LOCUS       NZ_CP102665            20792 bp    DNA     circular CON 07-JAN-2024
DEFINITION  Sphingobium sp. JS3065 chromosome 2, complete sequence.
ACCESSION   NZ_CP102665
VERSION     NZ_CP102665.1
KEYWORDS    RefSeq.
SOURCE      Sphingobium sp. JS3065
  ORGANISM  Sphingobium sp. JS3065
            Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
            Sphingomonadaceae; Sphingobium.
REFERENCE   1  (bases 1 to 1017992)
  AUTHORS   Li,T., Xu,J., Xu,Z.-J., Xu,Y., Spain,J.C. and Zhou,N.-Y.
  TITLE     Molecular mechanism and evolution of 1-nitronaphthalene catabolism
            in Sphingobium sp. strain JS3065
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1017992)
  AUTHORS   Li,T., Xu,J., Xu,Z.-J., Xu,Y., Spain,J.C. and Zhou,N.-Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2022) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 800 Dong-Chuan Road, Shanghai,
            Shanghai 200240, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. v0.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio RS
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/07/2024 05:42:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,942
            CDSs (total)                      :: 4,873
            Genes (coding)                    :: 4,751
            CDSs (with protein)               :: 4,751
            Genes (RNA)                       :: 69
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 122
            CDSs (without protein)            :: 122
            Pseudo Genes (ambiguous residues) :: 0 of 122
            Pseudo Genes (frameshifted)       :: 40 of 122
            Pseudo Genes (incomplete)         :: 96 of 122
            Pseudo Genes (internal stop)      :: 12 of 122
            Pseudo Genes (multiple problems)  :: 23 of 122
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:10:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 478034
            Orig. end                         :: 498826
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102665.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20792
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="3"
                     /rules="Autoind_synth"
                     /tool="antismash"
     cand_cluster    1..20792
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20792
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10792](+)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10792
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     gene            274..663
                     /locus_tag="NUH86_RS19530"
                     /old_locus_tag="NUH86_19535"
     CDS             274..663
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013054090.1"
                     /locus_tag="NUH86_RS19530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19535"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_267252970.1"
                     /transl_table=11
                     /translation="MTTSPDLAIRLRRADFNRALAEADLNAIAPLLALHAVLVTGSDSA
                     VISGRKAQLQAWKREFGASERIVYSRTPESIVASTVEPIAMEHGRWQGVAAGSDQPLAS
                     GSYSAKWRRVGVDWIIEAEIYLTLA"
     gene            760..2796
                     /locus_tag="NUH86_RS19535"
                     /old_locus_tag="NUH86_19540"
     CDS             760..2796
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007686402.1"
                     /locus_tag="NUH86_RS19535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19540"
                     /product="M3 family metallopeptidase"
                     /protein_id="WP_267253008.1"
                     /transl_table=11
                     /translation="MTTANPLLADHDLPDFAAIQPAHVVPAMEEAIAAHRAAVESITAS
                     GKDDFDAVILAAERADFLLSRVWSPVGHLASVADTPELREAHAAAQALMTAYLMEAGQN
                     RAHHDAVARLAARPDFAALPAAARRAVDLALRGFHLAGVALEGEARQRFLDIGVGLSDL
                     STKFGNAVLDATEAWSEHITDEAALAGVSESDKAILAAYAQEKGLPGWLITLRQPSVLA
                     ILYHAQDRALRERVYRAYNSRASDQADDKSHDNSERIDAIMALRHEAAQILGFADSAAH
                     SLETKMAADADEALAFLADLARRARPVGEGELAEARAFAAEHLGLDDVQPWDLSYVAEA
                     MRRTLHGVDQEALKAYFPLPRVLAGTQALIERLFDVRLAAREGVSTWHPDVLFYDVLDA
                     GGAVVAGVYLDLFARAGKRGGAWMDVCRSRFRDADRLHLPIAYLTTNFAPPAGDRPSLA
                     THNDVVTLFHEFGHVLHHLLTEVDLPSIGGISGVEWDAVELPSQFMENFAWDRDTLIGL
                     SGHVESGEPLPEAMFDRLLAARQFQAGLAILRQIEFATFDLLLHRDYDPAKGARVDAVL
                     DQVRKAVAVIQPPAWNRFAHAFSHIFAGGYAAGYYSYLWAELLSADAFEIFAHGDIAGG
                     GATAFRREILAAGASRPAAENFRAFAGRGPEVDALLRMRGLAA"
     misc_feature    797..813
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.15"
                     /tool="antismash"
     gene            complement(3221..4510)
                     /locus_tag="NUH86_RS19540"
                     /old_locus_tag="NUH86_19545"
     CDS             complement(3221..4510)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1137: Major
                     facilitator superfamily MFS 1"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010336057.1"
                     /locus_tag="NUH86_RS19540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19545"
                     /product="MFS transporter"
                     /protein_id="WP_267252971.1"
                     /transl_table=11
                     /translation="MLSATLARHMGARHIHYGWAVLAATFLTMLVVAGAVGAPGVFIAP
                     LQKEYGWSAADISGALAIRFLLFGGMGPFAAAFMNRFGVRRMMLISLSIIVGGLLLSTG
                     MTELWQLVLLWGVVIGIGTGLTAMVLGATVATRWFSHRRGLVVGLLSASTATGQLAFLP
                     LLAGLTERFGWRASVLLMCGAILLAAMVVLLLMRDRPSDVGLPPYGDREVHPTPPQPAG
                     FGALLMTPLRILADAARVPSFWILFFSFYICGASTNGLVQTHFIPLCGDYGLAAVGAAS
                     MLAMMGLFDFVGTLASGWLSDRFDNRWLLFWYYGLRGLSLLYLPFSDFSLYSLSVFAIF
                     YGLDWVATVPPTVKLTAQRFGPERANVVFGWIFAGHQLGAASAALAGGLSRTIWQSYMP
                     AFVAAGILCLIGAGMVLLINRGRSKAFALA"
     gene            complement(4644..6758)
                     /locus_tag="NUH86_RS19545"
                     /old_locus_tag="NUH86_19550"
     CDS             complement(4644..6758)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013849353.1"
                     /locus_tag="NUH86_RS19545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19550"
                     /product="EAL domain-containing protein"
                     /protein_id="WP_267252972.1"
                     /transl_table=11
                     /translation="MDDDQQFLASAGVSRCSVDGEGLCWPDPVARHFGLRDAQPLVRWL
                     RGVRPIFRKPVFQLIRAALREGGGEATLTLEDGDGALKNMRVAARTRRDAAGRLTGDMV
                     MVDLTGEQAEIGRLRRSMENLRLIVEYNPQLPWIADPDGRIIDFTDRWLENSGLEREEA
                     EGNGWLATTHPDDIGPLTQRIGHSLTSGEPFDVRVRLMVNDQYRWMRAQAYPRRDEDGH
                     IIRWYGYTEDIHESVLIEEQIRWNAEHDSLTELPNRAMFNACLDKALADAMTSFRKVGV
                     FLLDIDNFKDVNDLMGHHAGDELLKSFAARLKEIFADDAVVARLGGDEFAILIQDVENR
