LOCUS       NZ_CP107567            11368 bp    DNA     linear   CON 18-NOV-2023
DEFINITION  Streptomyces peucetius strain NA0869 chromosome, complete genome.
ACCESSION   NZ_CP107567
VERSION     NZ_CP107567.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces peucetius
  ORGANISM  Streptomyces peucetius
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8050611)
  AUTHORS   Zhao,E. and Ge,H.
  TITLE     Cytochrome P450 Catalyzes Benzene Ring Formation in the Biosynthesis
            of Trialkyl-Substituted Aromatic Polyketides
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8050611)
  AUTHORS   Zhao,E. and Ge,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2022) School of Life Sciences, Nanjing University,
            No. 163 of Xianlin Avenue, Qixia District, Nanjing, Jiangsu 210033,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: unicycler(0.4.8) v. v. 3
            Assembly Name                     :: NJU_NA0869
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/18/2023 06:49:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,216
            CDSs (total)                      :: 7,126
            Genes (coding)                    :: 6,825
            CDSs (with protein)               :: 6,825
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 303
            CDSs (without protein)            :: 301
            Pseudo Genes (ambiguous residues) :: 0 of 303
            Pseudo Genes (frameshifted)       :: 144 of 303
            Pseudo Genes (incomplete)         :: 227 of 303
            Pseudo Genes (internal stop)      :: 22 of 303
            Pseudo Genes (multiple problems)  :: 85 of 303
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:23:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6586120
            Orig. end                         :: 6597488
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP107567.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from IFB-NA0869, Nanjing
            University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..11368
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="23"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11368
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11368
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6368](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6368
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            1561..2440
                     /locus_tag="OGH68_RS29830"
                     /old_locus_tag="OGH68_29830"
                     /pseudo=""
     CDS             1561..2440
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452729.1"
                     /locus_tag="OGH68_RS29830"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_29830"
                     /product="ABC transporter ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTTATTPSAAGAAAENAARAGTLRAEGVRFGYGGREVLAGVDLDV
                     GAGECVALVGLNGCGKSTLLRLCAGLLRPAAGRVSLGGDDLARLSRRSTARRVALLHQS
                     APAVPGMTVRQLVRQGRYAARGPLGMLRDGDDAVCSRAMADVGVAPWADRPVDSLSGGE
                     RQRVRLAMALAQDTRVLLLDEPTTYLDLRHQLEVMQTVVRLREERGLTVVMVLHDLGHA
