LOCUS       NZ_CP086140            21053 bp    DNA     circular CON 20-JAN-2024
DEFINITION  Clostridium estertheticum strain CF016 chromosome, complete genome.
ACCESSION   NZ_CP086140
VERSION     NZ_CP086140.1
KEYWORDS    RefSeq.
SOURCE      Clostridium estertheticum
  ORGANISM  Clostridium estertheticum
            Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
            Clostridium.
REFERENCE   1  (bases 1 to 5053333)
  AUTHORS   Wambui,J., Stevens,M.J.A. and Stephan,R.
  TITLE     Clostridia strains as spoilage organisms
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5053333)
  AUTHORS   Wambui,J., Stephan,R. and Stevens,M.J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-OCT-2021) Institute for Food Safety and Hygiene,
            University of Zurich, Winterthurerstrasse 272, Zurich, Zurich 8057,
            Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: OCT-2021
            Assembly Method                   :: unicycler v. 1
            Assembly Name                     :: CF016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150x
            Sequencing Technology             :: Nanopore/Illumina miniseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/20/2024 05:10:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,249
            CDSs (total)                      :: 5,114
            Genes (coding)                    :: 5,019
            CDSs (with protein)               :: 5,019
            Genes (RNA)                       :: 135
            rRNAs                             :: 15, 14, 13 (5S, 16S, 23S)
            complete rRNAs                    :: 15, 14, 13 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 22 of 95
            Pseudo Genes (incomplete)         :: 78 of 95
            Pseudo Genes (internal stop)      :: 14 of 95
            Pseudo Genes (multiple problems)  :: 16 of 95
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:27:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4024989
            Orig. end                         :: 4046042
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP086140.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="darobactin"
                     /product="triceptide"
                     /region_number="8"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     darobactin_precursor) or darobactin_rSAM)"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     triceptide_precursor) or triceptide_rSAM)"
                     /tool="antismash"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and darobactin_precursor) or darobactin_rSAM)"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /kind="chemical_hybrid"
                     /product="darobactin"
                     /product="triceptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11053](-)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and darobactin_precursor) or darobactin_rSAM)"
                     /neighbourhood="10000"
                     /product="darobactin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11053)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and darobactin_precursor) or darobactin_rSAM)"
                     /neighbourhood="10000"
                     /product="darobactin"
                     /protocluster_number="1"
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11053](-)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(10001..11053)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="2"
     gene            complement(597..1265)
                     /locus_tag="LL065_RS18995"
                     /old_locus_tag="LL065_18965"
     CDS             complement(597..1265)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015613560.1"
                     /locus_tag="LL065_RS18995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_18965"
                     /product="ABC transporter permease"
                     /protein_id="WP_226135805.1"
                     /transl_table=11
                     /translation="MIVIKYLFENYEDMLTLLLQHVHLVVISVAISLFIAIALGSLLLH
                     SRWASMIVLSLFGVLYSIPSLAMFAFLIPVLGLGEKTAVIVLIIYNQYILVRNILMAFQ
                     SIDTSIIEAARGMGFNSRQLFIDIQLPLAGPIIIGGTRIAIVSTIGIATIASVINAGGL
                     GVILFDGLRMNYIIKILWGTIMAAGLALIANQILFFIEKIADRKAKGEYNCKDKKEVLN
                     "
     gene            complement(1252..2250)
                     /locus_tag="LL065_RS19000"
                     /old_locus_tag="LL065_18970"
     CDS             complement(1252..2250)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015613559.1"
                     /locus_tag="LL065_RS19000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_18970"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_226135807.1"
                     /transl_table=11
                     /translation="MTTAIEFIKVSKKFNNSKEYSVSEVSLSIEKGSFITVLGTSGSGK
                     TTLMKMINGLYEATSGEILFFGENIKNLNVEKHRRKIGYVIQQIGLFPHMTVEQNIATV
                     PKMLHWDNNKITERVEYLLKLVGLSTDEFKKRYPRQLSGGQQQRVGLARAMAADPDIML
                     MDEPFGAIDAITRQNLQDELISIQKKLNKTIVFVTHDVNEAFKLGDKVIVMDKGKIQQF
                     DSPYNILFKPANDFVARLVSSEDALQKLKYLKAELAMIPLELPVNHEGVRVGKEESLYD
                     VLTAFLNNNVKTVIVEDDKHRVIGKINWSQLNIEGVRERQDIYEKPGDDCD"
     gene            complement(2343..3269)
                     /locus_tag="LL065_RS19005"
                     /old_locus_tag="LL065_18975"
     CDS             complement(2343..3269)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015613558.1"
                     /locus_tag="LL065_RS19005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_18975"
                     /product="glycine betaine ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_226135809.1"
                     /transl_table=11
                     /translation="MNKIFFALPLLAIVLTAGIFAGCSKSTGSNPNTANGSVSKPTIKV
                     GSKNFTESLVLGELYADALEHAGYKVDRKLNLGDAVVHTSLVNGDIDLYPEYTGTGLLS
                     ILKEAPMYDSKAVYDEVSAKYKDKFKLIWLAPSAANDSQGLVISKKASDQYNVHTISDL
                     QKNASQIRFASQGEFDKRSDGLQALIKAYGPFNFKDEKLYDNGLKYDVLKNDKADLAVA
                     YTTEGQLSDSQFVVLEDDKHVWPPYNVAPVVRQDILVKNSDIKDILNKVTAKLDNKTLI
                     KLNAEVDIDKKEYKTVAKEFYNQEFGK"
     gene            complement(3297..3935)
                     /locus_tag="LL065_RS19010"
                     /old_locus_tag="LL065_18980"
     CDS             complement(3297..3935)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015613557.1"
                     /locus_tag="LL065_RS19010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_18980"
                     /product="ABC transporter permease"
                     /protein_id="WP_226135811.1"
                     /transl_table=11
                     /translation="MLNEIVKFLLSNIKQYYTAVLIHISISITAVLISIAIAVPLGILC
                     SKSSKVLYPVMNFFNFLRVVPSLAILVLAIPILGTGFTPALVALIILAVPPILINTYLG
                     FKNINPSIIESAEGMGMGYRELLFKVQLPLAMPLIITGVRTSSVEVISSATLAAYIGAG
                     GLGDFIFTGLSMNDYAMLLTGGISVAILSVIAEIILFFLQQGITRYQRN"
     gene            complement(4176..4634)
                     /locus_tag="LL065_RS19015"
                     /old_locus_tag="LL065_18985"
     CDS             complement(4176..4634)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024865.4"
                     /locus_tag="LL065_RS19015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_18985"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_226135813.1"
                     /transl_table=11
                     /translation="MVDKKFYEARYTPEQQKLAEEIIGMEKVALDKFFKGDMSGYLDLW
                     SKDNFTYFDAGTEERSDTYEEVAHFLKTVVEGNMHADSYDFHAPRVQFGEDIAILTFQL
                     HADTSMIEMHYNVIEIFQKDASGWHVIHSTWALITPFSPNVKKPKVVI"
     gene            complement(4923..5390)
                     /locus_tag="LL065_RS19020"
                     /old_locus_tag="LL065_18990"
     CDS             complement(4923..5390)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005924656.1"
                     /locus_tag="LL065_RS19020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_18990"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_226135815.1"
                     /transl_table=11
                     /translation="MEVIICKAELQDLDTLMEWRMEVLREVFSVPKDMQMSELTEANHN
                     YYKEMLLNEGHLSCFAWKKDEIIGCGGMCVYKEMPSPDNPTGKCAYLMNIYTRPQFRNS
                     GVGEKVVHWLVEQAKQKGITKIYLETSDSGRRLYEKAGFTDMYGYMKLDKF"
     gene            complement(5390..5668)
                     /locus_tag="LL065_RS19025"
                     /old_locus_tag="LL065_18995"
     CDS             complement(5390..5668)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LL065_RS19025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LL065_18995"
                     /product="hypothetical protein"
                     /protein_id="WP_226135817.1"
                     /transl_table=11
                     /translation="MLDERRAITRRELDRMTKAKPYIDEQNLSYIVAYVVANGTRSFVS
                     KIRKSMEKHPHAYMVPKFFIQIANMPLTPNGKVDSGALPVVLKAGDL"
     misc_feature    complement(5813..5830)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.18"
                     /tool="antismash"
     gene            5880..6326
                     /locus_tag="LL065_RS19030"
                     /old_locus_tag="LL065_19000"
     CDS             5880..6326
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017885.4"
                     /locus_tag="LL065_RS19030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_19000"
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="WP_226135819.1"
                     /transl_table=11
                     /translation="MGTDDSCCKGFFITHKRIRHITINSDLPKMMQRIVLAHEIGHAVL
                     HAKSGALAKFQDMLVLDAGDTTENEANPFASKLLLRDKDVMEALNSDCYFNQVAASLYV
                     PAEMLDFKFRVMKRKGFALNAPYIAQGNFLKDFEKTIQYCPNDI"
     gene            complement(6409..6978)
                     /locus_tag="LL065_RS19035"
                     /old_locus_tag="LL065_19005"
     CDS             complement(6409..6978)
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013756.4"
                     /locus_tag="LL065_RS19035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_19005"
                     /product="flavin reductase"
                     /protein_id="WP_226135821.1"
                     /transl_table=11
                     /translation="MKKKFGAKIGLVPYASVVIGTYDENGNPDAMNVGWAMQVGSKEVA
                     INILKHKTLDNLKESKAFTMAFVTKDTMVASDYVGLVSAAKTPNKIEKSGLTCRQSDYV
                     NAPEFEEYPMTFHCDVISITEEFGNTRIVGEIKETTIDDRYLGNDNLPDFRKMGIVWFE
                     DTHKDYVLMGDVAGKAFSVGKKLKEE"
     gene            complement(7051..8037)
                     /locus_tag="LL065_RS19040"
                     /old_locus_tag="LL065_19010"
     CDS             complement(7051..8037)
                     /NRPS_PKS="Domain: PKS_ER (16-326). E-value: 1.2e-35.
