LOCUS       NZ_CP102664            24259 bp    DNA     circular CON 07-JAN-2024
DEFINITION  Sphingobium sp. JS3065 chromosome 1, complete sequence.
ACCESSION   NZ_CP102664
VERSION     NZ_CP102664.1
KEYWORDS    RefSeq.
SOURCE      Sphingobium sp. JS3065
  ORGANISM  Sphingobium sp. JS3065
            Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
            Sphingomonadaceae; Sphingobium.
REFERENCE   1  (bases 1 to 3555142)
  AUTHORS   Li,T., Xu,J., Xu,Z.-J., Xu,Y., Spain,J.C. and Zhou,N.-Y.
  TITLE     Molecular mechanism and evolution of 1-nitronaphthalene catabolism
            in Sphingobium sp. strain JS3065
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3555142)
  AUTHORS   Li,T., Xu,J., Xu,Z.-J., Xu,Y., Spain,J.C. and Zhou,N.-Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2022) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 800 Dong-Chuan Road, Shanghai,
            Shanghai 200240, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. v0.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio RS
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/07/2024 05:42:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,942
            CDSs (total)                      :: 4,873
            Genes (coding)                    :: 4,751
            CDSs (with protein)               :: 4,751
            Genes (RNA)                       :: 69
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 122
            CDSs (without protein)            :: 122
            Pseudo Genes (ambiguous residues) :: 0 of 122
            Pseudo Genes (frameshifted)       :: 40 of 122
            Pseudo Genes (incomplete)         :: 96 of 122
            Pseudo Genes (internal stop)      :: 12 of 122
            Pseudo Genes (multiple problems)  :: 23 of 122
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:10:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2636108
            Orig. end                         :: 2660367
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102664.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24259
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24259
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24259
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14259](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14259)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            354..1139
                     /gene="lptB"
                     /locus_tag="NUH86_RS12900"
                     /old_locus_tag="NUH86_12900"
     CDS             354..1139
                     /EC_number="7.5.2.5"
                     /GO_component="GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lptB"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007709503.1"
                     /locus_tag="NUH86_RS12900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12900"
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="WP_013847841.1"
                     /transl_table=11
                     /translation="MDDVMMQDRTAPASPLPPQEVGEGLSVISIAKSYDKRVVLADVSL
                     TVGKGEVVGLLGPNGAGKTTCFYSVMGLVRPDHGRIVLDGQDITGLPMYRRSILGLGYL
                     PQETSIFRGLTVAQNIGAVLELAEPDKAARQARLEQLLEEFGLTRLRDSSAMALSGGER
                     RRCEIARALAANPSIVLLDEPFAGIDPLSIADIRGLVKQLKTRGIGVLITDHNVRETLE
                     IVDRACIIYDGKMLFAGSPTELVANADVRRLYLGENFSL"
     gene            1188..2699
                     /gene="rpoN"
                     /locus_tag="NUH86_RS12905"
                     /old_locus_tag="NUH86_12905"
     CDS             1188..2699
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpoN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020818998.1"
                     /locus_tag="NUH86_RS12905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12905"
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="WP_267249873.1"
                     /transl_table=11
                     /translation="MALAPRLDLRQSQSLVMTPQLQQAIKLLALSNLEIEAFVAGELEK
                     NPLLEAGGADDFAPPADGVDRAAEQHDLRAETGDADRLIGQGLGAADSPLDVDYGAETF
                     IDDGPGDRVASAAIGSGGMDILSGSGEAPDFDSFANPEQGLQEHLMDQARSALSGMDLT
                     IATQLIGQIDEAGYLEANLLETAHGMGVALYRVEQVLAVIQGFDPTGVGARSLSECLAL
                     QAREADRYDPCMAKLLANLDLLAKGALPQLRRICGVDEEDMADMIRELRGYDPKPGLRF
                     STESAAPVTPDLFVRPTREGWSIEVNSATLPRVLINRTYYVELASGPQDRTSKAWLADC
                     LASANWLVKALDQRQKTIVKVASEIVRQQEDFFRKGVEHLKPLTLKTVADAIQMHESTV
                     SRVTSNKYLSCPRGMYELKYFFTSGVAAASGDGAVSAEAVKSHIKALIAAETPDAILSD
                     DTLVDLLRAKGMDIARRTVAKYREAMGIGSSVQRRRQKALRGQAA"
     gene            2990..3841
                     /locus_tag="NUH86_RS12910"
                     /old_locus_tag="NUH86_12910"
     CDS             2990..3841
                     /EC_number="2.6.1.21"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (46-274). E-value: 1.2e-33.
                     Score: 108.7. Matches aSDomain:
                     nrpspksdomains_NUH86_RS12910_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020818997.1"
                     /locus_tag="NUH86_RS12910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12910"
                     /product="D-amino-acid transaminase"
                     /protein_id="WP_267249874.1"
                     /transl_table=11
                     /translation="MSIAYLNGRFLPLAEAQVSVLDRGFLFADGIYEVAAVIDGKLVDS
                     ASHLARLERSTGEIGIALPLSLAEIEAAQKELVARNTLTEGLVYLQITRGADATRDFLP
                     SPDIQPTLVMFVQARPFLDVPAARDGIAVATMPDLRWARRDIKSVGLLAQAMAKRAAAQ
                     AGAQEAWMVEDGFVTEGASSTAFIVTEEGIVTRPYSQAVLAGCTGAALTALAEESGIAI
                     VRRPFTVAEALAAKEAFIASASTLCQSVVRIDGQAIGDGTPGPVAMRLRALYIDFARRT
                     AV"
     aSDomain        3128..3811
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NUH86_RS12910_Aminotran_4.1"
                     /evalue="1.20E-33"
                     /label="NUH86_RS12910_Aminotran_4.1"
                     /locus_tag="NUH86_RS12910"
                     /protein_end="274"
                     /protein_start="46"
                     /score="108.7"
                     /tool="antismash"
                     /translation="SHLARLERSTGEIGIALPLSLAEIEAAQKELVARNTLTEGLVYLQ
                     ITRGADATRDFLPSPDIQPTLVMFVQARPFLDVPAARDGIAVATMPDLRWARRDIKSVG
                     LLAQAMAKRAAAQAGAQEAWMVEDGFVTEGASSTAFIVTEEGIVTRPYSQAVLAGCTGA
                     ALTALAEESGIAIVRRPFTVAEALAAKEAFIASASTLCQSVVRIDGQAIGDGTPGPVAM
                     RLRALY"
     gene            4098..5102
                     /locus_tag="NUH86_RS12915"
                     /old_locus_tag="NUH86_12915"
     CDS             4098..5102
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013847844.1"
                     /locus_tag="NUH86_RS12915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12915"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_267249875.1"
                     /transl_table=11
                     /translation="MGLDHDEIGFGASLDQPFGARDDRPGLLILADDVYLDDAAMLSRA
                     AGLRLLGTVPLDQASTRLDVQIGCDIILCFCPTPDAMIERLLVQIETLALQNDMPVILV
                     ADLETVDLAYACLRSERTQLLCRPGHTDLAAALLAAARQTGSGAFHEANRDNEGLRLQQ
                     LSDEVSRLARTLEALTLRPRHATPSFELGPRISDEPSDYIGMPSLEPIGSADKSGDAAV
