LOCUS       NZ_CP097721            20900 bp    DNA     circular CON 09-JAN-2024
DEFINITION  Escherichia coli strain MS1665 chromosome, complete genome.
ACCESSION   NZ_CP097721
VERSION     NZ_CP097721.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4724194)
  AUTHORS   Jia,L., Devkota,P., Arick,M.A. II, Hsu,C.-Y., Peterson,D.G.,
            Evans,J.D., Sukumaran,A.T. and Zhang,L.
  TITLE     Complete genome sequence of six multidrug resistance avian
            pathogenic Escherichia coli strains isolated from broilers
            exhibiting colibacillosis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4724194)
  AUTHORS   Jia,L., Devkota,P., Arick,M.A. II, Hsu,C.-Y., Peterson,D.G.,
            Evans,J.D., Sukumaran,A.T. and Zhang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-MAY-2022) Poultry Science, Mississippi State
            University, 46 Old Bully Blvd, 100 Hill Poultry Science Building,
            Mississippi State, MS 39762, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 2.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 438.4x
            Sequencing Technology :: Oxford Nanopore GridION; Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/09/2024 05:20:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,757
            CDSs (total)                      :: 4,638
            Genes (coding)                    :: 4,479
            CDSs (with protein)               :: 4,479
            Genes (RNA)                       :: 119
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 66 of 159
            Pseudo Genes (incomplete)         :: 99 of 159
            Pseudo Genes (internal stop)      :: 48 of 159
            Pseudo Genes (multiple problems)  :: 46 of 159
            Pseudo Genes (short protein)      :: 2 of 159
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:34:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3446266
            Orig. end                         :: 3467166
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP097721.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20900
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20900
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20900
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10900](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10900
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            170..784
                     /gene="cyoC"
                     /locus_tag="M9O79_RS16605"
                     /old_locus_tag="M9O79_16610"
     CDS             170..784
                     /EC_number="7.1.1.-"
                     /GO_function="GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0022904 - respiratory electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /gene="cyoC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414964.1"
                     /locus_tag="M9O79_RS16605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16610"
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="WP_000179819.1"
                     /transl_table=11
                     /translation="MATDTLTHATAHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILFA
                     TYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMYKNNKSQVISWLAL
                     TWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVLMVQ
                     IARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM"
     gene            784..1113
                     /gene="cyoD"
                     /locus_tag="M9O79_RS16610"
                     /old_locus_tag="M9O79_16615"
     CDS             784..1113
                     /EC_number="7.1.1.-"
                     /codon_start=1
                     /gene="cyoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308510.1"
                     /locus_tag="M9O79_RS16610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16615"
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="WP_000019869.1"
                     /transl_table=11
                     /translation="MSHSTDHSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPAV
                     ILGTILAMAVVQVLVHLVCFLHMNTKSDEGWNMTAFVFTVLIIAILVVGSIWIMWNLNY
                     NMMMH"
     gene            1125..2015
                     /gene="cyoE"
                     /locus_tag="M9O79_RS16615"
                     /old_locus_tag="M9O79_16620"
     CDS             1125..2015
                     /EC_number="2.5.1.141"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008495 - protoheme IX farnesyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0048034 - heme O biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyoE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308509.1"
                     /locus_tag="M9O79_RS16615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16620"
                     /product="heme o synthase"
                     /protein_id="WP_000971336.1"
                     /transl_table=11
                     /translation="MMFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLVG
                     VSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLWFG
                     ANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDSGAA
                     ILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAVATLM
                     LSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALSVMMSV
                     DFMVPDSHTLLAAVW"
     gene            2200..2511
                     /locus_tag="M9O79_RS16620"
                     /old_locus_tag="M9O79_16625"
     CDS             2200..2511
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706319.2"
                     /locus_tag="M9O79_RS16620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16625"
                     /product="DUF1778 domain-containing protein"
                     /protein_id="WP_001297137.1"
                     /transl_table=11
                     /translation="MPGKTATLPDVDKTLKNARVELKTSPDAKNKLREAAQAVGVDLSA
                     FILSAAMERAESVLDNQRRRELSNQSWELMNQLIAEPAQPTLALKALMKRKNSDGRQA"
     gene            2495..3037
                     /locus_tag="M9O79_RS16625"
                     /old_locus_tag="M9O79_16630"
     CDS             2495..3037
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227782.1"
                     /locus_tag="M9O79_RS16625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16630"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000227784.1"
                     /transl_table=11
                     /translation="MVDKHEEITLPIVLSCNYQSDITYPGQKQFDCGNPVIDKFVRASL
                     KKSVRNSDCAAKALIDRQSGELIGICTFTAYSLEKQRVSGVLQGSQPSEIGVVRLVMLG
