LOCUS       NZ_CP107567            21080 bp    DNA     linear   CON 18-NOV-2023
DEFINITION  Streptomyces peucetius strain NA0869 chromosome, complete genome.
ACCESSION   NZ_CP107567
VERSION     NZ_CP107567.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces peucetius
  ORGANISM  Streptomyces peucetius
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8050611)
  AUTHORS   Zhao,E. and Ge,H.
  TITLE     Cytochrome P450 Catalyzes Benzene Ring Formation in the Biosynthesis
            of Trialkyl-Substituted Aromatic Polyketides
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8050611)
  AUTHORS   Zhao,E. and Ge,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2022) School of Life Sciences, Nanjing University,
            No. 163 of Xianlin Avenue, Qixia District, Nanjing, Jiangsu 210033,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: unicycler(0.4.8) v. v. 3
            Assembly Name                     :: NJU_NA0869
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/18/2023 06:49:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,216
            CDSs (total)                      :: 7,126
            Genes (coding)                    :: 6,825
            CDSs (with protein)               :: 6,825
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 303
            CDSs (without protein)            :: 301
            Pseudo Genes (ambiguous residues) :: 0 of 303
            Pseudo Genes (frameshifted)       :: 144 of 303
            Pseudo Genes (incomplete)         :: 227 of 303
            Pseudo Genes (internal stop)      :: 22 of 303
            Pseudo Genes (multiple problems)  :: 85 of 303
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:23:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6368740
            Orig. end                         :: 6389820
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP107567.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from IFB-NA0869, Nanjing
            University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21080
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="21"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21080
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21080
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11080](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11080)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    124..136
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            124..522
                     /locus_tag="OGH68_RS28910"
                     /old_locus_tag="OGH68_28910"
     CDS             124..522
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133893.1"
                     /locus_tag="OGH68_RS28910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28910"
                     /product="RidA family protein"
                     /protein_id="WP_264247962.1"
                     /transl_table=11
                     /translation="MTLSRHNPAELSPPAGFSHAVTATGSRLVFLAGQTALDTDGKVVG
                     GTLPEQFETALTNLLTALASAGGTPHDLARVTVYATDVADYRAHAAELGRIWRRSAGRD
                     YPAMAVIGVVRLWDEQCLVEVDGVAVMP"
     gene            722..2200
                     /locus_tag="OGH68_RS28915"
                     /old_locus_tag="OGH68_28915"
     CDS             722..2200
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003093.1"
                     /locus_tag="OGH68_RS28915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28915"
                     /product="MFS transporter"
                     /protein_id="WP_264250337.1"
                     /transl_table=11
                     /translation="MALFVIASCQLMVVLDITIVNIALPHIQRSLEFSTTSLSWVVNAY
                     TLTFGGLLLLGGRAGDILGRRRVFMFGVLLFVLASLLGGLAQSSGQLLAARALQGVGGA
                     IASPTSLALITTTFTEGPARNRAFGVFAAVSAGGGAIGLLAGGMLVEWLDWRWVLFVNV
                     PIGLLIAFAAPRWIRESGRHPGHFDLSGALLSTLGMVSLVYGFIRAAQHGWRDAYTLAS
                     FSAALVLLTAFLMVERRSKQPITPLHMFADRNRAGTYGMMLGLAAAMFGMFFFLTLFVQ
                     NVLGFGPLRAGLAFLPVSAVIAVGAGLASQLLPKYGPKPFMVTGAALAAAGLAWLTLTD
                     IHSTYAGSILGPMLVFSLGMGMQFVSLTLMALSGVPTHESGAASGLLNATQQVGGSLGL
                     SILVTVFGTVSGNEAKDQIPRFMAEATPAERLAFRRTGELPPPWGDQVLTSGVSAAFVM
                     AAVFAVLAALIAVLAIQVRPADLERLKGGVGPGA"
     gene            complement(2296..2757)
                     /locus_tag="OGH68_RS28920"
                     /old_locus_tag="OGH68_28920"
     CDS             complement(2296..2757)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010468138.1"
                     /locus_tag="OGH68_RS28920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28920"
                     /product="SPW repeat protein"
                     /protein_id="WP_264247963.1"
                     /transl_table=11
                     /translation="MTTHADIEQHPDLAEMRSRFERATSTPRAQAVETLALITGLYLAA
                     SPWIAGFSGLTNLAVANLITGIAFALCMGGFSSAYERTHAMAWTACAIGAWTIISPWVV
                     AGAMDTTRSVVNNVIVGAVALLCGLAMAATAGTRGARGRRRGPGPSPAD"
     misc_feature    complement(2933..2948)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            2966..3799
                     /locus_tag="OGH68_RS28925"
                     /old_locus_tag="OGH68_28925"
     CDS             2966..3799
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892379.1"
                     /locus_tag="OGH68_RS28925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28925"
                     /product="Gmad2 immunoglobulin-like domain-containing
                     protein"