                     VDAAQVRDLLRARRLRDDFLPADLFADPAWDMLLDLLAARLEHERVSVSSLCIASAVPP
                     TTALRWIRTLTEKGFVDRQADPHDGRRVFIALADHTAEALSRWFTASRRFLCA"
     tRNA            5188..5263
                     /anticodon=(pos:2641329..2641331,aa:Val,seq:tac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="NUH86_RS12920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="NUH86_12920"
                     /product="tRNA-Val"
     gene            5188..5263
                     /locus_tag="NUH86_RS12920"
                     /old_locus_tag="NUH86_12920"
     gene            5352..5525
                     /locus_tag="NUH86_RS12925"
                     /old_locus_tag="NUH86_12925"
     CDS             5352..5525
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NUH86_RS12925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NUH86_12925"
                     /product="hypothetical protein"
                     /protein_id="WP_267249876.1"
                     /transl_table=11
                     /translation="MSLTLLLAGAIAPFLLILSPVSLATARDCLDWDAPAKAVDVAVEK
                     PCPKKKPPLLLM"
     gene            5582..5809
                     /locus_tag="NUH86_RS12930"
                     /old_locus_tag="NUH86_12930"
     CDS             5582..5809
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013847861.1"
                     /locus_tag="NUH86_RS12930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12930"
                     /product="zinc-finger domain-containing protein"
                     /protein_id="WP_013847861.1"
                     /transl_table=11
                     /translation="MIQPPEIIRVTKSRVSCDGSGEIPAALGHPRVFLEIDEHGYVDCG
                     YCDRRFVLAGGVADTPEIAGLPDISSGASL"
     misc_feature    5852..5861
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.31"
                     /tool="antismash"
     gene            5898..7340
                     /gene="tldD"
                     /locus_tag="NUH86_RS12935"
                     /old_locus_tag="NUH86_12935"
     CDS             5898..7340
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="tldD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013038833.1"
                     /locus_tag="NUH86_RS12935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12935"
                     /product="metalloprotease TldD"
                     /protein_id="WP_267249877.1"
                     /transl_table=11
                     /translation="MTDAAPQFTDARGLLYRPGLLDPDGARRLTAEALKSCDDGELYLQ
                     YRASESFGFDDGRLKTADYSTDAGFGLRGVSGEMTGFAHANDISEAAIRRAAETLTLLD
                     PAKGQPAPPPQHTNRHLYTDVNPLEIVPFAEKVTLCAAIDAAARARDPRVAQVSVSLAG
                     SWSVVEIVRADGFTATDIRPLVRLNISVILEENGRRETGVFGIGGRYLYDEVMDPAIWN
                     RAIDEALAQARVNLRSVAAPAGEMTVLLGPGWPGVLVHEAIGHGLEGDFNRKGTSAFSG
                     RVGQRVAASGVTVVDDGSIMSRRGSLSIDDEGTPTRENVLIEDGILKGYMQDRLNARLM
                     GVEPTGNGRRESYAHAPMPRMTNTFIKGGNDDPEELLSRMKTGIFAKSFGGGQVDIVSG
                     KFVFSCTEAYKVENGKLGDPIKGATLIGDGPTALTKVIGIGNDWALDEGIGMCGKGGQS
                     VPAGVGQPTLLMEGLTVGGTAT"
     gene            7395..7970
                     /locus_tag="NUH86_RS12940"
                     /old_locus_tag="NUH86_12940"
     CDS             7395..7970
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004209786.1"
                     /locus_tag="NUH86_RS12940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12940"
                     /product="DUF924 family protein"
                     /protein_id="WP_267252133.1"
                     /transl_table=11
                     /translation="MNMLTDSHDAVTADWAAALLDFWFNQTGEQGWWSHDPAFDRTCQA
                     RFRTLWEEKRLLPAEAFLDRADDALAAVLLFDQLPRNMFRGSATAFSTDPLARDVARGA
                     IAHGYDIQIGGAGRLFFYIPFQHSEAMEDQKLSLSLFAGAGDAQSLAFAREHHAVIERF
                     GRFPHRNAVLGRPTLPEEAEAAARGAGW"
     misc_feature    complement(7407..7421)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    complement(7973..7989)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.69"
                     /tool="antismash"
     misc_feature    complement(8002..8018)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.99"
                     /tool="antismash"
     misc_feature    8073..8086
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     gene            8123..8461
                     /locus_tag="NUH86_RS12945"
                     /old_locus_tag="NUH86_12945"
     CDS             8123..8461
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014074444.1"
                     /locus_tag="NUH86_RS12945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12945"
                     /product="P-II family nitrogen regulator"
                     /protein_id="WP_267249878.1"
                     /transl_table=11
                     /translation="MKLVMAIIKPFKLDDVREALSSLGIAGMTVSEVKGFGRQKGQTEI
                     YRGAEYSTNMVPKIKIEVVCDDDLAPRVVEAIQAAANSGAIGDGKIFVLDVEQAVRIRT
                     GETGETAL"
     gene            8475..9899
                     /locus_tag="NUH86_RS12950"
                     /old_locus_tag="NUH86_12950"
     CDS             8475..9899
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008519 - ammonium transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013038831.1"
                     /locus_tag="NUH86_RS12950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12950"
                     /product="ammonium transporter"
                     /protein_id="WP_267249879.1"
                     /transl_table=11
                     /translation="MTFSKKLCGAMGAVGLSLLAAAPALAAPIKGPDAAAMAAMVNKGD
                     VAWMLVSAALVLMMSVPGLALFYGGLVRTKNMLSILMQVFMIVSVAGLVWCCWGYSIAF
                     TSGGSNPFFGGLSKAFLMGVDGTTYGATFSNNVYLPEFVFVVFQMTFAMITPALIVGAF
                     AERVKFSSLIVFVVLWLTVIYFPMAHMVWYWAGPDFLVDAPTDYGLLWGWGALDFAGGT
                     VVHINAGIAGLVGALMIGKRVGFPKEPMPPHSLTMTMIGASLLWVGWFGFNAGSNLEAN
                     AVTGVAFINTMVATCAAAVSWSLVEQVHHGKASLLGAVTGAVAGLVAITPAAGFAAPMT
                     SIALGFIVSPICYIFVAFVKGKVGYDDSLDVFGVHCIGGIVGAIATGIVAAPSLGGQGV
                     FDYTVFPAAFHPEAYSIPTQVWIQVKAVVFTLLFSGIGSAILYFIIDKTLGLRPSKEAE
                     MEGLDLSSHGERAYNY"
     gene            complement(10001..10921)
                     /locus_tag="NUH86_RS12955"
                     /old_locus_tag="NUH86_12955"
     CDS             complement(10001..10921)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019515260.1"
                     /locus_tag="NUH86_RS12955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12955"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_267252134.1"
                     /sec_met_domain="phytoene_synt (E-value: 6.8e-40, bitscore:
                     134.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.4e-67,
                     bitscore: 225.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQARESIARGSKSFALASKLFDRQTRERAWLLYAWCRKCDDIAD
                     GQDHGGTMRGVADGQARLSSIRVLTAAALRGEPTGDPAFDGFGLVMRECAIPERYAHDL
                     IEGFALDAREWRPRSAADMLRYCYHVAGTVGCMMAILMGVDPDDEATLDRACDLGLAFQ
                     LANIARDISEDEAADRCYLPEEWLVEMDIPPGEHMKPWVRPRLAILARRLADMAAAYEE
                     SARHGTGALPPRAAWAVLAAAGIYGDIAREVARRGEHAWDHRVATAKSDKIRWVVSAGL
                     QIPGRASRWPAGTPRPNRLWTRPRD"