                     ARFADRIVALRAGRVAADGPPAEVVTPVLLAEVLGVAGRVGLDPEGGWPVCYPDHPLPV
                     TEPLAK"
     misc_feature    2437..2439
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            2508..2645
                     /gene="amiA"
                     /locus_tag="OGH68_RS29835"
                     /old_locus_tag="OGH68_29835"
     CDS             2508..2645
                     /codon_start=1
                     /gene="amiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129278.1"
                     /locus_tag="OGH68_RS29835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_29835"
                     /product="streptamidine family RiPP"
                     /protein_id="WP_264250350.1"
                     /transl_table=11
                     /translation="MEQYKVFSPIAEQGQLAHLSATHSNALVENPFDDNAAAVETDSDK
                     "
     gene            2726..3514
                     /locus_tag="OGH68_RS29840"
                     /old_locus_tag="OGH68_29840"
     CDS             2726..3514
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018847810.1"
                     /locus_tag="OGH68_RS29840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_29840"
                     /product="hypothetical protein"
                     /protein_id="WP_264248278.1"
                     /transl_table=11
                     /translation="MATVRLAPGVALVTVPGHGLAVRTPDGAFLRVDTGAADQDALVAQ
                     LTRGCGDDTELARLTAAFADAGFLARTDDIRAPLNGRTVVLLGDPVLTEPLARFVRAEG
                     GEVRHAGPDDLGGTGPSTAVVWCLDSPVPNGLWDEADRLPARGTCWLRCHREGATVWTE
                     PFAAATGDVTSADVRLRRLAATPAHRELAAYWAGSRTDDTGPAHNAASAALTASLITAD
                     LIAWAAGRPGGRRLRRVDVRDLTVTEHPVLPVPAVAPLDR"
     gene            3511..5004
                     /locus_tag="OGH68_RS29845"
                     /old_locus_tag="OGH68_29845"
     CDS             3511..5004
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059074.1"
                     /locus_tag="OGH68_RS29845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_29845"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_264248280.1"
                     /transl_table=11
                     /translation="MRAATVPVPGARLATAVQLPDGDGPFPAVVIRTPYGQVGHRDEAR
                     AWAARGFAAVVQDVRGRHGSTGDWHPYRHEEADSAATLRWVRGHRWSDGRVVAAGASYA
                     AHCALAATAAVESADRPDAVIAAVPALGLAETAREAGGVERLAARAGWWAAHGDRPDSD
                     ATALDKALARDPRLLEHLPLTTFPERLGRALPSWPALWDASRRPRPRPRAPLPLLAVGG
                     TRDPFADDTLRLWAEWAGPARLLLGPWGHGLTSEPAPEARPGHRIRLGELYVTWARAAL
                     TGALGRERRGAVALGDSEHWYPAAPDTGERTTWPFGVPSGLRLLRGGTFVADPQSPVRS
                     DDLNVPTGEAPDRALLVTPPLPRPLDLLGTAEARLCATADTPTADWAVRVVALDPAGRA
                     APLATGVVRRSGPPGAPAAFRVPLGPVARRLPAGTRLRVEVAGHHFPAHARNPHTGEDP
                     VRATRLIASRRTVRTAGSGLLLPVVRGSRPVDPVQETRS"
     gene            5001..6368
                     /locus_tag="OGH68_RS29850"
                     /old_locus_tag="OGH68_29850"
     CDS             5001..6368
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059075.1"
                     /locus_tag="OGH68_RS29850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_29850"
