LOCUS       NZ_CP107567            22540 bp    DNA     linear   CON 18-NOV-2023
DEFINITION  Streptomyces peucetius strain NA0869 chromosome, complete genome.
ACCESSION   NZ_CP107567
VERSION     NZ_CP107567.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces peucetius
  ORGANISM  Streptomyces peucetius
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8050611)
  AUTHORS   Zhao,E. and Ge,H.
  TITLE     Cytochrome P450 Catalyzes Benzene Ring Formation in the Biosynthesis
            of Trialkyl-Substituted Aromatic Polyketides
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8050611)
  AUTHORS   Zhao,E. and Ge,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2022) School of Life Sciences, Nanjing University,
            No. 163 of Xianlin Avenue, Qixia District, Nanjing, Jiangsu 210033,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: unicycler(0.4.8) v. v. 3
            Assembly Name                     :: NJU_NA0869
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/18/2023 06:49:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,216
            CDSs (total)                      :: 7,126
            Genes (coding)                    :: 6,825
            CDSs (with protein)               :: 6,825
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 303
            CDSs (without protein)            :: 301
            Pseudo Genes (ambiguous residues) :: 0 of 303
            Pseudo Genes (frameshifted)       :: 144 of 303
            Pseudo Genes (incomplete)         :: 227 of 303
            Pseudo Genes (internal stop)      :: 22 of 303
            Pseudo Genes (multiple problems)  :: 85 of 303
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:23:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3588364
            Orig. end                         :: 3610904
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP107567.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from IFB-NA0869, Nanjing
            University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22540
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="11"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22540
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22540
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12540](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12540)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            407..1747
                     /locus_tag="OGH68_RS16330"
                     /old_locus_tag="OGH68_16330"
     CDS             407..1747
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005315757.1"
                     /locus_tag="OGH68_RS16330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16330"
                     /product="MFS transporter"
                     /protein_id="WP_264244744.1"
                     /transl_table=11
                     /translation="MNRPLDPRAARRRFVAVTFLFWLPVGLYIPSQVLLLTERGMSLAV
                     VAGLFAVHSVTVSVLELPTGGLSDVVGRRAVLAAAGLLNLSALTVMALGTTVWALAVAM
                     FLMGSGRALSSGPAEAWYVDTVQAHSGPGAELRTGLARGNTASAAALAAGTLLGGALPL
                     LLGLGTDPGARLADATGGLVLPLSVPGLLGAAVGVGYVAYVLTALPEPPRPPATLRGVL
                     RGVPATMLGGLRLGVTEPLVRRVLLTAAAAGAALATVELLTPGRAARLTGAPESGAVLY
                     ASLACAGFLCTAVGSHCAPPAARLTGSGEHAVLAALGVSTTGLALLGVTAAWDGGTAPL
                     VLAAVGYGLVYLGLGAAGPNENDLLHRRVDSTVRATALSVKSLALQSVAALTGLVAGSL
                     PIGPLPWLVGATALLLGALLWIRRAKPVPAAAPAVSGLTATESVPGR"
     gene            1757..3343
                     /locus_tag="OGH68_RS16335"
                     /old_locus_tag="OGH68_16335"
     CDS             1757..3343
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009327027.1"
                     /locus_tag="OGH68_RS16335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16335"
                     /product="serine hydrolase"
                     /protein_id="WP_264244746.1"
                     /transl_table=11
                     /translation="MVLQRPVGHRRRRAPGAVLLASLLVATGATAAGAAEPPPPPPPQL
                     TDKQVDDAVAKLDGIVRDGMKRTGVPGVAVAVVHKDRVVHIEGFGERETGKAGAVSPDT
                     VFQLASLSKPLASTVVAGAVGDKAIAWDDPVAKHVPHFALKDPWVTEHVTVADLFSHRS
                     GLPDHGGDLLEDLGYDRDYILSHLRHLPLAPFRASYAYTNFGLTAAGVAVAEASNTDWE
                     KLAEDTLYSPAGMNSTSSRFDDYEKARNKAVTHVKEGDTWKARYVRDADAQSPAGGVSS
                     TAEDMATWMRLQLANGKLGDDRIIPAGPLTRTHEPAAVAQPPAAPTDRTGFYGLGWNVG
                     YDDQGRLRLSHSGAFGLGANTNVTLLPAEQLGIVVLTNGEPVGLADSVAFNFYDTAQYG
                     KPTGDWLARIGQVYQQEEQEARSPTDYGRPPPDAADAQPDNTYTGTYRNDYYGTLRVTA
                     SNGELTMELGPKPLRFPLAHYDGNTFSFMTVGENAVGRSGVMFTVDSDAKASKVRVESL
                     DKNGLGTFTRQ"
     misc_feature    3480..3498
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.55"
                     /tool="antismash"
     gene            3505..3729
                     /locus_tag="OGH68_RS16340"
                     /old_locus_tag="OGH68_16340"
     CDS             3505..3729
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002683.1"
                     /locus_tag="OGH68_RS16340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16340"
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="WP_264244748.1"
                     /transl_table=11
                     /translation="MALTHIDIDDEALETAKRLGGHRTKTAAVAKALEEYNKRLLRAAA
                     YKKYFEIAQDWDIEAAEAAHKADKETFGR"
     gene            3726..4142
                     /locus_tag="OGH68_RS16345"
                     /old_locus_tag="OGH68_16345"
     CDS             3726..4142
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143914.1"
                     /locus_tag="OGH68_RS16345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16345"
                     /product="PIN domain-containing protein"
                     /protein_id="WP_264244749.1"
                     /transl_table=11
                     /translation="MNVYLLDSSALWRMLRERSLHTTWQDTVLEGDVRSCYPQRVEFLR
                     SARDAKEYEAYSAMFAELYDDVPVPKSAAHWVGGLQTRAAPHGAHHALSAVDLQICSTA
                     AHHGLIVLHDDRDFVTAARFAVELQQHNVHDGPR"
     gene            complement(4148..5140)
                     /locus_tag="OGH68_RS16350"
                     /old_locus_tag="OGH68_16350"
     CDS             complement(4148..5140)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005315752.1"
                     /locus_tag="OGH68_RS16350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16350"
                     /product="hypothetical protein"
                     /protein_id="WP_264244751.1"
                     /transl_table=11
                     /translation="MTFGGQNPYRRTGQPQPGPPPRPGVPPQPGPYPGPPLPYRPYGPR
