LOCUS       NZ_CP109848            22388 bp    DNA     circular CON 22-NOV-2023
DEFINITION  Paenibacillus polymyxa strain K16 chromosome.
ACCESSION   NZ_CP109848
VERSION     NZ_CP109848.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5978518)
  AUTHORS   Manfredini,A., Vitali,F., Sas,L., Trzcinski,P. and Canfora,L.
  TITLE     Genome sequence of the Paenibacillus polymyxa K16 strain isolated
            from soil of tomato roots
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5978518)
  AUTHORS   Manfredini,A., Vitali,F., Sas,L., Trzcinski,P. and Canfora,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-OCT-2022) Research Centre for Agriculture and
            Environment, CREA - Council for Agricultural Research and Analysis
            of the Agricultural Economy, Via della Navicella 2/4, Rome 00184,
            Italy
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2022
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 270.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/22/2023 06:01:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,334
            CDSs (total)                      :: 5,275
            Genes (coding)                    :: 5,199
            CDSs (with protein)               :: 5,199
            Genes (RNA)                       :: 59
            rRNAs                             :: 3 (5S)
            complete rRNAs                    :: 3 (5S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 33 of 76
            Pseudo Genes (incomplete)         :: 52 of 76
            Pseudo Genes (internal stop)      :: 19 of 76
            Pseudo Genes (multiple problems)  :: 22 of 76
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:36:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2668887
            Orig. end                         :: 2691275
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP109848.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Strain stored in SYMBIOBANK
            culture collection of the National Institute of Horticultural
            Research in Skierniewice (PL).
FEATURES             Location/Qualifiers
     region          1..22388
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="5"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..22388
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22388
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12388](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12388
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            66..725
                     /locus_tag="OF859_RS11920"
     CDS             66..725
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688169.1"
                     /locus_tag="OF859_RS11920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2625 domain-containing protein"
                     /protein_id="WP_160789870.1"
                     /transl_table=11
                     /translation="MHTLTVEELVDKDNHAWEEVRNILKEGRNSHHIVSAESESATGNT
                     LYRLQVSTKSYLGTVAYETGGIVFDYGWITLLGAGGSGIFGSLTSWNGLQEPESVPALE
                     GMLMVAYDAAGGFFGLDIGKFGRSGHIYYFAPDALEWESTELAYSGFLSWLAEGDLGLF
                     YQTFRWNGWQKDMEQLQPGEVFAYYPPLWTQEGGGETSSKSPIDITNAWQVALDKE"
     gene            782..1318
                     /locus_tag="OF859_RS11925"
     CDS             782..1318
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013311300.1"
                     /locus_tag="OF859_RS11925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_023989666.1"
                     /transl_table=11
                     /translation="MWSIQFEQPFVISQEATDEQIANFLKTWNIKLSEQEIHEIKQRQV
                     NPFPKSSPFYDQYKPLDPVGWHLPQGQFPDSYMEFLKYSNGGEFQNGERYFQFFNTEDL
                     REMNLAYELPEYMPGAVSFAMDGCGNHYMFDMREEKRNNEYPVLFAHSGSLGYDECEQV
                     AHSFIELCTEKWALY"
     gene            complement(1398..1982)
                     /locus_tag="OF859_RS11930"
     CDS             complement(1398..1982)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821745.1"
                     /locus_tag="OF859_RS11930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_061829653.1"
                     /transl_table=11
                     /translation="MTNIQNKKQVYIIHGYTASPADHWFPWLQDKLQEDGVSVGILEMP
                     NSQSPKLNEWIEHLLQNIKVLHKDTYFIGHSLGCVSILRYLQQVSIPEPLGGLVFVSGF
                     TDPVPSLPSLDEFTNGHLDYQQIMDSLKARSVIASKDDTIVPFALSKKLAEDIQADFHE
                     VDHGGHFLQSDGFTTLPMVHQVLIEMMNANK"
     gene            2270..4015
                     /locus_tag="OF859_RS11935"
     CDS             2270..4015
                     /GO_process="GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688156.1"
                     /locus_tag="OF859_RS11935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_053325855.1"
                     /transl_table=11
                     /translation="MSNKLSDRTKKGKGFRDLKVTTTMISMIVISLVGLLIVSLVGVIG
                     MYQAKEGQGILYVDRFQHQTNILEVKSDFYNMRANYTKILDNKEYTDKQYKQVQKGKDS
                     VTTGLNEFSQRNLDAKEQKMYEELRGSIDTYYQDIEQIMAVKKNSGTYDTEERGRINKS
                     STAIVTMLTTISDYNNEQSANLYQNTQNEIKMRTIVLITVLALVLAILITISFAAIRNI
                     RFRMSTITKYCEEITQGNLTAALDPALLKGNNEIAVIARAIQQMTDSTSMVITGVIKES
                     RQINQLSDQTNHNMTDLNERIRDVSATVEQLSAAMEETSAYTENMNHSAEEMQRAAEYI
                     SVKTQERAQSAHDTSVKAETLKHAASESNKAAKEIYRKANEKMKEALERAKAVDQIRLL
                     SQSILEITAQTNLLALNASIEAARAGESGRGFAVVANEIRKLADGSKHAVDQIQSVTQE
                     VVQSVENLTTNAEELLHFLQAQVGKDYQLLEDTAGQYYNDAVEHTNTVNDLNATSKQVN
                     ATIQTMVRAIHEIATASEQSAISTQHIAENMVSSTEKSLEVAHQSDQVKGSAARLNELV