                     /protein_id="WP_264247965.1"
                     /transl_table=11
                     /translation="MNIWLTSRLVAVAATTALVLTGCTGSGGSTNASASPSGGPRASAQ
                     PSGGPKSDAPTTPSTGATPTASASGRGEPMPGFPGLQPLWPFSTLGQAEKWESQFRAGG
                     HQPWHLDAEQTALSFTRNYLGFEGLDRVTSRAVDGREARIGVGLSGTESTGTAAVVHLV
                     RYGTGPDAPWEVVGTDDTTFTLTAPAYGSVVRSPVTVGGRMTGVDESVRVEVRQPSAER
                     PLGTSCCTSAGGKEQPWQSSVSFTGAVDPVLTIVASTGGHVAEVERFAVTAVRSG"
     gene            3864..4052
                     /locus_tag="OGH68_RS28930"
                     /old_locus_tag="OGH68_28930"
     CDS             3864..4052
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OGH68_RS28930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="OGH68_28930"
                     /product="hypothetical protein"
                     /protein_id="WP_264247967.1"
                     /transl_table=11
                     /translation="MSQANAPDGGSVVHVDVHERQARAVLTGDTLFLSRFPDGWKVMAA
                     GCTPQQDRPYQCEIKGG"
     gene            4139..4855
                     /locus_tag="OGH68_RS28935"
                     /old_locus_tag="OGH68_28935"
     CDS             4139..4855
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010038376.1"
                     /locus_tag="OGH68_RS28935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28935"
                     /product="DUF6766 family protein"
                     /protein_id="WP_264247968.1"
                     /transl_table=11
                     /translation="MSSRTATASGRTGRLGRFLRDNGLGLAFITAFLVVLVAQAFAGHA
                     AYNNRLLTDGMARAGLGDYITSSDFGVDVMENWQSEYLQFFLYIFATVWLVQRGSPESK
                     ELHKAGRESDEDQMVGERARDDSPGWAASRGWRQGAYARSLGMVMGLIFLLSWLAQSIT
                     GTAAHNERRLRRLQAPTSWSEYVFSADFWSRTLQNWQSELLAIGSMAILSIYLRQRGSP
                     EFKPVGSGHAETGVEG"
     misc_feature    complement(5750..5766)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.62"
                     /tool="antismash"
     gene            5783..7189
                     /locus_tag="OGH68_RS28940"
                     /old_locus_tag="OGH68_28940"
     CDS             5783..7189
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018558480.1"
                     /locus_tag="OGH68_RS28940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28940"
                     /product="ATP-binding protein"
                     /protein_id="WP_264247970.1"
                     /transl_table=11
                     /translation="MALIFVPAQTRTTVAWCGLAAVVLTVLTSAGTARRTRAVDAARYE
                     QASTEAQAYFAQREAALIGRLSDQRATTVWLAEELLPAAVARLQKGDPASEIMQSVRFG
                     EHLDSEFREALRAALRTLLEAVEAEEHTRDSSQRALVAIARRVQAIVHQLAKDLRSMQI
                     LHGTDVVVSHGLQDIDHRNALIGRLAASIAVLGDARPGRQWSKAIPLYDVLRGAMSRIV
                     DYPRVKLQSVTEVAVIGPGAEPLIHLLAELLDNATTFSPPDTPVDVTASEVPSGIAIEI
                     EDRGVGLTEEVRQRVDRVMAQSSSGIQLAGLGEVTQLGLAVVSRLAREHGLDVDLRTSA
                     YGGVRAVVLVPRSLITTVQQPAANAALPPARKHTDGPIVPRQTPPGPDASDAVEVRATV
                     NGLPQRRRESPVPKPVVRTTPHPPAAPAASPGNNGMPRQPGLMWEAFNGDKRSSAEPST
                     ENSESSDEGE"
     gene            7191..7598
                     /locus_tag="OGH68_RS28945"
                     /old_locus_tag="OGH68_28945"
     CDS             7191..7598
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031762.1"
                     /locus_tag="OGH68_RS28945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28945"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_264247971.1"
                     /transl_table=11
                     /translation="MQPLPNIDWMLKELTASVPYVRHVVVLSSDGLCIGQADTEPDTAD
                     GIAAACSGIQSLAKAIAQKFPHGDGSTRMVGIEVDGGYFSLMAAGPGAYLAVLADEEVD
                     AGLLGDRMRTLVVRIGQHMTSPPRDDVGRAM"
     misc_feature    7210..7225
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.82"
                     /tool="antismash"
     gene            7595..7951
                     /locus_tag="OGH68_RS28950"
                     /old_locus_tag="OGH68_28950"
     CDS             7595..7951
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031761.1"
                     /locus_tag="OGH68_RS28950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28950"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_264247973.1"
                     /transl_table=11
                     /translation="MTSENQDTWDEGSPVPLFVITGGPGSSAEAFNLVTLIAARSTPEP
                     GMQPEQAAIVSMCRYPLSVAEISAYLSLPFSVVTVLLSKLVDDGRVEATAPVPVASYPE
                     LGLLEAVIHGLRKL"
     gene            7932..8555
                     /locus_tag="OGH68_RS28955"
                     /old_locus_tag="OGH68_28955"
     CDS             7932..8555
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944873.1"
                     /locus_tag="OGH68_RS28955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28955"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_264247974.1"
                     /transl_table=11
                     /translation="MDYVSSDAPTAGPRGTDVLLPHGARGVKVVIVGGFGVGKTTMVGS
                     VSEIPPLTTEETMTQAGVGIDHNPGAEGKSTTTVAMDFGRISINRELILYLFGTPGQER
                     FWFLWNGIFEGAFGAVVLVDTRRIDVCFEVITRLEDRRVPFIVAVNTFPEAPQHPISAL
                     RTALALNESVPIVTCDARDRSSCRDALLSLMVYLRTLAAAQESA"
     gene            8552..9997
                     /locus_tag="OGH68_RS28960"
                     /old_locus_tag="OGH68_28960"
     CDS             8552..9997
