LOCUS       NZ_CP107567            22199 bp    DNA     linear   CON 18-NOV-2023
DEFINITION  Streptomyces peucetius strain NA0869 chromosome, complete genome.
ACCESSION   NZ_CP107567
VERSION     NZ_CP107567.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces peucetius
  ORGANISM  Streptomyces peucetius
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8050611)
  AUTHORS   Zhao,E. and Ge,H.
  TITLE     Cytochrome P450 Catalyzes Benzene Ring Formation in the Biosynthesis
            of Trialkyl-Substituted Aromatic Polyketides
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8050611)
  AUTHORS   Zhao,E. and Ge,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2022) School of Life Sciences, Nanjing University,
            No. 163 of Xianlin Avenue, Qixia District, Nanjing, Jiangsu 210033,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: unicycler(0.4.8) v. v. 3
            Assembly Name                     :: NJU_NA0869
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/18/2023 06:49:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,216
            CDSs (total)                      :: 7,126
            Genes (coding)                    :: 6,825
            CDSs (with protein)               :: 6,825
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 303
            CDSs (without protein)            :: 301
            Pseudo Genes (ambiguous residues) :: 0 of 303
            Pseudo Genes (frameshifted)       :: 144 of 303
            Pseudo Genes (incomplete)         :: 227 of 303
            Pseudo Genes (internal stop)      :: 22 of 303
            Pseudo Genes (multiple problems)  :: 85 of 303
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:23:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 301800
            Orig. end                         :: 323999
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP107567.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from IFB-NA0869, Nanjing
            University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22199
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22199
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22199
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12199](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12199
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(237..737)
                     /locus_tag="OGH68_RS01480"
                     /old_locus_tag="OGH68_01480"
     CDS             complement(237..737)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606745.1"
                     /locus_tag="OGH68_RS01480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01480"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_264241423.1"
                     /transl_table=11
                     /translation="MTSPLPSNDAPGRRAGRPAAPAIRRATGADARRLTRLVRGSAAYR
                     GHYAPMVAGYRVGPDYIEAHEVFVAADDSGRVLGFYSLVLSPPELDLMFVADEAQGLGI
                     GRLLIEHLTGRAGTAGLDAVRIVAHPPAEGFYLSVGARRTGTVEARPPAVMWDRPELLL
                     SVS"
     gene            complement(864..3026)
                     /gene="ligA"
                     /locus_tag="OGH68_RS01485"
                     /old_locus_tag="OGH68_01485"
     CDS             complement(864..3026)
                     /EC_number="6.5.1.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="ligA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321416.1"
                     /locus_tag="OGH68_RS01485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01485"
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="WP_264241424.1"
                     /transl_table=11
                     /translation="MTTSPAVTAAPAAVVADAAAYAEAVATATRAASAYYATGESPLDD
                     DAYDRLVRGIAAYEQEHPDETSPVSPVGKVAGGAVSGDVPHTVPMLSLDNVFSPEQLVA
                     WTASVERRTGRPVTVWSVEPKLDGLAVAARYEQGRLARLVTRGDGTAGEDVSHAIGTIA
                     GLPQRLTEPATLEIRGEVLMTDEQFERANAARTGHGGTPFANPRNGAAGSLRARDREYT
                     VEMTFFGYAALALPDSGAELTARLGEWAHSEVMRHVAGLGVHTAHSTPVAPRTLSATAA
                     IQERIAEIAAARPGLPFGIDGIVIKADLAEDQAAAGSGSRAPRWAVAYKLPAVEKVTTL
                     LGVEWNVGRTGIIAPRAVLEPVEIDGSTVTYATLHNPADITRRDLRTGDRVMVYKAGDI
                     IPRIEAPVAHLRTGAEQPVVFPEVCPQCGSGIDTSEQRWRCVRGRDCHAVASVSYAAGR
                     DQLDIEGLGTTRVVQLVDAGLVRDFSDLFGLTREQLLGLDRMGETSTDNLLAALDTART
                     RPLSRVFCALGVRGTGRSMSRRIARHFATMEHIRTADAEALQQVDGIGAEKARTVVAEL
                     AELAPLIDRLTAAGVNMTEPGATYRGAVTEGGGAGPEAGLPEGDQASPGAPARTDQDAG
                     PLHGMTVVVTGAMTGELEKLSRNQMNELIERAGGKSSSSVSKRTSLLVAGANAGSKRDK
                     AEQLGTRIAAPDEFAAMVAGFLDTTV"
     misc_feature    complement(3017..3037)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.52"
                     /tool="antismash"
     misc_feature    3074..3089
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.79"
                     /tool="antismash"
     gene            3216..4640
                     /locus_tag="OGH68_RS01490"
                     /old_locus_tag="OGH68_01490"
     CDS             3216..4640
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003959296.1"
                     /locus_tag="OGH68_RS01490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01490"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_264249849.1"
                     /transl_table=11
                     /translation="MPSHVFADRTAEPPERGTVDALITRTRRLRGDVDAVRPDGASTED
                     DPQGRWQRALCDLALHHLDDLGAHLGQLKEGLPQQAADELARELAEYEADGAVGTGSLL
                     SRVGSAEWNLLTDEVSWSDELYRILGRDPCCGPMSLDELPSVVFAEDQPLLTAMVTDCL
                     VDGRPIDGEFRLVLPDGRVRTVHMMGEPVLDGDGCTASMWAVLRDVSELRRSQRAVRET
                     HDWLQRQQHMEQTERRLAAEMHEAVLPRRSTFPAGGRASLDVAAHCVPSPSGALVGGDW
                     YDTLQLPGGETVLSVGELTGHGVSAASSMAMLLGGLRGMAVAGIRPGPLMTHLNQLLDT
                     SAQPALGSAVCCAYTPRTRTLSWAQAGHPAPLLFRNGTGRALVAPDGVLLGATGGAVYE
                     QAEVALQPGDLLVLHTGGLTRTSAASEPDADRLTALAARFARAVDAQECVRAIVEEFGE
                     QEHEGDACVIVARVIA"
     gene            complement(4666..6162)
                     /locus_tag="OGH68_RS01495"
                     /old_locus_tag="OGH68_01495"
     CDS             complement(4666..6162)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321411.1"
                     /locus_tag="OGH68_RS01495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01495"