                     EGFKI"
     gene            complement(4088..4687)
                     /locus_tag="OF859_RS11940"
     CDS             complement(4088..4687)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345181.1"
                     /locus_tag="OF859_RS11940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1697 domain-containing protein"
                     /protein_id="WP_264454725.1"
                     /transl_table=11
                     /translation="MIYIALLRGINVGGNNKIEMKRLKQTFENAGMGHVTTYINSGNII
                     FSSQTQSNQELSLILEQAILEDFSLPIRVIVRNMKEIQSIMEALPNEWSNDTQMKSDVM
                     FLWDEINDISVLDKLPLKPGIGHVIYTTGAVLYSVSKEQVTKSGLTKLVGTKLYQQMTV
                     RNVNTTRQIYKLMQMAEQEELQDTSSDRNPKATLGG"
     gene            complement(4722..5372)
                     /locus_tag="OF859_RS11945"
     CDS             complement(4722..5372)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017428289.1"
                     /locus_tag="OF859_RS11945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_264454726.1"
                     /transl_table=11
                     /translation="MKQLSEALARFVQQQNLYNDAYGLFQNHDIQPRMEKISDCWDNQI
                     PVSPELEYLYSHYEMIDAKAVGTHKLKNAAVEIGDAAVLFFAAPEHLYRQQLGYRWITS
                     GELVQESSSWPPHHVVIATFNDDPVIVDTSALGSPVYAAFEGGVPQQIADSLANFFTAL
                     SILIEGACTFKGELKDEETYETKAEYIEHVKPLLHPLLSENQTTYLMEYLSLC"
     misc_feature    5460..5473
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.61"
                     /tool="antismash"
     gene            5585..6577
                     /locus_tag="OF859_RS11950"
     CDS             5585..6577
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013311297.1"
                     /locus_tag="OF859_RS11950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_023989660.1"
                     /transl_table=11
                     /translation="MSFSKIYDYKLRAYFNERISDLSHEYLFYSYPDQEQNLRILTLNI
                     NEQDYVSLVRWHDLFDRSLFTKMDDVIRSELDAERLVRLLSFIFNVFDIHKDVAYRRKN
                     LFCFYYQYQVSHLRERGNEFSLTQDRLFFLHHLLFELGLGDDIYDRLTIENNRIMYRME
                     DAQHYDLHILINILHEHINKSKMDMDTQATLEKIKFLQGQWVNFMLGSHDVYDFPFDDF
                     NKPFVEATMFMQAYKSNKNRVLEVLIDCINEHQSPTEQFISHLILMNYSYFVLKRDPSE
                     ITYLKLFCKKKPGVFMKVLTALLDIRFFVDKSSFTNVGIDYYLSRVKGD"
     gene            6580..7665
                     /locus_tag="OF859_RS11955"
     CDS             6580..7665
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372338.1"
                     /locus_tag="OF859_RS11955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_160790285.1"
                     /transl_table=11
                     /translation="MPFHHVSLPDLPPSIGRLTAIHPLKGDSQESITLLALNTQAELWR
                     LELRSGSAELCTRICIPDFNPMQPVQMVTSSDGSYVAISNRFGRHAAVYDLVHAQEKMQ
                     LSRDEYHYDKSMFPLAFVHQDGACILVHGTEWNRLDLTDIETGMLLTARPTPVYNSDSK
                     NEHYLDYFHGRLLISPGGKWIADTGWVWAPIGVVRTWSLSDWLLNPWESEKGPSVRDLW
                     QTIDWDGPVCWTGPDTLAVWGQMDADLLEEEDWGEEGVEPAVVLFDMTQPGYRRVLPAI
                     PSLNCEPVEDGTFPFPQADMAICGDQLFLWGKGVPLQVWRLSSGVREYVDTERFPLVYH
                     QEAGIFIELKADSRCKVLSYE"
     gene            7747..8700
                     /locus_tag="OF859_RS11960"
     CDS             7747..8700
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013311293.1"
                     /locus_tag="OF859_RS11960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_160790284.1"
                     /transl_table=11
                     /translation="MALIKDRFLGCLVGLAVGDALGTTVEFSSPGTFEPVTDIVGGGVF
                     GLKPGQWTDDTSMALCLAESMVRKDGFDPADQMRRYTNWYHLGYMSSTGTCFDIGGATR
                     AALHRFEATGDPYSGSVDPMTAGNGSIMRLAPVAMAYANRPEEAVMYAEMSSRTTHGAV
                     ESVESCAVLASILVAGLRGADKESMLSADVCYKWRQDEPAYSAAIEEIIRGSYRHKEPP
                     EIQGTGYVIRSLEAALWAFHHSTSFEEGALLAVNLGDDADTTGAVYGQIAGAYYGISGI
                     PSRWREKLAMKETIDELTEALWQKVEKDQTLQGEHP"
     gene            8860..9780
                     /locus_tag="OF859_RS11965"
     CDS             8860..9780
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688151.1"
                     /locus_tag="OF859_RS11965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_076295497.1"
                     /transl_table=11
                     /translation="MSHPHKQLHSFVDISNDIKGFEIVSTQFGPDGRVYILLIDKVPER
                     VRGMFTPASLKDRHTYKVLILDDHIQEVCVEGQQFNYHYVQPLKNHLLLVGARCHYYGP
                     GQYDLNGKILDYEGHTVNEMLLGDGIQSVQVTEEGTIWTSYFDEGIFGNYGWVEPVGSS
                     GLVAWNEKGDKIYENQAAAIDDCYALNVVSEQEIWFYYYSDFSLGRISGSDHTNITLMN
                     PRISGCSGVATDGYHFLFDGGYGKSGQYVLKKNVKPGSLSKGQNIRFLNDDQEFLQPHE
                     QDFRKNRLLLREGSLLYQVAIEELL"
     misc_feature    complement(9977..9991)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.4"
                     /tool="antismash"
     gene            10001..12388
                     /locus_tag="OF859_RS11970"
     CDS             10001..12388
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007431396.1"
                     /locus_tag="OF859_RS11970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_160789349.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.8e-43, bitscore:
                     144.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHYMNEKLQANTGYQLAERKAIQYFALLYDQVLDKSYVTTLTEDI
                     QKWKKNHIHHSSWLSFFSRRKRKPDTRDYNRYIQWLNYTGKLDDYLDRSVSYIYMRDLG
                     KALNSPDTHTRIQRVIADVKKHLIQSTSANGGDQPEFMNLAGVYRWAQREGIETAIIWV
                     INKLRSVSSHIPMEMDAEQAQRKLIKIIIGVILHVMEEMDDTVLPVERARRLDEAIRLG