                     VARKYQKRGFGQDLLCDFFEHVKIIHQALPIKGVYLDADPAAINFYARLGFVQLSATPN
                     AFGAVPMFLAIQHILAA"
     gene            complement(3093..4028)
                     /locus_tag="M9O79_RS16630"
                     /old_locus_tag="M9O79_16635"
     CDS             complement(3093..4028)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001427098.1"
                     /locus_tag="M9O79_RS16630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16635"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_001297127.1"
                     /transl_table=11
                     /translation="MLTKRILFSVMLIVSPSVVASEKAHELYDSIYGGKPAPDVINTLH
                     KMAESGDIDAQSLLGWEYYQPRYDTKPDVQEAIKWFELAAKQGDREAPLALGGIYYDGE
                     QVRVDYAKAYALFNQAAQHGVNLAWSRLGIMYANGQYVEVDCKKAKEYLDKGVHIYGGP
                     EDFLATCRKDMIDRKTVDDTLPVITVTRSGMRDNFLDKGFSCMDSLFATTNKLGEVANL
                     RVTFSIRRPSGKEINQTVGFAPFGLNRLNISFTDYLFGSFTSNSSLILYKPEFERKSCA
                     TVRTTIVAATATINGKDVELLKAGAIEQKW"
     misc_feature    complement(4266..4279)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.74"
                     /tool="antismash"
     misc_feature    4274..4288
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.32"
                     /tool="antismash"
     misc_feature    4416..4425
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.59"
                     /tool="antismash"
     gene            4436..5800
                     /gene="yajR"
                     /locus_tag="M9O79_RS16635"
                     /old_locus_tag="M9O79_16640"
     CDS             4436..5800
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yajR"
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308508.2"
                     /locus_tag="M9O79_RS16635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16640"
                     /product="MFS transporter"
                     /protein_id="WP_001000978.1"
                     /transl_table=11
                     /translation="MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQGA
                     SEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIWGI
                     ILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITHKLG
                     LHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLNFGIM
                     CLHMLLMSTFVALPGQLADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRKMKQVF
                     VFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAGYKGTAM
                     GVYSTSQFLGVAIGGSLGGWIDGMFDGQGVFLAGAMLAAVWLAVASTMKEPPYVSSLRI
                     EIPADIAANEALKVRLLETEGVKEVLIAEEEHSAYVKIDSKVTNRFEVEQAIRQA"
     gene            complement(5928..6419)
                     /gene="yajQ"
                     /locus_tag="M9O79_RS16640"
                     /old_locus_tag="M9O79_16645"
     CDS             complement(5928..6419)
                     /codon_start=1
                     /gene="yajQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414960.2"
                     /locus_tag="M9O79_RS16640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16645"
                     /product="nucleotide binding protein YajQ"
                     /protein_id="WP_001138904.1"
                     /transl_table=11
                     /translation="MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDAS
                     KTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGIES
                     ATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKNFRD
                     "
     gene            6587..7498
                     /gene="panE"
                     /locus_tag="M9O79_RS16645"
                     /old_locus_tag="M9O79_16650"
     CDS             6587..7498
                     /EC_number="1.1.1.169"
                     /GO_function="GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414959.1"
                     /locus_tag="M9O79_RS16645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16650"
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="WP_000705874.1"
                     /transl_table=11
                     /translation="MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVETD
                     GSIFNESLTANDPDFLATSDLLLVTLKAWQVYDAVKSLASTLPVTTPILLIHNGMGTIE
                     ELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVLPDV
                     AWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIEREGHHT
                     SAEDLRDYVMQVIDATAENISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVPENTRL
                     FEMVKRKESEYERIGTGLPRPW"
     gene            7461..8051
                     /gene="yajL"
                     /locus_tag="M9O79_RS16650"
                     /old_locus_tag="M9O79_16655"
     CDS             7461..8051
                     /EC_number="3.5.1.124"
                     /codon_start=1
                     /gene="yajL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308505.2"
                     /locus_tag="M9O79_RS16650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16655"
                     /product="protein deglycase YajL"
                     /protein_id="WP_001276309.1"
                     /transl_table=11
                     /translation="MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLAI
                     TCSRGVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIVAA
                     ICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWQDKRVVWDARVKLLTSQGPGTAID
                     FGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     gene            complement(8105..9553)
                     /gene="thiI"
                     /locus_tag="M9O79_RS16655"
                     /old_locus_tag="M9O79_16660"
     CDS             complement(8105..9553)
                     /EC_number="2.8.1.4"
                     /GO_function="GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168857.1"
                     /locus_tag="M9O79_RS16655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16660"
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="WP_000668685.1"
                     /transl_table=11
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVR
                     HWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQLEG
                     KTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPEVTVHLEVEDDRLLLIK
                     GRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQ
                     VAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVAERYGV
                     QALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTM
                     PEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTEQEVVEVE
                     TVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQNRTWLLWCER
                     GVMSRLQALYLREQGFNNVKVYRP"
     misc_feature    complement(9684..9700)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.88"
                     /tool="antismash"
     gene            9759..10001
                     /gene="xseB"
                     /locus_tag="M9O79_RS16660"
                     /old_locus_tag="M9O79_16665"
     CDS             9759..10001
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308503.1"
                     /locus_tag="M9O79_RS16660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16665"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_001124935.1"
                     /transl_table=11
                     /translation="MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQL
                     ARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE"
     gene            10001..10900
                     /gene="ispA"
                     /locus_tag="M9O79_RS16665"
                     /old_locus_tag="M9O79_16670"
     CDS             10001..10900
                     /EC_number="2.5.1.10"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414955.1"
                     /locus_tag="M9O79_RS16665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16670"
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /protein_id="WP_000347217.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1e-66, bitscore:
                     223.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGGK
                     RLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCHVK
                     FGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQALDLD
                     AEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLAFQVQ
                     DDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQLAEQS
                     LDTSALEALADYIIQRNK"
     gene            10925..12787
                     /gene="dxs"
                     /locus_tag="M9O79_RS16670"
                     /old_locus_tag="M9O79_16675"
     CDS             10925..12787
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308501.1"
                     /locus_tag="M9O79_RS16670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16675"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_000006806.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 3.5e-118,
                     bitscore: 391.7, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-05, bitscore:
                     22.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSR
                     SSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGL
                     HPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMAFEA
                     MNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPI
                     KELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIM
                     TKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLM
                     AITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRA
                     YDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECR
                     QMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAILNFGTLMPD
                     AAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAGSGVNEVLMAH
                     RKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA"
     gene            12967..13941
                     /gene="yajO"
                     /locus_tag="M9O79_RS16675"
                     /old_locus_tag="M9O79_16680"
     CDS             12967..13941
                     /EC_number="1.17.1.-"
                     /codon_start=1
                     /gene="yajO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414953.2"
                     /locus_tag="M9O79_RS16675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16680"
                     /product="1-deoxyxylulose-5-phosphate synthase YajO"
                     /protein_id="WP_001199827.1"
                     /transl_table=11
                     /translation="MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIK
                     RALEGGINFFDTANSYSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSRAQ
                     ILRSIDGSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMHASQ
                     FAQALKLQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRP
                     WGETTARLVSDEVGKNLYKESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAA
                     PIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPVVGFK"
     gene            complement(13995..14513)
                     /gene="pgpA"
                     /locus_tag="M9O79_RS16680"
                     /old_locus_tag="M9O79_16685"
     CDS             complement(13995..14513)
                     /GO_function="GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414952.1"
                     /locus_tag="M9O79_RS16680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16685"
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="WP_000154044.1"
                     /transl_table=11
                     /translation="MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLAA
                     IPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITLMA
                     LPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILYFIG
                     HHWPLGILS"
     gene            complement(14491..15468)
                     /gene="thiL"
                     /locus_tag="M9O79_RS16685"
                     /old_locus_tag="M9O79_16690"
     CDS             complement(14491..15468)
                     /EC_number="2.7.4.16"
                     /GO_function="GO:0009030 - thiamine-phosphate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414951.1"
                     /locus_tag="M9O79_RS16685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16690"
                     /product="thiamine-phosphate kinase"
                     /protein_id="WP_000742107.1"
                     /transl_table=11
                     /translation="MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAIS
                     TDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLESFS
                     DSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGTPGD
                     SAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLISDLG
                     HIVKASDCGARIDLALLPFSDALSRHVEPEQALRWALSGGEDYELCFTVPELNRGALDV
                     ALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTFDWKGYDHFATP"
