LOCUS       NZ_CP102664            20909 bp    DNA     circular CON 07-JAN-2024
DEFINITION  Sphingobium sp. JS3065 chromosome 1, complete sequence.
ACCESSION   NZ_CP102664
VERSION     NZ_CP102664.1
KEYWORDS    RefSeq.
SOURCE      Sphingobium sp. JS3065
  ORGANISM  Sphingobium sp. JS3065
            Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
            Sphingomonadaceae; Sphingobium.
REFERENCE   1  (bases 1 to 3555142)
  AUTHORS   Li,T., Xu,J., Xu,Z.-J., Xu,Y., Spain,J.C. and Zhou,N.-Y.
  TITLE     Molecular mechanism and evolution of 1-nitronaphthalene catabolism
            in Sphingobium sp. strain JS3065
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3555142)
  AUTHORS   Li,T., Xu,J., Xu,Z.-J., Xu,Y., Spain,J.C. and Zhou,N.-Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2022) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 800 Dong-Chuan Road, Shanghai,
            Shanghai 200240, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. v0.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio RS
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/07/2024 05:42:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,942
            CDSs (total)                      :: 4,873
            Genes (coding)                    :: 4,751
            CDSs (with protein)               :: 4,751
            Genes (RNA)                       :: 69
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 122
            CDSs (without protein)            :: 122
            Pseudo Genes (ambiguous residues) :: 0 of 122
            Pseudo Genes (frameshifted)       :: 40 of 122
            Pseudo Genes (incomplete)         :: 96 of 122
            Pseudo Genes (internal stop)      :: 12 of 122
            Pseudo Genes (multiple problems)  :: 23 of 122
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:10:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1909556
            Orig. end                         :: 1930465
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102664.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20909
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20909
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20909
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10909](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10909)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(84..467)
                     /gene="crcB"
                     /locus_tag="NUH86_RS09100"
                     /old_locus_tag="NUH86_09100"
     CDS             complement(84..467)
                     /codon_start=1
                     /gene="crcB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013039902.1"
                     /locus_tag="NUH86_RS09100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09100"
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="WP_267249205.1"
                     /transl_table=11
                     /translation="MTNIFLVMAGGAVGSALRYLLGRLAGQMFPAALWPWGTFGANIIG
                     GFAMGLLAGWLARFNTGAGEPIRLLLAVGVLGGFTTFSSFSLETVLMMERGQFGMALAY
                     AAFSVIGAVGALAGGVAVMRSVA"
     misc_feature    complement(519..533)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.08"
                     /tool="antismash"
     regulatory      653..760
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01725"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01725"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="SAM-I-IV-variant riboswitch; SAM riboswitches
                     modulate the expression of downstream genes in response to
                     levels of S-adenosylmethionine; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            803..1729
                     /gene="metA"
                     /locus_tag="NUH86_RS09105"
                     /old_locus_tag="NUH86_09105"
     CDS             803..1729
                     /EC_number="2.3.1.46"
                     /GO_function="GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004212101.1"
                     /locus_tag="NUH86_RS09105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09105"
                     /product="homoserine O-succinyltransferase"
                     /protein_id="WP_267249206.1"
                     /transl_table=11
                     /translation="MPIKIADDLPARPILEAEGVMVMREADAVRQDIRPLRIALLNLMP
                     DKISTETQLARLLGATPLQVELTLVRISDHVSRNASADHMASFYRPWSDVRDERFDGFI
                     VTGAPVEQLPFEEVSYWDELRAIFDWTQTHVHRSLSICWAAQAALFHFHGVEKHALERK
                     AFGLFRHHNHMPSSPWMRGFSDNFCVPVSRWSAVRRQDILEGRGLQILAESDESGLCLI
                     GDPGRGFLHMFNHLEYDTLTLAEEYARDGGRQLPAHYFPDDDPGQQPQNHWRSHAHLLF
                     GNWINEMYQTVPFDLGAAGQAPVLTAA"
     gene            complement(1751..2446)
                     /locus_tag="NUH86_RS09110"
                     /old_locus_tag="NUH86_09110"
     CDS             complement(1751..2446)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007688492.1"
                     /locus_tag="NUH86_RS09110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09110"
                     /product="hypothetical protein"
                     /protein_id="WP_267249207.1"
                     /transl_table=11
                     /translation="MAPVRSFCVLALLAALPLVGCSKKDDDLNALDAQLTNNAVDALAG
                     QIVVDPRLAGQSQRTAKLPVLTGAAAKGLADSVKLAGGTLLATPAPVEAEVKESASMLA
                     AVASEQKKPGGNALCREQLVYGAQWASRLPEPFTLYPGAQLIEAAGAEKDGCTLRAATF
                     VTPVPQQSVMDFYYTQARRAGFDAEHKVMGGDHVLGGSRKDDGSAFFLLFTEAPGGKTS
                     VDVIADHGR"
     gene            2608..2829
                     /locus_tag="NUH86_RS09115"
                     /old_locus_tag="NUH86_09115"
     CDS             2608..2829
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017183988.1"
                     /locus_tag="NUH86_RS09115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09115"
                     /product="hypothetical protein"
                     /protein_id="WP_267252079.1"
                     /transl_table=11
                     /translation="MLNILSALIGLFTLILMIPAVFPLLGALNWLLVPVALFGAFVGML
                     SAKNGGRNFCLIVAAFGALRLFLGGGIF"
     gene            2868..3737
                     /gene="rarD"
                     /locus_tag="NUH86_RS09120"
                     /old_locus_tag="NUH86_09120"
     CDS             2868..3737
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene="rarD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004208595.1"
                     /locus_tag="NUH86_RS09120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09120"
