LOCUS       NZ_CP102865            25388 bp    DNA     circular CON 26-JAN-2024
DEFINITION  Paenibacillus polymyxa strain S3 chromosome, complete genome.
ACCESSION   NZ_CP102865
VERSION     NZ_CP102865.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5740272)
  AUTHORS   Yang,S., Jin,D., Li,H., Jiang,L., Cui,J., Huang,W., Rang,J., Li,Y.
            and Xia,L.
  TITLE     Screening of new Paenibacillus polymyxa S3 and its disease
            resistance of grass carp (Ctenopharyngodon idellus)
  JOURNAL   J Fish Dis 46 (1), 17-29 (2023)
   PUBMED   36097971
REFERENCE   2  (bases 1 to 5740272)
  AUTHORS   Yang,S., Jin,D., Li,H., Jiang,L., Cui,J., Huang,W., Rang,J. and
            Xia,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-AUG-2022) State Key Laboratory of Developmental
            Biology of Freshwater Fish, College of Life Science, Hunan Normal
            University, Yuelu, Changsha, Hunan 410006, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-JUL-2021
            Assembly Method                   :: SOAPdenovo v. 2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 164.83x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 02:01:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,183
            CDSs (total)                      :: 5,026
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 157
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 111
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 48 of 70
            Pseudo Genes (internal stop)      :: 10 of 70
            Pseudo Genes (multiple problems)  :: 17 of 70
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:25:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1530930
            Orig. end                         :: 1556318
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102865.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Hunan Normal University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25388
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="5"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..25388
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25388
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15388](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15388)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     gene            934..1974
                     /locus_tag="NWS42_RS07090"
     CDS             934..1974
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688423.1"
                     /locus_tag="NWS42_RS07090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_263560753.1"
                     /transl_table=11
                     /translation="MNIKTIASMAGVSVATVSKIINNYTDISEETRQRVLKIMEETGYR
                     PSSSAKTLATKKSNLVGVIFAGKLNVDFSHPFFVDIINVFKKQIGLLGYDLLFFSNEKF
                     LDNGEDYLARSKYFSVDGCIIIAGDEVEKSVFDLDASPIPCIGVDIELTGASSCYIMSD
                     NQKISMKVVEHFYMNGYREMGFIGIERPSLVIKEREEAFISSLKRFSLDVRPEWIVYGK
                     DYAAEDGYQIAKAWIEQENLPRAIFAATDLLAFGAIRAFKESGLKVPENIAVVGCDDIE
                     ACRYTDPPLTTVKQDKQKIGRLAAMVLFDLMNKQMDTKCIKVEPELVIRTSCGARQHWN
                     PTRVEG"
     gene            complement(2059..3552)
                     /gene="glpK"
                     /locus_tag="NWS42_RS07095"
     CDS             complement(2059..3552)
                     /EC_number="2.7.1.30"
                     /GO_function="GO:0004370 - glycerol kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glpK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210: glycerol kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818622.1"
                     /locus_tag="NWS42_RS07095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycerol kinase GlpK"
                     /protein_id="WP_016818622.1"
                     /transl_table=11
                     /translation="MGKYILSLDQGTTSSRAILFNSEGDVVYSAQREFPQYFPHPGWVE
                     QNANEIWSSILGVIASCLSESGVKAKQIAAIGITNQRESVAVWDKNTGLPVYNVLVWQS
                     RQTSDICEELKRQGHEELFHSKTGLLIDPYFSGTKVKWILDHVEGARERAERGDLLFGT