                     /product="YcaO-like family protein"
                     /protein_id="WP_264248282.1"
                     /sec_met_domain="YcaO (E-value: 3.6e-46, bitscore: 157.1,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTLTLDSLVDPVCGLIRGVEPVPHPAGAPPRYTAMTADVGDAR
                     RFGAWPADRVSLGTTFGDPEGARIAAVAEAVERYCGNRLPPPGHPGAPRRATAAELVAE
                     GGTVYGPGELPAYADWQYARPGFEYRRLTADTPALWARGQENGEECWAPVALTHLNWRQ
                     GDLRSLPRTHHLNYAGIATGQGFDDAVERGLLEVVERDALELWWHLDGPARGIDPASVP
                     GLTRDLDGCDLEVSIVEMPSEFAPCMAALVHDPARGIHAAGFACRYDPAEAARKAVLEA
                     VHTWVFTQGATDADGWVFRAIDAGMLARGLYLDHRADRRYLDDCGTDFRAVRDLGAHVQ
                     VWLDPRMAPLAGRFTRPALGVVPVDEVAAGSRAVLDERLAAGGHRVITLDLTTEDVAET
                     PLRVARVLVSGLVPNAPAAFAYLGCPRFGHAARARGWRTEVPQSASDFTLAPPPHM"
     gene            6376..7725
                     /locus_tag="OGH68_RS29855"
                     /old_locus_tag="OGH68_29855"
     CDS             6376..7725
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020571982.1"
                     /locus_tag="OGH68_RS29855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_29855"
                     /product="hypothetical protein"
                     /protein_id="WP_264248284.1"
                     /transl_table=11
                     /translation="MESSVTRALTLARSAQAPGPDFPAGPASVPLPGEALPVPARLDRM
                     LRLSLAGRRLRPVPSAGALHPVDTYLLVGAGCGLPPGVHVYDPARHRLHRCGPAPCPAP
                     PGAVAVLGVTARRTVSHYGHRAWPLVLLDVGHAAAALALAGAHAVCLDADGGLLSGASG
                     APVALAAVRLTADAAPDGLVRWAARATGGRIPAPEGPEVLRTAVAVLAELAAAGGKSGT
                     WRAATGPLLPDSVLLSRRSAPPGFHDLPPHEALARVLAAARAASPDGLGWTLAVSGPRP
                     GLLTAPTPAPPAESTVPGSAAAPAHRTAPADGSLPPLRRLGSSPADPFGTAPAAGTVPP
                     LRRLASGDVLPTLAHWAAGQGWIAGAGAVLLAHGCPSGATAAQVRHCHLAAGHGVAHAQ
                     AAATALGIHSRPVGSWQGADLGAALGGPAGRDWVVHGLALGRTTQGDEPS"
     gene            7722..9464
                     /locus_tag="OGH68_RS29860"
                     /old_locus_tag="OGH68_29860"
     CDS             7722..9464
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955801.1"
                     /locus_tag="OGH68_RS29860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_29860"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_264248286.1"
                     /transl_table=11
                     /translation="MMLHPELLRAARTARRPLLTATALLAAVAATHLAQAVLLALVLAR
                     IARGDTGGAPLPLLLGAVLTAVLVRAVLGRLQRRVAVSAGAAVRTGLRDRLLERLGRTG
                     PPQHAEARAGAVRATLVDGVEGVDAYISRYLPQLLITCAVPPLLLIAVAAVEPWTVLAL
                     GPALVVALFAPRWWDKLLERRGQQHWGAYEALSADYLEALQGMPALRAAGAVGRTRARL
                     EERSRALHRATVAKLRVSLVDTGITDLAVQGGTVAAALVACASAASGHATPTATYLVLM
                     LASECFRPVRDLSREWHSGYLGVSAADGIAELRTAEGGVPDTGRTVAAWHAAPEVRFED
                     VHFTHPGGRGPALGGVSFTARPGRVTAVVGPSGAGKSTLLGLLLRRADPDEGRVLVNGV
                     DTTAYTLPSLRRGIAVVSQETYLFHATVAENLRLGAPGASDTALHDAARTAGIHDEIVG
                     LPDGYDTLVGERGATLSGGQRQRLALARALLADAPVLVLDEATSAVDEHREARIVEELL
