LOCUS       NZ_CP107567            10402 bp    DNA     linear   CON 18-NOV-2023
DEFINITION  Streptomyces peucetius strain NA0869 chromosome, complete genome.
ACCESSION   NZ_CP107567
VERSION     NZ_CP107567.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces peucetius
  ORGANISM  Streptomyces peucetius
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8050611)
  AUTHORS   Zhao,E. and Ge,H.
  TITLE     Cytochrome P450 Catalyzes Benzene Ring Formation in the Biosynthesis
            of Trialkyl-Substituted Aromatic Polyketides
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8050611)
  AUTHORS   Zhao,E. and Ge,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2022) School of Life Sciences, Nanjing University,
            No. 163 of Xianlin Avenue, Qixia District, Nanjing, Jiangsu 210033,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: unicycler(0.4.8) v. v. 3
            Assembly Name                     :: NJU_NA0869
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/18/2023 06:49:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,216
            CDSs (total)                      :: 7,126
            Genes (coding)                    :: 6,825
            CDSs (with protein)               :: 6,825
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 303
            CDSs (without protein)            :: 301
            Pseudo Genes (ambiguous residues) :: 0 of 303
            Pseudo Genes (frameshifted)       :: 144 of 303
            Pseudo Genes (incomplete)         :: 227 of 303
            Pseudo Genes (internal stop)      :: 22 of 303
            Pseudo Genes (multiple problems)  :: 85 of 303
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:23:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7481268
            Orig. end                         :: 7491670
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP107567.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from IFB-NA0869, Nanjing
            University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10402
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="melanin"
                     /region_number="27"
                     /rules="melC"
                     /tool="antismash"
     cand_cluster    1..10402
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10402
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5402](+)"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5402
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="1"
     misc_feature    561..574
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.03"
                     /tool="antismash"
     gene            863..1609
                     /locus_tag="OGH68_RS33755"
                     /old_locus_tag="OGH68_33755"
     CDS             863..1609
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513070.1"
                     /locus_tag="OGH68_RS33755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_33755"
                     /product="succinate dehydrogenase/fumarate reductase
                     iron-sulfur subunit"
                     /protein_id="WP_264249286.1"