                     QQLAALANRILTIRETFFAAGRSLECRVSIGVASFPDDGRVATELLRHADLALYRAKSL
                     GRGRMQMFEPSLLEDMQERVAMINRARTAVRDGTIISYYQPKVSLQTGELVGFEALLRW
                     RDSCGTIRSPAEIYAAFDDHDVADMIGQTMTSQVFADMAAWRARGLPVGHVAINVSSAE
                     LRRERFAGRLIETMDRFSIQPDAIEIEITEGVFLGAGSDTVRRSIDELHRCHIPLALDD
                     FGTGFASLSHLRSLPVSTLKIDRSFVSGVTARESDAAIVSALITLGRALNMKVVAEGVE
                     EADQSIKLKEMGCDYAQGFYFGRPTPSENIPALIHSWNENSAVVSLNRRPASWPLRGTR
                     GEGRPDWLTA"
     misc_feature    6842..6860
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.38"
                     /tool="antismash"
     gene            complement(6925..9063)
                     /locus_tag="NUH86_RS19550"
                     /old_locus_tag="NUH86_19555"
     CDS             complement(6925..9063)
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1107:
                     TonB-dependent receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821232.1"
                     /locus_tag="NUH86_RS19550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19555"
                     /product="TonB-dependent receptor"
                     /protein_id="WP_267252973.1"
                     /transl_table=11
                     /translation="MAGLASGGTAWAEVRDDGDSRADITVTARKVPESLLKAPLAVTSI
                     SGDTIVAAGLQTLTDLTRMAPNVDISGGIAGQLQGQISIRGISTLVRNIGLETGVGIYV
                     DGVYIGRPENFVQHLLDVDRVEIARGPQGTEYGKNTIAGVVNVQTKQPDADPGASFRLD
                     AGNYDYRRAEGVLGMRLNDRVSVRGAVAYARQDGFYKHLSGGKDAGSTDLLTWRLSAKY
                     APTDQLSFIARWEGLRDRGTPAFFQADALAGYPADFPSREPLHVNNNRPNRLHRDSQGV
                     SLTAEWTSDAVTLTSITAYRDSSYNAALDDDQEQVDFVAADNFSDDSHFFSQELRLSGG
                     AGKLRYLLGVYYFDQMVRTDRGIALGANTGVPGEPMLTTKGSVKTESGALFGRLDYELT
                     DRLSLSAGLRYTRERKRAHFVQDDASGTGIFTFLGFPNLTFDGRSTDDDLSPSATISYA
                     VAPDANVYARFSRGFKSAAYNVDLASSLGGLDASPEKATSYEIGFKALTLDKRLRLNLA
                     VFHTDYDRLQVSQVLGSGLALTNAGRARVEGVEGELSLQLSSRLRLEGNAAVLDAHYKR
                     FDNCGVPASLIPPGGSNRTDCTGNDLVLAPHFTGYGAVNYEVPVSFGTIFARADVDHRS
                     TVYFEPTNSDAFKSDPRTLVNLRLGLRHGQWDIAAWVQNLTDKVYKTYADDRSGLGVFR
                     TAAYGAPRTYGVSLSAAF"
     misc_feature    complement(9090..9101)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    9157..9173
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.62"
                     /tool="antismash"
     gene            9333..9881
                     /locus_tag="NUH86_RS19555"
                     /old_locus_tag="NUH86_19560"
     CDS             9333..9881
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821234.1"
                     /locus_tag="NUH86_RS19555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19560"
                     /product="hypothetical protein"
                     /protein_id="WP_267252974.1"
                     /transl_table=11
                     /translation="MSEYIPSTQLRAGSSTTAADFIAGVDATLTIDKLVTRFSQALGLQ
                     AASHACYAVEGDSRRFLFGETGWSGPVAQPEILPRLCFSIIGWDEKHYEVEIRLLSMLE
                     SREERANLHAMATLYLCRGIALLDARDDATAPSLTETELFCLDRRREGWCDLDIADALE
                     RSVQAVKVHIQRAQGKQRA"
     gene            10001..10792
                     /locus_tag="NUH86_RS19560"
                     /old_locus_tag="NUH86_19565"
     CDS             10001..10792
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821235.1"
                     /locus_tag="NUH86_RS19560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19565"
                     /product="acyl-homoserine-lactone synthase"
                     /protein_id="WP_267252975.1"
                     /sec_met_domain="Autoind_synth (E-value: 1.9e-25, bitscore:
                     85.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHLISKNNSALYQDEIRDLHQARAEVFVNQLGWDLRVSDGLEYD
                     EYDDARASNIIGFSTENRVVMGLRFRPTDDCSMLLDHFSHVLPAGIRPIDDGRTWELSR
                     GFCVERGMRRHNLRRKAACMIAPLELALEAGIDRCVGFTDVRMLSFCYGVGWKLTLLGS
                     AMDYGQGEAVAYEVEVSQAALDEMRQMWGLPRPSHVTVDDLLPGEESAHVAAARMARDN
                     PELQKIAAQPEIGSSAQPSAAGRTDVYYSGFGTTRQAAGGH"
     gene            10792..11100
                     /locus_tag="NUH86_RS19565"
                     /old_locus_tag="NUH86_19570"
     CDS             10792..11100
                     /NRPS_PKS="Domain: PP-binding (16-82). E-value: 1.6e-12.
                     Score: 39.6. Matches aSDomain:
                     nrpspksdomains_NUH86_RS19565_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013849349.1"
                     /locus_tag="NUH86_RS19565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19570"
                     /product="acyl carrier protein"
                     /protein_id="WP_267252976.1"
                     /sec_met_domain="PP-binding (E-value: 1.5e-10, bitscore:
                     37.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSDSIRQAPAEEIESWIVARIAEMVNVAPAAISADAPFDSFGID
                     SAKAISLMVELENWLNLPDELPLELLFEAEAIRDAAAGIAEAVADMAAAQAEGSAAR"
     aSDomain        10840..11037
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NUH86_RS19565_PP-binding.1"
                     /evalue="1.60E-12"
                     /label="NUH86_RS19565_PP-binding.1"
                     /locus_tag="NUH86_RS19565"
                     /protein_end="82"
                     /protein_start="16"
                     /score="39.6"
                     /tool="antismash"
                     /translation="WIVARIAEMVNVAPAAISADAPFDSFGIDSAKAISLMVELENWLN
                     LPDELPLELLFEAEAIRDAAA"
     gene            11097..11963
                     /locus_tag="NUH86_RS19570"
                     /old_locus_tag="NUH86_19575"
     CDS             11097..11963
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013054099.1"
                     /locus_tag="NUH86_RS19570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19575"
                     /product="cyclopropane-fatty-acyl-phospholipid synthase
                     family protein"
                     /protein_id="WP_267252977.1"
                     /transl_table=11
                     /translation="MMQDELIEYGGSAAAIRHHYDVGNDFYSAWLDPTMTYSSAMWDGL
                     PKDAPLEEAQRRKLAYHAESVGAAEGMRILDVGCGWGGMMRNLRNSYGVAECVGLTLSE
                     EQLAYIEQLGDPGIGAVLSNWHDYRPDRPFDAIISVGAFEHFAHPQQSVDERRGVYREF
                     FQACRDWTAGKGRLSLQTIAYGKMSPEDANPFISNEIFPAAELPTLEDIVIASKGLFRI
                     ERLRDDGLDYARTCEMWSNKLRGAVRSGVVDPAVHPVEKYSRYLRMSAAGFRMRKIGLL
                     RIAFAAE"
     gene            11988..13748
                     /locus_tag="NUH86_RS19575"
                     /old_locus_tag="NUH86_19580"
     CDS             11988..13748
                     /NRPS_PKS="Domain: CAL_domain (38-464). E-value: 4e-106.