                     /product="EamA family transporter RarD"
                     /protein_id="WP_267249208.1"
                     /transl_table=11
                     /translation="MLAAMGAYAAWGLLPIFFRLLHHVNAVEIVSQRILWSLLLVTVLL
                     LARRNLPALSAILRDRRLMLPLAGSALMIGLNWLTYVWAVNGGHVIAASLGYFLNPLVN
                     VGLGVLLLHERLRRGQAVAVGIAAVGVAVMAATALTTLWISVALALTFAFYGLIRKLTP
                     VAPMTGLGVETLLLTPPAIGYLVWLSAHGGVSFGQDMATTILLIVTGLVTTVPLVLFAT
                     AAQRLPMATLGLLQYLAPTLQFLCGILLFGEKLTVGQMASFALIWLGLILFATDSLTAA
                     RRNRLATI"
     gene            complement(3734..5059)
                     /locus_tag="NUH86_RS09125"
                     /old_locus_tag="NUH86_09125"
     CDS             complement(3734..5059)
                     /EC_number="3.5.2.3"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013039898.1"
                     /locus_tag="NUH86_RS09125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09125"
                     /product="dihydroorotase"
                     /protein_id="WP_267249209.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.1e-21, bitscore:
                     75.1, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFDLLLKNGTVHTPGGAESVDVGVSGGRIVAIGTSLGAAGEVID
                     CTGLDVLPGCIDSQVHFREPGLEHKEDLESGSRAAVLGGVTAVFEMPNTNPNTDTAERV
                     HDKLKRAHHRMWCDHAFYVGATADNAGQLKEFERIPGTAGVKIFMGASTGSLLVDDDEA
                     LSRVLASGTRRVAIHAEDEARMNARKDLRVEGDPSSHPVWRDDESAMIATKRIIDLARK
                     ARRRIHILHVTTPAELEYIARNKDIATCEVTPQHLTLAAEDAYPRLGTYAQMNPPIRSG
                     AHRDGLWHWLNQGVPDVLGSDHAPHTIEEKAKPYPASPSGMPGVQTLVPLLLNHVAEGR
                     LSLRRFIELTSSGPQRVFGLVGKGRIALGYDADFTVVDLKKRWTVGSDWLASRCDWSPF
                     EGMELTGKAVGTIIRGHRVMWEDALANQAVGEAVRFEATEFA"
     gene            5121..5858
                     /locus_tag="NUH86_RS09130"
                     /old_locus_tag="NUH86_09130"
     CDS             5121..5858
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007688484.1"
                     /locus_tag="NUH86_RS09130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09130"
                     /product="folate-binding protein"
                     /protein_id="WP_267252080.1"
                     /transl_table=11
                     /translation="MIGTTLTDRTLLRISGEEAKIFLQGLLTRDVPGLKAGEPRWTALL
                     TPQGKTLFDFILWADGDDVLIDCEAAQADALVRRLTLYRLRRKVAIAREETLAVHWALE
                     AQNRPFDPRLPALGHRWIAPPDDGDASAAFRAHRLALGVFEGAGELGQDQILWLETNAG
                     ELGGVDYDKGCYVGQENTARMHYRNKVNRRLVAVPLAEADEKRQKAALPDLGLSIELRR
                     VEDIDPAALPGWLSGAMAEQAAE"
     gene            5855..6601
                     /locus_tag="NUH86_RS09135"
                     /old_locus_tag="NUH86_09135"
     CDS             5855..6601
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007688482.1"
                     /locus_tag="NUH86_RS09135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09135"
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="WP_267249210.1"
                     /transl_table=11
                     /translation="MMRILVALLGAWLLVAPAQAETRWTLVRSYPHDPAAFTEGLFYHD
                     GALYESTGLEGESEIRKVDLKNGKVLNRRIVPRPYFGEGIVNWKDRLISLTWRHRQGFV
                     WKLNDFSPVSQFRYEGEGWGLTQDGRSLIMSDGTAQLRFLDPEKLTEERRITVTWNGRP
                     VDRLNELEYVKGEIWANIWYDSHIVRIDPRSGSVIDWLDIAPLLKASGASDSEAVANGI
                     AYDTKADRLFVTGKNWAKLFEIKIGQ"
     gene            complement(7423..8457)
                     /gene="queA"
                     /locus_tag="NUH86_RS09140"
                     /old_locus_tag="NUH86_09140"
     CDS             complement(7423..8457)
                     /EC_number="2.4.99.17"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="queA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009821187.1"
                     /locus_tag="NUH86_RS09140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09140"
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="WP_267249211.1"
                     /transl_table=11
                     /translation="MRVDLFDFDLPPESIALRPASPRDSARLLLVSGDAPFEDRTVRDL
                     PGLLRAGDVLVFNDTKVIPAQLEGMRGEARIGATLHKRLGLRQWQAFLRNAKRVRDGDR
                     IDFGAGVTALAGPRDEDGGVTLSFEGEEPVEVLLERAGRMPLPPYIASKRPTDDRDRSD
                     YQTMFAREDGAVAAPTAALHFTPDLMAALKTAGVGTETLTLHVGAGTFLPVKADDTDDH
                     RMHAEWGRIDQATADRLNAARRAGGRLIAVGTTSLRLLESACGEDGVIRPFADETRIFI
                     TPGYRFRAVDGLMTNFHLPKSTLFMLVSALMGTEKMQSAYRHAIKEGYRFYSYGDSSLL
                     LPER"
     gene            complement(8608..9381)
                     /locus_tag="NUH86_RS09145"
                     /old_locus_tag="NUH86_09145"
     CDS             complement(8608..9381)
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_function="GO:0016018 - cyclosporin A binding [Evidence
                     IEA]"
                     /GO_process="GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007710026.1"
                     /locus_tag="NUH86_RS09145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09145"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_267249212.1"
                     /transl_table=11
                     /translation="MRFTSALKTVAIGFALYASSGAALAQGGGRSAEETKKEEAAVRAE
                     QAAKQLGLDPASRLPSATVPVDPQNVWDLDLSSGGRVRIQLRPDIAPTHVERIKELTRQ
                     GFYNGLKFHRVIPGFMAQGGDPKGDGTGGSTLPDLKAEFNPMPHLRGTVSMARAQSDDS
                     ANSQFFIVFLPRMQLDKKYTVFGRVIDGMQYVDAIHQGEPPADPTLILQASIESDGKPP
                     VTALPTPPAPPAPSIIAPPVKKPAPAKKPAAPKKK"
     gene            complement(9488..9997)
                     /gene="coaD"
                     /locus_tag="NUH86_RS09150"
                     /old_locus_tag="NUH86_09150"
     CDS             complement(9488..9997)
                     /EC_number="2.7.7.3"
                     /GO_function="GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004211217.1"
                     /locus_tag="NUH86_RS09150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09150"
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="WP_267249213.1"
                     /sec_met_domain="CTP_transf_like (E-value: 2.3e-19,
                     bitscore: 67.7, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQRVGVYPGTFDPITLGHMDIIRRGAKLVDKLVIGVTTNISKS
                     PMFSDEERLDMVRRECAGIDTEIVVTGFNSLLMDFAESQGASVIIRGLRAVADFEYEYQ
                     MAGMNQQINGRVETVFLMADVSLQPIASRLVKEIALYGGPIHKFVSPTICDEVEARVAQ
                     LGLKGQ"
     gene            complement(10001..10909)
