LOCUS       NZ_CP102665            22465 bp    DNA     circular CON 07-JAN-2024
DEFINITION  Sphingobium sp. JS3065 chromosome 2, complete sequence.
ACCESSION   NZ_CP102665
VERSION     NZ_CP102665.1
KEYWORDS    RefSeq.
SOURCE      Sphingobium sp. JS3065
  ORGANISM  Sphingobium sp. JS3065
            Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
            Sphingomonadaceae; Sphingobium.
REFERENCE   1  (bases 1 to 1017992)
  AUTHORS   Li,T., Xu,J., Xu,Z.-J., Xu,Y., Spain,J.C. and Zhou,N.-Y.
  TITLE     Molecular mechanism and evolution of 1-nitronaphthalene catabolism
            in Sphingobium sp. strain JS3065
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1017992)
  AUTHORS   Li,T., Xu,J., Xu,Z.-J., Xu,Y., Spain,J.C. and Zhou,N.-Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2022) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 800 Dong-Chuan Road, Shanghai,
            Shanghai 200240, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. v0.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio RS
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/07/2024 05:42:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,942
            CDSs (total)                      :: 4,873
            Genes (coding)                    :: 4,751
            CDSs (with protein)               :: 4,751
            Genes (RNA)                       :: 69
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 122
            CDSs (without protein)            :: 122
            Pseudo Genes (ambiguous residues) :: 0 of 122
            Pseudo Genes (frameshifted)       :: 40 of 122
            Pseudo Genes (incomplete)         :: 96 of 122
            Pseudo Genes (internal stop)      :: 12 of 122
            Pseudo Genes (multiple problems)  :: 23 of 122
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:10:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 363228
            Orig. end                         :: 385693
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102665.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22465
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22465
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22465
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12465](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12465)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            456..1844
                     /locus_tag="NUH86_RS19035"
                     /old_locus_tag="NUH86_19040"
     CDS             456..1844
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012955.4"
                     /locus_tag="NUH86_RS19035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19040"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_267252879.1"
                     /transl_table=11
                     /translation="MNPIAPKRFEITSFSSTYIPEVSKRVDVDADVPERITMKLIGVIV
                     PFLMMLMSATSAFAQPEVSPSERVRRNVVVRVEPNAASQPIGALSPGDSVSVVGDAPGW
                     HQVRLSDGRIGFVSKAWTIIRSGPEPLIDTAALKLHVIDVGTGLAVFVEGPSFTILYDG
                     GSQDDLADGPDNRILNYIQAVRPGLQTIDHLILSHPHKDHLELLPDIFDRFMIHNVWDS
                     GAVNRTRGYCRFLKKVAAEPGVQYHNAIATGGTHRVVFTGKTCSGEVVLPQAAMMTASP
                     VALGPGGTMSILYRDASKHHDPNENSVVIRLDYAGRRILIAGDAEGGARKAPSQPADAN
                     SVEGKLIACCSADLRSDVLVVGHHGSMTSSRQEFLDKVQASTFIISSGPHPYSKVVLPD
                     VAIEDELRARGALFQTDLADDDCPASEAKIGPDNDESPGGCDNVIVTVSSTGQVATGYF
                     READ"
     gene            complement(2089..2985)
                     /locus_tag="NUH86_RS19040"
                     /old_locus_tag="NUH86_19045"
     CDS             complement(2089..2985)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013849041.1"
                     /locus_tag="NUH86_RS19040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19045"
                     /product="MucR family transcriptional regulator"
                     /protein_id="WP_267252880.1"
                     /transl_table=11
                     /translation="MADETPNEFTTLTVQLLSAFVSNNTVPADGLADLIKSTRAALATN
                     PVAIQVEPEAQGYVPAVSIRRSTASRDFILSLIDGKPYKTLKRHLAQHGLTPDQYRDRF
                     NLPKSYPMVAPAYSDARRAVAEKLGLGRKPTKITKNGKEDAQPKDAASKINPAPPTTVV
                     AAEAADVGIKKGKADRAKTASKTTKIAAPETASAKPGKKEPSADKQTARKRLSIATPTD
                     DKPAPAPAPKAGRKDQAVSLGVEAETIKPKRTGKAPSSPKAAKPAAKPKSSAPTVKAGT
                     APVTDGGELKQAVAGKA"
     gene            3467..3997
                     /locus_tag="NUH86_RS19045"
                     /old_locus_tag="NUH86_19050"
     CDS             3467..3997
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1126:
                     extracytoplasmic-function sigma-70 factor"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019052713.1"
                     /locus_tag="NUH86_RS19045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19050"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_267252881.1"
                     /transl_table=11
                     /translation="MDVVLLADEEIDTPLLAQTYRTQAPGLLRYFKRQTRNSDDACDLM
                     QEAFVRLTAHMRKTPLSHPASYLQKIARNLLVDRIRLSKRAEAAFGKQTSEDVEIAVEP
                     DQGLAIEGVDTLRLYRQAVAALPQKTRQVFIMQRAKGMTYKQISEELGISIPTVQYHFG
                     RALARIAQALDGE"
     gene            4021..5001
                     /locus_tag="NUH86_RS19050"
                     /old_locus_tag="NUH86_19055"
     CDS             4021..5001
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016648.4"
                     /locus_tag="NUH86_RS19050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19055"
                     /product="FecR domain-containing protein"
                     /protein_id="WP_267252882.1"
                     /transl_table=11
                     /translation="MRDEAAAWFAAMRGPAAADRKMEFDAWMAASPSHRAAYARISEIY
                     NLGKCLEFGHEPAIPAHRRQRRQLSVLAAALCLGIISLAAFVWKPLHPGPSSDASRSMA
                     VAANASNPMQTAIGEIRRIKLADGSTLTLDTDSLVRAEFTDSARTLHLERGQARFDVAH
                     EARPFTVMAGVLSVTAHGTVFDVSARSNGRSAVHLLRGSVEVTQRAGVEGRRILTTKML
                     APGQAAETGSAGLNLLKQFPTNPAGTDWPSLLRQFDKIELGELIQEANRYSRVKIRPPA
                     PEVAAMRASGTFRINDPQRLASNLALLLDLRARNEPDGTISITAQ"
     gene            5100..8045
                     /locus_tag="NUH86_RS19055"
                     /old_locus_tag="NUH86_19060"
     CDS             5100..8045
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1082:
                     TonB-dependent siderophore receptor family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012801.4"
                     /locus_tag="NUH86_RS19055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19060"
                     /product="TonB-dependent receptor"
                     /protein_id="WP_267252883.1"
                     /transl_table=11
                     /translation="MRQIFHGLASSVFSIAAITTASYAPIAISQSDQRIELHIAEQDLA
                     ASLQALGAATGREILFRPEAVAGRTAPAIEGHFTATQALTILLRSSDLRFRENGRSLVI
                     RGRSEASAALSDGADAANTLFVTGSRIRGADAPGSNVIRLDRKAIGESGYASAQQILQS
                     IPQAYGGGANEATSGATGASGANLNASYGSSINLRGLGPSSTLVLLNGNRPALGGSGGV
                     FADISMLPVSAIERIEVLPDGASAIYGSDAVAGVVNLITRRKFEGLETGLRYGTADGDF
                     SEIQASQVAGTKWSSGRAVLAIEYYRRGSLAADDRDFATQDLRRWGGSDYRVQFANPGN
                     IVAGGKTYAIPSGQDGSSLVASDLVAGSLNRQDGWEQADLLPRQTRYSVYGRVEQDVTD
                     GITLDIEGLYARRSFSKRVNPAGYQSSITVTPDNPYYIDPIGTGRAISVRYDFTDELGP
                     RTDQGKVEALGFNGGGTIALGGWAIDIRGTYGKQIENFGTINLPNTARLAVAAASSNPS
                     IAVNLLGDGKVNSATVLDYIRGSTHSRFASTIWSGAVRGDGPLVNLPGGQARLALGAEH
                     RDERFKSRSVSDQSRLEPYVFTGTQGARNIEAVYGEIFVPVIGAANALPAFQSLSLSAA
                     VRHERYNDFGSTTNPKFGLSWKPVSGLELKGSFGTSFRAPGFVELRQTPDSDVYFIYPV
                     SDPQSPTGTSNVMYYRGNKTGMKPEKARTFTLGFVLEPALLPGLRLSSSYFDIRYKDQI
                     VDLTSALLQMLNNRATYAALINDNPSLEMLQAAINSPNFIDYLGLQAADVDVFIDARTQ
                     NLAVVRQKGLDFDAQYQFPAGSGTARLGIDGTYLFRFTRAASASAPAIDILNSINNPVD
                     LRLRAHAGWTSGPLSALTSLNYVRGYTNSIVSPAEHVDAWTTIDAQLSYRFENKTGVLQ
                     DLAVALSATNLFDKDPPYAAFSFNGITAVGYDPQNANPLGRVVSLQLTKAW"
     gene            8047..10116
                     /locus_tag="NUH86_RS19060"
                     /old_locus_tag="NUH86_19065"
     CDS             8047..10116
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033523.0"
                     /locus_tag="NUH86_RS19060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19065"
                     /product="Atxe2 family lasso peptide isopeptidase"
                     /protein_id="WP_267252884.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 2.8e-18, bitscore:
                     61.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLPYCLVAVLFAAVGALPSAAAALCSPPPTRAEQSATNGANVSP
                     EDLLGLWDFGDGGSSPLNASHIALSPNKKQLAVQMRRADAATNRYCMALVIIDRSGQSA
                     PIIADQGGDFIKAQFSNRRLAGFPIGLPMPLTPRWSPDGHHIAYVRRDQGQTRLWIANA
                     DGSGAEAATSGDLPISDLRWSADGRHVLLAADTNRLEAERRIEEEGLSGFHYDYRIWQA
                     ARALPFPPGPYPPIYYQVDRETKQLMSLPADAASKAFGSRGEGIPANARLGTFSDDGNA
                     AAWVEREQPDQLRSPSRLHAVVDGVPIACQSEACAGELLGIWWTDRREILFLRTEGPAD
                     RSHLALYKWHPRRGRPTLLLRTEDLILGCQAGKGELFCGYERSLEPRRVVAISARDGAV
                     STVYEPNPDFARHRFGAVQRLYWKFQGGEAFGDLVLPPDYRNDRKLPLIVVQYTSRGFL
                     RGGTGDEYPILPLAAAGFAVLSFQRPTDYANRIPAANIAEFSQNNVTGWADRRHVLNAL
                     EAGVSQLIDRGLVDPARIGISGLSDGASTVQFALVNSSMFRAAAVSSCCEDPSNYDSAG
                     EEYYRDLVSWGYPPRGTDGRKFWQRYSLLQNADKIAAPILMQLSDDEFRLALPAYHALE
                     AAGKTVDMYVFPDEHHIKWQPAHRLAIYRRSIAWFRGWLTPQGDPASPSAGERP"
     gene            complement(10001..11818)
                     /locus_tag="NUH86_RS19065"
                     /old_locus_tag="NUH86_19070"
     CDS             complement(10001..11818)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="NUH86_RS19065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19070"
                     /product="asparagine synthetase B family protein"
                     /protein_id="WP_267252885.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.4e-25, bitscore:
                     85.7, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDFILCPSAGPAIGIARRALADLSLTDDFSETSIDANYRLFLRG
                     RVEISSDRRLVIIGEAFDAAGGRLSRESLDRAAHSADTLETVASRHWGQFVAVTVDAQT
                     VRFYRDPSAGQACYMCRVGSAFFAASSVDLLRLVTGQDFEICRDGIIRALAYRDLRQDR
                     TALKSVRELTPGCTASDQNEEVRYVWQPLVDLEVGRALPHEEIAERLERVLRVAVRAQT
                     NGASRVMLELSGGLDSSLLAMLLADMAIDFTAVTYVGPDAREDESDFARAVCAHLGRQW
                     RGSVLSADHIRLHESAAAHLAWPSARLFTQLFDQAADRAMDELGCDMIMSGGGGDGTFC
                     YLPSSAPLIDCLGSWKTMLNSPAVVHDLARAHDTTSAEIIWRALRRMSLPHRLSWKRDG
                     SFLSRDTRRSLSRRAYHRGIDLGCAPRGKCDHLKHMIGIHNHLDAYSAPRHDALRFPLV
                     SKPVVETALQIPTWQWFEGGRNRAPVRRLLADRLPPMISGRRSKGGFDAVIRDIFKERS
                     GEMKAHLHDGWLATEKIIDVDAVDEEFFRFQESGSGGINRLMVLWDTEMWVRAVRRRKV
                     TRGLLEGSAIRETRQSIAGRSRGDAPAAI"
     gene            complement(11815..12465)
                     /locus_tag="NUH86_RS19070"
                     /old_locus_tag="NUH86_19075"
     CDS             complement(11815..12465)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="NUH86_RS19070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19075"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_267252886.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 9.9e-10,
                     bitscore: 34.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF13471 (E-value: 1.5e-15, bitscore: 53.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLYATPHFHHCLVDGRVVALDMRTTRYFLIHGASGEALIQWEAGA
                     ESRHSDETFDDLMAKGYVSREQAGNRRLEACAAKPLKSRAEICVSSANRAEYLQIAWFL
                     ATTRLRIATGSLARTLEPMRKRAGQMPVREQQVVMDRVGRFTACRPAIPLSRVCLLDSV
                     ALYHFVGDSMTELVFGVSLDPFAAHCWLERDGWLLNDEIDHVRRFTPIMRCRA"
     aSDomain        complement(12271..12456)
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_NUH86_RS19070_Lasso_Fused_RRE.1"
                     /evalue="3.10E-11"
                     /identifier="RREFam003.1"
                     /label="NUH86_RS19070"
                     /locus_tag="NUH86_RS19070"
                     /protein_end="65"
                     /protein_start="3"
                     /score="34.2"
                     /tool="antismash"
                     /translation="ATPHFHHCLVDGRVVALDMRTTRYFLIHGASGEALIQWEAGAESR
                     HSDETFDDLMAKGYVSR"
     gene            complement(12511..12642)
                     /locus_tag="NUH86_RS19075"
                     /old_locus_tag="NUH86_19080"
     CDS             complement(12511..12642)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NUH86_RS19075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NUH86_19080"
                     /product="benenodin family lasso peptide"
