LOCUS       NZ_CP098738            21613 bp    DNA     circular CON 20-NOV-2024
DEFINITION  Bacillus halotolerans strain XE48 chromosome, complete genome.
ACCESSION   NZ_CP098738
VERSION     NZ_CP098738.1
KEYWORDS    RefSeq.
SOURCE      Bacillus halotolerans
  ORGANISM  Bacillus halotolerans
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus.
REFERENCE   1  (bases 1 to 4140100)
  AUTHORS   Wu,X.
  TITLE     Mining and exploiting the important functional proteins and genetic
            resources of marine bacterium Bacillus spp.
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4140100)
  AUTHORS   Wu,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUN-2022) Innovation Engineering Center, Third
            Institute of Oceanography, Ministry of Natural Resources, Daxue Road
            178, Xiamen 361005, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. 0.3.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 942.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025809355.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 15:30:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,201
            CDSs (total)                      :: 4,080
            Genes (coding)                    :: 3,916
            CDSs (with protein)               :: 3,916
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 164
            CDSs (without protein)            :: 164
            Pseudo Genes (ambiguous residues) :: 0 of 164
            Pseudo Genes (frameshifted)       :: 110 of 164
            Pseudo Genes (incomplete)         :: 84 of 164
            Pseudo Genes (internal stop)      :: 25 of 164
            Pseudo Genes (multiple problems)  :: 46 of 164
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:33:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3744929
            Orig. end                         :: 3766542
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP098738.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21613
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="9"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21613
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21613
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11613](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11613
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(77..91)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(169..3855)
                     /locus_tag="NDR85_RS18930"
                     /old_locus_tag="NDR85_18890"
     CDS             complement(169..3855)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042126 - nitrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="NDR85_RS18930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18890"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_263870782.1"
                     /transl_table=11
                     /translation="MKKKKLSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQAHQNPLEAWKSIVENPDKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVITYGPDRNIGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQKTERFIEYAKQYTD
                     FPFFVTLTKEDGVYTAGRFLHAKDIGRQTEHDQWKPAVWNERTSAFAIPQGTMGSRWDG
                     QKKWNLHMIDEETGESIEPRLSVLGIEDEIGTVRIPYFSNEGNRVLERDLPIKKLALDN
                     EDVYVTTVFDLILANYGVNRGIGGKSASSYDDPEPFTPAWQEQVTGIKKEAVIKIAREF
                     AQNAIDTEGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIANAKDWEGAPKLQNGTSFFYFATDQWRYEDQPVSDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFDKNGIDLYKEAEKAGAKTTKDVADYVARQLQEKKLKFAIEDP
                     DNEANFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWLEQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLADEVDMKPVKEAVAAPLLHDTMQEMAQPLGKIKDWSKGECEAV
                     PGKTMPNIQVVERDYKQIFHKMTALGPNAALKPSGTKGMSWSIADEYESLKKRLGEVTS
                     DSVAKGCPNISEAKQAAEAVLTLSSTSNGKVAVKAWESLEDITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIRDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3921..3936)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    4001..4010
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            complement(4073..4549)
                     /locus_tag="NDR85_RS18935"
                     /old_locus_tag="NDR85_18895"
     CDS             complement(4073..4549)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="NDR85_RS18935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18895"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_044159794.1"
                     /transl_table=11
                     /translation="MNQCDYLFFLKQLPMFNEVPLSIVETLLNNGTFIRGSCDQDLSFL
                     HSQSIYIVLKGSIRFIDSRLPEGSQTVALWEKGDVFPIDQKGGMFLSPFISVRTSEDIL
                     MLNIPFYILKKIMSYYPQLQMNFLVMLQQNVFFSYELFLRYMHRSQDENAEPDS"
     misc_feature    complement(4607..4622)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4693..5412
                     /locus_tag="NDR85_RS18940"
                     /old_locus_tag="NDR85_18900"
     CDS             4693..5412
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="NDR85_RS18940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18900"
                     /product="YwiC-like family protein"
                     /protein_id="WP_263870783.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFCLGMVKGGAILWHIPLFLGWLFLYLA
                     VYPVTLALKKKQINPYQKWIFSYSFPACSFLFAAVIHKPSFIWLAFSLLPLFLIHVYYA
                     RQKNERALLNDFVGVLFFCTGGLASCWLGTETLDGWAWFIFAQSALFFIGSSFYVKSVI
                     REKNNRVFACWSWGYHLILPLLSAAFGAGWAVLAFIPSSLRAWFFHGKKWPVQTIGILE
                     IVNACFFFAIMCIWLTR"
     gene            complement(5445..6161)
                     /locus_tag="NDR85_RS18945"
                     /old_locus_tag="NDR85_18905"
     CDS             complement(5445..6161)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="NDR85_RS18945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18905"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_044159797.1"
                     /transl_table=11