     gene            complement(15546..15965)
                     /gene="nusB"
                     /locus_tag="M9O79_RS16690"
                     /old_locus_tag="M9O79_16695"
     CDS             complement(15546..15965)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308496.1"
                     /locus_tag="M9O79_RS16690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16695"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_000801125.1"
                     /transl_table=11
                     /translation="MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVDV
                     LYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKVAI
                     NEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK"
     gene            complement(15985..16455)
                     /gene="ribE"
                     /locus_tag="M9O79_RS16695"
                     /old_locus_tag="M9O79_16700"
     CDS             complement(15985..16455)
                     /EC_number="2.5.1.78"
                     /GO_component="GO:0009349 - riboflavin synthase complex
                     [Evidence IEA]"
                     /GO_function="GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="ribE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818760.1"
                     /locus_tag="M9O79_RS16695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16700"
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="WP_001021161.1"
                     /transl_table=11
                     /translation="MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVK
                     DENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHV
                     AQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     gene            complement(16544..17647)
                     /gene="ribD"
                     /locus_tag="M9O79_RS16700"
                     /old_locus_tag="M9O79_16705"
     CDS             complement(16544..17647)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="ribD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1240: riboflavin biosynthesis protein RibD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706302.1"
                     /locus_tag="M9O79_RS16700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16705"
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
                     RibD"
                     /protein_id="WP_001150470.1"
                     /transl_table=11
                     /translation="MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQR
                     AGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVASMQDPN
                     PQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGRTAM
                     ASGESQWITSPQARRDVQRQRAQSHAILTSSATVLADDPALTVRWSELDEQTQALYPQQ
                     NLRQPVRIVIDSQNRVTPEHRIVQQPGETWFARTQEDSSEWPETVRTLLIPEHKGHLDL
                     VILMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVYIAPKLLGSDARGLCTLPGLE
                     KLADAPQFKFKEIRHVGPDVCLHLVGA"
     gene            complement(17651..18100)
                     /gene="nrdR"
                     /locus_tag="M9O79_RS16705"
                     /old_locus_tag="M9O79_16710"
     CDS             complement(17651..18100)
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458860.1"
                     /locus_tag="M9O79_RS16705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16710"
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_000543535.1"
                     /transl_table=11
                     /translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAE
                     LVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVP
                     SKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED"
     misc_feature    complement(18109..18124)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.49"
                     /tool="antismash"
     gene            18251..18790
                     /gene="yajI"
                     /locus_tag="M9O79_RS16710"
                     /old_locus_tag="M9O79_16715"
     CDS             18251..18790
                     /codon_start=1
                     /gene="yajI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414946.4"
                     /locus_tag="M9O79_RS16710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16715"
                     /product="DUF3251 domain-containing protein"
                     /protein_id="WP_001297136.1"
                     /transl_table=11
                     /translation="MNTNVFRLLLLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLNK
                     ETVKITQQNRLNAKSSSGVYLLPGAKTPARLESQIGTLRMSLVNITPDADGTTLTLRIQ
                     GESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKGISV
                     DQLGFVRIHDIQPVMQ"
     misc_feature    19040..19055
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.94"
                     /tool="antismash"
     gene            19089..19973
                     /gene="tsx"
                     /locus_tag="M9O79_RS16715"
                     /old_locus_tag="M9O79_16720"
     CDS             19089..19973
                     /codon_start=1
                     /gene="tsx"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308491.1"
                     /locus_tag="M9O79_RS16715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16720"
                     /product="nucleoside-specific channel-forming protein Tsx"
                     /protein_id="WP_001295328.1"
                     /transl_table=11
                     /translation="MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGSY
                     HTRFGPQIRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEIEP
                     RFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMSLSM
                     NVYAKYQWQNYGAANENEWDGYRFKIKYFVPITDLWGGQLSYIGFTNFDWGSDLGDDSG
                     NAINGIKTRTNNSIASSHILALNYDHWHYSVVARYWHDGGQWNDDAELNFGNGNFNVRS
                     TGWGGYLVVGYNF"
     gene            complement(20150..20497)
                     /gene="yajD"
                     /locus_tag="M9O79_RS16720"
                     /old_locus_tag="M9O79_16725"
     CDS             complement(20150..20497)
                     /codon_start=1
                     /gene="yajD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308490.1"
                     /locus_tag="M9O79_RS16720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M9O79_16725"
                     /product="HNH nuclease YajD"
                     /protein_id="WP_000974813.1"
                     /transl_table=11