                     /protein_id="WP_267252887.1"
                     /transl_table=11
                     /translation="MERIEDLSDDFVDLGNAAFETKGAIAGEPSDGVGYRLNGMADE"
     CDS_motif       complement(12577..12642)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MERIEDLSDDFVDLGNAAFETK"
                     /locus_tag="NUH86_RS19075_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(12511..12576)
                     /prepeptide="core"
                     /locus_tag="NUH86_RS19075_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="3.60"
                     /molecular_weight="2061.2"
                     /monoisotopic_mass="2059.9"
                     /core_sequence="GAIAGEPSDGVGYRLNGMADE"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MERIEDLSDDFVDLGNAAFETK"
                     /leader_location="[12576:12642](-)"
     misc_feature    complement(12628..12641)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.67"
                     /tool="antismash"
     gene            complement(12798..13454)
                     /locus_tag="NUH86_RS19080"
                     /old_locus_tag="NUH86_19085"
     CDS             complement(12798..13454)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012610.4"
                     /locus_tag="NUH86_RS19080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19085"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_267252888.1"
                     /transl_table=11
                     /translation="MAPEPLTAERIYRRLKADILDGVFPPGSQLIVQNAAEHYGVSISP
                     VRDGAHRLVGERLLGLNVGGGFTIPQLDAQVLRDLYVWHGYLVRHALKANSPVAGEPGP
                     IAILERSGPHHPKDIRDATAALFGRIGSRPGNQVHLHAVLAAGELLSVARLHEPSVVKN
                     VEEELLAIWNLTRSGQDAALRDAIWAYHRRRIRRASAIAHRISAVPPSSDTAGRS"
     gene            complement(13467..13886)
                     /locus_tag="NUH86_RS19085"
                     /old_locus_tag="NUH86_19090"
     CDS             complement(13467..13886)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014076296.1"
                     /locus_tag="NUH86_RS19085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19090"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_267252889.1"
                     /transl_table=11
                     /translation="MPTRRLQTKDNVLVLSRIKEISGKRIEERRRRDRITQPQLARAAG
                     VSVRWLREIEAGNPKSKLDEHLACAHRLGLSTTHIMIPLLLMERRMSIPEEYLVEEDLS
                     ELEDRCIALVYEHSQAAVTRRRSSFFGPGDDGEPS"
     misc_feature    13970..13985
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.08"
                     /tool="antismash"
     misc_feature    complement(13973..13988)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.79"
                     /tool="antismash"
     misc_feature    13981..13995
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: strong, score: 26.19"
                     /tool="antismash"
     gene            complement(14048..14464)
                     /locus_tag="NUH86_RS19090"
                     /old_locus_tag="NUH86_19095"
     CDS             complement(14048..14464)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NUH86_RS19090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NUH86_19095"
                     /product="hypothetical protein"
                     /protein_id="WP_267252890.1"
                     /transl_table=11
                     /translation="MNGKRSRAYRLTLSERGLELYLSVHLRLCILAQDLLPYGATLQAA
                     IDLLEQRDCDEVAAEMLDNRLDIYFGKCEHFVGGSPAIGRSARAIRERLSQTGLMHAPQ
                     IGRIYIAGLGVLGASENRELTSWVARLARERARS"
     misc_feature    complement(14708..14726)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.7"
                     /tool="antismash"
     gene            14805..15113
                     /locus_tag="NUH86_RS19095"
                     /old_locus_tag="NUH86_19100"
     CDS             14805..15113
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NUH86_RS19095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NUH86_19100"
                     /product="hypothetical protein"
                     /protein_id="WP_267252891.1"
                     /transl_table=11
                     /translation="MGRGIPIGAPTLVILMAATMPAMAAKGQAMVKARVPTDWVQPLAV
                     RQQGGEFIIEAVTLGQIPPAPAMTVPLGRSIRFDPALLARPFHDRKGNHDVMPRTDR"
     gene            15088..15876
                     /locus_tag="NUH86_RS19100"
                     /old_locus_tag="NUH86_19105"
     CDS             15088..15876
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010336445.1"
                     /locus_tag="NUH86_RS19100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19105"
                     /product="DsbC family protein"
                     /protein_id="WP_267253001.1"
                     /transl_table=11
                     /translation="MSCHARIAKTLAIALIAGAAGVVNAAPAEPATDPVALDAVAAKAQ
                     ASLRQSFTNLQFEDFGPAPVKGPVFQASAGGRILYYAPDSEHLLFATIYDRNGVNLTAL
                     AQDASARKKLGALGPNQALTIGPPGAPTVIEFTDPDCPYCRALDRFWAAKAAEGKPVRR
                     QIYFVSGIHPQAASKAEHILCSKDQAGAFRATYAGDAPKPLTTCKEGAALVARNAEAVK
                     AMGISGTPTLILDGRVISGFQQAEIEAWLEEKQAPKKPPS"
     gene            16061..16405
                     /locus_tag="NUH86_RS19105"
                     /old_locus_tag="NUH86_19110"
     CDS             16061..16405
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009823913.1"
                     /locus_tag="NUH86_RS19105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19110"
                     /product="hypothetical protein"
                     /protein_id="WP_267252892.1"
                     /transl_table=11
                     /translation="MLKLASLPAPSRNRMRRLSFASADAVGTLLIAMTLASAAHAFQAP
                     AAGDLGYDIYDIVVNQGVKGPLGFVGGVAAFLFGVSRLFSNIMIGIPTIVAAVCLIRAD
                     SILQTFGMMV"
     gene            16532..16798
                     /locus_tag="NUH86_RS19110"
                     /old_locus_tag="NUH86_19115"
     CDS             16532..16798
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014076300.1"
                     /locus_tag="NUH86_RS19110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19115"
                     /product="type IV conjugative transfer system protein TraL"
                     /protein_id="WP_037544084.1"
                     /transl_table=11
                     /translation="MDERLPQFLHKPVQILWFDAQEFILVVSTIFVAVIVGGYVGWSLL
                     GVLLLFIPWKRTKPRGFMPHLAWRWGLLKLPRYPGPTQTRFCE"