                     PTLWQRFREDEWPPLRELLHELRRVPGCLLALGMCCVWPALAVLIGYPLARSARRQARR
                     KFPAHSIRRYHDPEVWRVQKARAWGALGASFLILVAYGTEADWNEVQEQYFFRLAITPW
                     LLLLTTPFVLLVLFRLAPPAARPGMRARLRPAVRSVLWYFGAFTAVPLLFAGVMLLSES
                     YASSPLSPLVTLALLLPVLWVLFFVVFASTTAVRTAFSTAEVHAALPALLTGVLVWELA
                     VVNLTTAGMPPGPPAVQICAVIGGPASVTAIAWWELTRLRTRYGVTLRG"
     misc_feature    complement(5030..5032)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5136..5151
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(5216..5428)
                     /locus_tag="OGH68_RS16355"
                     /old_locus_tag="OGH68_16355"
     CDS             complement(5216..5428)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OGH68_RS16355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="OGH68_16355"
                     /product="hypothetical protein"
                     /protein_id="WP_264250459.1"
                     /transl_table=11
                     /translation="MSAHGDAGYVVDVRDGRVARVMGRVGTYVQLRPPGGGKEWDCPPG
                     AVRPATPGELLRARVREVNAQARLP"
     gene            complement(5425..5643)
                     /locus_tag="OGH68_RS16360"
                     /old_locus_tag="OGH68_16360"
     CDS             complement(5425..5643)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005315749.1"
                     /locus_tag="OGH68_RS16360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16360"
                     /product="hypothetical protein"
                     /protein_id="WP_264244753.1"
                     /transl_table=11
                     /translation="MTVVRSAERLKAAEEVVDRLRTGLGVVSVTLPSLRVDVVSLASEA
                     PYPLIELGRCNLDTALRLAAVLQGLEK"
     misc_feature    complement(5605..5614)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            5762..6604
                     /locus_tag="OGH68_RS16365"
                     /old_locus_tag="OGH68_16365"
     CDS             5762..6604
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018889536.1"
                     /locus_tag="OGH68_RS16365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16365"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_264244754.1"
                     /transl_table=11
                     /translation="MPGPKDLDPSTSPRALLGAELRHARIKAGLTQDELGEPLFVSGSY
                     IGQMEAGTRRILPEHAARLDEALGTDDFFTRNCEVSNKSRYPDHFAEAAEAEATAETIK
                     EYAPLLVPGLLQTEAYARAVFRAYQPTATDEVIAELVEARLDRAHLLADPTTPLLWAVL
                     DEAVLRREVGGPAVMAGALRHVAGLARRHRIIVQVLPFAAGAHASMNGALRLMSFPDAP
                     PLAYLEVLATGQLEDDPATVARYQLSYDLVRASALSPESSLALIESVAEDYAHEDEQP"
     misc_feature    6263..6265
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6585..6851
                     /locus_tag="OGH68_RS16370"
                     /old_locus_tag="OGH68_16370"
     CDS             6585..6851
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018554875.1"
                     /locus_tag="OGH68_RS16370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16370"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_264244756.1"
                     /transl_table=11
                     /translation="MKTSSHEYDLTTAVWHKSSYSDGSGGNCLEVATWRKSTYSGGEGG
                     NCLEVADGHPDVVPVRDSKNPDGPHLAFPAVAWSAFVADLKQG"
     misc_feature    complement(6970..6983)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.78"
                     /tool="antismash"
     gene            7077..7928
                     /locus_tag="OGH68_RS16375"
                     /old_locus_tag="OGH68_16375"
                     /pseudo=""
     CDS             7077..7928
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018847103.1"
                     /locus_tag="OGH68_RS16375"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16375"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MADCQLSAAPHPLANPGYGKRTVSGQTPLTADDFAHLPKREAAVA
                     AYIDRLADNSDISVKTLAKFTPYGQWAISKALNHLIRAGHLRRGLEAINSESGSTLWVT
                     RT"
     gene            7985..8569
                     /locus_tag="OGH68_RS16380"
                     /old_locus_tag="OGH68_16380"
     CDS             7985..8569
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019762767.1"
                     /locus_tag="OGH68_RS16380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16380"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_264244757.1"
                     /transl_table=11
                     /translation="MTRISAENPEMSVEDFEELARTAPEGVKLEYIAGKLRVKPVPDQL
                     HRAMVMWLLTQCMQQRPDLLLYPEQDLRLEGYRRGRAIADGALAPIDHFVAHEAMWPNP
                     EGVLMTVEVTSHDGDTHNRDRIEKRDGYAAAGIPVYLLIDRDTNSLLVHSEPRNGTYHL
                     ARTYSYGETVRLPSPVDITLETERLKDYTQA"
     gene            8694..9938
                     /locus_tag="OGH68_RS16385"
                     /old_locus_tag="OGH68_16385"
     CDS             8694..9938
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849701.1"
                     /locus_tag="OGH68_RS16385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16385"
                     /product="MFS transporter"
                     /protein_id="WP_264244758.1"
                     /transl_table=11
                     /translation="MLTASSCPPGPNGPLDPRVRRLERRLYAYAGLEDFVLLYPLYALL
                     FAEHGLTTAEISSLFAIWCVVGLLVEVPSGVWADVVSRRAVMVVGPVLTACGFALWALT
                     PSYAAYAAGFTLWAIGGSLRSGSMEALVHDELERLGAADRYGRVMGRAAAVSMAATATA
                     TAAATPALAFGGDTLVWAGSIAACLLCAAVGATLPEHRAAAHPRAKAELPGYVATLRDG
                     LTEVRGSRPVRRAMVLAVVITSVWGVLDEYVPLLAASTGVATETVPLLVLVVWVGVTLG
                     SLLVTAGERLADRTVAALVAAAAAALAAGALSGVPAGFVLLGAAFGTFQLADVLADVRL
                     QSAITGRSRATITSLTGLGTNIVSLLAYGAYAALSPFVSHGAVFALLALPYLLVAAALG
                     RARRPAQAPAGQETQ"
     misc_feature    complement(8720..8734)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 24.27"
                     /tool="antismash"
     gene            complement(10001..10447)
                     /locus_tag="OGH68_RS16390"
                     /old_locus_tag="OGH68_16390"
     CDS             complement(10001..10447)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016638600.1"
                     /locus_tag="OGH68_RS16390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16390"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_264244760.1"
                     /sec_met_domain="PF13471 (E-value: 4e-23, bitscore: 80.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSITVALERNRTRRPLRLRLLTRLAICTARLLVLLRPHLLTRVLT
                     RLSRGAAAANSTQAHGARASVLAASLSLNGLRSCLPRSVSIALLCRLQGVWPTWCVGVR
                     AAPPFAAHAWVEADGELIGERGRPESFARLIAVPPAKAGRATEE"