                     IDSWLIWKLSGGKAHVTDYSNAARTLMYNIYELKWDEELLDILGVPKIMLPEVRPSSEV
                     YAHTVDYHFFGQNVPIAGAAGDQQAALFGQACYEKGMIKNTYGTGCFMLMNTGDQPVES
                     KHGLITTIAWGLEEGKVQYALEGSVFVAGSAIQWLRDGLRMFREAKDSEPYAARVSSTE
                     GVYLVPAFVGLGSPYWDSEVRGAMFGLTRGTTKEHFIRATLESLAYQTKDVLTAMEIDS
                     GITVKMLRVDGGAVLNNFLMQFQSDILDATVERPVIHETTALGAACLAGLAIGYWKSTD
                     ELRKRVRVETSFTPTMDEATRDSLYEGWKKAVNATMAYK"
     gene            complement(3584..4408)
                     /locus_tag="NWS42_RS07100"
     CDS             complement(3584..4408)
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688424.1"
                     /locus_tag="NWS42_RS07100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MIP/aquaporin family protein"
                     /protein_id="WP_019688424.1"
                     /transl_table=11
                     /translation="MSPYAAEFIGTMILIALGGGVCAGVSLKKSFAHASGWIVVGLGWG
                     LAVAIGVYAVGQISGAHLNPAVTLALAFQGSFPWQDVPGYIVAQVLGAMAGAVIVILHY
                     WPHWKETEDTAAKLSVFATGPAIDHPFGNVLSEMIGTFIFVLALLSFGANSFTDGLKPL
                     IVGFLVVSIGLSLGGTTGYAINPARDFGPRLMHYLLPIPGKGASNWKYAWVPIVGPLLG
                     GSFAGPFYQAVFKGSMTPAFWILLGVIVVVLLITFRISRIYKNHKMDHKLTA"
     misc_feature    4364..4379
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.4"
                     /tool="antismash"
     gene            4728..6209
                     /locus_tag="NWS42_RS07105"
     CDS             4728..6209
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372703.1"
                     /locus_tag="NWS42_RS07105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PTS transporter subunit EIIC"
                     /protein_id="WP_263560754.1"
                     /transl_table=11
                     /translation="MLKFLQKIGKSLMLPVATLPAAGILQGLALINYETDIPLGPGVGG
                     FLNHYVTPFLNEGAGAIFGNLALIFSIGVAIGLAGDAVAALSAVIAYLVLTRILAAVPG
                     IFAYIPDDVKLDMGVLGGIFIGGWSAYLFKKYHNIQLPDWLGFFSGKRFVPMITAFTTM
                     ILAILLGMVWSPIQDGIAAFGNWIVGFGGIGSMVFMIANRLLIPLGLHHVLNSIAWFQI
                     GNYTNAAGEVVHGDLTRFFAGDTSAGMFMSGFFPIMMFALPAAALAFIHTAKPEKRKAV
                     ASIFIGSALASFLTGITEPLEFSFMFIAPLLYGIHALLTGLSGLVVYLLDVKLGFSFSA
                     GLIDYLVNMKLSTHPLRMIPIGLVFAFIYYFLFRFIILKFNLKTPGREDDVDDTHLFEA
                     NKSIPVGKRSASSGTQSSQAGQVLTYLGGSDNIQSIDACITRLRLVVKDDKAVNDQALK
                     QLGASGIIRLGNGTLQVIFGTRSEALKDEIQRLMS"
     gene            6407..7696
                     /locus_tag="NWS42_RS07110"
     CDS             6407..7696
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014277625.1"
                     /locus_tag="NWS42_RS07110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_250251245.1"
                     /transl_table=11
                     /translation="MKTVQWQWLVLCLAFLTMISGCSGSLSSKGQSSEANLSNSKKITL
                     TLWYWNRSIDDELLVQAEKQFPNIELKTQKIGGDFKAKLKTTLAARSGEPDIVALNDWM
                     VELFPSADRFYDLKELGADRLKDQYLEWKWNQGITPDGKMIAFPMDTGPTALFYRSDLF
                     EQAGLPSDPEQVSASIRTWDDYMAAGEQLRQKFGSHSFLADNIVNVYNQVLAQHTNLYF
                     KPDGSYIGNQSPDIHLGWKTAVDFHRKHLIANADGWTPEWNASVNNGKIASFVGAIWMK
                     QVLTEAAPDTAGKWRVARAPGGDGNLGGSFISILKSSQHPKEAFEVLTWLQSPEHQLEA
                     YHKIGLFPSTPGVYDDPVMETPEPFFGGQATGLIFAASARQVKNSYFGERYPVIHGIVT
                     RRLANVAKQNADPDSLWTETMQRIERELQR"
     gene            7730..8605
                     /locus_tag="NWS42_RS07115"
     CDS             7730..8605
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014277626.1"
                     /locus_tag="NWS42_RS07115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_250251246.1"
                     /transl_table=11
                     /translation="MLREIWKHRAVYAAISPFYLLFGIFGLFPIGFSLYLAFHKWDGIG
                     DMTYNGWGNFRYLVTDNEFWQAVGNTFVIWVYATIPMLFLALIVAFLLYAPFVKMCTLW