                     /translation="MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTVH
                     HIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYNPF
                     ADLKAMMNKKK"
ORIGIN
        1 gccatgatct ggcatatctg gtggctggcg attgttggct tcgcaggcat gatcatcacc
       61 tggatcgtga aaagcttcga cgaggacgtg gattactacg tgccggtggc agaaatcgaa
      121 aaactggaaa accagcattt cgatgagatt actaaggcag ggctgaaaaa tggcaactga
      181 tactttgacg cacgcgactg cccacgcgca cgaacacggg caccacgatg caggcggaac
      241 caaaatcttc ggattttgga tctacctgat gagcgactgc attctgttct caatcttgtt
      301 tgctacctat gccgttctgg tgaacggcac cgcaggcggt ccgacaggta aggacatttt
      361 cgaactgccg ttcgttctgg ttgaaacttt cttgctgttg ttcagctcca tcacctacgg
      421 catggcggct atcgccatgt acaaaaacaa caaaagccag gttatctcct ggctggcgtt
      481 gacctggttg tttggtgccg gatttatcgg gatggaaatc tacgaattcc atcacctgat
      541 tgttaacggc atgggtccgg atcgcagcgg cttcctgtca gcgttctttg cgctggtcgg
      601 cacgcacggt ctgcacgtca cttccggtct tatctggatg gcggtgctga tggtacaaat
      661 cgctcgtcgc ggcctgacca gcactaaccg tacccgcatc atgtgcctga gcctgttctg
      721 gcacttcctg gatgtggttt ggatctgtgt gttcactgtt gtttatctga tgggggcgat
      781 gtaatgagtc attctaccga tcacagcggc gcgtcccatg gcagcgtaaa aacctacatg
      841 acaggcttta tcctgtcgat cattctgacg gtgattccgt tctggatggt gatgacaggg
      901 gctgcctctc cggccgtaat tctgggaaca atcctggcaa tggcagtggt acaggttctg
      961 gtgcatctgg tgtgcttcct gcacatgaat accaaatcag atgaaggctg gaacatgacg
     1021 gcgtttgtct tcaccgtgct aatcatcgct atcctggttg taggctccat ctggattatg
     1081 tggaacctca actacaacat gatgatgcac taagagcggc ggttatgatg tttaagcaat
     1141 acctgcaagt aacgaaacca ggcatcatct ttggcaacct gatctcggtg attgggggat
     1201 tcctgctggc ctcaaagggc agcattgatt atcccctgtt tatctacacg ctggttgggg
     1261 tgtcactggt tgtggcgtcg ggttgtgtgt ttaacaacta catcgacagg gatatcgaca
     1321 gaaagatgga aaggacgaag aatcgggtgc tggttaaagg cctgatctct cctgctgtct
     1381 cgctggtgta cgccaccttg ctgggtattg ctggctttat gctgctgtgg tttggcgcga
     1441 atccgctggc ctgctggctg ggggtgatgg gctttgtggt ttatgtcggc gtctatagcc
     1501 tgtacatgaa acgccactca gtctacggca cattgattgg ttcgctctcc ggcgctgcgc
     1561 cgccggtgat tggctactgt gcagtaaccg gcgagttcga tagcggcgca gcgatcctgc
     1621 tggctatctt cagcctgtgg cagatgcctc actcctatgc catcgccatt ttccgcttta
     1681 aggattacca ggcggcaaac attccggtat tgccagtggt aaaaggcatt tcggtggcga
     1741 agaatcacat cacgctgtat atcatcgcct ttgccgttgc cacgctgatg ctctctcttg
     1801 gcggttacgc tggatataaa tatctggtgg tcgccgcggc ggttagcgtc tggtggttag
     1861 gtatggctct gcgcggttat aaagttgctg atgacagaat ctgggcgcgc aagctgttcg
     1921 gcttctctat catcgccatc actgccctct cggtgatgat gtccgttgat tttatggtac
     1981 cggactcgca tacgctgctg gctgctgtgt ggtaacaaaa cctctctatt aaaaaggtgc
     2041 tacggcacct tttttattgt ctgagatcag agatacggct aataaccgta tgtcttgaca
     2101 gagtgagcag atgaacataa attaatcata cggttgatag ccgtattatg tatgagatcg
     2161 actccctacg atttcattca gttaatcaaa gaggtcataa tgcctggaaa aacagccact
     2221 ctacccgatg tcgataaaac gctgaaaaat gcgcgggtcg aactcaaaac cagtcccgac
     2281 gccaaaaaca aacttcgtga agctgcgcaa gccgttgggg tagatttaag cgcttttatt
     2341 ttgagcgctg ctatggaacg cgccgaaagt gtgcttgata accaacgtcg ccgtgagctt
     2401 tcgaatcaaa gctgggaact gatgaaccaa ctcatcgctg aacctgctca accgacgctc
     2461 gccctcaagg cgttaatgaa aaggaaaaac agcgatggtc gacaagcatg aagagattac
     2521 tctgcccata gtcctctcct gtaattatca gtctgatatt acttatcctg ggcaaaaaca
     2581 gtttgattgc ggtaaccctg ttatcgataa atttgtacgc gcatcgctaa agaaaagtgt
     2641 gcgtaatagc gactgtgcgg ctaaagcact tattgacaga caaagtggtg aactgatcgg
     2701 catctgtact tttacggcat attcgctgga aaaacaacgc gtttctggcg tccttcaggg
     2761 ttcacaacct tcagaaattg gtgttgtcag attagtcatg ttgggggtag cacggaagta
     2821 tcaaaagcgg ggctttggtc aggacctact atgtgatttt tttgaacatg taaaaataat
     2881 tcaccaggca ttaccaatta aaggggttta tcttgatgct gaccctgccg ccattaattt
     2941 ttatgctcgt ctcggctttg ttcagctttc agcgacacca aatgcttttg gtgctgtacc
     3001 tatgtttttg gcgattcagc atattctcgc ggcttagatt attatcgcca cccgccaggg
     3061 caagttttgc ctcagccggg ggctgagcag cgttaccact tttgttcaat tgcccccgct
     3121 ttcagcaact ccacatcctt gccgttaatg gttgccgttg cggcaacgat tgtggtcctt
     3181 acagttgcac aagattttcg ctcaaattcc ggtttataaa gaataagaga cgaattactg
     3241 gtaaatgaac caaataggta atcagtaaag ctaatattca gccggtttaa accgaaaggc
     3301 gcgaagccaa ccgtttggtt aatctcctta ccggatgggc gacgaatgct gaatgtcacg
     3361 cgaagattgg ccacttcgcc taatttattg gtggtggcga agaggctatc catgcaggaa
     3421 aaacctttat ctaaaaaatt atctcgcatc ccagaacggg taaccgtaat cacgggtaac
     3481 gtatcgtcaa ccgtttttct gtcaatcatg tcttttcgac aagtagccag aaagtcttcc
     3541 gggccaccat aaatgtggac acctttatca agatattcct tcgctttctt acaatctacc
     3601 tcaacatact gaccattggc gtacataatg cccaacctgg accatgctaa attcacaccg
     3661 tgctgcgcgg cctgattaaa tagtgcatac gctttggcat aatccacccg cacctgctca
     3721 ccgtcgtagt agataccccc cagcgctaac ggagcttctc tgtcaccttg tttagccgct
     3781 aactcgaacc atttaatcgc ttcctgaaca tcaggtttgg tatcataacg aggctgataa
     3841 tattcccagc ctaacaggct ctgcgcgtcg atatctcccg attcagccat tttatgcagt
     3901 gtatttataa catcgggagc aggtttacca ccgtatatgc tgtcatacaa ttcatgcgct
     3961 ttctcgctgg ccaccacgct tggtgaaact atcagcatta cagaaaataa tattctttta
     4021 gttaacatgt atacctttat gtcctcactg tcatatattt ccataataat taaccaccaa
     4081 atatccattt aatgaataaa tacagtgcca taaaggtcca agtaataagc acacatttag
     4141 cctgaaacat tatcatccat gtcaccaaat cgtttattta gtgagataaa actagcatat
     4201 tcgtaagata aaaaatgcac atggcaatca agaaatgata ttattacttt tttgatgtaa
     4261 aactatttag ttttaaaatt cattttttca acatatagag cattcatttt atgaatgcaa
     4321 aaaaacatac ctgacacaca aattactctc ctctgtaata ttttctcatt aacactctgt
     4381 ttacccaaca tgcgctccgc actacactat gtgggcattt ttttaagggg tggtaatgaa
     4441 cgattataaa atgacgccag gtgagaggcg cgcgacctgg ggtttaggga ccgtattctc
     4501 gttgcgcatg ctgggcatgt ttatggttct gccggttctg accacgtacg gcatggctct
     4561 gcaaggtgcc agcgaagcat taatcggtat tgccattggt atttatggtc tgactcaggc
     4621 cgtttttcag attccgtttg gcctgctttc cgaccgcatt ggtcgcaaac cattaattgt
     4681 cggtgggctg gcggtgtttg ccgccggtag cgttatcgct gcgctttccg actccatctg
     4741 gggaattatt ctgggccggg cgctacaagg ctctggagca attgccgccg ccgttatggc
     4801 gctgctttcc gatctcacgc gcgaacaaaa ccgcaccaaa gcgatggcgt ttatcggcgt
     4861 gagctttggc attacctttg ccattgcgat ggtgcttggc ccgatcatca ctcacaaact
     4921 tgggctgcac gcgctgttct ggatgatcgc tattctggca acaaccggca ttgcgttgac
     4981 catttgggtt gtgcccaaca gtagcactca cgtacttaat cgtgagtccg gaatggtgaa
     5041 aggcagtttc agtaaagtgc tggcggaacc gcggctgctg aaactcaact ttggcattat