     gene            complement(10444..10701)
                     /locus_tag="OGH68_RS16395"
                     /old_locus_tag="OGH68_16395"
     CDS             complement(10444..10701)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007460374.1"
                     /locus_tag="OGH68_RS16395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16395"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_264244762.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.9e-21,
                     bitscore: 74.6, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8e-14, bitscore: 50.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLRNRPYLTVTETEYGAVLLDTKTGEYWQMNPSAATAARALLDG
                     GDTDDAVRRVTDHFEVDTERAADDVRALIAAMRSAGVVQE"
     aSDomain        complement(10450..10695)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_OGH68_RS16395_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="7.30E-24"
                     /identifier="RREFam002.1"
                     /label="OGH68_RS16395"
                     /locus_tag="OGH68_RS16395"
                     /protein_end="84"
                     /protein_start="2"
                     /score="74.6"
                     /tool="antismash"
                     /translation="LRNRPYLTVTETEYGAVLLDTKTGEYWQMNPSAATAARALLDGGD
                     TDDAVRRVTDHFEVDTERAADDVRALIAAMRSAGVVQ"
     gene            complement(10729..12540)
                     /locus_tag="OGH68_RS16400"
                     /old_locus_tag="OGH68_16400"
     CDS             complement(10729..12540)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.3"
                     /locus_tag="OGH68_RS16400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16400"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_264244764.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.5e-32, bitscore:
                     112.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSHGAPHFFALPDREDAGAVARRLQAAAPGLRVLHHPSGRPWII
                     GAWADEDIAVARAGTDAVALIGMLPRRTDELPRWTGRLRGRAGRLEALSAAIPGSFHVV
                     GSVGGTLYVQGTAYGMRRVHHTVVNGCPVAGDRAVALAELAGAEIDLTSVALRLPEPLA
                     VQLPPRPMWHGVTDVAPGFALLATGEGTPPRHVRWHTPPAPERSSAEGAADVREALAAA
                     VAVRTQRDGLLSADLSGGMDSTSLCAFAAGQLGAGELIVGGIPGDESISDDAHYARLAA
                     AHWPHVEHVELTPEQTPLFYRGILDDGCRTDIPAGVAMSRDRATAVISLMAERGSRLHM
                     TGHGGDHLFFQTGAYCHDLITRRPLLAWQRVRGYRTLYGWRWRPVLRQLADRRSYRRAV
                     AGIDLSTPGDLGFCTPQLAWIAPPVVQPWLTPECRDLVTAGLREAASQAEPYAPTLGRH
                     RELSALYSGTQECAAIAEAGRRAGVPVTMPYFDDAVVDAALSVRPEDRTDPWQFKPVLK
                     EAVRGVLPEECRARATKFEGTVDAVGGLYRHRDEVRSLWEDSDLAKAGLIDAGALARLT
                     ETPGTPALKDGAVDSTIICEAWLRAVA"
     gene            complement(12563..12679)
                     /locus_tag="OGH68_RS16405"
                     /old_locus_tag="OGH68_16405"
     CDS             complement(12563..12679)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="OGH68_RS16405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16405"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_264244765.1"
                     /transl_table=11
                     /translation="MAKKAAYETPEFVSAGTFRDVTGFVVIFGNDGTGRGWF"
     misc_feature    12880..12895
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            complement(13015..14469)
                     /locus_tag="OGH68_RS16410"
                     /old_locus_tag="OGH68_16410"
     CDS             complement(13015..14469)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1153: Amino acid carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358231.1"
                     /locus_tag="OGH68_RS16410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16410"
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="WP_264244766.1"
                     /transl_table=11
                     /translation="MSTLNTWIVDINDVFWTYLLIPLVAVAGLWFTFRSRAVQLRMIPD
                     MFRVFKDKSTDGVSPFGAFTISAAARIGTGNIAGVATAITMGGPGAVFWMWMMALVGGA
                     SAFVESALAQLYKARGKEPGTYHGGPAYYMERALGKRWLGVLFAVLITLTFGFVLTAVQ
                     SNTITVAVEGSMGGTDSSWFAPVLGVVLAVLLALAVFFGVKRLTAVTKVLIPVMAGIYL
                     LLGLVVVLFNITAVPGMIADIIGGAFGFREVAGGAVGTAILQGVRRGMFSNEAGMGSAP
                     NAAASADTTHPVKQGLVQTLGVYFDTLVVCSMTAFIILSANPTLGERGGADVTQSALNV
                     ALGDWAGHILTLVVFMVAFSSMIGNYYYGESNIRFITGSASAMTGYRAVVLACAVLGAM
                     GSVSVVWSLADITMGAMVLVNLIAILPLSAIAFRLMDDYTAQRRAGLDPVFTRDRIPGL
                     KGVECWEPAGTDADDAQRLAKSHGGQ"
     misc_feature    14431..14445
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    14463..14477
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            complement(14759..16381)
                     /gene="groL"
                     /locus_tag="OGH68_RS16415"
                     /old_locus_tag="OGH68_16415"
     CDS             complement(14759..16381)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /gene="groL"
                     /gene_functions="other (smcogs) SMCOG1299: chaperonin
                     GroEL"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133870.1"
                     /locus_tag="OGH68_RS16415"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES; misfolded
                     proteins enter the barrel where they are refolded when
                     GroES binds; 60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES; misfolded
                     proteins enter the barrel where they are refolded when
                     GroES binds; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16415"
                     /product="chaperonin GroEL"
                     /protein_id="WP_264244767.1"
                     /transl_table=11
                     /translation="MAKIIAFDEEARRGLERGMNQLADAVKVTLGPKGRNVVLEKKWGA
                     PTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLR
                     NVAAGANPMALKRGIERAVEAVSGALLEQAKDVETKEQIASTASISAADVQIGELIAEA
                     MDKVGKEGVITVEESQTFGLELELTEGMRFDKGYISAYFATDMERMEASLDDPYILIVN
                     SKVGNVKDLLPLLEKVMQSGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGD
                     RRKAMLNDIAILTGGTVISEEVGLKLENAGLDLLGRARKVVITKDETTIVDGAGDSDQV
                     QGRVNQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
                     NAKAAVEEGIVAGGGVALLQASSVFEKLELQGDEATGANAVKLALEAPLKQIAVNGGLE
                     GGVIVEKVRNLPVGHGLNAATGEYVDMIAEGIIDPAKVTRSALQNAASIAALFLTTEAV
                     IADKPEKASAAAPGGMPGGDMDF"
     misc_feature    16535..16550
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    complement(16538..16553)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            complement(16801..17004)