                     Score: 347.1. Matches aSDomain:
                     nrpspksdomains_NUH86_RS19575_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013849347.1"
                     /locus_tag="NUH86_RS19575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19580"
                     /product="fatty acyl-AMP ligase"
                     /protein_id="WP_267252978.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 2.5e-186, bitscore:
                     617.2, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-87, bitscore:
                     290.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIDFSRSIIDIVLDHENGVPDRPALIFDVGEGPQDSLTYAQVAA
                     RVRQLAGALSARGLAGRQIALLFSAGTDFALALLACLAVGGIAVPLAPVGRRRARLQNI
                     LNMLGDIRPDCVMLDDSMAGQFGQELSATLPGAVSYLEFSGLAGESHPFTPLRLEADRL
                     AVLQYTSGTTSNPKGVMITHGNIIANETMIKAAFCHSQDSHFVGWVPHYHDQGLFGNIL
                     QPLFLGSTCVITSPAAFINKPMSWLQLITRYRAHTSGGPNFGYDLCVDHATRRGMPELD
                     LSSWRVAFNGAERVRPSTMDRFAECFADAGFDRRAFLPCYGLAESTLVTIAVPPQSEPM
                     VRTYDSRALAAGRAEESAEGIDLACCGPAMAGGEARIVDPGTGEPLPDGAVGEIWLRGP
                     HIAAGYLNNAAATEETFGGRLDEGGPFLRTGDLGFSTADGFFIVSRLKDVIIVRGRNYA
                     PSDVEHIWSEISGTVEQASAAAVEMEVDGVQHIALIAELKRDEARNLSVETLRETAGKL
                     RAIAMERLELGITDLVMVPASAIPRTTSGKVQRKQAARLLMEGELAVLGMTGPLEHNFK
                     PLRQKATAGG"
     misc_feature    12008..12023
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.7"
                     /tool="antismash"
     aSDomain        12102..13379
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NUH86_RS19575_CAL_domain.1"
                     /evalue="4.00E-106"
                     /label="NUH86_RS19575_CAL_domain.1"
                     /locus_tag="NUH86_RS19575"
                     /protein_end="464"
                     /protein_start="38"
                     /score="347.1"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="TYAQVAARVRQLAGALSARGLAGRQIALLFSAGTDFALALLACLA
                     VGGIAVPLAPVGRRRARLQNILNMLGDIRPDCVMLDDSMAGQFGQELSATLPGAVSYLE
                     FSGLAGESHPFTPLRLEADRLAVLQYTSGTTSNPKGVMITHGNIIANETMIKAAFCHSQ
                     DSHFVGWVPHYHDQGLFGNILQPLFLGSTCVITSPAAFINKPMSWLQLITRYRAHTSGG
                     PNFGYDLCVDHATRRGMPELDLSSWRVAFNGAERVRPSTMDRFAECFADAGFDRRAFLP
                     CYGLAESTLVTIAVPPQSEPMVRTYDSRALAAGRAEESAEGIDLACCGPAMAGGEARIV
                     DPGTGEPLPDGAVGEIWLRGPHIAAGYLNNAAATEETFGGRLDEGGPFLRTGDLGFSTA
                     DGFFIVSRLKDVIIVRGRNYAPSDVEH"
     CDS_motif       12477..12536
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NUH86_RS19575_0001"
                     /evalue="8.80E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="NUH86_RS19575"
                     /protein_end="183"
                     /protein_start="163"
                     /score="24.5"
                     /tool="antismash"
                     /translation="AVLQYTSGTTSNPKGVMITH"
     CDS_motif       13146..13235
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NUH86_RS19575_0002"
                     /evalue="1.70E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="NUH86_RS19575"
                     /protein_end="416"
                     /protein_start="386"
                     /score="36.3"
                     /tool="antismash"
                     /translation="PDGAVGEIWLRGPHIAAGYLNNAAATEETF"
     gene            13880..14461
                     /locus_tag="NUH86_RS19580"
                     /old_locus_tag="NUH86_19585"
     CDS             13880..14461
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013849346.1"
                     /locus_tag="NUH86_RS19580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19585"
                     /product="hypothetical protein"
                     /protein_id="WP_267252979.1"
                     /transl_table=11
                     /translation="MRWTPAISLLLAATAGPAFAQQMILPEGMAIQLETRQALSSKSAR
                     VGDAVELAVAKPVTIGGVTLIPAGSPATGTVSRVRDNGLLGRSGKLDIKVSAIKLGGID
                     VPVRGQRNAQGKSGTLGAVGAGIVFLPLAVIIRGKDVKLPAGTPFEVYVDREVSIGPAV
                     PAAPAAVSSDSPAATSVIRTIDPNQAIGAE"
     gene            complement(14471..15373)
                     /locus_tag="NUH86_RS19585"
                     /old_locus_tag="NUH86_19590"
     CDS             complement(14471..15373)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017500250.1"
                     /locus_tag="NUH86_RS19585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19590"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_267252980.1"
                     /transl_table=11
                     /translation="MSINRIGLFHLETLLWIDRLGTFAAAAERLNTTQPAISARVRELE
                     GHLGARLFRREGRTMSFTAAGRQLVRDCGPLWSDLQSMLLRCGGLEEATGVVRVGAGEI
                     AAASCLPAFVAQLKADMPHVSLELEIDLTANLIQQLLVGRTDIAFAAGPLAHPSLQSSP
                     IGAVRLAWLASPAVAASFHGDALDRTIPIWSLASHSPIYGRMRDAIAASRIAHQSLNLC
                     NNARMMIDIAKAGGGIGIFPEPMARDDLTSGALVELEGMPPLAPIDFHVAKRISDTDPV
                     IHAIFVRASALRLGPDGAA"
     misc_feature    15368..15382
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.27"
                     /tool="antismash"
     misc_feature    complement(15369..15384)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.0"
                     /tool="antismash"
     misc_feature    complement(15388..15397)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.35"
                     /tool="antismash"
     gene            15458..16168
                     /locus_tag="NUH86_RS19590"
                     /old_locus_tag="NUH86_19595"
     CDS             15458..16168
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010335662.1"
                     /locus_tag="NUH86_RS19590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19595"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_267252981.1"
                     /transl_table=11
                     /translation="MVKKLYSDAASALEGLLFDGMHLCAGGFGLCGIPERLIDAIRDSG