                     /transl_table=11
                     /translation="MKLNLRVWRQQNPDAEGAMATYEVDGISPDMSFLEMLDTLNEDLI
                     LRGEEPVAFDHDCREGICGACSLVINGDAHGPERTTTCQLHMRSFRDGDTIDVEPWRAS
                     AFPVVKDLVVDRSSFDRIIQAGGWISAPTGSAPEAHATPVPKPDADFAFEHAECIGCGA
                     CVAACPNGSAMLFTSAKVNHLGVLPQGAPERETRVLDMVAAMDDEGFGGCTLTGECASA
                     CPKGIPLPSIAAMNREWLRATRKVRR"
     gene            complement(1599..2660)
                     /locus_tag="OGH68_RS33760"
                     /old_locus_tag="OGH68_33760"
     CDS             complement(1599..2660)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951399.1"
                     /locus_tag="OGH68_RS33760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_33760"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_264249288.1"
                     /transl_table=11
                     /translation="MSEHTNMRHDDGRRTFVRRTLLRGAAVGAAAPLLPAAAGAAQAAP
                     DAAPVGADAAPVGSAGSASGAVRPDAATLRWLGTSGWRIGVGVGGRTVLFDPYITRFPT
                     GLFGPKGFDPDTRLRSDEELVARHAGRPELVLVSHTHWDHVGDVPCIATSTGARVIGTE
                     TTYHVLRALGVDAGQISVVKGGEVLDFDGFTVEVVASRHSRNAKWSYFAPGTLHAPPRP
                     APRTVSDLPEGDTLAFQVTVADGPSFFLMGASDFDERSAAGLRPDVLMAATPSSRSTHR
                     YLPRLLSTLGNPGTVVPVHWDNFEEPLSAPPRRDPAMDLDAFTAEVRRLSPASRIVVPD
                     YATVYGADLRPTA"
     gene            complement(2745..3644)
                     /locus_tag="OGH68_RS33765"
                     /old_locus_tag="OGH68_33765"
     CDS             complement(2745..3644)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825398.1"
                     /locus_tag="OGH68_RS33765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_33765"
                     /product="serine hydrolase"
                     /protein_id="WP_264250417.1"
                     /transl_table=11
                     /translation="MRVEERLGAVFAAAGAAGALHAVDIDGPGEVGCRPDEPVVVASVF
                     KVLLVLEFARQAAAGQLDPRERVRVSADRRLGGWGTGGCLDDVELSLRDLAHFAMAVSD
                     NTAADLLMERVGADTVALLAAELGLVGTRIVGGPRQLLESMLAEVGAQDEREFAAVFPT
                     LSPEQVRALGVHDPARTNASTPREMTRLLRMVWRDEAGPPQACAQVRDLMARQVFRHRL
                     AAGFGDGVRVAAKTGTLPGLHNEVGVVEFPDGGRYAVAVFARTPDLVANHTQTDVAIGT
                     AARTAVDLLRGTGTGQPL"
     gene            3693..4634
                     /locus_tag="OGH68_RS33770"
                     /old_locus_tag="OGH68_33770"
     CDS             3693..4634
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825397.1"
                     /locus_tag="OGH68_RS33770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_33770"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_264250419.1"
                     /transl_table=11
                     /translation="MRHLRIFVAVADELNFGRAAERLGMAQPPLSRAVRRLEDDLGAEL
                     FDRSRRQVRLTPAGSVLLDEARELLAREERTRALVRRARDGDLGTLRAGVPPDTSAAVL
                     SALLVRCDERGLRVDLQEVTTDEQLRLLASGGLDTGLVHQPVDATELELGPEVRIELGV
                     VLPRTSPLARLPEVAVGDLAGHDLVLFPRTSAPGWYDTTLDVCRREGFVPGRIRHARNP