                     /locus_tag="OGH68_RS16420"
                     /old_locus_tag="OGH68_16420"
     CDS             complement(16801..17004)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035246.1"
                     /locus_tag="OGH68_RS16420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16420"
                     /product="cold-shock protein"
                     /protein_id="WP_005315736.1"
                     /transl_table=11
                     /translation="MAQGTVKWFNAEKGYGFIAVDGGADVFVHYSAIQMDGYRTLEEGQ
                     RVEFEISQGQKGPQADMVKLAV"
     gene            complement(17415..17690)
                     /locus_tag="OGH68_RS16425"
                     /old_locus_tag="OGH68_16425"
     CDS             complement(17415..17690)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010985363.1"
                     /locus_tag="OGH68_RS16425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16425"
                     /product="MoaD/ThiS family protein"
                     /protein_id="WP_264244768.1"
                     /transl_table=11
                     /translation="MSVNVRIPTILRTYTGGQAEVPAEGATLAEVIADLEKNHTGIAAR
                     VLDDQGKLRRFVNVYVNDDDVRFEQGLETATPEGAGVSIIPAVAGG"
     gene            complement(17728..19047)
                     /gene="thrC"
                     /locus_tag="OGH68_RS16430"
                     /old_locus_tag="OGH68_16430"
     CDS             complement(17728..19047)
                     /EC_number="4.2.3.1"
                     /GO_function="GO:0004795 - threonine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005315732.1"
                     /locus_tag="OGH68_RS16430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16430"
                     /product="threonine synthase"
                     /protein_id="WP_264244770.1"
                     /sec_met_domain="PALP (E-value: 1.3e-61, bitscore: 207.2,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAQTVANTSASTSATASTGSASVDLGPAAALACRECGQRFELGP
                     IFACAECFGPLEVAYDLPSGSPEELRKQIEAGPANIWRYAPLLPVPADVADKPNLNPGW
                     THLVKADNLARELGVTGGLYIKDDSGNPTHSFKDRVVAQALEAARAFGFTTLSCSSTGN
                     LAGAVGAAAARAGFRSCVFIPHDLEQGKVVMAAVYGGELVGIEGNYDDVNRFCSELIGD
                     PLGEGWGFVNVNLRPYYAEGSKTLAYEICEQLGWRLPDQLVVPIASGSQLTKIDKGLQE
                     LIKLGLVEDRPYKIFGAQAEGCSPVSAAFKAGHDVVRPQKPNTIAKSLAIGNPADGPYV
                     LDIARRTGGAVEDVNDEQVVDAIKLLARTEGIFAETAGGVTVGVTKKLIETGVLDPALT
                     TVVLNTGDGLKTLDAVAETSQATAVIRPSLDAFRDAGLAR"
     regulatory      complement(19065..19192)
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(19299..19319)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.9"
                     /tool="antismash"
     misc_feature    19337..19352
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.52"
                     /tool="antismash"
     gene            19375..20343
                     /locus_tag="OGH68_RS16435"
                     /old_locus_tag="OGH68_16435"
     CDS             19375..20343
                     /EC_number="2.4.1.266"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825688.1"
                     /locus_tag="OGH68_RS16435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_16435"
                     /product="glucosyl-3-phosphoglycerate synthase"
                     /protein_id="WP_264244772.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.5e-07,
                     bitscore: 30.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDEVARWLSRRSWSASDRSLDRLISAKVRQGTTVSAVLPALNEE
                     ATVGDIVTIIRRELMENVPLVDELVVIDSASSDRTSEVAAAAGARVVHRDSILPGLPAV
                     AGKGEVLWRSLMVTGGDIVCFCDSDLRDFSPDFVSGIVGPLLTEPEVQFVKAMYDRPLG
                     GGAAPGPDGVPAQGGRVTELVARPLLNLHWPQLAGFVQPLGGEYAARRSLLERLPFPVG
                     YGVELGLLIDSLNLVGLDALAQVDVGTRKHRHQDGQALGRMAATIYRTAQLRLSRPHLV
                     RPSITQFDRVGNGFAPRTYRVDTEERPPMLEIGEYAARRAA"
     misc_feature    complement(20346..20361)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.43"
                     /tool="antismash"
     misc_feature    20360..20374
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.09"
                     /tool="antismash"
     gene            20382..20669
                     /locus_tag="OGH68_RS16440"
                     /old_locus_tag="OGH68_16440"
     CDS             20382..20669
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OGH68_RS16440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="OGH68_16440"
                     /product="hypothetical protein"
                     /protein_id="WP_264244774.1"
                     /transl_table=11
                     /translation="MAFIGFLAPPRGRHRRPTPSGAHERLTRLLGVLAVTTAATLGPAG
                     PATASQQVEMARTGTTAEQLWLLGGITLSLTAAGLVALAATRHRRDRRDP"
     misc_feature    complement(21731..21744)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
ORIGIN
        1 gctggagcaa cgccgcgatg accggctccg tcgaggcccg ggcgttcgtc gacgtctcgc
       61 gccgcgccca gctcgaccac ctggaacggt ccctcgtccg ccaccaggag gacctggcgg
      121 ccggccgcct cggtgacgaa tggctggagc cctccggctt caccgacctg gtggcacggc
      181 tgacccccga ggccgtcacg gagctgtggg agaccttcaa ccgcgccgtg gccgagctcg
      241 ccgcccgcga cgagggcgac ccgcgcgccg agcaggtcgt gctcttcgcc gccggcctcg
      301 cggtccacgt ggagagccgc gcgggaaaac agacgggaaa ccaggcggag gaccgggcgg
      361 gaaaccagac gcacgcgcag gcggaggacc gggcggagga ccgctcgtga accggccgct
      421 ggacccgcgt gcggcccgcc gccgcttcgt cgccgtcacg ttcctcttct ggctgcccgt
      481 cgggctctac atcccgtccc aggtgctgct gctgaccgaa cgcggtatga gcctcgccgt
      541 cgtcgccggg ctcttcgccg tccactcggt gaccgtgtcc gtcctggagc tgccgaccgg
      601 cggcctgtcc gacgtcgtcg gccgccgcgc cgtgctggcc gccgcgggcc tgctcaacct
      661 ctccgcgctg accgtgatgg cgctcggcac caccgtctgg gccctggccg tcgccatgtt
      721 cctgatgggc tccggccgcg cgctgtccag cggcccggcg gaggcctggt acgtcgacac
      781 cgtccaggcc cactccggtc ccggcgccga actgcgcacc ggcctggccc gcggcaacac
      841 cgcgtccgcc gccgcgctcg ccgcgggcac gctcctcggc ggcgccctgc cgctcctgct
      901 gggcctcggc acggaccccg gcgcccggct ggccgacgcc accggcggcc tcgtactgcc
      961 gctgtcggtc cccggcctgc tcggcgcggc cgtcggcgtc ggctatgtcg cgtacgtgct
     1021 gaccgccctg cccgagccgc cccggccgcc cgccacgctg cgcggggtgc tgcgcggtgt
     1081 cccggcgacg atgctgggcg ggctgcggct cggcgtcacc gagccgctgg tccgccgggt
     1141 cctgctgacg gcggccgccg ccggcgcggc gctcgccacc gtcgagctcc tcaccccggg
     1201 ccgggccgcc cggctcaccg gcgcaccgga gtccggcgcc gtgctgtacg cctccctcgc
     1261 ctgcgccggt ttcctgtgca cggcggtcgg cagccactgc gcgccgccgg cggcccggct
     1321 gacgggcagc ggcgaacacg cggtgctggc cgccctcggc gtgagcacaa cggggctcgc