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031759.1"
                     /locus_tag="OGH68_RS28960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28960"
                     /product="cytochrome P450"
                     /protein_id="WP_264247977.1"
                     /transl_table=11
                     /translation="MTVPPAEHTTPQGGPTPPPGCPAHTTAGAGGVTRLHGAAAETDPM
                     GLYEKLRAAHGPVAPVLLDGDVRAWLVLGYLENRDVASRSTQFSRDPRTWHGWTSGEID
                     PTTSPLMPMIGWRPDCVCADGEEHQRLRGAVTAGLDQFDQRGIRRHITRFAHQLIDGFC
                     ESGEVELVGQFTEHLPMLVLTHLLGMPDESGPKLVHAARDLFKGTETSLASNAYVLETL
                     EQLVVTKRTRPGQDIASVLMSHPAGLTDEEVQHHLRLILLAGYETTANLMSNVLRMVVT
                     DPRFRGSLAGGQMTLPEAVEQVLWDEPPLMVCPGRWAKGDTSLGGQQIKAGDMLLLGLA
                     AGNVDQAVRPDLSTPVHHNRAHLSFSAGTHECPGQDIGRVIADTGIDILLTRLPDIALA
                     VPESELTWRSSTWARHLTALPVSFAPRAPRAHDVPASLPAPPSPTGGLPAVPPRPVAGP
                     LPERAPEPRGSWWVRLRRLLRRR"
     gene            complement(10001..11080)
                     /locus_tag="OGH68_RS28965"
                     /old_locus_tag="OGH68_28965"
     CDS             complement(10001..11080)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.2"
                     /locus_tag="OGH68_RS28965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28965"
                     /product="terpene synthase family protein"
                     /protein_id="WP_264247978.1"
                     /sec_met_domain="T1TS (E-value: 5.7e-59, bitscore: 199.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVQAVKLPGLWMPHPARVNPYLPALREETETWAREMGMLGGDER
                     PTARRAIWSRSQFHAMTVDQLTASTLPDASLAALRLNHRFNIWALAWDDYFASAFKRTG
                     DLAGALVFTSRLHAFLRPEPGARLPEPTNAVERGIADLQPHLFPPRLAHWRHGFNQALA
                     RYIDAGVQELANSRAGRVPDLIEYAQFRRESFAAYTAPYSVELATGARIPEQIRHSRTV
                     RALLDAFMDYMGLANDIASYRREVHEERDVNNLVLVLATSMGITIQEAVRAAVDLVNAR
                     LRHFEHLRHSELPLLVERAGLHAGEQAELETWLRGACGFLSGLHSWYTGAPRYVPADIP
                     FPEQRTSTSAVMRTCDANP"
     misc_feature    complement(10697..10699)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11622..12305)
                     /locus_tag="OGH68_RS28970"
                     /old_locus_tag="OGH68_28970"
     CDS             complement(11622..12305)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740747.1"
                     /locus_tag="OGH68_RS28970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28970"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_264247979.1"
                     /transl_table=11
                     /translation="MDSFEEPVASGAGGAGPQVPLTSERARTEITDKRLLRGARTRQTV
                     LRQAVDIASLEGLSGVSFGRLASGTGLSKAGIQTLFKTKETLQLAVVDFAREMFIDAVV
                     RPASSARRGTARLRALLDHWIVYAETPLFAGGCFRAANLAEFDSRPGPVRDSLFRDQEE
                     WRGVIATELGHAVDSGEITDLDVELTAFQIDALLCAANTALRTGDSDAVNKVRRIVDGL
                     LAPPA"
     gene            complement(12374..13051)
                     /locus_tag="OGH68_RS28975"
                     /old_locus_tag="OGH68_28975"
     CDS             complement(12374..13051)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740746.1"
                     /locus_tag="OGH68_RS28975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28975"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_264247981.1"
                     /transl_table=11
                     /translation="MTATQLTEESDPFCLPPLDAAALLFDTPWSRFAVIGDSLSAGTGD
                     ASPGYTDAGWSDRIADILRRVRPDLEYLNTAEIGATTSRTLEKQIDRLLEFAPDLLHLP
                     CGANDLARRRPDFDEIGRTLRRMYEMASRTGAQLTTFTLGRAYVVPVFSDWSERVTRVN
                     DITRALADEYGAVVVDMWDHPVNDRHGLLSADRIHFSTSGQAVMATEMVKGLAGVLSRT
                     PRA"
     misc_feature    complement(13084..13097)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.55"
                     /tool="antismash"
     gene            complement(13276..13878)
                     /locus_tag="OGH68_RS28980"
                     /old_locus_tag="OGH68_28980"
     CDS             complement(13276..13878)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379461.1"
                     /locus_tag="OGH68_RS28980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28980"
                     /product="response regulator transcription factor"
                     /protein_id="WP_264247982.1"
                     /transl_table=11
                     /translation="MITVLVVEDHAVVRSGLTALLSGELGMAVVGQAADGPAALAEAER
                     LRPDVVLLDIDLPVTDGITVAATLAERLPGCRTLILTALDRPGHLRRAMDAGASGYLLK
                     SATPAETADAIRRVAGGGRVIDSRMPDSWVGEVSPMTDREAEVLRLASNGAHAREIAAD
                     LFLSVGTVRNRLSSAVAKLHARTLLDAVRIAERHGWL"
     gene            14020..15153
                     /locus_tag="OGH68_RS28985"
                     /old_locus_tag="OGH68_28985"
     CDS             14020..15153
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018847512.1"
                     /locus_tag="OGH68_RS28985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_28985"
                     /product="histidine kinase"
                     /protein_id="WP_264247983.1"
                     /transl_table=11
                     /translation="MTAPPGARVAFGTLVVLVVGTLGLVALDVAASPLGRRAMVTGLTV
                     LVLMPAVLLGQYVPPPYRLSRRWRWGLLLAQAALTYLPLVVFHYPWLTLLGFLAGAVLL
                     TLPPATSVPVALAVGASGPLLIHTGVIDTDRGSLSVVLSTAITASAVFAVAHLALVSAR
                     LHGAREQTVRLAEQRTRARMRQDLHDLVGSSLVAIVIRGEAALRADVSAASARSVLAEV