                     EFLIGLVTAGHGVAFDQGTVARKEPRAAWRPLVGRPLAQRICAAWPRRSPHGAAAREFA
                     AVAAEVLGRDRTAVPYGGGGEAGPRPWSVVYG"
     misc_feature    complement(4721..4735)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.13"
                     /tool="antismash"
     gene            5001..5402
                     /locus_tag="OGH68_RS33775"
                     /old_locus_tag="OGH68_33775"
     CDS             5001..5402
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240684.1"
                     /locus_tag="OGH68_RS33775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_33775"
                     /product="tyrosinase cofactor"
                     /protein_id="WP_264249289.1"
                     /sec_met_domain="melC (E-value: 7.7e-44, bitscore: 148.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLTRRQALGAGAAAGLAVVGAAPPAPAAPATAAAPAAVRRRTV
                     HGTPQPFDEVYLGRRIQGGPSHSGGHHAHHADGWIVRIDGQELHVMRNADGTWISVVNH
                     YEPQATPRALARAAVLELQGASLVPLDLA"
     gene            5422..6249
                     /locus_tag="OGH68_RS33780"
                     /old_locus_tag="OGH68_33780"
     CDS             5422..6249
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038020.1"
                     /locus_tag="OGH68_RS33780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_33780"
                     /product="tyrosinase family protein"
                     /protein_id="WP_264249291.1"
                     /transl_table=11
                     /translation="MTVRKNQAALTTAEKRRFTDAVLELKRTGRYDAFVTTHNGFIMSD
                     TDHGPRTGHRSPSFLPWHRRFLLDFEQALQSVDPSVALPYWDWTVDRTPASSLWAADFL
                     GGTGRSRDGAVMDGPFAAAAGNWPITVRVDGRDHLRRSLGARGLQLPTRAETDSVLAMP
                     VYDMPPWNSASDGFRNHLEGWRGVNLHNRVHVWVGGQMATGVSPNDPVFWLHHAFIDRL
                     WTQWQTRHPDSAYAPAAATSDVVDLHDPMRPWNDVTPADMLDHRPHYTYDTAA"
     misc_feature    5462..5476
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.33"
                     /tool="antismash"
     gene            complement(6274..8613)
                     /locus_tag="OGH68_RS33785"
                     /old_locus_tag="OGH68_33785"
     CDS             complement(6274..8613)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955710.1"
                     /locus_tag="OGH68_RS33785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_33785"
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="WP_264249294.1"
                     /transl_table=11
                     /translation="MHTPHDPYVRVRGAWEHNLRGVDVDIPRDALVVFTGVSGSGKSSL
                     AFGTVYAEAQRRYFESVAPYARRLIHQVGAPKVGEITGLPPAVSLEQRRSSPSSRSSVG
                     TVTTLSNSLRMLFSRVGDHPEGAPRLDSDAFSPNTAAGACPKCHGLGRVHSTTEELLVP
                     DPSLSIREGAIAAWPGAWQGKNLRDVLDALGHDVDRPWRDLAQQDRDWILFTDEQPVVT
                     VHPVREAGRIQRPYQGTYMSARRYVLHTFSDSRSRTLRARAERFLTSEPCPVCAGRRLR
                     PESLAVTFAGRTIAELAALPLTALAGVLREGDGGETARVLTADLLARVATVTELGLGYL
                     SLDRATPTLSSGELQRLRLATQLRSGLFGVVYVLDEPSAGLHPADTEALLVVLDRLKAG