                     YSYGLTYPFIDDLLDSQVLTVEEKEQYSRMIRTALLSGSVPELGDWTGNHMELIQYIHS
                     ELSDAFEYIKEHQRPDTQQTFFEQSYVFFHAQDIDRVKDLTRVTYTNEELYIPVILKSS
                     SSRLIVRSVISAPADEGFEQRTFFYGIYNQLADDFADMVDDMRDGAVTPYTYYLKYHHQ
                     RSDLINPFELYWAVISYLIHNVYDSDAMAREVILDRAMNGLKRYKERVGIEKYDETMEI
                     FASGNPEFNNLIQKMVQKADDVDFLDKLLRDQMITHLKNDAREKEDFFNTVKMVREQIN
                     NQLKITKPQGIPAMKEQLIEAANYSLEGDGKRIRPILTWVMGVNEYGLDASAIVPLLRS
                     LEYMHTASLIFDDLPSQDNASTRRGRQTLHQVHNSATAELTGLYLIQKAIGEQSSLDQF
                     NAETVLALIQYSAQKAEDMCMGQAMDLDSKGKALTLEQLNMVCFYKTGVAFEACLVMPA
                     MLAQIKESEIAALKKFAYHMGIAFQIKDDLLDVEGDMLLLGKPVGQDSDNNNSNFVSIL
                     GLEGASKEMWEHYCLAMEALEEIPRNIAFLKHLIHYVVNRDR"
     gene            12537..13076
                     /locus_tag="OF859_RS11975"
     CDS             12537..13076
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017428282.1"
                     /locus_tag="OF859_RS11975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CueP family metal-binding protein"
                     /protein_id="WP_160789350.1"
                     /transl_table=11
                     /translation="MKKGILVASGLVVAALGTYLIAGNIQKEGVENHETTDIKQLVHDI
                     SAGKATAQSASINSSQLIVTGDDTQTMNYDLPDNEFFVSIAPYVEQTHPCATHSLTGCQ
                     GEIKNGAFNVTVHDSEGNVIMENAAMKSQSNGFIDLWLPRDKTYRISVNHEGKTAETEF
                     STYEKNDTCITTMQLG"
     gene            13361..15424
                     /locus_tag="OF859_RS11980"
     CDS             13361..15424
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372332.1"
                     /locus_tag="OF859_RS11980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_160789351.1"
                     /transl_table=11
                     /translation="MSQNIKKRVIRSSSIANTLAMVLLVIIVVVFATLGTFMFASTQSI
                     LVKQQEAMLQTKTQAVVTQFDALFKEKGSLVKQMSTNNLFKQYLESTPSAEMVKTSPYA
                     AETVATLAAIVKAEPSFADAWIAGISGKGFFLQNDGVASKPDFDIHTRPYFKPAVEADG
                     LYYSEPYKDVNSGNVLMGIFYPFKDSSNQLIGFAAVDIAFKDIPAVMQSYSLGSTGYSI
                     LASKTGDILYHPDQNKVLKEKINESTGDLGEIGKKMIAGESGVQLINDNGERRYIGYAT
                     SKDTGWSVGLTISEDEVLSELKAFTWITIGGFAAATILLVVICYITLRYLLRSIPKLLA
                     KIKLIENGDLTVQFDTQSNNEIGQISQGIYNMVQKIQGMLQMVGGSAQVLNQSSHDLQS
                     ISSRTAITMNDTATAINEIANATNYQSIETDNILQKTGALSGQIDEIANDAKAIETMVQ
                     ISAEQSGQGLAVVDQLSRWAEENHNSTQAMSSIIQDIDLSRHEISSIVDTVNQIATQTN
                     LLALNASIEAARAGEQGKGFAVVAGEVRKLAEQTALATQEIYKKVRVIEEKTSVSVEHT
                     VHGLKIAEENARSVEDTKQVFFSINKDLEDLKLRMIQISTNTSKVHKHKDEILQALEII
                     SSTTEENSASTEEVSASTQEQLESFEQVAELSKQLNQLSNKLQDELKQFKVE"
     gene            15583..15963
                     /locus_tag="OF859_RS11985"
     CDS             15583..15963
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821733.1"
                     /locus_tag="OF859_RS11985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="immunity 22 family protein"
                     /protein_id="WP_028542320.1"
                     /transl_table=11
                     /translation="MDCFEKNVVSVWYGHFASEDELFEYVEIKYPEDENEDVFSGFLND
                     HEIDDFDEDFAEGVFQVDGTDDGIKDVSYVDSFLSPLLHDLSKIDGKYNSLFFIYDCNT
                     SGLLEKSGEKLCFLAAYPYTRD"
     misc_feature    complement(16585..16600)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.53"
                     /tool="antismash"
     gene            16596..16910
                     /locus_tag="OF859_RS11990"
     CDS             16596..16910
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OF859_RS11990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_264454727.1"
                     /transl_table=11
                     /translation="MKELDLRPRLLRWHFDDEVETDNPEEWNWIEITMHFTDGSKRWSI
                     LYTPERLLNNLSRPNIDPPGLHMQQFIVVRSYEVSDIDRVLRVFDEEDELIEASMKYPE
                     "
     gene            17089..17868
                     /locus_tag="OF859_RS11995"
     CDS             17089..17868
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OF859_RS11995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_160789353.1"
                     /transl_table=11
                     /translation="MRRKRNAVVQALSDFSTAGVTGGILNLITPLPSGLQALVTLGIPM
                     LACMYNVGDRTITNRLASKDKEKVERILYDLQIEMEKRGLEDLRRFVQFDFSTEEYAIV
                     EELVKQSINAKNEWIRKLAASILVTVGSQEVKNLKGMERCLRFMTELDDLDTQLLMLHI
                     YINHVHLVDRNKIIAEAQEIKQKIIEDDTVYAQSIKVSAEKLAFLGLVMRSTSMYPYED
                     EENSKKRIIDDFLSKNTGEITAHCISFLSFLQGTLNE"
     misc_feature    18169..18189
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 25.2"
                     /tool="antismash"
     misc_feature    18532..18541
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    complement(20974..20994)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 28.02"
                     /tool="antismash"
     misc_feature    21037..21052
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.71"
                     /tool="antismash"
     misc_feature    complement(21229..21242)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.06"
                     /tool="antismash"
     misc_feature    21936..21950
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.31"
                     /tool="antismash"
ORIGIN
        1 aggttttcaa aaatcagttc gcaggttgaa agtgaatttt ggaatacgcg ggaaggggaa
       61 tgaacatgca tactttaacg gttgaagaac tggtggataa ggataaccat gcatgggaag
      121 aggtcagaaa tattctgaaa gaaggccgga attcacatca cattgtatcg gccgaatcgg