                     VRDLTIASNNAGIDGEGLGKLLRTRQVKKMISSYVGENKEFERQYLAGELEVEFCPQGT
                     LAERCRAGGAGIPGFYTKTGVGTAVAEGKEVKNFDGQDYILERGIFADVAIIKGWKADE
                     SGNLIFRKTARNFNQPMATAAKICVAEVEEVVPTGSLDPDAIHLPGIYVKRMIVGAPYD
                     KKIEFRTVRQRETA"
     gene            16168..16848
                     /locus_tag="NUH86_RS19595"
                     /old_locus_tag="NUH86_19600"
     CDS             16168..16848
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013849343.1"
                     /locus_tag="NUH86_RS19595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19600"
                     /product="CoA transferase subunit B"
                     /protein_id="WP_267253009.1"
                     /transl_table=11
                     /translation="MAQETKGQETKGQKTKGWSRDEMAARAAKELQDGFYVNLGIGIPT
                     LVANHIPAGVEVTLQSENGMLGIGPFPYEGEEDADLINAGKQTISELPQSVYFSSADSF
                     AMIRGGHIDLTVLGAMEVSENGDIANWMIPGKMIKGMGGAMDLVAGVKKIIVVMEHTSK
                     DGSPKFIPACTLPLTGRNVVDMIITDLAVFQRPDHDSPFKLIECAPGVTAEEIAARTSA
                     HYTV"
     gene            16990..17775
                     /locus_tag="NUH86_RS19600"
                     /old_locus_tag="NUH86_19605"
     CDS             16990..17775
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1295: Sel1 domain
                     protein repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF019843.4"
                     /locus_tag="NUH86_RS19600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19605"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_267252982.1"
                     /transl_table=11
                     /translation="MWRRSREWGLERRRARALAAAPFPCPRWALFCCLLLFPFPCPAGP
                     FEDAAAAYRRGDYANAMRLYQSLADGGDPRAQNSLGRMYLRGQGAGRDYRQAMKWFRRA
                     AALGVADAQFHLGEIYLREFGVEQDLVEAARWYTRAAEQGHIGAQFTLAVLYTIGRGVS
                     RSPLKAVYWFERAASQGNAAAQVQLGIIYGAGQGVARDSVAAYKWFALGQANARESKLR
                     AKASQNMNRLSRGMTPAQIAEAQRQAREWQPVPARGGQS"
     gene            17772..20573
                     /locus_tag="NUH86_RS19605"
                     /old_locus_tag="NUH86_19610"
     CDS             17772..20573
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015859.4"
                     /locus_tag="NUH86_RS19605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19610"
                     /product="response regulator"
                     /protein_id="WP_267252983.1"
                     /transl_table=11
                     /translation="MNKPPPLSPAPPLSTANGPRNWLKGGVKYGFALIVGIVSLLLTLG
                     VWQWLVLGQSRSTETEFSLEAEQRAEGIKRQFFSETSVIRALLGYYQASQDVSPEEFKA
                     FAKVYLTGLSSLDSVQWAPYVPGGERRDWEEKGAAFRFTQVDAHGAAVGADRRGSYFPI
                     VYAESATGGAPETLGFDWGSDPFARGAMLAARDSGEINAAAHIRLPRMDDGTPRIALFA
                     PVYDGGEQIAVDQRRKHLKGFVVAVLRIGDVIQGAIDLMPRKGVDLYLLDSSAPAAQRV
                     LLSIMAPGSKAKRRPGAGPAMDSDLFHSSSLVIGNSVFTIYTAATDAYGDKRGATTPTI
                     ALAGGLAVTLILFIYLVSLANQRARTEQVVAQRTAELRGVNMRLEERTIQLEESETELR
                     AAKNRAEEATRAKSQFLANMSHEIRTPMNGVIGAAELLNDTRLNASQREYLTMITQSAD
                     ALLHLINDILDFSKIEAGRLELEHVAFSLRDELADTLQAFAGRATEKGIELACHVALDV
                     PDALEGDPHRLRQVIINLVGNALRFTERGEVVMDVAIQWMEQPQIRLRFAVSDTGPGIA
                     ADKRQLIFEAFSQADTSFTRRFGGTGLGLTIASQLVQLMGGRLELDSAVGRGSVFHFTI
                     PFALAQGEPARLPAEQPSLHGLPVLIVDDNATNRRILEEMIRGWGMKPLAVESGPKALA
                     ALRNAAGIGRPLRLVLLDMMMPDMDGFAVAKEMARSGEAQRPAVIMLSSARKDEVARRN
                     WATGIAAFLLKPVRQSELLEAIFAVLKVTVREETALPEPVPDDRPSLHVLVAEDNAVNQ
                     RLALRLLEKRGHRVKIVGDGAQAVEALAQDRFDVVLMDVQMPEMDGFQATAAIRERERG
                     QGKHMPIIAMTAHAMRGDRERCLAAGMDDYISKPLRAEDFYEVVEGRFASAAKPHSEEG
                     SRP"
ORIGIN
        1 cgtccgctcg aacaggatca cgttgggatc gcggaggaat tcctggcggg cggcggcgcg
       61 gaagcggtgc caatgaatga ttaggagagg taacagagac attttcgtcc ttccgggatc
      121 gatttcctat ttatctattt tatcggtaga gataagtctc acaagcaatg ctgaacccac
      181 tattagaaat gcttgaccga tgctgagggt cgatcatgcg ctgaaacaag ttcagcatga
      241 cggtttgagg aaatggctct agctattcgg tccatgacga catcccccga ccttgccatt
      301 cgcctgcgcc gcgccgattt caaccgtgcc ctggcggagg cggacctgaa cgccatcgcg
      361 ccgctgctgg cgctccacgc cgttctcgtc accggatcgg acagcgccgt catttcgggg
      421 cggaaggcgc agctccaggc atggaagcgg gaattcggcg cgagcgagcg catcgtctat
      481 agccggacgc cggaaagcat cgtcgcgtcc acggtggaac ccatcgcgat ggaacacgga
      541 cgatggcagg gcgtggccgc cgggtcggac cagcccctcg catcgggaag ctatagcgcc
      601 aaatggcggc gggtaggcgt ggattggatc atcgaggcgg aaatctatct gacgctcgcc
      661 tgatttgcgc gttggtcgga aatgcttgaa cagccgcccg tcagcgccca attagaagct
      721 gttcctttcc catttcagac ctgcgaattg cgagtgatga tgacgaccgc caaccccctt
      781 cttgccgatc acgacctgcc cgatttcgcg gcgattcaac ccgcgcacgt cgtccccgcg
      841 atggaagagg cgatcgccgc ccatcgcgcc gccgtcgaaa gcatcaccgc cagcggaaag
      901 gacgatttcg acgcggtcat cctggccgcc gaacgggccg atttcctgct gtcgcgggtc
      961 tggtcgccgg tggggcatct cgcctccgtg gccgacacgc ccgaattgcg ggaggcgcat
     1021 gccgccgccc aggcgctgat gaccgcctat ctgatggagg cggggcaaaa ccgcgcccat
     1081 catgacgccg tggcccggct ggccgcccgt cccgatttcg ctgccctgcc cgctgccgcc
     1141 agacgcgccg tcgatctggc gctgcgtggt ttccatctgg cgggcgtcgc gctggagggc
     1201 gaggcgcggc agcgcttcct ggacatcggc gtgggcttga gcgacctcag caccaaattc
     1261 ggcaatgccg tgctcgacgc gacggaggcg tggagcgaac atatcaccga cgaagcggcg
     1321 ctggccgggg tttcggaaag cgacaaggcg atcctggcgg cctatgcgca ggaaaagggc
     1381 ctgcccggct ggctgatcac gctgcgccag ccgagcgtgc tggcgatcct ctatcatgcg
     1441 caggaccgcg cgctgcggga gcgtgtctat cgcgcctaca acagccgcgc ctccgatcag
     1501 gctgacgaca agagccacga caatagcgag cggatcgacg cgatcatggc gttgcggcat
     1561 gaggccgcgc agatattggg ctttgccgat tccgccgctc attcgctgga gaccaagatg
     1621 gccgccgacg ccgatgaggc gctggccttc ctggccgacc tcgcccgccg ggcgcggccg
     1681 gtgggggaag gcgagctggc ggaggcccgc gccttcgcgg ccgagcatct ggggctggac