     gene            16807..17442
                     /locus_tag="NUH86_RS19115"
                     /old_locus_tag="NUH86_19120"
     CDS             16807..17442
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009823915.1"
                     /locus_tag="NUH86_RS19115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19120"
                     /product="TraE/TraK family type IV conjugative transfer
                     system protein"
                     /protein_id="WP_267252893.1"
                     /transl_table=11
                     /translation="MFGRSSAREPSDPLRDKPASFGIHRYLQGSSNLFEENRLLKFSVL
                     GLFGITAVLGIALYSTSQNQRTIVVPFGAGGDLYVTGGKPSPAYLRTMTRNIVALSGTY
                     SALSADRQFEELLSIVHPTAYNGIRDSLNAILDELANNPTLSIATYIRPDQPVTWTDRQ
                     ILVPVEKVRVIGGVIRKFRGNLRIRYTIDAGRFWLLSLSEENFDAELR"
     gene            17426..18193
                     /locus_tag="NUH86_RS19120"
                     /old_locus_tag="NUH86_19125"
     CDS             17426..18193
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009823916.1"
                     /locus_tag="NUH86_RS19120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19125"
                     /product="type-F conjugative transfer system secretin TraK"
                     /protein_id="WP_267252894.1"
                     /transl_table=11
                     /translation="MPNFGKRLGAPAALITACLPVPTFAQAIMALPDQISSIRLSNRDI
                     NHLICQGGEIEDVKFSAEKAIAVEKAGADAWVKFLVKESDDAGQVTRSFVTTPSEFFVT
                     CNGAIYPLYAEPTDIPAQTVTLAPGASQRARANGELLGPLVEEERAVSITLSMLQDRVP
                     ASFTEIAVSPRPLALSAAPALRITERRRVAIEGTGLSASEYWIEASTDNEIDERIFLDA
                     SLGARIFSVTLDRLSLKAGETARLILLRRGETL"
     gene            18190..19575
                     /locus_tag="NUH86_RS19125"
                     /old_locus_tag="NUH86_19130"
     CDS             18190..19575
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006951377.1"
                     /locus_tag="NUH86_RS19125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19130"
                     /product="TraB/VirB10 family protein"
                     /protein_id="WP_267252895.1"
                     /transl_table=11
                     /translation="MSGPGDKGGEKPMGAQPTGSRPDAPTQRPHAGIKGYSRPPKRRDG
                     ASGEPDDRAATEVRGPALLDLKARWALLSARQQLRARQAGVGVVIAMFGYGLYTASTGS
                     KDEAPAAPVASRLDMGAGLRGDSLETKVRGDLKKILDGQMLLGDRVTAIEEGRIAPGGR
                     TITDAAEGDLPSAMPGDIPPFPPSPSGRELESADGSLPPPPMPSVPPAPPAPPVERQVG
                     SIGTATAALTADAGDKGATGVKKKTRTIYLPPGFMKARLLTGIDALASRDATSNPEPLI
                     ARVQAPAVLPNDVKANLAGCFVIGNATGSLAKERVEVQLVSLSCVDFDERSVVDQPIKG
                     FFVDTDGKKGLSGRVVTRAGAALARSFIAGTISGMSQSVENTFGDTSVSALGTVRSLDA
                     GDAAKTGIAGGLSKSSDKLTDFYLDLARQAGPIVEVGAAKDVVVVIQEGVTLEIKPTAG
                     SKF"
     gene            19608..20243
                     /locus_tag="NUH86_RS19130"
                     /old_locus_tag="NUH86_19135"
     CDS             19608..20243
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009823920.1"
                     /locus_tag="NUH86_RS19130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_19135"
                     /product="TraV family lipoprotein"
                     /protein_id="WP_267252896.1"
                     /transl_table=11
                     /translation="MPLLSFPSALALRRAGAPLLMLAALPACTAIGSVMSPYPEKFSCK
                     NSDHGQCIHPERAYEDAVAGAASRSDPRVTNDRKMLKGSAVAASPGSTGRARGKAATPY
                     LGYRDSVYRELQGLVEAPVTPMLRPGRTIRTLILPYADRERPDRLYMPRYVYSILDKPQ
                     WVVGDYLVSPVNPTSRVPVLEQVKAKPAPMQTSDLPAPPQEQPREQGQ"
     misc_feature    complement(21554..21568)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     misc_feature    22180..22195
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     misc_feature    22300..22314
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 ttctattgac gagaaccgcg ctgactttcc gaggctgaaa tgggggtggg gcacttcggt
       61 agcggcgcct gaggaaatcg atggtgaggc caagccgttc gttcaactct ggtttgcagg
      121 caaccactcc gacattgggg gcagctaccc cgaagctgag tcacggcttt ccgatatcgc
      181 cctgcagtgg atgaccgaag aggctaggtc ggtgccattt ccgcttctcc tcaacgatcg
      241 gcgactccag ctatacccgt cacctgctgg cgtgcagcat gatgagatcg caggcatggc
      301 ggatacgata agcggcagga cgccagcctt tttgcgatgg ctgaccaagg gctggacctg
      361 gccggtcagg caacgagatc cagcggataa cgcgaccctc cacccttcgg ttgctcagcg
      421 cttcgctatg gaaaccgtgc cgagccaagg cgcggatgaa ccctatcgcc ccgaagcgct
      481 tcgaaatcac gagcttttca agcacctata ttcctgaggt cagtaagcgt gtggatgttg
      541 acgcggatgt tccggagagg atcacaatga agctcatcgg agtgattgtt ccgttcttaa
      601 tgatgctgat gagcgccacc tccgcatttg cccagccgga agtaagccca agcgagcggg
      661 ttcgacgtaa tgtcgtcgtg cgggtcgagc ccaatgccgc ttcgcagccg atcggcgcgc
      721 tgtctccagg cgacagtgtt tcggtggtcg gtgacgcgcc cggctggcat caagtccggc
      781 ttagcgatgg ccggatcggc ttcgttagta aggcctggac cattatcaga agtgggccgg
      841 agccgctgat cgacaccgcc gcgcttaaac tgcatgtcat cgatgtaggc actggtctag
      901 ccgtgttcgt ggagggccca tcattcacga tcctttatga cggcgggagt caggatgatc
      961 tggcggacgg tcctgacaat cgcatcctga attatatcca agcggtccgt cccggccttc
     1021 agacgatcga tcatctgatc cttagtcatc cgcacaagga tcatctggaa ctgctgccag
     1081 acatattcga ccgctttatg atacacaatg tgtgggactc aggagccgtc aacagaacgc
     1141 gtggctattg cagattcctg aagaaagtcg cagccgaacc gggagttcaa taccataatg
     1201 cgattgccac tggggggacg catcgcgtcg tgttcactgg caaaacctgt tcgggggaag
     1261 ttgtcttgcc gcaggcggcg atgatgacag catcacctgt tgcgcttggt ccgggtggga
     1321 ccatgtcgat cttgtaccgc gatgcctcga agcatcatga tcccaacgag aatagcgtcg
     1381 ttattcgcct ggattatgcg gggcggcgga ttcttatcgc cggcgatgcc gaaggcggag
     1441 cacgtaaggc gccgtcgcag ccggccgacg ccaacagtgt cgaaggaaag ttgattgcct
     1501 gctgctcagc agatttgcgt tcagacgtgc tcgtcgttgg gcatcacggc agtatgacgt
     1561 cgtcacgcca ggaattcctc gacaaggttc aggcatcgac tttcatcata tcttcgggac
     1621 cacaccccta cagcaaggtc gtccttcccg atgtggcaat tgaggatgag cttcgggcac
     1681 ggggcgcgct ttttcaaaca gaccttgctg atgacgattg cccagccagc gaagccaaga
     1741 tcggacccga taatgatgag agtccgggtg gttgcgacaa cgtcatcgtg actgtcagct
     1801 caactggtca ggttgcaacc ggctatttca gggaagcgga ctaagcatcg caaacttgcg
     1861 ctgatcgtcg cttgcgtttg taaattgggg cagctgtcct actttcgctc gtcgcacgtc
     1921 tcgtccccgg agcggatgtc tttaggatgt gatctcattg cggaccgtcc ggacccaggg