                     VALARRTHEDVRLISGPETTLSLAEEFAHAQRLLTSAGIAVRTSLPPHVEPDRAVVNCL
                     RSVLHEAVGNVLEHSRAGFCEIELRAGDDDIRLTVRNDGVAATGSVPAAVRTVGHRGTG
                     LVGLKGRVIALGGTLHVGPTGREFSVAAVLPLGRDGA"
     misc_feature    16606..16620
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.38"
                     /tool="antismash"
     misc_feature    complement(16978..16990)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.45"
                     /tool="antismash"
     misc_feature    18235..18250
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.13"
                     /tool="antismash"
     misc_feature    20353..20373
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.53"
                     /tool="antismash"
     misc_feature    20893..20908
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.92"
                     /tool="antismash"
     misc_feature    complement(20910..20930)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.71"
                     /tool="antismash"
ORIGIN
        1 cctcgaacac ctctaccgcg aggtccgggc gccccggatc tacgagggcg ccaccgaggt
       61 ccagcgcacg atcatcgcga aggagctcta cgccgaggaa caccccgcag aggaaaggtc
      121 ccgatgacgc tgtcccgtca caacccggcc gaactgtccc cgcccgccgg cttctcccac
      181 gccgtcaccg ccaccggctc gcggctggtc ttcctcgcgg gccagaccgc cctcgacacc
      241 gacggcaagg tcgtcggcgg gacgctcccc gagcagttcg agaccgccct gaccaacctc
      301 ctcaccgccc tcgcctcggc cggcggcacc cctcacgacc tggcgcgcgt caccgtctac
      361 gcgaccgacg tcgccgacta ccgcgcccac gccgccgaac tgggccggat ctggcgccgg
      421 tcggccggcc gcgactaccc ggcgatggcg gtcatcgggg tcgtacggct ctgggacgag
      481 cagtgcctcg tcgaggtgga cggggtggcg gtcatgccct gaggcggccc gccccccggc
      541 ttgatcgact ggtgacgctt cacccggaag gcttaacgtc gaacggtgga cggcctcgtc
      601 caccgcctcg tcgagggtcc cgcacggggc gtcccttccc gaggcacgat gcgccatgac
      661 gtctccgcag ccgtctcccg cagtgcacac ctccgccccc ggcaggggcg gcgggaacgg
      721 aatggccctc ttcgtcatcg cctcgtgcca gctgatggtg gtcctcgaca tcaccatcgt
      781 gaacatcgcg ctgccgcaca tccagcgctc gctggagttc tccaccacca gcctgtcctg
      841 ggtggtcaac gcctacacgc tcacgttcgg cggcctgctg ctgctcggcg ggagggccgg
      901 cgacatcctc ggcaggcggc gtgtcttcat gttcggcgtg ctgctcttcg tgctggcgtc
      961 cctgctcggc gggctcgccc agagctccgg ccagctgctg gccgcgcggg ccctgcaggg
     1021 ggtcggcggc gcgatcgcct cgccgacctc cctggcgctg atcaccacca cgttcaccga
     1081 gggccccgca cgcaaccgtg ccttcggtgt cttcgctgct gtctccgcgg gaggtggcgc
     1141 gatcgggctg ctggccggcg gcatgctcgt cgaatggctc gactggcgct gggtgctgtt
     1201 cgtcaacgtg ccgatcggcc tgctcatcgc cttcgccgca ccccgctgga tcagggagtc
     1261 ggggcgccac cccggccact tcgacctctc cggcgcgctg ctctccaccc tcggcatggt
     1321 ctcgctcgtc tacgggttca tccgcgccgc ccagcacggc tggcgcgacg cgtacaccct
     1381 ggcctcgttc agtgcggcgc tggtgctgct cacggccttc ctcatggtgg agcggcgctc
     1441 gaagcagccg atcacgccgc tgcacatgtt cgccgaccgc aaccgtgcgg gcacctacgg
     1501 catgatgctg gggctcgccg ccgccatgtt cggcatgttc ttcttcctta ccctcttcgt
     1561 ccagaacgtg ctgggcttcg gccctctgcg ggcggggctg gccttcctcc cggtgagcgc
     1621 ggtcatcgcc gtcggcgccg gcctggcgtc ccagctgctg ccgaagtacg gcccgaagcc
     1681 gttcatggtg acgggtgccg ccctggccgc cgccgggctg gcgtggctca ccctcaccga
     1741 catccactcc acctacgccg gcagcatcct cggcccgatg ctggtcttca gtctcggaat
     1801 gggcatgcag ttcgtgtccc tgacgctgat ggcgctgtcc ggggtgccga cgcacgagtc
     1861 gggcgcggcc tccggactgc tgaacgccac ccagcaggtc ggcggttccc tgggattgtc
     1921 gatactggtc acggtcttcg gcaccgtcag cggcaacgag gcgaaggacc agatcccccg
     1981 cttcatggcg gaggccactc cggcggagcg gctcgcgttc cggcgcaccg gtgaactgcc
     2041 gccgccctgg ggcgaccagg tgctcacgtc cggtgtctcg gccgccttcg tcatggccgc
     2101 ggtcttcgcc gtgctggccg ccctgatcgc ggtgctggcc atccaggtcc gtccggccga
     2161 cctggagcga ctcaagggcg gtgtcggtcc cggtgcctga ccaccgcgac gccggctcgg
     2221 acctgggaac gtggcgcggg cagggagaag gccccggcgc tccctcgccg gggccttcgt
     2281 gacgagcggt gacggtcagt cggcggggct cggtccgggg ccacgacgac ggcctcgggc
     2341 gccccgtgtg cctgccgtgg cggccatggc caggccgcag agcaacgcga ccgcaccgac
     2401 gatgacgttg ttgacgacgc tgcgtgtcgt gtccatcgca ccggcgacga cccaggggga
     2461 gatgatcgtc cacgcgccga tcgcgcatgc cgtccatgcc atggcatggg tgcgctcgta
     2521 tgccgagctg aagccgccca tgcacagggc gaaggcgatt ccggtgatca gattggccac
     2581 ggccaggttg gtcagcccgc tgaagccggc gatccatggc gaggccgcca ggtagaggcc
     2641 cgtgatgaga gccagtgtct caacggcctg ggcgcgcggc gtgctggtgg cccgctcgaa
     2701 gcgggaacgc atctcggcca ggtccgggtg ttgctcgatg tctgcgtgag tggtcatgat
     2761 gggccgcctc ctgcttgcag ccttatgtgt cctttatgcc atggaacgcc cttttgggtg
     2821 gtctggtcaa atgggtaatt tccctttccg cggccgtgtg tcggcggcgg accggacgcg
     2881 gccttgcggc ggggtcgggt ggcggggtgg cacgatggcc tgtacggccg gatgtgacgg
     2941 ccgtcacctg ctccctgggg gaccgatgaa catctggctc acgtcccggc tcgtcgccgt
     3001 ggccgccacg accgctctcg tactcaccgg ctgcaccggc tccggcggct ccacgaacgc
     3061 gtccgcgtca ccgtccggcg gaccgagggc gtccgcgcag ccgtcgggcg gccccaagtc
     3121 cgacgcaccc accaccccgt ccaccggcgc gacgccgacc gcgtccgcgt caggccgcgg
     3181 cgagccgatg ccgggcttcc ccggcctcca gccgctgtgg ccgttctcca cgctcggcca
     3241 ggccgagaag tgggagagcc agttccgcgc cggcggccat cagccctggc atctcgacgc
     3301 ggaacagacc gctctgtcgt tcacccggaa ctacctgggc ttcgagggcc tcgaccgggt
     3361 cacctcacgg gccgtcgacg gacgtgaggc gcgtatcggc gtcggactga gcgggaccga
     3421 gtccaccggc accgcggcgg tcgtccacct cgtgcgctac ggcaccggac cggacgcccc
     3481 ctgggaggtg gtgggcaccg acgacacgac gttcaccctg accgcgcccg cctacggatc
     3541 ggtcgtacgc tccccggtca cggtcggcgg gcggatgacc ggtgtcgacg agagcgtccg