                     /product="hypothetical protein"
                     /protein_id="WP_264241425.1"
                     /transl_table=11
                     /translation="MSREPNTRLYDLFGLAGWSKGELARLVNRQAAAMGHPQLATDTSR
                     VRRWIDMGETPRDPVPKVLAALFTERLGRVVTIEDLGFARSGRTGKRRDVQGTDNPDGL
                     PWAPDRTAAVLTEFTGMDLMLNRRGLVGAGAALAAGSALSSAMHDWLKTDPAASRGAAH
                     TSDLLHADPAGYDRYEAAPIGSQEIEALERSVEVFRAWDAARGGGLQRKAVVGQLNEVG
                     GMLAYHHPDHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPDDALDLMKLARTGSGEQTLPRTRAMLHTIEAWAQASMGKGQA
                     MRRTLGEAEELFVSDKGDVPPPSWMQMFDEADLHGMQALAYRTLADHDPSAAGIAQKHA
                     KQALQLREGGRQRSKIFDYISLASACFIADDPEQADRYARLALVSMGETSSHRTWDRLR
                     QMYRLTGQYAGYAKIEDLREEIQIALPRTGSPARPKGAGI"
     misc_feature    6335..6349
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.86"
                     /tool="antismash"
     gene            6399..7517
                     /locus_tag="OGH68_RS01500"
                     /old_locus_tag="OGH68_01500"
     CDS             6399..7517
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060711.1"
                     /locus_tag="OGH68_RS01500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01500"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_264241426.1"
                     /sec_met_domain="APH (E-value: 1.8e-18, bitscore: 66.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSAPPRLQQRSVFTAGTAPYSEPAAGRVPRQAGTAGRP
                     LSGRIDLSGPQGAQLRKAVASVHRICPEFNPVQVLRRSGRSVLIVGTTGRTTAVAKCLL
                     DHSPAWAERLRHEIASYRAFVRHRPPVRVPRLIAADPENCTLVIERMPGRPAALTRHPV
                     EAPPRADVRAVLGAVARLNSWRPPAGMFDAPLDYGSRISRYHELGLFTDRDLGDLQKLL
                     HGLAQAGGRQGMGQFCHGDALLSNILLAPTGPVLVDWEHAGWYLPGYDLATLWSVLGDA
                     PAARRQISQLAQQSGTAARDAFLVNLMLVLTREIRTYETAVQRTMREAPPVPAGQAQPG
                     PSAGEEQRLLLRRLHDDCAMARRAVRAAVGTR"
     misc_feature    6705..6707
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7832..7848
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.45"
                     /tool="antismash"
     gene            7912..9834
                     /locus_tag="OGH68_RS01505"
                     /old_locus_tag="OGH68_01505"
     CDS             7912..9834
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173677.1"
                     /locus_tag="OGH68_RS01505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01505"
                     /product="peptidoglycan recognition family protein"
                     /protein_id="WP_264241427.1"
                     /transl_table=11
                     /translation="MTAGGAVACAALLLPLVSAGPSATAERAPAGSLQGAFAAAADEYG
                     VPESVLLGVSYLQSRWDGHGGAASVTGGYGPMHLTDARTALAEAPHHSHGSEDARGDDT
                     RAARPVAEAALPDPGELPPRLRTLERAAEVSGIGAEQLRDSAAANVRGGAALLAAAQRE
                     LGRPAGQDPADWYGAVARYSGADDVATATAYADDVFDVIRTGQSRTTDSGQRVALEPQP
                     EVAPERAQVRELGLRTADAGRTECPPTVACEWIPAPYEEFGAGDYGNHDQGNRPASQSV
                     DYIIVHDTEASWDTTLKLVQNPQYVSWQYSLRSSDGHIAQHVPLEDVAWHAGNWFVNAK
                     SVGLEHEGFLVAPDAWYTEAMYRTSARLVRYLAKRYDIPLDRQHILGHDNVPGTTTATI
                     RGMHTDPGPYWDWAHYFKLLGKPFTPQAGPRSAVVTIRPEYTEHRPLYTGCVKAGEACA
                     PHGSGAVRLHTGPSESAPLVKDIGLRPGGQDSTTAVNDTGARASTGQQYAVAERRGEWT
                     AIWYLGQKAWFHNPGDRPTAVGAREAVLTPRDGLAEVPVYGRAYPEASAYPAGVPVQAV
                     SPLPYKLLAGQKYVVGDRVPGEYLYATTFDTAGHRVVRGKETYYEIQFGHRVAFVKEAD
                     VRVLR"
     misc_feature    complement(9888..9902)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.22"
                     /tool="antismash"
     gene            10001..12199
                     /locus_tag="OGH68_RS01510"
                     /old_locus_tag="OGH68_01510"
     CDS             10001..12199
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321403.1"
                     /locus_tag="OGH68_RS01510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01510"
                     /product="terpene synthase family protein"
                     /protein_id="WP_264249850.1"
                     /sec_met_domain="T1TS (E-value: 6.8e-85, bitscore: 284.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQPFVLPDFYVPYPARLNPHVEEARRHSKKWARRMEMLEGSGIW
                     KESDLDAHDYALLCAYTHPDCDAEALGLVTDWYVWVFFFDDHFLEVFKRSQDLAGGKAY
                     LDRLPAFMPMDLSQGTPEPTNPVEAGLADLWRRTVPSMSPAWRARFAEATEHLLNESMW
                     ELANIDAGRIANPVEYIEMRRKVGGAPWSAGLVEYAAQAEVPESVAGSRPLRVLRDSFS
                     DAVHLRNDLFSYQREVEDEGENSNGVLVLERFLGCTTQEAAEAVNDLLTSRVQQFENTA
                     LTEVPALCVQKGLSPADCAAIAAYTKGLQDWQSGGHEWHMRSSRYMNDGVATERSSFEG
                     VLGTSALDIRTLFGRPAAARLRTLTHRPQRVGPSWLPEFDLPFPLTLSPHLEHARAASI
                     AWAGRMGLLADIWDEAKLTGFDLALCSAGLDPDATPEELELSAEWLTWGTYGDDYYPVV
                     FGRSRDVEGARLSNERLKDCMPVDEPEAGAGVAVTPMERSLADLWARTAGPMSPGARQS
                     LRNAVDVMLDSWLWELHNQAQHRVPDPVDYIEMRRFTFGSDMTMSLCRLRHEGELPPDL
                     YASGPVRGLENSAMDYACLLNDLFSYQKEIEYEGEVHNAVLVVQTFFDCDHRTAAAMTD
                     ALLRSRLEQFLHTKEHELPLVCEEFGLDEKGRAALDSYVKELEDWLAGILNWHRKVRRY
                     KEEDLRGGASPWRLGAPTGLGTSAVRLSLPAQRSAVRV"
     misc_feature    complement(10002..10017)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.81"
                     /tool="antismash"
     gene            complement(12357..12857)
                     /locus_tag="OGH68_RS01515"
                     /old_locus_tag="OGH68_01515"
     CDS             complement(12357..12857)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="OGH68_RS01515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01515"
                     /product="hypothetical protein"
                     /protein_id="WP_264241428.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLFGGRGPAMIIGNLPEGSPAREVAEGEIPFEVGQLLLALENEEPVHVTDVEDT
                     PVMQGDNLLIVRRLKLSESRISCVQFDRSDNVLVTIASWDRPITDDLYALLKPLPAELF
                     QQG"
     gene            13040..13426
                     /locus_tag="OGH68_RS01520"
                     /old_locus_tag="OGH68_01520"
     CDS             13040..13426
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321399.1"
                     /locus_tag="OGH68_RS01520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01520"