     gene            complement(11016..11597)
                     /locus_tag="NUH86_RS12960"
                     /old_locus_tag="NUH86_12960"
     CDS             complement(11016..11597)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lysine_decarbox"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020820268.1"
                     /locus_tag="NUH86_RS12960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12960"
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="WP_267249880.1"
                     /sec_met_domain="Lysine_decarbox (E-value: 3.9e-45,
                     bitscore: 150.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRLAVYCGSATPADPAYVESARHVGRTLAQRGIGVVYGGGRLGL
                     MGAVADAALEAGGEVIGIIPEALVGAEVAHRGCTELHVVQTMHQRKQLFTDLSDGFVTL
                     PGGVGTMDELWEAISWAQLGYHQKPVGLLNVAGFYDQLIAFNQHMVEAGFIRAQHANIL
                     IHANAIEALLDRMAAYQPHETIFAMKADRL"
     gene            complement(11604..13085)
                     /locus_tag="NUH86_RS12965"
                     /old_locus_tag="NUH86_12965"
     CDS             complement(11604..13085)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013847868.1"
                     /locus_tag="NUH86_RS12965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12965"
                     /product="phytoene desaturase"
                     /protein_id="WP_267249881.1"
                     /transl_table=11
                     /translation="MNRKAIVIGAGFGGLALAIRLQSAGIDTTLVEARDRPGGRAYMWE
                     KDGFVFDAGPTVITDPDCLGELWRLSGHDMAEDVTLIPVSPFYRLNWGDGTNFDYSNDE
                     TALRAEIAKLNPEDVAGYESFLDYADGVYQEGYRKLGSVAFLDFASMVRAAPALMKHQA
                     WRSVYSVVSSHVKNEKLRQALSFHTLLVGGNPMQTSSIYALIHKLEKDGGVWFAKGGTN
                     RLVQAMATHFERLGGTLRLADPVTRIETYGDRAVAVRTASGWRGEADAVASNADLMHSY
                     RDLIGHHPRGQKQAEKLSRKRWSPSLFVLHFGIKGSWPGIPHHMILFGPRYRGLLTDIY
                     DYGVLPQDFSLYLHHPTVTDPGMAPDGHSTFYALAPVPHLGKLPIDWERFGPVYAERIL
                     DEIQHRLIPDIRSRIVTQFHYAPPDFRQDLSAHLGSAFSLAPLLTQSAWFRAHNRDDVI
                     PNLYLVGAGTHPGAGIPGVVGSAKATAALMLEDLV"
     gene            complement(13096..14259)
                     /gene="crtY"
                     /locus_tag="NUH86_RS12970"
                     /old_locus_tag="NUH86_12970"
     CDS             complement(13096..14259)
                     /EC_number="5.5.1.19"
                     /GO_function="GO:0045436 - lycopene beta cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtY"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007686868.1"
                     /locus_tag="NUH86_RS12970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12970"
                     /product="lycopene beta-cyclase CrtY"
                     /protein_id="WP_267249882.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 1.4e-111,
                     bitscore: 370.9, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATMTDFDLAIVGGGLAGSLTALAFAARHPDAALLLLESGDTLGG
                     NHIWSFFDSDVDAGDRWLVDPLIAHRWAEGYEVRFPGHSRRLAMPYNSITSTRLDAHVR
                     QVLGDAVLTGAQAAELTPTAVTLSDGRIIRARAVLDARGGGDLSALRCGWQKFVGQTLR
                     LRAPHGLTRPVIMDATVDQLDGYRFVYLLPWDDRTLFVEDTYYSDTPDLDIPALEARIA
                     AYAQARGWQVEGVVHSESGVLPVVHGGDFDRFWLDADAVARTGVRAAMFQPMTGYSLPD
                     AVRFALRLADEWPMEGRLLAHVTREWAAIHWRQGRYYRLLGRMLFGAARPAQRWRIFER
                     FYRLGPALIGRFYAGRSTLGDRIRILCGRPPVPIRDAMRTLLSPPAR"
     gene            14335..14607
                     /locus_tag="NUH86_RS12975"
                     /old_locus_tag="NUH86_12975"
     CDS             14335..14607
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017183776.1"
                     /locus_tag="NUH86_RS12975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12975"
                     /product="metal/formaldehyde-sensitive transcriptional
                     repressor"
                     /protein_id="WP_267249883.1"
                     /transl_table=11
                     /translation="MHIVADRDKLLARVRRIAGQIGAVERQLSGDAGCSETLQLVASVR
                     GAVGSLMEELIEQHMREHVARPDISDETRQAAAEEMLALIRRYGK"
     gene            14604..15590
                     /gene="dmeF"
                     /locus_tag="NUH86_RS12980"
                     /old_locus_tag="NUH86_12980"
     CDS             14604..15590
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="dmeF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007686870.1"
                     /locus_tag="NUH86_RS12980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12980"
                     /product="CDF family Co(II)/Ni(II) efflux transporter DmeF"
                     /protein_id="WP_267249884.1"
                     /transl_table=11
                     /translation="MSMHDDHDHGGHPHPGHDHAHALPAVGGDEENHYFDHIYLTHGHD
                     ENARKTMWVVWLTAATMVVEIVFGWLTGSMALLADGFHMATHAGALAVAAAAYGYARRH
                     ARNPRYTFGTGKVGDLSGFASALILAFTALFIAVESVMRLFEPVKVAFGEATLVAVTGL
                     VINLISAVLLRHDHSHDHSRDDGHGHDPKQGHADNNLRAAYVHVLTDALTSVLAIVALL
                     AGRFIGWWWLDPAVGLLGAVVIARWAWGLMRDTAAILLDTAEPALTARIKGLAEAEGAT
                     IRDLHVWRIGPHAHAAIVSLAPGADVAAVRRQVRALPRMEHVTVECG"
     misc_feature    complement(15614..15627)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
     misc_feature    complement(15670..15679)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.73"
                     /tool="antismash"
     gene            15798..15953
                     /locus_tag="NUH86_RS12985"
                     /old_locus_tag="NUH86_12985"
     CDS             15798..15953
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NUH86_RS12985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NUH86_12985"
                     /product="hypothetical protein"
                     /protein_id="WP_267249885.1"
                     /transl_table=11
                     /translation="MASQIWQDSHGSMTGQNWRDVAKGSDAHRQMINAALMAFGSAPSE
                     LHMEAS"
     gene            complement(16176..17360)
                     /locus_tag="NUH86_RS12990"
                     /old_locus_tag="NUH86_12990"
     CDS             complement(16176..17360)
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013847872.1"
                     /locus_tag="NUH86_RS12990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12990"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_267249886.1"
                     /transl_table=11
                     /translation="MASKAENYDAIVLGAGGAGLMCAAMAGQRGRRVLVIDHADQAGKK
                     ILISGGGRCNFTNIHTAPDRYLSVNPHFAKSALGRYTPQDFLALVERHGIAWHEKTLGQ
                     LFCDRSARQIVAMLLAECEAGGVTIRLDHAISSVTHADGRYSVTHGGRTATAPALVIAT
                     GGPAIPKIGATGIAYDLARQFGLKVVEPRPALVPLTLGGEDLLFRSLSGVSTEVVARHG
                     KTAFREAALLTHRGLSGPAILQISSYWRHGEAIALDFLPDRPQGWLIDAKRSRPRATLT
                     QCLRGHLPDRLADALAERLALPGDLGNMPDRKLQDAERRLSAWSFTPNGTEGFAKAEVA
                     IGGISTAGLSSQTMEARHLPGLYAIGEAVDVTGWLGGYNFQWAWASGWVAAQFL"
     gene            complement(17360..17788)
                     /locus_tag="NUH86_RS12995"
                     /old_locus_tag="NUH86_12995"
     CDS             complement(17360..17788)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007686872.1"