     5101 gtgtctgcac atgcttctga tgtctacgtt tgttgccctg cccggacagc tagctgatgc
     5161 ggggttcccg gcggctgaac actggaaggt ctatctggcg acgatgttaa tcgcctttgg
     5221 ctcggtcgtg cctttcatta tctacgctga agttaagcgc aaaatgaagc aagtctttgt
     5281 cttctgcgtc gggttgatcg tggttgcgga aattgtgttg tggaacgcac aaacgcagtt
     5341 ctggcaactg gtggtcggcg tgcagctttt ctttgtggcg tttaatttga tggaagccct
     5401 tctgccctca cttatcagta aagagtcgcc agcaggttac aaaggtacgg cgatgggtgt
     5461 ctactccacc agccagtttc ttggcgtggc gattggcggt tcgctgggcg gctggattga
     5521 cggcatgttt gacggtcagg gggtatttct cgctggcgca atgctggccg cagtgtggct
     5581 ggcagtcgcc agtaccatga aagaaccgcc gtatgtcagc agtttgcgca ttgaaatccc
     5641 ggcggacatt gccgcaaacg aagcgttaaa agtgcgtttg ctggaaactg aaggcgtcaa
     5701 agaagtgttg attgcagaag aagagcattc agcttatgtg aaaatcgaca gcaaagtgac
     5761 aaatcgcttt gaggttgaac aggcaattcg tcaggcataa aaaacgcggc gaattgcctg
     5821 ctgcgctacg cttaccaggc ctacaaagtt cttgagttac aaaccgttgt aggccgaatc
     5881 aggcgttcat gccgcatctg acatgaacaa aacgcacatt gtcgcgatta atcgcggaag
     5941 tttttgaact ggaacggctg gccgagatcg ccaccacgta ccatcgccat gacagcctgc
     6001 aaatcatcac gagatttgcc agtcacacgg atctcatcgc cctgaatttg cgcctgcact
     6061 ttcagtttgc tgtctttaat catcttgacg attttcttct gggtcgcgct ctcaatgccc
     6121 tgtttcagtt tcgcttccac aaaccaggtt ttaccgctat gaacgatatt ttccggtaca
     6181 tccagtgaac tgccttcaat gccgcgcttc agcagcttgg cacgcagaat atccagcaac
     6241 tgattgacct ggaagtcgga ctcgctcaac actttgatgg ttttgctggc gtcgttcagc
     6301 tcaaatgagg cttcaacgtt acggaagtca aaacgggact ccacttcgcg actcgcgtta
     6361 tcgaccgcgt tacgtgcttc ctgaagatca acttcagaga caatatcgaa agatggcatc
     6421 ttttcctctc ccttcatttt tgatgcgaag cataatacct gcaaagttaa ataaccaaca
     6481 gtcctgcacc aggacgtatc ccttaattgt gcatagtcgc aacagcatgc acaattaagg
     6541 gatagcctta ttgaacaccc ggagtggttg cgggtgagga ggaacaatga aaattaccgt
     6601 attgggatgc ggtgccttag ggcaattatg gcttacagca ctttgtaaac agggtcacga
     6661 agttcagggc tggctgcgcg taccgcaacc ttattgtagt gtgaatctgg ttgagactga
     6721 tggttcgata tttaacgaat cgctgaccgc caacgatccc gattttcttg ccaccagcga
     6781 tctgctcctg gtgacgctga aagcatggca ggtttacgat gccgtcaaaa gcctcgcgtc
     6841 cacactgcct gtaaccacgc caatactgtt aattcacaac ggcatgggca ccatcgaaga
     6901 gttgcaaaac attcagcagc cattactgat gggcaccacc acccatgccg cccgccgcga
     6961 cggcaatgtc attattcatg tggcaaacgg aatcacgcat attggtccgg cacggcaaca
     7021 ggatggcgat tacagttatc tggcggatat tttgcaaacc gtgttgcctg acgttgcctg
     7081 gcataacaat attcgcgccg agctgtggcg caagctggcc gtcaactgtg tgattaatcc
     7141 actgaccgcc atctggaatt gcccgaatgg tgaattacgt catcatccgc aagaaattat
     7201 gcagatatgc gaagaagtcg cggcagtgat cgagcgcgaa gggcatcata cttcagcaga
     7261 agatttgcgt gattacgtga tgcaggtgat tgatgccaca gcggaaaata tctcgtcgat
     7321 gttgcaggat atccgcgcgc tgcgccacac cgaaatcgac tatatcaatg gttttctctt
     7381 acgccgcgcc cgcgcgcatg ggattgccgt accggaaaac acccgcctgt ttgaaatggt
     7441 aaaaagaaag gagagtgaat atgagcgcat cggcactggt ttgcctcgcc cctggtagtg
     7501 aagagactga agccgtcacc actatcgatc tgctggttcg cggcggtatc aaagtcacca
     7561 ctgccagcgt cgccagcgat ggcaacctgg ccattacctg ctcgcgcggc gtgaagctgc
     7621 tggcggatgc gccgctggtc gaggtggctg atggcgaata tgacgtgatc gtactgcctg
     7681 gtggcattaa aggcgcagag tgttttcgcg atagtaccct gctggttgaa accgttaaac
     7741 agttccaccg ttccgggcgt atcgtcgcgg ctatttgcgc cgcgccagcc accgtgctgg
     7801 tgccgcacga tatcttcccg attggtaata tgaccggctt cccgacgctg aaagacaaaa
     7861 ttcccgctga acaatggcag gacaagcgcg tcgtctggga tgcacgggta aaattgctga
     7921 ccagccaggg gccggggaca gctatcgact ttggtctgaa aattatcgac ctgctggttg
     7981 ggcgcgagaa agcccatgaa gtggcatcac aactggtgat ggcggcaggg atttataatt
     8041 attacgagta gtgtcggatg cggtaagcgt cgcatctgac cagatgcgac gttacaacca
     8101 caaattacgg gcgatatacc ttcacattgt taaagccctg ctcgcgcaga tagagcgcct
     8161 gcagacggct catcaccccg cgctcacacc acagtagcca ggttctgttc tggtcgagat
     8221 cgccaaactt ggtgctcagt ttatagaacg gcagagaaac tacatcaatc ccttcgactt
     8281 tcagtggctt atcttcctgt tcatcgatag aacggatatc gaggatcacg tcgttcgggc
     8341 cgaagccatt gacggtttcc acttccacca cttcctgctc ggtctgctgg gcgatttcgc
     8401 ggatatcaac gttattcgct tcttcaacca ctttatcgag aatgctgaag tcgaatttct
     8461 cttcttccgc ttcaatcttc gacttaaccg ctttcaccgt cgggcttttg gagataacac
     8521 cgcaatattc cggcatcgtg cgagcaaagt cttcggtgcc aatctggcga gccaggttga
     8581 tgatgtgctc tttgtcgtaa gaaatcagcg gacgcaggat cagcgtatcg gagacgttat
     8641 caatcaggcg caggttggtc agcgtctgac tggacacctg gccgagcgct tcgccggtga
     8701 ccagcgcctg tacgccgtaa cgttcagcca ctttagacgc ggcacgcacc atcatacgtt
     8761 tgaggataac gcccatctga ccgtcgtcga ttttctcgag aatttccccg acgaccggtt
     8821 cgaaattaat agcgacaaaa cgcacgcggt gggagctgcc aaaacggttc cacagataat
     8881 gcgccacctg acgcacgcca atttcatgcg ccgcgccgcc aaggttaaag aaacagtaat
     8941 gcacgcggca gccgcgacgc atcaacatat aactggaaac accggagtcg aaaccaccgg
     9001 aaatgagcga cagcacatct tcctgggtgc cgatcgggaa accgccaata ccttcgtagc
     9061 ggcctttaat cagcaggaga cgatcgtctt ccacttccag atggacagtc acttccggat
     9121 tggtcagctt cacgcgcgcg gactcaatat gctgatttaa accgccgccg acgtaacgtt
     9181 ccacatcaat cgagctaaaa tcatgtttgc cacggcgctt cacgcgtacg cagaaggttt
     9241 tgccttccag ctgatcgcga tactgaacca acgctttctc aaaaatatcg tgcatgtcgg
     9301 taaacggcac gtcttcgact tcgagaatat ggtggatacc cggaatacgg gtcagggcgt
     9361 cgcgaatagc cagacgctgg ttttcatctt ttgcgcgaac ttcgatgtta tcccagtggc
     9421 ggacgacagc gagcgtctca tcatagtgct ttaaaacgtt acgaatgttc ccggtaagga
     9481 tttttataaa gcgcaagcgc acagattggc ttttgatggt gatttccggg aacaatttaa
     9541 tgataaactt catggcggca atggttcgtt ggcaagcctt aagcgacttg tatagggaaa
     9601 aatacagcag cccacacctg cggctgcatc caggcgcgga agtataccac taacatcgct
     9661 ttgctgcgca catcacctta ccattgcgcg ttatttgcta tttgccctga gtccgttacc
     9721 atgacggggc gaaaaatatt gagagtcaga cattcattat gccgaagaaa aatgaggctc
     9781 ccgccagctt tgaaaaggcg ctgagcgagc tggaacagat tgtaacccgt ctggaaagtg
     9841 gcgacctgcc gctggaagag gcgctgaacg agttcgaacg cggcgtgcag ctggcacgtc
     9901 aggggcaggc caaattacaa caagccgaac agcgcgtaca aattctgctg tctgacaatg
     9961 aagacgcctc tctaacccct tttacaccgg acaatgagta atggactttc cgcagcaact
    10021 cgaagcctgc gttaagcagg ccaaccaggc gctgagccgt tttatcgccc cactgccctt
    10081 tcagaacact cccgtggtcg aaaccatgca gtatggcgca ttattaggtg gtaagcgcct
    10141 gcgacctttt ctggtttatg ccaccggtca tatgttcggc gttagcacaa acacgctgga
    10201 cgcacccgct gccgccgtag agtgtatcca cgcttactca ttaattcatg atgatttacc
    10261 ggcgatggat gatgacgatc tgcgtcgcgg tttgccgacc tgccatgtga agtttggcga
    10321 agcaaacgcg attctcgctg gcgacgcttt acaaacgctg gcgttctcga ttctaagcga