                     /product="hypothetical protein"
                     /protein_id="WP_264241429.1"
                     /transl_table=11
                     /translation="MNDRTTPPLQALPDGEAELRLVVRLHWEDVAALGQEAGRLAARMQ
                     RPVGLDEAASHRLRSRSAGRTTPPATTTPTTPTSAAPSTSGQQLPPATSVSSISARNPA
                     DHARQAIEKINGTAGPGRDMTHTA"
     gene            complement(13484..13699)
                     /locus_tag="OGH68_RS01525"
                     /old_locus_tag="OGH68_01525"
     CDS             complement(13484..13699)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849640.1"
                     /locus_tag="OGH68_RS01525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01525"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_264249851.1"
                     /transl_table=11
                     /translation="MFSGWEKPDLDLSNADWRSGTQGTGDVQIAFVEGFIAMRNGGRPE
                     NPSLIFTPAEWRAFVLNARDGEFDLT"
     gene            complement(13826..14992)
                     /locus_tag="OGH68_RS01530"
                     /old_locus_tag="OGH68_01530"
     CDS             complement(13826..14992)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057880.1"
                     /locus_tag="OGH68_RS01530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01530"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_264241430.1"
                     /transl_table=11
                     /translation="MPAEPVAVVGIGQTKHVAARRDVSLAGLVREAARRALDDAHLDWA
                     DIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPMLRVHTAGSVGGSTALVAANLVAAR
                     VHTTVLTLAFEKQSESNAMWGLSLPVPFQQPLLAGAGGFFAPHVRAYMRRTGAPDTVGS
                     LVAYKDRRNALKNPYAHLHEHGITLEKVQASPMLWDPIRYSETCPSSDGACAMVLTGRA
                     GAARSPRRPAWVHGGAMRSEPTMFAGKDFVSPQAGKDCAADVYRQAGITDPRREIDAVE
                     MYVPFSWYEPMWLENLGFAAEGEGWKLTESGATGLDGDLPVNPSGGVLSTNPIGASGMI
                     RFAEAALQVRGQAGEHQVDGARRALGHAYGGGAQFFAMWVVGREPPAV"
     gene            complement(14982..16025)
                     /locus_tag="OGH68_RS01535"
                     /old_locus_tag="OGH68_01535"
     CDS             complement(14982..16025)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884001.1"
                     /locus_tag="OGH68_RS01535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01535"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_264249852.1"
                     /transl_table=11
                     /translation="MAVVAFAQTRHRRRTDDSSEVEMLMPVLHRVLGATGLRTGDIGFT
                     CSGSSDYLAGRAFSFTMALDGVGAWPPISESHVEMDGAWALYEAWVKLLTGQADTALVY
                     AYGKTSPGEVRDVLTRQLDPYYAAPLWPDPVALAALQAQALIDAGETGEPELAAVAARS
                     RGDASANPHAQLQGEIPRGEYLVRPLRVSDCPPVGDGAAAVILAAGDRARELCGRPAWI
                     RGMDHRIEAHSLGVRDLTRSPSTRLAAERAGAFERPVDTAELHAPFTSQEIVLRRSLDL
                     DDRVRVNPSGGALAANPVMAAGLIRIGEAAARIHRGESDRALAHATSGPCLQQNLVAVL
                     EGEAHAR"
     gene            complement(16091..17047)
                     /locus_tag="OGH68_RS01540"
                     /old_locus_tag="OGH68_01540"
     CDS             complement(16091..17047)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382254.1"
                     /locus_tag="OGH68_RS01540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01540"
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="WP_264241431.1"
                     /transl_table=11
                     /translation="MPDVLRAPLVVEFPFTRSLGPVQSAFLTGLRERTVLGVRTGDGTV
                     LVPPVEYDPVTAEEIRDLVEVHATGTVTTWAWNPHPRRQQPLATPFAWVLVRLDGADTA
                     LLHVLDAPGPEAVHTGMRVRVRWAAERSGAITDIACFEPYGSEPDAAPRAHSGTFPESA
                     AGPVTGIVAPARLDYTYTPGRAQSDHLAALTEHRIVGERCPSCRKVYVPPRGACPTCGV
                     ATGEQVEVGPRGTVTTFCVVNIKAKNLDIEVPYVYAHIALDGAGLALHGRIGGILYDRV
                     RMGLRVEPVWREGARHPDHYRPTGEPDADYDTYRELL"
     gene            complement(17060..17881)
                     /locus_tag="OGH68_RS01545"
                     /old_locus_tag="OGH68_01545"
     CDS             complement(17060..17881)
                     /NRPS_PKS="Domain: ECH (18-265). E-value: 2.6e-53. Score:
                     172.8. Matches aSDomain:
                     nrpspksdomains_OGH68_RS01545_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606695.1"
                     /locus_tag="OGH68_RS01545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01545"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_264241432.1"
                     /transl_table=11
                     /translation="MEHRSDHRTGTEHLGVAREGATLIVTLNRPEAKNALSIAMLVGLY
                     DAWLAADADDTVRSVVLTGAGGSFCAGMDLKALAGAGMEGERYRDRMKADPDLHWKAML
                     RHHRPGKPVIAAVEGYCVAGGTEILQGTDIRVAGESATFGLLEVRRGLFPIGGSTVRLP
                     RQIPRTHALEMLLTGRPYTAAEAERIGLVGRVVSDGTALEAALGIAEQINACGPLAVEA
                     VKASVYETAEMTETDGLAAELERGRPVFDTADAKEGARAFAEKRDPVYRRA"
     aSDomain        complement(17087..17827)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_OGH68_RS01545_ECH.1"
                     /evalue="2.60E-53"
                     /label="OGH68_RS01545_ECH.1"
                     /locus_tag="OGH68_RS01545"
                     /protein_end="265"
                     /protein_start="18"
                     /score="172.8"
                     /tool="antismash"
                     /translation="EGATLIVTLNRPEAKNALSIAMLVGLYDAWLAADADDTVRSVVLT
                     GAGGSFCAGMDLKALAGAGMEGERYRDRMKADPDLHWKAMLRHHRPGKPVIAAVEGYCV
                     AGGTEILQGTDIRVAGESATFGLLEVRRGLFPIGGSTVRLPRQIPRTHALEMLLTGRPY
                     TAAEAERIGLVGRVVSDGTALEAALGIAEQINACGPLAVEAVKASVYETAEMTETDGLA
                     AELERGRPVFDTADAKEGARAFAEK"
     gene            18042..19688
                     /locus_tag="OGH68_RS01550"
                     /old_locus_tag="OGH68_01550"
     CDS             18042..19688
                     /NRPS_PKS="Domain: AMP-binding (8-438). E-value: 2.9e-63.
                     Score: 205.8. Matches aSDomain:
                     nrpspksdomains_OGH68_RS01550_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003900.1"
                     /locus_tag="OGH68_RS01550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01550"
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_264241433.1"
                     /sec_met_domain="AMP-binding (E-value: 4.7e-68, bitscore:
                     228.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYNLADLFESVVDVVPDREALVYIDRPGTGAQRRLDYAALDAAA
                     NRIAHHLLDTGIGPGEHLGLHLYNGIEYLQTVLACLKARIVPVNVNYRYVEDELAHLYR
                     DADITALVFDAEFTERVAAVRPRTGKLRHLVRVGTPPDGAPRLDAVAFADAEAAGSPRR
                     GFAPRSADDRFIIYTGGTTGMPKGVVWRQEDLFFAGLGGGAPTGEPVSRPEELAERVAA
                     GGDGITFFPTPPLMHGTSTLTAFIGFNFGQRVVLHRKFVPHEVLRTIEREKVTSVSLVG
                     DAMLRPLIDALNGPLRGCDLSSLFSVSSSGAIMSDSVRDEFGALAPHVMLLNNFGSSES
                     GFNGTATDDAGPATGFRLRVNARTTVVDPATYEPVKPGGTGRVAQCGHVPLGYYRDPAK
                     SAETFFERDGERWVLLGDMATVDEDGIVTVLGRGSQCINTGGEKVYPEEVEQALKAHPD
                     VYDALVAGVPDRRWGSQVAAVVQLREGVSAPSLDAIRSHCRNRLAGYKIPRRLVITEEI
                     RRSPSGKADYRWAREVVTQAAEGRRPAGGVV"
     aSDomain        18066..19355
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_OGH68_RS01550_AMP-binding.1"
                     /evalue="2.90E-63"
                     /label="OGH68_RS01550_AMP-binding.1"
                     /locus_tag="OGH68_RS01550"
                     /protein_end="438"
                     /protein_start="8"
                     /score="205.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FESVVDVVPDREALVYIDRPGTGAQRRLDYAALDAAANRIAHHLL
                     DTGIGPGEHLGLHLYNGIEYLQTVLACLKARIVPVNVNYRYVEDELAHLYRDADITALV
                     FDAEFTERVAAVRPRTGKLRHLVRVGTPPDGAPRLDAVAFADAEAAGSPRRGFAPRSAD
                     DRFIIYTGGTTGMPKGVVWRQEDLFFAGLGGGAPTGEPVSRPEELAERVAAGGDGITFF
                     PTPPLMHGTSTLTAFIGFNFGQRVVLHRKFVPHEVLRTIEREKVTSVSLVGDAMLRPLI
                     DALNGPLRGCDLSSLFSVSSSGAIMSDSVRDEFGALAPHVMLLNNFGSSESGFNGTATD
                     DAGPATGFRLRVNARTTVVDPATYEPVKPGGTGRVAQCGHVPLGYYRDPAKSAETFFER
                     DGERWVLLGDMATVDEDGIVTVLGRGSQCIN"
     misc_feature    18067..18082
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.03"
                     /tool="antismash"
     CDS_motif       18561..18611
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_OGH68_RS01550_0001"
                     /evalue="6.70E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="OGH68_RS01550"
                     /protein_end="190"
                     /protein_start="173"
                     /score="18.8"
                     /tool="antismash"
                     /translation="FIIYTGGTTGMPKGVVW"
     gene            complement(<19821..20332)
                     /locus_tag="OGH68_RS01555"
                     /old_locus_tag="OGH68_01555"
                     /pseudo=""
     CDS             complement(<19821..20332)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060732.1"
                     /locus_tag="OGH68_RS01555"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="OGH68_01555"
                     /product="alpha/beta fold hydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRNGTELAYRTAGEGEPLICLPGGPMRASAYLGDLGGLTTRRRLV
                     LLDLRGTGGLCRTGRRGHPPLRPPGGRRRGAARARIAERLAATRRVYAPTSVATG"
     gene            complement(20427..21026)
                     /locus_tag="OGH68_RS01560"
                     /old_locus_tag="OGH68_01560"
     CDS             complement(20427..21026)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010048415.1"
                     /locus_tag="OGH68_RS01560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OGH68_01560"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_264241434.1"
                     /transl_table=11
                     /translation="MPIRNTPKPATIDDAPLITGTLTRAFDDDPMMRWFFPDDALREGA
                     LGRYFTTIFTRQYVHHGVCERTEAAAAFWVPPEAQAKAVPDAETVQELQNILGDRAGLF
                     REAVEAAAEHTPREPHWYLALIGADPAAQGQGQGAALLRSGLAQADAAGLPVCLESSKP
                     SNLPFYEHFGFTVRKELRLPGEGPVLWAMRREPRRP"
     misc_feature    complement(21283..21299)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.06"
                     /tool="antismash"
ORIGIN
        1 cctgtgcatg gcggacgcca acacgggcac gcggctcttc tacgaccggc tcggcttcca
       61 cgagatcgag gggccgccgg tgtcacctac ctggggcgcg acaccgggcc agtgggagcc
      121 cgatcgtagg gtggccgccg tggacagacc atctggttcg aacgggtgca caacttccgg
      181 gacttgggcg gctccggcac tgcggacggc ggccgcatcg gaaagggcgt cagaggtcag
      241 gagacggaga gcagcagctc agggcggtcc cacatgacgg ccgggggacg ggcctcgacg
      301 gtgccggtcc gccgggcgcc cacgctcagg tagaacccct ccgcgggcgg gtgcgcgacg
      361 atgcgcacgg cgtcgagacc ggccgtcccg gcccggccgg tcaggtgctc gatcaggagt
      421 cggccgatgc ccagcccctg cgcctcatcg gccacgaaca tcagatccag ctcgggcggc
      481 gacagcacca gcgagtagaa gccgaggact ctgccgctgt cgtctgccgc gacgaacacc
      541 tcgtgcgcct cgatgtagtc ggggccgacc cggtacccgg cgaccatcgg ggcgtagtgc
      601 ccccggtagg cagcggaccc ccgcaccagc cgggtgagcc gcctggcgtc cgcgccggtc
      661 gcgcggcgga tcgccggggc cgccgggcgg ccggcccgtc gcccgggggc atcgttcgat
      721 ggcaggggtg acgtcatgga acaagtatga cgcgcccggg tcggccgccg gggtgccggc
      781 gaccggccgc gcggtccggg aacggttcag acgcctcggg agcggggtgg gcggatacgg
      841 ccgtacccgc ccaccgctcc ggttcacacc gtcgtgtcga ggaagccggc caccatggcg
      901 gcgaactcgt ccggcgcggc gatccgggtg cccagctgct ccgccttgtc cctcttggag
      961 cccgcgttcg ccccggcgac caggagcgag gtgcgcttgg acacgctgga ggacgacttg
     1021 cccccggccc gctcgatgag ctcgttcatc tggttgcggc tcagcttctc cagctcaccc
     1081 gtcatcgcgc cggtcacgac cacggtcatg ccgtggagcg ggccggcgtc ctggtccgtc
     1141 cgcgcaggcg cccccggact tgcctggtcc ccttcgggca ggcccgcttc gggaccggcg
     1201 ccgccgccct cggtcaccgc gccccggtat gtcgcccccg gctcggtcat gttgacgccc
     1261 gcggccgtca gccggtcgat gagcggggcc agctccgcca gttcggccac gaccgtacgg
     1321 gccttctccg cgccgatgcc gtcgacctgc tggagggctt cggcgtcggc cgtgcgtatg
     1381 tgctccatgg tggcgaagtg ccgggcgatc cggcgggaca tggagcggcc ggtgccgcgc
     1441 acaccgaggg cgcagaacac cctcgacagc ggccgggtcc tcgcggtgtc gagggcggcc
     1501 agcaggttgt cggtgctggt ctctcccatc cggtccagcc cgagcagctg ctcgcgggtg
     1561 aggccgaaga ggtcggagaa gtcgcggacc aggccggcgt cgaccagctg gacgacccgg
     1621 gtggtaccga gcccttcgat gtcgagctgg tcccgccccg ccgcgtagga gaccgaggcg
     1681 acggcatggc agtcgcggcc acggacgcat cgccagcgct gttcggaggt gtcgatgccg
     1741 gagccgcact gggggcacac ctcggggaag acgaccggct gctcggcgcc ggtgcgcaga
     1801 tgagcgacgg gggcctcgat gcggggaatg atgtcgcccg ccttgtagac catcacccgg
     1861 tctcccgtgc gcagatcccg gcgggtgatg tcggcggggt tgtgcagcgt ggcgtaggtg
     1921 acggtcgatc cgtcgatctc gaccggctcg agcacggcgc gcggggcgat gatgccggtg