      181 aatccgctac ggggaacacg ctgtaccgtt tgcaggtgag tacgaaatcg tatttgggaa
      241 cagttgccta tgagacagga ggaatcgtgt tcgattacgg ttggatcacc ttgctgggtg
      301 cgggtggctc tggaattttc ggtagcttga cctcatggaa cgggcttcaa gaaccggaaa
      361 gtgttcctgc gcttgagggg atgctaatgg tggcctatga tgcagcaggt ggattttttg
      421 gattggatat agggaaattc ggacgtagcg gtcatatcta ctattttgca ccagatgcat
      481 tggaatggga atccactgag ctggcctatt ccggtttctt gagctggttg gctgagggag
      541 atttgggctt gttctaccag acattccgct ggaacggttg gcagaaggat atggagcaac
      601 ttcagccggg agaggtattt gcatattatc cgccgctatg gacccaagaa ggtggagggg
      661 agaccagcag caagtcgcct atagacatta caaatgcatg gcaggtggca ttggataagg
      721 aatagctttt gtggtataaa caacaactct tagaggcatc aaggcatgga ggttggcaca
      781 tatgtggagt attcaatttg aacaaccgtt tgtaataagt caggaagcaa ctgatgaaca
      841 aatcgcgaat tttttgaaaa catggaacat aaagctatcc gagcaagaga ttcacgaaat
      901 caagcaaaga caagtgaacc cttttccaaa gtcgtctcct ttctatgatc aatataaacc
      961 tttagatcct gtgggctggc atctgcccca aggacaattt cctgacagct atatggagtt
     1021 tttgaaatat tctaatggtg gggagtttca aaatggagaa cgttattttc agtttttcaa
     1081 taccgaagat ttgagagaaa tgaacctcgc ctacgagttg ccggaatata tgccgggtgc
     1141 tgtgtcgttt gcgatggatg ggtgcggaaa ccactatatg tttgatatga gagaggaaaa
     1201 aagaaacaat gagtatcccg ttctttttgc tcattctggt agtctgggat atgacgaatg
     1261 tgaacaggtt gcccattcat ttatagagct gtgtacggaa aaatgggcat tgtattgatg
     1321 tattgaaccc gcaataatga acccttcgcc ggttccattt tgcgggttat gtaagttttc
     1381 aaactaagcc tgtcatgcta cttatttgca ttcatcattt caattaacac ttgatgtacc
     1441 atcggtaagg tggtaaaacc gtcactttgt aaaaagtgtc ctccatggtc tacttcatgg
     1501 aaatcggctt ggatgtcttc agctagtttc ttactgagtg caaagggcac aattgtgtca
     1561 tcctttgaag cgataactga acgcgctttt agcgaatcca tgatttgctg ataatccaaa
     1621 tggccatttg taaattcatc taatgacggt agactcggca ctggatcagt aaaaccggaa
     1681 acgaaaacga gaccaccaag tggttctggg atacttactt gctgtaggta tcttaatatg
     1741 gatacacatc ccaagctatg accaataaaa taggtgtctt tatgtagaac tttaatattt
     1801 tgtaatagat gctcgatcca ctcattaagt ttgggggatt gcgagttggg catctccagt
     1861 atacctaccg atactccatc ttcctgtaat ttgtcttgta accaagggaa ccaatgatcg
     1921 gctggcgaag ctgtgtatcc gtggattata tatacttgtt ttttattttg tatgtttgtc
     1981 acaatacttt ctctcccatc attcagcgtt cgttttttat atgtgcccca cttcgtgtaa
     2041 ggactcctct tctagtttag caaattcttt aagcccatga atatctaaaa ttttgagtta
     2101 catagcaaat ccaaatatga agttgcctac tataatattc ttatttttgc agtaccgtta
     2161 ttttacttat aaatttaagc gctttctacc gatatataga tatatatatc atcacgttct
     2221 gtgatctgca gcgtgaacta ttatccatag acgatctgga ggggtttgga tgagtaacaa
     2281 gttatcagac aggactaaaa aagggaaggg ttttagagat ttaaaggtta cgacaacgat
     2341 gatctccatg attgtaatca gcttagtggg tttactcatt gtatcgttgg taggggttat
     2401 cggtatgtat caagctaaag agggtcaagg tattttgtat gtggatcgct ttcaacacca
     2461 aacgaatatt cttgaagtca aaagtgattt ctataatatg cgggctaatt atacaaaaat
     2521 actcgacaat aaggagtaca cagataaaca gtataagcag gtgcagaaag gaaaagatag
     2581 cgttacaacc ggactaaatg aattctcaca aaggaatttg gatgctaagg aacagaaaat
     2641 gtacgaggaa ctacggggga gtatagacac atattatcag gatattgagc aaatcatggc
     2701 agtcaaaaaa aatagcggaa cgtatgacac ggaagagaga ggccggatta ataaatccag
     2761 tacggcaatt gttacgatgc tgactacgat ttcagattat aacaatgagc aatccgccaa
     2821 cttatatcaa aatacgcaaa atgagattaa aatgcgtaca attgttttga tcacagttct
     2881 ggccctcgtg ctggctattc ttatcaccat ctcctttgcg gccattcgaa atatccgttt
     2941 tcggatgagt actattacga aatactgtga ggagattacc caaggaaatt taacggcagc
     3001 acttgatcct gccttgctta aaggaaataa tgagatcgct gtgattgcgc gtgccattca
     3061 acaaatgaca gattcaacct caatggtcat tacgggggtt atcaaagagt cacgccaaat
     3121 taaccaactg agtgatcaga cgaatcataa tatgacagat ctcaatgagc ggattagaga
     3181 tgtatctgcc acggtcgaac agctgtcagc agctatggaa gagacttcgg catacaccga
     3241 aaatatgaac cattcggcgg aagaaatgca gcgggcagca gagtacattt cggtcaaaac
     3301 tcaagaaaga gctcagtctg cccatgatac aagtgtaaaa gccgaaacat tgaagcatgc
     3361 ggcaagtgaa tccaataaag cggccaagga aatttaccgg aaggccaatg aaaagatgaa
     3421 ggaagcgcta gaacgagcca aggccgtaga ccaaattcgt ttactttctc agtccatctt
     3481 agaaattacg gcacaaacca atttgctggc tctaaatgca tccattgaag cggctcgtgc
     3541 gggtgagtca ggtcgagggt ttgcggttgt ggctaacgag attcgcaagt tggcagacgg
     3601 ctccaaacac gcggtagacc aaattcagag tgttactcaa gaagttgtgc aatcggtaga
     3661 gaatttaact actaatgccg aggaattact gcacttcctg caagcccagg taggcaagga
     3721 ttatcagctg cttgaggata cagcaggaca atattacaat gatgccgtgg agcatacgaa
     3781 cacggtcaat gatttgaacg ccacctctaa gcaggtgaat gcaaccatcc aaacgatggt
     3841 gagagcgatt catgagattg caacagccag cgaacagtcc gctatatcca ctcagcacat
     3901 tgcagagaat atggtttcat cgacggagaa atctcttgaa gtggcacacc agtctgatca
     3961 ggtgaaggga agcgctgccc gactgaatga actggtcgaa ggctttaaaa tttaacgaga
     4021 caatatataa agacttttac atcgaagaaa aacagttggg gagccctaaa aaggctcctt
     4081 tttaagttta ccctcccaac gttgcttttg gattacggtc agaactcgta tcctgcaact
     4141 cttcctgttc agccatttgc atcagcttat aaatctgacg agttgtgttc acattccgca
     4201 ccgtcatttg ctgatacagc ttggttccga ctaatttcgt taacccgctt tttgtgactt
     4261 gttctttgct gacagagtac agaacggccc cggtcgtata tattacatgg cctattcccg
     4321 gtttcaaagg aagcttgtcc agaacggaaa tatcgttaat ttcatcccac agaaacatta
     4381 catcactttt catctgtgta tcattagacc attcattcgg cagtgcctcc ataatgctct
     4441 gaatctcttt catattacgg acgatgacgc ggatgggtaa gctaaaatcc tccagaatcg
     4501 cctgttccaa tatgagtgaa agctcctggt tagactgggt ctgactagaa aaaataatgt
     4561 ttccagaatt aatgtaagtt gtcacatgcc ccatacctgc attttcaaac gtttgcttga