     1741 gatgtgcagc cgtgggatct ttcctatgtg gccgaagcga tgcgccgcac cctgcacggc
     1801 gtggatcagg aggcgttgaa ggcctatttc cccctgcccc gcgtgctggc ggggacgcag
     1861 gcgctgatcg aacggctgtt cgacgtccgc ctggccgctc gcgaaggcgt gtcgacatgg
     1921 catccggacg tgctgttcta cgacgtgctg gatgcgggcg gcgcggtggt ggcgggcgtc
     1981 tatctcgacc tgttcgcgcg ggcgggcaaa aggggcggcg cgtggatgga cgtttgtcgg
     2041 tcccgcttcc gcgacgccga tcggctgcat ctgcccatcg cctatctcac caccaatttc
     2101 gcgccgcccg cgggcgaccg gccttcgctg gcaacgcata atgacgtggt gacgctgttc
     2161 cacgaattcg gccatgtgct gcatcacctg ctgacggagg tcgacctgcc gtccatcggg
     2221 ggcatcagcg gggtggaatg ggatgcggtg gaactgccca gccagttcat ggagaatttc
     2281 gcctgggatc gggacacgct gatcgggctg tccggccatg tcgagagcgg ggagccgttg
     2341 ccggaggcga tgttcgaccg gctgctggcg gcgcgtcagt tccaggcggg cctcgccata
     2401 ttgcgccaga tcgagttcgc gaccttcgat ttgctgttgc atcgggacta tgatccggcg
     2461 aagggcgcgc gggtcgatgc ggtgctggat caggtgcgca aggcggtcgc cgtgattcaa
     2521 ccgcccgcct ggaaccgctt tgcccatgcg ttcagccata ttttcgcggg cggctatgcg
     2581 gcgggctatt attcctattt gtgggcggaa ctgctgtcgg ccgatgcgtt cgagattttc
     2641 gcccatggcg acatagcggg cggcggcgcg accgctttcc ggcgcgagat cctcgcggcg
     2701 ggggcgagcc gccccgccgc cgagaatttc cgcgcctttg ccgggcgcgg cccggaggtc
     2761 gacgccttgt tgcgaatgcg gggactggct gcctagagcg atttccagtc agatggcatc
     2821 atctgacgtt taagaaatcg cggtaaaaca acggaataga gcgcatctgc ggcatgcgat
     2881 attgtgcctg caggtagagg atcattatgt ccgggtgcac ggcgtcgacg gcagcgcgat
     2941 ggtgctgatc cggttcagcg acgcgatacg cggaatgacc caccttgccg ggtcgcaggt
     3001 gcatcgtagc tggtgggtgg ccaatgacgc ggtccgaacg ctgcgccgca cgagccgtac
     3061 cgcgcagctc accctttcga acgaaatgat cgtgccggta tcccagccct atgtcgccga
     3121 cgcggtgagc cgctgggggc gcgctgcaat ccgccatctg aaatgcgaac tcagccgtca
     3181 gtcttctttc cctggggcat ccattcttct cctcatccgg tcaggcgagg gcgaaggcct
     3241 tgctccgccc gcgattgatc agcagcacca ttcccgcccc gatcaggcac aatatccccg
     3301 ccgcgacgaa ggcgggcata tagctttgcc agatcgtgcg ggaaaggccg cccgccagcg
     3361 ccgcgctggc cgcgccgagc tgatgcccgg cgaagatcca gccgaacacg acattggccc
     3421 gttccggccc gaagcgctgc gccgtcagct tgaccgtcgg cggcacggtg gccacccagt
     3481 ccaggccata gaatatcgcg aacaccgaca ggctgtagag cgagaaatcg ctgaacggca
     3541 ggtagagcag cgacagcccg cgcagcccat aataccagaa tagcagccag cgattgtcga
     3601 accggtccga cagccagccg gaagccagcg tgcccacgaa atcgaacagg cccatcatcg
     3661 ccagcatcga cgccgcgccc accgccgcca gcccataatc gccgcaaagc gggatgaaat
     3721 gggtctggac cagcccgttg gtgctggcgc cgcagatgta gaaggagaag aacaatatcc
     3781 agaagctggg cacccgcgcc gcatcggcca atatgcggag cggcgtcatc agcagcgcgc
     3841 cgaaaccggc gggctgcggc ggggtgggat gcacttccct gtcgccatat ggcggcaggc
     3901 cgacatcgga cgggcggtcg cgcatcagca gcagcacgac catggccgcc agcaggatcg
     3961 cgccgcacat cagcaggacc gaggcgcgcc agccgaaacg ctccgtcagg ccggcgagca
     4021 gcggcaggaa ggccagttgg cccgtggcgg tgctggccga cagcagaccc accaccaggc
     4081 cgcgccggtg cgaaaaccag cgggtggcga cggtggcgcc cagcaccatg gcggtcaggc
     4141 ccgtgccgat gccgatgacg acgccccaga gcagcacgag ttgccacagt tccgtcatgc
     4201 ccgtggacag cagcaggccg ccgacgatga tcgacagcga gatcagcatc atccgccgca
     4261 cgccgaaccg gttcatgaag gcggccgcga acggccccat cccgccgaag agcaggaaac
     4321 ggatggccag cgcccccgaa atatccgccg cgctccagcc atattccttt tgcaggggtg
     4381 cgatgaacac gcccggcgcg cccacggccc ccgcgacgac tagcatagtc aggaaagtgg
     4441 cggccagcac cgcccagcca taatgaatat gccgcgcgcc catatggcga gcgagggtcg
     4501 ctgacaacat gaaggcccct gtcccggacg attgccgggc gttagatgat gttcgtcatg
     4561 acaaggtcaa ggggccagtt ggcgcaatct ggatatgaag ggccgtcggc gatccggtca
     4621 ggcgccgatg tccccgcccc ctttcaggcg gtcagccagt ccggtcgacc ttcgcctcgc
     4681 gttccgcgca agggccatga tgccgggcgg cggttgaggg agacgacggc gctgttctcg
     4741 ttccagctat ggatcagcgc cggaatattc tccgaagggg tgggcctgcc gaagtaaaat
     4801 ccctgggcat aatcgcagcc catttccttg agcttgatcg actggtccgc ttcctcgacg
     4861 ccttcggcca cgaccttcat gttgagcgcg cgtcccagcg tgatcagcgc ggacacgatg
     4921 gcggcgtcgc tttcccgcgc cgtcacgccg ctgacgaagg agcggtcgat cttcagcgtg
     4981 ctgaccggca gggaccgcag gtgggacagg gacgcgaagc cggtcccgaa atcgtccagc
     5041 gccaggggga tgtggcagcg gtgcagttcg tcgatggacc ggcggacggt gtccgatccc
     5101 gcgcccagga agacgccttc ggtaatctct atctcgatcg cgtccggctg tatggagaag
     5161 cggtccatcg tctcgatcag gcgtccggcg aaccgttccc gtcgcagttc ggccgaagac
     5221 acgttaatcg cgacatgccc cacgggcagg ccgcgcgcgc gccaggcggc catgtcggcg
     5281 aacacctggc tggtcatggt ctggccgatc atgtccgcca cgtcatgatc gtcgaacgcc
     5341 gcatagattt cggcgggcga gcggatcgtg ccgcaactgt cgcgccagcg cagcagcgcc
     5401 tcgaacccga ccagttcgcc ggtctgcaac gacactttgg gctgataata gctgatgatc
     5461 gtgccgtcgc gcacggcggt cctggcccgg ttgatcatgg ccacccgctc ctgcatgtcc
     5521 tccagcaggg acggttcgaa catctgcatg cgcccgcggc ccagcgactt ggcgcgatag
     5581 agcgccaggt ccgcatggcg cagcagctcc gtcgcgacgc gaccgtcgtc ggggaaggag
     5641 gcgacgccga tgctgacccg gcattcgagc gaccggcccg ccgcgaaaaa ggtttcgcgg
     5701 atggtgagga tgcggttggc cagggccgca agctgctgcc ggttttcgac atcctggatc
     5761 aatatggcga attcgtcgcc gcccaggcgt gccaccaccg cgtcgtcggc aaagatttcc
     5821 ttcaggcgcg cggcgaagct cttcaacagt tcgtcgccgg catgatggcc catcaggtca
     5881 ttgacgtcct tgaaattgtc gatgtccagc aggaacaccc cgaccttcct gaagctggtc
     5941 atcgcgtcgg ccagcgcctt gtccaggcag gcgttgaaca tcgcccggtt gggcagttcc
     6001 gtcagcgaat catgctcggc gttccagcgt atctgctctt cgatcagcac gctttcgtgg
     6061 atatcctcgg tatagccgta ccagcggatg atatggccgt cctcgtcccg ccggggatag
     6121 gcctgcgccc gcatccagcg atattggtcg ttgaccatca gccggacgcg cacgtcgaag
     6181 ggttcgccgc tggtcagcga atggccgatg cgctgggtca gcggcccgat atcgtccgga
     6241 tgcgtcgtcg caagccagcc attgccctcc gcctcctccc tttccagacc ggaattttcc
     6301 agccagcggt cggtgaagtc gatgatccgg ccgtccggat cggcgatcca gggaagctgc
     6361 ggattatatt cgacgatcag gcgcagattt tccatgctgc ggcgcagccg gccgatttcc
     6421 gcctgctcgc ccgtcaggtc gaccatcacc atgtcgccgg tcagccgtcc cgccgcatcg