                     RAARGRTCLVVAHRLDSVREADTIVVLDGGRVDAVGGHAGLLAGDGVYARLVAAGHTDT
                     ERAA"
     gene            9461..11170
                     /locus_tag="OGH68_RS29865"
                     /old_locus_tag="OGH68_29865"
     CDS             9461..11170
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015613010.1"
                     /locus_tag="OGH68_RS29865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_29865"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_264248288.1"
                     /transl_table=11
                     /translation="MNPERGALRALLPVLAAHRAMTLRTFCAALAGQASLVALVTLTAH
                     TVGTAVVERRAPGAGTVAALLALVAVRALATWREMDLSHDLAYRVLAELRIRVFDGLAR
                     SAPARIAGRRSGDLASAALGDVEALEFFYAHAVAQLAASGVVFGGGTVALGLLDPWLLL
                     AVLPVAALLTLAPVLESRGRAARGARTRAAAADLSAETVETVDGLRELLTFGALDARRE
                     RLRAHGRRLGDAQRAEQAWEADASAVRDLLVVVAVLGVVLAAAHTFAGAWAPAAMALAL
                     GVLAPVADSAAALGQAGGLRAAAARVGAAVRAPAGAPEPAAPRGLPTGPLGLRLRDVRF
                     DYGGRAVLDGVDLTVRPGETLALVGVSGAGKSTCAHLVARFWDPASGTVELVPETGPPV
                     DLRDLAEADLRAAVAVVGQDAPLFHGTLADNLRLASPTATATDDELAAVARRTGVDRIA
                     DGYDTLVGERGTTLSGGQRARIALARALLTRPRVLVLDETTANLDTEGDAAVSAALRDG
                     SPSRTTLLIAHRPSTIRRADRIAVLESGRVVQTGTWDQLTEQGGAFARVLTR"
ORIGIN
        1 ggtcctcggc ggcgccggtg acccggccgc gcgccacatc gtgctccagc tccggctgcc
       61 cagggcactg gtcgcactcg tcgccggcgc gagcctcgga ctcgcgggca tggtcctgca
      121 gtccgccctg cgcaacccgc tcgccggacc cgaggtcacc ggcgtcaccc cgggcgcggt
      181 gctcggcgcc gtggccgcca ccggtctcgg gatcgcggga tggcggtcgc cgacggccgt
      241 ggtcgtcgcg gcgtgcgtcg gcgggttcgc gggggcgggg ctgctgtggc tgctgaccgg
      301 ccgcgagaaa cacgatcccg cgcagacggc cgtgcacggg gtgctcgtgt cggcggtcct
      361 gtccgggctc acggcgatgg tgctgctcgt cgcgcccggc gaactcggca gcgtggtgca
      421 gtggctggtc ggctccacgg aggggcgggt gtggcagcac tgggtgctgc tgtggccctg
      481 ggcggcggtg tgggccgtgg cggcgtacgc gctggccgcg ccgctcacgc tgctgcgctg
      541 cggtgacgaa caggccgccg cggccggtct cggcaccggc cgcgcccgcg tcgccgcgct
      601 cgtctgcgcc gtcgccctga cggccggggc ggtctcggcg gtcggcgcgc tgggcttcgt
      661 cggactgctc gtcccccacc tcgcgttcgc cgtcttcggc gcggacctcc gccgcgccct
      721 gcccggcgcg gcgctcctcg gcgcggcggt cgtgacgggc gccgacgcgg gcgcgcagtg
      781 gctttcgcgg gcgctggccg gtgcgctgga catggaccgg ctgtccgtcc cgacgggcgc
      841 gctgacgacg tgcgtcggag cggcgctgct gctcggggtg gcgcggcgcg cgggggcggg
      901 ggcgggggag tgacggtggg gtgggcgggt gcgggcgggg tccgctgcgc ggggcctgtc
      961 ccccctcccc gccccttccc gaaaccgggg ctccgcaccg gggctctgcc cccgggaccc
     1021 accggggatc cgcccccggg ttccgcaccc gggctccgcc cccaggcccc accggggagc
     1081 cgcaccgggg ctccgccccc aggccccacc ggggagccgc accggggctc cgccccgggc
     1141 cccactgggg atccgccccc gggctttgcc ccgggcccca ctggggatcc gcccccgggc
     1201 tttgccccgg gccccactgg ggatccgccc gggcccccgg taccgcgctt cgcgcggtgg
     1261 cctcaaacgc cggccgggct tggtatgccg cgcagcggca caccagcccc ggcgggcggg
     1321 accggcatgt tccagcctcg ccggcgtttg agacgcgggg ttcggggcgg agccccgacg
     1381 ggaccggcaa gtaccagccc tgccggcgtt tgaggcgcgg ggggccgggg gcggagcctc
