LOCUS       NZ_CP109848            20549 bp    DNA     circular CON 22-NOV-2023
DEFINITION  Paenibacillus polymyxa strain K16 chromosome.
ACCESSION   NZ_CP109848
VERSION     NZ_CP109848.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5978518)
  AUTHORS   Manfredini,A., Vitali,F., Sas,L., Trzcinski,P. and Canfora,L.
  TITLE     Genome sequence of the Paenibacillus polymyxa K16 strain isolated
            from soil of tomato roots
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5978518)
  AUTHORS   Manfredini,A., Vitali,F., Sas,L., Trzcinski,P. and Canfora,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-OCT-2022) Research Centre for Agriculture and
            Environment, CREA - Council for Agricultural Research and Analysis
            of the Agricultural Economy, Via della Navicella 2/4, Rome 00184,
            Italy
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2022
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 270.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/22/2023 06:01:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,334
            CDSs (total)                      :: 5,275
            Genes (coding)                    :: 5,199
            CDSs (with protein)               :: 5,199
            Genes (RNA)                       :: 59
            rRNAs                             :: 3 (5S)
            complete rRNAs                    :: 3 (5S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 33 of 76
            Pseudo Genes (incomplete)         :: 52 of 76
            Pseudo Genes (internal stop)      :: 19 of 76
            Pseudo Genes (multiple problems)  :: 22 of 76
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:36:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3690746
            Orig. end                         :: 3711295
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP109848.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Strain stored in SYMBIOBANK
            culture collection of the National Institute of Horticultural
            Research in Skierniewice (PL).
FEATURES             Location/Qualifiers
     region          1..20549
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="8"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     cand_cluster    1..20549
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20549
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10549](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10549
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     misc_feature    1..17
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.74"
                     /tool="antismash"
     misc_feature    253..266
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: strong, score: 19.49"
                     /tool="antismash"
     gene            327..1790
                     /locus_tag="OF859_RS16715"
     CDS             327..1790
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371436.1"
                     /locus_tag="OF859_RS16715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="WP_023988953.1"
                     /transl_table=11
                     /translation="MKKAYRFTALVLTAVILLLTGLPMLNAYGTEAKPQKKLVVGMSAD
                     FPPYEFHKVINGKDTIVGFDVDIAKEIAKDLDAEMVPEDMSFDSLLPALQSGRVDLVLS
                     GMTPTDERRKSIDFSDVYYRSKQVIMVRPEDKDKYPTMDALKGEKIGAQKGSIQEEIAQ
                     KVPNASVTSLDKISDLVLQLRTQRVNAVVIEDTVAKGYTLDGTVTLAKAVPEDAGAETA
                     VGIRKGNAELLASVNKTLARLKADGSIEKFSTEASALSADRQVSSNNIVDIFWKYRSLY
                     ATGIGYTLLLSALGVLFGFIIGLIISLLRMSGVRIIEWLGTTYVEILRGTPMLVQLMII
                     HYGVALTLGVNFTPLQSGIITLSLNSSAYLAEIFRAGIQAVDRGQMEAARSLGMGRGKA
                     MRHVILPQAFKSILPAIGNEFITIIKESSIISTIGMVDIMYQAQVIKNITYEGLSPFVI
                     AAAIYFVMTFSLSKLLGLWERKLRASDHR"
     gene            1777..2499
                     /locus_tag="OF859_RS16720"
     CDS             1777..2499
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371435.1"
                     /locus_tag="OF859_RS16720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_013310491.1"
                     /transl_table=11
                     /translation="MITVKQLRKSFGKNEILKGIDIDIAKGEVVVIIGPSGSGKSTFLR
                     CMNLLEQPTDGEILFEGEPITARGHNINVTREKMGMVFQHFNLFPHKTVLQNLTLAPTQ
                     VRRQSGKEAEKIALELLRTVGLEDKKNTYPNQLSGGQKQRIAIARALAMQPHVMLFDEP
                     TSALDPEMVGEVLDVMKKLAEGGMTMVIVTHEMGFAREVGDRIIFMDNGQIVEQGTPEQ
                     VFGTPSHDRTRDFLAKVL"
     misc_feature    complement(2604..2619)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     misc_feature    complement(2675..2693)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.99"
                     /tool="antismash"
     regulatory      2734..2902
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            2909..3577
                     /locus_tag="OF859_RS16725"
     CDS             2909..3577
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019687404.1"
                     /locus_tag="OF859_RS16725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3D domain-containing protein"
                     /protein_id="WP_264453700.1"
                     /transl_table=11
                     /translation="MKHLKHIGKTMKFAVLAAAIAGLAQTAGVADAASLHTAKDGDTFF
                     LLAQRYGVSVDELTKANPNIASNNIYAGLQIKVPGEKSVNAASDSKPQLLTEKAPANEG
                     PAIEAWGKTFNYSKIVDVKATAYSAAADENGKWGAVDYYGNPLKLGTIAVDPNVIPMGT
                     KVLVTGYSHPGLPDHSFVAVARDQGSAITGKRIDIFIPGNKSFVNDFGFQNVKLYVIDK
                     "
     gene            complement(3776..4582)
                     /locus_tag="OF859_RS16730"
     CDS             complement(3776..4582)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820724.1"