     6481 cgccgggtcc gcgcggcgac gcgcatgttc ttcagcgcgc cgtcgccgtc ttccagggtc
     6541 agcgtcgctt cgcccccgcc ctcgcgcagt gcggcgcgga tgagttggaa caccggtttg
     6601 cggaagatcg gacggacgcc gcgaagccag cggaccaggg gctgcgcatc gcgcagcccg
     6661 aaatggcggg cgaccgggtc gggccagcac agcccctccc cgtcgaccga gcagcgcgaa
     6721 acgcccgccg acgccagaaa ctgctggtcg tcatccatcg ggccctgcct gccttgcaat
     6781 tcgtcaggtg accgcgatga aatctggtcc gtcattctac tcctgccaac ccccgacggg
     6841 ccttgcgaat gtttcaccat ctgccggcta agatttgatt aatggccgca tccgcgacac
     6901 gggcagatcc ttgggagcgc ggcattaaaa tgctgccgac aggctgactc cataggtgcg
     6961 gggcgccccg taggccgccg tcctgaacac ccccagcccc gaccggtcgt cggcataggt
     7021 cttgtagacc ttgtcggtca gattctggac ccaggcggcg atgtcccatt gcccgtgccg
     7081 caggccgagg cgaagattca ccagcgtgcg cggatcggat ttgaaggcgt cggaattggt
     7141 cggctcgaaa tagacggtcg aacgatgatc cacgtccgcc cgggcgaaga tggtgccgaa
     7201 gctcacggga acttcataat tgaccgcgcc atagccggtg aagtggggcg ccaacaccag
     7261 gtcgttgccg gtgcagtccg tgcggttgct tccgcctgga ggaatgagcg atgcggggac
     7321 gccgcaattg tcgaacctct tataatgcgc gtcgaggacg gcggcattcc cctccagccg
     7381 caggcgggac gatagttgca gcgacaattc gccctccaca ccctccaccc gcgcacggcc
     7441 cgcgttggtc agcgccagcc cgctgcccag cacctgcgac acctgcagcc ggtcgtaatc
     7501 ggtatggaag accgccaggt tcagccgcag ccgcttgtcc agcgtcagcg ccttgaaacc
     7561 gatttcgtag ctggtcgcct tttccgggct ggcgtccagg ccgccgagcg aggaggcgag
     7621 gtcgacatta taggccgcgc tcttgaaacc gcgggagaag cgcgcataga cgttggcgtc
     7681 cggcgcgacc gcataggaaa tggtcgcgct cggcgacagg tcgtcgtcgg tcgagcggcc
     7741 gtcgaaggtc aggttgggga agcccaggaa ggtgaaaatg cccgtgccgc tggcgtcgtc
     7801 ctgcacgaaa tgggcgcgct tcctctcgcg ggtgtagcgc aggcccgcgg agagcgagag
     7861 gcgatcggtc agttcatagt cgagccgccc gaacaacgcg ccgctctccg tcttgacgct
     7921 ccccttcgtg gtcagcatcg gttcgcccgg cacgcccgta ttggcgccca gcgctatccc
     7981 ccggtccgtg cgcaccatct ggtcgaaata atagacgccc agcaggtaac gcagctttcc
     8041 ggcgccaccg gacaggcgca gttcctgact gaagaaatgc gaatcgtcgc tgaaattgtc
     8101 cgccgcgacg aaatcgacct gctcctggtc gtcgtccagc gccgcattgt aggaagagtc
     8161 gcgataggcg gtgatggacg tcagcgtgac cgcgtccgac gtccattccg ccgtcagcga
     8221 tacgccctgg ctgtcgcggt ggagccggtt gggccggttg ttgttgacgt gcagcggttc
     8281 cctggacggg aaatcggcgg gataaccggc cagcgcatcc gcctggaaga aggcgggcgt
     8341 gccccggtcg cgcaacccct cccaacgggc gatgaaggac agttggtcgg tcggcgcata
     8401 tttggccgac aggcgccagg tcagcagatc ggtcgacccg gcatccttgc cgcccgacag
     8461 atgcttgtag aaaccatcct gccgggcata ggcgaccgcg ccgcgcaccg acacccggtc
     8521 attcaggcgc atgcccagca cgccttccgc ccggcgatag tcgtaattgc ccgcgtccag
     8581 ccggaaggag gctcccggat cggcgtcggg ctgtttggtc tggacgttga ccacgccggc
     8641 aatggtgttc ttgccatatt cggtgccctg cgggccgcgc gcgatctcca cccggtcgac
     8701 gtccagcaga tgctggacga aattttcagg acggccgata taaaccccgt ccacatagat
     8761 gccgacgccc gtttccagcc cgatattgcg gaccagcgtg gaaatgccac gaatcgagat
     8821 ctggccctgc aactggccgg cgatgccgcc gctgatgtcg acattgggcg ccatgcgggt
     8881 caggtccgta agggtctgca aacctgccgc gacgatcgta tcgcccgaaa tgctggtgac
     8941 ggccaggggc gccttcagca gcgattccgg caccttgcgc gccgtcaccg taatgtccgc
     9001 gcgggaatcc ccgtcatccc ggacttccgc ccaggccgtg ccccccgatg ccagccccgc
     9061 catcgcgccc atcgtcgcgg atgccagaag cgttcttttc caatgcctat aacctaaact
     9121 aatcatcacc cacgaaaccc gttatttttg ttgatgcgcc ctatgtaggg gcgtttggta
     9181 aactgctggt taaacgcttg gtggtaccgg ctccggaacg gagcagcttc gccccggcca
     9241 gaccgaggaa agacgggtcg ccggagcatc tgcttaaccc cgttttaaga cctcacgcgg
     9301 catgacggca gaatgatgcc gcgtgaggaa ccatgagcga atatatcccc agcacacagc
     9361 ttcgcgccgg aagttcgacc accgccgccg atttcatcgc gggcgtcgac gccacgctta
     9421 ccatcgacaa gctggtgaca cgcttcagcc aggcactggg ccttcaggcc gccagccatg
     9481 cctgttacgc ggtcgagggc gacagccggc gcttcctctt cggcgaaacc ggctggtccg
     9541 ggccggtcgc gcagccggaa atcctgcccc ggctgtgctt ttccatcatc ggttgggacg
     9601 agaagcacta tgaggtcgaa atccggctgc tgagcatgct ggaaagccgg gaggagcgcg
     9661 cgaacctgca cgccatggcc acgctgtacc tgtgccgggg catcgccctg ctggatgcgc
     9721 gggacgacgc gaccgcccct tccctcaccg aaacagagct tttctgcctg gaccggcggc
     9781 gggagggttg gtgcgatctg gacattgcag acgcgctgga gcggtcggtt caggccgtga
     9841 aggtgcatat ccagcgcgcc cagggcaagc agcgcgcctg aacgcccttg gccgattgga
     9901 ttttttgccg cgccgatcga ttgcgcgccg caactttccg atgacctccc cttaataata
     9961 tgctaacggc cgaaccgttg catgcgggag acgaacggat ttgatacatc tgatttcgaa
    10021 gaacaattcc gcactttacc aggacgagat cagagatttg caccaagccc gcgcggaggt
    10081 gttcgtcaac cagctgggct gggatctccg ggtcagtgac gggttggaat atgacgaata
    10141 tgatgatgcg cgcgcgagca acatcatagg cttttcgacc gagaatcggg tcgtcatggg
    10201 gctgcgtttc cggcccactg acgattgctc gatgctgctc gaccattttt cgcacgtcct
    10261 gccggcgggc atccgcccca tcgacgacgg gcgcacctgg gaattaagcc ggggcttttg
    10321 cgtcgaacgg ggcatgcggc gccacaatct gcggcggaag gccgcgtgca tgatcgcgcc
    10381 gctggaactg gccctggagg ccgggatcga ccgttgcgtc ggctttaccg acgtgcgcat
    10441 gctcagcttc tgctatggcg tcggctggaa gctgacgctg ctcggctccg ccatggacta
    10501 tggccagggc gaggctgtcg cctatgaggt ggaggtgtcg caggcggcgc tggacgaaat
    10561 gcggcagatg tggggcctgc ccaggccgtc gcacgtcacc gtcgacgacc ttctgccggg
    10621 ggaggaaagc gcgcatgtcg cggcggcccg gatggcccgc gacaatccgg aactgcaaaa
    10681 gatcgccgcc cagccggaga tcggttccag cgcacaaccg tccgccgctg ggcggacaga
    10741 cgtttattat agcggattcg ggacaacccg acaggctgca gggggacatt gatgaattcc
    10801 gattctattc gacaggcacc ggcggaagag attgaaagct ggatcgtcgc gcgtatcgct
    10861 gaaatggtga atgtggcgcc tgccgccatt tccgccgatg cgccgttcga cagtttcggc
    10921 atcgattccg ccaaggcgat ctcgctgatg gtggaactgg agaattggct caacctgccc
    10981 gacgaactgc cgctggaact gctgttcgag gcggaggcga tccgcgacgc ggcggcgggc
    11041 atcgccgaag cggtcgcgga catggcggcg gcccaggcag agggatcggc agcgcgatga
    11101 tgcaggacga actgatcgaa tatggcggct cggccgccgc catccgccac cattatgacg
    11161 tcggcaacga tttctattcg gcgtggctgg acccgaccat gacctattcc agcgccatgt
    11221 gggacgggct gcccaaggac gcgccgctgg aagaggcgca gcggcgcaag ctagcctatc