     1441 cggttacggg aaggggcggg gtgggggaca ggcccgccgc aggcggtcac cggcccgcga
     1501 cgccgggccc gacacgtacg caatcggcgg cccctgggcc gccccgtcga gaggacgcgc
     1561 atgactacag ccaccacccc gagcgccgcc ggcgccgccg ccgagaacgc cgcgcgggcc
     1621 gggacgttgc gggcggaagg agttcggttc gggtacggcg ggcgggaggt gctcgcgggg
     1681 gtcgatctcg acgtcggcgc gggcgagtgc gtcgcgctcg tcgggctcaa cggctgcggc
     1741 aagagcaccc tgttgcggct ctgcgccggg ctgctgaggc ccgccgcggg ccgggtgagc
     1801 ctcggcgggg acgatctcgc ccggctctcc cgcaggtcca cggcccgccg cgtcgccctg
     1861 ctgcaccagt cggccccggc cgtccccggc atgacggtgc ggcagctggt gcgccagggg
     1921 cgctacgcgg cgcgcggccc gctcggcatg ctgcgggacg gtgacgacgc cgtctgttcg
     1981 cgggccatgg ccgacgtggg cgtcgccccg tgggccgacc gtcctgtcga ctccctctcc
     2041 ggcggcgagc ggcagcgcgt gcggctcgcc atggccctcg cgcaggacac ccgcgtactg
     2101 ctgctcgacg agccgacgac ctatctcgac ctgcgccacc agctcgaggt catgcagacg
     2161 gtggtccggc tccgtgagga gcgcggcctg accgtggtca tggtgctgca cgacctcggg
     2221 cacgcggccc ggttcgccga ccggatcgtg gcgctgcgcg cgggcagggt ggccgccgac
     2281 gggccgcccg ccgaggtggt cacgcctgtt ctgctcgccg aagtccttgg tgtggcaggg
     2341 cgggtggggc tcgatccgga gggcgggtgg ccggtgtgtt acccggatca ccctctgccg
     2401 gtcaccgaac ctcttgcgaa atgaaaatca tattcattag tgttcggtgt gccgccggcc
     2461 ggtccggcgg cacagtccgc aacacccgac gaatggagag ccaactcatg gagcagtaca
     2521 aggtgttcag tccgatcgcc gagcagggcc agctcgccca cctgtccgcc acccactcca
     2581 acgcgctcgt cgagaacccc ttcgacgaca acgccgccgc cgtcgagacc gacagcgaca
     2641 agtaagcccc cgccgggccc gtccggaacg ccgttccgga cgggtccggc ccgcagcgca
     2701 gaccccgaac ccctcaggag aacccgtggc caccgtgcga ctcgcccccg gcgtcgccct
     2761 tgtcaccgtc cccggccacg gcctcgccgt ccggaccccg gacggcgcgt tcctccgcgt
     2821 cgacaccggc gcggcggacc aggacgcgct cgtggcccag ctgacccgtg gctgcggcga
     2881 cgacacggaa ctcgcccgcc tgaccgccgc cttcgccgac gcgggtttcc tggcccggac
     2941 ggacgacatc cgcgcgcccc tcaacggacg caccgtcgtc ctcctcggcg acccggtcct
     3001 caccgagccg ctcgcccgct tcgtccgtgc cgagggcggc gaggtgcgcc atgccgggcc
     3061 cgacgaccta gggggcaccg gtccgtcgac ggccgtggtc tggtgcctgg actcgcccgt
     3121 cccgaacggc ctgtgggacg aggccgaccg actgcctgcc cggggcacct gctggctgcg
     3181 ctgccaccgc gagggcgcca cggtctggac cgagccgttc gctgccgcga caggcgacgt
     3241 cacctccgcg gacgtacggc tccggcggct cgccgcgacc ccggcccacc gcgaactcgc
     3301 cgcctactgg gcgggttcac gcaccgacga cacgggcccc gcccacaacg ccgcctcggc
     3361 cgccctgacg gcctccctga tcaccgccga tctcatcgcc tgggcggcgg gacggcccgg
     3421 gggccgcaga ctgcgccgtg tcgacgtgcg cgacctcacg gtcaccgagc accccgtgct
     3481 gccggtgccg gccgtcgcac cgctcgaccg atgagggccg cgaccgtccc cgtaccgggc
     3541 gcccggctgg caaccgccgt gcaactgccg gacggtgacg gcccgttccc ggccgtcgtg
     3601 atccgtaccc cgtacggaca ggtcggccac cgcgacgagg cccgcgcctg ggcggcccgc
     3661 ggcttcgccg cggtcgtcca ggacgtacgc ggccggcacg ggtccaccgg tgactggcac
     3721 ccctaccggc acgaggaggc cgacagcgcc gcgacgctcc gctgggtccg cggccaccgc
     3781 tggtccgacg ggcgcgtcgt cgccgccggg gcgtcgtacg ccgcgcactg cgcactcgcg
     3841 gccacggcgg ccgtcgagtc ggcggaccgg cccgacgcgg tgatcgccgc ggtgcccgcc