                     /locus_tag="OF859_RS16730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_028541698.1"
                     /transl_table=11
                     /translation="MPYRGVLPGLALLLAFSSLPVHADAPPNIGTPHPKEATVASSVQQ
                     SIDRATPTLAMLRKKHADIFKMCGPHTRQIALTFDDVPDSRYTPQVLDVLHANGIKATF
                     FIVGHRAEKHPGIIRRIIREGHAIGNHSYTHPDFRKATPERFRNQITKTERILQASAGF
                     RPKLIRPPYGEITEPQIQWARRHGYMIVNWNVDSLDWKGLSKTQIQRNVIPATGPGSII
                     LMHAGGGQSSNLQGTVQALPGLIHSLKAKGYKFVTVPRLLHTSEQK"
     gene            4888..5910
                     /locus_tag="OF859_RS16735"
     CDS             4888..5910
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371431.1"
                     /locus_tag="OF859_RS16735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADH:flavin oxidoreductase/NADH oxidase"
                     /protein_id="WP_023988950.1"
                     /transl_table=11
                     /translation="MTDLFTPYQLKGLSLKNRIVMPPMCQYSVEAKDGNPTDWHHVHYV
                     SRAVGGTGLIIVEMTAVHPDGRITDRDLGIWSDEHIPAYRKIVEEVHKYGAKIGIQLGH
                     AGRKAEDAEQPVGPSSIPFSERFKEPHALKTAEVRELVQAYKEGARRAVEAGFDTVEIH
                     GAHGYLIHQFHSPLTNAREDEYGQDLSLFGVEVIHAVKEVLPADMPVLMRISAKEYVED
                     GYNVEYITGVGERYRDAGVDIFHISSGGEGPIGSGGGPSARAGYQVDLAHTIREKLNVP
                     VIAVGLLDDYEDARRVVQQKEADLVAIGRAMLRDPYWALHASRELKVQADIPEPYLRGF
                     "
     misc_feature    complement(4925..4938)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.67"
                     /tool="antismash"
     gene            5998..6666
                     /locus_tag="OF859_RS16740"
     CDS             5998..6666
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007432515.1"
                     /locus_tag="OF859_RS16740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PspA/IM30 family protein"
                     /protein_id="WP_013310486.1"
                     /transl_table=11
                     /translation="MSIFKRLRDLTMSNINAIIDKAEDPIKMTDQYIRDMQEDLEDAEK
                     AVAAQIAIEKRFKQQYEEQAALVKKREEQAHTAAKAQNVDLARRALEEKKSAEQKMNEF
                     KAGYEQNKAAADNLRGKLDEMRRQLTEMKNKRETLVARYNAAKAQTEINKAMNGFSSDT
                     ATAGLKRMEEKMLQAEARAEASNEMSSKEKSLDEEFKELDKKSAVDDELAALLKQYENK
                     "
     gene            6798..7205
                     /locus_tag="OF859_RS16745"
     CDS             6798..7205
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820726.1"
                     /locus_tag="OF859_RS16745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF350 domain-containing protein"
                     /protein_id="WP_013310484.1"
                     /transl_table=11
                     /translation="MHFLETMKAMLVWTGAGAILIFALMYVDSLFTKYKDFAEVKAGNM
                     AVTVRMIMKLVAQGYILSGSIATANNLLEALVYSVIAFVILLVLEVIVRLLLRYWAQFD
                     LDKGTQEGKIGFGLFSGALHLVGALIITACF"
     gene            7230..7736
                     /locus_tag="OF859_RS16750"
     CDS             7230..7736
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010348250.1"
                     /locus_tag="OF859_RS16750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4178 domain-containing protein"
                     /protein_id="WP_007432513.1"
                     /transl_table=11
                     /translation="MGVWKRISNLFAKPEPPKAEKSMLHLNPGDICEVSLVTYEVVGRV
                     HNRARNAVVLTLQDGNQVSYLHIEERETLQFGLYQAIDGRLDNPEEVPTILELDDTTYH
                     LEEQYSGHVTVMGRAPFRQGGEQHVWQYQSDDYHLLRVEWQDGRFMLYEGEEVITGDVK
                     VIRAS"
     misc_feature    complement(7239..7253)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 24.68"
                     /tool="antismash"
     gene            7750..8505
                     /locus_tag="OF859_RS16755"
     CDS             7750..8505
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310483.1"
                     /locus_tag="OF859_RS16755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4247 domain-containing protein"
                     /protein_id="WP_023988948.1"
                     /transl_table=11
                     /translation="MSKRTWQYALKVIVALSLFVSVLSGCGAPSVKDTYPLESVSGSGN
                     STSYVYRAAGKTVPEVAEELKEQRTPEQMSPQSNERMFLVYSDEWYHLQQDPAKKEDTL
                     IEIDSKKYVEQNYSSSFLKGYLTATVLDALFDSLRGSGSYRGYSSRDVYRPSQGQYRAP
                     TVQEKKAIPPITVERKGSVTRRGKNSDSSVGSSGSLFDRGSSSSPSRGSISRDRSDSGG
                     SSIFDSPRKSYSKPKTRSGSGKISRRSRR"
     misc_feature    8522..8535
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.74"
                     /tool="antismash"
     misc_feature    8657..8670
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.86"
                     /tool="antismash"
     gene            8692..9144
                     /locus_tag="OF859_RS16760"
     CDS             8692..9144
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310482.1"
                     /locus_tag="OF859_RS16760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SRPBCC domain-containing protein"
                     /protein_id="WP_264453701.1"
                     /transl_table=11
                     /translation="MVLSISWPDLSQRPFNLMVERKMECSPNVLYQAWTKRFDSWFAAP
                     GSVLMEAEVNMTFFFETHFEGKRHPHYGRFLRLEQNRLIELTWITGEGGTKGAETVLTV
                     ELKPRGNGTHLYLTHAGLPDENSRNQHEQAWPLVLEQLDKRMMPDR"
     misc_feature    9204..9213
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            9337..10050
                     /locus_tag="OF859_RS16765"
     CDS             9337..10050
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820730.1"
                     /locus_tag="OF859_RS16765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_071641072.1"
                     /transl_table=11
                     /translation="MLSAFLYILLGVFDALAAVILVLKLYMLPVREYRRKILFYAIGIA