                     Score: 115.0. Matches aSDomain:
                     nrpspksdomains_LL065_RS19040_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024989.4"
                     /locus_tag="LL065_RS19040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_19010"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_226135823.1"
                     /sec_met_domain="ADH_N (E-value: 1.4e-08, bitscore: 32.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.6e-14, bitscore:
                     50.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQEMQAIRLTQACSIEELKPTAVNRPEVKPGHALVKVKAFGVNE
                     SEVTSRKGLSSADFSYPRILGIEGVGVIEEVAEDSQLKVGQQVATMMSGLGRAIDGSYA
                     EYMLIAESNLIAFESKLPWEILGAVPEMVQTAYGSLTTGLNLKKGDTLLIHGGTSTVGI
                     TAAVLAKSMGATVLSTSRKLDKFDALKSFGVDFPILDDKDFADKVREIAPRGVDKILEL
                     VGTNVVPQDMALLKAAGKLCFTGALNNTWTFDNFSPYQIPFGKYFTSYAGGVSDLPSPI
                     LNDILRKIEEGESKLPIAKVYQGLEEVGEAQANLESGQFIGKHVVVL"
     aSDomain        complement(7060..7989)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LL065_RS19040_PKS_ER.1"
                     /evalue="1.20E-35"
                     /label="LL065_RS19040_PKS_ER.1"
                     /locus_tag="LL065_RS19040"
                     /protein_end="326"
                     /protein_start="16"
                     /score="115.0"
                     /tool="antismash"
                     /translation="EELKPTAVNRPEVKPGHALVKVKAFGVNESEVTSRKGLSSADFSY
                     PRILGIEGVGVIEEVAEDSQLKVGQQVATMMSGLGRAIDGSYAEYMLIAESNLIAFESK
                     LPWEILGAVPEMVQTAYGSLTTGLNLKKGDTLLIHGGTSTVGITAAVLAKSMGATVLST
                     SRKLDKFDALKSFGVDFPILDDKDFADKVREIAPRGVDKILELVGTNVVPQDMALLKAA
                     GKLCFTGALNNTWTFDNFSPYQIPFGKYFTSYAGGVSDLPSPILNDILRKIEEGESKLP
                     IAKVYQGLEEVGEAQANLESGQFIGKHVV"
     CDS_motif       complement(7543..7593)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LL065_RS19040_0001"
                     /evalue="2.20E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="LL065_RS19040"
                     /protein_end="165"
                     /protein_start="148"
                     /score="13.9"
                     /tool="antismash"
                     /translation="GDTLLIHGGTSTVGITA"
     misc_feature    8295..8311
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: medium, score: 26.46"
                     /tool="antismash"
     gene            complement(9321..9779)
                     /locus_tag="LL065_RS19045"
                     /old_locus_tag="LL065_19020"
     CDS             complement(9321..9779)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024865.4"
                     /locus_tag="LL065_RS19045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_19020"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_226135826.1"
                     /transl_table=11
                     /translation="MVDKKFYEARYTPEQQKLAEEIIGMEKVALDKFFKGDMSGYLDLW
                     SKDNFTYFDAGTEERSDTYEEVAHFLKTVVEGNMHADSYDFHAPRVQFGEDIAILTFQL
                     HADTSMIEMHYNVIEIFQKDASGWHVIHSTWALITPFSPNVKKPKVVV"
     gene            complement(10001..11053)
                     /gene="acgM"
                     /locus_tag="LL065_RS19050"
                     /old_locus_tag="LL065_19025"
     CDS             complement(10001..11053)
                     /codon_start=1
                     /gene="acgM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: darobactin_rSAM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_rSAM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009533157.1"
                     /locus_tag="LL065_RS19050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_19025"
                     /product="radical SAM/SPASM domain protein, ACGX system"
                     /protein_id="WP_226135828.1"
                     /sec_met_domain="PTHR43273 (E-value: 1.7e-39, bitscore:
                     133.9, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 8.4e-16, bitscore: 56.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.7e-06, bitscore: 25.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.7e-10, bitscore:
                     38.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.1e-08, bitscore: 32.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="darobactin_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /sec_met_domain="triceptide_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYFAFQWHITEDCDQRCKHCYIFAENTKKNIISMEWKDMKKTI
                     VNIEDFCKTYGRLPYLYITGGDPILHPDFWKLMDLVKEKQIPFTILGNPFHLTEAVCQR
                     LHDCGCEKYQLSIDGMRETHDWFRKPGSFDETLNKISVIKNAGIKAVIMTTVSDKNMKE
                     VPEIIDTVVKYKADVFAFARYVPTCDEKSTGIAPFEYRNLLDACYKKFKSYEHDPACVT
                     WFNRKDHLWTLYEYEEGIWEIPEHATQGMIYGGCNCGNCHLTILPDGEVYACRRVSESK
                     VGNIFDDRLADLWIGKVEDYRQYQKFTKCTECELLAWCRGCPAVAKGTFGSFYAEDPQC
                     WKSHIESKEM"
     gene            complement(11182..11394)
                     /gene="acgA"
                     /locus_tag="LL065_RS19055"
                     /old_locus_tag="LL065_19030"
     CDS             complement(11182..11394)
                     /codon_start=1
                     /gene="acgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008753007.1"
                     /locus_tag="LL065_RS19055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_19030"
                     /product="ACGX-repeat peptide"
                     /protein_id="WP_226135829.1"
                     /transl_table=11
                     /translation="MKLNNLSGWNNETEKMAASSCGSACGASEPEKKPDSQPTACGSAC
                     GAAAPEEKPEQKPTACGSACGAGSK"
     gene            complement(11427..11996)
                     /locus_tag="LL065_RS19060"