     3601 cgtggaggtg cggcagccgt cggcggagag gccgttgggc acctcatgct gcacttcggc
     3661 gggcggcaag gaacagccct ggcagtcgtc cgtctcgttc accggcgccg tcgaccccgt
     3721 gctgacgatc gtcgcgtcca ccggcggcca cgtggccgag gtcgaacggt tcgcggtcac
     3781 ggcggtacgc agcggctgac cgcctcgcgg acgtcacccg ccaggaggtc gaacagtcca
     3841 cgtgcggccc gtgcgagaag ggcatgagcc aggcgaacgc ccctgacgga ggcagtgtcg
     3901 tccatgtcga cgtccacgag cggcaggcgc gcgccgtcct gacgggcgac accctgttcc
     3961 tctcgcgttt cccggacggc tggaaggtca tggcggcggg ctgcacaccg cagcaggacc
     4021 ggccctacca gtgcgagatc aaaggtgggt gacgggtcgt gaaaggtctg ttcatcatga
     4081 cactgctcgt catcctcttc ggcatcgcgt acttctcggc actggggctg atgcagcgat
     4141 gagctcccgt accgccacgg catcaggaag gaccggcagg ctcgggcgct tcctgcgcga
     4201 caacgggctg ggactggcct tcatcaccgc cttcctggtc gtgctcgtcg cccaggcctt
     4261 cgccggacac gccgcgtaca acaaccgact cctcaccgac ggaatggccc gggccggcct
     4321 cggggactac atcacctcgt cggacttcgg cgtcgacgtg atggagaact ggcagtccga
     4381 atacctccag ttcttcctct acatcttcgc caccgtgtgg ctcgtgcagc gcggctcccc
     4441 ggaatcgaag gaactccaca aggccggaag ggagtccgac gaggaccaga tggtcggcga
     4501 gcgcgcccgg gacgactcac ccggctgggc ggcgtcccgc ggctggcggc agggcgccta
     4561 cgcccgctcc ctcggcatgg tcatgggcct gatcttcctg ctgtcctggc tcgcccagtc
     4621 catcaccggc accgccgccc acaacgaacg ccggctcagg cggctccagg cgcccaccag
     4681 ctggtccgag tacgtgttct ccgcggactt ctggagccgg accctgcaga actggcagtc
     4741 cgagctgctc gccatcggct ccatggcgat cctctccatc tacctgcgcc agcgcggctc
     4801 accggaattc aaacccgtcg gttcgggcca cgccgaaacc ggcgtcgagg gctgaccgtc
     4861 caccggtgac cgccgtcgcc ggcgcgtccg tcgccacgag cgcggcggaa cgacggcggc
     4921 ctcggcgggc ccgaactgct cctcgtcgtc ctcgatctcg aaccagactc cggggaagtc
     4981 accgtcttgc ggatccggca cgacccgtcc tttcccgact cacgtcgtta tgcgggcgtt
     5041 cctactcgct catgcccgtg gctcagcttc ggcctcacca ccatgaggtg agtttctccc
     5101 cgatgccctc accggcgaag gcgccggcga tgccgcccgc gataccgccg acgatgccgc
     5161 cgacctcccc ggcgccggag cggtgatccc ctgtgcgcgt cgcccaaagc cccgccccgc
     5221 cccgccccgg tgccgctgcc ggtgcggccg ggccggggca ccggccggtg ggccccgagg
     5281 tggacaggag gcgacgccgg cccgcgaggg gcggaggcac ccctgatcag taggcacctc
     5341 ggtgtggtcg attccgggca ctttcggcgc ctgccattgc cgcagtcgat cagattgcgg
     5401 ggccatgtcg tcaaagagcg ccgctgcttt cagcaaggtc acatggccaa cccgatctga
     5461 ctatgctccc ctccgatgtg tcgcgctgcg ctcacagtgc gtgatcaacg ctgtgtgcct
     5521 gcggacggag cccgaccgcg acgaggcgtg actgtcgatg cgatctcgaa gcgaaccgtc
     5581 gggggcattc caccggaaac gtgtgttcag ccgtgtgaag cccgcccggt cctgccggcg
     5641 caccgcatca cctcagccca ctcattccga ctgtttaggg aacccctcga tggttcgtgc
     5701 aggttcaact tccagggccc ggccacgcgc agtggctctg gtatggctca taccccctgg
     5761 tgctctggct ggggcttttg ccatggcgct gatcttcgtc cctgcgcaga cacggacaac
     5821 cgtcgcctgg tgcggtcttg ccgcggtcgt cctgacggtc ctcacctcgg ccgggacggc
     5881 gcgccggacg cgcgcggtgg acgcggcccg ctacgagcag gcgagtaccg aggcgcaggc
     5941 gtacttcgcg caacgcgagg ccgcactgat cgggcgcctg tccgatcagc gggccaccac
     6001 cgtgtggctg gccgaggagc ttctccccgc ggcagtcgcc cggctgcaga agggcgaccc
     6061 ggcctcggag atcatgcagt ccgtcaggtt cggggaacac ctcgacagcg agttcaggga
     6121 agcgctccgg gcagctctgc ggacactcct ggaagccgtg gaggccgagg agcacacacg
     6181 ggactcctcc cagcgagcac tggtggccat cgcgcgccgg gtccaggcga tcgtgcatca
     6241 actcgccaag gacctccggt ccatgcagat cctccacggt acggatgtcg tggtctccca
     6301 cggcctgcag gacatcgacc accgcaatgc cctgatcggc cgcctcgccg ccagcatcgc
     6361 ggtactgggt gacgcgcggc cggggcgcca gtggtcgaag gcgatcccgc tctacgacgt
     6421 cctgcgtggg gccatgtcac ggatcgtgga ctacccccgc gtgaaactgc agtcggtgac
     6481 agaggtggcc gtgatcggcc cgggggccga accgctgatc cacctgctcg ccgaactgct
     6541 cgacaacgcc acgaccttct cgccgccgga cacccccgtc gacgtgaccg cgagcgaggt
     6601 gccctccggc atcgcgatcg agatcgagga ccgaggggtc ggactcaccg aggaagtccg
     6661 gcagcgcgtc gaccgcgtca tggcccagtc gtcgtccggc atccaactgg ccggcctggg
     6721 cgaggtgaca caactcggcc tggccgtcgt cagcaggctg gcccgcgagc acggcctcga
     6781 cgtcgacctg cgcacctccg cctacggagg cgttcgggcc gtcgtgctcg ttccgaggag
     6841 cctgatcacc acggtgcagc agcctgccgc gaacgccgcc ctaccgcccg cgcggaagca
     6901 cacggacgga ccgatcgtgc cgagacagac gccaccgggc cctgacgcat cggatgccgt
     6961 cgaggtcagg gcgaccgtca acgggctccc gcaacggcga cgcgagtcac ccgtcccgaa
     7021 accggtcgtc cgcaccaccc cccatccccc cgctgctccg gccgcctccc cgggaaacaa
     7081 cggaatgccc cggcaaccgg gcctgatgtg ggaggcgttc aacggcgaca agagatcgag
     7141 cgccgaacct tccactgaaa acagcgagtc atcagatgag ggtgagtaac atgcagccac
     7201 tgcccaacat tgactggatg ctcaaggagc tcacggccag cgtcccgtac gtgcggcacg
     7261 tggtcgtcct gtcgtccgac ggtctgtgca tcggtcaggc ggacacggag cccgacaccg
     7321 ctgatgggat cgccgccgcc tgctcgggca tccagagcct ggcgaaggcc atcgcccaga
     7381 agttcccgca cggggacggc tcgacgcgga tggtcgggat cgaggtcgac ggcgggtact
     7441 tctccctgat ggcggccgga cccggcgcct atctcgcggt gctggccgac gaggaagtgg
     7501 acgccgggct gctcggcgac cggatgcgga cgctcgtcgt ccggatcggc cagcacatga
     7561 ccagcccgcc ccgcgatgac gtcgggcggg cgatgtgacg tcagagaacc aggacacatg
     7621 ggacgaaggc agtcccgtgc cgctcttcgt catcaccggt ggcccgggtt cctcggccga
     7681 ggccttcaac ctcgtcaccc tcatcgcagc gaggtccaca ccggaacccg gtatgcagcc
     7741 cgaacaggcg gcgatcgtct ccatgtgccg atacccgctg tcggtggccg agatctcggc
     7801 gtatctcagt cttccgttca gcgtcgtcac ggtgctgctc tccaaactcg tcgacgacgg
     7861 ccgggtcgag gccaccgctc ccgtgcccgt cgcgtcatac cccgaactcg gccttctgga
     7921 ggcggtgatc catggactac gtaagctctg acgcacccac tgccggcccg cgcggcaccg