                     /translation="MNFLSVRTSDKDLISSDLHQLLESISTKRKIEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKNDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKSRLEKELIHNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VNRSDGILINIALTNQDLAKFCAAARESVNRMLGDLRKQGVISIEDSGKIVLHQRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6272..7459)
                     /locus_tag="NDR85_RS18950"
                     /old_locus_tag="NDR85_18910"
     CDS             complement(6272..7459)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="NDR85_RS18950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18910"
                     /product="NarK/NasA family nitrate transporter"
                     /protein_id="WP_263870784.1"
                     /transl_table=11
                     /translation="MINRQHFQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARIIFMISFILLLFPVFWISMADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAITTFAAPVIAQAAGWKSTVQ
                     MYMVLLALFALLHFFFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEQFDLSPADAGLRTAGFIAVSTLLRPAGGWLADKVSPLRILMFVFAGLTLS
                     GVILSFSPTIGIYAFGALTVAVCSGIGNGTIFKLVPFYFSKQAGIANGVVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVIVIWMYWQERMKTHTERSGHSVN"
     misc_feature    complement(7524..7539)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    7536..7551
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.43"
                     /tool="antismash"
     misc_feature    7542..7555
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.45"
                     /tool="antismash"
     misc_feature    7543..7556
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.87"
                     /tool="antismash"
     misc_feature    7544..7557
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.38"
                     /tool="antismash"
     gene            complement(7594..9264)
                     /gene="argS"
                     /locus_tag="NDR85_RS18955"
                     /old_locus_tag="NDR85_18915"
     CDS             complement(7594..9264)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="NDR85_RS18955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18915"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_044159800.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVILETPKDKTHGD
                     YSTNMAMQLARIAKKAPRQIAEEIVATFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGDAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLAKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIISIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRVDLENFRVPFDVWYSETSLYQNGKIDKALDALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLVNVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIDE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSPIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9261..9689)
                     /locus_tag="NDR85_RS18960"
                     /old_locus_tag="NDR85_18920"
     CDS             complement(9261..9689)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="NDR85_RS18960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18920"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_024123211.1"
                     /transl_table=11
                     /translation="MKQETPITIHVKSVIEDDGNEEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLGEEQGRISIAYDMHVGDEQQHLHNMTITYEGGTHA"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="NDR85_RS18965"
                     /old_locus_tag="NDR85_18925"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="NDR85_RS18965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18925"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 8.9e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="NDR85_RS18965_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="NDR85_RS18965_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10229
                     /locus_tag="NDR85_RS21125"
                     /old_locus_tag="NDR85_18930"
                     /pseudo=""
     CDS             10089..10229
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="NDR85_RS21125"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18930"
                     /product="bacteriocin biosynthesis protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKLPVQQVYSVSGDKVLRKRA"
     gene            10267..11613
                     /gene="albA"
                     /locus_tag="NDR85_RS18975"
                     /old_locus_tag="NDR85_18935"
     CDS             10267..11613
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="NDR85_RS18975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18935"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_044159802.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1073.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 8e-29,
                     bitscore: 97.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.1e-08, bitscore: 31.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 4e-07,
                     bitscore: 27.9, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 2.2e-44, bitscore:
                     149.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.4e-06, bitscore: 25.8,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.2e-20, bitscore: 71.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 7.4e-10, bitscore:
                     37.0, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 9.4e-09, bitscore: 33.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYMRDNVSISDFEYLDLN
                     KTAYELCMLMDGQRTAEQILEEQCAKYDESPEDHKDWYYDMLSMLLNKQVIQLENRARF
                     HKIATSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIDQFKKTADMLYDN
                     GVLTCEITGGEIFVHPNANEILEYVLKKFKKVAVLTNGTLMRKESLEMLKAYKQKIIVG
                     ISLDSVQSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFDSPLVHKLWKAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10282..10560
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_NDR85_RS18975_Subtilosin_rSAM_RRE.1"
                     /evalue="5.50E-31"
                     /identifier="RREFam018.1"
                     /label="NDR85_RS18975"
                     /locus_tag="NDR85_RS18975"
                     /protein_end="98"
                     /protein_start="5"
                     /score="97.8"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYMRDNVSISDFEYLDLNKTAYE