                     /old_locus_tag="LL065_19035"
     CDS             complement(11427..11996)
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008980375.1"
                     /locus_tag="LL065_RS19060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_19035"
                     /product="flavin reductase"
                     /protein_id="WP_226135831.1"
                     /transl_table=11
                     /translation="MKKVSLGIKSAIFPTPVLMIGTYNDDGTVDVMNLAWGVMSASNLV
                     EINIMEKRKTTENIMKRKAFTVAMATVETMTESDYFGIVSGYKVSDKFAHSGFHATKST
                     YVDAPIIDEYPLTIECELKSIDKGPEELRILGEIKNVMVNEDVLGEDGKMDVSRLHAIV
                     WDNFKAGYYCVGEKVGQSFQEGRKLI"
     gene            12167..12634
                     /locus_tag="LL065_RS19065"
                     /old_locus_tag="LL065_19040"
     CDS             12167..12634
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025887.4"
                     /locus_tag="LL065_RS19065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_19040"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_226135833.1"
                     /transl_table=11
                     /translation="MSNKQAIIDKILKNEKAINERWNAGDYFGFLDCYIDDVTFVDPGI
                     PSMFQSREEVRKKMELKFPYKEFPIVKSEYSNEKVVVSDGEDMAVLTYNLHNYIQGKNG
                     KVLPLPLWHTTEVYQLIQGEWRIIHNHWSFAQVPELMDSVQAIFTELAKED"
     gene            13926..14567
                     /locus_tag="LL065_RS19070"
                     /old_locus_tag="LL065_19050"
     CDS             13926..14567
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LL065_RS19070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LL065_19050"
                     /product="hypothetical protein"
                     /protein_id="WP_226135835.1"
                     /transl_table=11
                     /translation="MALCFLCISYWCIGLTFNCRTTTAFGARGFSSYSADYVASLKSAN
                     IVILPDNDESGKAYANDVLSVIKNVVKSIKIIELPGLKPKGDIVDWVENGGTVDDLITL
                     VNKADEAVENASVQNKPIGNIYVDEFCYYKYYKKQVINISNFIINPKYYIENEGDTQII
                     GDIVTQEGVIGERTFKTSDFDDVLSFRRALNSFRTFYIGRVEDLQYIRFI"
     gene            14617..15774
                     /locus_tag="LL065_RS19075"
                     /old_locus_tag="LL065_19055"
     CDS             14617..15774
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LL065_RS19075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LL065_19055"
                     /product="hypothetical protein"
                     /protein_id="WP_226135837.1"
                     /transl_table=11
                     /translation="MFLKEKLKRSKIQYNHLLIEGESSSGKSSAVKYIITPILCMEDGI
                     LNAAQCTDFALNKTASSSNFIPLILEEYKPHIIGKYKVDLISGVMRNSYDNYKGIKGVA
                     TLDKNRSFIPRASVILSGEVGIEETANIGRSLRVIFATSYFDEVTKESLEKLKVNSILL
                     NKLGVSLLKEALKMSEKKIKEIHSEISEKLIGNDIKNDRVKNSIANCMIGIALLKRVFD
                     DFDLNMESCTGFAMKEIISSIERGAYEDLLDGGTSNKTVIEQNFETMNRMAANNELLRN
                     IDYDAVLDLDGDFVLRLNYTCFYDRFVKYCRDHNVTHEVLPLSSFKKQLSNMHYCKCYN
                     KPVNFSVRQENPKNKKTFRCAVVYISKLREKNVDVDFIADDNMID"
     gene            complement(15842..17254)
                     /locus_tag="LL065_RS19080"
                     /old_locus_tag="LL065_19060"
     CDS             complement(15842..17254)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011971366.1"
                     /locus_tag="LL065_RS19080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_19060"
                     /product="RNA-binding domain-containing protein"
                     /protein_id="WP_226135839.1"
                     /transl_table=11
                     /translation="MKVERIKEILNGGESITVEFKQSKNKLNKDVFESVCAFLNRNGGH
                     LFLGVEDKGGIVGINPEAIQKVKKEFVTSMNNPQKISPTFYLSVEEIEIEGKVVLYIFV
                     PESSQVHRCNGKIYDRNEDGDIDITDNTNLVSEMYMRKQGTYTENRIFPFAKISELKAE
                     LLIKVRKMAANEKSNHPWKSMNDLELLKSAGLFLKDRQSGREGITLGGILIFGNEELIH
                     AALPHYRTDAILRRVNLDRYDDRDDIRVNLLDSYERLMHFVSKHLNDNFYLEGDVRISL
                     RDKIFREVVSNLLIHREFANPFPAKLIIEKDRVFVENSNKSHGNGIIDPENFSPFPKNP
                     TIARFFKEIGWVDELGSGVRNIYKYNKIYSGAEPIFIEGDIFKTIIPLTLQVTMQATMQ
                     ATMQADEEVKVLLEYCKIPRSRSEMQGFMVLANRDYFRKNILNPLIKGGLLKLTIPDKP
                     TSPKQKYYSEKR"
     misc_feature    17296..17316
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.3"
                     /tool="antismash"
     misc_feature    complement(17297..17317)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.3"
                     /tool="antismash"
     misc_feature    17512..17525
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.34"
                     /tool="antismash"
     gene            17590..17775
                     /locus_tag="LL065_RS19085"
                     /old_locus_tag="LL065_19065"
     CDS             17590..17775
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LL065_RS19085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LL065_19065"
                     /product="hypothetical protein"
                     /protein_id="WP_226135841.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNIILIVPNKELESKAIAYKEEHFSCGETVINGSEMWDNMDSYP
                     EWLEMVTKNADVETYI"
     gene            17785..18111
                     /locus_tag="LL065_RS19090"
                     /old_locus_tag="LL065_19070"
     CDS             17785..18111
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024698.4"
                     /locus_tag="LL065_RS19090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_19070"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_226135843.1"
                     /transl_table=11
                     /translation="MTDTFFAMRQSDKKIIGIIDFRHSLNEFLKDFGHIGYSVCPLERR