                     /locus_tag="NUH86_RS09155"
                     /old_locus_tag="NUH86_09155"
     CDS             complement(10001..10909)
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013847259.1"
                     /locus_tag="NUH86_RS09155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09155"
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_267249214.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.5e-57, bitscore:
                     190.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGAASASTLVASRAAALAVDIDHLFDLLLAVPDDPRKRLYEAMR
                     HAAMGGGKRLRPLLVQAASDLFNISRDSALRVGVAVECIHVYSLVHDDLPAMDDDDMRR
                     GKPTVHKAFDEATAILAGDCLHDLAFELLADEETHPDPFVRIELVKALALASGTSGMAG
                     GQMMDLEAERASFDLSTVTRLQQLKTGALIAFCVDAAAIMARIPPDARTRLHGYARDIG
                     LAFQIADDLLDVEGDADLAGKALGKDAAAGKETFVSLLGADRAREQARLLVEQAKAHLH
                     GHGPEADLLRAIADYIVERDR"
     gene            complement(10921..11181)
                     /locus_tag="NUH86_RS09160"
                     /old_locus_tag="NUH86_09160"
     CDS             complement(10921..11181)
                     /EC_number="3.1.11.6"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007710023.1"
                     /locus_tag="NUH86_RS09160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09160"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_267249215.1"
                     /transl_table=11
                     /translation="MAQDSMTEQGDPSQLSFEDALRALESIVRRLESGDVPLDESISLY
                     SQGEELRKRCMERLQAAEARIAKLTVDASGAVTGAQPFGTD"
     misc_feature    11345..11361
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            11350..11730
                     /locus_tag="NUH86_RS09165"
                     /old_locus_tag="NUH86_09165"
     CDS             11350..11730
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013847261.1"
                     /locus_tag="NUH86_RS09165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09165"
                     /product="hypothetical protein"
                     /protein_id="WP_267249216.1"
                     /transl_table=11
                     /translation="MKYHLSLISVAALALLSACNNNDEPEVVGGPADPMAERLANAAPV
                     ELPPMVKESHQYRCKDNSLIFVDFMSDDKTANLRTEKNGAPIKLTAAEAGKPFEAEGYK
                     VEGSGKQITATLPGKSAVSCKG"
     gene            complement(11806..12234)
                     /locus_tag="NUH86_RS09170"
                     /old_locus_tag="NUH86_09170"
     CDS             complement(11806..12234)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009821181.1"
                     /locus_tag="NUH86_RS09170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09170"
                     /product="DUF805 domain-containing protein"
                     /protein_id="WP_267249217.1"
                     /transl_table=11
                     /translation="MEWMLLPLRRYAKFSGRARPREYWMFVLFLLLCYIGVAIVEGLLG
                     LSTSDRWFQRGPWWASAGYSTRGGPLTGLFTLAMLIPNIAVSVRRLHDTDRSGWWLLIV
                     FFPIIGSIVLLIFFIMSGTRGANRFGPDPVEVGEPELR"
     gene            12341..14518
                     /gene="purL"
                     /locus_tag="NUH86_RS09175"
                     /old_locus_tag="NUH86_09175"
     CDS             12341..14518
                     /EC_number="6.3.5.3"
                     /GO_function="GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="purL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017499860.1"
                     /locus_tag="NUH86_RS09175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09175"
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="WP_267249218.1"
                     /transl_table=11
                     /translation="MSSTASQITPQVVAEHGLSPEEYDRVLHALGREPNLTELGIFSVM
                     WSEHCSYKSSRIHLKKLPTEGPQVICGPGENAGVVDIGDGQAAIFKMESHNHPSYIEPY
                     QGAATGVGGILRDVFTMGARPVANMNALRFGRPDHPKMKHLISGVVHGIGGYGNCVGVP
                     TVGGEVNFHPAYDGNILVNAMTVGVADTDKIFYSAASGVGNPIVYVGSKTGRDGIHGAT
                     MASADFGEDSEEKRPTVQVGDPFTEKLLIEACLELMASDAIVAIQDMGAAGLTSSSVEM
                     ASKGGVGIELNMDKVPQRETGMTAYEMMLSESQERMLMVLQPGKEAFAEAIFRKWELDF
                     AVIGHVTDTGRMVLVHKGETVCDIPLAPLADDAPLYDRPAMPKDEYRIWSGVQPLGEIA
                     ESADIGADLVKLMGSPDIASRRWIWEQYDHMVGADTVQRPGGDAAVVRVHGSQKGIAIS
                     TDCTPRYCYADPYEGGKQAIAECYRNISAVGATPLAVTNCLNFANPQRPEIMAQFTGCL
                     EGMGDACRALDFPIVSGNVSLYNESKATGGGSAILPTPAIGGIGLLKDVDVMATVAFKN
                     EGDAIWVIGGEGTHLGQSIWLREIAGREAGDAPRVDLAAERANAETVRALIAEGKVNAV
                     HDISDGGLAVAVTEMALAGGIGAELSVTLTTASAFGEDQGRYIVAAAQGVDIPGAVKIG
                     ATGGDKVVGMTLADLRDAHEGFFPALMDSEL"
     gene            complement(14611..15378)
                     /locus_tag="NUH86_RS09180"
                     /old_locus_tag="NUH86_09180"
     CDS             complement(14611..15378)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009821178.1"
                     /locus_tag="NUH86_RS09180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09180"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_267249219.1"
                     /transl_table=11
                     /translation="MNGRRKQRISDAFGAAAGRYDDHAGPQRLAAALVADLAQRQRPDG
                     VGRILEIGCGTGFLTRDIQARWPGAELVVTDLSPDMLARAAKGGLVAGTFLTMDGEAPI
                     FEGEWFDLILSSLAFQWFDDLEGAIVRLAGLLRPGGSLIFSTMGQGSFARWRGAHDAGG
                     VRAGIPDYPSLETLREMLARFGDAFAFDEDYVLPCGGAKGLIAHLKGIGAVVPGEGRRP
                     LPPRDLRRVMAAFEASGGDDVYQVLFGRVTRAG"
     gene            15453..16697
                     /locus_tag="NUH86_RS09185"
                     /old_locus_tag="NUH86_09185"
     CDS             15453..16697
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013847265.1"
                     /locus_tag="NUH86_RS09185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09185"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_267249220.1"
                     /transl_table=11
                     /translation="MTAPSSRIPAMDVLRGCAVMGILWMNIAAFALPEQAYFSPAAAGP
                     LSMGDIAFWTVSFMAVDGKMRALFSMLFGASMLLLIDREEMAGRDGRRAQVIRAAWLFV
                     FGLAHYLLLWWGDILMIYALVGLNALLFVRMEPLALVKWAFLFFLAHFLVCAGFIGTLY
                     AWGHAATAPGAAADISAGFADFIASLSDPAHPAIRSEYMIYGGGYAGIFLHHVALFGRQ
                     WLTTLPFIAFDTLGFMLLGMAMLKSGFLTGRWQAEQYWRTARHCFLIGLIPMAALAAWI
                     ISSRFSPLTTLGSVLAWSFPFRIPLAVGWAALILWLFTRHRNRAVMARIAAVGRLALSN
                     YLGSSLFMCAIFYGWGLGLFGHVPHRSMPLFVVAAWAVMLVWSPLWQRRFALGPAEWLW
                     RSLARRQTQKIRNSG"