                     LFSFLMREVIGLPKLDLPLQYLLMVIFFRFGLGIKTHLAAFSAGSGLTAYINLQLFVFL
                     FAYFFGVAEPGAINDTSGSSIYVIQLTSIIIACFISYIMGKYNFGFSFIIQPPHDFLRA
                     ENYLSSLNKMLILGALISAVTIFITLYMLYSSNTIGLLSISLLTFGVSYFFSERGDYED
                     ARSAITVHRNGNKKS"
     gene            10001..10549
                     /locus_tag="OF859_RS16770"
     CDS             10001..10549
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016526.3"
                     /locus_tag="OF859_RS16770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="accessory gene regulator B family protein"
                     /protein_id="WP_264453703.1"
                     /sec_met_domain="AgrB (E-value: 2e-20, bitscore: 71.2,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEALSRYIATEIKKADPDGPTSVEVMEYALGIKITEVSSILMVA
                     IIAWMTGHFFGSLLALVTIMFVRRFSGGAHFSNLTFCVCFTTAICVTIPLVSLNLSTIL
                     IINACSVLVFLVYAPNHFIYIHKTNNHKYYKTVCVLICAVNFFVQSHIICLSLAIQAFS
                     ILPLWKGGERKWIRNWREL"
     gene            10522..10653
                     /locus_tag="OF859_RS16775"
     CDS             10522..10653
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427735.1"
                     /locus_tag="OF859_RS16775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_023988946.1"
                     /transl_table=11
                     /translation="MDKKLARALNLRLGKYANESTKNEKTVFGAKPIPAELKKKEKN"
     gene            11011..12288
                     /locus_tag="OF859_RS16780"
     CDS             11011..12288
                     /GO_function="GO:0030151 - molybdenum ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371421.1"
                     /locus_tag="OF859_RS16780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="WP_264453704.1"
                     /transl_table=11
                     /translation="MNHTSLNAEKFQRKAVQVEEAQSRIASYVKQGEREDVELEQAHGR
                     YLAMDLTAPHPYPRFRRSGMDGYAILGSDTEVCSSGQEIWLHVIDEIPCGTVSDKRVET
                     GMAARIMTGAQLPEGADTVVMLEATQLREENGQTYVGLKKRIEVGKNVTQIGHEIQEGR
                     LLLSKGTCLGAGHISVLATFGVHRVPVYRKPKVAVFSTGSELLAVDEPLQPGKIRNSNT
                     YMLASQIREAGGEPFILQAIHDDLSLARTSVREAIAAYDIVVTSGGVSVGDFDIMGDLV
                     RQEDVNMLFNKVTMRPGSVTTAAVIDGKLLFALSGNPGACFVGCELFVRPTIQMMVSSA
                     HPYLQTWTAKLGADYMKVNNYTRFVRSSLEIRGGQVYAIPARVDQSSVMVTIKDSDCLI
                     VIPPTTEGLREGEEVRVLVLQGGQVT"
     gene            12285..12833
                     /gene="mobB"
                     /locus_tag="OF859_RS16785"
     CDS             12285..12833
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="mobB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371420.1"
                     /locus_tag="OF859_RS16785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="WP_028541693.1"
                     /transl_table=11
                     /translation="MNTKHPFVCQIVGFKNTGKTTFLGGLIRYVQKSGLRVAVIKHDGH
                     EFEMDHEGTDTFKHRQAGAEGIAIVSAGRTAILEENSQPVTGLIRHFQAYDCVLLEGFK
                     QEDYPKLVMVREQSDAQLTDKLTNVQGVAVWEHQMDWAQGHYSDEMIQIFPAEANGPAG
                     RWLLEQIQKQIEGMRNEQG"
     gene            complement(12838..13938)
                     /gene="xerS"
                     /locus_tag="OF859_RS16790"
     CDS             complement(12838..13938)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene="xerS"
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019687399.1"
                     /locus_tag="OF859_RS16790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosine recombinase XerS"
                     /protein_id="WP_023988943.1"
                     /transl_table=11
                     /translation="MNIQKIIDRRKLDEKMPGLPWYVQQFMDYKLPDLSPSTLLEYVRD
                     YEAFFSWLRAEGLSTGETNAQVTLEELETLHMDSITGFRLFLSTKREGSNSRITISRKL
                     SSLRSLFHYLSQIAEDENFYPLLKRNIMAKVEIKRIHKPKDTAAKLKGKILEEEELLEF
                     IGYIYEGYGQDLADNKQALYSYELNKERDACIASLILNSGLRVSEIVNLNLDDLDINNK
                     LLYVYRKGNNDETFKTPVYFREQSKDDLVLYLSLRHTRYRAPKKEKALFVTRPNGSTEG
                     KRMTKRAIQAMIIKYAKRFGKPYLTVHKLRHSFATDYYLQNDIYKTKEQLGHASTETTE
                     VYAHLTDKTMSQAIERRVETLTDSAD"
     gene            14055..14564
                     /locus_tag="OF859_RS16795"
     CDS             14055..14564
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427739.1"
                     /locus_tag="OF859_RS16795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_264453705.1"
                     /transl_table=11
                     /translation="MGYNIKSELKLSIKSVPESQKDIIVQLMQFYLYDFTAYLRIDVTE
                     KGTFPAYPDLYQYWTSGEQKLPFLIWRQDIPVGFALVDRMSSNREADYYMAEFFVLRPY
                     RHNGVGTWAAHELFGRFNGRWKVTQMSTNRPAQSFWRKVIGSYTKGEYREQTHSVRGNI
                     SQFFNT"
     gene            14849..16465
                     /locus_tag="OF859_RS16800"
     CDS             14849..16465
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010280475.1"
                     /locus_tag="OF859_RS16800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_264454830.1"
                     /transl_table=11
                     /translation="MVAVTLSMVLVLSACSGNSGANSTNTEANAAGGGQAAEGGDLTYA
                     LATSPDSLDPHKSGLAVASRVYRAIFDNLVVKLPDNTIKPWLATEWSVSEDGKSYTFKL
                     RKDVKFHDGTPFNAEAVKFSYDRIIDPQAVVGNAANLLAPYESSQVIDEYTIKLNLKRP
                     SQAFLSNLSVPAVAIVSPAGVKKYGDQFGKHPVGTGPFKFVKWDENAEIKIERNPDYKW
                     APETIENQGAPYLDSVTFKIVPEEATRIGSVQSGQALAAETVPPQNILTLKSDPNFQLL
                     QVNTLGLPYTLFINQKKKPWNELKARQALQYGIDVGTIVKTLYLGTYEQAWSPLTPGIF
                     GYDKSLENGLQPDLNKANQLLDELGWAKGTDGFRVKDGQRLTLHYVDGTPNREKRNDIA
                     AIIQQQLKKIGVDVKIEITKDIATVVYTNGNYDFYGNSQVNVDPNALYAFYHTAATNQR