     4621 gcctcttcat ctcgatcttg ttgttgccgc caacattgat gccccgcagt aatgcgatat
     4681 agatcataaa aagtcccacc tctcttcaaa aaaaaggatt tctaacaaag ggataggtat
     4741 tccattaaat acgtggtttg attttcgctc aacagcggat gcagcagcgg ttttacgtgc
     4801 tcgatatatt ctgctttggt ttcgtaggtc tcctcatctt tcaattctcc cttaaaggta
     4861 caggcacctt caatcaggat ggagagagcc gtaaagaagt tagctaaaga gtcagcaatc
     4921 tgctgcggga caccgccttc gaatgcagca tatacagggg aaccgagtgc gctagtatcg
     4981 acaatgactg gatcgtcatt aaaagtggca atcacgacat gatggggcgg ccacgaagaa
     5041 gattcttgga caagctcacc agatgtaatc cagcgatagc ccagctgttg gcgatacaga
     5101 tgttctggtg cggcaaaaaa gagaaccgcg gcatccccga tttcaactgc tgcatttttt
     5161 aatttgtgtg ttcccactgc cttagcatcg atcatttcat aatggctata cagatactca
     5221 agttcagggg atacaggaat ctggttgtcc cagcaatctg atattttctc catccggggc
     5281 tggatgtcgt ggttttggaa cagcccgtag gcatcattat ataagttttg ctgttgtaca
     5341 aaacgggcca aagcttcgct taactgtttc ataggtgttc attcctttct aattgtaggc
     5401 tatggcctcc gacaataacg tttcatttct agcctaaaga tatcataata tagatttgga
     5461 gaacatatgt ttctgtaatt gtgccgcctt gccagtctat ccagattaat tttacaatat
     5521 aggagttcga aaatgttttg tgcttagttt aatatgctca ggcttacttg taaggaggat
     5581 aagtatgtca ttttctaaaa tatacgatta caaattaaga gcttatttta atgagcgaat
     5641 ttctgattta agtcatgaat atctatttta ttcttatccc gatcaagagc aaaatttaag
     5701 aatattaacc ctgaatataa acgaacagga ttatgtttct ctagtgcgat ggcatgatct
     5761 gtttgacagg tcgctattta caaaaatgga tgatgtcatt cgaagcgaac tggatgctga
     5821 acgcctggtt cgattgcttt cgttcatttt taatgttttt gatatacata aagatgttgc
     5881 ttataggaga aaaaacttat tttgttttta ttatcaatat caagtttcac atctaagaga
     5941 gagagggaat gaattctcgc ttactcagga cagactattt ttccttcacc atctcttatt
     6001 tgaactgggt ttaggtgacg acatttatga tcgcctgacg attgaaaata ataggatcat
     6061 gtacagaatg gaagacgcac aacattatga tctgcacatt cttattaaca ttttgcatga
     6121 gcatattaac aaaagtaaga tggatatgga tacacaagca acgctggaaa aaataaaatt
     6181 tttacaaggc caatgggtca actttatgct gggtagtcat gatgtatatg attttccatt
     6241 cgatgatttc aacaaaccat ttgtagaagc aacgatgttt atgcaagcct acaaatctaa
     6301 taaaaatagg gtattagagg tgctgataga ctgtatcaat gagcatcaat ctccaacaga
     6361 gcagttcatc tcccatttga tcttgatgaa ttactcctat tttgttctca aaagagatcc
     6421 tagtgaaatt acatatctta agttgttttg caagaaaaaa ccgggagttt ttatgaaagt
     6481 attgactgca ttgcttgata tcagattttt tgttgataaa tccagcttca caaatgtggg
     6541 tatagattat tatttatcta gagtaaaagg ggattaatca tgccattcca tcacgtttct
     6601 ttacctgatt taccaccgtc tatcggacgc cttacagcca ttcatccact aaagggtgac
     6661 tctcaggaaa gcataaccct gctggcacta aacacacaag cagaactgtg gagactagaa
     6721 cttcgctctg gcagcgcaga attgtgcaca cgtatttgta ttcctgattt taatcccatg
     6781 caacctgtcc aaatggttac cagttccgac ggcagctacg tagctatctc caatcgtttt
     6841 ggacggcatg cggcagtgta tgatttagtc catgctcaag aaaaaatgca attatcacgg
     6901 gacgaatatc actacgataa aagtatgttt cccctggcat ttgtacacca agatggtgca
     6961 tgcattcttg ttcatgggac ggaatggaac cggcttgacc tgacggatat agaaacaggc
     7021 atgcttttga cagcaaggcc tacccctgtt tataacagcg acagcaaaaa tgaacattat
     7081 ctagattatt ttcatgggag gctgctgatt tcaccagggg gaaagtggat tgcggatacg
     7141 ggatgggtgt gggctccgat tggagtggtc cgaacttggt cgttatcgga ttggttgctg
     7201 aatccatggg aatcggagaa ggggccgtcg gttcgcgatc tttggcaaac catagattgg
     7261 gatgggccag tgtgctggac aggacccgat acattggcgg tttggggaca gatggatgct
     7321 gatttactgg aggaggaaga ttggggagag gaaggagttg aaccggctgt tgtcctattc
     7381 gatatgaccc agccagggta ccgacgtgtg cttccagcga ttccatctct aaattgtgag
     7441 cctgttgaag acgggacttt tccttttccc caagcggata tggccatttg cggtgaccaa
     7501 ttattcttat ggggaaaagg agtcccgctt caggtatggc ggctttcaag cggtgtgcgg
     7561 gaatatgtag atacggagcg gtttccactc gtttaccatc aagaggcagg aattttcatt
     7621 gaattgaaag cggatagccg ttgtaaagtc ttaagctacg aataaatggc agtgtcgggc
     7681 ttccttcctg gcgagatggg aaaatatgcg ttagttatta catttgaaaa ggggcgtaaa
     7741 accaaaatgg cacttatcaa ggatcgtttt ttgggatgcc tggttgggct ggccgtgggc
     7801 gatgctttgg gaaccactgt ggaattcagc agtccaggta catttgaacc tgtaacggat
     7861 atcgtgggcg gcggtgtctt tgggttaaag ccgggccagt ggacggacga tacgtcgatg
     7921 gcgctctgct tggccgagag tatggtgcga aaagatggct ttgatccggc agatcaaatg
     7981 cgccgataca ccaattggta ccacttggga tatatgagca gcacgggaac gtgctttgat
     8041 atcggtggtg caacgagagc agcactgcat cgcttcgaag ctaccggaga tccgtacagt
     8101 gggtccgttg accccatgac tgccggcaat ggctctatta tgaggcttgc acctgtagct
     8161 atggcctatg cgaaccgtcc ggaagaggcg gtgatgtacg ctgagatgag ctcacgaacc
     8221 acccatggag cagtcgaaag tgtggagtcc tgtgctgtgc ttgcttcaat ccttgtggca
     8281 ggtctgcgag gagcggacaa agaatccatg ttatcggcgg acgtctgtta taagtggcgg
     8341 caggacgagc ccgcttattc ggcagccatt gaagaaataa ttcggggatc ttaccggcat
     8401 aaagagccgc ctgaaataca aggaaccggg tatgtcattc gttcccttga ggctgcgttg
     8461 tgggcattcc accattcgac ttcatttgaa gagggagcac tgttggcagt gaatctgggg
     8521 gatgatgctg atacgactgg ggcggtgtac gggcaaattg caggagctta ttacggaata
     8581 agcggtattc cgagtcgttg gcgcgagaag ctggcgatga aggagacgat agatgaactg
     8641 actgaggctt tatggcagaa ggttgagaag gaccaaacgc tccaagggga acatccataa
     8701 agatcaagct gggctgcttt tcttataaag cagagcccag cttgtttttt tttgctatat
     8761 cgccatactt ccgccctact cagcaacatg ccgttatgac aaaatgagtt caatacaaat
     8821 aacacttcac tttattgacc tttcagagga ggaactacct tgtcacatcc acataaacag
     8881 cttcattcat ttgttgatat ttccaacgat ataaaaggat ttgagatcgt ttcgacccaa
     8941 tttggccctg atgggcgcgt gtatattttg ctgattgata aagtcccaga acgagtgcgg
     9001 gggatgttca cgcctgcctc attgaaagac agacatactt acaaggtact catcctagac