    11281 atgcggagtc ggtcggcgcg gccgagggca tgaggatatt ggacgtcggc tgcggctggg
    11341 gcggcatgat gcgcaacctg cgcaacagct atggcgtcgc cgaatgcgtc ggactgacgc
    11401 tgagcgagga acaactcgcc tatatcgagc agttgggcga tccgggcatc ggcgcggtcc
    11461 tttccaactg gcacgactat cgccccgaca ggccgttcga cgcgatcatc tccgtcggcg
    11521 cgttcgagca tttcgcccat ccgcagcaga gcgtggacga gcgccggggc gtgtatcgcg
    11581 aattcttcca ggcatgccgc gactggacgg cgggcaaggg gcggttgtcg ttgcagacca
    11641 tcgcctatgg caagatgtcg ccggaggacg ccaatccctt catttcgaac gagatattcc
    11701 cggcggcgga attgccgacg ctggaggata tcgtgatcgc gtccaagggg ctgttccgca
    11761 tcgaaaggct gcgcgacgac gggctggact atgcgcgcac ctgcgagatg tggagcaaca
    11821 agctgcgcgg cgcggtgcgg agcggcgtgg tcgatccggc tgtccatccg gtcgagaaat
    11881 attcccgcta tctgcgcatg tcggccgccg gtttccgcat gcggaagatc ggactgctcc
    11941 ggatcgcctt cgccgcagaa taatatagat cgtcgggttc gcaaccaatg cagatagact
    12001 ttagtcgatc gataatcgac atcgtccttg accatgaaaa cggcgttccg gatcggcccg
    12061 ccctgatatt cgacgtgggc gaagggccgc aggacagcct tacctatgcg caggtggccg
    12121 ccagggtgag gcagcttgcg ggcgcgctgt cggcgcgggg gctggccggg cggcagatcg
    12181 ccctgttatt ctcggcaggg accgatttcg cgctcgcgct gctggcctgt ctggcggtgg
    12241 ggggcatcgc ggttccgctg gcgccggtcg ggcggcggcg ggcgaggctt cagaacatcc
    12301 tgaacatgct gggggatatc aggcccgatt gcgtcatgct ggacgacagc atggccgggc
    12361 agttcgggca ggaactgtcg gccacgcttc ccggcgccgt cagctatctg gaattttccg
    12421 gtctggccgg ggaatcccat cccttcacgc cgctgcggct ggaagcggac cggttggccg
    12481 tgctccaata cacgtccggc accacatcga accccaaggg ggtgatgatc acccatggca
    12541 acatcatcgc caacgagacg atgatcaagg ccgccttctg ccacagccag gattcccatt
    12601 tcgtcggctg ggtgccgcat tatcatgatc aggggctgtt cggtaacata ttgcagccgc
    12661 tgtttctggg gtcgacctgc gtgatcacct cgcccgccgc gttcatcaac aagccgatgt
    12721 cctggctgca actcatcacc cgttatcgcg cgcataccag cggcgggccg aatttcggct
    12781 atgacctgtg cgtcgatcat gccacgcgcc ggggcatgcc ggaactggac ctgtcgagct
    12841 ggcgggtcgc cttcaacggc gcggagaggg tgcggcccag cacgatggac cgtttcgccg
    12901 aatgtttcgc cgatgccgga ttcgacagac gggccttcct gccctgctat gggctggcgg
    12961 aatcgacgct ggtgaccatc gccgtgccgc cgcaaagcga gccgatggtg cggacctatg
    13021 acagccgcgc cctggccgcc gggcgggcgg aggaaagcgc cgagggtatc gacctggcct
    13081 gctgcggtcc cgccatggct ggcggagagg cgcggatcgt cgatcccggt acgggcgagc
    13141 cgctgcccga cggcgcggtg ggcgaaatct ggctgcgggg tccgcatatc gcggccggct
    13201 atctgaacaa tgcggcggcg accgaggaga ccttcggtgg gcggctggat gagggcgggc
    13261 cgtttctgcg cacgggcgat ctcggctttt ccacggcgga cggctttttc atcgtcagcc
    13321 gcctgaagga cgtcatcatc gtgcgcggcc gcaattacgc gccgagcgat gtcgagcata
    13381 tctggtcgga aatttccggg accgtggaac aggccagcgc cgccgccgtg gagatggagg
    13441 tcgacggcgt gcagcacatc gccctgatcg cggaattgaa gcgggacgag gcccggaacc
    13501 tctccgtcga gactttgcgg gaaaccgccg ggaaactgcg cgccatcgcc atggaacggc
    13561 tggaactggg catcaccgat ctggtgatgg tgcccgccag cgcgattccc cgcacgacca
    13621 gcggcaaggt gcagcggaaa caggccgccc ggctgctgat ggaaggcgaa ctcgctgtcc
    13681 tgggcatgac ggggccgttg gagcacaatt tcaagccatt gcggcagaag gcgacggctg
    13741 gcggctgacc gcccgtgcat gcggcgcgat gcggaaggcg gactcgttcc ttgatgcccc
    13801 ggccggggaa gcgtaaactc tcgctcgacc ttaaccgcat ctggtggagg atcgcccgat
    13861 gattcatgcg tctttgccca tgcgctggac tccagcaatc tctctgctgc tcgcggcgac
    13921 cgccggtccg gccttcgccc agcagatgat cctgccggag ggcatggcca tccaactgga
    13981 gacgcggcag gcgctttcct ccaaatcggc gcgggtcggc gatgcggtcg aactggcggt
    14041 ggccaagccg gtgacgatcg gcggcgtgac gctcatcccg gcgggcagtc ctgcgacggg
    14101 tacggtcagc cgggtcaggg acaatggcct gttgggccgg tccggcaagc tggatatcaa
    14161 ggttagcgcg atcaagctgg gcgggatcga cgtgccggtg cggggtcagc gcaacgcgca
    14221 gggcaaatcc ggcacgctgg gcgcggtggg cgcgggcatc gtcttcctgc cgctggcggt
    14281 gatcatccgg gggaaggacg tcaaattgcc tgcgggcacg ccgttcgagg tctatgtcga
    14341 ccgggaggtt tcgattggac cggccgtccc tgccgcgccc gccgccgtct cgtccgatag
    14401 ccccgctgca acgagcgtca taaggacgat agatcccaat caggccatcg gcgcggaatg
    14461 aggtgcgccg tcaggccgcg ccatccggcc ccaggcggag cgcgctggcc cggacgaata
    14521 tcgcatggat caccggatcg gtgtcggaaa tccgcttcgc cacgtggaaa tcgatgggcg
    14581 cgaggggcgg catcccctcc agttcgacca gcgcgccgct cgtcaggtcg tcgcgggcca
    14641 tgggttctgg aaaaatgccg atgccgccgc ccgccttggc gatgtcgatc atcatccggg
    14701 cgttgttgca caggttgagc gactgatgcg cgatccgcga agcggcgatg gcgtcgcgca
    14761 tgcgcccgta gatcggcgaa tggctggcca gcgaccatat cgggatcgtg cggtccagcg
    14821 catcgccatg gaaagaagcc gcgacggcgg ggctggccag ccaggccagg cgcaccgccc
    14881 cgatcggact cgactggagc gaagggtgcg ccagcggccc ggccgcgaac gcgatgtcgg
    14941 tgcggccgac cagcaattgc tggatcagat tggcggtcag gtcgatttcc agttccaggc
    15001 tgacatgcgg catatccgcc ttcaattggg cgacgaaggc aggcaggcaa ctggcggcgg
    15061 caatttcccc ggccccgacg cggaccacgc cggtcgcttc ctccaacccg ccgcaacgca
    15121 gcaacatgct ttgcagatcg ctccagagcg gcccgcaatc gcggacaagc tggcgtccgg
    15181 cggcggtgaa cgacatggtc cggccctctc ggcggaacag gcgggcgccc agatggccct
    15241 ccaactcccg cacgcgcgcg gaaatggcgg gctgcgtggt gttcagccgc tccgccgcgg
    15301 cggcgaaagt gccgagccgg tcgatccaga gcagggtctc cagatggaag aggccgatgc
    15361 gattgataga cattcatttt gattagagca aaaaacaaat cattagaaat gataaattcc
    15421 ttccgccaga gtggcgtttc caaggagagg cgagctgatg gtcaaaaagc tatattcgga
    15481 tgccgcaagt gcgttggagg gattgctctt cgacgggatg catctgtgcg cgggcggttt
    15541 cgggctgtgc ggaattccgg agcggttgat cgacgcgatc cgggattcgg gggtcaggga
    15601 tttgaccatc gcctccaaca atgccgggat cgacggcgag gggctgggca agctgctgcg
    15661 cacgcggcag gtgaagaaga tgatctccag ctatgtcggc gagaacaagg agttcgagcg
    15721 gcaatatctg gcgggtgaac tggaagtgga gttctgcccc cagggcacgc tggccgagcg
    15781 gtgccgggct ggcggcgcgg ggattccggg cttctatacc aagacgggcg tcgggaccgc
    15841 cgtggccgag ggcaaggagg tcaagaattt cgacgggcag gattatatcc tggaacgcgg
    15901 catttttgcc gatgtggcga tcatcaaggg gtggaaggcc gatgagagcg gcaacctgat
    15961 cttccgcaag acggcgcgca acttcaacca gcccatggcg acggcggcga agatctgcgt