     1981 attgaaattt tgactctgaa cggccgggat gggtcgaaat ccccggatgt cgttgaatca
     2041 tctgcagatt agcgaagcgc ggcgcccacg gcgccgcgct ctactcgttc acgccttccc
     2101 agctacggct tgcttcaatt cgccaccgtc cgtgacaggc gcagtgcctg ctttcacggt
     2161 cggtgccgac gatttcggct ttgccgctgg cttggccgcc ttcggtgagc tcggagcttt
     2221 cccggtcctc tttggcttga tcgtttcagc ctcgacccca agggaaactg cttgatcttt
     2281 cctgccagct ttgggcgcgg gggcgggggc gggcttgtcg tccgttggcg tagcaataga
     2341 caaacgcttt cgcgctgttt gcttgtccgc agatggttcc ttttttccgg gcttggccga
     2401 ggcagtctct ggagcagcta tcttcgtcgt ttttgatgct gtcttggccc tgtccgcctt
     2461 accctttttt atgccgacat cggctgcttc ggcggcgacc actgtggtgg gcggagctgg
     2521 attgatcttc gaagccgcat ccttcggctg agcgtcctcc ttgccgttct ttgtaatctt
     2581 cgtgggcttt ctacccagac ccagcttttc ggcgacggct cgccgggcat cggaataggc
     2641 tggggcgacc ataggatagg acttgggtag attaaaccga tcgcgatact gatccggcgt
     2701 caaaccatgc tgtgccagat gtcgcttcaa tgtcttgtag ggctttccgt cgatcaggct
     2761 cagaatgaaa tcgcgcgacg cagtgcttct gcggatcgat acggcgggta cgtaaccttg
     2821 cgcttccggc tcgacctgga tcgcgaccgg gtttgtggcc aatgccgcac gtgtcgactt
     2881 gatcaggtca gccagaccgt cggcaggaac cgtattgttg gagacgaagg cgctcagtag
     2941 ctggacggtg agcgtcgtga attcattggg tgtttcatct gccatttatg cgaatccatg
     3001 gtgtggaggg agggaatgga ttactgcgtg accaagaata atttgtaaat gccaggacca
     3061 gactagatcg acttgatgca gaatgttgcg catccaaaac cgaggaacac caattgagta
     3121 cagccggtct gctgatacgc cccatccgag catgtaaaac ttcccctcac ttcgtcttga
     3181 aatcgtcctg tagaccatgc atcatccttt tgccggacgg agaatgctga cagccttccg
     3241 gtaggatttc cctgtcaggc atcaatacgt ccgtcgtgcg tgtcggacgg tcagaacaga
     3301 tgcggcagca tcgttcgaga cacacctagc caattcaccc ccgagttttc ggggctgtga
     3361 tgctgtcggt cgcatggcca ggtgttttgt gtcccgtccc attcgtgctt ccgtcctgga
     3421 tgaaggctat ggcgaagaag tcccccaatg cgtcgacgag cgctccatgg acgtcgtctt
     3481 gctggcggac gaagagatcg acacacctct attagcccag acctaccgca cccaggcgcc
     3541 gggtctgctc cgttacttca agcgtcagac ccgaaacagc gatgacgctt gcgatctgat
     3601 gcaggaggct ttcgtgaggc tcaccgccca tatgcgaaag acccccctct cccatccggc
     3661 atcctacctg cagaaaattg cgcgcaatct tctcgttgat cgcatccgcc tttccaagcg
     3721 cgcggaagcc gccttcggga aacagacatc agaagatgtc gaaatcgcag tggagccgga
     3781 tcaggggctt gcgatcgaag gagtcgacac cctgcgtctc taccgacagg ccgtggccgc
     3841 ccttccccaa aagacgcggc aggtctttat catgcagcgt gccaaaggca tgacctacaa
     3901 gcagatatcc gaggaacttg gcatttctat cccgactgtc caatatcatt tcggtcgcgc
     3961 gcttgcgcgg atcgcgcagg cactggatgg tgaatgatga tggataggcc ttcagatttc
     4021 ttgcgcgacg aggcggcagc atggttcgcc gccatgcgcg gtccggctgc agcggaccgg
     4081 aagatggagt ttgacgcctg gatggccgcc agcccatcgc atcgggcagc ctatgcgagg
     4141 attagcgaaa tatataatct cggaaagtgc ctggaattcg gtcacgaacc tgccatcccg
     4201 gcccatcggc gccaacgacg gcagctgtcc gttctggctg ccgccctgtg tctcggcatc
     4261 atatcgctcg ccgcttttgt ctggaaacct ctccaccctg ggccatcaag cgatgcctcg
     4321 cgctcgatgg cagtggcagc aaatgcgtcg aacccgatgc agaccgccat tggcgaaatc
     4381 cgcaggatca aactggccga tgggtccacc ctcacgctcg acaccgacag cctcgttcga
     4441 gccgaattca cggattcagc caggactctc catctcgagc gcgggcaggc ccgcttcgac
     4501 gtcgcgcacg aggcccggcc cttcacagtc atggcaggcg tcctgtcggt cacagctcat
     4561 ggcacagtct tcgatgtcag tgcgcgttcc aacgggcgct ctgctgtgca tctgctgcgc
     4621 ggttccgtcg aggtcaccca aagagccggc gttgaaggtc gacgaatatt gacgacgaaa
     4681 atgcttgccc cggggcaagc ggccgaaacc ggatccgcag ggctcaacct tctgaagcaa
     4741 tttcccacaa atcccgcagg gaccgactgg ccttcgctgc tgcgccagtt cgacaagatt
     4801 gaactgggcg aactgatcca ggaagcgaac cgctattcgc gcgtgaagat ccggccgcct
     4861 gcgcccgaag ttgcggcaat gcgggcgtcg ggcacgttca ggatcaacga tccccagcgt
     4921 ctggccagca atcttgcact tcttctcgat ctgcgcgccc ggaatgagcc agacggcacg
     4981 atcagtatca cggcccaata aatttttcgc gagccggcag ccctctcata aatcggtaaa
     5041 ttcgagcgtg gtccccgtca tgcgccgcaa tcggcgcgcg acagacaaag ggggacatag
     5101 tgcgacagat attccatgga ttggcttcct cggtgttcag catcgcagcg atcacaaccg
     5161 ccagctatgc cccgatcgcg atctcgcaga gtgatcaaag gattgaactg catatcgcag
     5221 agcaggatct ggccgcctcg ctccaggcgc tgggcgccgc gacggggcgt gagatcctgt
     5281 tccggcccga agccgtagcg ggcagaaccg cgccggcaat cgagggccat tttacagcca
     5341 cgcaggcgct caccattctt ctcaggtcga gcgatctgcg ctttcgcgag aatggcagga
     5401 gcctggtgat ccgggggcga tcggaagcgt cggcggcgct aagtgacggc gctgacgcgg
     5461 cgaacacgct cttcgtcacc ggctcccgca taagaggcgc ggatgcgcca ggatcgaacg
     5521 tcatccgtct cgatcgaaag gctatcggcg aaagcggcta tgcgtctgcg cagcagatcc
     5581 tccagtcgat cccccaagcc tatggcggcg gcgccaacga agcgacgagc ggcgccaccg
     5641 gcgcgagcgg cgcaaatctc aacgcgtcct atggatcctc gatcaatctg cgcggtcttg
     5701 gcccctcctc cacgctggtg ctcctcaacg gcaatcgtcc agccctgggc ggctccggcg
     5761 gcgtctttgc agacatatcg atgctgcccg tcagcgcgat cgagcggatc gaggtccttc
     5821 ccgatggcgc atccgcgatc tacggatccg atgcggtcgc cggcgtcgtc aacctcatca
     5881 cacgccgaaa attcgagggg ctcgaaaccg gccttcgcta tggcacggct gacggagatt
     5941 tttcggagat ccaggccagc caggtcgccg gcaccaaatg gagttcgggt cgcgccgtgc
     6001 ttgcgatcga atattatcgt cgcggtagcc ttgcggcaga tgatcgtgat ttcgcaacac
     6061 aggacctgcg ccgttggggc ggtagcgact atcgcgttca gttcgccaac cccggaaaca
     6121 tcgtggctgg cggcaagacc tacgcgattc cctccggcca ggacggaagt tcgcttgttg
     6181 catcggacct ggtcgcaggg tcgctcaacc gacaggacgg atgggagcag gccgaccttc
     6241 tcccacgcca gacgcgctat tccgtctatg gtcgggtcga acaggatgtg accgacggca
     6301 tcacgctgga cattgagggt ctgtacgccc ggcggtcctt ctccaaacgc gtgaaccccg
     6361 caggctatca atcctccatc accgtcacac ccgacaatcc ctattatatc gatcctatcg
     6421 ggacaggccg cgcgatcagc gtccgctatg atttcaccga cgagcttggc ccgcgtaccg
     6481 atcagggcaa ggtcgaggcc ctggggttca acggcggcgg tacgatcgct cttggcggct
     6541 gggcaatcga tatccgtggc acctatggga aacagatcga gaatttcggg acgatcaatc
     6601 ttcccaatac cgctcgactg gccgtcgctg cggcgagcag caatccctcg attgccgtca
     6661 atctccttgg ggacggcaag gtcaacagtg ccacggtgct cgactatatt cgcggatcga
     6721 cacactcgcg cttcgcgtcg acaatatggt cgggcgcggt gcgtggtgac ggtccgctgg
     6781 tcaacctccc cggtggccag gcgcgccttg ccttgggcgc cgagcatcgc gatgaacgct
     6841 tcaaatcgcg gtccgtttcg gaccagagcc ggctcgagcc atatgttttc accggcacgc
     6901 agggcgcgcg caatatcgaa gccgtttatg gcgaaatctt cgtgccggtc atcggcgcag
     6961 cgaacgccct gcccgcattc caatcgctga gcctgtccgc agcagtcagg cacgagcggt
     7021 ataacgactt cggctccacg acgaacccga agttcgggct atcctggaaa cctgtgtccg