     misc_feature    16704..16719
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.67"
                     /tool="antismash"
     misc_feature    16704..16722
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.56"
                     /tool="antismash"
     gene            16752..16922
                     /locus_tag="NUH86_RS09190"
                     /old_locus_tag="NUH86_09190"
     CDS             16752..16922
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_BFD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007682776.1"
                     /locus_tag="NUH86_RS09190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09190"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_025547882.1"
                     /sec_met_domain="Fer2_BFD (E-value: 2.6e-06, bitscore:
                     25.4, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVCVCNAIREKDLKEVAREGCATPCSAYARLGRRPKCGQCVPFA
                     RTIIAAERASI"
     misc_feature    complement(16780..16795)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.03"
                     /tool="antismash"
     misc_feature    complement(16927..16945)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.76"
                     /tool="antismash"
     misc_feature    complement(16928..16944)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.6"
                     /tool="antismash"
     misc_feature    17008..17023
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.79"
                     /tool="antismash"
     gene            17071..17550
                     /gene="bfr"
                     /locus_tag="NUH86_RS09195"
                     /old_locus_tag="NUH86_09195"
     CDS             17071..17550
                     /EC_number="1.16.3.1"
                     /GO_function="GO:0004322 - ferroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /GO_process="GO:0006880 - intracellular sequestering of
                     iron ion [Evidence IEA]"
                     /codon_start=1
                     /gene="bfr"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012049332.1"
                     /locus_tag="NUH86_RS09195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09195"
                     /product="bacterioferritin"
                     /protein_id="WP_013847267.1"
                     /transl_table=11
                     /translation="MKGDAKVIEYLNEVLKNELTAINQYFLHYRMLNHWGIEKLAKFEY
                     EESIDEMKHADKLAERILFLDGLPNFQLLGRLKIGETVEEILKADLELEYEALPVLKDA
                     IAYCESIRDYVSRDLFQHILESEEEHVDTLETQFEMIDRMGIQNYIQLQSKAAEE"
     gene            complement(17599..18006)
                     /locus_tag="NUH86_RS09200"
                     /old_locus_tag="NUH86_09200"
     CDS             complement(17599..18006)
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017499855.1"
                     /locus_tag="NUH86_RS09200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09200"
                     /product="(deoxy)nucleoside triphosphate
                     pyrophosphohydrolase"
                     /protein_id="WP_267249221.1"
                     /transl_table=11
                     /translation="MTIISPLLVVAAALVDADGRVLLQQRPPGKPMAHLWEFPGGKVEP
                     GEAPEIALIRELEEELGIRTHASCLAPATFASEPLGDRHLLLLLYVCRKWQGIPEARHA
                     TALQWVRPAQMYALDMPPADLPLIGLLDSLI"
     misc_feature    complement(17997..18017)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.41"
                     /tool="antismash"
     gene            18085..18270
                     /locus_tag="NUH86_RS09205"
                     /old_locus_tag="NUH86_09205"
     CDS             18085..18270
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013040618.1"
                     /locus_tag="NUH86_RS09205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09205"
                     /product="Flp family type IVb pilin"
                     /protein_id="WP_267249222.1"
                     /transl_table=11
                     /translation="MRALFRNFSFWKLIYCQRGATAVEYGLILALICLAIIGAMSNVAN
                     KTIGMWNNVTTEVLAH"
     misc_feature    18342..18356
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.28"
                     /tool="antismash"
     gene            18409..18570
                     /locus_tag="NUH86_RS09210"
                     /old_locus_tag="NUH86_09210"
     CDS             18409..18570
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013040619.1"
                     /locus_tag="NUH86_RS09210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09210"
                     /product="Flp family type IVb pilin"
                     /protein_id="WP_267249223.1"
                     /transl_table=11
                     /translation="MQFIRKMMKNEKGATAIEYGLIAALIAVAAIGAMSSLGDKLGNTF
                     NNVSGNLK"
     gene            complement(18638..20116)
                     /locus_tag="NUH86_RS09215"
                     /old_locus_tag="NUH86_09215"
     CDS             complement(18638..20116)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007682785.1"
                     /locus_tag="NUH86_RS09215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NUH86_09215"
                     /product="M48 family metalloprotease"
                     /protein_id="WP_267249224.1"
                     /transl_table=11
                     /translation="MKHLSSLAYAGLGLIALAAAPSAISQQRAIRTVSSISPQEKEAGA
                     KQHPQLLNEFSGAYAGPQAKYVEGVGRRIAVQSGLSNAQGDFTVTLLNSPVNNAFAIPG
                     GYVYVTRQLLALMNDEAELAGVLGHEIGHVAAQHGQRRQQAAQRNAIGGTLLQVLTGAL
                     LGDSGLTGLLQKGIGQGSQLLTLKFSRSQEYEADDLGIRYLASGGYDPKALSTMLASLA
                     AQSSLDARVAGSSRSVPEWASTHPDPASRVGRAARNATASGSTGTVRNRDAFLNALDGI
                     LYGDDPKQGVIEGNRFRHPDLKLSFTAPSGFGMENGASAVTVAGSGGQAQFGAAAYNGD
                     LSAYIGSVFAKLGGGNGGVPPGEVRRTTVNGLPAAWRTVRASTQSSQVDATVFAYDFGG
                     GKAYHFLLLTAAGQGFGPFSAMVQSVQRLSPQEAAAIKPRRVDVVTVKAGDTVQSLAKR
                     MAYADYATDRFRTINALTASSVLRPGQRVKIVTW"
     misc_feature    20201..20216
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.74"
                     /tool="antismash"
     misc_feature    20480..20495
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.69"
                     /tool="antismash"
     misc_feature    complement(20481..20494)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.5"
                     /tool="antismash"
     misc_feature    complement(20801..20815)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
ORIGIN
        1 ggccttggcg gcaccgcggg cacgcccctg gggagcggcg gcgggcttgc gcggaccgga