                     PTLPNFSNPEVDKLLEQGAIEQDDAKREEIYKKVQQLIRDQAVIIPIYVFPYTVGAAKS
                     VQGLKFDLVGYPLFNDVRIQK"
     gene            16517..17443
                     /locus_tag="OF859_RS16805"
     CDS             16517..17443
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010280476.1"
                     /locus_tag="OF859_RS16805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_076265280.1"
                     /transl_table=11
                     /translation="MIRAVAERLVTSLLVILGSCILVFSILYLLPGDPVDSILDPSTAT
                     PEMIANLRHKLGVDQPFHVQFLNYFGNLLQGDFGKSLLNADPVLPKIWVNLPPTLALTL
                     AGSAISVIIGVLLGVLSAIHRDKPIDIIARIVGLFGISMPTFWSGILLLLIFSIHLGWL
                     PAMGSGGWKTLVLPSLTLGIVGAGFIVRMVRNSMLEVINEQFIVTLRSKGLSEKVIMYR
                     HALRNALIPAITMIGMLMGEMLAGAVVSETVFSRQGIGRLIADAIMAKDLPVVQGVVLF
                     SAIMYVIVNLLVDISYTFIDPRVRRSA"
     gene            17474..18370
                     /locus_tag="OF859_RS16810"
     CDS             17474..18370
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014281533.1"
                     /locus_tag="OF859_RS16810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_076265281.1"
                     /transl_table=11
                     /translation="MRETMAAKTIWKERKLRVARQTGRWRLGGVSDGFVYAAGLIIVFV
                     IVCAAFPQWIASYAPTEMLSDHILQGPSASHWFGTDYFGRDVFSLVVHGSRDSLFIGFM
                     SVLVGGLVGGIIGALSGYIGGTVDSILMRFIDILMTIPGILLALAIAAALGPSLFNIVL
                     AVAISAVPGYARVMRGQIMSIKGRSYVIASLSIGVTPFGIFWRHVLPNSLSPLLVMATL
                     GIGSAILAGSGLSFLGLGTVKEIPDWGTVLSQGRGYLTVAWWICTFPGLAITLFVLSVN
                     ILGDKLRDQLDPKKNAN"
     gene            18416..20548
                     /locus_tag="OF859_RS16815"
     CDS             18416..20548
                     /EC_number="7.4.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014281534.1"
                     /locus_tag="OF859_RS16815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="WP_076265282.1"
                     /transl_table=11
                     /translation="MSSLLEIEHLSVDFHTKKGLLQALDNVSLTIRAGETVCLVGESGS
                     GKTITSKAIMRLIDYENGRIAQGQIRLQGIDLTVLSQQELRSLRGKKMAMVFQEPMAAF
                     DPVYTIGYQLIEIIMEHDRKTRKQAWAHAVHLLNRVGIPEPEIRMKQYPGELSGGMLQR
                     AMIAMALSCGPELLIADEPTTALDVTIQSQILQLLQELKTEFNMSILLITHDLGIAAEV
                     ADRIVVMYAGRVVEQAVTEELFELPLHPYTRGLLRSVATLDTDRSSKLFSIPGAIPSLS
                     ALPSGCLFHPRCPHATDQCKNEAPPLATKDEREVACWHSEQLAASDEWHITELSMKGQI
                     TANAVAKATEVKEELTNVSAVDGAKVSSHGVQVKNSPKSNETITETVQNKQDLFRVDGI
                     RKYYPVKKSFPGRTGASIRAVDDVSFSIRQGETFGLVGESGSGKSTLGRLLMQLERPTS
                     GQVWFQDRELTRLGNSELRSVRRDMQMIFQDPYGSLDPRWNVGDIIGEPLAVHEGLYGK
                     AKQERVEELLSAVGLSPSLVTRFPHEFSGGQRQRIGIARAIALQPQFILADEAVSALDV
                     SVQAQIVNLLQDLQRKLDTTYLFIAHGLHIVRHISDRIGVMYLGKLVEIAPSDELFRHP
                     AHPYTRGLVASIPNPNPKNRRELITVQGEIPSPAKPPSGCRFHTRCPLATSRCREEAPE
                     LTAISTGHYAACHYPA"
ORIGIN
        1 tgcccaatac aggtgcctgg acctcaaatc cgtgaaaaac cagttcttct tttaaacggg
       61 cagcggccag aaattcctcg tttccaagtt caggatttgc gccaataaat aacgaaatgt
      121 ccttaaaccg tggggcatgc tgctcgatgg tctgttgaat ggtctgttta aaatccatgc
      181 tgaaaactcc tttatataag ctgtaatgta ggtactgcgt taggtatgct gaaattgtac
      241 tataacattc attgcataat catgcatatt catttataat gacacaatct tatttattat
      301 aaagaattta aggagagaaa aaaagattga aaaaggcata tcgttttacc gccctggttt
      361 tgacggcggt tatcttgctg ttgactggtc ttcccatgct caatgcatac ggaacggaag
      421 caaagccaca gaaaaaactt gtagtgggca tgagtgccga ctttccgccg tatgagtttc
      481 ataaagtcat taacggtaag gataccattg ttgggttcga tgtggatatc gccaaggaaa
      541 tcgccaaaga tttggatgcg gagatggtcc ctgaagacat gagttttgac tctttgctgc
      601 ctgctctgca aagtggtcgt gtagacttgg tactgtccgg tatgacacca acggatgaac
      661 gcagaaagag tattgatttt tcggatgtat actatcgctc caagcaagtc atcatggtac
      721 gcccagagga taaagacaaa tatccgacga tggatgcttt gaaaggcgag aagatcggag
      781 cacaaaaggg aagtattcag gaagagattg ctcaaaaagt gcccaatgcc tctgtaactt
      841 cactggataa aatatctgac ctggtactcc agctgcggac ccagcgtgtg aacgctgtcg
      901 tgatcgaaga tacggttgct aaaggataca cgttagacgg taccgtaacc cttgccaagg
      961 ctgtgcctga ggatgcggga gcagaaacag ctgtaggtat ccgtaaaggg aatgcagaat
     1021 tgcttgcttc tgtaaataaa acgttggctc gcctgaaagc agacgggtcg attgagaagt
     1081 tttccacgga agcgagtgca ctttctgcgg atcgtcaggt ttcttctaat aacattgtag
     1141 atattttttg gaaataccgc agtttatacg ctacgggtat cggctacacc ttgttgctgt
     1201 ctgcgctcgg agtactgttc ggattcatca ttggtctgat catatccttg ctacgtatga
     1261 gtggagtacg catcattgag tggttaggta ccacttatgt agagatactg cgtggcacac
     1321 ctatgctggt gcaactcatg attattcact acggggttgc tttgacgctg ggtgtcaatt
     1381 ttactccact ccagtctggt ataatcacat tgtctctgaa tagctcggca tatctggctg
     1441 aaattttccg tgcaggtatc caggcagtag accgtggaca gatggaggct gcccgttcat
     1501 tgggtatggg acgaggcaaa gctatgcgtc atgtcatttt gccgcaagcg tttaaatcta
     1561 ttttgcctgc tatcggtaat gagtttatta cgatcattaa agaatcatcc attatttcga
     1621 ccattgggat ggtggatatt atgtatcagg cccaggtcat taagaacatt acctacgaag
     1681 gattaagtcc gttcgtaatc gcagccgcta tttattttgt aatgacattc agcttgtcta
     1741 agctgctggg tttatgggaa aggaagttga gagccagtga tcaccgttaa acaactgcgt
     1801 aaatcgttcg gcaagaatga gattttaaaa ggcattgata tagatatcgc caaaggtgaa
     1861 gtcgtcgtca tcatcggtcc cagcggttcg gggaagagta cgtttttacg ttgcatgaat
     1921 ctgctagaac agcctacgga cggggagatt ttgtttgagg gcgagccgat tacagctcgt
     1981 ggtcataata ttaatgtaac ccgggagaag atggggatgg tgttccagca ttttaatctg
     2041 ttcccgcata aaacagtgtt gcagaatctg acgcttgcac caacgcaggt tagaagacag
     2101 tcagggaagg aagcggaaaa aattgcgcta gaactcctgc gtaccgtagg gcttgaggat