     1381 gctgctcggc gtgacggccg cctgggacgg cggcaccgcc ccgctggtcc ttgccgccgt
     1441 cggctacggc ctggtctacc tcggcctggg cgccgccggc ccgaacgaga acgacctgct
     1501 gcaccgccgc gtcgacagca cggtccgcgc gacggccctg tcggtgaagt cgctcgccct
     1561 ccagtcggtc gccgcgctga ccggcctcgt cgccggctcc ctcccgatcg gcccgctgcc
     1621 gtggctggtg ggtgccaccg ccctgctgct gggcgcgctc ctgtggatcc gccgggcgaa
     1681 gccggtcccg gctgccgctc cggccgtgtc cgggctcacc gcgacagagt cggtgcccgg
     1741 gcgttgaatg ggaagcatgg ttctccagcg acctgtgggc caccgccgac gcagggctcc
     1801 cggggcggtg ctcctggcct ccctcctcgt ggcgaccggc gccaccgcgg caggcgcggc
     1861 ggaacccccg ccgccgcccc cgccccagct gaccgacaag caggtcgacg acgcggtggc
     1921 caagctcgac ggcatcgtcc gcgacggcat gaagaggacg ggcgtaccgg gcgtcgccgt
     1981 cgccgtcgtc cacaaggacc gggtcgtgca catcgagggg ttcggggagc gggagaccgg
     2041 caaggccggt gccgtgtcac cggacacggt gttccaactg gcctccctgt ccaagccgct
     2101 ggcctcgacc gtggtcgccg gcgccgtggg cgacaaggcg atcgcctggg acgaccccgt
     2161 ggcgaagcac gtcccgcact tcgcgctgaa ggacccgtgg gtgacggagc acgtcaccgt
     2221 cgccgacctc ttctcgcacc gcagcggcct gcccgaccac ggcggtgacc tgctggagga
     2281 cctcggttac gaccgcgact acatcctgtc ccacctgcgc cacctgcccc tggccccgtt
     2341 ccgcgcctcg tacgcgtaca ccaacttcgg tctcaccgcg gccggtgtgg ccgtggccga
     2401 ggcgagcaac accgactggg agaagctggc ggaggacacg ctgtactcgc cggccggcat
     2461 gaactccacc agctcccgtt tcgacgacta cgagaaggcg cgcaacaagg cggtcacgca
     2521 cgtcaaggag ggcgacacct ggaaggccag gtacgtacgg gacgccgacg cccagtcccc
     2581 cgcgggcggt gtcagctcca ccgccgagga catggccacc tggatgcgcc tgcaactcgc
     2641 caacggcaag ctcggcgacg accggatcat ccccgccggc ccgctcaccc gcacccacga
     2701 gcccgccgcc gtcgcccagc cccccgccgc cccgacggac cgcaccggct tctacggcct
     2761 cggctggaac gtcggctacg acgatcaggg ccggctccgc ctcagccact ccggcgcgtt
     2821 cggcctcggc gccaacacca acgtcaccct gctgcccgcc gaacagctcg gcatcgtggt
     2881 cctcaccaac ggtgaaccgg tgggcctcgc ggactccgtc gcattcaact tctacgacac
     2941 ggcccagtac gggaagccga ccggcgactg gctcgccagg atcggccagg tctaccagca
     3001 ggaggagcag gaggcccgct cccccaccga ctacggcagg ccgccgcccg acgccgccga
     3061 cgcacagccc gacaacacgt acacgggcac gtaccgcaac gactactacg gcaccctcag
     3121 ggtcaccgcc tcgaacggcg agctgaccat ggaactcggc ccgaaacccc tgcggttccc
     3181 cctcgcccac tacgacggca acaccttcag cttcatgaca gtgggcgaga acgcggtcgg
     3241 ccgctccggg gtcatgttca ccgtcgactc ggacgccaag gcgtcgaagg tccgcgtcga
     3301 gagcctcgac aagaacggcc tcggcacctt cacccgccag tagggcggcc cgagcatcgg
     3361 cgccttcact cgggtcgtcc ggagccctcc gatcacaacc gcgtgccggg cacccgagag
     3421 gcggggcggc gcggagctcg gccttgcatc catgtacatg gaggggcaca ctgaggcaca
     3481 gattatgtac aggatggagt ccacatggct ctgacccaca tcgacatcga cgacgaggcc
     3541 ctggagaccg ccaagcgtct gggaggccac cgcaccaaga ccgctgccgt cgcgaaggcg
     3601 ctggaggagt acaacaagcg cctgttgcgc gccgccgcgt acaagaagta tttcgagatc
     3661 gcccaggact gggacatcga ggccgccgaa gccgcccaca aggccgacaa ggagaccttc
     3721 ggccggtgaa cgtctatctg ctcgactcgt cagccctgtg gcgcatgctg cgcgaaaggt
     3781 ccctgcacac gacatggcag gacactgtcc tggagggcga cgttcgttcc tgctatccgc
     3841 agcgcgtgga gttcctgcgc tcggcgcggg acgcgaagga gtacgaggcg tacagcgcga
     3901 tgttcgccga actgtacgac gacgtccccg tgccgaagag cgccgcgcac tgggtcgggg
     3961 gcctccagac acgagccgcc ccgcacggag cgcaccacgc gctctcggcg gtcgatctcc
     4021 agatctgctc gactgctgcc caccacggat tgatcgtcct gcacgacgac cgggacttcg
     4081 tgaccgcagc acgtttcgcg gtcgagttgc agcagcacaa cgtgcacgac ggcccgcgct
     4141 gagcggctca cccgcgcagc gtcaccccgt accgcgtccg gaggcgggtg agctcccacc
     4201 acgcgatggc cgtcaccgac gccgggccgc cgatgaccgc gcagatctgg acggccggcg
     4261 ggcccggcgg catgcccgcc gtggtcaggt tgacgaccgc cagctcccac accaggacgc
     4321 cggtgagcag agccggaagc gccgcgtgca cctcggccgt gctgaacgcg gtacggacgg
     4381 cggttgtgga ggcgaagacg acgaagaaca gcacccacag caccggaagc agcagcgcga
     4441 gcgtgaccag cgggctgagg gggctgctcg cgtagctctc gctgagcagc atcacgcccg
     4501 cgaacagcag cggcacggcc gtgaaggcgc cgaagtacca gagcaccgag cggaccgcgg
     4561 gccgcaggcg ggcccgcatg cccggccgcg cggcgggcgg cgcgagccgg aacaggacga
     4621 gcagcacgaa cggggtggtg aggagcagca gccacggggt gatcgcgagc cggaagaagt
     4681 actgctcctg cacctcgttc cagtccgcct ccgtgccgta ggcgaccagg atcaggaacg
     4741 acgcgcccag cgcgccccac gcccgggctt tctgcacgcg ccacacctcg gggtcgtgat
     4801 agcggcggat gctgtgcgcg gggaacttcc gccgggcctg ccgacgggcg gaccgggcca
     4861 gcggatagcc gatcagcaca gccagcgcgg gccacacgca gcacataccg agcgccagaa
     4921 ggcaccccgg cacccgccgc agctcatgga gcagctctcg cagcgggggc cactcgtcct
     4981 cgcggaaccg ctgccacagc gtcgggcgcg gcccgtacgg ccggtacggt aacggcggcc
     5041 ccggatacgg ccccggctgc ggcggtacgc ccggccgagg cggcggccct ggctgcggct
     5101 gcccggtccg ccggtacgga ttctgtcccc cgaacgtcac gcctgcgtcc ctcctggagt
     5161 ggtcggacga tcattccagg aaggcgaact gccgtgcagc acagcccaca tggcgtcacg
     5221 gcagccgcgc ctgcgcgttc acctcccgca ctcgggcccg cagcagctcg cccggcgtcg
     5281 ccggccgcac ggccccgggc gggcagtccc actccttgcc cccacccggc ggccgcagct
     5341 gtacgtacgt accgacccgg cccatcaccc gcgccacccg cccgtcccgg acgtcgacga
     5401 cgtacccggc atcgccgtgc gcgctcactt ctccagccct tgcagcacgg ccgccagccg
     5461 cagcgccgtg tccaggttgc agcgccccag ttcgatcagc ggatacggcg cctcgctagc
     5521 cagcgacacc acatcgaccc gcagcgacgg caacgtcacc gacaccaccc ccagccccgt
     5581 cctgagccgg tccaccacct cctcggccgc cttcaaccgc tcggccgatc gcaccaccgt
     5641 catgttctcc gcacctccag tacgcagtgt tccgattcat cacccagcgt gtacggatgc
     5701 tggctagcct gggaagagac ggcggcccaa caacgcgacc tgtcgatcag ggagttgcac
     5761 catgcccgga cccaaggacc tcgacccgtc gacctcacca cgcgcactgc tcggcgcgga
     5821 gctgcgccac gcccgtataa aggccggtct cacacaggac gagctgggcg aacccctgtt
     5881 cgtcagcggt tcgtacatcg gccagatgga agccggcacc cgccgcatcc tccccgagca
     5941 cgcggcccgc ctcgacgagg ccctgggcac ggacgacttc ttcacccgca actgcgaggt
     6001 gtccaacaag tcccgctacc cggaccactt cgccgaggcg gcggaggcgg aagcgacggc
     6061 ggagaccatc aaggagtacg cgccgctgct cgtccccggc ctgctccaga cggaggcgta
     6121 cgcacgagcg gtgttccgtg cctaccagcc gacggcgacg gacgaggtca tcgccgaact
     6181 cgtggaggcg aggctcgacc gcgcccacct gctggccgat ccaacaacgc cgttgttgtg
     6241 ggccgtgctc gacgaggccg tgttacggag ggaggtgggc ggcccggcgg tgatggccgg
     6301 ggcactgcgc catgtggcag gcctggcgcg gcggcaccgg atcatcgtgc aggtcctgcc
     6361 gttcgcggcg ggcgcgcacg cgtcgatgaa cggcgctctc agactgatgt ccttcccgga
     6421 cgcacccccg ctcgcctacc tcgaagtcct tgcaacgggc cagttggagg acgatccggc
     6481 cacggtcgcc cgataccaac tgtcctacga tctggtcagg gccagcgcac tgtcgccgga
     6541 atcgtccttg gccctgatcg agtcagtggc ggaggattac gcgcatgaag acgagcagcc
     6601 atgagtacga cctgaccacg gccgtctggc acaagtccag ctacagcgac ggcagcggcg