     7981 acgtgctgct gccccacggc gccaggggag tcaaggtcgt gatcgtcggc ggcttcgggg
     8041 tcggcaagac gaccatggtc ggatcggtga gcgagatccc gcccctgacc accgaagaga
     8101 ccatgaccca ggcgggcgtc gggatcgacc acaatcccgg agccgaaggc aagagcacca
     8161 cgaccgtcgc catggacttc ggccggatca gcatcaaccg ggaactgatc ctctatctct
     8221 tcgggacccc ggggcaggag cgcttctggt tcctgtggaa cggcatcttc gagggcgcgt
     8281 tcggcgccgt cgtccttgtc gacacacgca ggatcgatgt ctgcttcgag gtcatcaccc
     8341 ggctcgagga ccgccgggtc cccttcatcg tggccgtcaa caccttcccg gaggccccgc
     8401 agcaccccat atcagccctg cgcaccgctc tggccctcaa cgagtccgtg cccatcgtca
     8461 cctgtgacgc acgtgatcgg tcgtcctgcc gcgacgccct gctctcgctg atggtctatc
     8521 tgcgcaccct cgccgccgct caggagtccg catgaccgtc ccaccggctg aacacaccac
     8581 cccgcagggc gggcccaccc cgcccccggg ctgcccggcc cacaccaccg caggagccgg
     8641 cggagtgacc cggctccacg gcgccgccgc cgaaaccgac cccatgggcc tgtacgagaa
     8701 gctgcgcgcc gcccacggtc cggtggcgcc cgtcctgctc gacggcgacg tacgggcctg
     8761 gctcgtcctg gggtatctcg agaaccgcga cgtggccagc cgctccaccc agttctcacg
     8821 cgacccccgc acctggcacg gctggacgag cggagagatc gaccccacca cctcaccgct
     8881 gatgccgatg atcggctggc gtcccgactg cgtctgtgcc gacggcgaag aacaccagcg
     8941 cctgcgcggc gcggtcacgg ccggcctcga tcagttcgac caacgcggaa tccgccgcca
     9001 catcacccgc ttcgcgcacc agctgatcga cggattctgt gaaagcggcg aggtggaact
     9061 ggtcggtcag ttcaccgaac acctgcccat gctcgtactc acccacctgc tcggaatgcc
     9121 ggacgagtcc ggtcccaagc tcgtgcatgc cgcccgcgac ctcttcaagg gcaccgagac
     9181 gtcgctcgcc agcaacgcct atgtgctgga gacgctcgag caactcgtcg tcaccaagcg
     9241 cacccgcccc gggcaggaca tcgcatccgt actgatgtcc catcccgccg gcctgacgga
     9301 cgaggaggtg cagcaccacc tgcgtctcat cctgctcgcc ggctatgaga caaccgccaa
     9361 cctcatgtcc aacgtcctgc ggatggtggt caccgacccg cggttccgcg ggtccctggc
     9421 cggcggtcag atgaccctgc ccgaagcggt ggaacaggtg ctctgggacg agccgccgct
     9481 gatggtgtgc ccaggacgct gggccaaggg cgacacgtcc ctcggcggac agcagatcaa
     9541 ggcgggggac atgctgctgc tgggcctggc cgcaggcaac gtcgaccagg cggtccgccc
     9601 cgatctctcc acccccgtgc accacaaccg cgcgcacctg tccttcagcg ccggcacaca
     9661 cgagtgcccc ggccaggaca tcggtcgtgt catcgccgac accggcatcg acattctgct
     9721 cacccggctc cccgacatcg ccctggccgt cccggagtcc gagctcacct ggcgctcctc
     9781 cacctgggcc cggcatctga cagcgctgcc ggtgagcttc gcgccccgtg ctcccagggc
     9841 ccatgacgtc ccggcatcgc tgccggcccc gccgtcgccg accggcgggt tgcccgcggt
     9901 acccccgcgg ccggtggccg gccccctgcc ggagcgcgca ccagaacccc gcggttcgtg
     9961 gtgggtgcgg ctgcgacgcc tcctgcggag acggtagacc tcacgggttg gcgtcacagg
    10021 ttcgcatcac agccgaggtg gaggtgcgtt gctccgggaa cgggatgtct gcgggaacgt
    10081 agcggggcgc tccggtgtac caggaatgga ggcccgacag gaagccgcaa gctcctcgga
    10141 gccacgtctc cagctcggct tgctcaccgg cgtgcagccc ggctcgttcg acgagcaggg
    10201 gcagttcgct gtgcctgagg tgctcgaagt ggcgcagtcg ggcgttcacc agatcgacgg
    10261 cggcccgcac cgcctcctgg atggtgatgc ccatggacgt cgcgagtacc agcacgaggt
    10321 tgttgacgtc gcgttcctcg tgtacttcgc gccgatagga ggctatgtcg ttggccagcc
    10381 ccatgtagtc catgaaggcg tcgagcagag cgcggacggt ccggctgtgc cggatctgct
    10441 cagggatccg cgcgccggtg gcaagctcga cggagtaggg ggcggtatag gcggcgaagc
    10501 tttcacggcg gaactgggcg tactcgatca ggtccggaac ccggccggcg cggctgttgg
    10561 ccagttcctg gactcccgcg tcgatgtatc gcgccagggc ctggttgaac ccgtgccgcc
    10621 agtgtgcgag tcgagggggg aacagatgcg gctgcagatc ggcgattccc ctctcgaccg
    10681 cattcgtcgg ctccggtaac cgggcgcccg gctccggccg caggaaggca tggagccgtg
    10741 aggtgaagac cagtgcgccc gcgaggtcgc ccgtccgttt gaaggcggag gcgaagtagt
    10801 cgtcccaggc cagcgcccag atgttgaacc ggtggttgag ccggagagcg gcgagtgagg
    10861 cgtcaggaag agtggaggcg gtcagttggt cgacggtcat ggcgtggaac tgggaccggg
    10921 accagatcgc acggcgagcc gtcggtctct cgtcgccgcc gagcatgccc atctcccgcg
    10981 cccacgtctc ggtctcctcg cgcagggccg gcaggtacgg attgaccctc gccggatggg
    11041 gcatccacag tccggggagc ttgacggcct gcactgtcat gggaaatctt ctccttttcg
    11101 cctgcatcgg tgtgcggatc accaccgcga gcggccgacc ggtgaaggca gcgcgctttt
    11161 gtcgttcgca ccgcgcctcg ggagcatgag caggtcgtgg acagcacgtc ggaccggcgc
    11221 gtcgcatctg ccccggcacc ccccatgctg tgacgaccgg ccgtcagggc acgggtcggt
    11281 tcccttcctg tggcgcccca aacctgccca cccggtcgac gcgcaacctc gcgcggctgt
    11341 cctgggcttg cgatccgaac agtttgtagg gaattggcga tccgtgcagg gcagtttggc
    11401 gcaaattcga tcccaaagcc gaccgtgatc aatcaatcat cgccagtgga cgcgcagcgt
    11461 ccgaaaacct cggctcgaac cgcggtcgac gtccacccgc tgaagaagca ggcgggaggg
    11521 ggcgagtaac ggccggtcgg tgttcgggtg ggcacgcgaa ggccggtgtg tcggccggtg
    11581 tgtccgccgc gccggcctgc gctccgcgcg agggccgggt gtcaggcggg gggcgccaga
    11641 aggccgtcga cgatacggcg gaccttgttc accgcgtcgc tgtcaccggt ccgcagtgcc
    11701 gtgttggcgg cgcagagcag cgcgtcgatc tggaatgcgg tgagctcgac gtcgagatcg
    11761 gtgatctcgc cggagtccac ggcgtgtccg agttcggtgg cgatgactcc gcgccactcc
    11821 tcctggtcac ggaagagaga gtcgcgaacc ggccccggcc ggctgtcgaa ctcggcgagg
    11881 ttcgcggccc ggaagcatcc gccggcgaac agaggcgtct cggcgtagac gatccagtgg
    11941 tcgagcagag cgcggaggcg ggccgtgccg cggcgtgccg acgaggcggg gcggacgacg
    12001 gcgtcgatga acatctcgcg ggcgaagtcg accacggcga gttgcagggt ctccttcgtc
    12061 ttgaagaggg tctggatacc ggccttgctc agtcctgtgc ccgatgcgag gcggccgaag
    12121 ctgacgccgc tcagtccttc gagggaggcg atgtcgacgg cctgccggag cacggtctgc
    12181 cgggtccggg cgccgcgcag caggcgcttg tccgtgatct ccgtccgtgc cctctccgag
    12241 gtcagcggca cctgcggtcc ggcaccaccg gcccctgagg cgaccggctc ctcgaaactg
    12301 tccatacggt cgatcgtacc ctcttcggca gtgccgagcc gggctcccgc cgtggcgggg