     2161 aagaagaata cctatccgaa ccagctatcc ggtggtcaga agcaacgtat tgcgattgcg
     2221 cgtgctttgg ccatgcagcc gcacgtaatg ctgttcgatg agccgacttc tgcattggac
     2281 cctgaaatgg ttggagaggt tctggatgta atgaagaagc tcgccgaagg cggcatgacc
     2341 atggtaatcg tgacgcatga aatgggcttt gcccgcgagg taggcgatcg aatcatcttt
     2401 atggataacg gtcaaattgt ggaacaaggt acaccagagc aggtatttgg tactccaagc
     2461 catgatcgca cccgtgattt tcttgccaaa gtattgtaag aaagtgctga tatgagctat
     2521 aaaaaagccc tccgtttgac ggagggcttt ttcttttttt gtcaccattt caccatattt
     2581 tcgtaacaaa tatcgatttc ttggtgacaa aattgtaacg agtatagtat gatgttcaag
     2641 gttcccaaca ttttcatgcg gataaggtta caaaattgtg atattatgca gtaagccaaa
     2701 acttaccggg acagcatgcg gttatgaaaa acgctgaatg ctgggcccaa actatgggaa
     2761 gtgcggggga cgtaacaacg gcagtctttc cgatacgtca taagacgata tggaatatgc
     2821 ctaggggtga attgcacaag catagggctt ctcctgagtc cgaatccgac agctaacttc
     2881 gcaggcataa cagaggaggt acatatcttt gaaacatcta aaacatattg gaaaaaccat
     2941 gaaatttgcg gtgcttgccg cagccattgc agggctggca cagacagctg gagtagcgga
     3001 tgctgcttcg cttcatactg ccaaagatgg cgataccttc tttttgcttg ctcaacgtta
     3061 tggagtatca gtggacgagc tgacgaaggc gaacccaaac attgcctcta acaatatata
     3121 tgcaggtctg caaattaagg tacctggtga aaaaagtgtg aatgcagctt cggattcgaa
     3181 gcctcagctt cttacggaga aagcaccagc gaatgagggg ccagcgattg aagcgtgggg
     3241 caaaacattt aactatagca aaatagtcga cgttaaggct actgcgtatt ctgccgcagc
     3301 cgatgagaat ggtaaatggg gagcagtgga ctactacggc aatccgctta aactaggtac
     3361 aattgcggta gacccgaacg tcattccgat gggcacgaaa gtgctggtta caggctattc
     3421 ccacccaggt ttgccggatc attcttttgt agctgtcgct cgcgatcagg gcagcgccat
     3481 tacaggaaaa cggattgata tctttattcc tggcaacaaa tcatttgtga acgactttgg
     3541 atttcaaaat gtgaagctgt acgttattga taaatagcat tatacgtata tatggtttaa
     3601 ttaaacataa tatatattat gtaaacttaa tgcctgtatc ctaccgcata taactaggtc
     3661 agactcttat caggtcctat ccataaaaaa ggctgtcttg acgagcagaa aacttctgct
     3721 ggtaagacag cctttttacg ttgctttagc ttgtagctca atcataaaca tatggttatt
     3781 tctgttccga tgtgtggagt agccggggga ctgtgacaaa tttgtagccc ttagctttta
     3841 gagagtgaat tagacccggc agagcttgaa cagtgccttg caagttggaa ctttgacctc
     3901 cacctgcgtg cattaaaata atagagccag gcccagtagc tgggatcaca ttgcgctgaa
     3961 tttgtgtttt acttagtccc ttccagtcga gagagtctac attccaattg acaatcatgt
     4021 agccatgacg acgtgcccac tggatttgag gctccgtgat ttcaccgtag ggtggacgaa
     4081 tcaacttggg gcgaaaacct gcgctggctt gtaaaatacg ttctgttttt gtaatctggt
     4141 tgcgaaagcg ttctggtgtg gccttcctaa aatcaggatg agtataggaa tggtttccta
     4201 tagcatggcc ttcacggata atacggcgta tgatccccgg atgcttttcc gcacggtgac
     4261 cgacgatgaa aaaggtagct ttgatgccat tggcgtgtaa tacgtccaaa acctgcggcg
     4321 tatacctaga atcgggcaca tcatcaaagg ttagggcaat ttggcgggtg tgtgggccgc
     4381 acattttaaa aatgtccgca tgtttttttc gcagcattgc taatgtagga gttgctcgat
     4441 ctatgctctg ttgtacagaa gaagcaacag ttgcttcctt gggatggggc gttccgatgt
     4501 tgggaggcgc atccgcgtga acgggtaaac ttgaaaatgc tagtaacagt gccaagcctg
     4561 gcaacactcc cctgtacggc atatgtatcc cccctttccg tgcagtgata cctagtggtg
     4621 ctctcgacta ttatgtacct gtcctattaa aaatatgctg gttaccaagt tcggctcata
     4681 aacgactgga aagaagtcca cgatgaaacg attatcaatg aagatgatgg agctaaacgt
     4741 acatattctc ttaaacatga ccgaaaacag gagcattttc gcaagtttta gccttacaac
     4801 gaattcggta taccgtgaca gctggtgtat aatggggatg caattcataa ttgtacagac
     4861 atggaattga aggaaggatg gataaaagtg accgacttgt ttactcctta tcaattaaag
     4921 gggctttctt taaaaaatcg gattgtcatg cccccgatgt gccaatacag cgtggaggcc
     4981 aaggacggaa atccaacgga ttggcatcat gtccattatg tgagccgggc agtaggaggc
     5041 actggactta ttattgtgga aatgacagcg gtccatccag atggacgtat tacagatcgt
     5101 gatttgggta tttggagtga cgaacatatt cctgcatatc gtaagattgt agaggaagtt
     5161 cacaagtatg gtgccaaaat tggcattcaa ctaggccacg ctggacgcaa ggctgaagat
     5221 gctgagcaac ctgtgggtcc ttcctcgatt ccttttagcg aacgctttaa agagccgcac
     5281 gccttaaaga cagctgaagt cagggaactg gttcaggcat acaaagaagg cgcgcgccgc
     5341 gcggtggaag caggttttga cacggtcgag atacatggcg ctcacggcta tctgatccat
     5401 caatttcatt cgcctttaac aaatgccaga gaagatgaat atgggcagga tttgtcactg
     5461 ttcggtgttg aggtcataca tgctgttaaa gaggttcttc ctgctgatat gcctgtgctt
     5521 atgcggattt ctgccaaaga atacgtcgag gatggatata atgtggaata cataacaggc
     5581 gtaggggaac gatatcgtga tgcgggtgtg gacattttcc atatctcttc tggtggtgag
     5641 ggtccgattg gttctggcgg aggcccgtct gcgcgtgccg gctatcaggt ggatttggct
     5701 cataccatcc gtgaaaagct gaatgtacct gtaattgctg ttggcttact ggatgattat
     5761 gaggacgccc gtcgggttgt tcagcagaaa gaagctgatc tggtagcaat aggccgtgcc
     5821 atgctgcgtg atccctattg ggcgttgcat gcatcgcggg agctaaaagt acaggccgac
     5881 atcccagagc cttatttgcg cggcttttag atatttttga aaccctcttt gcaaagcttg
     5941 cgtaaacatg tgtacagagc ttaaaattta agcattcaac tctaggagga acttcacatg
     6001 tctattttca aacgattaag agatcttacg atgtccaaca ttaacgccat tattgacaag
     6061 gcagaagatc caattaaaat gacggatcaa tacattcgtg atatgcaaga ggacctggaa
     6121 gatgcagaga aagcggtagc cgctcaaatt gctattgaaa agagattcaa acagcaatac
     6181 gaagaacagg ctgctttggt aaagaaacgc gaagaacagg cacataccgc tgcaaaagca
     6241 caaaatgtag atctggctcg tcgcgcgctg gaagaaaaga aatctgctga acaaaaaatg
     6301 aatgagttca aagctggtta cgaacagaac aaagctgcag ccgataacct gcgtggcaag
     6361 ctggatgaaa tgcgcagaca gctgacagaa atgaaaaaca agcgcgagac actggttgct
     6421 cgttataatg cagctaaagc gcaaactgaa attaacaaag ctatgaacgg ttttagctct
     6481 gatacggcaa ctgccggatt gaagcgtatg gaagaaaaaa tgctgcaagc agaagcacgt
     6541 gccgaagcga gcaacgaaat gtcttctaag gaaaaatcgt tggatgagga gttcaaggag
     6601 ctggataaga aaagcgccgt ggacgatgag cttgccgctt tgttgaagca atacgaaaat
     6661 aaataagaac attttagcag tgccgccaag ggtgattgct caggaagcga aggagaaacg
     6721 ttttctcctt cgcttttccc tgcctggagg cgtaaaacat tatatgaagg tcaagaagat