                     /locus_tag="NUH86_RS12995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_12995"
                     /product="TIGR01244 family sulfur transferase"
                     /protein_id="WP_267249887.1"
                     /transl_table=11
                     /translation="MFRQLTKNLYVAPQISVDQVAEAKALGVTMIVNNRPDDEEPGQTN
                     GAEIEAAAKAAGIAYAAVPVAHGGFAPWQLDGMAAALEQAGEGKILAYCRSGTRSTLLW
                     ALTRARAGDHPAALTEQAASAGYDVAPVRQIMDALAAG"
     gene            complement(17863..19635)
                     /gene="recQ"
                     /locus_tag="NUH86_RS13000"
                     /old_locus_tag="NUH86_13000"
     CDS             complement(17863..19635)
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recQ"
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007683151.1"
                     /locus_tag="NUH86_RS13000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_13000"
                     /product="DNA helicase RecQ"
                     /protein_id="WP_267249888.1"
                     /transl_table=11
                     /translation="MRPDIPTLLHDIFGFPAFRGVQEQVVSRIMAGQPTLAIMPTGAGK
                     SLCYQLPAVALDGCCVVVSPLIALMHDQLRAAQAVGIRAASLTSVDTDWRETQDRLRNG
                     DLDLLYVAPERASGEGFRNLLRAAKIALFAIDEAHCVSEWGHDFRPDYRLLRPLLDEFP
                     DVPRLALTATADHHTRDDILVQLGIPREGLIIAGFDRPNIRYAVHPRDGLPRQLSDLIA
                     GQTGPGIVYAPTRAATEKLAETLGKTGRPTRAYHAGLAPQMRAANQAAFIASEDMVMVA
                     TIAFGMGIDKPDVRFVAHAALPKSIEGYYQESGRAGRDGEPAEAHLFWGADDFARARQR
                     IGELDPLRQQGERARITALGGLVETGTCRRAILLRHFGENPPPGCGNCDNCLNPPPSID
                     ATQTARKFLSAVYRTGQSFGVGHIEQVLTGAVSDKIRERGHDKISVYGIVDGEETALLR
                     PVSRALLVRDALQTNEHGGLEFGPNARPILRGEEEVSLILPPRKERRRKSARSGSAENP
                     VGDPLFDALRACRRELAQEAGVPPYVIFHDSTLREMAEQRPTSLAELGNISGVGQRKLD
                     AYGDAFLAAIRPYL"
     gene            complement(19692..20006)
                     /locus_tag="NUH86_RS13005"
                     /old_locus_tag="NUH86_13005"
     CDS             complement(19692..20006)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013847875.1"
                     /locus_tag="NUH86_RS13005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_13005"
                     /product="hypothetical protein"
                     /protein_id="WP_267249889.1"
                     /transl_table=11
                     /translation="MSVRRKWIYGALAAALLPLALFAWNWSALRAHAQVGAGFGARVAC
                     SCRYVEGRSMESCKGDKEPGMWAVSLKDMPESQSVNAAVPLLVSRTARYRKGWGCLLEP
                     "
     gene            20044..21165
                     /locus_tag="NUH86_RS13010"
                     /old_locus_tag="NUH86_13010"
     CDS             20044..21165
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007683145.1"
                     /locus_tag="NUH86_RS13010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_13010"
                     /product="serine hydrolase"
                     /protein_id="WP_267249890.1"
                     /transl_table=11
                     /translation="MRVERNSVKRLGAIGGILAMLAVAGLWTVRAAGPEPVVHIAGDSD
                     VDAAALRAAIDPLFEDQAGETRALIVMHDGEIVAERYAPGYGPQTRLPSWSTAKSVTAV
                     LIGLMVSDGRLALDSPAPVAAWGQPGDPRGRITLRQLLAMTSGLDHVEDAEPLAEADTV
                     RMLFTDGAQDMGAFAEAKPLAHAPGSVFSYSTGSTIILTDLMARMLTNSSDPDVRRRAM
                     QMFIDGRLKIPARLDSLTVEYDAAGTMIGGSFMHMTARDYARFGELLRNHGRGVAGHQI
                     VPEKWIDHMRAPSPRNAAYGAHLWLNRESEESALMPGRAPRSLFGCVGHGGQYILVSPS
                     QRLTVVRLGMSPDKEQRGVVKDGLAKLVGLYAR"
     gene            complement(21259..22047)
                     /locus_tag="NUH86_RS13015"
                     /old_locus_tag="NUH86_13015"
     CDS             complement(21259..22047)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004209761.1"
                     /locus_tag="NUH86_RS13015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_13015"
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="WP_267249891.1"
                     /transl_table=11
                     /translation="MTSLPFIQVDAFADAPFTGNPAAVMPLGQWLDDATLQAIAAENNL
                     SETAFTVPTPDDPDADYALRWFTPEVEVKLCGHATLASGHALMGGRTAVRFRTTHAGIL
                     TVSRDRDGYALSLPAWTTEPSPLPDLAAAMGGDVLETRWRDGGYAIFAYPDDAAIRALQ
                     PDFATLKKAGSILLIATAPGEDSDMVSRVFAPGAGIDEDPVTGSAHCLLTPYWAGRLDK
                     AKLTAYQASHRGGRLLCRLSGDRVILTGACRTVIEGNFLL"
     gene            complement(22377..23465)
                     /gene="aroC"
                     /locus_tag="NUH86_RS13020"
                     /old_locus_tag="NUH86_13020"
     CDS             complement(22377..23465)
                     /EC_number="4.2.3.5"
                     /GO_function="GO:0004107 - chorismate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="aroC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020820260.1"
                     /locus_tag="NUH86_RS13020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_13020"
                     /product="chorismate synthase"
                     /protein_id="WP_267249892.1"
                     /transl_table=11
                     /translation="MSFNTFGRVFRFSTWGESHGPAIGAMVDGCPPGLPLSEADIQPFL
                     DKRKPGTSKFTTQRREPDEVRILSGVFEGRTTGTPISLMIENTDQRSKDYSEVAKAYRP
                     GHADYAYDAKYGFRDYRGGGRSSARETASRVAAGAVARLVIPDVDIFAYVSEIGGDPID
                     YARFDAGEIDNNPFFCPDPEAAKRWEKLVDDARKDGSSLGAVVECIASGVPAGWGAPLY
                     AKLDSELAAAMMSINAVKGVEIGDGFAAARLRGEQNADPMRPSRDGGKDGAPVFLANHA
                     GGIAGGISTGQPVKVRIAFKPTSSILIPVETVTREGAASDIVTKGRHDPCVGIRGVPVV
                     EAMMALVLADQKLLHRAQCGEG"
     misc_feature    complement(23867..23876)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
ORIGIN
        1 cgccgccagt tccgcctttt ccgccgcgag gggcgcggcc gccctgccgc gaaacagcca
       61 gcccaggcca aggcccacgg ccagggcgac gatgacgaaa atggcggaca gactgtccat
      121 gaaaacccct ttatggaacg aaaggtgaac atagcggcgt gacggcatcg gcgcaagcct
      181 catcccgccc gacggccgga accggcccgc gcgacggcat tgaaagcggc tctgcctgcc
      241 ccatctagca ttttcccctt gccccggcgg ctatcccatg cacaaagctt gccaattgtc
      301 gcggccgggg caggatttac cggcgatcaa ccatgcggca gcaaggatga atgatggacg
      361 acgtgatgat gcaggaccgg acagcaccgg catcgcccct tcccccgcag gaagtgggag
      421 agggcctgtc cgtcatctcc atcgccaaaa gctatgacaa gcgcgtcgtg ctggccgatg
      481 tgtcgctgac cgtcggcaag ggcgaggtgg tcggcctgct aggccccaat ggcgcgggca
      541 agacgacctg tttctattcg gtgatggggc tggtgcggcc cgaccatggc cgcatcgtgc
      601 tggacgggca ggatatcacc ggcctgccca tgtatcgccg gtcgatattg gggctgggct
      661 atctgccgca ggaaacctcc atttttcgcg ggctgacggt ggcgcagaat atcggcgcgg
      721 tgctggaact ggcggagccg gacaaggcgg cgcggcaggc gcggctggaa cagttgctgg
      781 aggaattcgg cctgacccgg ctgcgcgatt cgtcggccat ggcgctgtcg ggcggcgagc
      841 ggcgccgttg cgaaatcgcc cgcgccctgg cggccaatcc gtcgatcgtg ctgctggacg
      901 agcctttcgc gggcatcgat ccgctgtcca tcgccgatat tcgaggcctg gtgaagcagt
      961 tgaagacccg cggcatcggc gtgctgatca ctgaccataa tgtccgcgag acgctggaga
     1021 tcgtggatcg cgcctgcatc atctacgacg gcaagatgct gttcgcgggc agcccgaccg
     1081 agcttgtcgc caatgccgat gtgcggcggc tctatctggg cgagaatttc tcgctctgac
     1141 atgatggagg agcagcccct tcctgacagc ggcgagggga agagctgatg gcgctcgcac