     3901 ctcggcctcg ccgaaacggc ccgcgaggcc ggcggcgtcg aacggctcgc ggcccgcgcg
     3961 ggctggtggg ccgcgcacgg cgaccggccc gactccgacg ccaccgccct cgacaaggcc
     4021 ctcgcccgcg acccccggct cctcgaacat ctccccctga ccaccttccc cgagcgcctc
     4081 ggccgcgccc tgccgtcctg gccggcgctc tgggacgcgt cccgccggcc ccgtccaagg
     4141 ccccgtgcgc ccctcccgct cctcgcggtc ggcggcactc gcgacccgtt cgccgacgac
     4201 accctgcggc tctgggcgga gtgggcgggc cccgcccggc tgctgctcgg cccgtggggg
     4261 cacggcctga cctccgaacc ggcccccgag gcccgcccgg gacaccggat ccggctcggc
     4321 gagctgtacg tgacctgggc acgggccgcc ctcaccggcg ctcttggccg cgaacgccgc
     4381 ggtgcggtcg cgctcggcga cagcgagcac tggtacccgg ccgcgccgga cacgggagag
     4441 cggaccacct ggccgttcgg cgtaccgagc ggcctgcggc tcctgcgggg cggcacgttc
     4501 gtcgccgatc cccaaagccc cgtacggtcc gacgacttga acgtgccgac cggtgaggcg
     4561 cccgaccgcg ccctgctcgt cacgccgccc ctgccccggc ccctcgacct gctcgggacg
     4621 gcggaggccc ggctgtgcgc caccgcggac acccccaccg ccgactgggc ggtacgcgtc
     4681 gtcgccctcg atccggccgg ccgcgcggcg ccgctcgcca ccggcgtcgt ccgcaggtcc
     4741 ggcccgcccg gcgcaccggc cgcgttccgc gtgccgctcg gcccggtcgc gcgccggctg
     4801 cccgccggga cccggctgcg ggtggaggtg gccgggcacc acttcccggc ccacgcccgc
     4861 aatccgcaca ccggtgagga cccggtccgc gccacccgcc tcatcgcctc ccggcggacc
     4921 gtacgcacgg ccggcagcgg ccttctgctg cccgtcgtac gcggcagccg gcccgtcgat
     4981 cccgtacagg agacccgcag ttgaccacta ccctcaccct cgacagcctg gtggaccccg
     5041 tctgcgggct gatacgcggc gtcgagcccg tgccgcaccc ggcgggtgcg ccgccccgct
     5101 acaccgccat gaccgcggac gtcggtgacg cacgccgctt cggggcgtgg ccggccgacc
     5161 gggtgtccct cggcacgacc ttcggcgatc cggagggcgc gcggatcgcc gccgtcgccg
     5221 aggccgtcga acgctactgc ggcaaccggc tgcccccgcc gggacacccc ggcgcaccgc
     5281 gcagggcaac cgccgccgaa ctcgtggcgg agggcggcac cgtgtacggg ccgggcgagc
     5341 tgcccgccta cgccgactgg cagtacgcac gtcccgggtt cgagtaccgc cgtctcaccg
     5401 cggacactcc ggcgctgtgg gcccgcgggc aggagaacgg cgaggagtgc tgggcgcccg
     5461 tcgcgctcac ccacctcaac tggcgtcagg gcgacctgcg gtccctgccc cgtacgcacc
     5521 atctcaacta cgccgggatc gccaccggcc agggcttcga cgacgccgtg gagcgagggc
     5581 tgctggaagt cgtcgaacgc gacgcgctcg aactgtggtg gcatctcgac ggccccgccc
     5641 gcggcataga ccccgcctcc gtccccggtc tcacccgcga cctcgacggc tgtgacctcg
     5701 aggtctccat cgtggagatg ccctccgagt tcgcgccgtg catggcggcc ctcgtgcacg
     5761 acccggcacg cggcatccac gccgccggtt tcgcctgccg ttacgacccg gcggaggccg
     5821 cccgcaaggc cgtcctggag gcggtgcaca cctgggtctt cacccagggc gccaccgacg
     5881 ccgacggctg ggtcttccgc gcgatcgacg ccgggatgct ggcacgcggc ctctacctcg
     5941 accaccgggc cgaccgccgc tacctcgacg actgcggcac cgacttccgt gccgtacgcg
     6001 acctgggcgc gcacgtccag gtatggctcg acccgcggat ggcgccgctg gccggccgct
     6061 tcacccgtcc ggcgctcggc gtggtcccgg tcgacgaggt ggcggcgggc agcagggccg
     6121 tgctcgacga acgcctggcg gcgggcgggc accgggtcat caccctcgat ctgaccacgg
     6181 aggacgtcgc ggagacgccg ctgcgggtgg cgcgtgtgct cgtctccggg ctcgtcccca
     6241 acgcgccggc cgcgttcgcc tacctcggct gcccgcgctt cgggcacgcg gcgcgggcac
     6301 gcggctggcg caccgaagtc ccgcagtccg cgagcgactt cacgctcgca ccgcccccgc
     6361 acatgtgagg caccgatgga gtcgtccgtc acccgagcgc tgaccctggc ccgttccgcg