     6781 gtggaggatg gtatgaaatg cattttttag aaacgatgaa agcaatgctt gtatggactg
     6841 gtgcgggggc aattttgatc ttcgcattaa tgtatgtcga ctctttattt acgaagtata
     6901 aggattttgc cgaagtgaag gctggaaata tggccgtaac ggtacgaatg attatgaagt
     6961 tagttgcaca aggctatatc ttgtcaggct ctatcgctac agctaataat ttgctcgaag
     7021 cgcttgtgta ttctgtgatc gcctttgtca tcctgcttgt tttggaagtt attgtacgtc
     7081 tgctgttgcg gtactgggct cagtttgatc tggataaagg tacacaggaa ggtaaaattg
     7141 gtttcggtct gttttcagga gcgctgcatc tggttggcgc cttgatcatt acagcatgct
     7201 tctaggctaa gaaaggcagg aatataacca tgggtgtgtg gaaacgaatt tcaaatctat
     7261 ttgctaagcc ggagccgcca aaagcagaga aaagcatgct tcacttaaat ccaggtgata
     7321 tctgtgaagt gtcgcttgtc acctatgaag tggtaggtcg tgtacataat cgtgcccgga
     7381 atgccgttgt tttgacgctt caggatggta atcaagtcag ttatcttcat attgaggaac
     7441 gggaaacact gcaattcgga ctatatcagg ccatcgacgg cagacttgac aaccctgagg
     7501 aagtgccgac cattttagag ttggatgata caacgtatca tttggaggag cagtattctg
     7561 ggcatgttac cgtcatgggc cgtgctcctt tccgacaggg tggagagcag catgtgtggc
     7621 agtaccagtc tgatgattac catctgttgc gagtagagtg gcaggacggt cgctttatgc
     7681 tttatgaagg agaagaagtg attaccggag acgtcaaggt tattcgggca agctaggaga
     7741 gggttacaca tgagcaaacg cacctggcag tatgcattaa aggtcattgt ggcgctgagc
     7801 ttgttcgttt ccgtgttaag cggctgcggc gcgccaagtg taaaagatac gtatccgttg
     7861 gaatcggtta gtggcagcgg aaactcgacc tcgtatgtat accgggcagc tggcaagaca
     7921 gtcccggaag tagcggagga attgaaagaa cagcgtacac cggaacaaat gtcaccgcag
     7981 agcaatgagc ggatgtttct ggtatatagc gatgagtggt accatttgca gcaagatcca
     8041 gctaagaagg aagatacact cattgaaatt gacagtaaaa agtatgtcga acaaaattac
     8101 agttcaagct ttctaaaagg atacttaacc gcaactgtac tggatgctct gtttgattca
     8161 ttgcgtggtt caggctccta tcgaggctac tccagcagag atgtataccg accttctcag
     8221 ggccaatatc gtgctcctac ggtgcaggag aaaaaggcga ttccgccgat tacggtggag
     8281 cggaaaggtt cggttacccg tagaggaaag aactcggatt ctagcgttgg atcaagcgga
     8341 agtttgttcg acagagggtc cagcagttca ccgagcagag gctcgatttc acgtgaccgg
     8401 agcgacagtg gcggttccag catatttgat tcgccgcgta aatcttatag taagcccaaa
     8461 acacgtagcg gttcaggtaa aatcagccga cgaagtcgac gataatgggt atcgtcaatt
     8521 tatttgaaaa caaaagattc ttggaactgt ggtactgatg cacagttcct ttttttattt
     8581 ttagagatga cgttggtgat catctagcgg cacagccaaa cctacacttt tatggatata
     8641 ataatgtaga gataatcaaa actttgtttg attgaaggga ttgaaaatta aatggtacta
     8701 tctatttctt ggccagatct ttcacaaaga ccatttaatc taatggtgga acgaaaaatg
     8761 gagtgttctc cgaatgtcct gtatcaggct tggacgaagc ggtttgacag ttggtttgca
     8821 gccccaggat cagtattaat ggaggctgaa gtgaacatga ccttcttttt cgaaacgcat
     8881 tttgagggga agcgtcatcc acattacgga agatttctaa gacttgagca aaaccgactg
     8941 atcgagctga cttggattac tggcgaaggc ggtaccaagg gagctgaaac agttctcact
     9001 gttgagctta aacctcgcgg taatggcacg catctttact taacgcatgc aggtttacca
     9061 gacgagaatt caagaaacca acatgagcag gcttggccgc ttgtacttga gcagctcgac
     9121 aaaaggatga tgccagatag ataattcaga aggttccagg ctaaaactgc aacaagagga
     9181 cgattttaaa atcgttcttt ttatattttt tgatgacaaa aataaatatt taccttacat
     9241 aaaaacaaat attaccagtt tactagatta tttcattgcc acatctataa gtaaaatata
     9301 caattacaac aggcgaaata agaggatggt gtatctgtgt tatctgcttt tttatatata
     9361 ttacttggtg tattcgatgc tttggccgct gttattttgg tcttaaagct ttatatgctt
     9421 cccgtgaggg aatatcgtag aaaaatatta ttttatgcaa ttggcatagc tttgttttcc
     9481 tttctaatga gggaagttat aggcttgcct aaattagatt tgccgcttca gtatttgtta
     9541 atggttatct tttttagatt cggtttaggg atcaaaaccc atctagcagc tttttctgct
     9601 ggttctggtc taacggccta cattaattta caactttttg tatttctgtt tgcgtatttt
     9661 tttggagtag cagaaccagg tgctattaat gatacttctg gctcttctat ttacgttatt
     9721 cagttaactt ctattattat tgcgtgcttt atttcttata taatgggaaa atataacttt
     9781 ggtttctcgt ttataattca gcctccacat gattttttaa gagctgaaaa ttacttatca
     9841 tccctaaata aaatgttgat tctaggtgct ctaatatcag ctgtcaccat ttttattact
     9901 ttgtatatgc tctatagctc aaataccata ggattactat ccatttcatt gcttactttc
     9961 ggcgtgtcgt atttcttttc agagagagga gattatgagg atgctagaag cgctatcacg
    10021 gtacatcgca acggaaataa aaaaagctga tcctgatggt ccaacaagtg tagaagtgat
    10081 ggaatatgcg cttggtataa aaattaccga agtgtcttcg atactaatgg ttgcgattat
    10141 agcttggatg actgggcatt tttttgggtc gttattagct ctagtaacta tcatgtttgt
    10201 aagaagattt tcaggagggg cacacttcag taatcttaca ttttgtgtct gttttacaac
    10261 ggcaatatgt gtaactatac ctctcgtctc tttaaattta tcaacgattt tgattattaa
    10321 tgcttgttca gtattagtgt ttttagttta tgcacccaat cattttattt atattcataa
    10381 gaccaataac cacaaatatt ataaaacggt atgtgttttg atttgtgcgg tgaatttttt
    10441 tgtacaatcc cacataatat gcttatcttt agctattcaa gcattcagta ttcttccttt
    10501 atggaaagga ggtgaacgaa aatggataag aaattggcga gagctttaaa tttaagactg
    10561 ggaaaatacg ctaacgaatc taccaaaaac gaaaaaacag tatttggcgc taaaccgata
    10621 ccggcagagc tcaagaaaaa agaaaagaac tgattatgta ccgcgttact ctagacattg
    10681 ttcttatacg atcggggtaa ctgcacaggc ttgtaaggaa gcttttcagc tgtgagatcg
    10741 agtctagcgc atttgaaggc ctggtacgat tcgaagcttc acttgctcta tttctcataa
    10801 taagcttgaa gcacttataa agttatggaa atgacccgtg gaattcacgg gttattttat
    10861 tgccaacata cttatatagt aagcccaaaa cacgcaacag cacggggaaa agcagccgag
    10921 tttgacgttc taaactccgc ccggatttgc cagataacgg ttttagcgtt ataacagaaa
    10981 gagggcattt tagaagaacg gagtgagatt atgaatcata catcattaaa cgcagaaaaa
    11041 ttccagcgta aagcagttca ggtggaagag gcacaaagca ggatagctag ctatgttaaa
    11101 cagggtgaaa gggaagacgt agagctggag caggcgcatg gacgttattt ggcgatggat
    11161 ttgaccgcac cacacccgta tccccgtttt cgtcggtcag gtatggacgg ttatgcgatc
    11221 ctaggctcgg acaccgaagt gtgctcatcc ggtcaggaaa tctggctaca tgtgattgat
    11281 gaaattccat gtggcaccgt atcggacaag cgggtggaga ctggaatggc tgcccgcatc