     9061 gatcacattc aagaagtgtg tgtggagggg cagcagttca actatcatta tgtacagcct
     9121 ctaaaaaatc atttgttact cgtcggagca cggtgccatt attacggacc tggtcaatac
     9181 gatctaaatg gtaaaatcct tgattatgaa ggtcataccg tcaatgagat gttgcttgga
     9241 gacggcatcc agagtgttca ggtaacagaa gaaggtacga tctggaccag ttattttgac
     9301 gaaggtatat ttggcaatta tggttgggtt gagcctgttg ggtcctccgg tcttgtcgcc
     9361 tggaatgaaa agggagataa aatatatgag aaccaagcag cagccattga tgattgctat
     9421 gcattaaacg tagtcagcga acaggaaatc tggttttatt actattcaga cttttcatta
     9481 ggacgtattt ccggtagtga ccacacgaat attacgttaa tgaatccgag gatttctggc
     9541 tgctctgggg tggctacaga tggatatcac tttttattcg atggcgggta tggaaagagt
     9601 ggacaatatg tcctgaaaaa gaatgtgaag ccaggtagtt tgagcaaagg gcaaaacatc
     9661 cgttttttaa atgacgatca agagtttctt cagccgcacg aacaggattt cagaaaaaac
     9721 cgcctgctgc tccgtgaagg ttctctgttg taccaggtgg cgatagaaga attattataa
     9781 aaacccacgt cagacgtggg tttttttgtt gattggaagt aatttgagcc tatattcttg
     9841 ttttaaattc atggatattg ccaaagaggg ggtatcgata agcagcatga taatttcgta
     9901 accttacagt tttttttccg tataaagata aaaacatgat ccaagttcgt tccctcaggg
     9961 agaaatgcaa ccatgtttaa caaaatgaga agttgaggta atgcattata tgaatgaaaa
    10021 attacaagcc aatacaggat atcagctggc tgagcggaag gcgattcagt attttgcatt
    10081 actgtatgat caggtcttag acaaatctta tgtgaccacc ctgacagaag acattcaaaa
    10141 gtggaaaaaa aatcatattc atcattcctc atggttatcc tttttttcac ggagaaagag
    10201 aaaacctgat actcgggact ataatagata cattcaatgg ctgaattata caggcaaatt
    10261 ggatgattat ctggaccgaa gtgtctccta tatttatatg agggacctag gcaaagctct
    10321 gaattctcct gacacacata cccggattca gcgtgtcatt gcagacgtaa aaaaacactt
    10381 gatccaatcc accagtgcaa acgggggaga ccaaccggaa tttatgaatt tggccggggt
    10441 gtatcggtgg gcccagaggg aaggtataga aaccgcgata atttgggtga tcaacaaact
    10501 taggtctgta tcctcccata ttcccatgga gatggatgcc gagcaagccc agcgtaaact
    10561 gattaagatc attatcgggg ttattctgca tgtgatggaa gaaatggacg atacagtgtt
    10621 gcctgtggaa cgtgctcgca gacttgatga agccatcagg cttgggtact cctatggtct
    10681 aacctatcct ttcattgatg atcttctcga ttcccaggtt ttgacggttg aagaaaaaga
    10741 acaatattcc cgtatgatac gtaccgcgct tcttagtgga tctgtgcctg agttgggcga
    10801 ttggaccgga aatcatatgg agttgattca atacatacat tcggagctct cggatgcatt
    10861 tgagtatatt aaggaacatc agcggccaga cacacagcaa acatttttcg agcagtccta
    10921 tgtttttttt catgctcaag atattgaccg tgttaaggac ctaacgcgag ttacttatac
    10981 caatgaagag ctttatatac ccgttatttt gaagtcttcc tcatcccgat tgattgtccg
    11041 ttccgtgatt agtgctcctg cggatgaggg gtttgagcaa cgaacattct tttatggtat
    11101 ctataaccag cttgctgatg attttgcgga tatggttgac gatatgagag acggtgcggt
    11161 aacaccctat acctactatt taaaatatca tcatcagaga tcggatctta tcaatccctt
    11221 tgaattatac tgggcggtta tttcctattt gatccataac gtatatgact ccgatgccat
    11281 ggctcgtgag gtgatactgg atcgtgcaat gaatggactc aaacgttata aagaacgtgt
    11341 aggtattgaa aagtatgacg aaacgatgga gatctttgca tccggaaatc cggaatttaa
    11401 taatcttatt cagaagatgg tacaaaaagc ggatgatgta gatttcttag ataagctgct
    11461 tcgggaccag atgattaccc atctgaaaaa cgatgcgagg gaaaaagaag actttttcaa
    11521 tacggtcaaa atggtccgtg agcagattaa caaccaattg aaaattacca agcctcaagg
    11581 gattccggcc atgaaagaac agcttattga ggctgcaaat tacagtctcg aaggggacgg
    11641 gaagcggata cggcctatat tgacttgggt catgggcgtg aacgaatatg gattagatgc
    11701 atcggcaatc gtgcctcttc tgaggtcact ggaatatatg cataccgcat ccctgatctt
    11761 tgatgatctt ccttcccagg ataatgcgtc tacccgtaga gggcgtcaaa ccttgcatca
    11821 ggtgcacaat agcgccactg cggaactaac cggtctgtat ctgatccaga aggcgattgg
    11881 ggaacaatcg tcacttgacc agttcaatgc tgaaacggtg cttgccttga tacaatactc
    11941 ggcccagaaa gcagaagata tgtgtatggg gcaggcgatg gatctggatt ccaaaggaaa
    12001 ggcactgacc ttggagcagc tgaatatggt gtgcttttac aaaacaggag tggcgtttga
    12061 ggcttgtctg gttatgccag ccatgcttgc acagatcaag gagtcggaaa ttgctgcttt
    12121 gaagaaattt gcctatcata tggggattgc ttttcagatt aaagatgatt tgctggatgt
    12181 ggaaggagat atgctcttac tcggaaaacc tgttggccaa gattctgata ataacaattc
    12241 gaatttcgtg tccattcttg gtcttgaagg tgccagtaaa gagatgtggg aacactattg
    12301 cctcgcgatg gaagcattgg aagaaatccc acgtaatatt gcttttctga agcacttaat
    12361 acattatgtc gtgaacaggg accgttaaaa aaacgagtgt accccattgc tccacaagag
    12421 taatggggta tttttacgtt gaatgtgaat atctggtgac ttcagcaccc catttttccc
    12481 attatggtgc attctccctt ataataatac aaaacagacg aggagatgaa ctctaaatga
    12541 aaaaaggaat cttggtcgct tcagggttgg ttgttgccgc attggggaca tacctaattg
    12601 caggaaatat tcagaaagaa ggggtggaaa accacgagac gacagacatc aagcaattgg
    12661 tgcatgatat cagtgcaggc aaggcaacag cccagtccgc ttccattaat tccagtcagt
    12721 tgattgtcac aggggacgat actcagacca tgaattatga tttgcctgac aacgagtttt
    12781 ttgtttcgat tgcgccatat gtggaacaga cccacccttg tgcaactcat agtctaacgg
    12841 gctgccaagg cgaaataaaa aacggagcgt tcaatgtgac cgttcacgac tccgaaggga
    12901 atgtcatcat ggagaatgcc gctatgaaat cacaatccaa tggttttatt gatctatggc
    12961 taccgaggga taaaacatac cgcattagcg tgaatcatga aggtaaaacg gctgaaactg
    13021 aattctctac atatgaaaaa aacgatacgt gtatcacaac gatgcagttg ggttaacgac
    13081 ggaggatgag gggtgagctt gcggatcgct gaaacgctct aaatccgcaa aactctgcgt
    13141 tctcatatat agcttttagt aaagagccta cgtctgacgg aggctctttg tgctgcccta
    13201 atcttttgct ggagttaccg aacaggttgg aaaggaatct atgaggaatc aggtagcaaa
    13261 actttaaatt gtgtatacta aaaacctatt aaaatagctg caaacttccg acatattatc
    13321 taagagcttt tcgctcaata ttcctcgggg agatggcagc atgtcacaaa atattaagaa
    13381 gcgcgtaatc agatcatcca gcatcgccaa cacattggcc atggtcttgt tagtcattat
    13441 cgttgtcgtc tttgcaacct tggggacgtt catgtttgca agcacgcaaa gcatacttgt