                     GNSVFVVEHHLGVVRHADWLVDVGPLAGEHGGRVLHSGPPEQLAGVSESVTRRFLLEAG
                     PPPVRTPREPSGHLTLGPVTRHNLRGLTTRLPLGVLTAVTGVSGSGKSTLVGSVTEEHP
                     GVGRLVTVDQKPIGRTPRSNLATYTGLFDVVRKVFAATGEARERGYRAGRFSFNVSGGR
                     CETCQGEGFISVELLFLPSTYTPCPACGGARYNEETLQVRHRGLNIAEVLDLTVEGAAD
                     FLTGTPAAERSLRALLDVGLGYLRLGQPATELSGGEAQRIKLATELQRLRRGHTLYVLD
                     EPTTGLHPADVEVLMRQLHGLVDAGNTVVVVEHDMDVVAGADRVIDMGPGGGDEGGRIV
                     ASGSPAEVARAAGSRTAPYLAEALGR"
     gene            complement(8642..9658)
                     /locus_tag="OGH68_RS33790"
                     /old_locus_tag="OGH68_33790"
     CDS             complement(8642..9658)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007451465.1"
                     /locus_tag="OGH68_RS33790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_33790"
                     /product="MsnO8 family LLM class oxidoreductase"
                     /protein_id="WP_264249295.1"
                     /transl_table=11
                     /translation="MSSVTASTRLSVLDRSRTREGYDAPAALRDTVSLARHAEALGYHR
                     FWVSEHHGVPGVAGSAPTVLAAAVAAATTSIRVGTGGVMLPNHQPLVVAEQFGVLESLF
                     PGRVDMGLGRSVGFTDGIRRALGREKKDAEDFAVQLEELLGWFTGGQTAHPHVRARPSE
                     GLRVPPYLLATGEGARIAARAGVPLVIGDLRGRDRLLTAVDGYRREFRPSRWAERPYVV
                     VAGTVAVAGTEEEAHRLLMPEAWSMAYSRTHGTFPPLMPPERIEALEMTAKERDLYESG
                     LRGHIAGTEEQVAEALGTAVKESGADEVLVTTSTYDRAALLDSLRRLARITGQSPTG"
     gene            9719..10216
                     /locus_tag="OGH68_RS33795"
                     /old_locus_tag="OGH68_33795"
     CDS             9719..10216
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996016.1"
                     /locus_tag="OGH68_RS33795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_33795"
                     /product="hypothetical protein"
                     /protein_id="WP_264249297.1"
                     /transl_table=11
                     /translation="MTHSSRPLAVFDLDGTLSDAGHRQHLLERKPRAWDAFFAAAPYDP
                     PLAEGVALCLEAAKECEVMYLTGRPERCRADTLDWLAAQGLPEGRLFMRRNDDRRPARR
                     TKLEILRRLARDREVGMLVDDDELVCQDAERAGFRVVRAARWGASSTTPVMRDAQEREG
                     RT"
ORIGIN
        1 gcggcgaggg cgtctacctg gacttcgccg acgccatcgc gcggatgggc agggccaagg
       61 tcgaggagaa gtacggcaac ctcttcgaga tgtacgagcg gatcaccgcg gagaacccgt
      121 acgaggtccc gatgcggatc taccccgccg tccactacac gatgggcggg ctgtgggtcg
      181 actacgacct gcagaccacg atccccggcc tcttcgcgat cggtgaggcc aacttctccg
      241 accacggcgc caaccggctt ggcgcctccg ccctcatgca gggactcgcc gacggctact
      301 tcgtcctgcc gtccaccatc aacgactatc tcgcccgcgg cggcctcgac gccgtggacc
      361 cctccgatcc ggcggtcacc gaggccgtcg ccgacaccga ggaccggctc aacctgctgc
      421 tggccgtcga cggcgaccga acgcccgact cgttccaccg cgagatcggc gaactcatgt
      481 gggacttctg cggaatggcg cgcaccgacg agggcctgcg caaggccctg gaccggatcc
      541 cgcagatccg ggaggagttc tggcgccgga tcaaggtgcc gggcaccgga gcccagttca
      601 accagtcgct ggaaaaggcc aaccgcgtcg tcgactacct ggagctcgcc gagctgatgt