     6661 gcaactgcct ggaggtcgcc acctggcgca agtcgaccta cagcggtggc gagggcggca
     6721 actgcctcga agtcgcggac ggccaccccg acgtcgtccc cgtccgtgac tccaagaacc
     6781 ccgacggccc ccatctcgcc ttcccggccg tcgcctggtc ggccttcgtc gccgacctca
     6841 agcagggctg aggcagcagt cccggagctc aagtcccgag attcgagcgc tcttcacagt
     6901 gatgtggggg gtgggtcctg ttgaacccac ccaccctccc tgtcgagttg acatcacgcg
     6961 accgacttgc cacgcagcgt catcacgctc cagcgttccg ataaacgaac aacccccgcc
     7021 aggtgctacc aacacctgcg ggggtctgac catcacgatc gaaagagcct cgatccatgg
     7081 ctgactgcca gcttagtgct gccccgcatc ccctcgccaa ccccggctac ggcaaacgaa
     7141 ccgtgtcggg ccaaacgccg ctcaccgctg acgacttcgc acatctgccc aagcgtgagg
     7201 cggccgtcgc cgcgtacatc gaccggctgg ccgacaacag cgacatctcc gtgaagacgc
     7261 tggccaagtt caccccgtac ggccagtggg ccatctccaa ggcgctcaac cacctgatcc
     7321 gggccggtca tctgcggcgc gggctcgaag cgatcaactc cgagtcgggc agcaccctgt
     7381 gggtaacacg cacatgatgg tcccgtacgg cacacgacga cgcgtggtgg gcggccttcc
     7441 agcgcggtga cgtgccggtg gaaccggtgg agaagcgccg accgacccgc tcgcgggcgt
     7501 acgtcctgct cgccgcgctg gggcgggcga acccgatgat gtcgctgtcc cacaccgagt
     7561 gcctggcgct cgtgccgctg gtggacgagt ggttcgcgcg cgtcgcgacc gagcggcagc
     7621 tgctgcacgc gctcaccgac gggctgcccg tcccggtcca ccacgccgcc gcgctcgccc
     7681 gccgccgcct caccgacaag ctcccgtcgg agccggtccc gctgccgccg ccccaccgca
     7741 tcctcgaatg cggcaagtgc ggggcgcccg gccgggcgga cgcgctcgtg gacggcgtat
     7801 gcgcccgctg ccgaggcggc gacacggccc cgccacccac tctcccggcg gcccgcgtcc
     7861 acgcccacgc ggcccaggcc cgcgcggcgg cgacccgccc gcccgagacg acaaggacac
     7921 agccatgacc gtgccgctca cccggccccg ccacggggga cgatggaggg gaggaggcga
     7981 cgccatgacc cgcatcagcg ccgagaaccc cgagatgtcc gtcgaggact tcgaggaact
     8041 ggcacgcact gcccctgagg gcgtaaagct cgagtacatc gcaggaaagt tgagggtcaa
     8101 gcccgtgccg gaccagcttc acagggcaat ggtcatgtgg ctactgacac agtgcatgca
     8161 gcaacggcct gacctgcttc tttaccccga acaggacctg cggctggagg gctaccgccg
     8221 ggggcgcgcc atcgcggacg gcgcgctggc tccgatcgac cactttgtgg cgcatgaggc
     8281 catgtggccg aacccggagg gcgtcctcat gaccgtcgag gtcacctcac acgacggcga
     8341 cacccacaat cgcgaccgga tcgagaagcg cgacggctac gcggccgccg ggattcccgt
     8401 ctatctcctc atcgatcggg acacaaactc gcttctcgtt cacagcgagc ccaggaacgg
     8461 cacgtaccac ctcgcccgga cctactccta cggcgagacc gtccggctcc cctctcccgt
     8521 cgacatcacc ctcgaaacgg agaggctcaa ggactacacc caggcgtaaa ctcggccgca
     8581 tgagccgacg acgacattga tccaccgcct ctggtccagg aacgggctgt cgcgggccgc
     8641 cgcgcgggtg agcacccggc gtcccctgtc cgtcccagcc aaggaccaca cgcatgctca
     8701 ccgcttcgtc gtgcccaccc gggccgaacg gcccgctcga tccccgcgtc cgcagacttg
     8761 agcgacggct ctacgcctac gcgggacttg aggacttcgt cctcctctac cccctctacg
     8821 ccctgctctt cgccgagcac ggtctgacca ccgccgagat ctcgtccctg ttcgccatct
     8881 ggtgcgtcgt cggcctgctg gtcgaggtgc cgtccggtgt gtgggccgac gtcgtgtccc
     8941 gccgggccgt gatggtcgtc ggcccggtgc tgaccgcctg cgggttcgcg ctgtgggcgc
     9001 tgaccccgtc gtacgccgcc tacgccgccg ggttcacgct ctgggcgatc ggcggttcac
     9061 tgcgctcggg ctcgatggag gccctcgtcc acgacgagct ggaacggctc ggcgcggccg
     9121 accgctacgg gcgggtcatg ggccgggcgg cggccgtcag catggccgcg accgccacgg
     9181 cgaccgccgc cgccacgccc gcgctcgcct tcggcggcga caccctggtg tgggcgggca
     9241 gcatcgccgc gtgcctgctg tgcgcggcgg tcggcgcgac gctccccgag caccgggcag
     9301 ccgcccaccc tcgcgcgaag gccgaactcc cggggtacgt cgccaccttg cgggacggcc
     9361 tcaccgaggt acgtggcagc cggcccgtcc gccgggccat ggtgctcgcc gtggtgatca
     9421 cctcggtgtg gggcgtgctg gacgagtacg tgccgctgct ggccgcgtcc acgggcgtgg
     9481 cgaccgagac cgtaccgctg ctggtgctgg tggtgtgggt cggtgtgacg ctcggctcgc
     9541 tgctggtcac ggccggcgaa cggctcgcgg accgtacggt ggccgcgctg gtcgcggcag
     9601 ccgccgccgc actggccgcg ggcgcgctct ccggcgtgcc tgccggattc gtgctgctcg
     9661 gtgccgcgtt cggcaccttc cagctcgcgg acgtcctggc ggacgtacgg ctccagtcgg
     9721 cgatcaccgg ccgaagccgg gcgacgatca cctcgctgac cggtctgggc accaacatcg
     9781 tctccctgct ggcgtacggc gcctacgcgg cgctgtcccc gttcgtctcg cacggtgccg
     9841 tcttcgccct gctggcgctg ccgtacctgc tggtggccgc cgcgctgggc cgggcgcggc
     9901 gaccggccca ggcgccggcc ggtcaggaga cgcagtagcg gtccccctcg ggccggcctt
     9961 cggaccgccc ttcaggccgg tcttctgccc tgagctctcg tcactcctcg gtggcgcgcc
    10021 ccgccttggc cggcggcacg gcgatcaggc gggcgaagct ctccgggcga ccccgttcgc
    10081 cgatcagttc accgtccgcc tcgacccatg cgtgcgcggc gaacggcggt gccgcccgta
    10141 cgccgacgca ccaggtgggc cacacgccct ggagacggca gagcagcgcg atggagaccg
    10201 agcgcggcag gcacgaacgc aggccgttga ggctgaggct ggccgccagc accgaggccc
    10261 gggcgccgtg cgcctgggtg ctgttcgcgg cggcggcccc ccggctgagg cgggtcagta
    10321 cgcgggtcag cagatgaggt ctgaggagaa ccagcagccg ggcggtgcag atggccagcc
    10381 gggtgaggag ccgcagccgc agcggccgtc tggtccggtt gcgctccagg gcgacggtga
    10441 tgctcactcc tgcaccaccc cggcggagcg catggccgcg atcagggccc gcacgtcgtc
    10501 cgccgcgcgc tccgtgtcca cctcgaagtg gtcggtgacg cgccggacgg cgtcatcggt
    10561 gtcgccgccg tccagcagcg cccgggcggc ggtggcggcg ctggggttca tctgccagta
    10621 ctcgccggtc ttggtgtcca gcaggaccgc accgtattcg gtctcggtga cggtcagata
    10681 cgggcggttg cgcagcttca tcgcattcct tccttccggc cgggcacgtc aggcgactgc
    10741 gcgcagccat gcttcgcaga tgatggtgga gtccacggcg ccgtccttga gggcgggcgt
    10801 gccgggtgtc tccgtcagcc gggcgagcgc gccggcgtcg atgagcccgg ccttggccag
    10861 gtcgctgtcc tcccacagcg accggacctc gtcgcggtgc cggtagagac cgccgaccgc
    10921 gtcgacggtg ccttcgaact tggtggcgcg tgcccggcac tcctcgggca gcacgccgcg
    10981 taccgcttcc ttgagcacgg gcttgaactg ccaggggtcg gtccggtcct cggggcgtac
    11041 cgacagtgcg gcgtcgacca ccgcgtcgtc gaagtacggc atggtgacgg gaacgcccgc
    11101 ccggcgtccg gcctcggcga tcgccgcgca ctcctgcgta ccggagtaga gggccgacag
    11161 ctcccggtgg cggccgagcg tgggtgcgta cggctcggcc tgcgaggcgg cctcccgcag
    11221 cccggcggtc accaggtccc ggcattcggg ggtgagccac ggctggacca cgggcggggc
    11281 gatccaggcc agttgcgggg tgcagaagcc gaggtcgccg ggtgtgctca ggtcgatccc
    11341 ggcgaccgcg cggcggtagg agcgccggtc ggcgagctgg cgcagcacgg ggcgccagcg
    11401 ccatccgtag agggtgcggt agccgcggac ccgctgccag gccagcagcg ggcggcgggt
    11461 gatcaggtcg tggcagtagg cgccggtctg gaagaacaga tggtcgccgc cgtgtccggt
    11521 catgtgcagc cgggagccgc gctccgccat cagggagatc acggcggtgg cgcggtcgcg
    11581 gctcatggcg acaccggcgg ggatgtcggt gcggcagccg tcgtcgagga tgccgcggta
    11641 gaacagcggg gtctgctccg gcgtcagttc cacgtgctcg acgtgcggcc agtgcgcggc
    11701 ggcgagacgg gcgtagtggg cgtcgtcgct gatcgactcg tccccgggga tgccgccgac
    11761 gatcagttcg cccgcgccga gttgtccggc ggcgaaggcg cacagcgagg tggagtccat
    11821 cccgccggac aggtccgcgc tcagcaggcc gtcccgctgt gtgcggacgg cgacggcggc
    11881 ggccagcgcc tcgcgtacgt cggccgcgcc ttcggccgac gagcgctcgg gggcgggcgg