    16021 ggccgaagtc gaggaagtgg tgccgaccgg cagcctcgat cccgacgcga tccatctgcc
    16081 gggcatctat gtgaagcgca tgattgtcgg cgcgccctat gacaagaaga tcgaattccg
    16141 caccgttcgc cagagggaga ccgcatgatg gcccaggaaa ccaaaggcca ggaaaccaaa
    16201 ggccagaaaa ccaaaggctg gagccgtgat gaaatggctg cgcgggcggc gaaggagttg
    16261 caggacggtt tctacgtgaa tctgggcatc ggcattccga cgctggtggc gaaccatatt
    16321 cccgcggggg tggaggtgac gctccagtcc gagaacggca tgctgggcat cggccccttc
    16381 ccctatgagg gcgaggagga cgccgacctg atcaacgcgg gcaagcagac gatcagcgaa
    16441 ttgccgcagt cggtctattt ctccagcgcg gacagcttcg cgatgatccg gggcgggcat
    16501 atcgacctga ccgtgctggg cgcgatggaa gtgtcggaaa atggcgacat cgccaactgg
    16561 atgatccccg gcaagatgat caagggcatg ggcggcgcga tggacctggt cgcgggcgtc
    16621 aagaagatca tcgtcgtcat ggaacatacg agcaaggatg gcagccccaa gttcatcccc
    16681 gcctgcactt tgccgctgac gggcaggaat gtggtcgaca tgatcattac cgacctggcc
    16741 gtgttccagc ggcccgacca tgacagtccg ttcaagctca tcgaatgcgc tccgggcgtg
    16801 acggcggagg aaatcgccgc caggacgagc gcgcattata cggtttaggg ccgttcgacc
    16861 gggcttgccc tgttcaagtc gaaccatatt cctgcaaaac ggcaagcctt ccgcctccat
    16921 ctaggttaac atgcacttcg cccgtccatg ccggactcga tccggcatgg ggggccggag
    16981 aggtgtcata tgtggcgccg gagcagagaa tggggcctcg aaaggcggcg cgcgcgcgcg
    17041 cttgccgctg cgcctttccc ttgtccgcgc tgggcgctgt tctgctgcct gcttctcttc
    17101 ccttttccat gcccggcggg accgttcgag gacgccgccg ccgcctatcg gcgcggcgac
    17161 tatgccaatg ccatgcgcct gtaccagtcg ctggcggatg gcggcgatcc gcgtgcgcag
    17221 aacagccttg gccgcatgta cctgcggggc cagggcgcag gccgggatta caggcaagcg
    17281 atgaaatggt tccgccgggc cgcggcgctg ggggtggcgg acgcccagtt ccatctgggc
    17341 gaaatctatc tgcgggaatt cggcgtcgag caggatctgg tggaggcggc gcgatggtat
    17401 accagggccg ccgaacaggg gcatatcggc gcgcaattca ccctggcggt cctctacacg
    17461 ataggccggg gcgtcagcag gagcccgctg aaggcggtct attggttcga acgcgccgcg
    17521 tcccagggca atgccgcggc gcaggtgcag ctcggaatca tctatggcgc gggtcagggc
    17581 gtggcccgcg attccgtggc cgcctataaa tggttcgccc tgggccaggc caacgcccgc
    17641 gagtcgaagc tgcgcgccaa ggcgagccag aatatgaacc gcctgtcgcg cggcatgacc
    17701 ccggcgcaga tcgccgaggc gcagcgccag gcccgcgaat ggcaacccgt tccagcacgg
    17761 ggcggccagt catgaacaaa cccccgcccc tttcccccgc cccccctctc tcgacggcga
    17821 acggaccccg aaactggctg aagggcggcg tcaaatatgg gttcgccctg atcgtcggga
    17881 tcgtcagcct gctgctgacg ctgggcgtct ggcaatggct tgtcctgggc caaagccggt
    17941 cgaccgaaac cgaattcagc ctggaggccg agcaacgcgc agaaggcatc aagcggcaat
    18001 tcttctcgga aaccagcgtg atccgcgccc tgctgggcta ttatcaggcg tcgcaggatg
    18061 tctccccgga agagttcaag gcgtttgcaa aagtgtatct gaccgggctg tccagcctcg
    18121 attccgtgca atgggcgccc tatgtccccg gcggagagcg ccgggactgg gaggaaaagg
    18181 gcgcggcttt ccggttcacc caggtcgatg cccatggcgc ggccgtcggg gcggatcggc
    18241 gcggcagcta tttcccgatc gtctatgcgg aatcggccac gggcggcgcg ccggagacac
    18301 tgggtttcga ctggggatcg gacccgttcg cgcgtggggc gatgctggcc gcccgcgaca
    18361 gcggagagat caacgccgcc gcccatatcc gcctgccgcg gatggatgac ggcacgcccc
    18421 gcatcgccct gttcgccccc gtctatgacg gcggggagca gatcgccgtg gatcagcgcc
    18481 gcaagcatct caaagggttc gtcgtcgccg tgctacggat cggcgacgtg atccagggcg
    18541 cgatcgacct gatgcccagg aagggcgtcg acctttacct gctggattcc tcggccccgg
    18601 cggcgcagcg ggtgctgctg tcgatcatgg cgcccggcag caaggcgaag cggcggcccg
    18661 gcgccggtcc ggccatggat tcggacctgt tccattccag ttcgctggtt atcggcaaca
    18721 gcgtcttcac catctacacc gccgcgaccg acgcctatgg cgacaagcgg ggcgcgacca
    18781 cgcccaccat cgcgctggcg ggcggcctgg ccgtcaccct gatcctcttc atctacctcg
    18841 tctcgctcgc caaccagcgg gcgcgcaccg aacaggtggt ggcgcagcgc acggcggaac
    18901 tgcgcggcgt caacatgcgg ctggaagaac ggacgatcca gttggaggaa tccgagaccg
    18961 aattgcgcgc cgccaagaac cgggcggagg aagccacccg cgccaagagc cagttcctgg
    19021 ccaatatgag tcatgagatc cgcaccccca tgaacggcgt gatcggcgcg gcggaactgt
    19081 tgaacgacac aaggctgaat gcgtcccagc gcgaatatct gaccatgatc acgcaatcgg
    19141 cggacgcgct gctgcatctg atcaacgaca tcctcgactt ttcgaagatc gaggcggggc
    19201 ggctggaact ggagcatgtg gccttcagcc tgcgcgacga actggccgac acgttgcagg
    19261 cctttgccgg gcgcgcgacc gaaaagggga tcgaactggc ctgtcatgtc gcgctggacg
    19321 tgccggacgc gctggagggc gacccccacc ggctgcggca ggtgatcatc aacctggtcg
    19381 gcaatgcgtt gcgcttcacc gaacggggtg aagtggtcat ggatgtcgcg atccagtgga
    19441 tggagcagcc gcagatccgg ctgcgcttcg cggtcagcga caccggcccc ggcatagcgg
    19501 cggacaagcg gcaactgatc ttcgaggctt tttcccaggc ggacacttcc ttcacccgcc
    19561 gtttcggcgg caccggcctt ggcctcacca tcgcatcgca actggttcag ctcatgggcg
    19621 ggcggctgga actggacagc gcggtcggcc ggggcagcgt ctttcatttc accattccct
    19681 tcgccctggc gcagggcgaa ccggcccgcc tgcccgccga acagccgtcg ctgcatggcc
    19741 tgcccgtgct gatcgtcgac gacaacgcca ccaaccgccg catattggaa gagatgatcc
    19801 gcggctgggg catgaagccg ctggcggtcg agagcggccc caaggcgctg gccgcgctgc
    19861 gcaacgcggc agggatcggc cgtccgctgc ggctggtgct gctggacatg atgatgccgg
    19921 acatggacgg atttgccgtc gcgaaggaaa tggcgcggag cggcgaagcc cagcgtccgg
    19981 cggtgatcat gctctcctcc gcgcggaagg acgaggtggc ccggcgcaac tgggcgaccg
    20041 gcatcgccgc cttcctgctg aagccggtgc gccagtccga attgctggag gccatttttg
    20101 ccgtgctgaa ggtgacggtg cgggaagaaa ccgccctgcc cgaacccgtg ccggacgacc
    20161 ggccgtcgct ccatgtgctg gtggcggagg acaatgccgt caaccagcgt ctggcgctgc
    20221 gcctgctgga aaagcgcggg catcgcgtga agatcgtcgg cgacggcgcg caggcggtgg
    20281 aggcgctggc ccaggaccgt ttcgacgtgg tgctgatgga tgtgcagatg ccggaaatgg
    20341 acggtttcca ggcaaccgcc gccattcgcg aacgggaacg cggccagggg aaacatatgc
    20401 ccatcatcgc catgacggcg catgcgatgc gcggcgaccg cgaacgatgc ctggcggcgg
    20461 ggatggacga ctatatctcc aaaccactgc gggcggagga tttctacgag gttgtggagg
    20521 ggcggttcgc cagcgcggcg aagccccata gcgaggaagg gtccaggcca tgagcacgct
    20581 tcttgattgg accagggcgc ttcagaatgc cgatggggac gagggcctgc tgatcgaact
    20641 ggcgggcgtc ttcatcgacg aatgtccgga gatgatgcgg caggtccgcg ccgccatcga
    20701 ccgcagggac gcgcgggagc ttcggcgcac cgcgcacagc ctgaagggat cggcgcatat
    20761 cttcgccgcg tcggaggcgg gggcagccgc ct
//