     1201 cccgtctcga cctgcggcag agccagtcgc tcgtcatgac gccgcagctt cagcaggcga
     1261 tcaagctgct ggcgctgtcc aatctggaga tcgaggcgtt cgtcgcgggc gagctggaga
     1321 aaaacccgct gctggaggct ggcggggcgg atgatttcgc gccgcccgcc gacggtgtgg
     1381 accgggccgc ggaacagcat gacctgcgcg cggagacggg cgatgccgac cggttgatcg
     1441 gccaggggct gggcgctgcg gattcgccgc tggatgtcga ttatggcgcg gaaaccttca
     1501 tcgacgatgg gccgggcgac cgggtggcga gcgccgccat cggctccggc ggcatggaca
     1561 ttctgtccgg cagcggcgag gcgcccgatt tcgacagctt cgccaatccg gaacagggcc
     1621 ttcaggaaca tctgatggat caggcccgca gcgccctgtc gggcatggac ctgaccatag
     1681 cgacccagtt gatagggcag atagacgagg ccggttatct ggaggccaat ctgctggaaa
     1741 ccgcccatgg catgggcgtg gcgctctaca gggtcgagca ggtgctggcg gtgatccagg
     1801 gcttcgatcc caccggggtc ggggcgcggt ccctgtcgga atgcctggct ttgcaggcca
     1861 gggaggcgga ccggtacgac ccctgcatgg cgaagctgct cgccaatctg gacctgctcg
     1921 ccaagggggc gctgccgcag ttgcggcgga tctgcggcgt ggatgaggag gatatggcgg
     1981 acatgatccg cgagttgcgc ggctatgatc ccaagcccgg cctgcgcttt tccacggaga
     2041 gcgccgcgcc cgtgacgccc gacctgttcg tgcggccgac gcgggagggc tggtcgatcg
     2101 aggtcaacag cgccaccctg ccccgcgtgc tgatcaaccg gacctattat gtcgaactgg
     2161 cttcagggcc gcaggacagg acgtcgaaag cctggctggc ggattgcctg gccagcgcca
     2221 actggctggt gaaggcgctg gaccagcggc agaagaccat cgtcaaggtc gcgagcgaga
     2281 tcgtccgcca gcaggaggat tttttccgca agggcgtgga gcatctgaag ccgctgacgc
     2341 tgaagaccgt ggccgacgcg atccagatgc atgaatcgac cgtcagccgg gtgacgtcga
     2401 acaaatatct gtcctgcccg cgcggcatgt atgaactcaa atatttcttc accagcggcg
     2461 tggcggcggc cagcggcgac ggcgcggtgt cggccgaggc ggtgaagagc catatcaagg
     2521 cgctgatcgc ggcggagacg cccgacgcca tattgtccga cgacacgctg gtcgacctgc
     2581 tgcgcgccaa gggcatggac atcgcccgcc gcaccgtggc caaatatcgg gaggcgatgg
     2641 ggatcggctc ctccgtgcag cggcggcggc agaaggcgtt gcgggggcag gcggcttagg
     2701 accaatcgcc attcagccca tggcggcctg caaatggcac ttttccgtgc ttccggtgct
     2761 cacgtactta agtacgctgc gctccgggtc acgaaaaact accattttcg gctcgccctg
     2821 aactgaatgg cgattggtcc tagcggggat tctcttactt tcgtcatgct aaacttgttt
     2881 cagcatgacg gatgaggagg ggacggaaat ccgttcataa gcttgacccg accgacacaa
     2941 gcggcgacat cgggcatttc ttcaccctaa gggatttcgt cgccgcccca tgtccatcgc
     3001 ctatctgaac ggtcgttttc tgccattggc cgaagcccag gtctccgtgc tggatcgcgg
     3061 cttcctgttc gcggacggca tttacgaggt cgcggcggtg atcgacggca agctggtcga
     3121 cagcgcgtcc catctcgccc ggctggaacg gtcgaccggg gaaatcggca tcgccctacc
     3181 cctctccctt gcggagatag aggcggcgca gaaggaactg gtggcgcgca atacgctgac
     3241 ggaagggctg gtctatcttc agatcacgcg gggcgccgac gcgactcgcg atttcctgcc
     3301 ctcgcccgat atccagccga cgctggtgat gttcgtccag gccaggcctt tcctggacgt
     3361 gcctgccgcg cgcgacggca tcgcggtggc gaccatgccc gacctgcgct gggcgcggcg
     3421 cgacatcaag agcgtgggcc tgctcgccca ggccatggcc aagcgtgccg ccgcgcaagc
     3481 gggcgcgcag gaggcgtgga tggtggagga cggcttcgtc accgagggcg cgtcctccac
     3541 cgccttcatc gtgacggagg agggcatcgt cacccggccc tatagccagg cggtgctggc
     3601 gggttgcacg ggcgcggcgc tgaccgcgct ggcggaggaa agcggcatcg ccatcgtccg
     3661 ccgccccttc accgtcgcgg aggcattggc ggcgaaggaa gccttcatcg ccagcgcctc
     3721 gacgctctgc cagtcggtgg tgcggatcga tggtcaggcc atcggcgacg gcacgcccgg
     3781 tccggtcgcg atgcggctgc gcgctcttta tatcgacttt gcccggcgca cggccgtttg
     3841 agcaagaggg cgtttgagca aaagagcgcg caaaacttga tccgtttcgg atgaaagaac
     3901 ggaacgccgc cattccccat ttcggcgggg atcgagcctc cattttggtg gttcgttacg
     3961 gcgggaccgg aaaagacccg tttacaaggc ggtcgatgga cgcgatgggc ggcctttatc
     4021 tccataatgg agaatggcct ggctgcgtaa cgacggcgtt aagtttagct ggaccaaaca
     4081 ggatgggagg tttcggcgtg ggtttggatc atgatgagat cggtttcggc gcatccctgg
     4141 accagccctt cggcgcgcgg gacgaccggc cgggcctgct gatcctggcg gatgacgtct
     4201 atctggacga cgccgcgatg ctgagccggg cggcggggct tcgcctgctg ggcacggtgc
     4261 cgctggacca ggcgtcgacc cggctggacg tgcagatcgg ctgcgacatc atcctgtgct
     4321 tctgcccgac gcccgacgcg atgatcgaac ggctgctggt gcagatcgag acattggcgt
     4381 tgcagaacga catgcccgtc atcctggtgg cggacctgga gaccgtcgac ctagcctatg
     4441 cctgcctgcg cagcgagcgg acccagttgc tttgcaggcc ggggcatacg gacctggccg
     4501 ccgcccttct ggccgccgcc cgccagaccg gctccggcgc gttccatgag gccaaccggg
     4561 acaatgaagg gctgcggctc cagcaattga gcgacgaggt gagccgcctg gcccgcacgc
     4621 tggaggcgct gacgctgcgt ccccgccatg cgacgccgtc cttcgaactg gggccgcgca
     4681 tatcggacga acccagcgac tatatcggca tgccgtcgct ggagccgatc ggcagcgccg
     4741 acaagtccgg cgatgccgcc gtcgtggatg cggcgcaggt acgcgacctg ctgcgggcgc
     4801 ggcggctgcg cgacgatttc ctgcccgccg atctgttcgc ggaccccgcc tgggacatgt
     4861 tgctggacct gctggcggcg cggctggagc atgagcgcgt gtccgtgtcc agcctgtgca
     4921 tcgcgtcggc ggtgccgccg accacggcgc tgcgctggat aaggacattg acggaaaagg
     4981 gcttcgtcga ccgccaggcc gatccgcatg acgggcggcg ggtcttcatc gcgctggccg
     5041 atcatacggc agaggcgttg agccgatggt tcaccgccag ccgccgtttc ctgtgcgcgt
     5101 gacgaatatc cggtcatccc cgcttgaccg gcgtcccgat tgccgtagat aggcgcgcac
     5161 cggacgcctg cggtcaacaa aggcatcggg cgattagctc agttggtaga gcgtctcgtt
     5221 tacaccgaga atgtcggcgg ttcgagcccg tcatcgccca ccatatcccc ctttccagaa
     5281 atctgttccc gcctggaccg aagtggcgta gggtcgccgc caccgaacgc ttttgcgagg
     5341 cgcatggcat catgtctctc acgcttctcc ttgccggtgc gatagcgcct ttcctgctga
     5401 tcctgtcgcc ggtttcgctg gcgaccgccc gcgattgcct ggattgggac gccccggcca
     5461 aggcggtcga cgtcgcggtg gaaaagccct gcccgaaaaa gaagccgccg ctcctgctga
     5521 tgtaaacgcc cttcgccacg gatattgcgg cgcggcgtca gcgctgctaa tcggtgccgc
     5581 catgatccag ccgcctgaaa tcatccgagt caccaagtcc cgcgtctcct gcgacggttc
     5641 gggcgaaatt cccgccgcgc tgggccatcc gcgcgtcttc cttgagatcg atgagcatgg
     5701 ctatgtcgac tgcggctatt gcgaccgccg cttcgtgctg gccggcggcg tcgccgatac
     5761 gccggaaatc gccgggctgc cggatatttc ttcgggcgcc agcctttaat cttcatttca
     5821 tgggctgtcg ctcgtcagaa tggcgtagct tcgatttttg attgggcttg ccgcctgccg
     5881 ctcctatatc aggcggcatg accgatgccg ctccccagtt caccgatgcc cgtggcctgc
     5941 tttatcgccc cggcctgctc gatcccgacg gcgcccgccg cctgaccgcc gaggcgctga
     6001 aaagctgcga cgatggcgag ctttatctgc aatatcgggc gagcgagagt ttcggattcg
     6061 acgatgggcg tctgaagacc gccgattatt cgaccgacgc gggtttcggc ctgcgcggcg
     6121 tgtcgggcga gatgaccggc ttcgcccatg ccaacgacat cagcgaagcg gcgatccgcc
     6181 gcgccgccga gacgctgacg ctgctcgatc cggccaaggg ccagcccgcg ccgccgccgc
     6241 agcacaccaa ccgccatctc tacaccgacg tcaatccgct ggagatcgtg ccctttgccg
     6301 agaaggtgac gctgtgcgcg gccatcgacg ccgccgcccg cgcccgcgat ccgcgtgtgg
     6361 cgcaggtgtc ggtgagcctg gcgggaagct ggtcggtggt ggagatcgtg cgcgcagacg
     6421 gcttcaccgc gaccgacatc cgcccgctgg tgcggctcaa catctccgtc atcctggagg
     6481 agaatggccg tcgcgagacg ggcgtgttcg ggattggcgg gcgctatctc tacgatgagg
     6541 tgatggaccc ggcgatctgg aaccgagcca tcgacgaagc gctggcgcag gcgcgggtca
     6601 atctgcgctc cgtggccgcg cccgcgggcg agatgaccgt gctgctgggg ccgggctggc
     6661 ccggcgtgct ggtgcatgag gccattgggc acggcctgga gggcgacttc aaccgcaagg
     6721 gcaccagcgc cttttcaggc cgcgtgggtc agcgggtcgc ggcgtcgggc gtcacggtgg
     6781 tcgatgacgg atcgatcatg agccgtcgcg gctcgctctc catcgatgac gagggcacgc
     6841 cgacgaggga aaatgtgctg atcgaggacg gcatcctcaa gggctatatg caggaccggc
     6901 tgaacgcccg gctgatgggc gtggagccga ccgggaacgg ccgccgcgaa agctatgccc