                     NGYATEMLRQVLAIAKEQGLPEVFLSYMKGNVPSRKTILYNGGEYLRDFTFNNEVGEVF
                     RIVL"
     gene            complement(18797..19525)
                     /locus_tag="LL065_RS19095"
                     /old_locus_tag="LL065_19075"
     CDS             complement(18797..19525)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LL065_RS19095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LL065_19075"
                     /product="hypothetical protein"
                     /protein_id="WP_268064569.1"
                     /transl_table=11
                     /translation="MKSSKEELKKRGYIENDDITNDYKLLTLDELCVLLESKKAFERTI
                     AIRLLENCNNILQLDLGIILLETLVKEKSLYTKIEICNALEKGDSEIAKQMLSYVGKIG
                     KNQHVKLPNEVSQKISYPLPRDIIARVMGKMNKSVLPILVEALNDYDVFAIREVIDGIG
                     FLCFYNDIPNECFVVKKLIKCYEEYKDDYILRWKITMAFSAFNNEFATSELKKIIRNDN
                     EELIIKEAYRALKLIEKRCK"
     gene            complement(19739..20278)
                     /locus_tag="LL065_RS19100"
                     /old_locus_tag="LL065_19080"
     CDS             complement(19739..20278)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024783.4"
                     /locus_tag="LL065_RS19100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LL065_19080"
                     /product="HNH endonuclease"
                     /protein_id="WP_226141147.1"
                     /transl_table=11
                     /translation="MVQYKAPLILNNNKILWSYIDKIENKQKVDEIEKKEVEKIIELDK
                     ILSRTLGVTEKDALIKIRIGQGLFKKKLEMIECQCKICGLKSKKLLIASHIKPWKDCNN
                     NERLDDNNGFLLCPNHDALFDKGYICFGDDGKIMVSKLIEKDCYKLLNISSSDQIALTD
                     KNKGYLKWHRDKIFKR"
     gene            complement(20244..20585)
                     /locus_tag="LL065_RS19105"
                     /old_locus_tag="LL065_19085"
     CDS             complement(20244..20585)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LL065_RS19105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LL065_19085"
                     /product="hypothetical protein"
                     /protein_id="WP_226141148.1"
                     /transl_table=11
                     /translation="MSYNVISAFKELNELDWGTDKNVIKGDYVYIYLVAPIKKIILKTK
                     VVIDNIGENEFIDDSKFMLKEITKSEKTKYIRLKLITSFSDNISNMLTYEILRQNGLNG
                     PIQGTSYFK"
ORIGIN
        1 tccccatcag ttccaaggaa gttgccatag aagacgttaa gcaactcact gctaagtaat
       61 gcgtcggctg ctgccttcgt cctaatagat tgtccagtct gagcaagatc agctgtagtc
      121 gataggcata ttgccgctgc tggcaacttg ataccattct ccctcagtga tagcaatgtg
      181 gacaatgtca atccacctcc agctgaatct cccgctatga taatgcgagc aggatccaca
      241 ttttgagcga gcagctactt gtagctttta agtatctcct atatgcttcc acttgtttaa
      301 accttcctaa tttaaatgct acctttcata ttaaccatgc ttattttttt atatcacccc
      361 attgccagca acgtcattgc ctcaagttgc cttcccgtta gttagatgat acagactttt
      421 ttcagcctgt cggctcagca tacatgatag acgtgcaaaa taaactattt ttcttagctt
      481 ctaaataatc attaaaaagc caaactgcta ttttattttt ttatcttatg attccatact
      541 cccccaattt ctctccttca aagattacca ttttatcaag tctattggtt agagatttaa
      601 tttaacactt cttttttatc tttgcagtta tattctccct tagctttcct atcagcaatt
      661 ttttctataa aaaataatat ctgatttgct attaaggcca aaccagccgc cataatagta
      721 ccccacaaga tttttattat ataattcatt cttagtccat caaataatat aacccctaat
      781 ccaccagcat taattacgga tgcaatagtg gctataccaa tagttgatac aatagctatc
      841 cttgttcccc caattattat tggtccagct aaaggcaatt gaatatctat aaatagctgc
      901 ctagaattaa atcccatacc ccttgcagcc tcaataattg aagtatctat tgattgaaag
      961 gccattagta tattccttac aagtatatat tgattgtata ttataagaac tatcacagct
     1021 gtcttttctc ctaaacctaa aacaggaatt aaaaatgcaa acattgcaag gctgggtatt
     1081 gaatacaaca ctccaaacaa agatagtaca atcatagaag cccatcgcga atgtaagagt
     1141 aaacttccta aagctattgc aataaataaa gatattgcaa cacttattac taccaaatga
     1201 acatgctgca ataacaatgt aagcatatcc tcataatttt caaatagata tttaatcaca
     1261 atcatcacct ggcttctcat aaatatcttg tctttcccgt acaccctcaa tattcagctg
     1321 actccaattt atttttccta taacacgatg tttgtcatcc tcaactataa ctgttttaac
     1381 attattatta aggaaagcag ttaacacatc atataaactt tcttcttttc caactcttac
     1441 gccttcatga ttcactggta actctaacgg aatcatagca agttctgcct ttaaatattt
     1501 caacttttga agggcatcct ctgaagagac caaacgagca acaaaatcat ttgcaggttt
     1561 aaatagaata ttataaggac tatcaaattg ctgaatcttt cctttatcca ttacaataac
     1621 cttatcccca agtttaaaag cttcattaac atcatgcgtt acaaaaacga ttgtcttatt
     1681 aagctttttt tgtatactga ttaattcatc ctgaagattc tgccttgtta tagcatcaat
     1741 agccccaaag ggttcatcca ttaacattat atctgggtct gcagccattg ccctcgctag
     1801 accaactctc tgctgctgtc caccagataa ttgcctaggg tatcttttct taaattcatc
     1861 tgtagaaagt cccaccaact tcaataaata ctctacacgc tcagttattt tattattatc
     1921 ccaatgtaac attttaggta ctgttgctat gttttgttcc acagtcatat ggggaaataa
     1981 tccaatctgt tgaataacat agcctatttt tcttctatgt ttctctacat tcaaattttt
     2041 tatattctca ccaaaaaaca atatctcccc agaagtagct tcatataatc cattaatcat
     2101 tttcattaat gttgttttac cggaacctga agttcctaaa acagttatga aacttccttt
     2161 ttcaatactt aaactcactt ctgaaacaga atactcttta gaattattaa attttttact
     2221 aaccttaatg aactcaatag ctgttgtcaa tatttatgta cctcctatat ataaataagg
     2281 taacttcttt tcctcctctt aataaaggta aaaaacaagc tacctattta aattacaaat
     2341 ttctatttac caaactcttg attgtaaaat tcctttgcta cagttttata ttcttttttg
     2401 tctatgtcta cttctgcatt taattttatt aaagttttat tatccaattt agcagtaact
     2461 ttatttagaa tatcttttat gtcagaattc ttaacaagaa tatcttgcct aactactgga
     2521 gcaacattat atggcggcca tacatgtttg tcatcctcta aaactacaaa ctgactatca
     2581 cttaattgac cttctgtggt gtaagctaca gcaagatctg ctttatcatt tttaagtaca
     2641 tcatacttta agccattatc atataatttt tcatccttaa aattaaatgg tccatatgcc