       61 gcttttgccg ggcggtcgcc ccttcatgcg acgctcctca tcacggcgac gcccccggcc
      121 agcgcgccga ccgcgccgat gaccgaaaag gcggcatagg ccagcgccat gccgaactgg
      181 ccgcgttcca tcatcagcac ggtttccagg ctgaacgagg agaaagtggt gaaaccgccc
      241 agcacgccga cagcgagcag caggcggatc ggttcacccg cgccggtgtt gaaacgcgcc
      301 agccacccgg ccagcaggcc catggcgaaa ccgccgatga tgttggcccc gaaggttccc
      361 catggccaca gggcggcggg gaacatctgg cctgcaagac gcccaagcag ataacgcagc
      421 gccgatccga cggcgccgcc tgccatgacg agaaagatat tggtcatgcc gcccgcccta
      481 gagcattttt gcaaggattg ggaagcgatc attgaccttg gaaatgagag tccgccagat
      541 gtgcagggag tggccacgat cctgcatgtc ccgcgtcctg ccttgggttc aaacttttcc
      601 tattcacccc taaagcggcg attgccaaag ccgcttcatc cgcctatcta gccgtcagca
      661 tcaagagttg gggcgacgcc caacgccaac ctgccgatcc gggcaaggtg gcactccgta
      721 aaaggaggat gtggccgatc cggcaaccaa gcggacccca gccacatcgc cagcgtcgct
      781 ccgcaacagg gaatgacgag acgtgccgat caagatagcc gacgacctgc ctgcccgtcc
      841 catattggag gcggaagggg tcatggtgat gcgggaggcc gatgcggtgc ggcaggatat
      901 tcgtccgctt cggatcgcgc tgctcaacct gatgcctgac aagatcagta ccgagacgca
      961 gcttgcccgg ctgctgggcg ccacgccgtt gcaggtcgaa ctgacgctgg tgcggatcag
     1021 cgaccatgtg tcgcgcaacg cctccgccga tcatatggcg tccttctatc gcccgtggag
     1081 cgatgtccgg gacgagcggt tcgacggctt catcgtcacc ggggcgccgg tggagcaatt
     1141 gcccttcgaa gaggtgagct attgggacga attgcgcgcc attttcgact ggacgcagac
     1201 tcatgtgcat cgttcgctca gcatctgctg ggcggcgcag gccgcgctat ttcatttcca
     1261 tggcgtggag aaacatgcgc tggagcggaa ggctttcggc ctgttccggc atcacaatca
     1321 catgccgtca tcgccctgga tgcgtggctt ttccgataat ttttgcgtgc cggtgtcgcg
     1381 ctggtcggca gtgcggcgac aggatattct ggagggacgc ggcttgcaga tattggccga
     1441 gagcgatgaa tcaggtcttt gcctgatcgg tgatccgggg cgcggcttcc tgcatatgtt
     1501 caaccatctg gaatatgata cgctgacctt ggcggaggaa tatgcgcgtg acgggggaag
     1561 gcagttgcct gcccattatt tccccgacga cgatccaggc cagcagccgc aaaatcattg
     1621 gcgcagccat gcgcatctgc tgttcggcaa ctggatcaac gaaatgtacc agacagtgcc
     1681 cttcgacctg ggcgcggccg gtcaagcgcc ggtgcttacg gcggcctaga acggtttcag
     1741 cagctaattc ctagcggccg tgatccgcga tcacgtcgac gctggtcttg ccgccaggcg
     1801 cttcggtgaa cagcaggaag aaggcgctgc cgtcatcctt gcgcgaaccg cccaggacat
     1861 ggtcgccgcc catcacctta tgttcggcgt cgaaaccggc gcgacgggcc tgggtataat
     1921 agaaatccat cacgctctgc tggggcaccg gcgtcacgaa ggtggcggcg cgcagcgtgc
     1981 atccgtcctt ttccgccccg gccgcctcga tcaactgcgc accgggatag agggtgaagg
     2041 gttccggcag gcggctggcc cattgggcgc cgtagaccag ttgctcgcgg cacaaggcgt
     2101 tgccgccggg ctttttctgt tcgctggcca ccgcggccag catggatgcg gattccttca
     2161 cctctgcctc gacaggcgca ggcgtcgcga gcagcgtgcc gccagccagt ttcacggaat
     2221 cggccagccc cttggcggcc gctcccgtca gcacaggcag cttcgcggtc cgctgcgatt
     2281 ggcctgcaag ccgggggtcg accacaatct gtccagccag cgcgtcgacc gcattgttgg
     2341 tgagttgcgc gtccagcgcg ttcagatcat catccttctt gctacagccc accagcggca
     2401 gggcggccag caatgcgagg acgcaaaaag atcgaacagg cgccatggct tcactccttc
     2461 gtaaacaggg gatgaagagc aaaggttaat ttttcgttag ggattttagt gaatccctga
     2521 attttctcag aaggtggggc cagtctccgc caattggcat cgccgcccgc cttgccgcga
     2581 cgcggaggaa gcttcattta tgccgtcatg ctcaacatat tgtcagcgct gatcggcctt
     2641 ttcacgctta tcctgatgat cccggcggtg tttccgttgc tgggcgcgct caactggctg
     2701 ctggtgccgg tcgccctgtt cggcgccttc gtcggcatgc tgtcggccaa gaatggcggg
     2761 cgcaatttct gcctgatcgt ggcggctttc ggggcgctgc gactgttcct ggggggaggc
     2821 atattctgaa cgcccggcca tcatccgaac aggcggcccg gcggggattg ctcgccgcga
     2881 tgggcgctta tgccgcatgg gggctgttgc cgatcttctt caggctgctg caccatgtaa
     2941 atgcggtgga gatcgtcagc cagcgcatcc tctggtcgct gctgttggtc acggttctgc
     3001 tgctggcgcg gcggaacctg cccgcgctgt cggccatttt gcgggatcgc cgactcatgc
     3061 tgccgctggc gggatcggcc ctgatgatcg gcttgaactg gctgacctat gtctgggccg
     3121 tgaatggcgg ccatgtgatc gccgccagcc ttggctattt cctcaatccg ctggtcaatg
     3181 tcgggctggg cgtgctgctg ctccacgaac ggctgcggcg cggacaagcg gttgcggtcg
     3241 ggatcgccgc ggtgggcgtc gccgtcatgg cggcgaccgc cctgaccacg ttgtggatca
     3301 gtgtcgcgct ggcgctgacc ttcgctttct acgggctgat ccgcaagctg acgcccgtgg
     3361 cgccgatgac gggtctgggc gtggagacgc tgctgctgac gccgcctgcc atcggctatc
     3421 tggtctggct gtcggcgcat ggcggcgtca gtttcgggca ggacatggcg acgaccatcc
     3481 tgctgatcgt caccggcctg gtgaccacgg tgccgctggt gctcttcgcg accgccgccc
     3541 agcggctgcc catggccacc ctgggcctgc tgcaatatct ggcgccgacg ctgcaatttc
     3601 tgtgtggcat cctgcttttc ggggaaaagc tgacggtggg ccagatggcg agctttgcat
     3661 tgatctggct gggcctgatc ctgttcgcga cggacagcct gaccgccgcc cgccgcaatc
     3721 gtctggcgac gatttaggcg aattcagtcg cctcgaaccg caccgcctcg cccaccgcct
     3781 gattggcaag cgcatcttcc cacatcacgc gatgcccgcg gatgatggtg ccgaccgcct
     3841 tgccggtcag ttccatacct tcgaaaggcg accagtcgca gcgggaagcc agccaatcgc
     3901 tgccgacggt ccagcgcttc ttgagatcga ccacggtgaa atcggcatca taaccgagcg
     3961 cgatgcgccc cttccccacc agcccgaaga cgcgctgcgg gccggaggag gtcagttcga
     4021 tgaaccggcg cagcgacaac cgcccctccg cgacatgatt gagcagcagc ggcaccagcg
     4081 tctggacgcc gggcatgccg ctgggcgagg cgggataggg cttcgccttt tcctctatcg
     4141 tgtgcggggc atgatcgctg cccagaacat ccggcacgcc ctggttcagc cagtgccaca
     4201 ggccgtcgcg atgcgccccg gaccggatcg gcgggttcat ctgcgcatag gtgcccaggc
     4261 gcggataggc gtcctccgcc gccagggtca gatgctgggg cgtgacctcg caggtggcga
     4321 tatccttgtt gcgggcgata tattccagtt cggcgggcgt cgtcacatgc aggatgtgga
     4381 tgcggcggcg ggccttgcgg gccaggtcga tgatgcgctt cgtcgcgatc atcgcgcttt
     4441 catcgtcgcg ccagacgggg tgggaggacg ggtcgccctc cacccgcaaa tccttgcggg
     4501 cgttcatccg cgcttcgtcc tcggcatgga tggcgacgcg ccgtgtgccg ctggcgagga
     4561 cgcgggacag agcctcgtca tcgtcgacca gcaggctgcc ggtcgaggcc cccatgaata
     4621 tcttgacgcc cgccgtgccg ggtatccgct caaactcctt caactgcccg gcattgtcgg
     4681 cggtggcgcc gacatagaag gcgtggtcgc accacatgcg atgatgggcg cgcttcagct
     4741 tgtcgtgaac ccgttcagcc gtgtcggtat tggggttggt gttgggcatt tcgaagacgg
     4801 cggtgacgcc gcccagcacc gccgcgcggc tgcccgattc caggtcctcc ttatgctcca
     4861 gccccggctc gcggaaatgg acctggctgt cgatgcagcc gggcagcacg tcgagtcctg
     4921 tgcagtcgat cacctcgccc gcggcgccca gggacgtgcc gatagcgacg atcctgccgc
     4981 cgctgacgcc tacatccacg ctttccgcgc cgccgggggt gtggacggtg ccgttcttga
     5041 gaaggaggtc gaaggtcatg tcgatgtcgc ctgctttgga tgggcttgga tatggttgcg
     5101 cagtgtccta cctaaagccg atgattggca ccaccctaac cgaccgcacg ctcctcagaa
     5161 tttccggcga ggaggcgaaa atcttcctgc aaggcctgct gacccgcgac gtgccggggc
     5221 tgaaggcggg cgagccgcgc tggaccgcgc tgctgacgcc gcagggcaag acgctgttcg