    11941 ggtgtgccag cggacgtgcc ggggcggggt gccttcgccg gtggcgagta gggcgaatcc
    12001 gggggcgacg tcggtcacgc cgtgccacat ggggcgcggg ggcagctgca cggccagtgg
    12061 ttcgggcagc cgcagggcca cggaggtgag gtcgatctcg gcgccggcca gctccgccag
    12121 cgccacggca cggtcgccgg ccaccgggca gccgttcacg acggtgtggt gcacgcggcg
    12181 catgccgtag gccgtgccct gcacgtacag ggtgccgccg acgctgccca ccacgtggaa
    12241 gctgccgggg atcgccgcgg aaagggcctc gagccgtccg gccctgcccc gcagccttcc
    12301 ggtccaccgg ggcagttcgt cggtccgtcg cggcagcatg ccgatcagcg cgacggcgtc
    12361 cgtgccggcc cgggcgacgg cgatgtcctc gtcggcccag gcgccgatga tccaggggcg
    12421 gccggaggga tggtgcagca cccgcagtcc gggtgccgcg gcctggaggc gacgggccac
    12481 ggcgcccgcg tcctcgcggt caggaagcgc aaagaagtgc ggtgcgccgt ggctcgtcat
    12541 cacgggttcc tccgggagtc cgtcagaacc agccgcgtcc ggtgccgtcg ttgccgaaga
    12601 tcaccacgaa gccggtgaca tcgcggaagg tgccggcgga aacgaactcc ggggtctcgt
    12661 aagcagcctt cttcgccatc gttcaggtcc tttctcttga tgggatcgga atggatccgt
    12721 agggatctgg ggggtgaccc gcatggatcc gttggatcga tcgaacgatc ggcagaagcc
    12781 ttgccgccct gggcgtggcc gggcgagggc gctgaccgct tggtgccggt cccgggaacg
    12841 tgcttggcag gtccggccgg accacgcatg accggccggg gtgaaccacg tcacatcggc
    12901 cgccccggtg ccgcctgtcc gggcccggaa acgcccgagg gcggcacccc cttgaagggg
    12961 tgccgccctc ggccctgcgg tcgggtccgg tccgggaggg accagaggtc cgtgtcactg
    13021 cccgccgtgc gacttggcga gccgctgcgc gtcgtcggcg tccgtgcccg ccggttccca
    13081 gcactccacg cccttcaggc cggggatgcg gtcccgggtg aagacggggt ccagtccggc
    13141 acggcgctgg gcggtgtagt cgtccatcag ccggaaggcg atcgccgaca gcggcaggat
    13201 cgcgatcagg ttgacgagga ccatcgcgcc catcgtgatg tccgcgaggc tccacacgac
    13261 gctgaccgag cccatcgctc cgagcacggc acaggcgagg acgaccgccc ggtagccggt
    13321 catcgccgac gcgctgccgg tgatgaagcg gatgttggac tcgccgtagt agtagttacc
    13381 gatcatggag ctgaaggcga ccatgaagac gaccagcgtc aggatgtgtc cggcccagtc
    13441 gccgagggcc acgttgaggg cggactgggt gacgtccgcg ccgccgcgct cgcccagggt
    13501 cgggttggcg ctgaggatga tgaacgcggt catgctgcag acgaccagcg tgtcgaagta
    13561 gacgccgagg gtctgcacca ggccctgctt gaccgggtgc gtggtgtccg cggaagcggc
    13621 ggcgttgggc gcggagccca tgccggcctc gttggagaac atgccgcgcc gcacgccctg
    13681 gaggatcgcc gtgccgaccg cgccgcccgc gacctcgcgg aagccgaacg cgccgccgat
    13741 gatgtcggcg atcatgccgg gcaccgcggt gatgttgaac aggacgacca cgaggccgag
    13801 cagcaggtag atgcccgcca tcaccgggat cagcaccttg gtgaccgcgg tgaggcgctt
    13861 cacgccgaag aacacggcca gcgcgagcag cacggccagc acgacgccga gcaccggggc
    13921 gaaccagctg gagtccgtac cgcccatgga gccctcgacg gccaccgtga tggtgttgga
    13981 ctgcactgcg gtgagaacga acccgaaggt cagagtgatg agcacggcga acagcacacc
    14041 gagccagcgc tttccgaggg cgcgctccat gtagtaggcc gggcctccgt ggtacgtgcc
    14101 gggctccttg ccgcgcgcct tgtacagctg ggcgagggcg gactcgacga acgccgaggc
    14161 gccgccgacg agggccatca tccacatcca gaagaccgcg ccgggcccgc ccatggtgat
    14221 ggcggtggcc acaccggcga tgttgccggt gccgatgcgg gcggccgccg agatggtgaa
    14281 ggccccgaag ggggagacgc cgtccgtcga cttgtccttg aagacccgga acatgtccgg
    14341 gatcatccgc agctggaccg ccctggagcg gaaggtgaac cagaggccgg ccacggccac
    14401 cagcgggatc agcagatagg tccagaagac atcattgatg tcgacgatcc aggtgttgag
    14461 ggtgctcatg atgagatgcg tcccgggtct ttgtgagtcg gggctcggct cgggctgcga
    14521 tgcgtacggg tcgcgtacag ctggtgccct cggccgcgga agcattcttc cgttcaaagc
    14581 tctgcagagc taaccagggc cttgtcccgc tgaaaagaca ttccggtcgt gcggcatctc
    14641 acactctgta ccggtttctc ccgcagaaaa ccgccctgga gcggcaacgc ccgagggcgg
    14701 caccccctgg gagtggggtg ccgccctcgg tcaaggacgg ttgatcgaca gaagtcgatc
    14761 agaagtccat gtcaccgccc ggcatgccgc ccggagcggc cgcggaggcc ttctccggct
    14821 tgtcggcgat gacggcctcg gtggtgagga acagcgccgc gatggaggcc gcgttctgca
    14881 gagcggaacg ggtgaccttc gcggggtcga tgatgccctc ggcgatcatg tcgacgtact
    14941 caccggtcgc ggcgttcagg ccgtggccga cgggcaggtt gcgcaccttc tcgacgatga
    15001 cgccaccctc gagaccaccg ttgacggcga tctgcttgag cggggcctcc agcgcgagct
    15061 tcacggcgtt ggcgccggtc gcctcgtcac cctggagctc gagcttctcg aagaccgagg
    15121 aagcctgcag cagcgccacg ccaccaccgg cgacgatgcc ctcctcgacg gccgccttcg
    15181 cgttgcgaac ggcgtcctcg atgcggtgct tgcgctcctt gagctcgacc tcggtcgcgg
    15241 caccggcctt gatgacggcc acgccgccgg ccagcttcgc cagacgctcc tggagcttct
    15301 cgcggtcgta gtccgagtcg ctgttctcaa tctcggcacg gatctggttg acgcgaccct
    15361 ggacctggtc gctgtcaccg gcaccgtcga cgatcgtggt ctcgtccttg gtgatgacga
    15421 ccttgcgggc gcggcccagc aggtccaggc cggcgttctc gagcttgaga ccgacctcct
    15481 cggagatgac cgtgccgccc gtgaggatgg cgatgtcgtt cagcatggcc ttgcggcggt
    15541 cgccgaagcc cggggccttg accgcgacgg acttgaaggt gccgcggatc ttgttgacga
    15601 ccagggtcga cagggcctcg ccctcgacgt cctcggcgat gatcagcagc ggcttgcccg
    15661 actgcatgac cttctccagc agcggaagga ggtccttcac gttgccgacc ttggagttga
    15721 cgatcaggat gtacgggtcg tccagggacg cctccatacg ctccatgtcg gtggcgaagt
    15781 acgccgagat gtagcccttg tcgaagcgca tgccctcggt gagctcgagc tccagaccga
    15841 aggtctggga ctcctcgacg gtgatgacgc cttccttgcc gaccttgtcc atggcctcgg
    15901 cgatgagctc gccgatctgg acgtcggcgg cggagatgga ggcggtggag gcgatctgct
    15961 ccttggtctc cacgtccttg gcctgctcga gcagggcacc ggagacggcc tcgacggccc
    16021 gctcgatacc gcgcttcaga gccatcgggt tggcgccggc ggccacgttg cgcaggccct
    16081 cacggacgag cgcctgggcg aggacggtcg ccgtggtcgt accgtcaccg gcgacgtcgt
    16141 ccgtcttctt ggcgacttcc ttgaccagct cggcgccgat cttctcgtac gggtcctcga
    16201 gctcgatctc cttggcgatg gaaacaccat cgttggtgat cgtgggggcg ccccacttct
    16261 tctcgaggac gacgttgcga cccttggggc caagggtgac cttgacggcg tcggcgagct
    16321 ggttcatccc gcgctcgaga ccgcgccgtg cctcctcgtc gaacgcgatg atcttggcca
    16381 tgtgaagtgg tcctcccgga ctggggtgga ttgcttcgga tcgcatccgg cgcccgcgac
    16441 ggacggcctg cgcgccgcgt ggttccttgc cccacccggc ccgcgggcct caccgacccg
    16501 atccaagttc tgtcactctc actgggagag tgctaacgcc aatgattagc actcgacccc
    16561 cgagagtgca agcggctccg aagaagcctc cctgaggagt ggcggtcggg tgacgggagg
    16621 gcgcaagcgg cttcgaggga acgcgaggcg gcgcctggga ggcggccgac gccggatcgc
    16681 gccgggaggc gaccggagag acggacgggc gcgcccgggc acgcgtgagg ggcccgcatc
    16741 ccggtgaccg ggaggcgagc ccctcatgcg tgagtgcgtc ggtggccgat cgcgcctgga
    16801 tcagacggcg agcttgacca tgtccgcctg cggacccttc tggccctgcg agatctcgaa
    16861 ttcgactcgc tgaccttctt caagggtgcg gtaaccgtcc atctggatcg cgctgtagtg
    16921 gacgaaaaca tccgcaccac cgtcgaccgc gatgaagccg taccccttct ccgcgttgaa
    16981 ccacttgacg gtgccctgag ccatgcctaa ctcccctatt actggccctt gcgcaggacc
    17041 gcacttcgcg gacccgggtc agatctccac cccagcagga ggggtgtgcg ccggaacgcg
    17101 tcgaccgcgg ctgaatgtat ctgcccaact gccctctgca acaggtcaat cggacgagaa
    17161 ttctgggcag gaccgaacga ccgatcccta cgattccata gaattccggg gcaagtcggg