                     LCMLMDGQRTAEQILEEQCAKYDESPEDHKDWYYDMLSMLLNKQVIQL"
     gene            11626..11787
                     /gene="albB"
                     /locus_tag="NDR85_RS18980"
                     /old_locus_tag="NDR85_18940"
     CDS             11626..11787
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="NDR85_RS18980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18940"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_024123213.1"
                     /transl_table=11
                     /translation="MSPAQRKMLLYILSFIFVIGAVVYFVKSDYLFTLISIAIAIIFGM
                     RARKADSR"
     gene            11784..12503
                     /locus_tag="NDR85_RS18985"
                     /old_locus_tag="NDR85_18945"
     CDS             11784..12503
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="NDR85_RS18985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18945"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_099043795.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILENVDLQLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGHFTLCGIEADAGMPQKTSDELKTRRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFNSLAEEFHFSQYTNRRISELSLGNRQKVVLMTGLLLGAPLFILD
                     EPLVGLDVESIEVFYQKMQEYCKAGGTILFSSHLLDVVQRFCDYAAILHHKQIRKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12496..13809
                     /locus_tag="NDR85_RS18990"
                     /old_locus_tag="NDR85_18950"
     CDS             12496..13809
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="NDR85_RS18990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18950"
                     /product="bacteriocin biosynthesis protein AlbD"
                     /protein_id="WP_263870785.1"
                     /transl_table=11
                     /translation="MNNLFPILSLLFKQLYGRQGKKDAIRITAGLAVLALFEIGLIRQA
                     GIDESTLGKTYITLALLFMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSAVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLYWLGRFSFFTVYSIIFGVLLSNLFVKKRR
                     TALLLHAAAFTCVCFSAALMPAVTIPLCAIHMLWAIVIDFPSFLQAPQQQSKMHSFMRT
                     SEFSFYKREWNRFISSKAMLLNYIVMGAFSGFFSFQMMNTGIADQHVVYIVISALLLIC
                     SPIALLYSLEKNDRMLLITLPIKRGTMLWAKYRFYSGLLAGGFILIAMIMGLISGRPIS
                     LLTFLQCMELLLAGAYIRLISDEKKPSFSWQTEQQLWSGFSKYRSYVFCIPLFLATLTG
                     TVISLAVIPIAGLIIVYLLQKQDGGFFDTSGKRERLGS"
     gene            13799..14962
                     /locus_tag="NDR85_RS18995"
                     /old_locus_tag="NDR85_18955"
     CDS             13799..14962
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="NDR85_RS18995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18955"
                     /product="insulinase family protein"
                     /protein_id="WP_256766984.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 1.8e-05,
                     bitscore: 22.7, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLTTDQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYQK
                     QNIIDTFGYAAGRRFMYSANLFFDRQLKTYGTRMIHPLYAEGFHTDAVLNTFVDMSSFP
                     ASLSASAAEKAKAELLLKMEKTFADPFSYSAARLAEEAFGNPMYGTAMFGRKDKLMAVH
                     PKRFLDASEFIADLFSQQKQLNILGNIQSCDVQGHAPQASAVSAVRKPVNQDIFETETR
                     STAGPSVMTLGFDCGDMKDVRDYLAMQLIDGLLGKYGHSALFRHFREKDLAVYHVITRY
                     DIMSNMLLVSVCTDQLHENEIPPRVLEAVSRFHADEPELKKAQQFLINEILLQFDSPEG
                     LLAYMGILRRFSCKKEDLLDSISAVTCRDLLQFIKNLTYIGAHVVRG"
     gene            14968..16245
                     /locus_tag="NDR85_RS19000"
                     /old_locus_tag="NDR85_18960"
     CDS             14968..16245
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="NDR85_RS19000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18960"
                     /product="pitrilysin family protein"
                     /protein_id="WP_044159811.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 8.2e-13, bitscore:
                     46.5, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 3.2e-06,
                     bitscore: 25.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKEAFFQQLDERTDIRYTDKGMKIFRLQFPRAHLRLCNVKTGFG
                     SRDVRLQSETGSRMLPYGTAHFLEHLLFWHNGRNLYSDFFEHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDEQIIAQEKAVITSEIDTALLNHQLHYHYQLIQMLS
                     PASPAAVFPAGRKRDIEDLTICDLQEAYAAAYQPHRMTLFLIGGPEDAETLLPSQLRLE
                     KRSGSRSDRKIVPACPPLASKEVKGDLERPEDTWTGIQIGALPGENGLLTLKLYWDIAS
                     RILFHMDSPFFQEIRQTYRLNIQSLSADVHLSEDGGFLILHSKGAHSSAYIDVASYYIT
                     QQKNRTEAWLEYGKDSLVNAIIYDCDYARKCFEWAAQCEQYDCSFLGLYRTIQQMNSHD
                     LLALIEAMVSSNKAVIHVPQKEVMRQ"
     gene            16242..16943
                     /locus_tag="NDR85_RS19005"
                     /old_locus_tag="NDR85_18965"
     CDS             16242..16943
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="NDR85_RS19005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18965"
                     /product="hypothetical protein"
                     /protein_id="WP_044159813.1"
                     /transl_table=11
                     /translation="MKKSTVFTLLLLLAAMAAYSFGWFHSGAEAAGQYVQLIKNDAARL
                     GLLACAASVLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQHRKLCSRYADDVK
                     LLRDSYRGIRQSYVMAAVLYQVIVFGCMFEIVKAVPFSFHTSPAVTMGLAVLLILYLLF
                     YLRTYLLQLFQHGNLFRKVLVGVLTGAGIWWMLSFTISELLFLIILAAIQQIGSFIYKR
                     FSYRSPASLDL"
     gene            complement(16950..>17304)
                     /locus_tag="NDR85_RS19010"
                     /old_locus_tag="NDR85_18970"
                     /pseudo=""
     CDS             complement(16950..>17304)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="NDR85_RS19010"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="NDR85_18970"
                     /product="YncE family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="VMNGELGPKGVTEISLSPLSRGWL"
     gene            complement(17482..18840)
                     /locus_tag="NDR85_RS19015"
                     /old_locus_tag="NDR85_18975"