     2701 tttattaaag cttgaagccc atctgacctc ttatcaaatt ctccctgaga ggcaaatcta
     2761 atttgacttg cattcttttg caaatcagaa attgtatgta cattatactg atctgatgcc
     2821 tttttactaa taaccaatcc ttgagaatca ttagcagcag atggagctag ccaaattaat
     2881 ttaaatttat ccttgtattt tgcagaaact tcatcataaa ccgcttttga atcatacatt
     2941 ggtgcttctt ttaaaatcga taataaccca gtacctgtgt attcaggata taaatctata
     3001 tctccattta ccaaagaagt atgaactaca gcatctccta aattcaattt tctatcaacc
     3061 ttatatccag catgttctaa tgcatctgca tataattctc ccaaaaccag agattcagta
     3121 aagttctttg aaccaacctt tattgtcggt ttagaaaccg aaccattagc agtattagga
     3181 ttagagccag tgcttttact gcaacctgca aatatcccag cagtaagcac tatcgctaac
     3241 aacggtaatg caaaaaaaat tttattcaaa ttgaacactc tcctaaataa ttaattttaa
     3301 tttctttgat atcttgtaat tccttgttgt aaaaaaaata atattatttc tgcaataaca
     3361 gataaaattg ctactgatat tcctcctgta agaagcatgg cataatcatt catgcttaat
     3421 ccagtaaata taaaatcgcc taatccccca gcaccaatat aggctgccaa agtagcactt
     3481 gatataactt ccacagaaga agttctaact cccgtaatta tcaaaggcat tgctagtgga
     3541 agctggactt taaaaagtaa ttctctataa cccattccca ttccctctgc actttcaata
     3601 attgatgggt taatattttt aaaacctaag taagtgttaa taagtattgg aggtactgca
     3661 agaattatca aagcaactaa cgcaggagta aaacctgttc caagtatcgg tattgccaaa
     3721 accagtatag caagacttgg aacaaccctt agaaaattaa aaaaattcat tacgggatag
     3781 agaacctttg aactttttga gcataatatt cctaaaggga cagctatggc aatgcttatc
     3841 aatacagctg ttatacttat ggatatatgt ataagaacag ctgtataata ttgcttgata
     3901 ttacttagta aaaatttaac aatttcattt aacattaaat taatgtacat cctttccaaa
     3961 gatttagatt aaacgcctct ccccatttct tctgccagct ccaacacacc tgagctctct
     4021 atagctcctt tgccatccac gccgcccgtc tgcaatatcc cacggtcttt ccatccaagg
     4081 aactctctca tcaattcata catcttgatg actggcttat actcttcttt gtccgctagc
     4141 tcaccacata tgaaaatttg aaaatctcct gatacttaaa taaccacttt cggttttttt
     4201 acattagggg agaacggtgt gattaaagcc catgtagaat gaatgacatg ccagccactt
     4261 gcgtctttct ggaaaatctc aataacgttg taatgcattt caatcataga ggtgtccgca
     4321 tgaagctgga aagtcaggat tgctatatct tcaccgaact gaactctcgg agcatggaaa
     4381 tcgtagctat cagcatgcat gtttccttcg acgacagtct tcagaaaatg tgcaacttct
     4441 tcataagtat ctgatctctc ttcagtacct gcatcaaaat aagtgaagtt gtccttggac
     4501 cagagatcta gataaccgga catatcgcct ttgaaaaact tatccagtgc aaccttttcc
     4561 attcctataa tttcttctgc taacttctgt tgctcaggtg tatagcgtgc ttcataaaat
     4621 ttcttatcta ccattgtttt acctctttct ttttataaat tatatacaag actaaagaaa
     4681 aattatcata cattatttga tactggatac ttcctttaga attgttgaag ttgtataatc
     4741 attttagccc aacgaacaga atgggtaaat gttaaatcaa aacttttact gatacttttc
     4801 ggacatttat ataattttag aataaaggcg tttatgtact gttctagtct tatatatatt
     4861 tctacaaagc taaatatgca tctgttaaca tactcagaca gttgttccgc catataagaa
     4921 gattaaaatt tatccagttt catataacca tacatatcag taaaccccgc tttttcatat
     4981 aatcgtcttc ctgaatctga tgtttccaga tagattttcg ttataccttt ctgcttagcc
     5041 tgttccacca gccaatgaac cactttttca ccaactccag agttacgaaa ctgtggacgg
     5101 gtataaatat tcattaaata agcacattta cctgttggat tatccggtga gggcatctcc
     5161 ttataaacac acatacctcc acaacctata atctcatctt tcttccatgc aaagcaggat
     5221 aaatgtcctt catttagtaa catttcttta taataattgt ggtttgcttc cgtcagttcg
     5281 ctcatttgca tatcctttgg tacagaaaag acttcacgaa gaacttccat tcgccattcc
     5341 attaacgtat ccaaatcttg taattctgcc ttacaaataa tcacttccat tataaatccc
     5401 cagcttttag tacaactggt aatgctcctg aatccacctt accattcggt gtaagtggca
     5461 tattggcgat ctgtataaag aatttcggta ccatataggc atgaggatgt ttttccatac
     5521 tctttctgat tttggaaaca aatgaacgag taccattcgc aacaacatat gcaactatat
     5581 aagacagatt ctgctcatct atataaggct ttgctttagt cattctatca agttctctac
     5641 gtgtgatagc ccgtctttca tctaacaccg ctgtatgttc tggatttctt acaacctgct
     5701 cttcaaatac cttaatatta cattttcttt gtccataaaa ttttcctcca ctatttttta
     5761 attttcttaa tcgtccaata aatcattaac ttacctttgt atattcatta tactaacatt
     5821 aaaataacaa tccaacgcta caacagcttc cattagacat ccaactgtct ctccttccga
     5881 tgggtacgga cgacagttgc tgtaagggct tctttataac tcacaagaga atccggcata
     5941 tcacgatcaa cagcgatctg ccgaagatga tgcagcgaat cgtcctggca catgagatcg
     6001 gacacgccgt cctgcatgca aaatcaggag cacttgccaa atttcaagat atgttagtat
     6061 tagatgctgg cgatactact gaaaacgaag ccaacccctt tgcttcgaag cttttgctcc
     6121 gggataaaga tgtcatggag gctctgaaca gcgactgcta cttcaaccag gttgccgctt
     6181 ccctatacgt accggcagag atgctggact tcaaattccg cgtgatgaag cggaagggct
     6241 ttgcgctgaa tgcgccgtat attgcgcagg gtaatttctt gaaggatttt gagaagacga
     6301 ttcagtattg cccgaatgat atctagtcta tacccggcag aacattttca tcctgctggg
     6361 tatttattat attgtcacat tcccacatat tgtgcaattt tcttcccctt attcctcctt
     6421 cagctttttc ccaactgaaa aggcttttcc cgctacatct cccatcagta cataatcctt
     6481 atgtgtgtct tcaaaccaga cgatgcccat ttttctgaaa tccggcagat tatcatttcc
     6541 aagatatcga tcatctatcg tagtttcctt gatttcacca acaatccgcg tgttaccaaa
     6601 ttcttctgta atagagatta catcacagtg aaatgtcata gggtattctt cgaactccgg
     6661 cgcatttaca tagtcagact gtctgcaggt caatccggat ttttcaatct tattgggggt
     6721 ctttgcagct gagactaatc caacataatc agaagccacc atagtatctt ttgtgacaaa
     6781 agccatagta aatgctttgc tttccttcaa attatcaagc gtcttatgct tgaggatatt
     6841 gattgccact tcctttgaac caacttgcat agcccagccc acattcattg cgtctgggtt
     6901 cccattctca tcataggttc caatcacaac agatgcatat ggcacaagtc cgattttggc
     6961 tccaaatttc ttcttcatct tgatatctcc tctcatgttc atttaattcg tttatcattt
     7021 tcttatacct accttgtgtt ttttctcgct ttacaggacc accacatgtt ttccgataaa
     7081 ttgaccagac tctaagtttg cttgtgcttc tccaacctct tccaaaccct gatagacttt
     7141 tgcaattggc aatttacttt caccctcttc gatttttctt agaatgtcat ttaagatggg
     7201 gcttggcaaa tcggaaacac ctcccgcata ggaagtgaaa tactttccaa atggaatttg
     7261 ataaggcgaa aaattgtcaa atgtccaagt gttattaagt gcacctgtaa agcagagctt