     7081 gtctggagct taaaggcagc ttcggcacct ctttccgggc gccggggttc gtggaactgc
     7141 ggcagacacc ggattcggac gtctatttca tctatcccgt cagcgatccg cagtcaccca
     7201 ctggcaccag caacgtgatg tactatcgcg gcaacaagac cggcatgaag ccggaaaagg
     7261 cgcgcacatt caccctgggc tttgttttgg agccagcact gcttcctggc ctgcgccttt
     7321 cgtcgagcta ttttgatatc cgctataaag atcagatcgt cgatctgaca tccgccctgc
     7381 tgcagatgct gaacaatcgg gcaacctatg ccgcgctgat caacgacaat ccctcgctgg
     7441 agatgctgca ggccgccatc aactcgccga atttcatcga ctatcttggc ctgcaagccg
     7501 ccgatgtcga tgttttcatc gatgcccgaa cgcaaaatct cgcggttgtc cggcagaaag
     7561 gcctggactt cgatgcccaa tatcaatttc cagcggggag cggcacagcc cggcttggca
     7621 tcgatggcac ctatctcttc cgcttcacac gtgccgcgag cgcatcggcg ccagccatcg
     7681 acatattgaa cagcatcaac aatccggtcg acctgcgtct gcgcgcgcat gcgggatgga
     7741 cctctggccc cctctctgcg ctcaccagcc ttaactatgt gcgcggctat accaacagca
     7801 tcgtcagtcc ggccgagcat gtggatgcgt ggaccaccat cgacgcgcag ctcagctacc
     7861 gcttcgagaa caagacaggc gtgctgcagg accttgctgt tgcgctcagt gcgacgaatc
     7921 tgttcgacaa ggatccgccc tacgcggcct tctctttcaa cgggatcacg gcggttggct
     7981 atgatccgca aaacgccaat ccgctgggcc gggttgtttc gcttcagctg accaaggcgt
     8041 ggtgagatgc gccttccata ctgcctcgtc gctgtcctgt ttgcggcagt cggcgccctg
     8101 ccgtccgctg ccgccgcgct ctgctccccc ccgccgacac gcgcggagca gagcgccaca
     8161 aatggcgcca atgtcagccc cgaggatctg ctcggcctct gggactttgg cgatggtgga
     8221 tccagccctc tgaatgcctc ccatatcgcg ctgtccccca acaagaagca actggcggtg
     8281 cagatgcgcc gtgctgacgc agcaaccaat cgctactgca tggcgcttgt gatcatcgac
     8341 cgaagcgggc agagcgcgcc tatcatagcc gatcagggcg gagacttcat aaaggcgcaa
     8401 ttttccaacc gccgtctggc gggattcccg atcggcctgc ccatgccgct gacgccgcgc
     8461 tggtcgccgg acggacatca tatcgcctat gtgcggcgcg accaggggca gacccggctt
     8521 tggatcgcca atgcggatgg cagcggggca gaagcggcaa cgtccgggga cctgccgatt
     8581 tccgatctga gatggtcggc agatgggcgg catgtgcttc tggcagccga cacgaaccgc
     8641 ctggaagctg aacgtcgcat cgaggaagaa gggctttccg gctttcacta tgattatcga
     8701 atatggcagg cggcccgcgc ccttcccttt ccgcccggcc cgtacccgcc catctattat
     8761 caggtcgatc gcgagacgaa acagctgatg agccttccgg cagacgccgc cagcaaggct
     8821 ttcggatcgc gcggcgaagg cattccggca aacgccaggc ttggcacgtt cagtgatgat
     8881 ggaaatgccg cagcgtgggt cgagcgtgag cagccggatc agctgcgctc accctcaagg
     8941 cttcacgcag tcgtcgatgg cgttcccatc gcatgtcaaa gcgaagcgtg tgcaggcgaa
     9001 ttgctcggca tctggtggac cgatcggcgc gaaatcctgt tcctgcgaac ggaaggtcca
     9061 gccgaccgga gccaccttgc actttacaaa tggcacccac ggcgtggacg acccaccctc
     9121 ctcctgcgga cggaggatct cattctcggc tgccaggcag gcaagggcga actgttttgc
     9181 ggctatgagc gcagcctcga gccgcgccgg gtcgtcgcca tttcggcgcg ggacggcgcc
     9241 gtctccaccg tctatgagcc taaccccgat ttcgcgcggc atcgcttcgg cgcggtgcaa
     9301 cgcctctatt ggaaattcca gggcggtgaa gcctttggcg atcttgtcct gccgcccgac
     9361 tatcggaacg acaggaagct tccccttatc gtcgtccaat atacgagccg cggctttctg
     9421 cggggcggaa ccggcgatga atatcccata ttgccgctgg ccgcggcagg ctttgccgtg
     9481 ctgagttttc agaggccgac ggattatgcc aatcgcatcc ctgccgcgaa tattgcggag
     9541 ttcagccaaa acaatgtcac tggctgggcg gatcggcgtc atgtcctgaa cgctcttgaa
     9601 gccggtgtct cacaactgat tgaccgcgga ctggtagacc cggcgcgcat tggcatctct
     9661 ggcctcagcg acggggcgtc gacggtccag ttcgccctgg tcaattccag tatgttccgc
     9721 gccgcagccg tcagctcctg ctgcgaagac ccgagcaatt acgacagcgc cggcgaggaa
     9781 tattatcgcg atctcgtcag ttggggctac ccgccccgag gcacggacgg ccgcaaattc
     9841 tggcagcgct attcgcttct gcaaaatgcc gacaagattg cggcgcccat tctcatgcag
     9901 ctttcagacg acgagtttcg tcttgcgctc cccgcctatc acgcccttga ggctgcggga
     9961 aaaaccgtgg acatgtatgt ttttcccgac gagcatcata tcaaatggca gccggcgcat
    10021 cgcctcgcga tctaccggcg atcgattgcc tggtttcgcg gatggctgac ccctcaagga
    10081 gaccccgcgt caccttccgc cggcgaacgg ccctgaccca catttccgta tcccacagca
    10141 ccatcagccg gttgatgccg ccacttccgc tttcctggaa tcggaaaaac tcctcatcca
    10201 cggcgtctac atcgatgatt ttttccgtag caagccagcc atcgtgcaga tgcgccttca
    10261 tttctccgct gcgctccttg aagatatcgc ggatcacagc atcaaagccg cccttcgacc
    10321 ggcgacccga gatcatcggg ggcaatctgt cggcgagcaa tcggcgaacc ggggcacggt
    10381 tgcgcccgcc ctcaaaccat tgccaggtcg gtatctgaag cgccgtttcg accaccggct
    10441 tcgacacgag cgggaaccga agggcgtcgt ggcgaggcgc gctgtaggca tccaggtgat
    10501 tatggatgcc gatcatgtgc ttgagatgat cgcatttgcc tctcggcgcg cagcccagat
    10561 cgatcccccg gtgataggcc cggcgcgaca gcgaccgccg cgtatcacgg gacaggaatg
    10621 agccatccct tttccaggaa agccgatgcg gcaggctcat cctgcgcaat gcccgccaga
    10681 taatctccgc gctggtggta tcatgggcgc gcgcaagatc atggacaacc gccggactgt
    10741 tcaacatcgt tttccaactg cccagacaat cgatcaacgg tgcgctggag ggaaggtagc
    10801 aaaaggtgcc gtcgccgccg cccccgctca tgatcatgtc gcagccaagc tcgtccatcg
    10861 ccctatccgc cgcctgatcg aacagctgag taaaaagccg ggcgctcggc cacgcgagat
    10921 gcgcggcagc cgattcatgg aggcggatgt gatcagcgga caggaccgat ccgcgccact
    10981 gccggcccaa atgggcgcaa actgccctgg caaaatcgct ctcatcttct cgcgcgtcag
    11041 gcccgacata ggtgaccgcc gtaaagtcga tcgccatgtc cgccaggagc atggcgagga
    11101 gggaggaatc caatccgccg gacaattcca gcattacgcg actggcgccg ttcgtttgcg
    11161 cgcgcacggc gaccctcagc accctctcca gccgctccgc aatctcttca tgcggaagcg
    11221 cgcggcccac ctccaggtcc acgagcggtt gccagacata gcgaacctcc tcattttgat
    11281 cactggcggt gcatcccggt gtcagttcgc ggacggattt caacgccgtg cggtcctgcc
    11341 gaagatctcg ataggcaagc gcccggataa ttccgtcccg gcaaatctcg aaatcctgcc
    11401 cggtgacgag gcgcaaaaga tcgacgctcg acgcggcgaa gaacgcgctg ccgacgcggc
    11461 acatgtagca ggcctgccca gccgatggat ccctgtagaa gcgcactgtc tgcgcatcga
    11521 ccgtgacagc gacaaactgc ccccaatggc gcgacgccac cgtttcgagg gtatcagcgg
    11581 aatgcgccgc cctgtcgagg ctctcccggc tcaggcggcc gccagctgca tcaaaggctt
    11641 cgccgattat gacaaggcgc cggtccgacg aaatctcaac gcgtcccctc aggaaaagcc
    11701 tgtagttcgc gtcgatcgac gtttcggaaa agtcgtcagt cagggacaga tcggcaaggg
    11761 cccgccgagc gatgccgata gccggtcccg ctgatggaca gaggatgaaa tcgctcatgc
    11821 ccggcaccgc atgatcggcg taaatcgacg cacatggtcg atttcgtcgt tcaggagcca
    11881 cccatcgcgc tcgagccagc aatgcgcggc aaagggatcg agactgacgc caaagaccag
    11941 ttccgtcatg gaatctccaa caaaatggta gagcgcaacg ctgtctagga ggcagacgcg
    12001 ggatagcgga atggctggcc ggcaagcggt aaagcgcccg acacggtcca tcacgacctg
    12061 ctgctcccga accggcatct gtcctgctcg tttccgcatc ggctcgaggg ttctcgcaag
    12121 cgatcccgtt gctatgcgca ggcgcgtcgt ggcaagaaac caggcgatct gcagatactc
    12181 ggcacgattg gcggacgaca cgcaaatctc ggcgcggctc ttcaggggtt tcgccgcgca