     CDS             complement(17482..18840)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="NDR85_RS19015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18975"
                     /product="YncE family protein"
                     /protein_id="WP_044159815.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAEAAQDCLCFCEEETSREAMFQAPIELPEGFVVD
                     PAEAVANVTWNADSLSCVSERCLIQTGPEPDEIGVQFAVRLQGTVTLLVSVSPVRNQYG
                     QGEGAVSVIHNVEIDQVVYYSDEPDDCPDVSDITIENLVVVPPFYGSPLSVTGTIVLVP
                     APEPEPVYAFTANPDDQSVSVIDTNTHTVVTTISLPYQPTRIEKAPDNTSVFVLHYYDR
                     VISVISQDTLSVTASILLDQPPESISFIPGHEFFYVVAGGAINVIGIETLTVERSIPFE
                     GFDVAIDPNGLFAYLLGFGSVQRLDLNTGEVTGTIERDLIVNALETGWPERYLYVLEQE
                     FFFNYLTVIDLNTFTISSTQELEYEGEYGMFKSGSGVYLFDDFTHNLYSVSPSGAGVIG
                     NLPQLARDIAFTPNGEFLYATNFIEQSITVYNTDDYSVETVISLGVSPSDIAI"
     misc_feature    19020..19036
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19069..20214
                     /locus_tag="NDR85_RS19020"
                     /old_locus_tag="NDR85_18980"
     CDS             19069..20214
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="NDR85_RS19020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18980"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_044159817.1"
                     /transl_table=11
                     /translation="MTSVISSSSVGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLENMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDRREYILAIQFFKKAESKLTFVTDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYNEQTTYDIRMIQCQSLFGANFLDLKQYDKAIAHFQKAYTLAEAAQQPQLMG
                     RTLYNIALCKQNQHSLESAIEYVKKSIHVFEESKMVPSLPQAFFLITQIYFKLGKIDNA
                     CEYHKKGRDYSIAAGDTVYLTEFEFLESLYLSGPDEAAIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASTYFLKVEEARQHIQGGVNLYEMEV"
     gene            20198..20317
                     /locus_tag="NDR85_RS19025"
                     /old_locus_tag="NDR85_18985"
     CDS             20198..20317
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326489.1"
                     /locus_tag="NDR85_RS19025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18985"
                     /product="PhrC/PhrF family phosphatase-inhibitory
                     pheromone"
                     /protein_id="WP_024123223.1"
                     /transl_table=11
                     /translation="MKWKYKLLLACLAVSAVFVTVEVSNSSTEHFDVAQRAMI"
     gene            complement(20424..21296)
                     /gene="speB"
                     /locus_tag="NDR85_RS19030"
                     /old_locus_tag="NDR85_18990"
     CDS             complement(20424..21296)
                     /EC_number="3.5.3.11"
                     /GO_function="GO:0008783 - agmatinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="speB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391629.1"
                     /locus_tag="NDR85_RS19030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NDR85_18990"
                     /product="agmatinase"
                     /protein_id="WP_044159819.1"
                     /transl_table=11
                     /translation="MRFDEAYSGKVFIASRPEWEEADAILYGMPMDWTVSYRPGSRFGP
                     GRIREVSIGLEEYSPYLDLDLADLNFFDAGDIPLPFGNPQKSLDMIEEYVDSILEKGKF
                     PMGMGGEHLVSWPVMKAMYKKFPDLAIIHFDAHTDLRVDYEGEPLSHSTPIRKAAELIG
                     PENVYSFGIRSGMKEEFEWAKENGMHISKFEVLEPLKEVLPKLAGRPVYVTIDIDVLDP
                     AHAPGTGTVDAGGITSKELLASVHEIARSEVNVKGADLVEVAPIYDHSEQTANTASKII
                     REMLLGFVK"
ORIGIN
        1 tcctgatcct cccattgctt cggatagccg atacctggct ttgtttctac attattgaaa
       61 tacatatatt cggcaccgga acggtttgtc cacgtgtttt tgcaagtgac gctgcacgtg
      121 tggcagccga tgcatttatc taagttcatg accattccga tttgcgcttt aatcttcaag
      181 ccaatcgacc tccttcagct tgcggatgac cacattcaga tcgcgctgat tccccgtagg
      241 gccatagtag ttaaagccgt agctgagctg ggcatagccg ccgatcatct gtgtcggctt
      301 gacgtgaatc cttgtcggac tgttatgggt gcctccgcgg ttattggtca gttttgtgcc
      361 gggcacgttg atgtggcggt cttgggcatg atgcataaac gccattcctt taggaatacg
      421 gtgagaaaga acggctctcg ctacgacaac gccatttcgg ttgaagcatt caatccaatc
      481 gttgtctcgg atatctgtgt cctctgcatc atctttattc atccacactg tcggcccgcc
      541 gcgaaatagc gtaagcatcg gcagagaatc aaaatacatg ctgtgcacgg accatttgtt
      601 atgcggcgtt aaataattga gaacgatttc tttgccctct tgatcaggcc gtttgcttaa
      661 gaaagggcga tgctggagga tcggtttaaa ggtcgccatc gtttccccga actccatcat
      721 cagctcatga tcgacataat aggattgtct gcctgtcagc gtacgccaag ggattaattt
      781 ttccacattt gtcgtaaacg gcgaatacct gcgcccgcct ttttccgagc ctgtaaatgc
      841 cggagatgtg atcaccgttt tgggctgagc cgtgatttgt tcgaacgtaa agcattcttc
      901 ctcccgctct tcagccagat ctttcagctt cagatttgtg atgtcttcaa gcgattccca
      961 tgcttttacg gcaacttttc cattcgacgt ggacgaaagg gttaaaacgg cttctgccgc
     1021 ctgcttggcc tcgcttatat tcggacatcc ctttgcgaca ctgtctgagg tgacttctcc
     1081 cagccttttt ttgagtgatt cgtattcatc ggcaatcgac cagctcatgc cttttgttcc
     1141 gcttggtttt aaggcggcgt ttgggccgag cgcagtcatt ttatgaaaga tttgcttgta
     1201 gtccctttca acaacttgaa tgttcggcat cgttttcccc gggacggctt cacattcgcc
     1261 tttgctccag tccttaattt ttccgagagg ctgggccatt tcctgcatgg tgtcatggag
     1321 gagcggtgcg gcgacagctt cttttaccgg cttcatatca acttcgtccg cgagatcgga
     1381 gacggctttt gataaagcct tgaaaatatc ccagtctgac ttcgattccc aaggagccga
     1441 aatagccggg gcaaaggggt ggataaacgg atgcatatca gtgctgctga gatcgtgttt
     1501 ttcataccat gtcgccgccg gaagcacgat atcggaatac aaggcggtac cggccattcg
     1561 gaaatcgaga ttgattaaca aatcgagctt tccttccggt gcctgctcga gccatttgat
     1621 ttcttcagga cggatgctgt cgctgtcgtc attcatcaag ccgttcgtcg ttcccaagag
     1681 atgcttgaga aaatattcat gcccttttcc cgaactggag atcagattcg ctctccacac
     1741 gaacaggttt ctcggaaaat tcgcttcatt gtcaggatct tcaatggcaa atttcagttt
     1801 tttctcttga agctggcggg ccacatagtc agcaacatct tttgttgtct tcgcccccgc
     1861 tttttcagct tctttgtaca ggtcaattcc gtttttatca aatgtcggat aagacggaag
     1921 ccacccgagt cttgccgcca gcacattgta gtcggcgtga tgcttgtagc gggaggatgc
     1981 cgcgatcgga gatgctaagt cactgaccgg ctgatcctcg tagcgccact ggtcagtcgc