     1981 cggcccacgt tccactcgac accgagcagg gtggtgacct tctccacagc ggggagcttg
     2041 taggcgacgg cccaccgcgg cgcccgggaa ccggagccgg ccgctgcctg gtcctcggcc
     2101 aggtccgcct tgatcacgat cccgtcgatc ccgaacggca ggccggggcg ggcggcggcg
     2161 atctccgcga tgcgttcctg gatcgccgcc gtcgcgctca gggtgcgcgg tgcgaccggg
     2221 gtgctgtggg cggtgtgcac acccagcccc gccacatggc gcatcacctc gctgtgcgcc
     2281 cactcgccga gccgggccgt gagctcggcg ccggagtcgg gcagggccag tgccgcgtag
     2341 ccgaagaagg tcatctcgac cgtgtactcg cggtcccggg cgcgcaggct gcccgccgcg
     2401 ccgttgcgcg gattggcgaa gggcgtgcca ccgtgcccgg tgcgcgcggc gttcgcccgc
     2461 tcgaactgct cgtcggtcat gagcacttcg ccgcggatct cgagcgtcgc cggctcggtc
     2521 agtcgctgcg gcagtccggc gatggtgccg atcgcgtgcg acacgtcctc cccggccgtg
     2581 ccgtcgcccc gggtgacgag ccgggcgagg cgcccctgtt cgtaccgggc ggcgacggcg
     2641 aggccgtcca gcttgggctc gacgctccac accgtgacgg gccggcccgt gcggcgctcc
     2701 acggaagcgg tccaggcgac gagctgctcc ggggagaaga cgttgtccag ggagagcatc
     2761 ggtaccgtgt gcggcacgtc gccggacacc gcgccgcccg ccaccttccc gacgggggag
     2821 accggtgacg tctcgtcggg gtgctcctgc tcgtacgccg cgatgccgcg gaccaggcgg
     2881 tcgtacgcgt cgtcgtccag agggctctcg ccggtggcgt agtacgcgga ggcggcacgg
     2941 gtcgcggtcg cgaccgcctc ggcgtacgcg gcggcatcgg cgaccacggc ggcaggcgcg
     3001 gcagtaacgg cgggtgaagt cgtcatgtcg aacatactgc cgcccaccac tgacaatggc
     3061 cgtggcgcga gactcgaacg cctgtggcac atgccagagg caccaccgga tcgagtgttg
     3121 ccaaatcgct tacggcccct tgccgcctgt gcaacagtcg tacccggtcc ctgtcccaga
     3181 ccctggccgt ggccgcgttt gtatcggagt acgacatgcc gtcccatgtg ttcgcggacc
     3241 gtaccgctga gccgcccgag cgcggaaccg tcgatgcgct gatcacccgg acgcgaagac
     3301 ttcgcggaga cgtcgacgcg gtgcgccccg acggcgcgtc gacggaggac gatccgcagg
     3361 gccgctggca gcgcgccctc tgtgacctgg cgctccacca tctcgacgac ttgggcgcgc
     3421 acttgggaca gctcaaggaa gggctcccgc agcaggccgc cgacgaactc gcccgtgaac
     3481 tcgccgagta cgaggcggac ggcgcggtcg gcaccggctc gctgctcagc cgggtcggca
     3541 gcgccgagtg gaacctcctc accgacgagg tgagctggtc cgacgagctg taccggatcc
     3601 tgggacgcga tccctgctgc ggcccgatgt cgctggacga gctgccgtcc gtcgtgttcg
     3661 ccgaggacca gccgctgctg accgcgatgg tgaccgactg tctcgtcgac ggccggccca
     3721 tcgacggcga gttccgtctc gtcctgcccg acggccgggt gcgcaccgtg cacatgatgg
     3781 gcgagcccgt gctcgacggc gacgggtgca ccgcgtcgat gtgggccgtc ctgcgggacg
     3841 tcagcgaact gcgccgcagc cagcgggccg tccgggagac ccacgactgg ctgcagcggc
     3901 aacagcacat ggagcagacg gagcgccggc tcgcggccga gatgcatgag gccgtgctgc
     3961 cccggcgcag cactttcccc gccggcggca gggcgtcgct ggatgtcgcg gcgcactgcg
     4021 tcccgtcccc gagcggtgcg ctcgtcggcg gcgactggta cgacacgctg caactgcccg
     4081 gcggggaaac ggtcctgagc gtcggcgaac tgacagggca tggagtgagc gccgcctcct
     4141 ccatggcgat gctgctggga gggctgcggg gcatggcggt ggccggtatc cggccgggac
     4201 cgctgatgac gcacctcaac caactcctgg acacctccgc gcagcccgct ctcggcagcg
     4261 cggtgtgctg tgcttacacc ccgcgcacca ggaccctctc gtgggcgcag gccggccacc
     4321 ccgcccccct gctgttccgc aacgggacgg ggcgggccct cgtggcgccg gacggtgtcc
     4381 tgctcggtgc caccggcggt gcggtgtacg agcaggccga agtcgccctc cagccgggcg
     4441 atctgctggt gctgcacacc ggcggcctga cgcgcacgag tgccgcctcg gagcccgatg
     4501 cggaccggct gacggcgttg gcagcgcggt tcgcccgggc cgtggatgct caggagtgcg
     4561 tccgtgcgat cgtcgaggag ttcggtgagc aggagcatga gggcgacgcc tgtgtgatcg
     4621 tggcaagggt catcgcatga agcgggccgc cgcggcggcc ggcggctaga tacccgcgcc
     4681 tttcggccgc gccggggagc cggtgcgcgg cagcgcgatc tggatctcct cgcgcaggtc
     4741 ctcgatcttc gcgtatcccg cgtactgccc ggtcaggcgg tacatctggc gcagcctgtc
     4801 ccatgtccgg tgcgaggagg tctcccccat cgacaccagg gcgagccggg cgtagcggtc
     4861 ggcctgctcc gggtcgtccg cgatgaagca ggcggacgcc agcgagatgt agtcgaagat
     4921 cttcgagcgc tgccggccgc cctcgcgcaa ctgcagtgcc tgcttggcat gtttctgcgc
     4981 gatgcccgcc gccgaggggt cgtggtcggc aagggtgcgg taggccagtg cctgcatgcc
     5041 gtggaggtcg gcctcgtcga acatctgcat ccaactgggc ggcggtacgt cgcccttgtc
     5101 ggagacgaac agttcctcgg cctcaccgag ggtgcgacgc atggcctggc ctttgcccat
     5161 ggatgcctgc gcccatgcct cgatggtgtg cagcatcgcg cgggtgcgcg gcagggtctg
     5221 ctccccggag ccggtcctgg cgagcttcat caggtcgagc gcgtcgtcgg gacggcccag
     5281 atggaccatc tggcgcgcgg cgcgggacag tgcctcaccg gcgcgtgggc ggtcgccgcc
     5341 ctcacgggcc gcgtgggcgg cgatgacgaa gtatttctgc gcggtgggtt cgaggccgac
     5401 gtcgtgggac atccagccgg cgagcaccgc gagattggcg gcaacgcccc acaggcggcg
     5461 ctggagatgg tcggggtggt ggtaggcgag catgccgccc acctcgttga gctgtcccac
     5521 gaccgccttg cgctggaggc cgccgccgcg ggcggcgtcc catgcgcgga acacctcgac
     5581 ggaacgctcc agtgcctcga tctcctgcga cccgatgggg gcggcctcgt accggtcgta
     5641 cccagcgggg tcggcgtgca ggaggtcgga ggtgtgtgcg gcgccccggg aggccgccgg
     5701 atcggtcttg agccagtcgt gcatggcgct gctgagtgct gagcccgcgg caagtgccgc
     5761 gccggcgccc accaggccgc gtcggttgag catgaggtcc attcccgtga attcggtgag
     5821 gaccgccgcc gtacggtcgg gcgcccaggg cagaccgtca gggttgtcgg tgccctggac
     5881 gtcccgccgc ttacccgttc gcccgctccg tgcgaacccg aggtcctcga tggtcacgac
     5941 acgaccgagt cgctcggtga acagagctgc cagcaccttg ggcacgggat cgcgcggggt
     6001 ctcccccatg tcgatccagc gccggacccg cgaggtgtcg gtcgccagct gcggatggcc
     6061 catggcggcc gcctgccggt tcacgagtct tgcgagctca cccttggacc atccggccag
     6121 gccgaacagg tcgtacaggc gggtgttggg ttctctgctc acgtcaagcc cccaggttct
     6181 cggctgagtt gacattaacg cgctgtcatg gggcgggcga gtattcgcca gggttcgcca
     6241 gggttcgcca gatggtgtgc cacccgcgac gcggtgtcag gtaggaaagc gccacctcgc
     6301 cccgtctgcc ggggcacatt ccccagggtg ttgcccatga catgtggggc ggggcagcgc
     6361 acgccacctg tcggcacacg aagggatctg tatcgcccat gtacacagca tcgtcctccg
     6421 tgtccgcccc gccccggctc cagcagcgca gcgtgttcac ggccggtacc gcaccgtatt
     6481 ccgagcccgc cgccggccga gtccccaggc aggccggaac cgccggccga cccctcagcg
     6541 ggaggatcga cctgtccggc cctcagggag cgcagctgcg caaggccgtc gcgtcggtgc
     6601 accggatctg tccggagttc aacccggtgc aggtactgcg ccgcagcgga cgatccgtac
     6661 tgatcgtcgg aacgacgggg cgtaccacgg cggtcgccaa gtgcttactg gaccactcgc
     6721 cggcctgggc cgagcgactc cggcacgaaa tagcttcgta ccgcgccttc gtgcggcacc
     6781 gcccaccggt gcgggtcccg cggctgatcg ccgccgaccc ggagaactgc accctggtga
     6841 tcgagcggat gccggggcgg ccggcggcgc tgacccgtca tccggtggag gccccgccgc
     6901 gtgcggacgt gcgtgccgtg ctgggcgcgg tcgcgcggct gaacagctgg cgcccaccgg
     6961 cggggatgtt cgacgcgccg ctggactacg ggtcacgcat ctcgcgctac cacgaactgg