    13501 caagcagcaa gaggccatgc tccagaccaa gacgcaggcc gttgtcactc aattcgatgc
    13561 gttgtttaag gaaaagggat cacttgtcaa acaaatgtca acgaacaatc tttttaagca
    13621 atatttagaa agcaccccat cggcagaaat ggtgaaaact tctccttatg ctgcggaaac
    13681 agtagcgact ctggcagcca ttgtaaaggc agagccatct tttgccgacg cctggattgc
    13741 aggaatatct ggtaaaggct tctttcttca gaatgatggt gttgcttcta aaccggattt
    13801 tgatattcat acacgcccat acttcaaacc agctgttgaa gcagacggtt tatactactc
    13861 agaaccctat aaggacgtca attcgggtaa tgtgctcatg ggcattttct atccgttcaa
    13921 agatagcagt aatcaattaa tcggatttgc tgcagttgat attgctttca aagacatccc
    13981 tgccgttatg caaagctatt cgcttggaag cacaggttat tcgattcttg catccaaaac
    14041 aggtgatatt ttgtatcacc ccgatcaaaa taaagtgctg aaagaaaaga ttaacgaaag
    14101 cacaggtgat cttggggaga ttggaaagaa aatgattgcc ggcgagtccg gagtgcagct
    14161 aattaatgat aatggcgaac gtcgttacat tgggtatgca accagtaaag atacggggtg
    14221 gtctgtaggc ttaaccattt ctgaagatga ggtgctctca gaattaaaag cgtttacctg
    14281 gattaccatt ggcggttttg cggcagccac catcctgctc gttgtgattt gttatataac
    14341 gctccgttat ctgttgagat caatcccgaa attgcttgca aaaatcaagc tgattgaaaa
    14401 tggagatttg accgttcagt ttgatacgca atccaacaat gaaatcgggc aaatttctca
    14461 aggaatttac aatatggttc aaaaaattca aggcatgctc caaatggtgg gtggctcagc
    14521 tcaagtgttg aatcagtctt ctcatgattt gcaatccatt tcttccagaa ccgcaatcac
    14581 gatgaacgat actgcgacag caattaatga gattgccaat gcaacgaact accaatccat
    14641 cgaaacggat aacattttac aaaaaaccgg agcattatcc ggccaaattg acgaaattgc
    14701 caatgatgcc aaagccatcg aaacaatggt gcaaatctct gctgaacaaa gcggacaggg
    14761 gcttgctgta gtagatcagt tatccagatg ggcggaagaa aatcacaatt ccacacaagc
    14821 gatgtcgtct attattcagg atattgatct gagccgtcat gagatttcca gcatcgtcga
    14881 tacggtcaac caaattgcaa cgcagaccaa cctgctggcg ctcaatgctt ccattgaagc
    14941 tgcacgtgca ggagaacagg gcaaagggtt tgctgtggtt gccggagagg ttcgcaagct
    15001 ggctgagcag acggcgctgg cgacacagga aatctacaag aaggtacgtg tgattgaaga
    15061 aaaaaccagc gtatcagttg agcatacggt tcacggtctg aaaattgcag aagaaaatgc
    15121 cagatcggtg gaggacacga agcaagtatt ctttagcatt aacaaggatt tggaagattt
    15181 gaaattgcga atgattcaga tcagcacgaa cacctccaaa gtccacaagc acaaagatga
    15241 gattttgcag gcgttggaga ttatctcttc taccacagaa gagaattccg cttcaaccga
    15301 agaggtcagc gccagcacgc aggaacaatt ggagagcttt gaacaggttg ctgaactatc
    15361 caaacaatta aaccaattgt ccaataagct tcaagacgaa ttaaaacagt tcaaggtcga
    15421 gtagcaagtc tactaggcat gattttgact tatatacagc aaagcccgcg atcagcgcgg
    15481 gctttttagc tttaacagct gttgtgggat agagagcatg gtagctggtg cgggatacag
    15541 atagactata cgtataaact gaaatattag cggggtgaag atatggattg ctttgaaaaa
    15601 aatgttgtgt ccgtctggta cggtcacttt gcctctgaag atgagttgtt tgaatatgtt
    15661 gagatcaaat acccggaaga tgagaatgag gatgttttta gcggtttttt aaatgatcat
    15721 gaaatagatg attttgacga agattttgct gaaggagtct ttcaggttga cgggaccgat
    15781 gatggtataa aagatgtttc ctatgttgat tcttttttat ctccactatt acatgatttg
    15841 agtaaaatag atggtaaata taattcgttg ttctttatat atgattgtaa tacaagcggt
    15901 ttgcttgaaa aaagcggcga gaaactatgc tttttagccg cgtatcctta tacaagagat
    15961 taacgttaca ttattccact gttttcggag tcttatttca agtaattata taatgaaaat
    16021 tgaacttaaa ggatcaataa tttgatccga aagaatcagg gacttaaggt aaatttccat
    16081 cttaaggccc tttttttgtg caaaattaga tttccaaatt tttgaacggc tgatatacta
    16141 aggagacaag tgagatgaag ataaacctac tctatcggga tgaagcagga aggttcggca
    16201 agcgctgctc tcagaagcgg cttttgtgat ggtcgagcag tacaaagagg tggagcagcc
    16261 ggaagactgg ctatttccag agcagagaaa aggccgccac ctgacggaac gttaagctta
    16321 gattgatctt cgctattttc aggaactgct ggggcatcag agtgtgcgaa cgacggagcg
    16381 gtatacacat gtgagcaggc gggacattgg gcggattcaa agtccgttgg atcggatgag
    16441 cgggcaggag gattgaaacg cagaaagtgc gggaatcagg aacaaagtgc aggattcacg
    16501 aagttcgtga ataggacgaa gagagcattt tttcggaagt tcgcaaataa gacgttagct
    16561 gaaattgata ggttgcaaag agaggtgaaa acattgtgaa agaactggat ttaagaccaa
    16621 ggctattaag atggcatttc gatgatgagg ttgaaactga taatccagaa gaatggaatt
    16681 ggatagagat cacgatgcat ttcacggatg gttccaaaag atggagcatt ttatatacac
    16741 cagaacgatt gctaaataac ttgtctaggc caaacataga tccaccaggt cttcatatgc
    16801 aacagtttat tgtagttaga agctacgaag ttagtgatat tgacagagtg ttaagagttt
    16861 tcgatgagga agatgaattg atagaagcct caatgaaata tccagagtga ttcgaagaag
    16921 tcagcaacat catctaacat tatatccacg catcaggcat acgccctcgg tccggcagaa
    16981 ggatttcggg gaggcaggag cagccggaca cacccaacat tcgctgggcg tcatgaatac
    17041 ggggacgtta tacataattc aaaatacatt ttaaataagg agtattacat gagaagaaaa
    17101 aggaacgcag ttgttcaagc actatcggat tttagtactg ctggtgtcac gggaggaata
    17161 ctaaatctta ttactccttt accttcaggc ctccaagcct tggttacttt aggtatacct
    17221 atgcttgcat gtatgtacaa tgttggagat cgcacaatca ctaatagact tgcaagtaaa
    17281 gataaagaaa aggtagaaag aattttatat gatcttcaaa tagaaatgga aaaaagagga
    17341 ctagaagatt tgaggagatt cgttcaattt gatttttcta cagaagaata tgcaattgta
    17401 gaggagttag ttaaacaatc aattaatgct aaaaacgaat ggataagaaa attagctgct
    17461 tctatattag taactgttgg ctctcaggaa gtaaagaact taaaaggaat ggaaagatgt
    17521 cttagattta tgactgaatt agacgacctt gatactcaat tgctaatgtt gcacatatat
    17581 ataaatcatg ttcacttggt agatagaaat aaaattattg cagaagctca agagattaaa
    17641 caaaaaataa ttgaagatga tacagtatat gctcaatcta taaaagttag tgcagaaaag
    17701 ttagcatttt taggactagt aatgcgttcc acttctatgt atccatatga agatgaagaa
    17761 aactctaaaa aaagaataat tgatgatttt ttaagtaaaa atactgggga aattactgct
    17821 cactgtattt cctttctaag ttttcttcaa ggaaccttaa atgaatgaat taacaatata
    17881 attcataatc aatgaacagc gtataacata atactcacgc tgcggacatt cgtccttggc