    12241 tgcctccaga cgtcgatttc ccgcctgttc gcgggacaca tatccctttg ccatcaggtc
    12301 atcgaatgtt tcgtctgaat gcctgctttc agcgcccgct tcccattgga tcagcgcctc
    12361 acccgatgca ccgtggatca ggaaatagcg ggtcgtcctc atatcgagtg cgacgacgcg
    12421 cccgtcgacc agacaatggt gaaaatgagg cgttgcgtag agcatcgttt cgtagatcgg
    12481 cgcggccaga gccgcgccga tcccttcgga ttattcgtcg gccatgccgt tcaggcggta
    12541 gccgacgccg tccgacggtt cgcccgcgat cgcgcccttg gtttcaaagg cggcgttgcc
    12601 cagatcgacg aagtcgtcgg agaggtcttc gatacgttcc atgttcatct ccatcatgca
    12661 ggccgcagtc atttgcggca ggcatgatga taagtagctc gccccttata cccgatctta
    12721 taagttctca tttcaccggc ttataagcgc catattggag ataaccccgc accggcggca
    12781 atcaaagccg ctgaacatca gcttctaccg gcagtgtcgg aggatggcgg gactgcgcta
    12841 attctgtgag cgattgccga agcgcgtcgt atccgtctcc tgtgataggc ccagatggca
    12901 tcacgtaatg cggcatcctg accggatctg gtcaggttcc agatcgcaag cagttcttcc
    12961 tcgacattct tgacgacgga cggctcatgg agtcgcgcga ccgaaagcaa ctcgcccgcg
    13021 gcaaggaccg catggagatg tacctgattt ccaggcctgc tgccaatccg gccgaacagc
    13081 gcggcggttg catcgcgaat atccttggga tgatgtggac cactgcgctc caggattgcg
    13141 ataggccctg gctcccccgc aacgggacta tttgccttca gggcatgcct gaccagatag
    13201 ccatgccaga cataaaggtc gcgcagcacc tgcgcatcga gttgcgggat ggtgaaccct
    13261 cccccgacat tgaggcccaa tagtctctcg cccaccagcc gatgcgcgcc atcgcgtacg
    13321 ggcgatatgc tcacgccata gtgctcagct gcattctgta cgatcaactg ggatcccgga
    13381 gggaagacgc catcgagtat atcggccttg agccggcgat agatgcgctc tgccgtcagg
    13441 ggttcaggtg ccatcaagac ctcccgtcag gacggttcgc catcatcacc cggcccgaag
    13501 aaggaggatc tgcgccgggt gacggcggcc tgcgaatgct catagacgag cgcgatgcag
    13561 cgatcttcca gttcggagag gtcctcctcc accagatatt cctcgggaat cgacattctt
    13621 cgctccatga gaagaagcgg gatcatgatg tgggtggtcg agagaccaag ccgatgggca
    13681 catgcaagat gctcatcaag cttcgacttg ggattgcccg cctcaatttc ccgcaaccat
    13741 cgaacactga ccccggccgc gcgtgcaagc tgaggctgcg tgatccggtc acgtcggcgg
    13801 cgctcttcga tccgtttccc ggaaatctcc tttatcctgg agagaaccag cacgttatcc
    13861 ttggtctgaa gtcttcgagt cggcatgcgc aggcacccct gacactggct cgaagcttcc
    13921 aatggcactt acccgatcgc cgaaatctat gcatttgacg cacgcggtca aaaacaatca
    13981 ttctcatttt gagatgaatt cgacgatcca acctgatgtt ggcgccggcg tcctgtgccc
    14041 gcagcattta tgatcgcgcc cgctcgcgcg cgagacgagc gacccagctg gtcaattcgc
    14101 ggttctccga ggcgccaaga acacccagcc cggcgatgta aatccgaccg atctggggcg
    14161 catgcatcaa gcctgtctgc gataatctct ccctgatcgc ccgcgccgac cggccgatag
    14221 caggcgaacc gcccacgaaa tgctcgcatt tgccgaaata gatatccagg cgattgtcga
    14281 gcatctcggc cgccacctca tcgcaatccc gctgctccaa aagatcgatc gcagcctgga
    14341 gcgttgctcc atagggtaac agatcctgcg ccaggatgca cagacgcagg tggacagaga
    14401 gatagagttc caagccgcgt tccgaaaggg tcagccgata ggcgcgtgac cttttaccgt
    14461 tcatcctttg cactttcctc actgaaaaat gacgggcgga gcctgacgcg attcgtccag
    14521 caaggcggag tgtatccgcg atggtcgacg cttcgcccgt tacaaacgat ccatgatgcg
    14581 gcacgcaaat gcccaagcgg cacttcactg ccgcctggcg gcacgtcagt gccctgcacc
    14641 ggcacgtcat tgccctggcc attgcagggc gggggcggtc tcgacatcga tggtttcaac
    14701 aaccggtgac ggcgagctta cccgaatgac cgaagcttcc cgccagcacc cttcccgaaa
    14761 ccgggccgcc gcttcagccg cccagatgcg aggagacatg ccccatgggc agaggcattc
    14821 ctatcggcgc ccccacgctc gtcattctca tggcggcaac tatgcccgca atggcggcca
    14881 aagggcaagc catggtgaag gcgcgagttc ccactgactg ggtccaacct ctcgccgttc
    14941 ggcagcaggg cggcgagttc atcatcgagg cggtaaccct gggccaaatt ccgcccgctc
    15001 ccgcaatgac tgtaccgctt gggcgctcga tccgcttcga tccggcgctc cttgcccggc
    15061 cattccacga caggaaagga aatcatgatg tcatgccacg cacggatcgc taagacactg
    15121 gcgattgcgc tgatcgcagg cgctgctggg gtcgtgaacg cggcacctgc agagcccgcg
    15181 acggatccgg tcgctctcga cgctgtagcg gcaaaggcgc aggcaagcct ccgccaaagc
    15241 ttcaccaacc tccagttcga ggatttcggc cctgcgcccg tcaaaggccc cgtgtttcag
    15301 gcgagcgccg gcggccgcat cctctattat gcgcctgaca gcgagcacct tctgttcgcc
    15361 accatctacg acagaaacgg cgtcaacctg accgccctcg cacaggatgc cagcgcgcgg
    15421 aaaaaactgg gcgcgctcgg tcccaatcaa gcactcacca ttggcccgcc gggcgcgccg
    15481 accgtcatcg agttcaccga tcccgattgc ccctattgcc gcgccctcga tcgtttctgg
    15541 gcggcaaagg cagccgaagg gaagccagtg cgacggcaaa tctatttcgt gagcggtatc
    15601 cacccgcaag ccgcgtccaa ggccgagcat atcctctgct cgaaggacca ggctggcgcc
    15661 ttccgcgcca cctatgccgg agacgcgcca aagcccctca cgacctgcaa ggagggcgcg
    15721 gcgcttgttg ccaggaatgc cgaggcggtc aaagccatgg gcatatcggg aacccccacc
    15781 ctcattcttg atggccgcgt catttccggc ttccagcagg ccgagatcga ggcctggctc
    15841 gaggaaaagc aggcgcccaa aaagccgccc agctgatttc ctccaaattt ggcgggctca
    15901 tggcggcggg cgcaagcgcc gactccctga gcaacagatg ccggtgagag gggcccgtta
    15961 ccaaggagcc acccatccct tcgctggccg tcaacgaaca gccgtgtcgg tgccggcagg
    16021 cattttcatg gggaggctcc ttattgcctg gagaaagctc atgctcaaac ttgcctcact
    16081 gcctgccccc tcccggaacc ggatgcgccg cctctctttt gcgtcggccg atgccgtggg
    16141 aaccctgctc atcgcgatga ccctggcatc ggccgcccac gccttccagg cgccggccgc
    16201 cggcgacctt ggctacgata tttacgacat cgtggtgaac cagggggtga aggggccgct
    16261 cggcttcgtg ggcggcgtcg ccgccttcct gttcggggtc agccgcctct tttccaacat
    16321 catgatcggc atcccgacga tcgtcgctgc cgtctgcctc attcgggcgg attccatcct
    16381 ccagaccttc ggcatgatgg tctgagatcc gcctgaaaca gagactggcg cggatctcag
    16441 gttccgggtc cgcgccggac acggggaacg aatggtcgct cttcgtaaca atcacgtctg
    16501 gtccaggcgt gatgaagcaa gggagaagga cgtggacgag agacttcccc aattcctgca
    16561 caagccggtc cagatcctct ggttcgacgc gcaggagttc atcctcgtgg tgtccaccat
    16621 cttcgtcgcc gtcatcgtcg gcggatatgt gggctggtcg ctcctcggcg ttcttctcct
    16681 cttcattccc tggaagcgga ccaagccgcg cggcttcatg ccgcatctcg cctggcgctg
    16741 ggggctgctc aagctccccc gctaccccgg tccgacccag acccgctttt gcgagtgagc
    16801 tatcccatgt tcggcagatc atccgcccgc gagcccagcg accccttgcg ggataagccg
    16861 gcgagcttcg gcatccatcg ctatctccag gggtcgtcca acctgttcga ggagaaccgc
    16921 ctcctaaaat tctcggttct cggcctgttc ggcatcaccg ccgtcctggg gattgccctt
    16981 tactcgacga gccagaacca gcgcacgatc gtcgtgccct ttggggcagg cggcgatctc
    17041 tatgtgacgg gcggcaagcc ctcgcccgct tacctgcgca ccatgacgcg caatatcgtc
    17101 gcgctttcgg gcacctattc cgcgctctcg gccgaccggc agtttgagga attgctcagc
    17161 atcgtccacc ccactgccta taatggcatc cgcgacagtc tgaacgcgat cctcgacgaa
    17221 ctggccaata atccgacgct ctcgatcgcg acctatatcc ggcccgacca gcccgtcacc
    17281 tggacggatc gccagatcct ggtgccagtg gaaaaggtgc gcgtcatcgg cggcgtcatc