     7321 accggcagct tttaagagag ccatgtcctg tggcactaca ttcgttccaa ccagctctaa
     7381 gatcttatcc actcccctag gtgctatttc tctgactttg tctgcaaagt ccttgtcatc
     7441 aagaatcgga aaatctaccc caaaggattt gagggcgtca aatttatcca gctttcgact
     7501 ggtcgaaagg actgtggcac ccatggattt agcaaggaca gcagccgtta ttcccacagt
     7561 agaggtccct ccgtgaatca agagggtatc gcctttttta agatttaatc ctgttgtcaa
     7621 tgatccatac gccgtctgaa ccatttccgg tacagcacct aaaatttccc aaggaagctt
     7681 actttcaaat gcgataagat tggactctgc aatcaacatg tactccgcat aagagccatc
     7741 aatagcccgt cccaggcctg acatcatggt tgccacctgt tgacctactt ttagttgact
     7801 atcctccgct acttcttcaa taactccgac accttcaatt cccaaaatac gaggatagga
     7861 aaaatccgct gaagataatc cttttcggct agtaacttcg gactcattaa ctccgaaggc
     7921 cttcaccttt accagggcat ggcccggttt cacctccgga cgattaacag ctgttggctt
     7981 gagttcctct atactacacg cttgtgtgag acggattgct tgcatttctt gattcataat
     8041 gtaccttctt tctcttatac tgattaccac ttgtaatgag aggtgcgcag cacctcaaat
     8101 ctgagggggc taaatagtca ccttattatt aagttgttgg aatgccctct atatacttat
     8161 tatacttaca tcacaatagc aatcaagtac gcagaatatt tatacatagt attagaaagt
     8221 gtactaatgt acaatcaata tctgattgat tgtataaata tttaaggaaa tttctatcct
     8281 catgcccaac taatttttta taatattaca taataagata aaataaaatc gccaaatctt
     8341 aaagctaaac aaaataaatc cttcaaagag gctataaatt gtaataaact tcaaaaccac
     8401 gaacttcagg agaatcaaaa tttaaaagtc aagaccacct gtagttactt aaatcctttt
     8461 gctataccta tatccgcatt gatacaaagt aatttccagc gcatttcctt tggtgcagat
     8521 gcttatccac cattgataca aacatagaat tcgtcttcca atctcttatc atttcctgat
     8581 tacttttcat cttagtaata tatttaaaca gatcaactcc tttgtacgcc attggttagg
     8641 tatagttcat tatgtaagaa cgcaaaggac tgaccgcgca ggaatagaaa gggtcgattt
     8701 accacatgct acacttctag agtatgaggc agtagcaagc acccagcaat tattaatata
     8761 agccataagc gtttatgtaa ttgtgcaagc gttgaaacac gtcaaacatg gcaagagttc
     8821 ttattatcat ttgaagataa agaacgagac catataatgt atgagtatct gcttttatat
     8881 accgtggcca ttgttatgag tataagtcat gtggatatca taagactgag gcatacaaga
     8941 aaaaattaaa agcatatagg gagttgaacc atcacaaaga tcaagtacaa aaagtatgtt
     9001 gaggtatacc ttgtcgttgt cgaaactccg ttggtgtgca gccagtttcg cgcttgaaga
     9061 atttgctgaa gtgagtggcc tcttcaaaac caagcttttc cgcaatgacg cagataggga
     9121 agtctgtatg taccaacaaa cgcttcgctt caagatttat acgtgcggcg atgaaagatt
     9181 ttgcactcac tccaaccgct gtcgtggttg cgcgcgtaag actcctttcc gtgcaatggc
     9241 agccatcagt tatgaacata ataactattg atctaatatc gtagtaaaaa acagtgtgta
     9301 gtttgaaaat ctcctgatac ttaaacaacc actttcggtt tttttacatt aggggagaac
     9361 ggtgtgatta aagcccatgt agaatgaatg acatgccagc cacttgcgtc tttctggaaa
     9421 atctcaataa cgttgtaatg catttcaatc atagaggtgt ccgcatgaag ctggaaagtc
     9481 aggattgcta tatcttcacc gaactgaact ctcggagcat ggaaatcgta gctatcagca
     9541 tgcatgtttc cttcgacgac agtcttcaga aaatgtgcaa cttcttcata agtatctgat
     9601 ctctcttcag tacctgcatc aaaataagtg aagttgtcct tggaccagag atctagataa
     9661 ccggacatat cgcctttgaa aaacttatcc agtgcaacct tttccattcc tataatttct
     9721 tctgctaact tctgttgctc aggtgtatag cgtgcttcat aaaatttctt atctaccatt
     9781 gttttacctc tttcttttta taaattatat acaagactaa agaaaaatta tcatacatta
     9841 tttgatactg gatacttcct ttagaattgt tgaagttgta taatcatttt agcccaacga
     9901 acagaatggg taaatgttaa atcaagactt ttactgatac ttttcggaca tttactagtt
     9961 attgtatttc atctcggcaa cctgcacccc ttcattgcct ttacatttct ttgctttcta
    10021 tatgactctt ccaacattga ggatcttctg catagaaact tccaaaggtg cctttagcca
    10081 ctgctggaca acccctacac catgccaaaa gctcacattc ggtacatttg gtgaactttt
    10141 gatactgcct gtaatcctct actttaccaa tccacaggtc cgcaaggcgg tcatcaaata
    10201 tattccctac ctttgattcg gacaccctgc ggcaggcata tacctctccg tccggcaaaa
    10261 ttgtcagatg gcaatttccg cagttgcagc cgccataaat cattccttgc gtagcatgtt
    10321 caggaatttc ccaaatgcct tcttcatact catacagagt ccaaagatga tccttccgat
    10381 tgaaccaggt cacacatgcg gggtcatgtt cgtaagattt aaacttttta tagcaagcat
    10441 ccagcaggtt tcgatattca aacggcgcta tcccagtact tttttcatcg caggtaggaa
    10501 catatctggc gaacgcgaat acatcagcct tatacttcac cacagtatcg ataatctctg
    10561 gaacctcttt catattctta tcggacaccg tagtcatgat aaccgccttg atcccagcat
    10621 tttttataac tgaaatttta ttcagcgtct catcaaaaga acctggcttg cggaaccagt
    10681 catgggtttc cctcatgccg tcaatggata gctgatattt ttcacagcca cagtcatgca
    10741 gtctctggca gactgcttct gtcaaatgaa atgggttgcc cagaatcgta aaaggtatct
    10801 gcttttcttt taccagatcc atcagtttcc agaaatccgg atgtagaatt ggatctcctc
    10861 ctgtaatata caaatatggc agtctaccat atgttttaca aaaatcttct atgttgacaa
    10921 tcgttttttt catatctttc cattccatag aaatgatatt tttttttgta ttctcagcaa
    10981 aaatataaca gtgcttgcac cgttggtcac aatcttctgt aatatgccat tgaaaagcaa
    11041 aatactgttt catgtcatgt tcctccaaac tttaaccacc aaccagaaaa tctgccattg
    11101 gtgacttttc gatatattta gtaaatagaa aaccgttgcc aatcacgaca acgattctcc
    11161 agcttatctc gcaatatccg attacttaga accggctcca caagcacttc cacaagctgt
    11221 aggcttctgc tccggctttt cttccggtgc tgccgcacca caagcagaac cgcaagctgt
    11281 aggctgtgaa tcaggctttt tctccggttc tgatgcacca caggcagaac cacaagatga
    11341 cgctgccatt ttctcagttt cattgttcca tccagataaa ttgttaagtt tcatttttct
    11401 ttcctcctca tgatttaaaa aatatatcag atcaacttcc ggccttcctg gaagctctga
    11461 ccaacctttt cgccgacgca gtaatagccg gccttgaaat tgtcccacac gatggcgtgg
    11521 agtctagaaa cgtccatctt tccatcttcg cctagcacat cttcgtttac catcacattt
    11581 ttaatctctc caagaatgcg aagttcctct ggccccttat cgatgctctt gagctcacac
    11641 tcgatggtca gcggatactc atcgattata ggagcatcca catatgtgct ctttgtggca
    11701 tggaaaccgg aatgtgcaaa tttatccgaa actttgtagc cggacacaat cccgaaataa
    11761 tcggattcgg tcatagtttc cacagttgcc atagccacag taaacgcctt acgcttcatg
    11821 atattctccg tcgttttgcg tttctccata atattgattt caaccaagtt acttgcactc