     2041 aaaatagaaa aaggaagtgc cgttttgcag ctttggcgcc ccctcccaat ccttagcgtt
     2101 ggcgatcgtc tgccagcctt cagcagggcg gagtttttcc tgtcctacat aatgagccca
     2161 gcctccgccg tttacgcctt gggcgcctac cagtaatacg agatttaata ctgcccggta
     2221 gatcgtgtca gagttgaacc agtggttgat ccccgcccct acgataatca tggatcggcc
     2281 ctctgtatcg attgcatttt gggcaaactc tctggctatc ttaatgacgg cttctttttt
     2341 gatccctgtc acctgctcct gccaggctgg cgtaaacggt tcaggatcgt catacgagct
     2401 ggctgatttc cccccgatcc cccgattcac gccgtagtta gccaaaatca agtcaaatac
     2461 ggttgtgaca tagacatctt cattgtccag ggccagtttt tttataggca gatctcgctc
     2521 tagcactctg tttccctcat ttgagaaata agggattcga actgtgccga tttcgtcctc
     2581 tatgccgagc accgaaagcc ggggttcaat cgattcgcct gtttcttcat ctatcatgtg
     2641 caggttccat ttcttttggc cgtcccagcg ggagcccatt gttccttgcg gaatcgcgaa
     2701 tgcgcttgta cgttcattcc acaccgcagg cttccactga tcatgctccg tctgccgccc
     2761 gatgtccttt gcgtgaagaa aacgcccggc cgtatacacg ccatcctctt tagttagagt
     2821 gacaaagaac gggaaatccg tgtattgctt tgcgtactct atgaaacgct ctgtcttctg
     2881 attaacgtaa aactcctgca agatcacatg ccccatcgcc atcgcaagcg cgccgtctgt
     2941 tccttggcgg atgctcagcc agtcatctgc aaatttagag gattccgcga aatcggggct
     3001 gattgagatg accttagcgc ctttatagcg ggcttctgcc aaaaaatgcg catccggcgt
     3061 cctcgttaac ggcacattgg acccccatgt gatgatatag cctgagttgt accaatcact
     3121 gctttccggg acgtctgtct ggtcgcccca gatttgcggt gatgccgggg gaagatccgc
     3181 ataccaatca tagaaactga gcatagggcc gccaatcaaa gacataaacc gcgagcctga
     3241 cgcatggctg atcatggaca tagccggaat cggagaaaac ccgatattcc ggtcagggcc
     3301 gtatgttata accgtataca gcagagaagc agaaatcagc ttcagcacct ccggccattc
     3361 agcgcgcaca aagccgccct ttccccgcgc ctgtttatag gacttcgctt tatccggatt
     3421 ttcaacgatc gatttccatg cttccaaagg gttttgatga gcctgcaatg cttcccgcca
     3481 caaattgatc aggacaccgc gcacgtatgg gtatttcaca cggagcgggc tgtagatata
     3541 ccaggaaaaa cttgccccgc ggggacagcc ccttggctcg aagtcaggca tatcagggcc
     3601 ggttgaagga taattcaaat tttgcccttc ccacgtgacg atgccgtttt tcacataaat
     3661 attccagctg caagatcccg tgcagttgac tccgtgggtg gagcggacaa ctttatcgta
     3721 ctgccatctg tttctatata cattctccca atcgcgatct tcgcgggtgg tttggctatg
     3781 tttatttgaa tggtgttcga taggagagaa atagttcaat ctcctaaaca acggactcaa
     3841 tttctttttc ttcatgagag ttcactcctt ctgagtcagg tgatgctaag ttcactataa
     3901 acagagaaag cgtatttcct tgtgaactat gtcacacact cccctttttt cacagaaagt
     3961 tcacatgagg aagaaggaag ggactttcac aggatgtgat gaaggcggcg ttcaggcagg
     4021 acgcctgagt cattagccgt ctttcattca aagatcaaaa acccggttcc ttttaggaat
     4081 cgggctcagc gttttcatcc tgagatctat gcatgtatcg caaaaacagc tcataagaga
     4141 aaaagacatt ttgctggagc atcaccagaa aattcatttg cagctgcgga taataggaca
     4201 tgattttctt taatatgtaa aaagggatat tgagcataag aatgtcttcg gatgttcgga
     4261 ctgaaatgaa tggagataag aacatcccgc ctttttgatc aatgggaaac acatcgcctt
     4321 tttcccacag cgccacggtt tgcgaccctt caggcagcct gctgtcaata aaacgaatac
     4381 tgccttttaa tacaatataa atggattgag aatggagaaa agatagatcc tgatcacatg
     4441 aaccgcggat aaacgtcccg ttattcagca atgtttcgac aatggataga ggcacttcat
     4501 taaacatagg aagttgtttc aaaaaaaata aatagtcaca ctgattcata gggaagcctc
     4561 ctgtgctaag gatagcttta gtgtagcccg gccgatccat gacagcagtg atgtatttca
     4621 cagatgatat gatgaatgtc acttattggc ggtatttttg cttttataat gaaacaagaa
     4681 aggagtgttt cgatgaaggc gcttattcca aagcagcacg gcgcttgggc catgctgctt
     4741 attccgtttt gcctcggtat ggtgaaggga ggagcgattc tttggcatat ccccctattt
     4801 ttaggctggc tttttcttta tttagctgtt tatcctgtta cgctggcatt aaaaaagaaa
     4861 caaatcaacc cctatcaaaa gtggatattt tcttacagtt ttccagcctg cagctttttg
     4921 tttgccgctg tcatccataa gccgtctttt atctggcttg ccttttcttt gctgccgctg
     4981 tttctcattc atgtgtatta tgcccggcaa aaaaatgaac gagcgctgct gaatgatttt
     5041 gtgggcgtct tattcttttg tacaggcgga ctcgccagct gctggctggg gacggagact
     5101 cttgacggct gggcatggtt tattttcgca caatctgctt tgttttttat cggaagttca
     5161 ttttatgtga agtcggtgat ccgggagaag aataatagag tatttgcctg ctggtcgtgg
     5221 ggctatcacc tgatcctccc cttactttcc gcagcttttg gagcgggctg ggccgttctc
     5281 gcctttatcc ccagcagttt gcgtgcatgg ttttttcatg gaaagaagtg gcctgttcaa
     5341 acgatcggca ttcttgaaat cgtcaatgcg tgcttctttt tcgccatcat gtgtatttgg
     5401 ctaacaagat aaaaacaagg acacattgct gtccttgttt cctcttaatc aatattgcaa
     5461 atctctaacg ggcaattttc gcactcaatc tcacaccgta aatagtcccg ctgatgcagt
     5521 acaatctttc cggaatcctc tattgaaata accccttgtt tgcggagatc acccagcatg
     5581 cggttgacgc tctctcttgc agccgcgcaa aatttcgcca gatcctggtt tgtcagggca
     5641 atgttaatga gaatgccgtc actccggttc accccatagc tgtttgacaa gcggatgagg
     5701 gtggagtaga gcgccccttt tttgccatga agaagaaggt ctctgatttt ggattgaatt
     5761 ttgcgcaaat gggtgctcat ccatttcata aattcaaatg tcaaagcacc gttgtggata
     5821 agttcctttt caagtctgct tttattgatg acgagcactt cgccatcctc cagcactttt
     5881 gcactgagca tatatctcgg ttcttctgtg aaaagtgtta attcaccgac aatatcattt
     5941 ttttggcaga ttcttagcgt caggtctttg ccgtcagacg tcagcttccc gatttcaatg
     6001 agtcctgact gaatcagata aagctcttct gcatccattc cttctcgaaa caggtatgtg
     6061 tgtttttcga tttttctttt tgtactgatg gattccagca attgatgaag atcactggaa
     6121 ataagatcct tatcagatgt tcgaacagag agaaaattca tgagctcacc tcgaagaaaa
     6181 gtcacgttgt gtatctattg taacgtgaaa tcatttgcgc ttttcagaaa aaacttacaa
     6241 tctcgtgaat tccccaatcg ccggcggccc gtcagtttac gctgtgcccg cttctctctg
     6301 tatgtgtttt cattctttcc tgccaataca tccatatgac aatgacaaag cttgctaacg
     6361 cgacttccga aagcgccata aatccgatgg cgtattgtcc cgtcgcctga aatacactcg
     6421 ccaggatcag cggagggaaa aagccgccta atccgcccat ggcagacaca actccgttgg
     6481 cgattcccgc ctgcttagaa aaatagaaag gaaccagttt aaaaatcgtc ccgtttccaa
     6541 tcccggagca caccgcaacc gttaacgccc caaaggcgta aatgccgatc gtcggcgaaa
     6601 acgacaggat gacgcccgat aatgtcaggc cggcaaagac aaacatcagg atgcggagcg
     6661 gactcacttt atcagccagc cacccgcccg caggcctaag cagcgtggat acagcaataa
     6721 aacctgccgt ccgcagcccg gcatccgcag gactcagatc aaactgctca acaagaaagt
     6781 ttggcagata gattgtaaaa gcgacaaagg cgccaaacgt aataaaataa aagagactca
     6841 gaaaccacag cacatgattt cggtaaacgg ctttgatttg agtctttacg gacaccttca