     6421 caggcccccg gcccggactt cccggccggt ccggcgagcg tgcccctgcc gggggaggcg
     6481 ctgcccgtcc cggcccggct cgaccggatg ctgcggctgt ccctcgcggg ccgcaggctg
     6541 cggcccgtcc cgtcggccgg cgcactccac cccgtcgaca cgtacctgct cgtcggggcg
     6601 ggctgcgggc tgccgccggg cgtccacgtc tacgacccgg cgcgccaccg cctgcaccgg
     6661 tgcggccccg ccccgtgccc ggcgccgccg ggtgccgtcg ccgtcctggg cgtcaccgcc
     6721 cgccgcaccg tgtcgcacta cggccaccgt gcctggcccc tggtgctcct ggacgtgggc
     6781 cacgcggcgg ccgcgctcgc cctggccggg gcgcacgcgg tgtgcctgga cgccgacggc
     6841 gggctgctgt cgggcgcgag cggcgcaccg gtggccctgg ccgccgtccg gctgacggcc
     6901 gacgcggcgc cggacggcct cgtccgctgg gcggcccgtg cgaccggagg gcggatcccg
     6961 gccccggagg ggcccgaggt cctgcgcacg gccgtggcgg tcctcgccga actcgccgcc
     7021 gccggcggga agtccggcac ctggcgcgct gccacgggcc ccctcctgcc ggactccgtg
     7081 ctgctgtcgc ggcgcagcgc gccccccggg ttccacgacc tgccgcccca cgaggcgctg
     7141 gcgcgtgtcc tggcggcggc gcgggccgcc tccccggacg gcctcggctg gaccctcgcg
     7201 gtgagcggcc cccgccccgg cctcctgacg gcccccacac ccgcgccgcc tgccgagtcc
     7261 accgtgcccg gttccgccgc cgcgccggcg caccgcaccg ccccggccga cggctccctg
     7321 ccaccgctgc gccgcctcgg gtcgagtccg gccgatccgt tcgggaccgc gccggccgcc
     7381 gggaccgtgc caccgctgcg ccgcctcgcg tcgggcgacg tgctgccgac cctcgcccac
     7441 tgggccgccg gacagggctg gatcgccgga gccggagccg tgctcctcgc ccacggctgc
     7501 ccctccggcg ccacggcggc ccaggtgcgg cactgccacc tcgccgccgg acacggcgtc
     7561 gcccacgccc aggctgcggc gaccgccctc ggcatccact cccggcccgt cggctcctgg
     7621 cagggcgccg acctcggggc cgcgctcggc ggaccggccg ggcgcgactg ggtcgtgcac
     7681 ggcctggccc tgggccgtac gacacaagga gacgaaccgt catgatgctc cacccggagc
     7741 tgctgcgcgc cgcgcgcacc gcgcgccgcc ccctgctcac ggccaccgcg ctcctcgcgg
     7801 ccgtcgcggc gacccacctc gcccaggccg tgctgctcgc cctcgtcctg gcccggatcg
     7861 cccgcggcga caccggcgga gcgccgttgc cgctgctgct cggcgcggtc ctcacggccg
     7921 tgctcgtacg cgccgtcctc ggccgcctcc agcggcgtgt cgcggtgagc gccggagccg
     7981 ccgtgcggac cggtctgcgc gaccggctgc tcgaacgcct cggccgcacg ggccccccgc
     8041 agcacgcgga ggcccgcgcc ggcgccgtac gcgccaccct cgtcgacggt gtcgaggggg
     8101 tcgacgcgta catctcccgc tatctgccgc agctgctgat cacctgcgcc gtgccgccac
     8161 tgctgctgat cgcggtggcg gccgtcgaac cgtggaccgt cctcgccctc ggacccgccc
     8221 tcgtcgtcgc gctgttcgcg ccgcgctggt gggacaagct gctggaacgc cggggacagc
     8281 agcactgggg cgcctacgag gccctgtccg cggactacct cgaggcgctg cagggcatgc
     8341 ccgccctgcg cgccgccggt gcggtgggcc gtaccagggc gcgcctggag gagcggtcgc
     8401 gggcgctgca ccgggcgacg gtcgccaaac tccgcgtctc gctcgtcgac accgggatca
     8461 ccgacctcgc cgtgcagggc ggcacggtcg ccgccgcact cgtcgcctgc gcgtccgccg
     8521 cgtcggggca cgcgacgccc acggccacct acctggtcct gatgctcgcc tccgaatgct
     8581 tccggccggt acgggacctg tccagggagt ggcactcggg atacctcggg gtgtcggccg
     8641 cggacgggat cgccgagctg cgcaccgcgg aggggggcgt ccccgacacc gggcggaccg
     8701 tcgccgcctg gcacgcggct cccgaagtcc gcttcgagga cgtgcacttc acgcatcccg
     8761 gcggtcgcgg tcccgccctg ggcggcgtga gcttcaccgc acgccccggc cgggtgacgg
     8821 cggtcgtcgg cccgtccggg gccggcaagt ccacactgct cggcctgctg ctgcggcgcg