     7021 ggctgttcac cgaccgggac ctgggtgacc tgcagaagct gctgcacggt ctggcccagg
     7081 ccgggggcag gcaggggatg gggcagttct gtcacgggga cgcgctgctc tccaacatcc
     7141 tcctggcgcc gacgggtccg gtgctggtcg actgggagca cgccggctgg tacctgcccg
     7201 gctacgacct ggcgacgctg tggtcggtac tgggcgatgc ccccgcggca cgccgtcaga
     7261 tcagtcagct cgcccagcag tcgggcaccg cggcccggga cgccttcctg gtgaacctga
     7321 tgctggtcct gacccgggag atccgtacct acgagacggc ggtgcagcgc accatgcgcg
     7381 aggcgccgcc ggtcccggcc ggccaggcac agcccggtcc gtcggccggt gaggaacagc
     7441 ggttgctgct gaggcggctg cacgacgact gcgcgatggc ccgcagggcc gtgcgtgcgg
     7501 cggtcggcac tcgctgacca ccgccacaga gggggaagcg cgctgcgcgc ccggtgtcgg
     7561 cacaccgcgc gcgcagcgca ctgtgctgtg cgccgcggcc gacgcctcgg gcatgtcttc
     7621 cgttcggcgc cgccgccgct gtccgccgaa ggtacgcatc tcctgaacgc ctcggccatt
     7681 ggtccatgcc actgacgcgc cgcaggcccg cgcgccgcgg ccgcgaaagt cgccgaacgg
     7741 cggctgacgt gcaagttcct tgtcggcgag catgattgac ggatcgtctg tgagccgata
     7801 cccatgggcg tgtcccggcc cgcaggtccc gttgcgcatc actcgtcact ggaggctgca
     7861 ttgcaaggat cgactgcccc acggccaggc ggcgcccgcc gccgtcgcgc cttgaccgct
     7921 gggggcgcgg tggcgtgcgc cgctctgctg ctgccgctgg tgtcggcagg tccgtcggcg
     7981 accgcagaac gggccccggc cggttcgctg cagggggcct tcgccgccgc ggccgacgag
     8041 tacggcgtgc cggagagtgt gctgctcggc gtctcctatc tgcagtcccg ctgggacggg
     8101 cacggcggcg cggcgagcgt cacgggcggc tacggcccga tgcatctgac ggacgcgagg
     8161 acggcgctgg ccgaggcgcc gcaccattcg cacggcagtg aggacgcccg cggggacgac
     8221 acgcgtgcgg cccgcccggt cgccgaggcg gcgctgcccg accccggcga actgccgccg
     8281 cgactgcgga cgctggaacg cgcggcagag gtgtcgggca tcggcgccga gcagctgcgg
     8341 gacagtgcgg cggccaacgt ccgaggcggt gccgcgctgc tcgccgcggc acagcgcgag
     8401 ctgggcaggc cggccggcca ggacccggcg gactggtacg gggccgtggc caggtattcc
     8461 ggcgcggacg acgtggcgac ggcgacggcg tacgcggacg acgtcttcga cgtgatccgc
     8521 accggccagt cccggaccac ggacagcggt cagcgggtgg cgctcgagcc gcagccggag
     8581 gtggcgcccg agcgggcgca ggtgcgggag ctggggctgc gcacggccga cgcgggcagg
     8641 accgagtgtc cgccgacggt ggcgtgcgag tggatcccgg cgccgtacga ggagttcggc
     8701 gcgggcgact acggcaacca cgaccagggg aaccggcccg cgtcccagtc ggtcgactac
     8761 atcatcgtcc atgacacgga agcctcctgg gacaccaccc tgaagctggt gcagaacccg
     8821 cagtacgtgt cgtggcagta ctcgctgcgc tcgtcggacg ggcacatcgc gcagcacgtc
     8881 ccgctcgagg acgtcgcctg gcacgccggc aactggttcg tgaacgccaa gtcggtgggc
     8941 ctcgagcacg agggtttcct ggtcgctccg gacgcctggt acaccgaggc gatgtaccgc
     9001 acttcggcgc ggctggtgag gtacctggcc aagcggtacg acatcccgct ggaccggcag
     9061 cacatcctgg gccacgacaa cgtgcccggt acgacgacgg cgacgatccg cggcatgcac
     9121 accgacccgg ggccgtactg ggactgggcg cactacttca agctgctggg caagccgttc
     9181 acgccccagg cggggccgcg cagtgcggtg gtcaccatcc gtcccgagta cacggagcac
     9241 cggccgctct acaccggctg cgtcaaggcc ggggaagcgt gcgcgcccca cggttcgggt
     9301 gcggtgcggc tgcacaccgg gccgagcgag agtgctccgc tcgtcaagga catcggcctg
     9361 cgcccgggtg ggcaggactc gacgaccgcg gtgaacgaca cgggggcgcg cgcgtcgacc
     9421 ggccagcagt acgcggtggc ggagcgccgg ggcgagtgga cggcgatctg gtacctgggg
     9481 cagaaggcct ggttccacaa tccgggcgac cgcccgactg cggtcggcgc gcgggaggcg
     9541 gtgctgacgc cgagggacgg tctcgcggag gtgccggtgt acgggagggc gtacccggag
     9601 gcgtcggcgt atccggcggg cgttccggtg caggctgtct cgccgctgcc gtacaagctg
     9661 ctcgccgggc agaagtacgt ggtcggtgac cgggtgccgg gcgagtatct gtacgcgacc
     9721 acgttcgaca cggcgggcca ccgggtggtg cggggcaagg agacgtacta cgagatccag
     9781 ttcgggcacc gggtggcctt cgtgaaggag gccgatgtgc gggtgctccg gtagaccacg
     9841 gggcgccacc ggtcgtgggg tccggtggcg ccccgttcgc cttgacctat tgtccgacta
     9901 atcgccggaa tgcgtgggcc gtacgggcga agggtagggc tgggccgtca tgaccggtcc
     9961 gcgcctggtg cgcggctgct cccgaaaggc cctggcgcac atggcacagc ccttcgtact
    10021 gccggacttc tatgttccgt atccggcccg cctcaatccg catgtcgagg aggcccggcg
    10081 gcactccaag aagtgggcgc gccggatgga gatgctggag gggtccggca tctggaagga
    10141 gagcgacctc gacgcacacg actacgccct gctgtgtgcc tacacccacc cggactgcga
    10201 cgccgaggcc ctcggcctcg tcaccgactg gtatgtgtgg gtcttcttct tcgacgacca
    10261 ctttctcgag gtcttcaagc gcagtcagga cctggcgggc ggcaaggcgt atctggaccg
    10321 gctgccggct ttcatgccga tggacctgtc gcagggcact ccggagccga cgaacccggt
    10381 ggaggccggg ctcgccgacc tgtggcggcg tacggtgccg agcatgtccc cggcgtggcg
    10441 ggcccggttc gcggaggcca ccgagcatct gctcaacgag tcgatgtggg agctcgccaa
    10501 catcgacgcc ggccggatcg ccaatcccgt ggagtacatc gagatgcgcc ggaaggtcgg
    10561 cggcgccccc tggtccgccg gcctggtgga gtacgcggcg caggccgagg tgccggagtc
    10621 ggtcgccggc tcccgtccgc tgcgagtgct gcgtgactcc ttctccgacg cggtgcatct
    10681 gcgcaacgac ctcttctcgt accagcgcga ggtcgaggac gagggcgaga acagcaacgg
    10741 cgtgctggtg ctggagcggt tcctcggctg tacgacgcag gaggcggcgg aggcggtgaa
    10801 cgatctgctc acctcacggg tccagcagtt cgagaacacc gcgctcaccg aagtgcccgc
    10861 gctgtgcgtc cagaagggtc tctcgccggc ggactgcgcg gcgatcgccg cgtacacgaa
    10921 gggactgcag gactggcagt ccggcggcca cgagtggcac atgcgctcca gccgttacat
    10981 gaacgacggt gtggccacgg agcgttcgtc gttcgagggg gtgctgggca cctccgcgct
    11041 ggacatccgg acgctgttcg gccgtcccgc cgcggcccgg ctgcggacac tgacccaccg
    11101 gccgcagcgg gtggggcctt cgtggctgcc cgagttcgac ctgccgttcc cgttgacgct
    11161 cagccctcat ctggagcatg cccgcgccgc gtccatcgcc tgggccggcc ggatgggtct
    11221 gctggccgac atctgggacg aggcgaagct gaccggcttc gacctggccc tgtgctccgc
    11281 ggggctcgac ccggacgcca cgccggaaga gctggagctc agcgccgagt ggctgacctg
    11341 ggggacgtac ggcgacgact actacccggt ggtcttcgga cggtcccgcg acgtcgaggg
    11401 agccaggctc agcaacgaac ggctcaagga ctgcatgccc gtggacgagc ccgaggccgg
    11461 cgccggggtc gcggtcaccc ccatggagcg cagcctggcg gatctgtggg cgcgtaccgc
    11521 cgggccgatg tccccgggtg cccggcagtc gctgcggaac gcggtcgacg tgatgctgga
    11581 cagctggctg tgggagctgc acaaccaggc ccagcaccgg gtccccgacc cggtcgacta
    11641 catcgagatg cgacggttca ccttcggctc cgacatgacc atgagtctgt gccggctgcg
    11701 gcacgagggc gaactgccgc ccgacctgta cgcgagcggg cccgtgcggg gcctggagaa
    11761 ctcggcgatg gactacgcct gcctgctcaa cgacctcttc tcgtaccaga aggagatcga
    11821 gtacgagggg gaggtccaca acgcggtgct ggtggtgcag acgttcttcg actgcgacca
    11881 ccggacggcc gccgcgatga ccgacgctct cctgcggtcc cggctggagc agttcctgca
    11941 cacgaaggag cacgagcttc ccttggtgtg cgaggagttc ggtctggacg agaaggggag
    12001 ggcggccctc gactcgtatg tgaaggagct cgaggactgg ctggcgggca tcctcaactg
    12061 gcaccggaag gtgcggcgtt acaaggagga ggatctgcgg ggcggcgcgt ccccgtggcg