     6901 ctttcttctc atgccggtca ccgaagaaaa agtgcagcaa agcaaataaa gccagcagaa
     6961 ccatatacat ttgcaccgta cttttccacc ccgccgcttg agcaatcacg ggagctgcaa
     7021 atgtagtgat cgcggttccg atattcccgg caccgtaaat accgtttact acgccatgtt
     7081 tttctttagg atagtacttc ggaagagatg taaccccaat ggaaaaaacg gctcccccaa
     7141 tccctaagaa aaaaccgccc gcgattaaat caaacaggga atctgccata ctgatccaaa
     7201 atacggggaa taaaagcaat ataaagctaa tcataaaaat gatccgcgcg ccaaacctgt
     7261 tggtcaaata ccccagcgga atgcggagaa gcgatcctaa tataacgggt atggccgtta
     7321 ccagggagat ttcgcctttg ctcaaatgaa tatctaatgt gatttgggaa ataagtgacg
     7381 aaatcagcac ccaaaccata aaccctgcca ccaagcttaa tgactgcagc gataattgaa
     7441 agtgttgacg gttaatcatt cggcttgccc ctttcactga ttcaataatc agccttatca
     7501 tacaaaaact cggcgaagaa gattgtgaac tatatcacac gattttttaa caaaaaaagg
     7561 acaaagccct ctggctttgt cctttcagct tgtttacatt ttttcaggag ccgatacgcc
     7621 gatcaattga agcgcgttgt tcagcgtgat ttgcgttgct ttcattaaag ctaagcgcgc
     7681 acggcttttc tcttcgtttt cagggtcgat gactttctcc gcattgtaga agctgtgcag
     7741 agctgaagcc aagtcataaa tatagttcgt cacacggtga ggaattcgtt tttccgccgc
     7801 ttccgccact gcctctggga aaccgccgat tgttttcagc agatcgtatt ctttttctga
     7861 ttgaataggg ctgaaatcaa gatctgccgc cggcttaagt ccttgctctt ccccttggcg
     7921 aagcatgctg caaatgcggg catgtgcgta ttgcgcataa tatacagggt tttcgttaga
     7981 tgttgataca gcaagatcca agtcaaaatc catatgcgta tcagcgctgc gcatcgcgaa
     8041 gaaataacgc acggcatcaa ggccgacttc gtcaatcagg tcgcgcatcg ttaccgcttt
     8101 ccccgtccgt ttgctcattt tcattttctc gccgtttttg taaaggtgca cgagctgaat
     8161 gatttctact tccaacgttc ctttttcata gccaagtgct tcgattgccg ctttcatacg
     8221 cgggatgtag ccgtggtggt cggcgcccca tacgttgacc agcttatcaa agccgcggtc
     8281 aagcttgtcc ttatggtagg cgatatcagg aagcaggtat gtgtatgtgc cgtccttttt
     8341 gatcagtacg cggtctttgt catcaccgaa cgttgtggaa cggaaccaag tcgcaccgtc
     8401 ttcctcatag acatggcctt tctcacgcag cgcgtccagc gccttatcga tttttccgtt
     8461 ttggtacagt gatgtttcag aataccacac gtcaaacggc acgcggaagt tttccaagtc
     8521 tacgcgaagc ttttccagct cgtatttcaa accgtactca cggaaaaatg cgaggcgttc
     8581 gctttcttct tcgttgacga aacggtcgcc gtattcctca gcgagacgct ttccgattga
     8641 aatgatatcc tcaccgcggt agccgtcctc cggcatcggt ttttccagtc caagcgcttc
     8701 aaagtaacgg acttccacag aaagcgccag gttgttaatc tggtttccgg catcgttaat
     8761 gtagtattcg cggctcacat cgtaacccgc ttttgcaagc acattgcaca aggaatcgcc
     8821 gacagccgca ccgcgcgcgt ggcctaagtg aaggtcgccc gtcggatttg cagatacgaa
     8881 ttccacttga acgcgttcgc cgtttccgat gtttgtttct ccatacgcgt ctcccgcttc
     8941 caatacagac gggatcagct tcgttaaata ttgattgttc atatagaaat tgataaaacc
     9001 aggaccggcg atatcaagct tttcaataga agcctttcct ttatcaaaag tagcgacaat
     9061 ctcctctgcg atttggcgcg gcgctttttt cgcgattctc gcgagctgca tcgccatatt
     9121 tgttgaataa tcgccgtgtg ttttatcctt cggtgtttct aaaatgacat ttggaatctg
     9181 gctttcttca gccagtcccg ctttcagaac ggctgctttg atttcttctt tcagcacgtc
     9241 cttcatctgt tccgcaatgt tcatgcgtga gttcctccct catacgtgat cgtcatatta
     9301 tgtaaatgct gctgctcgtc tccgacatgc atatcatatg cgatactgat acggccttgt
     9361 tcttcgccga gatcagattg aatcgatttt gtgctcgttt tcagctcaag ctcaccaaat
     9421 gacattttat atttggcgat tgtggaagct ccagtcacga aacgctggtt cattttgaca
     9481 gcacctgatc tcatgacaag cacttcgcct tcgcttactt ttacaatcgt tttcactttg
     9541 cctaagtcgt gttcttcata ataagataga tacactttat tctgtttcac atagtaaaat
     9601 ccggtggtgc ggaattcgat cacttcttcg tttccgtcat cctcgatcac agatttcaca
     9661 tggattgtta tcggtgtctc ttgcttcatt ctgacacgtc cttttcatct ttccactttg
     9721 acttgaatag tataatcatt cggtttgtaa acttcaactg cttctatctt accatcattg
     9781 ctcatcagat ttgaagataa acctcagaaa aagcaattcc tttatagaag agaaaatcat
     9841 accactgatt acctttggga aatattacat ttttccgaat tctaccgttt tcaattcaca
     9901 ttttcttcaa aatatatgta ttgaaatgat aatttgatag ttttaatata aaagtacatc
     9961 aaagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgcgcga catgttcaat cggagccgct tgtttagtgg acggacctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctctggggat aaggttctcc
    10141 ggaaaagggc atagtaaatt actatgccct ttttaactaa aatacaaatt ttaactaaaa
    10201 tctacatctt ggttatacat acacagtgat ttttatattt gaatcatatg tataggggat
    10261 ggtattttgt ttatagagca gatgtttcca tttattaatg aaagtgtaag agtccaccag
    10321 ttgcctgagg gcggcgtgct ggaaattgac tacatgcgtg ataacgtctc gatctctgat
    10381 tttgaatact tagatctcaa caaaacggct tacgagcttt gtatgctgat ggacggtcaa
    10441 agaacggctg aacagatttt agaagagcaa tgcgcaaagt atgatgagtc gccggaagac
    10501 cacaaggact ggtactatga catgctcagc atgcttttga acaagcaggt cattcagcta
    10561 gaaaaccggg cccgctttca caaaatcgcc accagcggaa gcaatgaatt tccgatgccg
    10621 ctgcatgcca cctttgagct gacgcaccgc tgtaatttaa agtgcgccca ctgctattta
    10681 gaaagctcgc cggaagcgct cggcaccgta tccattgatc aatttaagaa aacagctgat
    10741 atgctgtatg ataacggcgt tttaacgtgt gaaatcacag gcggcgaaat tttcgtccat
    10801 ccaaacgcca atgagattct tgaatatgtg ttaaagaaat tcaaaaaagt cgccgtctta
    10861 accaacggaa cgctgatgcg aaaagaaagc ctggagatgt taaaagccta taagcaaaaa
    10921 atcatcgtcg gcatatcact ggatagcgta cagtccgaag tgcatgattc atttagaggg
    10981 agaaaaggct cttttgccca aacctgtaaa acgataaaat tgttgagtga tcatggtatt
    11041 tttgtcagag tcgccatgtc ggttttcgaa aaaaacatgt gggaaatcca cgatatggcc
    11101 caaaaggtgc gcgatctcgg ggcgaaagcg ttctcttaca attgggttga tgatttcgga
    11161 agaggcagag atattgtcca tccgacgaaa gatgccgaac agcaccggaa atttatggag
    11221 tacgagcaaa atgtcattga tgaatttaaa gatttgatcc cgatcattcc gtatgaaaga
    11281 aaacgtgcgg cgaactgcgg cgccggctgg aaatcaattg tgatcagccc gttcggagaa
    11341 gtacgcccgt gcgcactctt cccgaaggaa ttttcattgg gaaatatatt tcatgattca
    11401 tatgaaagca tctttgactc ccctcttgtc cataaattgt ggaaagcgca ggcgccgcgg
    11461 ttcagcgagc attgcatgaa agacaaatgc ccgttcagcg gctattgcgg aggctgttac
    11521 ttaaaagggc tgaactccaa caaataccac agaaaaaaca tctgctcctg ggcgaaaaat
    11581 gaacaattag aagatgtggt ccagcttatt taggagggaa acaatttgtc accagcacaa
    11641 agaaaaatgt tactgtatat cctttcattt atttttgtca tcggcgcggt cgtctacttc
    11701 gtaaaaagcg attatttgtt tacgctgatt tctatcgcca tcgccataat tttcggtatg
    11761 cgcgcgcgga aggctgactc gcgatgagca ttttggatat acacgatgta tccgtttggt