     6961 atgcgccgat gccgcgcatg accaacacct tcatcaaggg cgggaatgac gatccggaag
     7021 agcttctgtc ccgcatgaag acgggcattt tcgcgaaaag cttcggcggc gggcaggtcg
     7081 acatcgtgtc gggcaagttc gtcttttcct gtaccgaggc gtataaggtc gagaatggca
     7141 agctgggcga tccgatcaag ggcgcgacgc tgatcggcga tgggccgacg gcgctgacca
     7201 aggtgatcgg catcggcaac gactgggcgc tggacgaagg catcggcatg tgcggcaagg
     7261 gcggacagag cgtgcccgcg ggcgtgggcc agccgacgct gctgatggag ggccttacgg
     7321 ttggcggtac ggcgacctga gccacttacg ccatgggcgg aggaaccagc gccacggtcc
     7381 gtctttatcc cttcatgaac atgttgaccg acagccatga tgcggtgacc gcggactggg
     7441 cggccgcctt gctggatttc tggttcaacc agaccggcga gcagggctgg tggagtcacg
     7501 acccggcgtt cgaccggacg tgccaggcgc gcttccggac cttgtgggag gaaaagcgcc
     7561 tgttgcccgc cgaagcgttt ctggatcgcg ccgacgacgc gctggccgct gtactgctgt
     7621 tcgaccagtt gccgcgcaac atgttccggg gttcggcgac cgcattttcc accgatccgc
     7681 tggcccgcga cgtggcgcgc ggggcgatcg cccatggtta tgacatacag attggcggcg
     7741 cggggcggct gttcttctat attccctttc agcatagcga agcgatggag gatcagaaat
     7801 tgtcgctcag ccttttcgca ggggcgggcg acgcgcaatc gctggccttc gcgcgggaac
     7861 atcatgccgt gatcgagcgc tttggccgct ttccccatcg caacgccgtg ctggggcgtc
     7921 ccaccctgcc cgaggaggcc gaggctgcgg cgcggggcgc gggctggtag gctgctcaat
     7981 ttttaggcag atggcgttcc gtgcctgttt tttcggcggc gtcttttgac ccaccgcatc
     8041 ggaaccccgc attaacccgc cttttacgaa ttggcacgcc tcttgctgag tgtgtccccg
     8101 cacaccagta atagggggcg acatgaaact tgtcatggct atcatcaagc cgttcaagct
     8161 tgacgatgtc cgcgaggcac tttcctcgct cggcatcgcc ggcatgacgg tgagcgaagt
     8221 gaagggcttc ggccgccaga aggggcagac cgaaatctat cgcggcgccg aatattcgac
     8281 caacatggtt ccgaagatca agatcgaggt ggtctgcgac gacgacctcg cgccgcgtgt
     8341 ggtggaagcc atccaggcag ccgccaattc gggcgccatc ggcgatggca agatcttcgt
     8401 cctcgatgtc gagcaggcgg tgcgtatccg taccggcgag accggcgaaa ccgcactgta
     8461 agaaggggga attgatgacc ttttccaaga agctttgcgg cgcgatgggg gcagtcggcc
     8521 tgtccctgct cgcagccgca ccggcgctgg ccgcgccgat caagggaccg gacgccgccg
     8581 ccatggcggc catggtcaac aagggcgacg tcgcctggat gctggtttcg gccgcgctgg
     8641 tgctgatgat gtcggtgccg ggcctggccc tgttctacgg cggcctggtc cgtaccaaga
     8701 acatgctgag catcctgatg caggtgttca tgatcgtttc cgtcgccggc ctggtctggt
     8761 gctgctgggg ctattccatc gccttcacgt cgggcggctc gaacccgttc ttcggcggcc
     8821 tgtccaaggc cttcctgatg ggcgtcgacg gcacgaccta tggcgcgacg ttcagcaaca
     8881 acgtctatct gcccgaattc gtgttcgtgg tcttccagat gaccttcgcc atgatcaccc
     8941 cggcgctgat cgtcggcgcc ttcgcggagc gtgtgaaatt ctcttcgctg atcgtgttcg
     9001 tcgtgctgtg gctgaccgtg atctatttcc cgatggccca catggtctgg tattgggccg
     9061 gcccggactt cctggtcgat gcgcctaccg actatggcct gctctggggc tggggcgcgc
     9121 tcgacttcgc gggcggcacc gtggtgcaca tcaacgccgg tatcgccggt ctggtgggcg
     9181 cgttgatgat cggcaagcgc gtcggcttcc ccaaggaacc catgccgccg cactcgctga
     9241 ccatgaccat gatcggcgcc agcctgctgt gggtcggctg gttcggcttc aacgccggtt
     9301 ccaacctgga agccaatgcc gtcaccggcg tcgccttcat caacaccatg gtcgccacct
     9361 gcgcggcggc ggtgagctgg tcgctggtcg aacaggtcca ccatggcaag gcttcgctgc
     9421 tgggcgccgt caccggtgcg gtggctggtc tggtcgcgat caccccggct gcgggcttcg
     9481 cggctccgat gacctcgatc gcgctcggct tcatcgtctc cccgatatgc tacatcttcg
     9541 tggcgttcgt gaagggcaag gtcggctatg acgacagcct ggacgtgttt ggcgtgcact
     9601 gcatcggcgg gatcgtcggc gccatcgcga ccggcatcgt cgcggctccg tcgctgggcg
     9661 gccagggcgt gttcgactac accgtcttcc ctgcggcctt ccatccggaa gcctacagca
     9721 tcccgaccca ggtctggatc caggtcaagg cggtggtctt caccctgctc ttctccggca
     9781 tcggcagcgc gatcctctac ttcatcatcg acaagaccct gggtctgcgt ccgagcaagg
     9841 aagccgaaat ggaaggtctc gacctctcca gccacggcga acgcgcttac aactactgag
     9901 attggcaggg cgggccggaa agaacggccc gtccgcctca ccttgttcct cctgcgaaca
     9961 tgcctcggga ccggtacgaa agtatcggtc cctttttttg tcagtcgcgg ggacgggtcc
    10021 agagcctgtt cgggcgcggc gttccggcgg gccagcggct ggcgcggcct ggaatctgga
    10081 ggcctgcgct gacgacccag cggatcttgt cgctcttcgc ggtggcgacg cggtggtccc
    10141 aggcatgttc gccccggcgg gcgacttcgc gggcgatgtc gccatagatg cccgcggcgg
    10201 ccagcaccgc ccaggcggcg cgcggcggca gggcgccggt gccgtggcgg gcgctttcct
    10261 cataggcggc ggccatgtcg gccagacggc gggccaggat cgccaggcgc gggcggaccc
    10321 agggcttcat atgctcgccc ggcgggatgt ccatttcgac cagccattcc tccggcaggt
    10381 agcagcggtc ggcggcttca tcctcgctga tgtcgcgggc gatattggcg agttggaagg
    10441 cgaggcccag gtcgcaggca cggtccagcg tggcttcgtc atcggggtcg acgcccatca
    10501 ggatcgccat catgcagccg accgtgcccg cgacatgata gcaatagcgc agcatgtccg
    10561 ctgcgctgcg ggggcgccat tcgcgggcgt ccagggcgaa gccttcgatc aggtcatggg
    10621 cgtagcgttc cgggatcgcg cattcgcgca tgaccaggcc gaagccgtcg aaggccggat
    10681 cgcctgtggg ttcgccccga agcgcggcag cggtgaggac gcgaatggag gacaggcgcg
    10741 cctgaccgtc agccacaccg cgcatcgtgc cgccatggtc ctgcccgtcc gctatgtcgt
    10801 cgcatttgcg gcaccaggcg tagagcagcc aggcccgttc gcgggtctgg cggtcgaaga
    10861 gtttggaggc aagggcaaag gatttggagc cgcgagcgat gctctcgcgg gcctgggcga
    10921 tgagggttgc gcggtcggga aaagaagagg aagagggcac attgctgaca tgccctcccc
    10981 cgacccctcc cgcaagcggg aggagagcga aaaagtcaga ggcggtccgc cttcatcgcg
    11041 aagatggttt cgtggggctg ataggccgcc atcctgtcga gcagggcttc gatggcgttg
    11101 gcgtggatca ggatattggc gtgctgggcg cggatgaagc cagcctccac catatgctgg
    11161 ttgaaggcga tgagctggtc gtagaaaccc gcgacgttga gcaggccgac cggcttctgg
    11221 tgatagccaa gctgcgccca actgatcgct tcccataatt cgtccatcgt gccgacgccg
    11281 cccggcaggg tgacgaagcc gtcggacagg tcggtgaaca gttgcttgcg ctggtgcatc
    11341 gtctggacga cgtgcagttc cgtgcagccg cgatgggcga cttcggcgcc gaccagcgct
    11401 tcggggatga tgccgatcac ttcgccgccc gcttccagcg ccgcgtcggc caccgcgccc
    11461 atcaggccaa ggcggccgcc gccatagacg acgccgatgc cgcgctgggc cagggtgcgc
    11521 ccgacatggc gggcggattc gacataggcg gggtccgccg gggtggccga gccgcaatag
    11581 acagccagtc tcttcatctt tccctacacc agatcttcca gcatcaacgc ggcggtcgcc
    11641 ttcgcgctgc cgaccacgcc ggggatgcct gcgcccggat gcgtgcccgc ccccaccaga
    11701 tagaggttgg gaatgacgtc gtcgcgatta tgggcgcgga accaggcgct ttgggtgagc
    11761 agcggcgcca ggctgaaggc gctgccgaga tgggccgaca aatcctggcg gaaatcgggc
    11821 ggggcgtagt gaaactgcgt cacgatgcgc gatcggatgt cggggatcag gcgatgctgg
    11881 atttcgtcca gtatgcgttc ggcatagacc ggcccgaacc gttcccagtc gatcggcagc
    11941 ttgcccagat gcggcaccgg ggcgagcgcg tagaaggtcg aatggccgtc cggcgccatg
    12001 ccgggatcgg tgacggtcgg gtggtgcaga tagagcgaga aatcctgcgg cagcacgcca
    12061 taatcgtaaa tgtcggtcag cagcccccta tagcgcgggc cgaacaggat catatggtgc
    12121 gggatgcccg gccagcttcc cttgatgccg aaatgcagca cgaacaggct gggcgaccag
    12181 cgtttgcggg aaagcttttc cgcctgtttc tggccacgcg gatggtggcc gatcaggtcg
    12241 cgatagctgt gcatcaggtc ggcgttggag gcgacggcgt ccgcctcccc ccgccagccc
    12301 gaagcggtgc gcacggcgac ggcgcggtcg ccataggttt cgatcctggt caccggatcg
    12361 gccaggcgca gcgtgccgcc cagacgttcg aaatgcgtcg ccatcgcctg gacgaggcgg
    12421 ttggtgccgc ccttcgcgaa ccagacgccg ccatccttct ccagcttgtg gatcagggcg
    12481 tagatcgaac tggtctgcat cggattgccg ccgaccagca acgtgtggaa ggaaagcgcc
    12541 tggcgcagct tctcattctt cacatgggaa gagacgaccg aatagacgga ccgccacgcc
    12601 tgatgcttca tcaacgccgg ggcggcgcgc accatcgagg cgaagtcgag aaaggcgacc
    12661 gagccgagct tgcgataccc ctcctgatac acgccgtcgg catagtccag gaagctctca