    10381 tgctgatatg ccggaagtgt cggatcgcga cagaatttcg atgatttctg aactggcgag
    10441 cgccagcggt attgccggaa tgtgcggtgg tcaggcatta gatttagacg cggaaggcaa
    10501 acacgtacct ctggacgcgc ttgagcgtat tcatcgtcat aaaaccggcg cattgattcg
    10561 cgccgccgtt cgccttggtg cattaagcgc cggagataaa gggcgtcgtg ctctgccagt
    10621 actcgacaag tacgcagaga gcatcggcct tgccttccag gttcaggatg acatcctgga
    10681 tgtggtagga gatactgcaa cgttgggaaa acgccagggt gccgaccagc aacttggtaa
    10741 aagtacctac cctgcacttc tgggtcttga gcaagcccgg aagaaagccc gggatctgat
    10801 cgacgatgcc cgccagtcgc tgaaacaact ggctgaacaa tcactcgata cctcggcact
    10861 ggaagcgcta gcggactaca tcatccagcg taataaataa acaataagta ttaataggcc
    10921 cctgatgagt tttgatattg ccaaataccc gaccctggca ctggtcgact ccacccagga
    10981 gttacgactg ttgccgaaag agagtttacc gaaactctgc gacgaactgc gccgctattt
    11041 actcgacagc gtgagccgtt ccagcgggca cttcgcctcc gggctgggca cggtcgaact
    11101 gaccgtggcg ctgcactatg tctacaacac cccgtttgac caattgattt gggatgtggg
    11161 gcatcaggct tatccgcata aaattttgac cggacgccgc gacaaaatcg gcaccatccg
    11221 tcagaaaggc ggcctgcacc cgttcccgtg gcgcggcgaa agcgaatatg acgtattaag
    11281 cgtcgggcat tcatcaacct ccatcagtgc cggaattggt attgcggttg ctgccgagaa
    11341 agaaggcaaa aatcgccgca ccgtctgtgt cattggcgat ggcgcgatta ccgctggcat
    11401 ggcgtttgaa gcgatgaatc acgcgggcga tatccgtcct gatatgctgg tggtcctcaa
    11461 cgacaatgaa atgtcgattt ccgaaaatgt cggcgcgctc aataaccatc tggcacagct
    11521 gctttccggt aagctttact cttcgctgcg cgaaggcggg aaaaaagttt tctctggcgt
    11581 tccgcccatt aaagagctgc tcaaacgtac cgaagaacat attaaaggca tggtagtgcc
    11641 tggcacgttg tttgaagagc tgggctttaa ctacatcggc ccggttgacg gtcacgatgt
    11701 gctggggctt atcaccacgc tgaagaacat gcgcgacctg aaaggcccgc agttcctgca
    11761 tatcatgacc aaaaaaggtc gtggttatga accggcagaa aaagacccca tcactttcca
    11821 cgccgtgcct aaatttgatc cctccagcgg ttgtttgccg aaaagtagcg gcggtttgcc
    11881 gagctattca aaaatctttg gcgactggtt gtgcgaaacg gcagcgaaag acaacaagct
    11941 gatggcgatt actccggcga tgcgtgaagg ttccggcatg gtcgagtttt cacgtaaatt
    12001 cccggatcgt tacttcgacg tggcaatcgc cgagcaacac gcggtgacct ttgccgccgg
    12061 tctggcgatt ggtgggtaca aacccattgt cgcgatttac tccactttcc tgcaacgcgc
    12121 ctatgatcag gtgctgcatg acgtggcgat tcaaaagctc ccggtcctgt tcgccatcga
    12181 ccgcgcgggc attgttggtg ctgacggtca aacccatcag ggcgcttttg acctctctta
    12241 cctgcgctgt ataccggaaa tggtcattat gaccccgagc gatgaaaacg aatgtcgcca
    12301 gatgctctat accggctatc actataacga cggcccgtcc gcggtgcgct acccgcgcgg
    12361 taacgcggtt ggcgtggaac tgacgccgct ggaaaaactg ccaattggca aaggcattgt
    12421 gaagcgtcgt ggcgagaaac tggcgatcct taactttggt acgctgatgc cagacgcggc
    12481 gaaagtcgct gaatcgctga acgctacgct ggtcgatatg cgttttgtga aaccgcttga
    12541 tgaagcgtta attctggaaa tggccgccag ccatgaagcg ctggtcaccg tagaagaaaa
    12601 cgccattatg ggcggcgcag gcagcggcgt gaacgaagtg ctaatggccc atcgtaaacc
    12661 agtacccgtg ctgaacattg gcctgcctga cttctttatt ccacaaggaa ctcaggaaga
    12721 aatgcgcgcc gaactcggcc tcgatgccgc cggtatggaa gccaaaatca aggcctggct
    12781 ggcataatcc ctactccact cctgctatgc ttaacaaatt attcatagac tctaaataat
    12841 tcgagttgca ggaaggcggc aaacgagtga agccccagga gcttacataa gtaagtgact
    12901 ggggtgaacg aatgcagccg cagcacatgc aacttgaagt atgacgagta tggcaggagt
    12961 ggcagcatgc aatacaaccc cttaggaaaa accgaccttc gcgtttcccg actttgcctc
    13021 ggctgtatga cctttggcga gccagatcgt ggtaatcacg catggacact gccggaagag
    13081 agtagccgtc ccatcattaa acgcgcgctg gaaggcggca taaatttctt tgataccgcc
    13141 aatagctatt ccgatggcag cagcgaagag atcgttggtc gcgcactgcg ggatttcgcc
    13201 cgtcgtgaag acgtggtcgt tgccaccaaa gtgttccatc gcgttggtga tttaccggaa
    13261 ggattatccc gtgcacaaat tttgcgctct atcgacggca gcctgcgacg tctcggcatg
    13321 gattatgtcg atatcctgca aattcatcgc tgggattaca acacgccgat cgaagagacg
    13381 ctggaagctc tgaacgacgt ggtaaaagcc gggaaagcgc gttatatcgg cgcgtcatcc
    13441 atgcacgctt cgcagtttgc tcaggccctg aagctacaaa aacagcacgg ctgggcgcag
    13501 tttgtcagta tgcaggatca ctacaatctg atttatcgcg aagaagagcg cgagatgctg
    13561 ccactgtgtt atcaggaggg cgtggcggtg attccgtgga gcccgctggc gcgggggcga
    13621 ctgacgcgtc cgtggggaga aactaccgca cgactggtgt ctgatgaggt ggggaaaaat
    13681 ctctataaag aaagcgatga aaatgacgcg cagatcgcag agcggttaac gggcgtcagt
    13741 gaagaactcg gtgcaacacg agcacaagtt gcgctggcct ggttgttgag taaaccgggc
    13801 attgccgcac cgattatcgg tacatcgcgg gaagaacagc ttgatgagct attgaacgcg
    13861 gtggatatca ctttgaagcc ggaacagatt gccgaactgg aaacgccgta taaaccgcat
    13921 ccggtagtag gatttaaata agagtccagg cctgatgaga cgcaacaagc gtcacatcag
    13981 gcatcggtgc acaactacga cagaatgccc agcggccagt gatgaccaat aaagtacagg
    14041 atgccagcgg agatcacccc ggcgacaata tcatctatca tgatccccat gccgccatgc
    14101 acattgcgat caaaccagcg gatcggccac ggtttccaca tatccagaat acggaaaatc
    14161 acaaacccgg cggcaaccca ctgccagtca ttggtcggca gcgccatgag cgtgatccac
    14221 ataccaataa attcgtccca gacaatgctg ccgtgatcgt gcacgcccat atcttttgcg
    14281 gtctgatgac aaagatagac gccgatacag atccccagca tcaccaccag cgagtagagc
    14341 tgccagggca aaaaggtcat cagataccag aacggaatcg ctgccagcga gcccatcgtc
    14401 ccaggaacga tcgggcttaa tccacttccg aatccgacag caagcagatg ccacggatta
    14461 ctcatcttca ggcgactttt cgcgacatct ttatggcgtg gcaaaatggt catatccttt
    14521 ccagtcaaac gtgacaggtt cgccgtcacg aataaaacaa agcccttcga tatcggcggt
    14581 catttgcccg atacaggtaa acggtacgcc aaggtgtccg agagcaacat ccagcgcgcc
    14641 acggttcagt tccggcaccg tgaaacacaa ctcgtaatct tcaccgccag agagcgccca
    14701 gcgcagcgcc tgttccggtt caacatggcg agaaagcgca tcagaaaacg gcagcaatgc
    14761 caggtcaata cgtgcgccgc agtcgctggc tttcacgata tgcccgagat cggaaatcag
    14821 accgtcagag agatcgatag ctgaatttgc cagatcgcgc agtgcctgcc cctgtaaaat
    14881 acgcggcgat ggacggagat gacgtttgat caagtagtca gcatctttag catcggcaac
    14941 ctgcaaacgg ttttgcaaaa tcgccagccc ggcggcgcta tcgcccggtg taccggtcac
    15001 atagatccag tcacccggtt tcgccccaga gcgcgttaag gctcgtccca tcggaacaaa
    15061 gccgtggata cccaacgtca ttgataatgg cccacgcgtg gtatcgccgc caatgagttg
    15121 catatcgtaa taattgagaa gatcaaacaa actgtcgctg aaggactcaa gccacgcttc
    15181 gtctacgtcc ggtaaggtta atgccagcgt cagccaggcc ggatcggccc ccatcgctgc
    15241 cagatcgctt aggttcaccg ccagtgcttt ataagccaga tcagcaggat cgatatcagg
    15301 gaggaaatgg ttacccgcca ccagcgtatc agtgctgatc gccagggtct gtttctcggg
    15361 gatattgaga agtgcgcaat cgtcgccgat gcccagttcg acatcaagac gagaacttct
    15421 tacacggtca aaataacggg caatcaggga gaactcgcca catgccatac gttatgcctc
    15481 agcaggtaaa aaagaaaagg ccggcgatca tggaacggtc ttccgtgaat ctaccggcct
    15541 ggatatcact ttttgttagg gcgaatcaca ggtgctgctt tatcgagtac gccgttgacg
    15601 aacttatggc tgtcttctgc gccgaacgat ttcgccagtt cgatcgcttc gttaatggcc