     5281 acttcatcct ttgggcggac ggagacgatg tgctgatcga ttgcgaggcg gcacaagcgg
     5341 acgcgctggt aaggcggctg acgctttatc ggctgcggcg caaggtggcg attgcgcggg
     5401 aagagacgct ggcggttcat tgggcgctgg aggcgcagaa cagacccttc gacccccgcc
     5461 tgccagcgct ggggcatcgc tggatcgcgc cgccggacga cggcgacgca tcggcggctt
     5521 ttcgggcgca caggctggcg ctgggggtgt tcgagggggc cggggaactg ggacaggacc
     5581 agattttgtg gctggaaacc aatgccgggg aactgggcgg cgtcgattat gacaagggct
     5641 gctatgtcgg gcaggaaaac accgcccgca tgcattatcg caacaaggtc aaccggcggc
     5701 tggtggccgt gccgctcgcc gaagccgatg agaagcgcca gaaggcggcg ttgcctgacc
     5761 ttggcctgtc gatcgaactg cggcgggtgg aagatatcga tcctgctgcc ctgcccggct
     5821 ggctctccgg cgcgatggcg gagcaggcgg ccgaatgatg cgtatcctcg tcgcgctgct
     5881 gggcgcatgg ctgctggtcg cgccagcgca agcggaaacg cggtggacgc tggtccgaag
     5941 ctatccgcat gatccggccg cctttaccga ggggctcttc tatcatgacg gcgcgctgta
     6001 cgagagcacc gggctggagg gcgagtccga gattcgcaag gtcgacctta agaacggcaa
     6061 ggtgctgaac cgccggatcg tgccccgccc ctattttggc gagggaatcg tcaactggaa
     6121 ggaccggctg atcagtctga cctggcggca tcggcagggc ttcgtctgga agctgaacga
     6181 tttttcgccg gtttcccagt ttcgttatga aggcgaaggc tggggactga cgcaggacgg
     6241 ccgcagcctc atcatgagcg acggcacggc gcagttgcgg tttctggacc ccgaaaaact
     6301 gaccgaggaa cggcggatca cggtgacctg gaacggccgt cccgtggatc ggctgaacga
     6361 actggaatat gtgaagggcg agatctgggc caatatctgg tatgacagcc atatcgtcag
     6421 gatcgacccg cgctcgggat cggtcatcga ctggctcgac atcgccccgc tgctgaaagc
     6481 cagcggagca agcgacagcg aggcggtggc caacggcatc gcctatgaca cgaaggccga
     6541 ccgcctgttc gtgaccggaa aaaactgggc caaattgttc gagataaaga tcgggcagtg
     6601 atttggccgg tggacgttag tgcaggacgg atattgggcg gtagcgcatg ttcttattcc
     6661 tccctgcgcg cagcgtgggg acgggaaccg cgcgaagcgt ggtggagggg aaatggcgtg
     6721 acctgcgtat cttcccctcc accagccttc ggccggtccc cctccccatc tatcgacggg
     6781 gaggattagg atagttccgc ttcctcctca tagcagcatg atcggagcga ccccgtaaaa
     6841 gccccaaacg gctccagaac tcatccggct tgaccggcac ggcgcgttcg ggtgcgcgct
     6901 cgacgcggct ccaggacgag tgcgggatat gaatttgcgg gctggagcca aggcggcatt
     6961 gccggcgggt acgggtgaca ttctgggtca tcgtcttctc ctgatgagga ggaacacgaa
     7021 accttgcgtg gtcgcttcag taccgtgcgc tttagccgtt gatgacgcgg agcaagctga
     7081 catccttcaa aacggtcccg ggctgggccc gcctgtgtgg ggtagaaacg ggccgtgctc
     7141 tagatgggcc aggagggtcg cggccgatcg cattttggag gcatgacacc cgttaaaaaa
     7201 cgtggcccgt gggcatttgc gtacttgaga gtggtgacgt tgtgctgcgg cgatcccgat
     7261 taggaagatg acagtttgca tagcccatat cctcccgatt tggaggagga cgtggaatga
     7321 caggagcaaa gcccccaggc gcggacgcat tggcgatggt gactcgaaca cgtgaccccc
     7381 gcattacgaa ggcgaccttt cccactcgaa atgccttccg ccttatcgct ccggcagcag
     7441 caggctggag tccccgtagc tgtagaaccg atagccttcc ttgattgcgt gcctgtacgc
     7501 tgattgcatt ttttccgtgc ccatcaaggc acttaccagc atgaacaatg tcgatttggg
     7561 caaatggaaa ttggtcatca gcccatcgac cgcccggaag cgatagcccg gcgtgatgaa
     7621 gatccgcgtc tcgtcggcga aggggcggat gacgccatcc tctccgcaag cgctttccag
     7681 caggcgcagg ctggtggtgc cgaccgcgat caggcgtccg cccgcccgcc gcgccgcgtt
     7741 cagccgatcc gccgtcgcct ggtcgatccg cccccattcg gcgtgcatcc gatgatcgtc
     7801 ggtgtcgtca gccttcaccg gcaggaaagt ccccgcgccg acatgcaggg tcagcgtttc
     7861 cgtgcctaca cccgccgtct tcagcgccgc catcaggtcc ggcgtgaaat gcagcgcggc
     7921 ggtgggcgcc gcgaccgcgc cgtcctcccg cgcgaacatg gtctgatagt cgctgcggtc
     7981 gcggtcgtcc gtgggacgct tgctggcgat atagggaggc agcggcatgc gtccggcccg
     8041 ttccagcagg acttccaccg gctcctcgcc ctcgaagctt agcgtgacgc cgccatcctc
     8101 gtcccgtggc ccggcaaggg cggtgacgcc cgcgccgaaa tcgatccggt cgccgtcgcg
     8161 aacccgcttg gcgttgcgca gaaaggcctg ccattggcgc aggccgagcc gcttgtggag
     8221 ggtcgcgccg atcctggcct cgccgcgcat gccttcaagc tgggcgggga tgactttggt
     8281 gtcgttgaag accagcacgt cgccagcgcg cagcaggccc ggcaggtcgc gcacggtccg
     8341 atcctcgaaa ggggcgtcgc cggataccag caacagccgc gccgaatcgc ggggggatgc
     8401 aggccggagc gcgatgcttt cgggcggaag gtcgaaatcg aacaggtcta cgcgcatggg
     8461 gcgccggtcc tcagcagcgg gtcgtcagac tgaacttgtc tcagcacggt cagggcaggc
     8521 gatctggcca tgcatcgcga tgcaccgctc ttccctcgtc atgctgaaac aagttcagca
     8581 tgacgaggga agagcaaggc ggccctgtta cttcttcttc ggcgcggcgg gcttcttcgc
     8641 gggggctggc ttcttcaccg gcggcgcgat gatcgagggt gcgggcggcg cgggcggggt
     8701 gggaagcgcg gtcacgggcg gcttgccgtc gctttcgatc gacgcctgga ggatgagggt
     8761 cggatcggcg ggcggctcgc cctgatggat ggcgtcgaca tattgcatgc cgtcgatcac
     8821 ccggccgaag acggtatatt tcttgtcgag ctgcatgcgc ggcaggaaga cgatgaagaa
     8881 ctggctgttc gcgctgtcat cgctctgggc gcgggccatg gagacggtgc cgcgcagatg
     8941 cggcatcggg ttgaattccg ccttcaggtc gggaagcgtc gagccgccgg tgccgtcccc
     9001 cttgggatcg ccgccctgcg ccatgaagcc gggaatgacg cgatggaatt taaggccgtt
     9061 gtagaagccc tggcgcgtca gttccttgat ccgctcgaca tgggtgggcg cgatgtcggg
     9121 gcgaagctgg atgcgcacgc gcccgccgct cgacaggtcg agatcccaga cattctgcgg
     9181 gtcgaccggc accgtcgcgg acggcagcct ggaagcagga tcgaggccga gctgcttggc
     9241 ggcctgctcc gcgcggacgg cggcctcttc ctttttcgtt tcctcggcac tgcgcccgcc
     9301 gccctgggcc agggcggcgc cgctcgatgc atagagagcg aaaccgatcg ccacggtctt
     9361 gagcgccgac gtgaaccgca tgaacgaagc tttcctcata tttgcccagg tgcgaatgtg
     9421 cccctgatag cgtgctcttg gcgattggca actgaacgaa ggctgagtgg agcctttagc
     9481 gaaggcttta ctggcccttg aggccgagtt gcgccacccg cgcctccact tcgtcgcata
     9541 tcgtggggct gacgaacttg tggatcggcc cgccgtaaag cgcgatttcc ttgaccaggc
     9601 gggaggcgat gggttgcagc gacacgtccg ccatcaggaa gaccgtttcg acccggccgt
     9661 tgatctgctg gttcatgccc gccatctgat attcatattc gaagtccgcg acggcgcgca
     9721 ggccccggat gatgacgctg gccccctgcg attcggcgaa gtccatcagc agcgagttga
     9781 agccggtgac gacgatttcc gtgtcgatcc ccgcacattc gcggcggacc atgtccagcc
     9841 gctcctcatc ggaaaacatg ggcgatttgg agatgttggt cgtgacgccg atcaccagct
     9901 tgtcgaccag cttcgcgccg cgccggatga tgtccatatg acccagagtg atcggatcga
     9961 acgtgccggg ataaaccccc accctctgct tgctcatgcc ctagcgatcc ctttccacga
    10021 tatagtccgc gatggcgcgc agcaggtcag cctccggacc gtgcccatgc agatgcgcct
    10081 tggcctgttc caccagcagg cgggcctgct cccgcgcccg atccgcgccc agcagcgaga
    10141 cgaaggtttc cttgcccgcc gccgcatcct tgcccagcgc cttgccggca agatcggcgt
    10201 ccccctccac gtcgagcagg tcgtcggcga tctggaaggc caggccgatg tcgcgcgcat
    10261 agccgtgcag gcgggtgcgg gcgtccggcg ggatgcgcgc catgatcgcg gcggcatcga
    10321 cgcagaaggc gatcagcgcg ccggtcttca attgctggag ccgggtgacg gtggacaggt
    10381 cgaagctcgc cctttccgcc tccagatcca tcatctggcc gcccgccatg ccgctggtgc
    10441 cgctggcgag cgccagcgcc ttcaccagtt cgatgcggac gaaggggtcg ggatgggttt