      661 gcctcgacgc cctgcaccgc gccgaatcct gcggcggcca cttccgcgag gagtcccaga
      721 cccccgacgg cgaggccgcc cgcaaggacg aggagttcgg ctacgccgcg gcctgggagt
      781 tccggggcac cggcgagccg ccggaactcc acaaggaaga cctcgtcttc gagtacgtcc
      841 accccaccca gcggagctac gcatgaagct caacctgcgc gtctggcgcc agcagaaccc
      901 ggacgccgaa ggcgccatgg ccacctacga ggtcgacggc atctccccgg acatgtcctt
      961 cctggagatg ctcgacaccc tcaacgagga cctcatcctg cgcggcgagg aacccgtcgc
     1021 gttcgaccac gactgccgcg agggcatctg cggtgcctgc tccctggtca tcaacggcga
     1081 cgcccacggt ccggaacgca ccaccacctg ccagctgcac atgcgctcct tccgcgacgg
     1141 cgacaccatc gacgtcgaac cgtggcgggc ctcggccttc cccgtcgtca aggacctcgt
     1201 ggtggaccgc tcctccttcg accggatcat ccaggccggc ggctggatca gcgcccccac
     1261 cggctcggcg cccgaggccc acgccacgcc cgtgcccaag cccgacgccg acttcgcctt
     1321 cgagcacgcc gagtgcatcg gctgcggagc ctgcgtggcg gcctgcccca acggctcggc
     1381 gatgctcttc acctcggcca aggtcaacca cctgggcgtg ctgccccagg gggctcccga
     1441 gcgggagacc cgggtgctcg acatggtcgc ggccatggac gacgagggct tcggcggctg
     1501 caccctcacc ggggagtgcg ccagcgcctg cccgaagggc attccgctgc cgtccatcgc
     1561 cgcgatgaac cgggagtggc tgcgggcgac ccggaaggtc aggcggtagg ccgtagatcg
     1621 gcgccgtaca ccgtcgcgta gtcgggcacg acgatccggg aggcggggga cagccggcgg
     1681 acctcggcgg tgaacgcgtc gaggtccatc gccggatccc ttcggggcgg cgcgctgaga
     1741 ggctcctcga agttgtccca gtgcacgggg acgaccgtcc ccgggttccc gagcgtgctc
     1801 agcagccgtg gcagatagcg gtgcgtcgac cggctcgagg gcgtcgcggc catcagcacg
     1861 tcgggccgca gaccggccgc ggaccgttcg tcgaagtcgc tcgcgcccat gaggaagaac
     1921 gagggcccgt cggcgacggt cacctggaag gcgagcgtgt cgccctccgg gagatcggag
     1981 accgtccgag gcgccgggcg cggcggggcg tggagcgtgc ccggcgcgaa gtaggaccac
     2041 ttggcgttgc ggctgtgccg ggaggccacc acctcgaccg tgaaaccgtc gaagtcgagc
     2101 acctcaccgc ccttcaccac actgatctgc ccggcgtcca cgccgagcgc ccgcagcacg
     2161 tgatacgtcg tctccgtgcc gatgacccgg gcgcccgtcg acgtcgcgat gcagggcacg
     2221 tcgcccacat ggtcccaatg ggtgtggctg acgagcacca gttcggggcg gcccgcgtgc
     2281 cgggccacca gctcctcgtc gctcctcagc cgggtgtccg ggtcgaagcc cttcggcccg
     2341 aacagtccgg tcgggaagcg ggtgatgtac gggtcgaaga gaacggtccg gccgccgaca
     2401 ccgacgccga tgcgccagcc ggacgtgccg agccagcgca gggtggcagc gtcggggcgt
     2461 accgcgcccg acgcgctccc tgccgagccg accggtgccg cgtccgcgcc gaccggtgcc
     2521 gcgtccgggg cggcctgcgc cgcgccggcc gccgccggca gcagcggagc cgccgcgccc
     2581 acggccgcgc cgcgcagcag ggtccgtcgt acgaaggtcc gccgtccgtc gtcgtgccgc
     2641 atgttcgtgt gttcgctcat gggacagaga agatcagccc caggcggcgg gcgtccaaga
     2701 cccggccgcc gcacgactca taccgccgga cgcatgaggc ctggtcaaag gggctgcccg
     2761 gtcccggtgc cgcgcagcag atccaccgcg gtccgcgccg ccgtaccgat ggccacgtcc
     2821 gtctgcgtat ggttcgcgac gaggtccggg gtgcgggcga acacggcgac cgcgtaccgc
     2881 ccgccgtccg ggaactcgac cacacccacc tcgttgtgca gcccgggcag cgtcccggtc
     2941 ttggccgcga cgcgcacgcc gtcgccgaac ccggcggcca gccggtgccg gaacacctgc
     3001 cgggccatca ggtcccgcac ctgggcacac gcctgcggcg ggccggcctc gtcacgccac