     8881 cggacccgga cgagggccgg gtactcgtca acggcgtcga caccaccgcg tacacgctcc
     8941 cgtccctgcg gcgggggatc gcggtcgtct cgcaggagac gtacctcttc cacgcgaccg
     9001 tcgccgagaa cctgcgcctg ggcgcccccg gcgcgagtga cacggcgctg cacgacgcgg
     9061 cccgcaccgc cggcatccac gacgagatcg tcgggctgcc cgacggctac gacaccctgg
     9121 tcggcgagcg cggtgcgacg ctctccggcg gacagcgcca acggctggcc ctggcgcggg
     9181 cgttgctcgc cgacgcgccg gtcctcgtgc tcgacgaggc gaccagcgcg gtcgacgagc
     9241 atcgcgaggc ccgcatcgtc gaagagctgc tgcgggccgc ccggggccgt acatgcctgg
     9301 tcgtcgcgca ccggctcgac tccgtacgcg aggccgacac catcgtcgtc ctcgacggcg
     9361 gacgggtgga cgccgtcggc ggccacgccg gcctgctcgc gggcgacggc gtgtacgcgc
     9421 gcctcgtcgc ggccggacac accgacacgg aaagggccgc atgaaccccg aacgaggcgc
     9481 cctgcgcgcc ctgctgcccg tgctcgcggc gcaccgcgcc atgaccctgc gcaccttctg
     9541 cgccgcgctc gccggccagg cgtcgctcgt cgcactggtc accctcaccg cccacaccgt
     9601 cggcacggcc gtcgtcgagc ggcgggcccc gggcgccggc acggtcgccg ccctcctcgc
     9661 gctcgtcgcg gtccgtgccc tcgcgacctg gcgggagatg gacctctcgc acgacctcgc
     9721 ctaccgggtc ctcgcggaac tgcgcatccg cgtcttcgac ggcctcgccc gcagcgcgcc
     9781 cgcgcgcatc gcgggacggc gcagcgggga cctggcgtcg gcggcgctcg gggacgtgga
     9841 ggcgctggag ttcttctacg cccacgccgt ggcgcagctc gccgcctccg gcgtggtgtt
     9901 cgggggcgga acggtcgccc tcgggctgct tgacccctgg ctgctgctcg ccgtgctgcc
     9961 cgtcgcggcc ctgctcacgc tcgccccggt gctggagtca cgcggccggg cggcccgcgg
    10021 agcccgcacc cgtgcggcgg ccgccgacct gtcggcggag accgtcgaga cggtcgacgg
    10081 actgcgggaa ctgctgacgt tcggcgcgct cgacgcccgg cgcgaacggc tccgtgccca
    10141 cggcaggcgg ctcggcgacg cccagcgtgc cgagcaggca tgggaggccg acgcctcggc
    10201 cgtgcgtgac ctcctcgtcg tcgtggccgt cctcggagtc gtcctcgccg cggcgcacac
    10261 gttcgccggc gcgtgggctc ccgccgcgat ggcgctcgcc ctcggcgtgc tcgcgcccgt
    10321 cgcagactcg gccgccgcac tcggccaggc gggcgggctg cgggcggcgg cggcgcgggt
    10381 gggcgcggcc gtacgggccc cggcgggtgc ccccgagccc gccgcgcccc ggggcctgcc
    10441 cacgggaccg ctcggtctgc ggctgcggga cgtccgcttc gactacggcg gccgcgccgt
    10501 gctcgacggg gtggacctga cggtccggcc cggcgagacg ctcgccctcg tcggcgtctc
    10561 cggcgcgggc aaatcgacgt gcgcgcacct ggtggcccgg ttctgggacc cggcgtcggg
    10621 cacggtcgaa ctcgtcccgg aaaccggccc gccggtcgac ctgcgcgact tggccgaggc
    10681 cgacctgcgg gccgcggtgg ccgtcgtcgg ccaggacgcg ccgctgttcc acggcaccct
    10741 ggccgacaac ctccgcctcg cctcgccgac ggcgacagcg acggacgacg aactggccgc
    10801 cgtcgcccgc cgcacgggcg tcgaccgcat cgccgacggc tacgacaccc tggtcggcga
    10861 gcgcggcacc accctctcgg gcggccagcg cgcccgcatc gccctggccc gcgcgctgct
    10921 gacccgcccg cgggtcctcg tcctggacga gacgacggcg aacctcgaca ccgagggcga
    10981 cgccgcggtc tccgcggcgc tcagggacgg ctccccgtcc cgtacgaccc tgctgatcgc
    11041 ccaccgcccg tcgacgatcc gccgcgcgga ccggatcgcg gtgctggagt cggggcgggt
    11101 ggtgcagacg ggcacgtggg atcaactgac ggagcaaggg ggcgcgttcg cccgcgtcct
    11161 gacgcgctga gtgggcgggg cggatccgct gcacggagct gtcccctccc cgccccttcc
    11221 caaaaccggg ggctccgccc ccggaccccc gaacggggct ctgccccgcg cccgtaccgg
    11281 ggcaggcccg gggccccggg cggggctctg ccctcggccc cgtggggcct acgccccgag
    11341 cgccggtaga gggctgcccc cgggcccc
//
