgtct aacaaaggag tgtgaccacc tttgaacccc aacgtcaaac
    18121 gactgcttgg cctaatgctc gtcattcttg tatgcttaag cactacaaca gcaacctttc
    18181 gcacgtatgc ggcgctgccg aatcaactga ggttatttga aggacagcaa acgaagcttg
    18241 atctcgtgat gcctgttcag gcttcagcga cggtagatcg accggatatt ttgcgtgtga
    18301 acggcgagaa tcgacctaca ttccaattat caccgaatcg tccaatttca ttacagtcag
    18361 cccaatctgg tcaagcagag ctgaaattga agctgttcgg aggcattcca ctcaagacat
    18421 tgaaagtgaa tgtagttccg aatttgcgtg tcattcccgg aggccaaacg attggcgtca
    18481 aagtcaaatc agcaggcatc cttgttgtcg gccatcatct tgtgaaggtt gagggagaac
    18541 gcaaagtatc tccaggtgaa gaagcaggtg ttcgccttgg tgatctcatt acgagtatga
    18601 acggaaatcg attgaatgat gtaagcaagg ttgcggatat cgtgaagcag gctggcgaga
    18661 acaaacgtcc acttgatctt gtaattcggc gcggcgatac tgaagtgaaa gctcagttga
    18721 cccccgcgta cgatcaggag gacaaaacgt ggcggctagg cttgtacatc cgagattcag
    18781 cagccggagt aggaactttg acgttctatg ctccagacca aggagtgtat ggggcgcttg
    18841 gacatatcat tacggatatg gacacgcaga ctccgatcgt ggtggggcaa ggtgaaattg
    18901 tccagtccca tgtaacttcc atttcgaaaa gtcaaaatgg agaaccaggt gaaaaacgtg
    18961 ctcaatttgt gaaggaaagc cgtgttttag gcaatatcga acgcaatacg ccatttggca
    19021 tttttggtaa gatggtatcg aatccagaac atagtgtata taaagaaccg attcctgttg
    19081 cattccgcga agaggttaag gtgggacctg ccgaaatgct gaccgtggtg aatggtcaac
    19141 aagtggaacg atacaagatt gaagtcgtcc atgttacgaa gcaatcagca cctgcaacca
    19201 aagggatggt tatccgcata acagatccgc ggctgctgca aaaaaccgga ggcattgtgc
    19261 aagggatgag cggcagtccg attattcaag atggcaaatt gattggtgca gttacgcatg
    19321 tgttcgtcaa tgatccaagc tcaggctatg gatgctttat cgaatggatg ctgcaggatg
    19381 ctggtgttgt cctggcttca cctcagtcaa tgaatgaaca agggaaggtt cacgttcaac
    19441 gtgatccttc tttttctttt acgtcacgac gatcgcatca atcttcagga tatgtcgaat
    19501 cgatacgaat gaatacgaaa tctgttggat cgttggacaa atcattaatt ataatagaaa
    19561 aattttaaaa aataaagaaa aaaagttttc gacagaagga atttcatctt tgatgtcgaa
    19621 taacatgatc tggaagcgat aaacaccaaa ccggttacta tcgtgtgcga aactttgaca
    19681 agggaggatc ccaagttgca aaagatcgaa atattgttag cggacgacaa cagagaattt
    19741 acaaatttgt tggctgattt cttatccgaa caagacgaca tggtcgttac tggtgttgcc
    19801 tataatggcg aagaggtgct ccaattcctt gagcagacga gagcggtgcc tgacgtgctc
    19861 attctcgata ttattatgcc tcatttggat ggtttgggtg tacttgagcg cttgcgcaat
    19921 atggacttgt ccccgcaacc gaagatcatt atgctcacag ccttcggcca agagagcatt
    19981 acgcaacgtg ctgttcaact tggcgcatcc tattacatat tgaagccttt cgatatggac
    20041 attttggcga atcgtattag acagctggca ggtgttgcat ccaatgcttc ggtaactgga
    20101 ggatctgcta gtaacttaat gacatcnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20221 nnnnnntatt aagggatacc agtacttgcg cgaagcaatc acgatggtgt acaacaatat
    20281 cgaaattttg ggctccatca cgaaaacgct gtatccagcg atcgcggaga agtacaaaac
    20341 gacaccaagc cgcgttgagc gggcgatccg ccatgcgatc gaagtagcat ggacgcgtgg
    20401 caacatcgac agcatcagcc gtctatttgg ctacacaatc aacatcagta agtcgaagcc
    20461 tacgaacagc gaatttatcg ctatggtcgc tgacaagctg agaattgagc ataaggtgtc
    20521 gtaaatgtct taacggcgtg gcttttcggg atctttttat tgtgtacttg aatagagagc
    20581 atggggttga taaattggcg ggtgtgaaaa aaggtcatat ccgtcaatac atctcctatg
    20641 ttcaagaaag aggtaagtac acagtactaa ctcgactgcg ctgctttcaa aatcgtcctt
    20701 ttaatggctc gtcttctttt tctgagagtg gtttcgtcaa ttcctatccg attagccata
    20761 tgacgattga taatctcgta atgtcctgaa tcattattcg actaatcctc gtgattatct
    20821 tcgatagtta gtgggaaatt tccgtccgcc aacgctcaga tccgtcagca gctcccgttc
    20881 atgtacacgc gcaacctttc gttagcttga gcggttatga gcgaccacaa catccgcatg
    20941 tt
//