     3061 accatccgca gcagccgcgt catctcgcgc ggtgtgctcg cgttcgtacg ggcagggtcg
     3121 tggacgccga gcgcccgcac ctgctcgggg gacagggtcg ggaacaccgc ggcgaactcc
     3181 cgctcgtctt gggcccccac ctcggcgagc atcgactcca gcaactgcct cgggccgccc
     3241 acgatccggg tgcccaccag accgagttcc gcggcgagca gcgccacggt gtccgccccg
     3301 acccgttcca tcagcaggtc ggccgccgtg ttgtcactca ccgccatggc gaagtgcgcg
     3361 aggtcgcgca gcgaaagctc cacgtcgtcc aggcagccgc cggtgcccca gccaccgagc
     3421 ctgcggtccg cgctcacccg tacccgctcc cgggggtcga gctgaccggc agccgcctgc
     3481 cgggcgaact ccagcaccag cagcaccttg aacacggagg ccaccaccac cggttcgtcg
     3541 gggcggcacc cgacctcccc cgggccgtcg atgtccacgg cgtgcagcgc ccccgcggcc
     3601 cccgccgcgg cgaacaccgc acccagccgc tcctccaccc gcatccggat caacactccc
     3661 gcctgtcgcc taaggtcttc cccgtggatc tcctgcgcca cttgcgtatc ttcgtcgccg
     3721 tcgccgacga gttgaacttc gggcgggcag ccgaacggct cgggatggcc cagcccccgc
     3781 tgagccgtgc cgtgcgcaga ctggaggacg acctcggggc cgaactcttc gaccgctccc
     3841 gccggcaggt gcggctcacc ccggccggct cggtgctcct cgacgaggcg agggagctgc
     3901 tggcacgcga ggagcgtacg agagcgctcg tccggcgcgc ccgcgacggc gacctcggga
     3961 cgctgcgcgc cggcgtgccg cccgacacct cggccgcggt gctctccgcg ctcctcgtcc
     4021 ggtgcgacga gcgcggactg cgggtcgatc tccaggaggt gacgacggac gagcagctgc
     4081 ggctgctggc ctccgggggc ctggacacag ggctggtgca tcagccggtc gacgccacgg
     4141 aactggagtt gggaccggag gtccgtatcg agctcggagt ggtgctgccc cggacatcgc
     4201 ctctcgcgcg gctgccggag gtcgccgtgg gcgacctggc ggggcacgac ctggtcctct
     4261 tcccccggac gtcggcgccc ggctggtacg acacgacgct cgacgtctgc cggcgggagg
     4321 gcttcgtccc cggcaggatc aggcacgcac gcaacccgga gttcctcatc ggcctggtga
     4381 cggcgggtca cggagtcgcc ttcgaccagg ggacggtcgc ccgcaaggag cccagggccg
     4441 cctggcggcc gctcgtcggc cggccgctcg cccagcggat ctgtgccgcc tggccccgcc
     4501 ggtcgccgca cggcgccgcg gcccgggagt tcgccgctgt cgcggcggag gtgctcgggc
     4561 gcgaccgtac ggcggtgccg tacggcgggg gaggggaggc ggggccacgg ccctggtcgg
     4621 tggtgtacgg ctgaggggcc gtcacggccg tcgagcggac cggggccggg ggcggtccag
     4681 gagcggggcc ggagcagaac cggcatatgt tccggtcatg tttgcggcgt gagaatgtgc
     4741 atggattctg tgcccgcacc gaagaacgtc cgttgagggc ccgccttcag ggcggaatat
     4801 tcgcttcctg tggtacccgc aggccgcgtg atcgcaagat caacttctgt tcaattccgt
     4861 acctctcgcg tcgagttgtc catttcgcgg ccaagcggcc cccgccgttt accgggcgtc
     4921 tcgcggatcc aggtaggcat gtccgcgggc ggtgccgacc acaccgccgt acggaccaca
     4981 gcacctctgg gggatcagtc atgtcccgac tcacccgccg tcaggccctg ggcgccggcg
     5041 ccgccgcggg cctcgccgtc gtcggcgccg cgcctccggc acctgccgca cctgccacgg
     5101 ctgccgcacc ggccgccgtg cgacggcgca ccgtccacgg cactccgcag cccttcgacg
     5161 aggtctacct cggccgtcgc atacagggcg gcccgtcgca cagcggcggc caccacgcac
     5221 accacgcgga cggctggatt gtgcggatcg acggccaaga actgcacgtc atgcgcaacg
     5281 ccgacggtac gtggatcagc gtcgtgaacc actacgagcc gcaggccacc ccgcgggccc
     5341 tcgcgcgcgc cgcggtcctg gaactccagg gcgcctccct cgtccccctc gacctcgcct
     5401 gacccgggag cagcccgcac catgaccgta cgcaagaacc aggccgcgct caccaccgcc
     5461 gagaagaggc gtttcaccga cgcggtgctc gaactcaagc ggaccggccg ctacgacgcc