    11821 atgaacggga caacgtcatc ttagaaaacg tggatttaca attagaaaaa ggcgccgttt
    11881 acggactgct tggggtaaac ggcgccggaa aaacaacgct gatcaatacg ctgacagggg
    11941 taaaccgcaa tttcagcggg cactttacgc tgtgcggcat tgaagcggat gccggcatgc
    12001 cgcagaaaac atcagatgag ctgaagaccc gccgctactt tgctgccgat tatccgcttc
    12061 tatttacaga aattacggcg aaggactatg tttctttcgt tcattctttg tatcagaaag
    12121 atttctcaga gcagcaattt aacagtttgg cagaggaatt tcacttttcc caatacacaa
    12181 accggagaat ttccgagctg tctctcggca acaggcaaaa ggttgtgttg atgaccgggc
    12241 tattgctcgg ggctcccctg tttattttgg atgagccgct tgtcggcttg gatgtggagt
    12301 caatagaggt cttttatcag aaaatgcagg agtattgcaa agcaggcgga acgattttgt
    12361 tttcttccca tttgctcgat gtggtgcaga gattttgtga ttatgcggcc attcttcatc
    12421 acaaacagat ccggaaggtc attccgattg gagaggagac tgatcttcgg cgtgaatttt
    12481 ttgaggtgat cggccatgaa taacctgttt ccgattctgt cattgctgtt caaacagctt
    12541 tacggccgcc aaggaaaaaa agacgccatt cgcatcaccg cagggcttgc cgttttggcc
    12601 ttgtttgaaa tcgggctgat ccgccaggca ggcattgatg aatcaacctt aggaaaaaca
    12661 tacatcacgc ttgcgcttct gtttatgaat gcgtacatgg tgtttctctc tgttacatcc
    12721 caatggaagg aatcttacat gaagctgagc tgtctattgc cgatctcttc ccggagcttc
    12781 tggctcgctc agagtgcggt tttgtttgtt gatacttgct tgagaaggac gctgtttttt
    12841 ttcatattac cgctgttctt attcggaaac ggaacgctgt caggagcaca aaccctgtat
    12901 tggctcggca gattttcgtt ttttactgtc tattcgatta ttttcggcgt tttgttaagc
    12961 aatcttttcg tcaaaaaaag gagaacggca ctcctgctgc atgcggcggc atttacctgc
    13021 gtgtgcttca gtgcggcttt gatgcctgcc gtgacgatcc cgctatgtgc gattcatatg
    13081 ctctgggcta ttgtgattga cttcccttca tttttgcagg cgcctcagca gcagagcaaa
    13141 atgcattctt ttatgcggac atcagaattt tcgttttata aaagagaatg gaaccggttt
    13201 atttcctcca aagcgatgct gttaaattat attgtgatgg gggcattcag cggcttcttt
    13261 tcgtttcaga tgatgaacac cggcattgcc gatcagcatg tcgtctatat tgtgattagc
    13321 gctctcctgc tgatctgctc accgattgct ttattgtatt ctcttgagaa aaatgaccgg
    13381 atgctgctga tcacgcttcc gattaaacgc ggaacgatgc tttgggcgaa atatcgcttt
    13441 tattccggtt tattggccgg cgggtttatt ttgattgcca tgataatggg cttgatcagc
    13501 ggccgtccga tttcactttt gacttttctg cagtgtatgg aattgctgct ggcaggggct
    13561 tatattcggt taatttcaga tgaaaaaaag ccgtccttca gctggcagac ggagcagcag
    13621 ctctggagcg gtttctctaa ataccgttcc tatgtatttt gtatccctct ttttttagct
    13681 actttaacag gcactgttat atccttggca gtcattccga ttgccgggct gatcattgtc
    13741 tatttactgc aaaaacagga tggtggtttc tttgatacaa gcggaaaaag agaacggctt
    13801 ggaagttaac ctgctgacga ctgatcaatt ttcaaccatc tcgatcgccg cgagctttct
    13861 gaagccgatc gaaagcgcgg cggaacctga agaagaaacg atctattttt atggcgcggc
    13921 tgcataccag aagcaaaaca tcatcgacac tttcggctat gccgccggcc gccgcttcat
    13981 gtattcagca aatctctttt ttgaccggca gctgaaaacg tacgggaccc gcatgattca
    14041 tccgttatat gctgagggat ttcatacaga tgctgttctg aacacctttg ttgacatgtc
    14101 ctcctttccg gcttctcttt ctgccagcgc agcggaaaag gcaaaagccg aactgctgct
    14161 gaaaatggaa aagacattcg ctgacccgtt ctcctattca gcagcccgtc tggcggagga
    14221 agcctttgga aacccgatgt acggcactgc catgtttggc cggaaagaca agcttatggc
    14281 tgtgcatcct aaacgttttc tggatgcgtc ggaatttatc gctgatttat tttctcagca
    14341 gaaacagctg aacatattag gaaacataca gtcatgtgat gttcagggac atgccccaca
    14401 ggcgtccgcc gtgtctgctg taagaaaacc cgtgaatcag gatattttcg aaacagagac
    14461 acgcagcaca gcaggtccgt ccgttatgac acttggcttt gactgcgggg acatgaaaga
    14521 tgtccgcgat tatttagcca tgcagctgat agacggattg ctcggcaaat acggccattc
    14581 cgctttattt cggcattttc gcgaaaaaga tctggccgtt tatcatgtga tcacccgcta
    14641 tgacatcatg agcaatatgc tgcttgtttc cgtatgcacc gaccagcttc atgaaaacga
    14701 gattcctcca agagttttgg aagctgtatc gcgtttccac gcggatgaac cggaattaaa
    14761 aaaggcacaa caatttttaa tcaatgaaat cctgctgcaa tttgattctc ctgaaggact
    14821 cttagcctat atgggaatcc tgcgccgttt ctcttgcaaa aaagaagact tgctggacag
    14881 catctcagca gtcacgtgcc gcgatttgct gcaattcatc aaaaatctta catatatcgg
    14941 agctcatgta gtaaggggat gagagatatg gaaaaggaag ccttttttca acagctggat
    15001 gaacgaaccg atatcagata cacagacaag ggaatgaaaa tattcaggtt acaattcccc
    15061 cgcgcccatt taagactgtg caatgtcaaa accggctttg gaagccggga tgtccgctta
    15121 cagtcagaaa ccggcagccg gatgctgcca tatggcacag cgcacttttt agaacatctc
    15181 ctcttttggc ataacggccg gaacctgtat agtgattttt ttgaacacgg cgcgctgttg
    15241 aatgcgttca ccacttacac tgatacaaat ttcatgttta cctcattgcc ggatcggctc
    15301 agacaaacca ttccaatcct gcttgacgct ttatggaacc actcgtttga cgagcagatc
    15361 attgctcagg aaaaagccgt gattacaagt gaaatagata cggcgcttct caaccaccag
    15421 cttcattacc attatcagct gatccagatg ctgtctcctg cctcaccagc cgcagtcttc
    15481 cccgcaggca gaaaaagaga cattgaggat ctgacgatct gtgatctgca ggaagcctat
    15541 gctgcagcct accagcccca tcggatgacg ctatttctga ttggcggccc agaagatgcg
    15601 gaaactcttt tgccttccca gctcaggctg gaaaagcgct ctggcagccg ctctgacaga
    15661 aagatcgtcc ctgcgtgccc tcccctcgca tcaaaagagg taaagggtga tctggagcgg
    15721 ccggaagata cttggaccgg aatacaaatc ggggcgctcc caggagaaaa cggacttttg
    15781 accttgaagc tgtattggga cattgcctca cgcatcctgt ttcacatgga ttcgccgttt
    15841 tttcaagaga tccggcaaac gtaccgcttg aatatccaaa gcctgtcagc ggatgttcac
    15901 ttatcagagg atggcggctt tttgatcctt cacagtaaag gggcgcattc ttccgcatat
    15961 atcgatgtgg catcttacta tatcacgcag cagaaaaacc gtaccgaagc ctggcttgag
    16021 tacggcaagg attctttagt caatgcgatc atctatgact gtgattacgc gcgtaaatgc
    16081 tttgaatggg cggcacagtg tgaacagtac gattgctcgt ttctcggcct ttaccgcacc
    16141 attcagcaga tgaattctca tgatttattg gctctcattg aagcaatggt ttcttctaac
    16201 aaagcagtca ttcatgtacc ccagaaagaa gtgatgagac aatgaaaaaa agcactgtct
    16261 ttactttatt attgctgctt gcggccatgg cggcttattc cttcggctgg tttcactcag
    16321 gtgccgaagc cgcgggccaa tatgtacagc tgatcaaaaa tgacgctgcc cgccttgggc
    16381 tgttggcttg tgccgcttcc gtactgatgc tgcccgcctt tctctatctt cactacgtga
    16441 cgcaatctgt caaaaacatg acagcagctt ttcagaaact cacacagtct catcaaagct
    16501 gctgtgactt tcagcatcgc aagctgtgca gccgttatgc cgacgatgta aaattgctgc
    16561 gcgacagcta taggggcatc cgccaatcat atgtgatggc tgctgtattg tatcaggtca
    16621 tcgttttcgg ctgcatgttc gaaatcgtca aggccgttcc cttcagcttt catacgtccc
    16681 ctgccgttac aatggggctt gcggtgttac tgattttgta tttattgttt tatttgcgaa