    10501 cctcatccgc cagcaattcg aaggccagat cgtgcaggca atcgcccgcc aggatcgccg
    10561 tcgcctcgtc gaacgccttg tgcacggtcg gcttgccccg gcgcatgtcg tcgtcgtcca
    10621 tagccggcag gtcgtcatgc accagcgaat agacatggat gcattcgacc gcgacgccga
    10681 cccgcagcgc cgaatcgcgt gagatgttga acaggtcgct ggccgcctgc accagcagcg
    10741 gacgcagccg cttgccgccg cccatcgcgg catggcgcat cgcttcgtaa aggcgtttgc
    10801 gcggatcgtc ggggaccgcc agcagcaggt cgaacaaatg gtcgatatcc accgcgaggg
    10861 cggcggcgcg gctggcgacc agggtggagg cggaggcggc tccgctcatg cctgcggcct
    10921 tcagtccgta ccgaagggct gcgcgcccgt gacggcgccg ctggcgtcga cggtcagctt
    10981 ggcgatgcgg gcctccgccg cctggagccg ttccatgcag cgtttccgca attcctcgcc
    11041 ctgcgaataa agcgaaatgg attcgtcgag cggcacgtcg ccgctctcca gccgccggac
    11101 gatcgattcg agcgcgcgca gcgcatcctc gaacgacaat tgcgatggat cgccctgctc
    11161 tgtcatgctg tcttgcgcca ttcccctgca ttggcggccc ccgcccgccc ggtcaagccc
    11221 acatggtccg tcgcggccga ttccggcttt cctgtcacga aaacgtcatg acgtcagacc
    11281 agtggctggc ggacttgcgg cagttttgcg ttgacgcttg gtatagctag tgcacataga
    11341 aggaccgcta tgaaatatca tctctccctc atctccgtcg cggcgctcgc gctgctgtcc
    11401 gcatgcaaca ataacgacga acccgaagtc gtgggcggcc ctgccgatcc catggctgaa
    11461 aggctggcca atgccgcccc ggtcgagctg ccgccgatgg tgaaggaaag ccatcaatat
    11521 cgctgcaagg acaacagcct gatcttcgtc gacttcatga gcgacgacaa gacggcgaac
    11581 ctgcgcaccg aaaagaacgg cgcgccgatc aagctgaccg ccgccgaagc gggcaagccc
    11641 ttcgaagccg agggctacaa ggtcgagggt tcgggcaagc agatcaccgc caccctgccg
    11701 ggcaagagcg cggtgagctg caagggctga tccttttcat tttcctgcac atacgggccg
    11761 gccttcccta tggaggccgg cctttttatt cgatcccgtt gccgctcaac gcaactccgg
    11821 ctcccccacc tcgaccggat cggggccgaa gcgattggcc ccccgcgtgc cgctcatgat
    11881 gaagaagatc agcaggacga tgctgccgat gatcgggaag aagacgatca gcaaccacca
    11941 gccgctgcga tccgtatcgt gcagccggcg gacggacacg gcgatattgg gaatcagcat
    12001 cgccagcgtg aacaggccgg tgagcggccc gccgcgcgtg ctgtagcccg cactggccca
    12061 ccagggacca cgctgaaacc agcgatcgct cgtgctcagg ccaagcagcc cctctacgat
    12121 cgcgaccccg atatagcaga gcagcaggaa caggacgaac atccaatatt ccctgggccg
    12181 cgcccggccg gaaaatttgg cgtagcggcg caacggcaac agcatccatt ccatgggcaa
    12241 ctcccctttt gtcgtccgac tttgcgaaag ctatcatgtt ttcgcccgtg cgcgagcgtc
    12301 agcattgtct atcgggcgcg ccctcgctaa aggcgcgcac atgtccagca ccgcatccca
    12361 gatcacgccc caggtcgtcg ccgaacatgg gctttctccc gaagaatatg atcgcgtcct
    12421 gcacgcgctc ggccgggagc cgaatctcac cgaactcggc atattctcgg tcatgtggtc
    12481 ggagcattgc tcatacaaaa gctcgcgcat ccatttgaag aagttgccga ccgaagggcc
    12541 gcaggtcatt tgcggccccg gcgagaatgc gggcgttgtc gacattggcg acggccaggc
    12601 cgcgatcttc aagatggaaa gccacaacca cccgtcctac atcgaaccct atcagggcgc
    12661 ggcgacgggc gtgggcggca tattgcgcga cgtgttcacc atgggcgcgc gcccggtggc
    12721 gaacatgaac gcgctgcgtt tcgggcggcc cgatcacccc aagatgaagc atctcatcag
    12781 cggcgtggtg catggcatcg gcggctacgg caattgcgtg ggcgtgccga ccgtaggcgg
    12841 cgaggtgaat ttccaccccg cctatgatgg caatatcctg gtcaacgcga tgaccgtggg
    12901 cgtcgcggat acggacaaga ttttctacag cgccgcgtcg ggcgtcggca atcccatcgt
    12961 ctatgtcggg tcgaagaccg gccgcgacgg cattcatggc gcgaccatgg cctccgccga
    13021 cttcggcgag gattcggaag aaaagcgccc caccgtgcag gtgggcgacc ccttcaccga
    13081 gaagctgctg atcgaagcct gcctggaact gatggcgtcc gacgccatcg tcgcgatcca
    13141 ggacatgggc gcggcgggcc tcacctcttc ctccgtggag atggcgtcca agggcggcgt
    13201 cggcatcgag ctgaacatgg acaaggtgcc gcagcgcgaa accggcatga ccgcctatga
    13261 aatgatgctg tccgaatcgc aggaacgcat gctgatggtg ctgcaaccgg gcaaggaagc
    13321 ctttgccgaa gccattttcc ggaagtggga actggatttc gcggtgatcg gccatgtaac
    13381 cgacaccggc cgcatggtgc tggtccacaa gggcgagacg gtgtgcgaca ttccgctcgc
    13441 cccgctggcc gacgatgcgc cgctttacga ccgtccggcg atgccgaagg acgaatatag
    13501 gatctggtcg ggcgttcagc cgctgggcga aatcgcggaa agcgccgaca tcggcgcgga
    13561 tctcgtcaag ctgatgggct cgcccgacat cgccagccgc cgctggatct gggaacaata
    13621 tgaccatatg gtcggcgccg acacggtgca gcggcccggc ggcgatgcgg cggtggtccg
    13681 cgtccatggc tcgcaaaagg gcattgcgat cagcaccgac tgcacgccgc gctattgcta
    13741 tgccgatccc tatgagggcg gcaagcaggc gatcgcggaa tgctatcgca acatttcagc
    13801 ggtcggcgcg accccgctgg ccgtcaccaa ctgcctcaac ttcgccaatc cgcagcggcc
    13861 ggagatcatg gcccagttca ccggctgcct tgagggcatg ggtgacgcct gccgggcgct
    13921 ggatttcccg atcgtgtcag gcaatgtgtc gctttacaat gagtccaagg cgaccggcgg
    13981 cggttccgcg atcctgccca ccccggcaat cggcgggatc ggcctgctca aggacgtcga
    14041 cgtgatggcg accgtcgctt tcaagaatga gggcgatgcg atctgggtca tcggcggcga
    14101 agggacgcat ctcggccaat cgatctggct gcgggaaatc gccgggcggg aagcgggcga
    14161 tgcgcccagg gtcgacctgg ccgcagaacg cgccaacgcc gaaaccgtcc gcgccctgat
    14221 cgcggaaggc aaggtcaatg cggtgcatga catttccgac ggcggcctgg ctgtagccgt
    14281 gaccgaaatg gcgttggcgg gcggcatcgg cgcggaattg agcgtcacgc tgacgacggc
    14341 aagcgccttt ggcgaggatc agggccgcta catcgtcgcc gctgcccagg gcgtcgacat
    14401 tccgggcgcc gtgaagatcg gcgccaccgg cggcgacaag gtcgtgggca tgacgctggc
    14461 cgacctgcgc gacgcgcatg agggcttctt cccggcgctg atggatagcg aactgtaaac
    14521 gatacaaggt gacgtgctcc tgcgcaggca ggggcgcgtc acttaacgtt ggcggttggg
    14581 cgattacggc cttcgctccg atcagccccg ctaacccgcc cgcgtcacgc ggccgaacag
    14641 cacctgatag acatcatcgc cgccgctcgc ctcgaaggca gccatgaccc ggcgcaaatc
    14701 cctgggcgga agcggcctgc gcccttcacc tggcaccacc gcaccgatgc ccttcagatg
    14761 cgcgatcagg cccttcgctc caccgcaggg caggacataa tcctcgtcaa aggcaaaggc
    14821 atccccgaag cgcgccagca tctcgcgcag cgtttccagt gagggatagt ccggaatgcc
    14881 ggcccgcacc ccgccagcgt catgcgcccc gcgccagcgg gcgaaactgc cctgccccat
    14941 agtggagaag atcaggcttc cccccggccg cagcaatccc gccagccgga caatggcgcc
    15001 ctccagatcg tcgaaccact ggaaggccag gctggagagg atgaggtcga accactcccc
    15061 ctcgaaaatc ggcgcttcgc cgtccatcgt caggaatgtg ccagcgacca gtccgccctt
    15121 cgccgcccgc gccagcatgt ccggcgacag gtccgtcacc accagttccg cgcccggcca
    15181 acgcgcctgg atgtcccgcg tcaggaaacc ggtgccacag ccgatctcca atatgcggcc
    15241 gacgccgtcg ggcctttgcc tctgcgcgag atcggccacc agcgcggcgg ccagccgctg
    15301 cggcccggca tgatcgtcat aacgccccgc cgccgcgccg aaagcgtcgc ttattcgttg
    15361 cttgcgccga ccattcatgg ctagtcgcat tgacagagcc acgagccgat ttccagcctc
    15421 ttcaaggccc aattcaagga cagccacgac cgatgaccgc cccctcttcc cggattcccg
    15481 ccatggacgt gctgcgcggc tgcgcggtca tgggaatcct ctggatgaac atcgcggcct
    15541 tcgccctgcc ggaacaggcc tatttcagcc cggcggcggc tgggccgctt tccatgggcg
    15601 acatcgcctt ctggacggtc agtttcatgg ctgtcgacgg caagatgcgg gcgctgttct
    15661 ccatgctgtt cggcgcgtcg atgctgctgc tgatcgaccg ggaggaaatg gccgggcgtg