     5521 ttcgtcacca cccacaacgg tttcatcatg agcgacaccg accacgggcc ccgcaccggc
     5581 caccggtcgc cgtcgttcct gccctggcac cgcagattcc tcctcgactt cgagcaggcg
     5641 ctgcagtccg tcgacccgtc cgtcgccctg ccgtactggg actggacggt cgaccgcaca
     5701 cccgcctcct cgctctgggc ggccgacttc ctcggcggca ccggccgcag ccgcgacggc
     5761 gcagtcatgg acgggccgtt cgccgccgcg gccgggaact ggccgatcac cgtgcgggtg
     5821 gacggccgtg accatctgcg gcgctcgctc ggcgcccgcg gcctccaact gcccacccgg
     5881 gccgagaccg actcggtcct cgccatgccc gtctacgaca tgcccccctg gaacagcgcc
     5941 tcagacggct tccgcaacca cctcgaaggc tggcgcggcg tcaacctcca caaccgggtc
     6001 catgtctggg tcggcggtca gatggccact ggagtctccc ccaacgaccc cgtgttctgg
     6061 ctgcaccacg ccttcatcga ccggctctgg acgcagtggc agacccgtca cccggactcg
     6121 gcgtacgccc cggcggccgc cacgtccgac gtggtggacc tgcacgaccc gatgcgcccc
     6181 tggaacgacg tgacacccgc cgacatgctc gaccacagac cgcactacac ctacgacacc
     6241 gccgcgtagc ccccgccgcg ggggcgacgg agcctatcgt ccgagcgcct cggcgagata
     6301 cggcgcggtg cggctgcccg ccgcccgcgc cacctcggcc ggggagccgg acgcgacgat
     6361 gcggccgccc tcgtcacccc cgcccggacc catgtcgatg acccggtccg cgcccgccac
     6421 cacgtccatg tcgtgctcga ccaccaccac cgtgttccct gcgtcgacca ggccgtgcag
     6481 ttgacgcatc agtacctcca cgtcggcggg gtgcagcccg gtcgtcggct cgtcgagcac
     6541 gtacagggtg tgaccgcggc gcaggcgctg cagctccgtg gcgagcttga tccgctgggc
     6601 ctcaccgccc gacagttcgg tcgccggctg gccgagccgc agatagccga gccccacgtc
     6661 gagcagcgcg cggagactgc gctcggccgc cggggtcccg gtgaggaagt ccgccgcgcc
     6721 ctcgacggtc aggtccagca cctcggcgat gttcaggccc cggtgcctca cctggagcgt
     6781 ctcctcgttg tagcgggcgc caccgcaggc cgggcagggc gtgtacgtgc tgggcaggaa
     6841 cagcagctcc accgagatga atccctcgcc ctgacaggtc tcgcaccgcc cgccggacac
     6901 gttgaacgag aaccggcccg cccggtaacc ccgctcccgg gcctccccgg tggcggcgaa
     6961 caccttgcgg accacgtcga acaggcccgt gtacgtggcg aggttggagc gcggcgtacg
     7021 gccgatcggc ttctgatcga ccgtcaccag acgtccgacg cccgggtgtt cctccgtgac
     7081 ggagccgacg agggtggact tccccgagcc cgacacaccc gtcaccgcgg tgaggacccc
     7141 gagcggcagg cgcgtggtga gcccgcgcag attgtggcgg gtcaccggcc ccagcgtgag
     7201 gtggccggac ggttcgcgcg gtgtccggac gggtggcggc ccggcctcca ggaggaaacg
     7261 ccgggtgacc gactcgctca ccccggccag ctgctccgga ggaccgctgt gcaggacccg
     7321 cccgccgtgc tcgcccgcca gcggcccgac gtccaccagc cagtccgcgt gccggaccac
     7381 cccgaggtgg tgctccacca cgaacaccga attgccgccc gccttgagac ggtcgaggac
     7441 gacgagcagc gcctccgtgt cggccggatg cagtcccgcc gacggctcgt ccagcacgta
     7501 caccacgccg aacagtcccg agcgcagctg ggtcgccagc cgcagccgct gcagctcacc
     7561 gctggagagc gtgggagtgg cccggtccag gctcagatag ccgaggccca gttcggtcac
     7621 cgtggcgacc cgcgccagca ggtccgccgt cagcacccgc gccgtctcac cgccgtcccc
     7681 ctcccgcagc actccggcca gggctgtcag cggcagcgcc gcgagctcgg cgatcgtacg
     7741 gcccgcgaag gtcaccgcga gcgactccgg ccgcagcctg cggcccgcac agaccgggca
     7801 gggctcactg gtcaggaacc gctccgccct ggcgcgcagc gtccggctcc tggagtccga
     7861 gaacgtgtgc agcacatagc gccgggcgct catgtacgtc ccctggtagg ggcgctggat
     7921 gcggcccgcc tcccggaccg ggtgcacggt gacgaccggc tgctcgtccg tgaagaggat