    11881 ataacgcccc atgccagatt catcacatcc acagtaccat catcgttgta tgtaccaatc
    11941 atcaacactg gggttgggaa aatagcagac ttaattccta aactaacttt tttcatggct
    12001 ttattcctcc ttattagatt tgtatttgcc tttcggtatt tattgtacta cttctaaaat
    12061 ccaaaacaag tacgcagttt attttaactt tgtatcaaaa aacgtactac ttgacaattt
    12121 ttctttagtt ttgtattatg aaagaaaaaa tgaaagaggt aaaataatga gtaataagca
    12181 agctattata gataaaattt taaaaaatga aaaagcaatt aatgagcgtt ggaacgcagg
    12241 agattatttt gggtttttag attgttatat tgacgatgta acctttgtag accccggtat
    12301 tcctagtatg tttcagagtc gtgaagaggt tagaaaaaaa atggagctta aatttccata
    12361 taaagaattt ccgattgtaa aatctgaata ttctaatgaa aaagttgtag taagcgatgg
    12421 agaggatatg gcagttttaa cttataacct tcataattat atacaaggga aaaatggaaa
    12481 ggtgttacca ttaccgcttt ggcataccac agaagtttat caacttattc aaggtgagtg
    12541 gagaataatt cataatcatt ggtcttttgc acaggtaccg gaattgatgg atagtgtaca
    12601 ggctattttt actgaattgg caaaagaaga ttaagttaaa aaaattgatt tataaaatta
    12661 gttattaaaa agtttggctc agaatgtaaa tttttgagcc aagctttttt tatagttttt
    12721 ttccaacggt ataatcacgt ttcaatatta gatgctcttt aatgtcatct cggtcagtga
    12781 cacctcctgc aaatatgatt tcagttagat gagttttttc aaagcaacgc acccgtttat
    12841 tgttccttgt gcggttgatt ctttatcttc aacggctgct gccaaaaggt aaatatctcg
    12901 aataatatat tttcataact gtttgttatg aattttatca cctcatttgt aaaaaaacga
    12961 ttaaagaagt gcataaatta aggatttcta tatagttttt cgttgtagca atacgcaaat
    13021 ctccacatgc cttgtattcg caagcatatt aatttttatc ctcccaagcc ctattcacat
    13081 caaccctata cccatcagga gtcacacaat ccctatacat ctttcgtatt catgaagaac
    13141 atctcctttg gttattgttt gtcgtgactc aattatacca aataagggaa tgttcttcta
    13201 tatttttgac ctttaatact gaaattgcat ctataaatga attatggaag gctgaagaat
    13261 gatgaaaaag gtaaccctaa tattaaaaaa ggtaacccta atattgaaaa aataaaactt
    13321 atttaatatt ggggaaatga acttattatg aattaggtta tatattggta agtgaatttc
    13381 tttctggaaa ggtagttaaa catgatgtta cctacagttt tgctaataaa aaacaataac
    13441 aattaaaaaa ggaggaacaa atttgaataa attaatgaaa acaaccatac tttctagttc
    13501 cttagttaca gtcatggctg gagcagcggt ttctcctgca ttatgaacaa ttgcattagc
    13561 ttttcctaat actaatccag tgcttataaa aatgatactt acgataccag ctgttttaat
    13621 aatatttttt agtttattat caggaaaact aaaggaaaaa tttacaaaga aaagtatttt
    13681 aattgttgga ttgatttttt agttggtgga ttcggcggtt cttttgcgaa tagtatttat
    13741 ccactattgt ttagcagagt tgttttagac atgggagtcg gtctaatatt tcccctttca
    13801 actgcactta tcgcagattt cttttcaggt gacgaaagaa taagtatgat gggcttttcg
    13861 caagcatctt ctaacttagg tggaataatt actacaattc tttcaggggt attagccaaa
    13921 ttaagttggc gttatgcttt ttatgtatat cttattggtg tattggtctt acttttaatt
    13981 gtagaactac cactgctttt ggagctaggg gattttcatc ttatagtgca gattatgttg
    14041 cttctttaaa gtccgccaat atagtaattc tacctgataa tgatgaaagt ggtaaggctt
    14101 atgcaaatga tgttctaagt gttataaaaa atgtggtcaa atctataaaa ataatagaac
    14161 ttcccggttt aaaacctaaa ggtgatattg tagattgggt ggaaaatgga ggcactgtag
    14221 acgatttaat aactttggtt aataaagcag atgaagcggt agaaaacgcc tccgtgcaga
    14281 ataaacctat aggaaatatt tatgtagatg agttttgtta ctacaaatat tataaaaagc
    14341 aggtaattaa tatctctaat tttattataa atccaaaata ttatattgaa aatgaaggtg
    14401 atactcaaat tataggtgat atcgttaccc aggaaggggt tataggcgag aggactttta
    14461 aaacttccga ttttgatgat gtattatctt ttagaagagc actaaacagc tttagaactt
    14521 tttatatagg aagagttgag gaccttcaat atataagatt tatttaaatt tagtatactt
    14581 aaaaatactg cagccatatt aggttatgta tgtggtttgt ttctgaaaga aaagcttaaa
    14641 cggagtaaaa ttcaatataa ccatctttta atagaaggtg aaagcagtag tggtaaaagt
    14701 agtgctgtaa agtatattat tacacctata ttgtgcatgg aagacggaat attaaatgct
    14761 gcacaatgta cagactttgc cttaaacaaa actgccagca gcagtaattt tatacctctt
    14821 attttagaag agtacaagcc tcacataata ggtaaatata aggtggattt aatatcaggg
    14881 gttatgagaa attcctatga taactacaaa ggaataaaag gagtagccac cctagataaa
    14941 aatagaagtt ttattcctag agcttcagtg attttatctg gagaagtagg tattgaggaa
    15001 acggcaaaca taggaagaag ccttagagtt atatttgcaa cttcttattt tgatgaggta
    15061 accaaagaaa gtctagaaaa attaaaggta aattccattt tacttaataa acttggagtc
    15121 agtcttttga aggaggcctt aaaaatgagc gagaaaaaaa tcaaagaaat ccatagtgaa
    15181 atttcagaaa aactaattgg taatgatatt aaaaatgata gagttaaaaa ctctatagct
    15241 aactgtatga ttggtatagc tttacttaag agggtatttg atgatttcga tttgaatatg
    15301 gaatcgtgca caggttttgc tatgaaagaa attatttcat caatagaacg gggggcttat
    15361 gaggacttgt tagatggagg aacatcgaat aaaacagtca tagaacaaaa tttcgaaact
    15421 atgaatcgta tggcagctaa taacgaactt ttaagaaata tcgactatga tgcagttctt
    15481 gatttagatg gagattttgt tcttcgcctt aattatacat gcttttacga taggtttgtg
    15541 aaatactgta gagaccataa tgtgactcat gaggtgttgc cactgagtag tttcaaaaaa
    15601 caattaagta atatgcacta ttgtaaatgc tacaataagc ctgtgaattt ttcagtgaga
    15661 caagaaaatc caaagaataa aaagactttt aggtgtgcag tggtttatat tagtaagctt
    15721 cgcgagaaga atgttgatgt tgattttatt gcagatgata acatgataga ttgaagaaca
    15781 taatgattaa ggcgatgact ggatgtcatc gccttactat aaattatttg aatatgatgt
    15841 attatctttt ttcagaataa tatttctgtt tggggcttgt cggtttatct ggtattgtta
    15901 attttaataa cccaccttta atcaaagggt ttaaaatatt ctttctaaaa tagtctctat
    15961 tagcaagaac catgaatcct tgcatttcac ttctgcttct tggtattttg caatactcca
    16021 ataaaacttt tacttcctca tcagcttgca tggtagcttg catggtagct tgcatggtaa
    16081 cttgcaaggt cagcggaata attgtcttaa aaatatctcc ttcaatgaag ataggctcgg
    16141 cgccagagta tatcttattg tatttataaa tatttctgac tcctgatccc aattcatcca
    16201 cccacccaat ttctttgaaa aaccttgcta ttgttggatt ctttggaaat ggtgaaaagt
    16261 tctccggatc aatgatacca ttaccatgag acttgttgct attttcaaca aaaactctat
    16321 ctttttcaat aattagcttt gctggaaatg gattagcaaa ttctctatga attagtaaat
    16381 tagaaacaac ctctctaaaa attttgtctc taaggctaat tcttacatct ccttcaaggt
    16441 aaaaattatc gttcaaatgc tttgaaacaa agtgcatgag acgttcataa ctatctagta