    12361 gtcgtgggat gcgtcaggcg cggggtgtac ggctgagcac gccggccagc cccttcacca
    12421 tctcggtcgc catcaccgcc tgccccgagg tcgagaagtg aatccggtcc gcactcagga
    12481 ggccgtgacg gtcgttcacc ggatggtccc acatgtcgac gaccacggcc ccgtactcgt
    12541 cggccagggc gcgggtgatg tcgttgaccc tggtgacccg ctcgctccag tcggagaaga
    12601 cgggcacgac atacgcccgg ccgagcgtga acgtggtcag ttgtgccccg gtccgggacg
    12661 ccatctcgta catccgccgc agcgtccgcc cgatctcgtc gaagtcgggc cggcggcgag
    12721 ccaagtcgtt cgccccgcac ggcaggtgga gcaggtccgg ggcgaattcc agcaggcggt
    12781 cgatctgctt ctcgagtgtc cgcgaagtgg tggccccgat ctcggcggtg ttcaggtact
    12841 cgaggtccgg ccgtacgcgg cgcaggatgt ccgcgatcct gtcggaccag cccgcgtccg
    12901 tatagccggg actggcgtcc ccggtccccg ccgaaaggct gtcaccgatc acggcgaacc
    12961 gggaccaggg agtgtcgaag agaagcgccg ccgcgtcgag cggaggcagg cagaacgggt
    13021 cggactcttc ggtgagttgc gtcgcagtca tggaaaaaac aatacggtcg tacgtatgta
    13081 atggcaatcc tgatgcctcc gagaatgccg cagtcagggg gaacggcgac cggctcggtc
    13141 agggggaaac ggccccagga cgctgatcag cttctgcttc ggcgtgcccg gtcccgtcca
    13201 cgccgatact cccggtgaac aggccggaac cgggtcgagg cgggcaggtc cgagccggtc
    13261 cgctcgcgcg tcgtcctaca gccagccgtg gcgttcggcg atccggacgg cgtcgaggag
    13321 ggtacgggca tggagcttgg cgacagcgga ggagagccgg ttgcggaccg tgccgacgct
    13381 caggaagagg tcggcggcga tctcgcgggc atgcgcgccg ttggacgcca gtcgcagtac
    13441 ctcggcctcg cggtcggtca tggggctgac ctcgccgacc cagctgtccg gcatccgcga
    13501 gtcgatcact cgcccgcccc cggcgaccct gcgaatcgcg tccgcggtct cggcgggggt
    13561 cgcgctcttg agcagataac cggaggcgcc cgcgtccatc gcacggcgca gatgtccggg
    13621 ccggtccagc gcagtgagta tcaaggtgcg acagccgggc agccgctcgg cgagggtggc
    13681 ggcgacggtg atcccgtccg tgacgggcag gtcgatgtcg aggaggacca catcgggcct
    13741 gagcctttcg gcctcggcga gtgcggcggg cccgtcggcg gcctggccga cgaccgccat
    13801 gcccaactct cccgagagca gcgccgtgag cccggaccgc acgacggcgt ggtcttcgac
    13861 taccagcact gtgatcaccg atcgattatc cccgtaccgc ggacgcggcg gacggggcgc
    13921 ttccggccag ccacgccctt tgtgtcggcg agccataatc gaccgggaac gatcaaggta
    13981 ggggcggggg agagggtgcg aatcgggcca gtggacgacg tgacggctcc accgggagca
    14041 cgggtcgctt tcggcacgct ggtggtgctc gtggtcggaa cgctcggact ggtggcgctg
    14101 gacgtcgccg cttcgccgct cggcaggcgc gcgatggtga ccggtctgac cgtgctggtc
    14161 ctgatgcccg ccgtgctgct cggccagtac gtgccaccgc cctaccggtt gtcgcgtcgc
    14221 tggaggtggg gcctgctgct ggctcaggct gcactcacgt acctgccgct ggtggttttc
    14281 cactacccct ggcttactct gctcggcttc ctcgccggcg ccgtgctcct gaccctgccc
    14341 cctgccactt cggtccccgt tgctctggcc gtcggcgcca gcgggccact gctgatccac
    14401 acgggcgtca tcgacaccga ccgtggttct ctgagcgtcg tcctcagcac ggcgatcacg
    14461 gcgagcgccg tattcgcggt cgcccatctc gccctcgtgt cggcgcggtt gcacggagcc
    14521 agggagcaga cggtcaggct ggcggagcag cgcacccggg cacgcatgcg gcaggacctg
    14581 catgatctgg tcggctcgtc gttggttgcg atcgtcatcc ggggagaggc cgccttgcgg
    14641 gcagatgttt ccgccgcgtc cgcccgctcg gtactcgccg aggtcgttgc gcttgctcgg
    14701 cggacccatg aggacgttcg gctcatcagt ggcccggaga cgaccctctc actggctgaa
    14761 gagtttgctc acgcccaacg gctgctgacc agcgccggga tagcggtgcg cacctcgctg
    14821 cccccgcacg tcgagccgga ccgggcggtg gtgaactgtc tccggtcggt cctgcacgag
    14881 gcggtcggca acgtgctcga gcacagcaga gccggcttct gcgagatcga gctgcgggcc
    14941 ggcgacgacg acatccggct gaccgtccgc aacgacgggg tcgccgccac cggttcggtg
    15001 ccggccgctg tgcggacggt cgggcaccga ggaacggggc tggtcgggct caagggccgg
    15061 gtcatcgcgc tcggtggaac actgcacgtc ggcccgacgg gccgggagtt ctccgtcgcg
    15121 gccgttctgc cactgggccg agacggggcg tagcccccgg tcccgggctc cgaacgccgg
    15181 acttccggcg ggaacacgcc aggccgtggg cgcccggcga ggtgtgaggg ttgtgcgccc
    15241 agaccgtgaa gatctcactt cctgcgcagg tacgcaggtg atcggatcca cttgatttcc
    15301 gttcctccta agagagttgc tgatcaatga gtgatggatt ctctcgccgc agtgcgcggc
    15361 gaggaacacc gcaggccctg caacgccgca gacgggtcct gcatcggata gccatgagca
    15421 cggccatggt gctggcggcg gagacgggcc tcgtactgtc aggtacgggg caggctgtgg
    15481 cgcttgccgc cgtacctgcc caaccggtga acgcatcgaa gcccgcggga acaggcccct
    15541 cgcaagccgc cgacattccg tcggccaagg tggctgcccg gctctacggg aagcgcgtcg
    15601 aggcgctgtc ggaacggacc gaggcgtcga cgacatgggt gaacaaagac ggttcactca
    15661 cgacggagct gtccgcaggc ccgatccgat tccagcgtga cgggcaatgg gtcgatgtgg
    15721 acgtccggct ccaagcgggc tcctcgggtt cggtcgaggc gaaggcgcac ccccatgggc
    15781 tgaaactggc gggcaggacc ggcaccaggg ccgcgtcact gcgggccgcg caggacgcgg
    15841 cagcagtcga cctggtgacg ctgggcagtg gagaggagca gatcaccctc cagtggaagg
    15901 gcggcctgcc gaagcccgag ctcaccgggt cgcgggcggt gtatccagag gccgtaccgg
    15961 gagccgacgt ggtggtcgag gccacccgta ccggtttcga gcagttcgtc gagatcaaga
    16021 agcgcccggc gtcggacggc tacacgtaca cgctgccctt gaagaccaag gggctgaagg
    16081 cgaagcaaca ggccgacggc agcgtgctct tcacggacaa gaagacgaag aaccggctgg
    16141 tcatgccggc cccggtgatg tgggactcca cagtggatcc ggtctccggc gagcacaccc
    16201 gccgggtgcc ggtgtccatg aaggtcaagc agaggggaac gtccgtcgat ctggtggtga
    16261 caccggacgc cgagttcctc tccgacccga agaccaaata cccggtcacc gtcgacccgt
    16321 cgacatcttc cctgtccaac gtcttcgaca cctatgtcca gcagggtgag acccgggact
    16381 ggtccacgga cacggagctg gatctcggaa accccggcac caccaacccg gacggcacgc
    16441 cgcggatcgc gcagtcgttc atctcgtgga acaccacacc ggtgcaggat gcactgatct
    16501 ccagcgcgaa gctgagtctg tggaacttcc actcaggcaa cgtcgactgc aagccctacc
    16561 cgtgggaagt ctggtcatcg ggcgcggcgt cgacgtccag ccgctggacg aaccgtccca
    16621 ccatgacggc gaagaaggcg acctccaccg agacgcgggg caacagcgcc tgcaccacgg
    16681 caccggacgg ttggatcaac gccgacgtga cgaccctggt gcaggaatgg gcctccgcga