    15661 actttgtatg gcacatcgct acgtttagac agttcgtaca gcgcaatgcg cagtactgct
    15721 ttttctacct gtcccagttc ttccagcagg cgggacaggt atggcttcat cagtccgtcg
    15781 aggtatgcgg tattagtcgc caccccggcc agcagctcac ggaagtacag gacgtcaacg
    15841 tcttttacat cctgttcagc caggaactgg tattcaacat cagcgatgtc gttctgggac
    15901 aactgccagg agtagagcgc ctggacggca cactcacgag cgcggcgacg agcagcaggt
    15961 ttcacggatt tccccttact aatttcaggc cttgatggct ttcaatacat taatcatttc
    16021 aagcgcggtc agtgcagctt ctgcaccttt gttgccagct ttggtgccag cacgttcgat
    16081 cgcttgttca atgctttcag tggtcagaac cccaaaagca accggaattt cgctgtcctg
    16141 ggcaacatgc gccaggccgt tgcttgcacc accagcgaca tattcaaagt gggcagtgcc
    16201 accacgaata accgtaccca gcgcaatcac cgcgtcgtat ttaccggttt tagccagtgc
    16261 acccgccgcc agcggcagct cataggcacc aggcacccaa acaacggtaa tgttttcatc
    16321 ttttacctga ccgatacgtt tcagtgcgtc aattgcacct tccagcaggc tgtcattgat
    16381 aaagttgttg aaacgcgcga tggtgatggc gacgcgagcg tccggggtag caacgttagc
    16441 ttcaataatg ttcattttct tccttcgggt tcgagtatgg ccccgcaggg gggcggattt
    16501 tagcataata tttcgtgcgc tgcttccctt tcgagccggg agatcatgca cccactaaat
    16561 gcaggcaaac atccgggcct acatgacgta tctctttgaa tttaaattgg ggggcgtcgg
    16621 ctaatttctc aagccctggc agcgtgcata atccgcgggc gtcgctgcct aatagtttag
    16681 gtgcgatata gacaatcagc tcatcgacta aacccgcctg cagcaatgcg ccagcgagcg
    16741 ttggccccgc ttccacccag atgctgttaa tttgctgttt acccagttgc atcatcagta
    16801 taaccagatc cagatgacct ttatgctctg gaatcagcaa ggtacgcacc gtttccggcc
    16861 actcactaga atcttcctgc gtacgcgcga accaggtttc gccgggctgc tgcacaatgc
    16921 gatgttccgg cgtcacgcga ttttggctat caatcacaat acgtactggc tggcggagat
    16981 tttgttgcgg gtagagcgcc tgagtttgtt catccagttc agaccaacgc actgttaagg
    17041 ctggatcatc cgccagcacc gtggcgctgc tggttaaaat ggcatgactt tgtgcgcgct
    17101 gtcgttgtac gtcgcgccgc gcctgaggcg aagtgatcca ctggctttcg ccgctcgcca
    17161 tcgccgtgcg gccatcaagc gatgcgccaa gttttaactg aatataagga aagccggtgc
    17221 gcatccgctt gagaaagcct ttattcaatt gctcggcttc actcatcatc agcccgtggc
    17281 tgacgtcaat gccagcctgt tgcagacggt aaagtccacg cccagcgacc tgcgggttag
    17341 gatcttgcat cgaggcaacc acgcgcgcta cgccagcggc gatgagtgcg tcacagcacg
    17401 gtggcgtacg accatgatgg ctacagggtt cgagtgtgac ataggcggtc gcacctttgg
    17461 ctttttcacc cgccatacgc aacgcgtgta cttcggcatg tggttcaccc gcacgttggt
    17521 ggtaaccttc accgacaatt tcgccatctt tgacaatgac gcacccgaca ttcgggttgg
    17581 gatgcgtggt aaaacgtcct cgttgcgcca gctttagcgc ccgcgccatg taatactcgt
    17641 cctgcacggc ttagtcctcc aggcgcgcga tctcttcgcc aaattctttg atatcttcga
    17701 aactgcggta gacagaggca aaacggatat aggcgacttt atcgagcttt ttcaattgct
    17761 ccatcaccag attgccaatc atcttgctcg gcacttcgcg ctcaccggtg gcgcgcagct
    17821 gcgatttaat atgattgatt gccatttcga cgtcatcgga actcaccgga cgtttttcca
    17881 gcgcccgcag cattccgcta cgcaatttct cttcattaaa cggttcacgc acgtcgttgc
    17941 tttttacaac acgcggcata accagctccg ccacttcaaa ggtggtgaaa cgttcattac
    18001 acaccagaca ctgccgacgg cggcgtacgg atgaaccctc gcccacgaga cgagagtcaa
    18061 ttaccttagt gtccacggcg aaacagaatg ggcaatgcat acggcgtcct gaccaggtgg
    18121 ttaacagaaa tctattttac cctgaactga cgatacaaca aaggcgcaac gcttttgaga
    18181 taaaggatcg atgctttcgc tgcttttacc ctctaccatt aggctaattg cgacgagaaa
    18241 gggacgacct atgaatacta acgtttttcg actgctcctg ctgggaagcc tgttcagcct
    18301 tagcgcctgt gtgcagcaga gcgaagtgcg acagatgaaa cacagcgtca gcacgctgaa
    18361 ccaggagatg acgcaactca ataaagaaac ggtcaaaatc actcagcaaa acaggctgaa
    18421 tgcaaaatcc agcagtgggg tttaccttct gcctggagcg aaaacaccgg caagactgga
    18481 aagccagatc ggtactttac gtatgtcgct ggtgaatatt acgcctgatg cagatggcac
    18541 caccctgacg ctacgtattc agggcgagtc gaatgatccc ttgcccgcat tcagcggaac
    18601 tgttgaatat gggcaaattc agggaacaat agacaacttt caggaaatca atgtgcagaa
    18661 tcaattgatt aatgcccctg ccagcgtcct cgcccccagc gatgttgata ttccgttaca
    18721 attaaagggg atttctgtgg atcagttagg ctttgtacgt atccacgaca ttcaacctgt
    18781 tatgcagtaa acgtatttcg ggacgatttt gtgcgtcccg caacatattt ccccgtcatt
    18841 ttgttactct gcttacatca cctggattga tagtaaaagt ttgcaacaag ggcgaaagtc
    18901 agtacaatcc ccgcccgaat gtgtgtaaac gtgaacgcaa tcgattacgt aaatgataga
    18961 actgtgaaac gaaacatatt tttgtgagca atgattttta taataggctc ctctgtatac
    19021 gaaatattta gaaacgcaat ttgcgccttt ttcactcccg caagggattt tcaaacagtg
    19081 gcatacatat gaaaaaaaca ttactggcag ccggtgcggt actggcgctc tcttcgtctt
    19141 ttactgtcaa cgcagctgaa aacgacaaac cgcagtatct ttccgactgg tggcaccaga
    19201 gcgttaacgt tgtcggaagc tatcacaccc gttttggacc gcagatccgc aacgatacct
    19261 accttgagta cgaagcattc gctaaaaaag actggttcga cttctatggt tatgcggatg
    19321 cgccggtatt cttcggcggt aactccgatg ccaaaggtat ctggaaccac ggctctccgc
    19381 tgtttatgga aatcgaacca cgtttctcca tcgacaagct gaccaatact gaccttagct
    19441 tcggtccgtt caaagagtgg tacttcgcga acaactacat ttacgacatg ggtcgtaata
    19501 aagatggtcg ccagagcacc tggtatatgg gtctgggtac cgacatcgat actggtctgc
    19561 cgatgagcct gtccatgaac gtctatgcga aataccagtg gcagaactat ggcgcagcga
    19621 acgaaaacga gtgggacggt taccgtttca aaattaaata ctttgtgccg attaccgatc
    19681 tgtggggcgg tcagctgagc tacatcggct tcaccaactt cgactggggt tccgatttag
    19741 gggatgacag cggtaacgca atcaacggta ttaagacccg tactaataac tctatcgctt
    19801 ccagccatat tctggctctg aactacgatc actggcacta ctctgtcgta gctcgttact
    19861 ggcacgacgg tggtcagtgg aacgacgatg cagaactgaa cttcggcaac ggcaacttca
    19921 acgttcgctc taccggctgg ggtggttacc tggttgtagg ttacaacttc tgattatgaa
    19981 aatgccggga tttattcccg gcatttcaga ttgttaacaa cgtgcgcttt gttcatgccg
    20041 gatgcggcgt aaacgctttg tccgacccac aaaagcacgt aaattcaata tattgctgaa
    20101 ataacgtagt cctgataagc gtagcgcatc aggcaatttt acgttttaat cacttcttct
    20161 tgttcatcat cgctttcagg tcagcgaatg ggttgtactt cgcttcaccg acatctttct
    20221 gcgcatcttc ccctgcgata acggtcgtac catactgatc cgcttcggta tatttcgaat
    20281 gctcatgatc gtggcaatag agacaaagca attcccagtt actgccatct tccgggttat
    20341 tggtatggtc gtgatcaatg tggtgaacag taagttcacg caggttggaa tagacaaact
    20401 cgcgggaaca gcgaccgcag acccacggat agatttttaa tgctttttcg cgatagccgc
    20461 tttctaaccg cgcatagttt tttgggatga tagccatgaa aagttacctg gatgaaatgt
    20521 agggttacgc gcagtttccc aagatgcggg gattttcgca atctccatac atcaaaaaaa
    20581 atcccgatct tctgaccggg attttcaaca tcaacgggaa cttgattaag gcagaattga
    20641 cggctgatcc gccccttctt tttccacttt ctgctgcaac atgtgttcgc gcttcatacc
    20701 cagtttcaga gccaacgcag atgccacata gatggaagat gcagtaccga tggaaacacc
    20761 gataagcatg gtcagcgaga agccttccag taccggacca ccgaagaggt acagcatcag
    20821 gataaccatc aaggtagtac cggatgtgat caaggtacgg tgcagcgtct gggtcaagga
    20881 cacgttaaag atttcgtaag
//