    17941 ccggcatacg ccggacaccc agcatacgct gggtcgtgaa tacaggaacg ttagatgaaa
    18001 ctggcgaaaa gataccacaa ttcgcaattc aacaaatcaa taatttcgtt taaattaatg
    18061 attgaaagga gcatagaatt tgacaaacga tatacctttc tataaatata atgggcttta
    18121 tgaagttgcg atgctcaaac atattattac aacaagtcgt gatatcttat ttggtcaaat
    18181 cgaccattac aaaattgaaa taaataatga agcggatctt cagctccact tttcgtatat
    18241 attaaaaagc gtaggagaac tattcaaatt tggtataaat cacaatctga aaataatctc
    18301 gaaaccccat tcagatctgc aaatactcta tcaaaaagtg gttctaatag atcaaaaatt
    18361 gatataacat tggaatggta tggaagcact acccaagtta caacgtgcgc aattgaattg
    18421 aagtttttcc ttagggataa acttcgtgag ccccataacc gttttgatgt cttttgcgat
    18481 ctgaagaatt taaaagagta tgctcagttg tccagagatt ttaaaatcgg atattttttg
    18541 ataggtacag acaatactca ttatgttaat caaaaatcat attcaaatgg tactaaggat
    18601 tttgattttc gacataatac aaagtatgaa gctaatactg tcttaactta cagcgctaga
    18661 aatggtcata ataagacgat atatctaaac aatgattatt atttttcatg gcaaagagta
    18721 agtcgctttt atttcttaga tcattttatt tataggaaat agagtttatg taaacaagaa
    18781 tttagcaggt atttcaagat gtcgccagca tcatctaaca gtttatttac gcggtgatcc
    18841 ttgcggatct tggtctgcca gaagtaattt cagagtagca aagtcaggca gacaacccta
    18901 cgaggcgaag tggcatagcc acccgatagc tggcgctgcc actttgcctc atagggttcg
    18961 taaataaggg aacgttaggc gaaattacta tttgaaaatg gtttaatatg aaattaatca
    19021 ttcaagaatt acaagcagaa tcgtataatc aaaaaaatca acatctaagt tacttagaaa
    19081 aatatattta gtggacaaaa agcttaatat aatcgaattt cgaaagaggc cttatgaaga
    19141 actgaataga tttgaaacta taacaatatc tcaatacata gagatatatt attaataaat
    19201 atgggagtaa acaacatgga tgaaaaaaag tttatagaag atctatacat tgaaaagacg
    19261 aaaaatgata ctaattctaa aacgttagcc aatgcattgg atatgattac taagactgta
    19321 tttgaagact cgaatagatt tatttttgaa ctaattcaaa atgcagatga tgctcctgta
    19381 caatcaggag tagccaatat taaggtcgaa ataagattgc tagaaaaata cttaattttc
    19441 agtcatacag gtaagcattt tacaaaggaa gacgttaaag gaatatctga cttaggtagt
    19501 ggagatagtg gaaaaacgaa agatattgaa aaaacaggat ataaaggaat aggttttaaa
    19561 tctattttca atacttgcga tttagtatat attctttcga aaaatttcac cttcaaattt
    19621 gataaaaatc atgagaagtg gagaaatgcc caaaattatc cctggcagat aattcctatt
    19681 tggtttgaag aaattgattt agataaagaa gttcgaaacg agattaacag attgaatgtg
    19741 atcacaatag ttcctatcaa caaccgggaa caaatcaaaa gagaaataat agaggttttt
    19801 agtgactcta ggattatgtt atttttgcgg catatttctg tattgacatt tattgatggt
    19861 agtgcacagg aattgcgatt aacacgtgaa caaggcgatg atggccttaa atctatatct
    19921 gtcaatggat tgagaaaaag tcgctggtta tacaaagaat ttattgttcc agtggatata
    19981 gatttaaaag agaaaataaa aaacctcgat aaagcaacct atccagataa attaaaagaa
    20041 gcaacaaata ttaagatttc atttgctgct tccgttgctg agaatggtga tatagaggaa
    20101 atatctgaag ctcaacttta ttgttactta ccgacaaagg tccagcataa ctttaacttt
    20161 ttaataaatg gagacttcat aacaaatgca gaaagaacga gaattcttga aaatgactgg
    20221 aatggattta tatttaagca gatagctatt tgcaaaatca agtggttagc tgaattagtt
    20281 cgagatttta agtataaata tcaatttacg agactaataa gaggtaagtt ttcttcattc
    20341 ggttctttaa caagtaaaag ttataatgaa ggtctcgata gtgcaattgc tgaaatacct
    20401 tttattccgg ttcaggatta tgagaatgtt tactcaaaaa taagcggttg tattatagac
    20461 aatactggat ttagtgagga gtttggaact ggattaattt taagtcaata tagtgaaaaa
    20521 tttaatgtag ctaattgtaa aattaagaat cagaggatat tagcagactt aggtgctgaa
    20581 ataattgaca agaaagagct gtgtggatta tttgcaacag aaacatttaa aaaaatgctt
    20641 aactcagatg tacaatataa tataagattg attaaatttt tgcatcaaaa agatagcaag
    20701 tctggatggt caacatattt gaaaacagtt ccatttttgc tagatgaggt ccaacaattg
    20761 agtccgccag aaaatttata ttacccatta cctgaagggg aaatgggaat ctctgatgtt
    20821 gtctctatga gatgtctgaa tgttcaggtt ttcgaaaata taaaaaaaga tgataagctt
    20881 gttatgtggc ttacattatt agggatcagt gaaccctctg agatagatat tttaagaaaa
    20941 tcgatctttc aaatgattga ctctgattta attaatatat caaatgcttt gtttatagga
    21001 agatttgttg ttaaagtctt tgataaagga attcttaatg acaatgatta taaaaagttg
    21061 tccaatctga agttactaac aactaaggta agtttacaac ttcccaataa atgctacttt
    21121 tctgattatt ataaaccaga gttgagcctt gagaatttct ttactgaggg ggattatgta
    21181 tctcctcagt atatccaaga ggaatcagag ctgtatagtt ttaagaaatt gtttttaaaa
    21241 ataggtgtgc aacagaagat aaaaatctct attgaagaaa gcatcgaaag gcaaaatctg
    21301 gtgaggaagt atccctcagt tcaatcatat ctcaacttta tagataatgg agacttttat
    21361 ccgcagcaga caaaaactta tatttacaga ggacaacatg gattgaaaaa tttcgtgtat
    21421 gtccagtata tggagtacac aaataatcta aggttttcta ttaagttatg gaaaataatt
    21481 tttggcaacc actggaatga gctttattcc aaatccttga gttcaaaata ttacacatat
    21541 ttcggagatg ccagcttaga taaaagttca tatattcagt attacgtaaa aaacaatccc
    21601 tctataccga gtgatgatgg acaatgttat aaatcaatag acttatattc cagaagttta
    21661 ataaaaatcg tcggtgactt ttatcccgtt gtgcatagag atatctcttt aaataaagaa
    21721 caagaggaat ttctcgcgat taaaactagg gttaccaccc aggattgttt atgtctgctt
    21781 gagaagttag aaggtaaccc agtaagcagt cttacactaa agaaagtcga ttcgatatat
    21841 caacaaataa ttaataataa accggtaaac gagaataatc ttaagattaa atatttaaag
    21901 ttgttggcaa cagatgattc atttcaattt gcttctgaac ttcatttttt tgatgttaag
    21961 gggataatgc ctcccagtaa ttctaagttc tttataaaaa tatcgggaac aaaaaaagat
    22021 aaccaaatat tatttgatta tttcgatata cctgtaataa aaaacgagga ccttcaactt
    22081 gataccacgg gtgaagaaag tgatgaaaaa cttaagaaaa aactacttca aaagtcaaag
    22141 tacttagcta tgcttattgc taatattaac gcagaagatc ctttagaaat tttatataac
    22201 ctaacaagga caatcaaaga tgcaaatttt aaaagggctg aatcgttatc tttactactg
    22261 atcaatagag cagggacaga aatatacaat caaactattg attcctggta tcatgctgaa
    22321 tcaaattcgg tttattatgc aggttcttta actaatcctt tgacacttta taatctaagt
    22381 aactctct
//