    16501 gattaacccg aatatcatcc ctatcatcat accgatccaa atttactctt cgtaaaatag
    16561 catcggttct ataatggggc aacgctgcat gaatcaactc ttcatttcca aaaatgagta
    16621 taccaccaag agttatgccc tctctaccac tttggcgatc tttaagaaat aggcctgcac
    16681 tttttaaaag ttctaggtca ttcattgact tccatggatg atttgatttt tcatttgcag
    16741 ccatttttct aacttttatt aaaagttcag cctttagttc cgatatcttc gcaaatggaa
    16801 aaatacgatt ctctgtatat gtgccctgct ttctcatgta catttcagaa acgagattcg
    16861 tattatcagt aatgtcgata tctccatctt catttctatc ataaatctta ccattacacc
    16921 tatgaacctg agaactctct ggcacaaaga tgtaaagaac cactttccct tcaatctcta
    16981 tttcctcgac agataaataa aaagttgggc taattttttg aggattattc atagaagtca
    17041 caaactcctt cttaaccttc tgtattgctt ccggattaat tcctacaata ccacctttat
    17101 cttcaacacc aagaaatagg tgtcctccat ttcgatttag aaaagcgcat accgattcaa
    17161 aaacatcttt atttaattta tttttactct gcttgaactc aacagttata ctttctccac
    17221 cattgagaat ttcttttatt ctttcaactt tcatatatat caacttccac tctaaatttt
    17281 ttatttaaac cctgtaaata tatcatataa tatattttat ctaatttcaa acaaagcata
    17341 caaatttctt caaagtaaaa aatgaatcca cccatatttg ccatactatg ataagtaatg
    17401 ctccaattcc atacaatatt ataagtgtca gatatatacc attaaattta taatctaaga
    17461 caatttacca tgttttacaa ataaaagatg attatacata taaaaatatg ctataattac
    17521 tattaattaa gacggcatta tattttatta caaagtaatg attatttgca taatattagg
    17581 aggtcaaatg tgaaaaacat aattttaata gtaccaaaca aagaactgga aagcaaggca
    17641 atagcctata aagaagagca cttttcctgt ggggagacgg taattaatgg aagcgaaatg
    17701 tgggataata tggatagtta cccagagtgg cttgaaatgg ttacaaagaa tgcagatgtc
    17761 gaaacgtata tctagggttg ggtattgaca gacacctttt ttgctatgag acaaagcgat
    17821 aagaaaatta tcggaattat agattttcgt cattcattaa atgaattttt aaaggatttt
    17881 ggacatatcg gatacagtgt atgtcctttg gagcgtcgaa atggttatgc aacagaaatg
    17941 cttcgtcagg ttcttgctat tgccaaagaa caagggttgc cagaagtgtt tttatcttac
    18001 atgaaaggta atgttccttc aaggaaaact atactgtata acggtggaga atacttaaga
    18061 gattttacat ttaataatga agttggcgaa gtgttcagga tagttttata agatttgtga
    18121 gtataatgaa tggttgtgtt aaatcgcaat tttctttaag tcttcatcaa tcgtaaaagt
    18181 gcgatatatt caacattgta attaactgcg tcataatggt attataaagc gaataaaaaa
    18241 tgaatttaaa agagggggga ttaatattac atttttcaat aagtataaat taagaatttt
    18301 aatgatgata ttatttattt ttggaattat aggacatgta tataaaatag acttaattgc
    18361 tggtttatgt gatacaattt ttttatcatg tgtattatac atatacatta aaaatgacat
    18421 gatgaaagca ataataaaaa ttttcagtat tatatattta attggtcaag ttatagctta
    18481 tggatttaat attgagggtt taaagacgta tgttagcttt aataacggta atggaacaac
    18541 tactagtata gtgagcacag ttttcccttt aatattggca tttataagct actatatatt
    18601 tcaattattc aataaaaaaa ataaaattta atttcgtaat attcttctac cacgtcataa
    18661 ctgaacacac gattttccat aaaccattgc atttatatgt taaacgaagc attgatttat
    18721 atagattatt aagcaattaa gtttttgaat atatcatttt atttgatata aggaaaccaa
    18781 aaatggattc cttgaattat ttacatcgtt tttcaatcag ttttaatgcc ctatatgctt
    18841 cttttatgat aagttcttca ttatcattac gtattatttt ttttagttca gaggttgcaa
    18901 attcattatt aaaagccgaa aaagccattg taattttcca acgaagaatg taatcatctt
    18961 tatattcttc ataacacttg ataagttttt taacaacaaa acattcatta ggaatatcat
    19021 tataaaaaca taaaaatcct ataccatcaa taacctctcg aattgcaaaa acatcataat
    19081 cattaagggc ttcaactaat ataggcaata ccgatttatt cattttcccc attacccttg
    19141 ctataatatc tcttggcaaa ggataactta ttttttgaga aacttcatta ggtaatttaa
    19201 catgttgatt tttccctatt ttccccacat aactaagcat ttgtttcgca atttcactat
    19261 cacctttttc taatgcatta catatttcta tttttgtata gagagatttc tctttcacaa
    19321 gagtctctaa taaaataatg cctaaatcta attgcaaaat attattacag ttttctaaca
    19381 gccttatagc aatagttctt tcaaatgctt tttttgattc taacaaaaca cataattcat
    19441 caagtgtcag taacttataa tcattagtaa tatcatcatt ctctatataa ccacgttttt
    19501 tcaactcttc cttactactt ttcattctta ctccttattg tttattaatc ataattctat
    19561 gatttataaa ccttatccta atattgtgtc cgcatttaat tgtacaacat agtaatgtaa
    19621 ttattcaaat atttaacata gttatatgta tattgcttcc ctatttttaa actcctttaa
    19681 ctttgtatca gaatgagatg tatgcgactg gactataaat gttatcttaa atttaaccct
    19741 atcttttaaa tatcttgtct ctatgccatt ttaaataacc tttattttta tctgtaagcg
    19801 caatttgatc actgctacta atatttaata atttgtagca atctttctca atcaatttag
    19861 agaccataat tttaccatca tctccaaaac atatatatcc cttatcaaat aatgcgtcat
    19921 gattaggaca taataaaaaa ccattgttat catctaatct ttcattatta ttacaatctt
    19981 tccatggttt tatatgactt gcaattaata attttttact tttcaagcca caaattttgc
    20041 attgacactc aatcatttct agctttttct taaacaatcc ttgtcctatt cttattttga
    20101 taagtgcatc tttttctgta actccaagtg ttcttgataa aattttatct aattcgatta
    20161 ttttttcaac ctcttttttt tcaatctcat ctaccttttg tttattttca attttatcta
    20221 tatagctcca taaaatttta ttattattta aaataagagg tgccttgtat tggaccattt
    20281 aacccatttt gtctcagtat ctcatacgtt aacatattgc ttatattatc tgaaaaactt
    20341 gttatcaatt ttaaccttat atatttggtt ttttcgcttt tagtaatttc tttaagcata
    20401 aacttactat catctataaa ttcattttca cctatattgt ctataactac ttttgtcttt
    20461 aaaataattt ttttaatagg tgccactaaa taaatatata cataatcacc ttttatcaca
    20521 tttttatctg ttccccagtc taattcattt aactctttaa aagctgatat tacattatag
    20581 ctcatactat cgcaagaaaa tacccagttt ttaatatatt tatgtagatg agttttgtta
    20641 ctacaaatat tataaaaagc agataattaa tatctctaat tttattatta atccaaaata
    20701 ttatattgaa aatgaaggtg atactcaaat tataggtaat attgttaccc atgaagtggt
    20761 tgtaggcgag aggactttta aaacctctga ttttgatgat gtattatctt ttagaagagc
    20821 actaaacagc tttaaaactt tttatatagg aagagttgag gaccttcaat atataagatt
    20881 tattatttca aataaaaccc gtgaaataag gaagggtgtt acctacagtg gttttcataa
    20941 aattaataat cagtggtgct tcgtatcgga gcatggcgct ttaaattctg atggaaagcc
    21001 cactttagat atagctatgc aaaatcaata tgcagagctt aatactaata ttc
//