    11341 atgacaggag cgcaattacc tgaaggagcg gacacggttg tcatgctgga agcgacacag
    11401 ctgcgtgagg aaaacggaca gacatatgtc ggcttgaaga agcgtataga agttggcaaa
    11461 aatgtgacac agattggtca tgagattcag gaaggtcggc ttttgcttag taagggaacc
    11521 tgcctgggag cagggcacat ctcggtactg gctacttttg gagtacaccg ggtacctgtt
    11581 tacaggaagc caaaggtggc cgttttttct acaggatcgg aattacttgc agtggatgag
    11641 ccgttacaac cggggaaaat tcgaaacagt aatacatata tgttggcttc tcaaattaga
    11701 gaggcaggag gagagccgtt tattttacaa gccattcatg atgatttgag ccttgcccgt
    11761 acttctgtac gtgaagcgat agctgcctat gatatcgtgg tcacgagtgg aggagtatca
    11821 gtgggggatt ttgatattat gggtgatctg gtacgacagg aagatgtgaa tatgctgttc
    11881 aacaaggtta cgatgcgtcc aggaagtgtg accacagccg cagtgattga cggcaagctg
    11941 ttatttgcgc tttcaggcaa ccccggtgcg tgctttgtag gctgtgagct gtttgtacgg
    12001 ccgacgatcc aaatgatggt atcttcggca catccatatt tacaaacctg gacggcgaag
    12061 ttaggcgcag attatatgaa ggtaaacaac tatacacgct ttgtacgcag ctctctggag
    12121 atacgtggtg gacaagtata cgcgattcct gcgcgagtag atcaatccag tgtcatggtg
    12181 accattaagg acagcgactg tctgatcgtg attcctccca caacagaagg attacgcgaa
    12241 ggtgaagagg tgcgtgtact ggtgttacaa ggtggacagg tgacgtgaat acgaaacatc
    12301 catttgtatg tcaaatcgtc ggattcaaaa atacgggaaa aacgaccttt ctcggaggat
    12361 tgattcgtta tgtgcagaag tcaggtctac gcgtagcagt gattaagcat gatggacatg
    12421 aatttgaaat ggatcatgag ggtacagata cgttcaagca ccgacaggcg ggtgctgaag
    12481 gcatagctat tgtttcggct ggaagaacag ccattttaga ggagaatagt cagcctgtca
    12541 ccggactgat ccggcatttt caggcctatg attgtgtgtt gctagaaggc ttcaagcaag
    12601 aggattatcc gaagctggtc atggtgcggg aacaatcgga tgctcagctt accgataagc
    12661 tgacaaatgt acagggagta gcggtttggg agcatcaaat ggattgggct caaggtcact
    12721 actcagatga aatgatacag atatttcctg ccgaggccaa cggacccgca ggccgctggc
    12781 tactcgaaca gattcaaaag cagatagaag gaatgaggaa tgagcagggg tgagacatca
    12841 atcggctgag tcggttagag tctctacccg ccgttcgatc gcctgagaca tggttttgtc
    12901 agtcaggtga gcatacactt ctgttgtttc tgtcgaagcg tgccccagct gttcctttgt
    12961 tttgtaaata tcattttgta aataatagtc agtagcaaag gaatgacgaa gcttatgcac
    13021 ggtaaggtaa ggcttgccga accgtttggc gtacttaatg atcattgcct gaatcgctct
    13081 tttggtcatt cgtttgcctt ctgtactgcc gttaggacgt gtgacaaaga gagccttttc
    13141 tttttttgga gcgcggtaac gggtatgtct cagggacaaa taaagtacga gatcatcttt
    13201 ggattgctcg cggaaataca ccggcgtttt aaaggtttcg tcgttattgc ctttgcggta
    13261 cacatataat agtttattgt ttatgtctaa atcgtccaga ttcagattga cgatttcaga
    13321 tacgcgcagg cctgagttca gaatgaggct ggcgatgcag gcatcccgtt ccttatttag
    13381 ttcataggag tataaagcct gcttgttatc ggccaaatct tgaccatagc cttcataaat
    13441 ataaccgatg aattcaagca gttcttcctc ttccagtatt ttacctttaa gcttagccgc
    13501 cgtatccttg ggtttatgta tacgcttgat ttcgacctta gccataatgt tgcgtttgag
    13561 caacggataa aaattttcat cctcagcgat ctgacttaaa taatgaaaaa gcgaacgcag
    13621 agacgatagc ttacgtgaaa tggtaatacg ggagttggag ccttcgcgct tagtagacag
    13681 gaataatcga aagcctgtaa tactgtccat atgaagtgtc tccaactctt ccagtgtaac
    13741 ttgggcattc gtttctccgg tggacaagcc ttccgcgcga agccatgaaa agaaagcttc
    13801 gtaatcccgc acatattcta gtaatgtgga aggggacagg tcgggcagct tataatccat
    13861 aaattgctgc acgtaccatg gtaatcccgg cattttttca tctagtttgc gccggtcgat
    13921 gatcttttgt atattcattg agttccacct cgtccggtca taatatatat gtattttagc
    13981 atattttgaa cagcactgga tgggatgtaa ttcgaagtta aagaacagat tgaaccgcca
    14041 agagaggtga aagtatgggg tataatatca aatcggaact gaagctgtct attaagagtg
    14101 taccggagtc gcaaaaggac attattgtac agctcatgca attttattta tatgatttta
    14161 cagcctatct tcgaattgat gtcactgaga aggggacatt cccggcttat ccagacttgt
    14221 atcaatattg gacgagcggt gaacagaagc taccttttct gatttggaga caggatattc
    14281 ctgtgggttt tgcactcgtt gaccgaatgt ccagcaatcg agaagctgac tactacatgg
    14341 ctgagttctt tgtacttcgt ccttatcggc ataatggggt tgggacttgg gcggctcatg
    14401 agctgtttgg acgttttaac ggacgttgga aggtgaccca aatgagcacg aataggccgg
    14461 cacagtcctt ttggcgtaag gtgattggaa gctatacgaa aggtgagtac agggaacaga
    14521 cacattcggt aagagggaat atcagtcagt ttttcaatac ctgaaaaatt cgaaatagaa
    14581 agtaagtaat gaaaaagagt cgaggagagt atcctatcgg ctcttttttg ttgtcaattc
    14641 aagtcttcta tccatctata gagcattcca attagaacct gcattgacac tataaaaacg
    14701 caggtataca gttattaaca taattcatat atatctcatt ggaattatca acaattaaac
    14761 atcggctcca aaaatgcaat gtaatcataa catcacccat cagatcggag agtgttttta
    14821 ggtgaaacga acaagtcgat ttgcaaaaat ggtagctgta accctgtcga tggtgctggt
    14881 cttatcggca tgctcgggta atagcggggc caattctacg aatactgagg cgaatgcagc
    14941 aggaggcggg caagctgcag aaggtggaga tcttacctat gcactggcaa catcgccgga
    15001 ttcactggac ccgcataaga gtggattggc agtagcatct cgggtatatc gtgcgatatt
    15061 cgataacttg gtggtaaagc taccggacaa tacgattaag ccttggctgg caaccgaatg
    15121 gagtgtttcc gaggatggca aaagctatac attcaagctg cgcaaggatg ttaagttcca
    15181 tgacggaacc ccgttcaatg cggaagccgt taaatttagc tatgatcgga ttattgatcc
    15241 gcaagccgta gtaggtaatg ccgctaactt gctggctccc tatgaatcct cacaggtgat
    15301 tgacgaatac acgattaaat tgaatctgaa acgaccatca caggcatttt tgagcaattt
    15361 aagtgttccg gctgtagcca ttgtttcgcc agcaggagtt aaaaaatatg gagatcaatt
    15421 cggtaagcat ccagtgggta caggcccctt taagtttgta aaatgggacg aaaatgcaga
    15481 aatcaaaatc gaacgtaacc cggattacaa atgggcacca gaaactattg agaatcaggg
    15541 ggcaccgtat ttggacagcg tgacctttaa aattgttccg gaggaggcga cccggatcgg
    15601 cagtgtgcag agtgggcagg ctttggctgc tgaaactgtc ccaccgcaga acattttaac
    15661 gttgaagagt gaccctaatt tccaattgtt gcaggtcaat accctaggat tgccatatac
    15721 gctgttcatt aaccaaaaga agaaaccgtg gaatgaatta aaggcgaggc aggcattgca
    15781 atatggtatt gatgtgggga cgatcgtcaa aacgctgtat ctaggaactt atgaacaggc
    15841 ttggtcgcca ctcactccgg gtatttttgg atatgataaa tcactggaaa acggcttgca
    15901 gcctgatctt aacaaggcca atcagttact ggatgagttg gggtgggcta agggaacgga