    15721 acgggcggcg ggcgcaggtg atccgagccg cctggctgtt cgtcttcggc ctggcccatt
    15781 atctgctgct gtggtggggc gacatattga tgatctatgc gctggtcggc ctgaacgcgc
    15841 tgctgttcgt gcggatggag ccgctggcgc tcgtcaaatg ggcctttctc ttcttcctgg
    15901 cgcatttcct ggtgtgcgcg gggttcatcg gcacgctcta cgcctggggc catgccgcca
    15961 ccgcgcctgg cgcggcagca gacatcagcg cgggtttcgc cgatttcatc gcttcgcttt
    16021 ccgatccggc gcatccagcg atccgaagcg aatatatgat ctatggcggc ggctatgccg
    16081 ggattttcct gcatcatgtc gccctgttcg gccgccaatg gctgacgact ttgccgttca
    16141 tcgccttcga cacgctgggc ttcatgctgt tgggcatggc gatgttgaag agcggcttcc
    16201 tgaccggacg ctggcaggcg gagcaatatt ggcggaccgc gcggcattgt ttcctgatcg
    16261 ggctgatccc gatggcggcg cttgcggcct ggatcatttc cagccgattc tctccgctca
    16321 cgacgctggg gtcggtgctg gcctggtcct tccccttccg catcccgctg gccgtgggtt
    16381 gggcggccct gatcctgtgg ctgttcacgc gccatcgcaa ccgggccgtc atggcgcgaa
    16441 tcgccgcggt cgggcggctg gcgctcagca actatctggg cagcagcctt ttcatgtgcg
    16501 cgatcttcta cggctggggg cttgggctgt tcggccatgt tccgcatcgt tccatgccgt
    16561 tgttcgtcgt ggcggcatgg gcggtcatgc tggtctggtc gccgctatgg cagaggcgat
    16621 tcgcgttggg gccggcggaa tggctgtggc gcagcctggc tcgccgccaa acgcaaaaga
    16681 ttcgcaacag cggctgaatc tctattgcga cctattatca tctgcgctat ctccacgttc
    16741 aggagatttg catggttgtc tgtgtctgca atgccattcg tgaaaaggat ctgaaagagg
    16801 tcgcccgcga aggttgcgcc actccgtgca gcgcttatgc gcgcctggga cgtcggccca
    16861 aatgcggcca gtgcgtgccc ttcgcccgca cgatcatcgc ggcggagcgc gcttccattt
    16921 aaagccattg cgagtcaggc gcatccgact gacgcgaact tgacgcaata gcgcaacaaa
    16981 aaatggcgga tttccgcggc tttccggatt aacaaacgga aacgaaacgc ttatgatccc
    17041 ggcacttcct tacagccgga gaagaacgcc atgaagggcg acgccaaggt catcgaatat
    17101 ctgaacgagg ttctcaagaa cgagctgacc gcgatcaacc aatatttcct ccactatcgc
    17161 atgctgaacc attggggcat cgagaagctg gccaagttcg aatatgagga atcgatcgac
    17221 gagatgaagc acgccgacaa gctggcggag cgcatcctgt tcctggacgg actgcccaat
    17281 ttccagttgc tcggccgcct gaagatcggg gagacggtgg aggaaatatt gaaggccgac
    17341 ctcgaactgg aatatgaagc cctgccggtg ctgaaggacg ccatcgccta ttgcgaatcg
    17401 atccgcgact atgtgagccg cgatctgttc cagcacatcc tcgaaagcga ggaagagcat
    17461 gtcgacacgc tggaaaccca gttcgagatg atcgaccgca tgggcatcca gaattatatc
    17521 cagctacaga gcaaggcggc cgaggaataa gggttcaagg gggggcggcc cgtcgggcgc
    17581 gcccgcccct ctcctccgtc agatcagcga atccagcaag ccaatcagcg gcaagtccgc
    17641 tggcggcatg tccagcgcgt acatttgcgc gggcctaacc cattggagcg cggtcgcgtg
    17701 ccgcgcttcg gggatgccct gccatttgcg gcagacataa agcaacagca gcagatggcg
    17761 gtcgcccagc ggctcgctcg cgaaggtcgc gggcgcgagg cagcttgcat gggtgcggat
    17821 gcccagttcc tcctccaact cgcggatcaa tgcgatttca ggcgcttctc ccggctccac
    17881 cttgccgccg gggaattccc ataggtgcgc catcggcttt cccggcgggc gctgctgcaa
    17941 aagaacacgg ccatccgcgt cgaccagggc ggctgcaacc accagcaggg gagaaattat
    18001 cgtcatgatg atccgacttg aggggtttgt taactctgcc gcttttacaa gggcatttgg
    18061 ggctgtgtgt aaatggggtg cggcatgcgg gcgttgttta gaaacttcag cttttggaag
    18121 ctgatctatt gtcaacgcgg cgcgacggcg gtggagtatg gattgatcct cgccctcatc
    18181 tgccttgcca taatcggcgc catgtcgaac gtcgccaata agaccatcgg catgtggaac
    18241 aatgtcacca cagaagttct ggcgcattaa ccatctatat ctgacacccc tttcatctca
    18301 ttaaatcttt atcaacccac ccccgctaca tcaatcgaag ctgaccttca tttcaagcgg
    18361 ggggcggccg ggtagttaaa cgtgtaactt gaggcaagga gacttccaat gcagttcatc
    18421 cgcaagatga tgaagaacga aaagggtgcg accgctattg aatatggcct gatcgccgcg
    18481 ctcatcgctg tcgccgccat cggcgccatg tccagcctgg gcgacaagct cggcaacacc
    18541 ttcaacaatg tctcgggcaa cctgaagtaa gctcgaacgc attgacgaaa aaagggcgac
    18601 ggaagcaatt ccgtcgccct ttttattgct ctccccctca ccaggtgacg atcttcacac
    18661 gctgacccgg ccggagcacg ctgctggccg tcaaggcgtt gatcgtccgg aaacggtccg
    18721 tcgcgtaatc cgcataagcc atccgcttgg cgagcgactg gacagtgtcg ccagccttta
    18781 cggtgacgac gtcgacccta cgcggcttga tcgcagccgc ctcctgcggg gaaaggcgct
    18841 gcaccgactg gaccatggcc gaaaaggggc cgaatccctg acccgccgcc gtcagcagca
    18901 ggaaatgata ggctttcccg ccaccgaaat cataagcgaa gacggtcgca tcgacctggc
    18961 tggactgggt gctggcccgg acggtgcgcc aggccgcggg aagcccgttc accgtggtgc
    19021 ggcggacctc gccgggcgga acgccgccat tgccgccgcc cagcttcgcg aagaccgaac
    19081 cgatataggc ggacagatcg ccattatagg cagcggcgcc gaactgcgcc tgcccgcccg
    19141 atcccgcgac ggtcacggcg cttgcgccat tttccatgcc gaagcccgaa ggcgcggtga
    19201 agctcagctt caaatcggga tgacggaaac ggttgccctc gatcacgccc tgtttcggat
    19261 cgtcgccgta taatatgccg tccaaggcat tcagaaacgc atcccggttg cgcacggtgc
    19321 cggtcgaccc gctggcggtg gcattgcgcg ccgcccgccc gacgcgggag gccggatcgg
    19381 ggtgcgtgct ggcccattcc ggcacggagc gcgaactgcc cgcgaccctg gcgtccaggc
    19441 tgctctgcgc cgcgagggag gccagcatgg tcgagagagc cttgggatcg tagccgcccg
    19501 aagcgaggta acgaatgccc agatcgtccg cctcatattc ctggctgcgg gagaatttga
    19561 gcgtcagcaa ctggctgccc tggccgatcc ccttttgcag caggccggta agccccgaat
    19621 cgcccagcag cgcgccggtc agcacttgga gcagcgtgcc gccaatggcg ttgcgttgcg
    19681 ccgcctgctg ccgccgctgg ccatgctggg ccgcgacatg gccgatttca tggccgagca
    19741 cgcccgcaag ctccgcctcg tcgttcatca gcgccaagag ctgccgcgtg acatagacat
    19801 agccgccggg aatggcgaag gcgttgttca ccggtgaatt gagcagggtg acggtgaaat
    19861 ccccctgcgc gttggacagg ccggactgga ccgcgatccg gcggcccacg ccctccacat
    19921 atttcgcctg cggtccggca taggcgccgc taaattcgtt aagaagctgg ggatgctgct
    19981 tggcgcctgc ttccttttcc tgcgggctga tcgacgaaac cgtgcgaatc gcccgctgct
    20041 ggctgatcgc ggacggcgcg gcggccaggg caatcaagcc cagccccgca taagccagag
    20101 atgataagtg cttcacgcta ccctcctgcc tcccctgtta ccatggcgta acgagggata
    20161 gcagccgcaa gttccccaaa acagggggct tatcggtcac acgccgatgg cgaggaactt
    20221 gtcggcgcga tcggtgcgca gcgcgtcggc gctcatgccg gaaagcgaat ccagttcctg
    20281 gccgatggcc gcgcccagac tggcgatcgc ctgcaccggc tcacgatggg cgccgccgat
    20341 cggctccgga acgatgcggt cgatgacgcc cagcgatttc agatgctgcg ccgtgacctg
    20401 catggcggtg gcggcgtcgc tggccttttc cgccgtgcgc cagaggatag aggcgcagcc
    20461 ttcgggcgag atcaccgaat agaccgcatg ttcgaacatc agcacgcgat tggccgccgc
    20521 caacgccaca gcgccgccag agccgccctc ccccaccacg gcggccacca tcggcacgcc
    20581 aagggcgagg cattgttcgg tcgagcgggc gatggcctcc gcctgtccgc gttcctccgc
    20641 ctgcacgccg gggaaagcgc ccgacgtatc gaccagcgtc accaccggca ggtcgaaacg
    20701 gtcggcaagc tgcatcaggc ggatcgcctt gcgatagccc tccggcttgg ccatgccgaa
    20761 attgtgtcgg acgcggctgg ccgtatcgtc gcccttttca tggccgatca cgaccacgcg
    20821 ccggtcgccc aaagtcgcga agccgccgat gatcgcctga tcgtccgaaa aggcgcggtc
    20881 cccggccagg ggcatgaaat tgtcgaaca
//