    12721 tagcccgcca catcttccgg gttgagcttg gcgatctcgg cgcggagggc ggtttcgtcg
    12781 ttggaatagt cgaaattcgt gccgtcgccc cagttgagcc ggtaaaaggg ggagacgggg
    12841 atgagggtga catcctccgc catgtcgtgg ccggacaggc gccacagttc gcccaggcaa
    12901 tccgggtcgg tgatgacggt cggtccggcg tcgaagacga agccgtcctt ttcccacata
    12961 taggcgcgtc cgcccggccg gtcccgcgcc tcgaccagcg tggtgtcgat tccggcggat
    13021 tgcaggcgga tggcgagcgc gaggccgcca aagcccgcgc cgatgacgat cgctttccgg
    13081 ttcatcgcgg cctgttcatc gggcgggtgg gctcaacaat gttcgcatgg cgtcccttat
    13141 gggcacgggg ggccgcccgc acaagatgcg gatgcgatcc cccagcgtcg agcgcccggc
    13201 atagaagcgc ccgatcagcg cagggccaag ccgatagaaa cgctcgaaga tgcgccagcg
    13261 ctgtgcgggc cgggccgcgc cgaacagcat gcggccgagc agccggtaat agcgcccctg
    13321 ccgccagtgg atggcggccc attcgcgcgt cacatgcgcc agcaggcggc cctccatcgg
    13381 ccattcgtcc gccaggcgca gcgcgaagcg caccgcgtcg ggcagggaat agccggtcat
    13441 gggctggaac atcgcggccc tcacccccgt ccgcgccaca gcgtccgcat ccagccagaa
    13501 acggtcgaaa tcgccgccat ggacgaccgg caggacgccg ctttcgctgt ggacgacccc
    13561 ctcgacctgc cagccccgcg cctgtgcata ggcggcgatc cgggcttcca atgcggggat
    13621 gtcgaggtcc ggcgtgtcgc tgtaataggt atcctcgacg aagagggtgc ggtcgtccca
    13681 gggcagcaga tagacgaagc gatagccgtc cagttgatcg acggtggcgt ccatgatgac
    13741 cgggcgggtc aggccgtgcg gggcgcgcag gcgcagcgtc tggccgacga atttctgcca
    13801 gccgcagcgc agggcggaca gatcgccccc tcccctggcg tcgagcaccg ccctggcgcg
    13861 gatgatgcgg ccgtcggaca gggtgacggc ggtgggcgtc aattcggcgg cctgcgcgcc
    13921 ggtcagcacg gcgtcgccca gcacctggcg gacatgggcg tcgaggcgcg tcgaggtgat
    13981 gctgttatag ggcatggcaa gtcgacggct gtgaccgggg aagcgaacct catagccttc
    14041 ggcccagcga tgggcgatca gcgggtcgac aagccagcga tccccggcat ccacatcgct
    14101 gtcgaaaaag gaccagatat gattgccgcc cagcgtgtcg ccgctttcca gcagcagcag
    14161 cgccgcgtcg ggatggcgcg ccgcgaaggc aagcgccgtc aggctgccgg ccaggccgcc
    14221 gcccactatc gccagatcga aatcggtcat ggtcgccatc gcatccttgt tagagcgcat
    14281 gcggggaaat gcacggattg atttccggcc cattataggg taggggggta tcctatgcat
    14341 atcgtggcgg accgggacaa gctgttggcg cgggtgcggc gcatcgccgg gcagatcggc
    14401 gccgtcgaac ggcaattgtc gggcgatgcg ggctgttcgg aaacgctgca actggtcgcg
    14461 tccgtccggg gggccgtggg cagcctgatg gaagaattga tcgagcagca tatgcgggaa
    14521 catgtcgccc gcccggatat cagcgacgaa acgcgacagg ccgcggcgga ggaaatgctg
    14581 gcgctgatcc ggcgctacgg gaagtgagca tgcatgacga tcacgaccat ggcggccacc
    14641 cgcatcctgg gcatgatcat gcgcatgccc tgccggcagt cggcggggac gaggaaaacc
    14701 attatttcga ccatatctac ctgacccatg ggcatgacga aaatgcccgc aagacgatgt
    14761 gggtggtgtg gctgactgcg gcgaccatgg tggtggagat cgtcttcggc tggctgaccg
    14821 ggtcgatggc gttgctggcc gacggcttcc acatggcgac ccatgcgggc gcgctggcgg
    14881 tggcggcggc ggcctatggc tatgcgcgga ggcatgcgcg caatccgcgc tataccttcg
    14941 gcaccgggaa ggtgggggat ctgtccggct tcgcatcggc gctgatcctg gccttcaccg
    15001 ccctgttcat cgccgtcgaa tcggtgatgc gcttgttcga accggtgaag gtggcctttg
    15061 gcgaagcgac tttggtcgcg gtgaccggcc tggtcatcaa cctgatcagc gccgtgctgc
    15121 tgcggcatga ccatagccat gatcatagcc gcgacgatgg gcatgggcat gaccccaaac
    15181 agggccatgc cgacaataat ctgcgcgccg cctatgtcca tgtgctgacc gatgcgctga
    15241 catcggtgct ggcgatcgtg gcgttgctgg cggggcgctt tatcggctgg tggtggctgg
    15301 accccgcggt gggcctgctg ggcgcggtgg tgatcgcgcg ctgggcctgg gggctgatgc
    15361 gggataccgc cgcgatcctg ctcgacaccg ccgaaccggc gctgacggcg cggatcaagg
    15421 ggctggccga ggcggaaggg gccaccatcc gcgacctgca cgtctggcgc atcgggccgc
    15481 atgcccatgc cgcgatcgtc agcctggccc ccggcgcgga cgtcgctgcc gtgcgccgcc
    15541 aggtccgcgc cctgccgcgc atggagcatg tgacggtgga gtgcggatag aatcgggcaa
    15601 gggctggccc aacctgatct ggatcacttg actcgactcg gcgggtcatc cagcttcccc
    15661 tgcgaaaatc aaaaaaatac cgtcggagag gaggccttat gcctatagcg aagccttttg
    15721 cgggaaagat ttttcacgcc ctgttgaggg aatgtttcgc ccagcagcgt ccacccaccg
    15781 acgaggaagt ggactcggtg gcttcccaga tctggcagga cagccatgga tcgatgacgg
    15841 ggcagaattg gcgggatgtc gccaagggaa gcgacgcgca ccggcagatg atcaacgcgg
    15901 cgttgatggc gttcggttcg gcgccttcgg agctgcatat ggaagcgtcc tgaggtcgat
    15961 attttagggc gggtgactgg cgccagctcc atcctcattc gtcatgcggc ggcctatggc
    16021 aaggcaaggc gcgtatgaga aaattctcag tggcatcttg aaacgggaat aggccttcct
    16081 atttccgtct tgtcccggct ctccccccct cccgccggga cacccatcat tgtggccccg
    16141 gcgttccctt gcgccggggc tgcttttttt gaggatcaaa gaaactgggc cgctacccag
    16201 ccgctcgccc aggcccattg gaaattatag ccacccagcc agccggtgac gtcgaccgct
    16261 tcgcctatgg cgtagaggcc ggggaggtgg cgcgcctcca tcgtctggga cgatagtccg
    16321 gcggtcgaga tgccgccgat ggcgacttcc gccttggcga agccttcggt gccgttgggg
    16381 gtgaaggacc aggccgaaag gcggcgttcg gcgtcctgga gcttgcggtc cggcatattg
    16441 ccgaggtcgc cgggaagcgc gagccgttcc gccagggcat cggccagacg atccggcaga
    16501 tggccgcgca ggcattgcgt cagcgtggcg cggggcctgc tgcgtttcgc gtcgatcagc
    16561 cagccttgcg gccggtcggg caggaaatcg agggcgatgg cctccccatg ccgccaatag
    16621 gaggaaatct gcaaaatcgc cgggccggac agcccccggt gggtgagcaa tgcggcttcg
    16681 cggaaggcgg tcttgccgtg gcgggcgacg acttcggtcg agacgccgga gagcgagcgg
    16741 aacagcaggt cttcgccgcc caacgtcagg gggacgagcg cggggcgcgg ctccacgacc
    16801 ttcagcccga actggcgggc aaggtcgtag gcgatgccgg tcgcgccgat cttcgggatg
    16861 gcggggccgc cggtggcgat gaccagcgcg ggggccgtgg cggtcctgcc gccatgggtg
    16921 acgctgtacc gaccatcggc atgggtgacg gaggaaatgg cgtggtcgag ccggatcgtg
    16981 acgccgcccg cttcgcattc ggccagcagc atggcgacga tctggcgggc gctccggtcg
    17041 cagaaaagct ggcccagcgt cttttcatgc caggctatgc catggcgttc gacgagcgcc
    17101 aggaaatcct gcggcgtgta acggcccagc gccgatttgg cgaaatgcgg gttgaccgag
    17161 aggtaacggt cgggcgcggt gtggatattg gtgaaattgc agcggccacc gccggagatc
    17221 aggattttct tcccggcctg gtcggcatgg tcgatgacga ggacgcgcct gccccgctgg
    17281 cccgccatgg ccgcgcacat gaggccggcg ccgccagcgc ccaggacgat ggcgtcataa
    17341 ttttccgctt tggaagccat caaccggcgg ctagcgcgtc catgatctgg cggacgggcg
    17401 cgacgtcata accggccgat gcggcctgtt cggtcagcgc cgccgggtgg tcgcccgcgc
    17461 gggcgcgggt cagcgcccag agcagggtgc tgcgcgtgcc ggaacggcaa taagcgagta
    17521 tcttgccctc ccccgcctgt tcgagcgcgg cggccatgcc gtcgagttgc catggagcaa
    17581 agccgccatg ggcgaccggg accgcggcat aggcgatgcc tgcggccttg gcggcggcct
    17641 ctatctccgc gccgttggtc tggcccggtt cctcgtcatc ggggcggttg ttgacgatca
    17701 tcgtcacgcc cagcgccttg gcctccgcca cctgatcgac gctgatctgc ggggcgacgt
    17761 agaggttctt ggtgagctgg cggaacatgg gcgggactcc tttgcgggtc tccttgcgct
    17821 tgtggggcgc aggattcaag ggggagcgcg ccagtctatg atttacagat aaggccggat
    17881 cgccgccagg aaggcgtcgc cataggcgtc cagcttgcgc tggcccacgc cgctgatgtt
    17941 gccgagttcg gcaaggctcg tcgggcgctg ctccgccatt tcgcgcaggg tcgaatcgtg
    18001 gaagatgaca tagggcggca cgcccgcctc ctgcgccagt tcgcggcggc aggcgcgcag
    18061 cgcgtcgaac agcggatcgc ccacgggatt ttcggcgctg ccgctgcggg cgctcttgcg
    18121 gcggcgttcc ttgcggggcg gcaggatcag gctgacctct tcctcgccgc gcaggatcgg
    18181 gcgggcgttg ggaccgaatt ccaggccgcc atgttcgttc gtctggagcg cgtcgcggac
    18241 cagcaatgcg cgggagacgg ggcgcagcag cgccgtctcc tccccgtcga cgatgccgta
    18301 gaccgaaatc ttgtcatggc cccgctcgcg gatcttgtcg ctgacggcgc cggtcagcac
    18361 ttgctcgata tggccgacgc cgaagctctg gccggtgcgg tagacggcgg acaggaattt
    18421 gcgggcggtc tgggtcgcgt cgatgctggg cgggggattg aggcaattgt cgcaattgcc