    12121 gctgggcgcg cccacggggc tcggtacgtc ggcggtccgg ctgtcgctgc cggcccagcg
    12181 gtcggcggtc agggtgtagc gggtcggtgc ggccggtcgg gggtgcggcc ggtccggggt
    12241 gcggctccgg ccggccctgt ctctccggcg gcacgtcggc tgatgcggcg agaggggcac
    12301 gacagaactg cccggggcgg ggccccgggc agtgggtcgg acatcggagg agcggctcag
    12361 ccctgctgga acagctccgc gggcagcggc ttgagcagcg cgtagaggtc gtcggtgatg
    12421 ggccggtccc agctggcgat ggtgacgagc acattgtcgc tgcggtcgaa ctggacgcag
    12481 gagatgcggc tttccgagag cttcagccgg cgcacgatca gcagattgtc accctgcatg
    12541 accggcgtgt cctcgacgtc ggtgacatgg accggctctt cgttctccag cgcgagcagc
    12601 agctgcccca cctcgaaggg gatctccccc tccgcgacct cgcgggccgg cgagccctcc
    12661 ggcaggttgc cgatgatcat tgcgggtccc cggccgccga acaggtcgta gcgcaggaac
    12721 acgccctggc agcttccgtc cggggcgggc agcagtccgg cgccgaggtt tccgggccag
    12781 tcccccgggt ccatggccag gacatcgaag tccgggcccg cgggtgtggc ggcgctgcgg
    12841 cggcggagga aggacataac cgcaatggta cgggtacggg gggactcggc cgagccgggg
    12901 ccggggcctg ttgaacgcgg ctgcccccgt tgccgtatcc atgggagcac cggcggcgga
    12961 gcgtcggtgc gggtgcacgc cccctccgtg tgaggagcag gttcccaccg ggattccgta
    13021 ccgacgtgag gatcattcca tgaacgaccg caccactcct cccctgcagg cccttcccga
    13081 cggcgaggcg gaactgcggc tggtggtccg cctccactgg gaggacgtcg ccgcgctcgg
    13141 gcaggaggcg ggccggctgg cggcccggat gcagcgtccg gtgggtctcg acgaggccgc
    13201 gagtcaccgg ctgcgcagcc gctccgccgg ccgcaccacg ccgccggcga cgacaacgcc
    13261 cacaacgccg acgtcagcgg ccccgtccac gagcggtcag cagctgccgc cggcgacgtc
    13321 ggtctcctca atctccgccc gtaaccccgc cgaccacgcc cgacaggcca tcgagaagat
    13381 caacggtacg gcggggccgg ggcgggacat gacgcacacc gcctgagcgg gcccgtactg
    13441 tcccgccgcg ttcgccgacg ggaggcccgg cgcgccgggc acgtcaggtg aggtcgaact
    13501 cgccgtcccg tgcgttcagc acgaaggcac gccactccgc cggggtgaag atcagcgacg
    13561 ggttctccgg acggccgccg ttgcgcatcg cgatgaatcc ctcgacgaac gcgatctgca
    13621 cgtccccggt gccctgagtg ccggaacgcc agtccgcgtt gctcaggtcg aggtccggct
    13681 tctcccaccc ggaaaacatg tgcgtggttg tggtggtggt ggtgctctcg gccacgtccc
    13741 tgctcctccc gcgtcgtctc ccgggccagc ctagcgacga cacccggtca cggacagggt
    13801 gccgcacgtg acggtacggc ggagatcaca cggcgggcgg ttcgcggccg accacccaca
    13861 tggcgaagaa ctgggccccg ccgccgtagg cgtggccgag cgccctgcgt gccccgtcca
    13921 cctggtgctc gcccgcctgc ccgcgcacct ggagcgcggc ctccgcgaag cggatcatgc
    13981 cggaggcccc gatggggttg gtcgacagca ccccgccgga ggggttgacg ggcaggtcgc
    14041 cgtcgagtcc ggtcgcgccg gactcggtga gcttccagcc ctcgccctcg gcggcgaagc
    14101 ccaggttctc cagccacatc ggctcgtacc aggagaacgg cacgtacatc tccaccgcgt
    14161 cgatctcgcg gcgcgggtcc gtgatgccgg cctgccggta gacgtcggcg gcgcagtcct
    14221 tgccggcctg cggcgacacg aagtccttgc ctgcgaacat ggtcggctca ctgcgcatcg
    14281 ccccgccgtg cacccatgcg ggccgccggg gcgaacgggc ggcgcccgcc cggccggtga
    14341 ggaccatcgc gcacgccccg tcggaggagg ggcaggtctc ggagtagcgg atcgggtccc
    14401 agagcatcgg tgacgcctgg accttctcga gggtgatgcc gtgctcgtgg aggtgcgcgt
    14461 acgggttctt cagcgcgttg cgccggtcct tgtacgcgac cagggagccg accgtgtcgg
    14521 gtgcgccggt gcggcgcatg taggcgcgta cgtgcggggc gaagaagccg cccgcgccgg
    14581 cgagcagcgg ctgctggaag gggaccggca gggacaggcc ccacatggcg ttggactcgg
    14641 actgcttctc gaaggccagg gtgagcaccg tcgtgtgcac ccgcgccgcc accaggttgg
    14701 cggcgacgag ggcggtggaa ccgccgacgg agccggccgt gtggacgcgg agcatcggtt
    14761 tgccgaccgc tccgagcgcg tcggccagat acagctccgg catcatcacg ccctcgaaga
    14821 agtcgggcgc cttgccgatg acgacggcgt cgatgtcggc ccagtccagg tgcgcgtcgt
    14881 cgagggcccg ccgggcggcc tcgcggacca gtccggcgag ggagacgtcg cggcgggcgg
    14941 cgacatgttt cgtctggccg atgccgacga cggcgacggg ctcagcgggc atgggcctct
    15001 ccttcgagga cggcgaccag gttctgctgg aggcagggcc cggaggtggc gtgggcgagc
    15061 gcacggtccg actcgccgcg gtggatccgg gccgcggcct ctccgatcct gatcagtccg
    15121 gcggccatga ccgggttggc ggcgagcgct ccgccggacg ggttgaccct caccctgtcg
    15181 tcgaggtcga gactgcggcg taggacgatc tcctgcgagg tgaagggggc gtgcagctcc
    15241 gccgtgtcga cgggacgctc gaaggctccg gcccgctcgg ccgcgagccg tgtggagggc
    15301 gagcgggtga ggtcccgtac gccgaggctg tgcgcctcga tgcggtggtc catgccgcgg
    15361 atccaggcgg gccgcccgca cagctcgcgg gcccggtcgc cggcggccag gatcacggcg
    15421 gccgcgccgt cgccgacggg cgggcagtcg gagactctca gcggccggac gaggtactcg
    15481 ccgcgcggga tctctccctg aagctgagcg tgcgggttgg ccgaggcgtc accgcggctg
    15541 cgggccgcga cggcggcgag ctccggttca ccggtctcgc ccgcgtcgat cagcgcctgc
    15601 gcctgcaggg cggcgagggc gaccgggtcg ggccagagcg gggccgcgta gtaggggtcg
    15661 agctgccggg tgagcacgtc gcggacctca ccgggcgacg tcttgccgta cgcgtagacg
    15721 agcgctgtgt cggcctggcc ggtcagcagc ttcacccacg cctcgtacag tgcccaggcg
    15781 ccgtccatct cgacgtggga ctcgctgatc gggggccacg cgccgacccc gtcgagcgcc
    15841 atcgtgaacg agaacgcccg gcccgcgaga tagtcgctgg acccggagca ggtgaagccg
    15901 atgtcaccgg tccgcaggcc ggtcgccccg agcacccggt gcagcaccgg catcagcatc
    15961 tcgacctcgg acgagtcgtc cgtgcggcgc cggtggcggg tctgggcgaa ggcgacgacg
    16021 gcgatgtccc tgccggtgcc gctgccgttc ggggtggcgg tgtccctgcc gtccggcgcg
    16081 tcgtaccgcg tcacagcagc tccctgtagg tgtcgtagtc ggcgtccggt tcgccggtgg
    16141 gccggtagtg gtcggggtgc cgggccccct cccgccacac cggctcgacg cgcaggccca
    16201 tgcggacccg gtcgtacagg atgccgccga tgcgtccgtg gagggcgagg ccggcgccgt
    16261 ccagggcgat gtgggcgtag acgtagggca cctcgatgtc gagattcttc gccttgatgt
    16321 tgacgacgca gaaggtggtg accgtgccgc gcgggccgac ctcgacctgc tcccccgtgg
    16381 cgacgccgca ggtggggcag gcgccgcggg gcgggacgta gaccttgcgg caggacggac
    16441 agcgttcgcc gacgatccgg tgctcggtga gggcggcgag gtggtcgctc tgggcgcggc
    16501 cgggcgtgta ggtgtagtcg agcctggcgg gggcgacgat gcccgtcacg ggcccggcgg
    16561 cggattcggg gaaggtgccg ctgtgggcac gcggcgccgc gtcgggctcg ctcccgtacg
    16621 gttcgaagca ggcgatgtcc gtgatcgcgc cgctgcgctc ggccgcccag cgcacccgaa
    16681 cccgcatccc ggtgtgcacg gcctcggggc cgggggcgtc gaggacgtgc aggagggcgg
    16741 tgtccgcgcc gtccaggcgt acgagcaccc aggcgaacgg ggtggcgagc ggctgctgcc
    16801 ggcgcgggtg cgggttccac gcccaggtgg tgacggtgcc ggtggcgtgc acctccacga
    16861 ggtcgcggat ctcctcggcg gtgacggggt cgtactcgac gggcgggacg agcaccgtgc
    16921 cgtcgccggt gcgcacgccg agcacggtgc gctcgcgcag gccggtcagg aaggcgctct
    16981 gcacgggccc gagggagcgg gtgaagggga actcgacgac cagcggggcg cgcagcacat
    17041 cgggcatggg gctctcctct caggcgcgcc ggtagacggg gtcgcgcttc tcggcgaagg
    17101 cgcgggcgcc ctccttcgcg tcggcggtgt cgaagacggg ccggcctcgt tccagttcgg