    17341 cgcaaattcc gcggcaatct gcgcatccgc tacacgatcg atgccggtcg cttctggctc
    17401 ctgtctcttt ccgaggaaaa tttcgatgcc gaacttcggt aagcgccttg gcgcgcctgc
    17461 agcgctcatc accgcctgtc ttccggtccc gacattcgcg caggccatca tggccctgcc
    17521 cgaccagatc agtagcatcc gcctctccaa ccgcgacatc aaccatctca tctgccaggg
    17581 cggcgagatc gaggatgtca aattctccgc cgaaaaggcg atcgcggtcg agaaggcggg
    17641 tgctgacgcc tgggtcaagt tcctggtcaa ggaaagcgac gatgcgggcc aggtgacgcg
    17701 cagctttgtc accacgcctt cggaattctt cgtgacctgt aacggcgcga tctatccgct
    17761 ttatgccgaa cccaccgaca ttcccgccca gaccgtgacc ctcgcacccg gtgccagcca
    17821 gcgcgcccgc gccaatggcg agctgctggg gccgcttgtc gaggaggagc gcgcggtctc
    17881 gatcaccctc tcaatgctgc aggaccgggt gccggccagc tttaccgaga tcgccgtttc
    17941 gccaaggccg cttgcgctca gcgccgcgcc cgccttgcgc atcaccgagc gccgccgcgt
    18001 cgcgatcgag ggcacggggc tgtcggcgtc ggaatattgg atcgaggcga gcaccgacaa
    18061 cgagattgac gagcgcatat ttctcgatgc gtcgctcggc gcgcgcatct tcagcgtcac
    18121 cctcgatcgc ctgtccctga aggccggcga gaccgcgcgt ctcattctgc tgcgtcgggg
    18181 agagacgctg tgagcggccc tggcgacaag ggcggcgaga agccaatggg tgcgcaaccg
    18241 acgggctcga ggcccgatgc accgacccag cggccccacg ccggcataaa gggctattcc
    18301 cgcccgccaa agaggaggga cggcgccagc ggcgaaccgg atgatcgcgc cgccacggag
    18361 gtgcgcggtc cggcactgct cgacctcaag gcccgctggg cgttgctgag cgctcgccag
    18421 cagctgcgcg cccggcaggc cggtgtgggc gtcgtcatcg cgatgttcgg ctacggcctc
    18481 tacacagcct cgaccggatc gaaggacgag gcgccggcgg caccggtggc atcgcgcctc
    18541 gacatgggtg cgggcctgcg cggcgacagc ctcgagacca aggtgcgcgg cgacctcaag
    18601 aaaattctcg atggccagat gctgctcggc gaccgggtga ccgcgatcga ggaaggcagg
    18661 atcgcccctg gcgggcgaac catcacggac gcggcagagg gcgatctccc cagcgccatg
    18721 cctggcgaca tcccgccctt cccgcccagc cccagcggac gcgaacttga gagcgctgac
    18781 ggcagcctac cgccgcctcc tatgccgtcc gtgccgcctg cgccgcccgc cccgccagtg
    18841 gagcggcagg tcggctcgat cgggaccgcg accgccgcac tcaccgccga cgcgggcgac
    18901 aaaggggcaa caggcgttaa aaaaaagacc cggacgatct atttgccgcc tggtttcatg
    18961 aaggcgcggt tgctgaccgg gatcgacgcg ctcgcgagcc gggacgcgac ctcgaacccg
    19021 gaaccgctga tcgcccgcgt ccaggcgccc gccgtgctgc caaatgacgt caaggcgaac
    19081 cttgctggct gctttgtcat cggcaatgcg acaggcagcc tcgccaagga gcgggtcgag
    19141 gtccagctcg tctccctctc ctgcgtcgac tttgacgaac gctcggtggt cgatcaaccg
    19201 atcaagggct tcttcgtcga taccgacggg aagaaggggc tgtcgggccg ggtcgtcacc
    19261 cgcgccggcg ccgcgctcgc ccgcagtttc attgccggca cgatctcggg aatgagccag
    19321 agcgtcgaaa acacgttcgg ggacacgtcg gtctccgcgc tcggcaccgt ccggtcgctc
    19381 gatgcgggcg acgcggccaa gaccggcatt gccggcggcc tctccaaatc ctccgacaag
    19441 ctgaccgact tctatctcga tctcgcccgt caggccggtc ccatcgtcga ggtgggcgcc
    19501 gccaaggatg tcgtcgtggt gatccaggag ggcgtcaccc tcgaaatcaa gccgactgcg
    19561 ggaagcaaat tctgatgcgc ccgcgcctca aacaaggaga cacgcccatg ccgctcctct
    19621 ctttcccgtc agcgttagcc ctgcgccgcg ccggagcccc gctgctgatg ctcgccgccc
    19681 tgcccgcctg caccgccatc ggctcggtca tgtcgcccta tcctgaaaag ttcagctgca
    19741 agaatagcga ccatggccag tgcatccacc cagagcgcgc ctatgaggat gcggtcgccg
    19801 gcgccgcctc ccggtccgat cccagggtca cgaacgacag gaagatgctg aaaggcagcg
    19861 ccgtcgccgc ctcgcccgga tcgacgggac gcgccagggg caaggccgcc acgccttatc
    19921 ttggctatcg tgacagcgtc tatcgcgagc ttcaggggct ggtcgaagcg ccagtgacgc
    19981 cgatgctgcg gcccggacgc acgatccgca cgctcatcct tccttatgcc gaccgtgaac
    20041 ggcccgaccg gctctacatg ccgcgctacg tctattcgat cctcgacaag ccccaatggg
    20101 tggtcggcga ctatctggtg agccccgtca atccgacgag ccgtgtgcca gtcctcgagc
    20161 aggtgaaggc gaagcccgcg ccgatgcaga cgagcgacct tcccgctccc ccgcaggaac
    20221 agccgcgaga acaggggcaa tgaaggcgcc cggcacccgt catgtcggcg gcatgacctt
    20281 cgagcggctg cgccagagcg tctcgcgcga cgcctattcc gactttctgc cgatggtcgc
    20341 ctgggtcgcg gaggaggaag ccttcctctg catcgacgat ggctggggcc aggcctggga
    20401 actcgtgccc agtgcctatc tcttcgccca tgtccatcag gcgctgctcg gcctcctcaa
    20461 catccacttc gcgccgggca cggtggttca gctccactgc ttcgccgacc cgctgatcga
    20521 cggcgcgctc gacgcgttcc tcgatctgaa atcccggccc gatccgttga tccaggcttc
    20581 ggcgcgccgg acccgcgact atctgcgcga cgggacgcag gggctcgatg cgctgcacgg
    20641 cattccgctg cgcaatttcc ggctgctgct ttcgatcaag acgcgcaaac cgcttggggc
    20701 cgacctgcgg cgacagatcg aggagcagct ttccaagctt ggcatcaccc gcctcgcgcc
    20761 cgaggcgctc gtcaccttct atcgccgcat cttcaacggc gtgttctctg ctgcaccggg
    20821 ggttttcgcc caaggcagcg aggacatgcc cgcgcgcccg gtgcgcaagc agctgatcga
    20881 tgccggcccc gatctcgtct tcgatggccc cgagctgttc ctcggcgatc aggtcgcacg
    20941 ctgcctgacg cccaagtcgc cagcccggcg cgtcaccgcc gaacgctgca accggctgct
    21001 gggcgggatg cgcggtgcct cggaggacag cgaccagatt ggcggtccct tcctctacac
    21061 gctcaacatc ctcttcgatc attcgagctt cgaaatccat aagcgtgccc agatcctctc
    21121 cgcgcaaaag gccgccggca gtttcgcggt cgaggtcggc aagcagatcg aggagatcgg
    21181 ctgggtgctc gacgaagcgg ggaacagccg ctttgtctcg gtcatcccgg tcatctgggt
    21241 cttcggccgc gacagcgcgc aggcccgcga gatggccgcg cgcgccaagc gcctctggga
    21301 aagcgagccg ctgccctgga tgatgcagga ggagagctat ctcaatccgg tcctgctacc
    21361 aatggcgctc cccttcggct tctatcccga ccgacggacg gtgcggatgc tggagcgcga
    21421 ccttcccatg cccgccaagg cggcagcgct gctcgcgccg gtgcagaccg actttcgcgg
    21481 cggggggcgc cccgccctcc tctatgccgg ccgcaagggc cagctcatca cgctcgatct
    21541 cttcgacccg cgcatcaaca attataattt catcgtttcg gccgagagcg gcgcgggcaa
    21601 gagcttcctc ctcaataacc tctgccagca atattatgcc caaggcgcgc tcatccgcat
    21661 catcgatatc ggcggcagct atgccaagct ctgcacattg tgctcgggcc gctacatcga
    21721 cattggcgag gagcatctca tcctcaaccc cttcgacatg ggcttcgcgc tcgacggcga
    21781 cgatcgccag tcggccatct ccatggcggt cgccatcgtc gcggaaatgg ccaatgccgc
    21841 gacccgcaag ggcgtcagca cgtccgaatg gaacctgctc aagtccgcag tccaatggac
    21901 aatcgacagc ggacgggccg aagccgggat cgatgcggtc cgtgactggc ttggcgccta
    21961 tcccgcctat gccacaagcg atctcgacaa ggtcgagcat ctgatccccg ccgcgcgcga
    22021 acttgccttc aacctgcgcg attttgccag ttcgggcgct tatggccatt atttcaacgg
    22081 cccctcgacc ttcgacattt ccgccgatga atttgtcgtg ctcgagcttg agcgcctcaa
    22141 agccatgccc gatctcttca atgtgatcgt gatggtggtg gtgaatgcgg tcacgcagga
    22201 actctatctc tccgcccgcg atcggccccg ctttgtcctg tgcgatgagg ccgctcagtt
    22261 catgacccgc accgacgggc aggatctttc ccgcctcgcc gaggtattcg gccagggcta
    22321 ccggcgcgcg cgtaaatatc aggggagttt cggggtcgtc ctccagtcga tgaacgatct
    22381 gctgctcttt ggcggcacgg gacaggtgat cctcgaaaat gccgccaccc gcttcctgct
    22441 ccaggggtcg acctacgatc gggcc
//