    18481 gcagcccggc gggggatttt ccccgaaatg gcggagcaat atggcgcggc ggcaggtgcc
    18541 ggtttccacc agtccgccca gcgccgtgat gcgggcgcgc tcgccctgct ggcggagggg
    18601 gtcgagttcg ccgatgcgct ggcgggcgcg ggcgaaatca tcggcgcccc agaaaagatg
    18661 cgcttcggcg ggttcgccgt cgcggcccgc gcggccggat tcctgataat agccctcgat
    18721 cgacttgggc agcgccgcat gggcgacgaa gcggacgtcg ggcttgtcga tgcccatgcc
    18781 gaaggcgatg gtggcgacca tcaccatatc ctcgctggcg atgaaggcgg cctggttggc
    18841 ggcgcgcatc tggggggcca gcccggcatg ataggcgcgg gtcgggcggc cggtcttgcc
    18901 aagggtttcg gccagcttct cggtcgcggc gcgggtgggg gcgtagacga tgccggggcc
    18961 ggtctggccc gcgatcaggt cggaaagctg gcgcggcagg ccgtcgcgag ggtggacggc
    19021 gtagcggatg ttcggccggt cgaagcccgc gatgatcagg ccttcgcggg gaatgccgag
    19081 ctggacgagg atgtcgtcgc gggtgtgatg gtcggcggtg gcagtcagcg ccaggcgggg
    19141 aacgtcggga aattcgtcca gcagcgggcg cagcaggcga tagtcggggc ggaaatcatg
    19201 gccccattcg gatacgcaat gcgcctcgtc tatggcgaag agggcgattt tcgcggcgcg
    19261 caggaggttg cggaaccctt ccccgctggc gcgttcgggg gcgacgtaga gcaggtcgag
    19321 atcaccgttg cgcagccggt cctgcgtctc gcgccagtcg gtatcgacgc tggtgaggct
    19381 ggcggcgcgg atgccgacgg cctgcgcggc gcgaagctgg tcgtgcatca gcgcgatcaa
    19441 tggggagacg acgacgcagc agccgtccag cgccacggcg ggcagttggt agcagagcga
    19501 cttgcctgcg ccggtcggca tgatcgccag cgtcggctgg cccgccatga tgcgactgac
    19561 cacctgttcc tgcacgccgc gaaaagcggg gaagccgaaa atatcgtgga ggagggtcgg
    19621 gatgtcgggg cgcatgggtg gggctgtagc gatttgaggg cggtggggcc agcttccctc
    19681 tatcggagga ctcacggttc cagcaggcag ccccagccct tgcgatagcg cgccgtgcgg
    19741 gagacgagca aggggaccgc cgcgttgacc gattgggatt cgggcatgtc cttcagcgac
    19801 actgcccaca tgccgggttc cttgtcgccc ttgcagcttt ccatcgagcg gccctcgaca
    19861 tagcggcagg agcaggcgac gcgcgcgccg aagcccgcgc cgacctgggc atgggcgcgc
    19921 agggcgctcc agttccaggc gaacagggcg agcggcagca gggccgctgc cagcgctcca
    19981 taaatccatt tccggcggac ggacatgctc ccctttcccg cgctccgtgt taaggcgcag
    20041 cttatgaggg ttgagcggaa cagcgtaaag cgccttggcg cgatcggcgg aattttggcg
    20101 atgctggcgg tggccggcct gtggaccgtg cgcgccgccg ggccggagcc ggtcgtccat
    20161 atcgccggag attcggatgt ggacgcggcg gcgctgaggg cggcgatcga tccgctgttc
    20221 gaggatcagg cgggcgagac gcgggcgctg atcgtcatgc acgacgggga gatcgtggcc
    20281 gagcgctatg cgccgggcta tgggccgcag accaggctgc catcctggtc cacggccaag
    20341 agcgtgacgg cggtgctgat cgggctgatg gtgtcggacg ggcggctggc gctcgattcg
    20401 cccgcgccgg tggcggcctg gggccagccg ggcgatccgc ggggacgcat caccctgcgg
    20461 cagttgctgg ccatgacatc cggcctggat catgtcgagg atgccgaacc cctggccgag
    20521 gccgatacgg tgcggatgct gttcaccgac ggggcgcagg acatgggcgc ctttgcggag
    20581 gccaagccgc tcgcccatgc gccgggttcg gtcttttcct attcgaccgg cagcacgatc
    20641 atcctgaccg acctgatggc ccggatgctg accaacagta gcgatcccga tgtgcggcgg
    20701 cgggcgatgc agatgttcat cgacgggcgg ctgaagattc cggcgcggct cgacagcctg
    20761 accgtcgaat atgatgcggc gggcacgatg atcggcggca gcttcatgca tatgacggcg
    20821 cgggattatg cgcgcttcgg ggaattgctg cgcaaccatg ggcgcggggt ggcggggcac
    20881 cagatcgtgc cggaaaagtg gatcgaccat atgcgcgcgc cttcgccgcg caacgcggcc
    20941 tatggggcgc atctgtggct caaccgggaa agcgaagaaa gcgcgctgat gccggggcgg
    21001 gcgccgcgca gcctgttcgg ctgcgtcggg catggcgggc aatatatatt ggtgtcgcca
    21061 tcgcagcggc tgaccgtggt gcggctgggc atgtcgcccg acaaggagca gcgcggggtc
    21121 gtgaaggacg gattggcgaa gctggtgggg ctttatgcgc gttgaggggt agggaatggg
    21181 gcgcgacctc cgaattttcc cctccaccat gcttcgcctg gtccccctcc ccatctatcg
    21241 atggggagga ttaggttatt agagcaggaa attgccttct atcaccgtgc ggcaggcgcc
    21301 ggtcaggatc acgcggtcgc cggaaaggcg gcatagcagg cgtcctccgc gatgcgatgc
    21361 ctgataggcg gtgagtttcg ccttatcgag ccgcccggcc caataggggg tgagcaggca
    21421 atgggccgag ccggtgacgg ggtcttcgtc tatgcccgcg ccgggggcga agacgcggct
    21481 gaccatgtcg ctgtcctcgc cgggggcggt ggcgatcagg aggatgcttc cggccttttt
    21541 cagcgtcgcg aaatccggtt gcagggcgcg gatcgcggcg tcgtcgggat aggcgaagat
    21601 cgcatagccg ccgtcgcgcc aacgggtttc gaggacgtcg ccgcccatgg ccgcggcaag
    21661 gtccggcagc gggcttggct cggtcgtcca ggcggggagc gagagcgcat aaccgtcacg
    21721 gtcgcgcgac acggtgagta tgcccgcatg cgtcgtgcgg aagcgaacgg cggtgcgacc
    21781 gcccatcagc gcatggccgc tggccagcgt ggcgtggccg cacagcttga cctccacttc
    21841 gggcgtgaac cagcgcagcg catagtccgc gtccggatca tcgggcgtgg gcacggtgaa
    21901 ggcggtttcg gagagattat tttccgccgc gatcgcctga agcgtggcgt cgtcgagcca
    21961 ttggcccagc ggcatgaccg cggccggatt gccggtaaag ggagcgtcgg cgaaggcgtc
    22021 gacctggatg aagggcaggc tggtcacggg cggtcctttg gcatttcccg tcatgatgcc
    22081 gtcgcgaccg gcaccggaac agggccggtc gggcggaact ggtcatggcg gaacgccccg
    22141 tttccggcgg cgatgaaagg aaatgggcca gccatgcaag catggctggc ccgtgttcgc
    22201 ggctgaaggg gacgttttga ccgtcaatcc atggaaacca tggtgacgct ccccaggctt
    22261 acgcgctgcc gctcgccctc ccgcgggcga tctgtgacgg ggatggtatc gcagattggc
    22321 tgagtcgtct cgcgggaatc gcggctttgc cggaattatg cctcgattcg gcgcgttcag
    22381 ccctcaccgc actgggcgcg gtggagcagt ttctggtcgg ccagcaccag cgccatcatc
    22441 gcctccacca ccggcacgcc gcgaatgccc acgcaggggt cgtggcggcc cttggtgacg
    22501 atgtccgacg cagcgccttc gcgagtgacg gtttcgaccg ggatcaggat ggagctggtc
    22561 ggcttgaagg cgatgcggac cttgaccggc tgtccggtgg agatgccgcc cgcgatgccg
    22621 cctgcatggt tggcgaggaa gacaggcgcg ccgtctttgc ccccgtccct gctcggccgc
    22681 atcggatcgg cattctgctc gccgcgcagg cgggcggcgg cgaaaccgtc gccgatctcg
    22741 acgcccttga ccgcgttgat gctcatcatc gcggcggcga gttcgctgtc gagcttggca
    22801 taaaggggcg cgccccagcc cgccggaacg ccgctggcga tgcattccac caccgcgccg
    22861 agcgaggagc cgtccttgcg ggcgtcgtcc accagtttct cccagcgctt cgccgcttcc
    22921 gggtcggggc agaaaaaggg gttgttgtcg atctcgcccg cgtcgaagcg ggcatagtcg
    22981 atggggtcgc cgccaatctc gctgacatag gcgaagatgt cgacatccgg gatgacgagc
    23041 cgggcgaccg cgcccgccgc cacgcggctc gccgtctccc gcgccgagga acggccgccg
    23101 ccgcgatagt cgcgaaagcc atatttggcg tcataggcat agtcggcatg gccggggcga
    23161 taggccttgg cgacttcgct ataatccttg gagcgctggt cggtattttc gatcatcagg
    23221 ctgatcgggg tgccggtggt ccgcccctcg aacacgccgg agaggatgcg gacctcatcc
    23281 ggttcgcggc gctgggtggt gaatttcgag gtgccgggtt tgcgcttgtc gaggaagggc
    23341 tggatgtcgg cttcggacag gggcaggccg ggagggcagc cgtcgaccat cgcgccgatg
    23401 gcgggaccat gggattcgcc ccaggtcgag aagcggaaga cgcggccgaa ggtgttgaag
    23461 ctcatatctg cctttcgtgg gtgaggtggt tcgccctcac cctcccgccg ctttgcggcg
    23521 ggcccctccc tctcccggcg ggagaggggt tttgttactt gtccaatgcg atatcgggcg
    23581 cgtcttcggc cttcatgccg atgacgttgt agcccgcgtc gacatggtgg acttcgccgg
    23641 tcacgcccga tgccaggtcg gacagcaggt acaggcccgc gccgcccaca tcctcgatcg
    23701 tcacgttgcg gcggagcggg ctgttcagtt cgttccactt catgatgtag cggaaatcgc
    23761 cgatgccgct ggccgccagc gtcttgatcg gcccggcgga gatggcgttg acgcggatat
    23821 tttccggccc caggtccatc gccagatatt tgacgctggt ttccagcgcc gccttcgcca
    23881 cgcccatgac gttgtaatgc ggaatcacct tctcggcgcc ataatagctg agcgtcagca
    23941 ggctgccgcc ctccgccatc agggggcggg cgcgcctggc gacggccacg aagctgtagg
    24001 cggagatgtt catcgtcagc aggaaatttt ccaggctggt gtcgacatat ttgccgcgca
    24061 gttcattctt gtcggaaaaa ccgatggcgt ggaccacgaa gtccagcttg ccccaacgcg
    24121 ccctgatctc ttcaaaggcc gtatcgagct tctccatgtc cgacacgtcg cagtcgatca
    24181 ggaaatcgga acccagttcc tccgccagcg gcttcacgcg cttggccagc gcctcgccct
    24241 gataggagaa agccagttc
//