    17221 cccggcaaat gacgcctaag tggcaattcg atcacgcagt ttggccgcat tcttgcggaa
    17281 ctcgaaggca ttcacgagcg gccggcggag ggggcttccc agactctacc gcgctcaacc
    17341 atgcagaatt gccccctccg cttctcggcg gagagggcaa tctctgtaac tacgagtaaa
    17401 tctttggggt tggatcagcc gccggcgacc gcgggaatga tcgacacgcc cgcgccctcc
    17461 ggcgtggccg tctccaggcc ctgctcgaac cgcacgtcgt cgtcgttgac gtacacgttg
    17521 acgaaccggc gcagcttgcc ctggtcgtcc agaacgcggg ccgcgatacc ggtgtggttc
    17581 ttctcgaggt ccgcgatgac ctcggcgagg gtcgcgccct ccgccgggac ctcggcctgg
    17641 ccgcccgtgt acgtacggag gatggtgggg atgcggacgt tgacgctcat gtgtgcagcc
    17701 ttccttgggt ctcggatctc agggatctca acgggccagg ccggcgtcgc ggaacgcgtc
    17761 caggctcggg cggatgacgg cggtcgcctg tgaggtctcc gcgaccgcgt cgagggtctt
    17821 gaggccgtcg ccggtgttga ggacgacggt ggtgagcgcc gggtcgagca cgcccgtctc
    17881 gatgagcttc ttcgtcacac ccaccgtcac accgcccgcc gtctcggcga agatgccctc
    17941 ggtacgggcc agcagcttga tcgcgtcgac gacctgctcg tcgttcacgt cctccaccgc
    18001 gccgccggtg cggcgggcga tgtccagcac gtacgggccg tcggccgggt tgccgatggc
    18061 cagcgatttg gcgatggtgt tcggcttctg cgggcgcacg acgtcatgac cggccttgaa
    18121 cgcggcagag accggcgagc agccctccgc ctgggcgccg aagatcttgt agggcctgtc
    18181 ctcgacgaga ccgagcttga tcagctcctg caggcccttg tcgatcttcg tgagctgcga
    18241 gcccgacgcg atcgggacga cgagctggtc gggcagccgc cagccgagct gctcgcagat
    18301 ctcgtacgcc agggtcttgg agccctccgc gtagtacggg cggaggttga cgttgacgaa
    18361 gccccagccc tcgcccaggg ggtcgccgat gagctcggag cagaagcggt tcacgtcgtc
    18421 gtagttgccc tcgataccga cgagctcgcc gccgtacacc gcggccatga cgaccttgcc
    18481 ctgctccagg tcgtgcggga tgaacacgca ggagcggaaa ccggcccgcg cggcggcggc
    18541 gccgaccgca cccgcgaggt tgccggtgga ggagcaggac agggtggtga agccgaaggc
    18601 gcgggcggcc tcgagggcct gggcgacgac gcggtccttg aaggagtgcg tcgggttgcc
    18661 ggagtcgtcc ttgatgtaca gaccgccggt gacgcccagt tcacgcgcga ggttgtcggc
    18721 cttgacgagg tgggtccagc ccgggttcag gttcggcttg tccgccacgt cggcggggac
    18781 gggcagcagc ggggcgtagc gccagatgtt ggccgggccg gcttcgatct gcttccgcag
    18841 ctcttcgggg ctgccgctcg gcaggtcgta ggcgacttcg agcggcccga aacactccgc
    18901 gcaggcgaaa atggggccga gttcgaaacg ctgtccgcat tcgcggcacg cgagggcggc
    18961 ggcggggccg aggtccacgg aagcggatcc ggtggaggcg gtggcggagg tgctggcgct
    19021 ggtgtttgcg acggtctgcg cagccatgat ggcgaggccc tttctcctca tcttcctcgt
    19081 gacgcatttc gccacaagac ggaattggca ccttccccac cgtgacctcg cggtcggcgg
    19141 gagggttgcc ggggcttcaa cgggccgttc cctctgcccc tctggatgag cggtatggct
    19201 ccggacgtgc ggtccgggcg tttgtgtgct tggacccccg agatgcgagg gtcgttcgcg
    19261 ttgctcaaga ctgtaaccga agccccggac ggttgagata gtcgtccgaa ccgcgagatg
    19321 gatcacacga ccacagttca ccgactgttc gtcgactgcc aagggagacg cgaagtgctc
    19381 gatgaggtgg cccgctggct gagccggcgc tcctggtccg cgtccgaccg ctccctcgac
    19441 cggctgatat ccgccaaggt cagacaggga acgacggtca gtgccgtcct tcccgcgctg
    19501 aacgaggagg cgacggtcgg cgacatcgtc acgatcatcc gccgagagct gatggagaac
    19561 gtcccgctcg tcgacgagct ggtcgtgatc gactccgcct ccagcgaccg cacgtccgag
    19621 gtggccgcgg ccgcgggggc ccgggtggtg caccgcgact cgatcctgcc cggcctgccc
    19681 gccgtggccg gcaagggcga ggtgctgtgg cggtcgctga tggtgaccgg cggcgacatc
    19741 gtctgcttct gcgactcgga cctgcgcgac ttctcgcccg acttcgtctc cggcatcgtc
    19801 ggaccgctgc tgaccgagcc ggaggtccag ttcgtcaagg cgatgtacga ccgccccctc
    19861 ggcggcggcg ccgcacccgg ccccgacggt gtccccgccc agggcggccg ggtgaccgag
    19921 ctggtggcgc ggccgctgct caatctgcac tggccgcagc tcgccggatt cgtccagccg
    19981 ctcggcggcg agtacgcggc acgccgctcg ctgctggaac ggctcccgtt cccggtcggg
    20041 tacggcgtgg agctgggact gctgatcgac tcgctgaacc tggtcggcct cgacgcgttg
    20101 gcccaggtcg acgtcggcac ccgcaagcac cgccatcagg acggacaggc gctcggcaga
    20161 atggccgcga cgatctaccg cacggcgcaa ctccggttgt cccggccgca cttggtacgg
    20221 ccgtcgatca cccagttcga tcgggtgggg aacggcttcg ccccgcggac ctaccgggtg
    20281 gacaccgagg agcggccgcc gatgctcgag atcggtgagt acgcggcgcg tcgcgcggca
    20341 taagcaggac ctgccggtca ttttgcctac atttccgatg tatggcattc atcggatttc
    20401 ttgctccgcc gcgcggcagg caccgcaggc ccacgccctc cggcgcgcac gagcggctga
    20461 cccggttgct cggcgtgctc gccgtcacga ctgccgcgac actcggtccg gccgggccgg
    20521 cgacggcgtc gcagcaggtg gaaatggccc gcaccggcac cacggcggaa cagctgtggc
    20581 tcctgggcgg catcacactg agcctgacag cggcgggcct cgtcgccctc gccgccaccc
    20641 gccaccgccg cgaccgccgc gacccctgag tccgccgccc ggtctgccgc cgcggccgcc
    20701 gacacccctg ggccggaacg gtcgccacgg ccgccgacac ccccaccgga acggtcgccg
    20761 cgccggtcgc cgcgccccga agactccgcg gtggtgatct tgtgctcggc caccgggact
    20821 cctacggtgg ccgggatgcc agggggggcg atcgagggat cgagaggcat aacgggggga
    20881 tggggatggt ggggccgggt ttcgaccgcc agtttcatca gggccggcgc ggccgcgttc
    20941 cgcggccggc aacacttcct ctttccacga ccaccggacg tgacaccacg gccggaagtg
    21001 tcgtgcgtcc cgtcccacgg ggctctcgaa gccccctggc gaagcggcac acaggccgct
    21061 tccgacccgg gaaggacgga cagagaaagc caccatgctg agacaacaca gacacacccg
    21121 tgcagccacg acggccgcgg tcacgctcgc cgccgtcgcg gcgggcgcgc tgggcgccgc
    21181 ccccgcgcag gcggtggtcg gcactccggt cgcgaacggt caactcacgt tcgccgcaca
    21241 gatcgacgtc gggggcgagc gcggctgctc cggtgtcctg gtggacccgc agtgggtcct
    21301 caccgccgcc tcctgcttcg ccgcgaaccc ggcggacacc tccgacgtcg tggccggcgc
    21361 gccgtcactg aagacggtcg tcaccgtggg ccgcaccgac ctgaacgcca cgggcgggca
    21421 cgtcagcgag gtcgccgagc tgatcccgcg tacggaccgc gacctggtga tggcccgtct
    21481 cgccactgcc gccaccggtg tcgccccgat cgcgctcgcc accggtgaac ccgccgcggg
    21541 tgagcggctg cgggtggccg gcttcggccg caccgccgac cagtgggtgc ccgaccgtct
    21601 gcgcagcggc acgtacaccg tctcctccgt gacggacacc tcgctgaacc tcgcggcgga
    21661 cgagggttcg agcatctgca tgggcgacac cggcggcccg gcgttccgtg agcggaacgg
    21721 ggccttcgag ttggtcgccc tcaacagccg gtcctggcaa ggcggctgct tcgcttccaa
    21781 ggagacccgc accggggccg tggacacccg ggtggacgac atcaacccct ggatccagca
    21841 ggtccgttcc ctgccgcagg ggagcactcc gctggccggt gacttcgacg gcgacggcaa
    21901 ggcggacttc ggtgcgatga ccggctacgc caggacgccg gacggccgga accacaccgc
    21961 gctgtggaac ctggtcagcg acggcagcgg cctcgcggag ccgcggaccg cctgggacag
    22021 cggaaccggc agctggaacc gggactccac caagccggtc accggcgact tcaacggcga
    22081 cggcaagacc gacgtggcgg ccttgtacga ctacggcagg agcgcggacg gccgcaaccg
    22141 gactggcctg tggaccttcc tgggcaacgg cagcggcttc gccgccccca ccaaggtctg
    22201 ggagagcgga gcaacgagct ggagctggga cgccggcaag cccgtggccg gtgacttcaa
    22261 cggcgacggc aggaccgacc tcggcgtcct gtaccgctac gcccagacct ccgacggccg
    22321 caaccacacc ggcctgtgga ccttcctcag caacggcacc ggcttcgccg cccccaccaa
    22381 ggtctgggac agcggagccg gcagctggaa ctgggacgcc ggcaagcccg tggccggcga
    22441 cttcaacggc gacggcagga ccgacctcgg cgtcctgtac cgctacgccc agacctccga
    22501 cggccgcaac cacaccggcc tgtggacctt cctcagcaac
//