    15961 tggttttcgg gtgaaggatg gacaacgtct tacgctgcat tatgtagacg gcactccgaa
    16021 ccgtgaaaaa cggaacgaca ttgcagccat tattcagcag cagctgaaga aaatcggtgt
    16081 tgatgtgaag attgaaatta ccaaggatat tgcaacagtt gtatatacga acggaaacta
    16141 tgatttctac ggaaatagcc aggtcaatgt ggacccgaac gctttatatg ctttttacca
    16201 cacagcggca acaaatcagc ggcctacact gcctaacttc tccaatccag aggtcgacaa
    16261 gctgttggag cagggagcta ttgaacagga cgatgccaag cgggaggaga tttataaaaa
    16321 ggtgcaacag ctaatacgtg atcaggccgt catcattccg atttatgttt tcccttatac
    16381 ggttggagca gccaagtcag tgcagggtct caaattcgat ttagtgggtt atccgctctt
    16441 taacgatgtg cgtattcaaa aatagtattg ctaagtaatt tctggggacc atccagtaag
    16501 ggaaggagtg tgggctatga tcagagctgt tgcagaaaga ctggttactt ctttgttggt
    16561 cattctgggt tcctgtattt tggtattcag cattttgtat ctgctcccgg gggacccggt
    16621 agattcgatt cttgaccctt caacggccac gccagagatg atcgccaatt tgcgtcataa
    16681 gctgggagtg gatcagcctt ttcatgttca gtttttgaac tatttcggaa atttgctaca
    16741 aggtgatttt ggaaaatcac tgctcaatgc tgatccggtg ctgcctaaaa tatgggtcaa
    16801 tctcccgcct acactggcgc tgacgcttgc cggttctgct atttcggtca ttatcggtgt
    16861 cctgctcgga gtgctgtcgg ccattcatcg ggataagccg attgatatca tcgcacgaat
    16921 cgttggattg ttcggcattt ctatgcccac attctggtca ggcattctgc tgttgcttat
    16981 tttctccatt cacttgggat ggctgcctgc tatgggctcg ggcggttgga aaactcttgt
    17041 gcttccgtct ctcactttgg gcattgtcgg tgcagggttc attgtcagaa tggtgcgtaa
    17101 cagtatgctg gaagtcatta atgagcagtt catcgtaacg ctccgttcca agggtttgtc
    17161 tgagaaggtt attatgtatc gccatgcgct acgcaatgcg ttgattccag cgataacgat
    17221 gatcgggatg ctaatgggag aaatgctggc cggagcagtt gtgagtgaga cggtattttc
    17281 acggcaaggc attgggcgtt taattgcgga cgcaattatg gctaaagact taccagttgt
    17341 gcagggagtt gtattgttct ctgccatcat gtatgtgatc gtaaatctac tggtggatat
    17401 atcgtatacg ttcattgatc caagggttag acgctcggcg taagccggaa ggattcaggg
    17461 aggaggaagt cggttgagag aaacaatggc tgccaaaaca atttggaagg aaagaaagct
    17521 gcgggtagct cggcaaactg gaaggtggcg gctcggtgga gtgtcggatg ggttcgtata
    17581 tgcggcggga ctgattattg tgttcgtaat cgtctgtgcg gcgtttccac aatggattgc
    17641 ttcttatgca cccacagaaa tgttaagcga ccatatttta caaggcccaa gtgcttctca
    17701 ctggttcgga acggactatt ttgggcggga tgtattcagt ctggttgttc acggaagtcg
    17761 ggattctctg tttattggct tcatgtcggt actcgtcggc ggtctggtgg gtggaattat
    17821 tggtgcgctc tcaggttaca ttggcggtac agtggattcg atactgatgc gatttattga
    17881 tattttgatg actattcccg gaattctgct ggctttggcg attgcggcgg ctcttggccc
    17941 aagcttgttc aatattgtgc tggcggtagc catatctgct gtccccggtt atgcaagagt
    18001 tatgcgaggc caaattatga gtataaaagg acgttcttac gtcattgctt cgctttccat
    18061 cggagttaca cctttcggca tcttttggcg tcatgtgctt cctaattcct tgtccccttt
    18121 gctcgtgatg gcgacgcttg gcatcggtag cgctattttg gccggatcgg gattaagctt
    18181 tctgggactt ggcacggtaa aggaaattcc agattgggga acagtattgt ctcaaggacg
    18241 aggatatttg acagtagctt ggtggatatg tacctttcct ggcctagcca ttacgttgtt
    18301 tgtgttgtca gtcaatattt tgggcgacaa gctgagagac cagttggacc cgaaaaagaa
    18361 cgcaaactag catcaggaag cctattctta agtgctatag aaggagggag ttcgtttgtc
    18421 atcattgctg gagattgaac atttgtcggt cgattttcac actaaaaaag gtttgctgca
    18481 agcactcgac aacgtatcac tgacgatcag ggcgggagaa acggtctgcc tcgtcggtga
    18541 atctggcagc ggaaaaacga ttacctccaa ggcgattatg cggctaatcg attatgagaa
    18601 cggacgaatt gcccaaggac aaatacggtt gcagggcata gatttgaccg ttttgtcaca
    18661 gcaggaatta cgctcacttc gtggtaaaaa gatggcgatg gtatttcagg agccgatggc
    18721 ggcgtttgat ccggtgtaca ctatcgggta tcagctgata gaaatcatca tggagcatga
    18781 ccggaagaca cgaaagcaag catgggctca tgcggttcat ttgctgaaca gggtagggat
    18841 tcctgaaccg gaaattcgta tgaagcagta ccccggagag ctgtccggtg ggatgctgca
    18901 acgggcgatg attgcaatgg cactttcatg tggccctgag ctgctaatag cggatgaacc
    18961 aacaacggcg ctggatgtaa cgattcagtc acaaattttg caattgcttc aggaattaaa
    19021 gacagaattc aacatgtcga ttctgttgat tacgcatgat ttgggtattg ccgcagaggt
    19081 tgcggatcga attgttgtga tgtatgccgg tcgagttgtg gagcaagcag taacggaaga
    19141 actattcgag ctgccattgc acccttacac tagagggtta cttcgttcgg tggcaacact
    19201 ggatacagat cgcagcagca agctgttttc gatcccgggg gcaattccga gcctgagtgc
    19261 attgccttcc ggctgcttgt ttcacccgcg ttgcccgcat gcgacagatc aatgcaaaaa
    19321 cgaagcgcca ccgctggcaa ccaaggatga acgcgaggta gcttgctggc attcggagca
    19381 attggctgcc tccgacgagt ggcatattac agagctatcg atgaaagggc agatcacggc
    19441 aaatgctgtt gcaaaggcaa ccgaagtaaa ggaagaattg acgaacgtat ctgctgttga
    19501 tggggctaag gtgagcagtc atggcgtaca ggtaaagaac tcgcctaaat ccaatgagac
    19561 tatcacggaa accgtccaga acaagcagga cttgtttaga gtggatggaa ttcgcaagta
    19621 ttatccggtg aaaaaaagct ttcccggtcg gacgggtgct tcgatccggg cggtggatga
    19681 tgtatcgttc tcaatccggc agggcgaaac ctttggattg gtcggagaat ccggcagcgg
    19741 taagtctact ttaggccggc tgctgatgca gctggaacgt ccgacctcag ggcaggtatg
    19801 gttccaggat cgggagctga cacgtttagg aaattctgag ttgcgatccg ttcgccgtga
    19861 tatgcagatg atttttcaag acccctacgg atcacttgat ccacggtgga atgtgggaga
    19921 tatcataggg gagccgcttg cggttcatga agggttgtat ggcaaggcaa agcaggaacg
    19981 ggtggaagaa ctcctgagcg ctgttggatt atcaccttcg ctggttacgc ggtttccaca
    20041 tgaattttcg ggaggacagc ggcagcgaat cgggatagcc cgtgccattg ctctgcaacc
    20101 gcagtttatt ttggcggatg aggcagtgtc ggctttggat gtttccgttc aggcgcaaat
    20161 tgtcaatctg cttcaggact tacagcgtaa gctggataca acctatttgt ttattgcaca
    20221 cggattgcac attgtccgcc atatttcaga tcggataggg gttatgtact tggggaaact
    20281 tgtagaaatt gcgccaagtg acgagttgtt caggcatcct gcccatccgt atacccgggg
    20341 gcttgttgcc tcgataccta acccaaatcc gaaaaaccgt cgggagctaa ttacggtaca
    20401 aggtgagatt ccttcgcctg cgaagccgcc atccggctgt cgttttcata cccgctgtcc
    20461 actagcgacc tcgcgttgtc gtgaggaagc acctgagctg acagcgatta gcacaggaca
    20521 ttatgccgct tgtcattacc cggcctagg
//