     7981 ccagtccctg tcctgctgcg ccaggtcccg ccagggccgg tccacgtcgt ggccgagggc
     8041 gtccagcaca tcacgcaggt tcttgccctg ccaggcgccg ggccaggcgg cgatcgcccc
     8101 ctcgcggatc gacagcgagg gatcgggcac cagcagctcc tccgtggtgc tgtgcacgcg
     8161 gcccaggccg tggcacttgg ggcaggcgcc ggcggccgtg ttcggcgaga aggcgtccga
     8221 gtcgagacgc ggtgcgccct cggggtggtc gccgacccgg gagaacagca tgcgcagcga
     8281 gttggagagc gtggtgaccg tccccacgga ggagcgcgag gagggggagg agcggcgctg
     8341 ctccagcgac accgcgggcg gcagaccggt gatctcaccc accttcggcg cgcccacctg
     8401 gtggatcagc cggcgggcgt acggcgcgac ggactcgaag taccggcgct gggcctctgc
     8461 gtagacggtg ccgaacgcca gcgaggactt gccggagccg gacacgccgg tgaacacgac
     8521 cagggcgtcg cgcgggatgt ccacgtcgac gccgcgcagg ttgtgctccc aggcgcctct
     8581 gacgcgcaca tacgggtcgt gaggggtgtg cataacggac gattctaggt gtcggcgctg
     8641 gtcagccggt cggcgactgc cctgtgatcc gggccagacg ccgcagcgag tccagcagcg
     8701 cggcacggtc gtaggtgctc gtcgtgacca gcacctcgtc ggcgccgctc tccttcaccg
     8761 ctgtccccag cgcctcggcg acctgctcct cggtgcccgc gatgtggccc cgcaggcccg
     8821 actcgtacaa gtcccgctcc ttggcggtca tctccagggc ctcgatccgc tccggcggca
     8881 tgagcggcgg aaacgtcccg tgggtgcggg agtacgccat cgaccaggcc tccggcatca
     8941 gcagccggtg cgcctcctcc tcggtcccgg cgaccgcgac cgtccccgcg acgaccacgt
     9001 acggccgctc ggcccaccgg gacgggcgga actcccgccg gtagccgtcc acggccgtca
     9061 gcagccggtc ccggccgcgc agatcaccga tgaccagcgg cacgccggcc cgcgccgcga
     9121 tccgcgcgcc ttccccggtg gcgagcaggt acggcggcac ccggaggccc tcggaggggc
     9181 gggcgcggac gtggggatgc gccgtctgcc cgccggtgaa ccagccgagg agttcctcca
     9241 gttgcaccgc gaagtcctcg gcgtccttct tctcccggcc cagcgccctg cggatgccgt
     9301 cggtgaagcc gacggaacgg ccgaggccca tgtcgactcg gcccgggaag agcgactcca
     9361 gcacgccgaa ctgctcggcg acgaccagcg gctggtggtt gggcagcatg accccgccgg
     9421 tgcccacgcg gatcgacgtg gtggcggccg cgacggccgc cgccagcacg gtgggcgccg
     9481 aaccggcgac gccgggcaca ccgtggtgct ccgagaccca gaaccggtgg tagcccaggg
     9541 cctcggcgtg ccgggcgagg ctcacggtgt cgcgcagcgc ggcgggagcg tcgtacccct
     9601 cccgggtgcg ggagcggtcg agcacggaca ggcgggtcga tgcggtcact gagctcacat
     9661 accggttcaa cgctcacggc ccgccgggat tcccgttccc cgctctaggg tgggcggtgt
     9721 gacacacagc agcaggccgc tggccgtatt cgacctcgac gggacgctct ccgacgccgg
     9781 gcaccgccag catctgctgg aacgcaagcc gcgcgcctgg gacgccttct tcgccgctgc
     9841 cccgtacgac ccgccgctcg ccgagggcgt ggcgctgtgc ctggaggccg cgaaggagtg
     9901 cgaggtcatg tacctcacgg gccgaccgga gcggtgcagg gcggacaccc tggactggct
     9961 cgccgcccag gggctgccgg agggccgcct cttcatgcgg cgcaacgacg accggcggcc
    10021 ggcccgcagg accaaactgg agatcctgcg gcggctcgcc cgcgaccggg aggtcggcat
    10081 gctggtcgac gacgacgaac tggtctgcca ggacgcggag cgcgccggct tcagggtggt
    10141 acgggcggcg cgctggggcg cgtcgagcac gacacccgtg atgcgggacg cgcaggagcg
    10201 cgagggccgc acctgaggcg gccgtcccgc gagggcgctc gggcggtcag tcgccgtcct
    10261 cgagacggaa gcccaccttc agaccgacct ggtagtgctc gatctgcccg tcgacgatgt
    10321 gaccgcggac ctgcgtcacc tcgaaccagt cgaggccccg cagcgtctgc gacgcccggg
    10381 tgatcccgtt tcggatggcc tg
//