    16741 aggcgacccg tggccacatg ggtctgcgcg cctccagcga gtcggtggtc gcccagtgga
    16801 agcgggtcaa ctccgccaac gccgcgtcga acccgccccg gctggtggtg aactacaact
    16861 accggccccg gagcggaacc aaccaggaag ccggtccgcc gttcttcacg tacggcggcg
    16921 cctacatggt caacaccgtc accccgacgc tccgggacac cttcgtcgat ccggacggtg
    16981 acaaggtcaa cggcaccttc cagatcttcg acagcgccac caacacccag gtgggcaatg
    17041 ttctggtctc accgtacgtc ccctccgggc agcaggcgtc cgtgacggtg ccggccgggg
    17101 tgctcgcgga gggcaagacc tacaagttcc gcacgagccc ctacgacggc acgcactaca
    17161 acacgggctg gtccgcctgg aagacattca ccgtcgattc caaggctccg tcggccccgg
    17221 ccaggatcac atccgccgac tatcccgcgg acgcctgggt gaagggggcc ggccagaccg
    17281 gcacgttcac cgtcacgcct gcggcagccg atcacaactg gctggagtgg tcgctggacg
    17341 gagtcacgtg gacgaaggtc gccaccggcg gtgccaccgc cgacaaggcc atcagcgtca
    17401 cgccgtccaa gaacggaacg cagacactgc aggtgcggtc ggtcgacaag gccgacaaca
    17461 gttccgaacc gctcgactac accttccatg tggggcccgg aggcatcctc cagccgtccg
    17521 agggtgagcg gaccgcacgc cggctgcctc tggtcgccga ggccgaggcc ggtaagtacg
    17581 acaaggtgtc gttctcctgg cggcgctccg atgccgacgc ctgggcgccc gttccgacgg
    17641 cacatgtgac cgccgccggc cagccgctcg cctcctggcc ggtgcccctg gtcgacggca
    17701 agaacgcggg cctcgtgtgg gcggccaccg aaacggtgga cccggacggc agcatccagc
    17761 tcaaggccga cttcaccggc cccgacgcgg cggccagcag tacccctccg ctgagcgtcg
    17821 tcgtcgaccg caacgccgaa ggcgcggagt ccaccggcat cggccccggg catctcaacc
    17881 ttctgacggg tgacttcagg ctcaccggca cggagcagag ctacttcgac ctgtccgcgt
    17941 cccgtacggc ctcgtcccgt cggccgaccg ctgccacggc acaggaagga caggcgccga
    18001 tcttcggcaa ggagtggctc tccggcacgc tcgccgaggt ctctcaggcc ggttacacac
    18061 acatccgcag gacgtccgcc acatcactcg acgtcgtgat ggaggacggc acaaagatcc
    18121 acttcacggc ccgggccaac acgcccggcg gctgggtccc cgaacccggt tccgagatgc
    18181 tcaccctgac cggcaccttc gccggcggat tcaccctcat cgacaccgag ggcgccgaat
    18241 ccgtgttcgc gaaggtcgat tcggcggcgg agacctggca gatcacttcg tcgcgtctcc
    18301 agggcatcga gaactccacg acgaacatga tctccgagcc cgtcgtggtc ggcacgaaga
    18361 cgctcgcccg gccgcgcatg ctgatctcct cccacggggc ggtggcgaac agcacctgcg
    18421 ccaagacacc gtcgaccagg gggtgtcgtg ttctggagtt cgtgtacgcg acctcgacga
    18481 cgggcacgga cgccacgccc ggggacttct cgggccagct gaaggcactc aagctctggt
    18541 ccacggaggc gggtgcgtcc gcggctacgg cgaaaaccgt ccagagctac gcctacgacg
    18601 ccgccggccg gctgcgcgag gcctggaacc cgctgatcac cccggcgctg aagaccaagt
    18661 acgcctatga cagcgccggc cgcgtcacgc aggtcaccgc tcccggccag ctgccgtgga
    18721 cgatgacgta cggaaacgcc ggcggaaccg cgggcgggga cgggatgctc acctccgtca
    18781 ccagggcgac gctcaagcag ggcaccaagt cgacgacgga cggccaggcc gtcacgtcgg
    18841 tcgtctacaa cgtcccgatc accggcgccg acgcaccgca cgccatgggg gcttccgacg
    18901 tcaaggcatg ggggcagctc gacgctccca gcgacgcgac ggcgatcttc ccgcccgatt
    18961 cggtgccgcc cacctacaag ggcggcgcac tgggcgccga cgggtaccgc cgggcggagc
    19021 tccactatct cgacgcctcc ggccgagagg tgaacaccgt cgacgaagcg ggagggatca
    19081 ccaccacgga gtacgacctg cacggaaacg tcattcgtga gctgagcgca ggcaaccgcg
    19141 ctctggcact cgggaagacc gacgaggaga aggcgcgact gtccgacctc ggcatcgcgc
    19201 tgcacagcac ggcggagcgg gcggccctgc tctccggcac ctccctgtac aacagcacgg
    19261 gaacgcggct gctggagcag ttcggaccgc ttcgccgtgt cgacctcacg gaggacttca
    19321 aggacggcac caccgtcctg atccccgccg gcacctcggt ggcggcccag ccctggaccg
    19381 tgaccgagta cgacgagggc aggcccaccg acggcagcgc cgtcgccaag gaccagccga
    19441 cgctgtccat cgtgggcgcc agggtccgcg gccactactc ggtgatgggt gagaagcgac
    19501 tcaccgagac ccagtacgac tgggccaagg gccttccggt cctgaccatc gaggacccgg
    19561 gcgggctcaa cctgaccacc agcaccgcgt acgacgccca gggccgcatc actgccgtgg
    19621 tcccgccggg cggcacgggc caggacgcga cgtccaggat cgtccagtac tggtcggcca
    19681 ccggtacggg ctggtgcgaa ggacgcccgg agtgggtcgg actggagtgc tgggcgggtc
    19741 ctgccggggc gatcaccggt ggcgggagcc agcccaccga ggtggtcgac acgaccaccg
    19801 agtacgaatt cttcgggcag ccgacggaga agaccgaaac cgccaatggc gtgacccgga
    19861 cgaccacgac cgtcttcgac ggcgccggcc gcgtgaagag cgtgcaggtg gacggaggcg
    19921 tcggcaaggt cgtcgcgggc acctccctca cctacgaccc cctcaacggc tcggtgatca
    19981 agacggcgtc ggcggacggc ggcagcatcc ttcaggagta cgacgacctg gggcgtgtca
    20041 tctcctacac agacgccgac aacggcgtca ccaccactga gtacgacgcc ttcgaccgtc
    20101 cggtgaaggt ctccgactcg gtcccgtcca ccactacgta cacctacgat cacaccgctg
    20161 agccccgcgg cctgcccacg gcgatgaacg actccgtcgc cggcacgttc cgggcgacgt
    20221 acgacacgga cgggggcgtc gtctcgcagt cccttcccgg cggctacacc atgacccagt
    20281 cggcgggcaa gatcggaatg ccctaccagc gtctctacac cagggattcc gacggcacgg
    20341 ttctcctgtc cgattccgtc gccgagacga tccacggcga atggtcgcac catgcgggcg
    20401 gcgccggcat gggcgaggca caggacttca cctatgaccg gatcggccgt ctcaccaagg
    20461 tggccgacac ctacaacgga gcatgcacgt cccgtacgta cggcttcgac aagcgcacca
    20521 atcggacctc gctcacgacg gccgtcggcg cccccggcgc cgagtgcccg acgagcgggg
    20581 gcgagacggt gacgtccgcg tacgacagcg ccgaccgtca ggtcgacccc ggttacacgt
    20641 acgacgcgtt cggacggacg acacggctgc cggacggcac gacgatcgcc taccacaaca
    20701 acgacctcgt ccagcagcag acggttggga actcccgcca gacgtggtcg ctggacgcat
    20761 cgggccgtat acgcggctgg acgacggagt ccaataccgc cggcagctgg aacccgaccg
    20821 gcacgaagac gaaccactac ggcgacagtt ccgacaaccc gcgctggatc accgacagca
    20881 acggttccgg tgtggtccgt atggtcggcg acctggccag tgccatgtcg gccacgaccg
    20941 gcaagtcggg ggaggtctcg ctgcagctgt ccaatctgca cggcgacatc aacctcgtcc
    21001 ttccgctgga cacagcgctc gcaccgacgg ccctgagcag cgacgagtac ggcaaccagc
    21061 gcatgccgga agcccctgtg
//