    16741 cgtacttgct gcagcttttt cagcatggaa acctgttccg aaaagtgctt gtgggagtgc
    16801 tgacaggagc cgggatttgg tggatgctca gttttactat aagtgaactg ctttttctga
    16861 tcatcttagc tgccatccag cagatcggat cttttattta taaacgattc tcttatcgca
    16921 gccctgcttc tctcgatcta taaaaacatc tacattgcaa tcgaggacgg accggcgcca
    16981 accggaatga ccgtcacggc tgaatcatca ctcgtgcggt acacggtcac tgcattgtcg
    17041 ccgggctttg tcgggcgtta ctgtaaggtc atagacatta ggaagagaca cgtttgcgat
    17101 gatcctttgt gcggcagtat taacgacata tgcattgtta ataagaaacg gttcactata
    17161 agactcaggg aaataagccc taatactatc cacgaacata caattgtcct caaagtttca
    17221 aataggcggt caaagccacc ccctgctcaa gggtgacaaa ctgatctctg ttacaccctt
    17281 cggtcccagt tcaccattca tcacgtctgt actccatgta accgaagtga ctgcttccgc
    17341 aggatcaacg acaaacccct ccggaacttc aatcggcact tgaaatggcg cttctcgact
    17401 ggcatcttca tcacaaaaac agaaagatca ttctttttca tgatttctca tcccttttag
    17461 aaatgcacaa tatccagttg attaaatcgc aatgtcactc ggtgaaacgc caagcgatat
    17521 gacagtttcc acagaataat catccgtgtt gtaaacagtg atgctttgct ctataaaatt
    17581 tgttgcatac agaaactcgc cattcggggt aaacgcaatg tctcttgcca attgcggaag
    17641 atttcctatt acgcctgcac cacttggact gacggaatat agattgtgag tgaaatcatc
    17701 aaacaaatac acccctgatc cgctcttgaa cattccatat tcaccttcat actccagctc
    17761 ttgggtgctg ctgatcgtaa atgtattcaa atcaatcacc gtcaaataat tgaaaaagaa
    17821 ttcttgttct aatacataaa ggtaacgttc cggccaaccc gtttctaggg catttacgat
    17881 aagatcccgt tcaatagttc ctgtcacttc acctgtgttt aagtccaatc tttgcactga
    17941 accgaaacca agcagatacg cgaacaatcc atttggatca attgcaacat caaagccttc
    18001 aaaaggaata gacctttcaa cagttaaggt ttcaattcct atcacattta tggcaccacc
    18061 agcgacaaca taaaaaaatt cgtgtccagg tataaaagat atggattccg gcggctgatc
    18121 cagcaaaata gaagctgtaa cactcaatgt gtcttgactg atgacagaaa tgacacgatc
    18181 atagtaatgt aaaacaaaca cagaggtgtt atctggcgcc ttttctatcc ttgtaggttg
    18241 gtatggaaga gaaatcgtcg tcacaacagt atgagtgttg gtatcaatca cagaaaccga
    18301 ctgatcatct ggattcgctg tgaacgcata aacgggttcg ggctccggcg caggtacaag
    18361 cacaatcgtt cccgtcaccg ataatggact gccgtaaaat ggcgggacga caacaaggtt
    18421 ctcgatcgta atgtcactga catccggaca atcatccggt tcatcagaat aatagacaac
    18481 ttgatcgatc tccacattgt gaatgacaga aacagccccc tccccttgtc catattggtt
    18541 tcgcacaggt gagacactga caagaagcgt aacggttccc tgcaggcgga ctgcaaattg
    18601 aacaccgatt tcatcaggct caggccccgt ttgaattaag caacgttcac tgacacaaga
    18661 aaggctgtct gcattccacg tgacgtttgc aacagcttca gccggatcaa cgacaaaccc
    18721 ctcaggcaat tcaatcggcg cttgaaacat cgcttcacga ctggtttctt cctcacaaaa
    18781 acataaacaa tcttgtgcag cttctgcttt ttctttaaag gaaagcttgt ttttcctcat
    18841 ttcatcactt ccttttcaga catacactgc tcacgcagat acaacagaat atggaaggtg
    18901 aatgtatttg cttgtacaaa cagccgaggg taaaagctgt ttttgaagaa attccggcca
    18961 tcatgcggtg taacgaaaga aaagattgcg gtttttttgc gcttctcaca agaatgatga
    19021 tgataaaata tgacatatat agaataatga agggagggat tttcaaacgt gacaagtgtc
    19081 atatcttctt cttccgttgg agaaaagatt aatgaatggt atatgtacat acgccgattc
    19141 agcataccgg atgcggaata tttacgaaga gaaatcaaac aagagctgga tcaaatggaa
    19201 gaagaccagg atcttcattt gtattattca ctgatggaat tccggcacaa tctgatgctt
    19261 gagtatcttg aaccgttaga aaacatgcgg atagaggaac agccgcgact gtccgatttg
    19321 ctgcttgaga ttgataaaaa acaggctcgt ttaaccggac tgcttgaata ctactttaat
    19381 ttcttcagag gtatgtacga actggatcgc cgggaatata tattagccat tcaatttttt
    19441 aaaaaagcag agagcaaact gacttttgtg acagataaaa ttgataaagc tgagttcttt
    19501 ttcaaaatgt cagaagttta ttactatatg aagcaaactt atgtgtccat ggactatgca
    19561 cgtcaagcct ttgaaatata caatgaacaa actacatatg atatcagaat gattcaatgc
    19621 caatccctgt ttggagctaa ctttttggat ctgaaacagt atgataaagc aattgcccat
    19681 ttccaaaaag cttatacact tgctgaggcg gcacagcagc cgcagctaat gggaagaacg
    19741 ctttataata ttgcactttg caagcaaaac caacacagtc ttgaatcagc gatagagtat
    19801 gtaaaaaaat ctattcatgt atttgaagaa tcgaaaatgg ttccttcact gccacaagct
    19861 tttttcctaa ttacacaaat ttattttaaa ttaggcaaga ttgataacgc ttgtgaatat
    19921 cataaaaaag gaagagatta ttcaatagct gccggagaca ctgtgtactt aacggagttt
    19981 gaatttttgg aatctttata cttgtctgga cctgatgaag cagcaataga aaaatgtttt
    20041 gttttccttg aaagtaaaat gatgtatgct gatattgaag actttgcact cgatgttgct
    20101 aagtattatc atcagcagga aaattacaaa aaagcatcta cttatttttt aaaggttgaa
    20161 gaagcaagac agcacattca agggggggtg aatttatatg aaatggaagt ataaattatt
    20221 actcgcttgt ttagctgtga gtgctgtatt tgtcacagta gaagtatcaa attcatctac
    20281 agaacatttt gatgttgcac aacgtgctat gatctaagac cgcctttatc ggcggttttt
    20341 ttcgtcccct ctttccacct tgaataagat gtttgcaaag catgggaaca aaaaacatcc
    20401 agacaagagt ctggatgttt ctcttatttc acaaacccaa gcagcatttc acgaatgatt
    20461 ttgctggctg tgtttgccgt ttgctctgag tggtcgtaaa tcggagctac ttctactaaa
    20521 tcagcgccct tcacgtttac ttctgagcgc gcgatttcat gcacggatgc aagcagttct
    20581 ttagacgtga tgccgcctgc gtcaacggtt cctgttcccg gtgcgtgggc agggtctaat
    20641 acgtcaatgt cgattgtgac atataccgga cggcctgcca gcttcggaag aacctctttc
    20701 agcggctcaa gcacttcaaa cttagagatg tgcatgccgt tttcctttgc ccattcgaac
    20761 tcttctttca taccggaacg gattccgaat gaatacacat tttccgggcc gattaattcc
    20821 gccgctttac ggatcggcgt tgagtgagaa agcggttctc cctcatagtc gacgcgaaga
    20881 tccgtatgtg catcaaaatg aataatcgcc aggtcaggaa atttcttgta cattgctttc
    20941 atgacaggcc atgacacgag atgctccccg cccataccca tcgggaattt tcctttttct
    21001 aaaatgctgt ccacatattc ttcaatcata tcaagacttt tttgcgggtt gccgaatggc
    21061 agcggaatgt cgccggcgtc aaagaagttc aggtccgcca gatcaaggtc cagatacggg
    21121 ctgtattctt caagaccgat tgacacctcg cggattcttc ccgggccgaa gcgtgatccc
    21181 ggacgatagc tcaccgtcca gtccatcggc atgccgtaaa ggatggcgtc cgcctcttcc
    21241 cactctggac ggctcgcgat aaatactttt cctgaataag cttcatcaaa tctcatctat
    21301 aaaaccctcg ctttccttta aaaaagcgca agattcgctc ctgcgccata cattcattat
    21361 ttaatcaggt cactcacaaa tttcggcaga acaaacgccg ctttatgaat atcttttgtg
    21421 taatatttcg tgtcaatatc aaagaaacgg ctgtcttcca ctgcaagcgg atcatatgtt
    21481 ttcgaaccga ttgtaaatgt ccacaaaccg cttgggtatg tcggaatgtt cgccgtatac
    21541 agcttcgtaa tcgggaagat ttcctttacg tcacgctgta catttgtaat taattccggt
    21601 gtgaaccatg ggt
//