    17161 cggcgagtcc gtcggtctcg gtcatctccg ccgtctcgta caccgatgcc ttgacggcct
    17221 cgacggcgag cgggccgcag gcgttgatct gttcggcgat gcccagggcc gcttcgaggg
    17281 cggtgccgtc ggagacgaca cgtccgacga ggccgatgcg ttcggcctct gccgcggtgt
    17341 aggggcggcc ggtgagcagc atctccaggg cgtgcgtgcg cgggatctgg cgtggcaggc
    17401 gtacggtcga gccgccgatc gggaagaggc cgcggcggac ctcgaggagt ccgaaggtgg
    17461 cgctctcgcc cgcgaccctg atgtcggtgc cctggaggat ctccgtcccg ccggcgacgc
    17521 agtacccctc gacggcggcg atgaccggtt ttccggggcg gtggtggcgc agcatggcct
    17581 tccagtgcag atcggggtcg gccttcatcc ggtcccggta ccgctcgccc tccatgccgg
    17641 cgccggcgag cgccttgagg tccatgcccg cgcagaagga gccgcccgcc cccgtgagga
    17701 cgacggagcg gacggtgtcg tccgcgtcgg ccgcgagcca ggcgtcgtac aggccgacga
    17761 gcatggcgat cgagagggcg ttcttcgcct ccggccggtt cagggtgacg atcagggtgg
    17821 cgccctcgcg cgccacgccg aggtgctcgg tgcccgtgcg gtggtcgctg cgatgttcca
    17881 tggggaacct cccgtcccag acctggaaca ggttgcagca gccgggcggc cagttcaata
    17941 gtttcctgac actcagtcag attctcttgc ccgtgcccct tcccagttgt gcctgccggc
    18001 gctctaatga cggccaggtt cgccgggtgt caggaggagc ggtggagtac aaccttgccg
    18061 acctgttcga atccgtggtc gacgtcgtgc ccgaccgcga ggcgctcgtg tacatcgacc
    18121 gtcccgggac gggtgcgcag cgccggctcg actacgccgc actcgacgcg gcggccaacc
    18181 ggatcgccca ccatctgctc gacacgggca tcgggcccgg cgagcatctc gggctgcacc
    18241 tctacaacgg gatcgagtat ctgcagaccg tgctggcctg cctcaaggcg cggatcgtgc
    18301 cggtgaacgt caactaccgg tacgtcgagg acgagctggc ccatctgtac cgcgacgccg
    18361 acatcaccgc gctcgtcttc gacgcggagt tcaccgagcg ggtggcagcg gtgcggccac
    18421 ggaccggaaa actgcggcac ctcgtgcgcg tcggcacacc gcccgacggg gcaccgcgcc
    18481 tggacgcggt cgccttcgcc gacgccgagg cggccggctc gccgcggcgc ggcttcgcgc
    18541 cccggtctgc ggacgaccgg ttcatcatct acacgggcgg caccacgggc atgcccaagg
    18601 gggtggtgtg gcgacaggag gacctgttct tcgccgggct gggcggcggc gcaccgaccg
    18661 gcgagcccgt gtcacggccg gaggagctgg ccgagcgggt ggccgcgggc ggcgacggga
    18721 tcaccttctt ccccactccc ccgctgatgc acggcacgtc gacgctcacc gcgttcatcg
    18781 gcttcaactt cggccaacgg gtcgtactgc accgcaagtt cgtgccgcac gaggtgctgc
    18841 gcacgatcga gcgggagaag gtcaccagtg tctcgctggt cggcgacgcg atgctgcggc
    18901 cgctgatcga cgcactgaac ggaccgctcc ggggatgcga cctgtccagc ctcttcagcg
    18961 tctccagctc cggggcgatc atgtcggact cggtgcgcga cgagttcggc gcgctggctc
    19021 cgcacgtcat gctgctgaac aacttcggct cctccgagtc ggggttcaac ggcaccgcga
    19081 ccgacgacgc aggacccgcg accggcttcc ggctgcgggt caacgcccgt acgacggtgg
    19141 tcgatccggc cacgtacgaa ccggtgaagc cgggcgggac cggccgggtc gcgcagtgcg
    19201 ggcacgtacc gctcggctac tacagggacc cggcgaagtc ggcggagacg ttcttcgaac
    19261 gcgacggtga acgatgggtg ctgctcggcg acatggcgac cgtggacgag gacggcatcg
    19321 tcaccgtcct gggccggggc tcgcagtgca tcaacaccgg cggcgagaag gtgtacccgg
    19381 aggaggtcga gcaggcgctc aaggcccacc cggacgtgta cgacgcgctc gtcgcgggcg
    19441 taccggaccg caggtggggc agccaggtgg ccgccgtcgt gcaactgcgc gagggcgtgt
    19501 ccgcacccag tctggacgcg atccggtcac actgccgcaa ccggctggcg ggctacaaga
    19561 tcccccgccg gctggtgatc accgaggaga tccggcgctc gccgagcggc aaggcggact
    19621 accgctgggc ccgggaggtc gtgacccagg cggcggaggg ccgccgtcca gcgggcggcg
    19681 tggtgtgatc agtctccgtc gcccgggccg ccaggcagga tccgctcgcc gttgaagacc
    19741 ccgagccgtt cccggtacag ctccagcggt acgccgttcg ggtcgcggga ggccagcggg
    19801 ccctcgggcc gttccggcgt cggccgcggc gggtccaggg gcagcagcgg gggcgcgccc
    19861 tcgatcacga gccggcggac gagcccgggg tactactcgg ccaggagtac ggcggccgcg
    19921 ccgcccatcg agtggccgac gacatcgacc gggccgagct ccagggcccc gatgaaggcg
    19981 ctcaggtcgt ccctgaacgc ctcgaacccg tagctgccgg gccagtcgct cagcccgtgg
    20041 ccacggaagt cggggcgtac acgcggcggg tcgcggccag gcgctcggcg atgcgtgctc
    20101 gcgcagcgcc tcgacgtcgt ccacctggcg gtcgcagcgg tgggtgcccg cgtcggccgg
    20161 tacggcagag cccgccggtg ccgcgcaggt cgagcagcac gagccgccgg cgggtggtca
    20221 ggccgccgag atcgccgagg tacgcggagg cacgcatcgg cccgcccggc agacagatca
    20281 gcggctcgcc ctcccctgcg gtccggtagg ccagttcagt gccgtttcgc acgacgtgaa
    20341 ggacaaggcg tggacgtccc ccggaggttc ccgcggggac gtccctcggc cgtgcgcgtg
    20401 tggccgtgcg actggggctg tgtccgtcag gggcggcgcg gctcgcgccg catggcccac
    20461 agcaccggcc cctcccccgg cagccgcagc tccttgcgca cggtgaagcc gaagtgctcg
    20521 tagaatggga ggttggacgg tttcgaggac tccagacaga cgggcagacc cgccgcgtcg
    20581 gcctgggcga gccctgagcg cagcagggcg gccccctgcc cctggccctg ggcggccggg
    20641 tcggcgccga tgagtgccag gtaccagtgc ggctcccggg gtgtgtgctc ggcggccgcc
    20701 tcgacggctt cccggaacag cccggcccgg tcaccgagaa tgttctggag ctcctggacg
    20761 gtctccgcgt cgggcacggc cttggcctgc gcctccgggg gcacccagaa cgcggccgcc
    20821 gcctcggtgc gctcacacac tccgtggtgg acgtactgcc gggtgaagat cgtggtgaag
    20881 taacggccca gtgctccctc gcgcaaggcg tcgtcgggga agaaccagcg catcatcggg
    20941 tcgtcgtcga aggcgcgggt cagggtgccg gtgatcagcg gagcgtcgtc gatcgtcgcc
    21001 ggcttcggcg tgttccttat cggcatacgg gccattctgc acttgttgat cttgcggttg
    21061 cggggcgggg cccggtccgt tcaccgagca atgccttgac gggcgccggg ccgggctgaa
    21121 taactgatcc cgaatggaac gaccgaatga tcggtcgtcc ggttcgggac gggagcaagc
    21181 ggatgacgga cctgctggac gcggcggagc ggctgggccg cgaggagctc gaggcgctgc
    21241 aactggagcg gctgcgggcg accttgcgcc acgcgtacga caatgtggcc ttctaccacg
    21301 agtcgttcga caaggcgggg ctccgcccgg aggactgccg ttcgctcgcc gacctcgccc
    21361 ggttcccgtt caccgccaag acggacctgc gggacaacta ccccttcggc atgttcgcgg
    21421 tcgagcagtc ccaggtgcgc cgtatccacg cctccagcgg cacgacgggc cggcccaccg
    21481 tcgtcggcta caccgagcgc gacctggaca cctgggccga catcgtcgcc cgctccctgc
    21541 gcgccgccgg cgcccgcccc ggccacaagg tccatgtggc ctacggctac ggcctgttca
    21601 ccggcggcct cggcgcccac tacggggccg aacggctcgg ctgcaccgtc attccggcgt
    21661 ccggcgggat gaccgcccgc caggtccagc tgatctgcga cttccggccc gagatcatca
    21721 tggtcacccc ctcgtacatg ctcacgctcc tcgacgagtt cgagcgccag ggcgtcgatc
    21781 cgcgcacgac ctcgctcaag gtcggcgtct tcggcgccga gccgtggacg gaggagatgc
    21841 gctgcgagat cgaggaacgg ttcgcgatcg acgccgtcga catctacggg ctctccgagg
    21901 tgatgggccc gggtgtggcg caggaattcg tggagaccaa ggacggcctc cacatctggg
    21961 aggaccactt ctatccggag atcgtcgacc cgttcacggg cgagctgctg ccggacggcg
    22021 aggagggcga gctggtgttc acctcgctca ccaaggaggc catgccggtc atccgctacc
    22081 ggacgaggga cctgacgcgg ctcctgccgg gcacggcacg ggtcttccgg cggatggaga
    22141 aggtgaccgg ccgcagcgac gacatggtga tcctgcgcgg ggtgaacctc ttccccacc
//