                     RVGFFLPNVTSIVAVAIIFGALFANNFGFLNYLLQLLGLPMIQWLNVPWGIQIAISSMV
                     VWRWMGYNAIIYLAGLQSIPHVLYEAAKIDGATGAQAFFRITIPMLRPVILFTVITSTI
                     GGMQLFTEPQVLVGNDGGAGASGMTIVLYLYRESFINNYFGYGAAVGWGMFLIIALFSI
                     INWKLVQGKK"
     gene            8627..9454
                     /locus_tag="NWS42_RS07120"
     CDS             8627..9454
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372706.1"
                     /locus_tag="NWS42_RS07120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_107734857.1"
                     /transl_table=11
                     /translation="MIQTRAKSIVLYAGLLVGIILSMFPFYWLIVMATRTTSDIYRFPP
                     QLWFGSHFLDNITRVLQQIDFAGAFLNTLFVASSITLLVLFFDSLAGFAFAKFDFPGKK
                     VLFVILLATMMVPSQLSLVPSFVMMASFGWVGTFKALIIPGMVNAFGIFWIRQYAEESI
                     PKELLDAGRMDGCSFFRLYWNVALPILRPAFAFLGAFTFIGAWNDYLWPLIVLTDERKF
                     TLQIALSQLNGIYNTDYAMVIAGTLLAVLPLIILFLFISRQFISDLAAGAIKD"
     gene            complement(10001..11512)
                     /locus_tag="NWS42_RS07125"
     CDS             complement(10001..11512)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372709.1"
                     /locus_tag="NWS42_RS07125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_263560755.1"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     6.6e-07, bitscore: 27.6, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 2.5e-46, bitscore:
                     156.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6e-06, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFFRNIKKQYGNYSRLFKLFQTKNKSYLYDVGTGKVMECTEIEY
                     VFLNNLQVYGDIEEVIKTTKVNDDTLTILIDLIHVAQEQHLFQAPPLLSFALSKDEVLE
                     NARSHLEQVTLELTEQCNMACHYCIYHSGNIDFREFGRRHMSWQVAELAIDYTLKNSGK
                     KVAVTFYGGEPLIEFKLLKHCVDYTLKNGADKDLTFSMTTNLTLMTAEIAEYLSTVPNF
                     GVVCSIDGPKEIHDCRRGFKNGEGTYDKAINGLKHLINAYGEKSNSLISLSMVTPRPAN
                     DVVMKKIQNFFNSLSWVPKDITKNISYVRHSSDIEKTITEKSSMHCYDNPVGNWTIDLM
                     LNNTSISKNTPFTIDFLHKQFSIIHDRILTETPYPDYCLNGCCSPASRRIYVTVNGDFH
                     LCERIGKSPSVGNVYSGIDESVLIDRYIDDYGKESLSQCSKCWAIRLCSVCYVECYDSD
                     KFNIEKKRIACRRSLDMLEHALISYHTILEHKPHLLEELNHITLV"
     aSDomain        complement(11129..11506)
                     /aSDomain="Other_Sactipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a sactipeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_NWS42_RS07125_Other_Sactipeptide_rSAM
                     _RRE.1"
                     /evalue="3.70E-09"
                     /identifier="RREFam021.1"
                     /label="NWS42_RS07125"
                     /locus_tag="NWS42_RS07125"
                     /protein_end="128"
                     /protein_start="2"
                     /score="27.6"
                     /tool="antismash"
                     /translation="FFRNIKKQYGNYSRLFKLFQTKNKSYLYDVGTGKVMECTEIEYVF
                     LNNLQVYGDIEEVIKTTKVNDDTLTILIDLIHVAQEQHLFQAPPLLSFALSKDEVLENA
                     RSHLEQVTLELTEQCNMACHYC"
     gene            complement(11499..13154)
                     /locus_tag="NWS42_RS07130"
     CDS             complement(11499..13154)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818615.1"
                     /locus_tag="NWS42_RS07130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_261991016.1"
                     /transl_table=11
                     /translation="MKKYLSKTRKYVFFYIVVTSVLWIIGIIVPYITGIYIDYLVSKSN
                     ISIILYFVLLLGIINIVNILIQYLTALFSTKLNNLLLYEICNDIYQKIFKTKLSVFKDK
                     DNAYLVDQINNDSSTVVDFFSNNISNLVLQVITIIISGIIVLKADVLLCVIIFSLIPCY
                     IFTYVVFRKKLYKANLKYKKEANEYYSKKVEQINKLVFIKKNVLFNEMNERLNKAFNSL
                     FRVATSQVKTNYIFSNLNQFILIICYIFVIGIGGHKVVIGQMSIGQFTIINTYLSMIIS
                     STSYLLSLASSYQETKVSIERLNDVMNSENDIYGSTTLEDLEKISIKQLGVKYSEESVF
                     RDFSYDFFKGGIYGICGHNGSGKTTLLNTLIGLYSDLYTGEIAFNNCSIKDIDMLDMRR
                     YRISYVEQNPEFLNLPIKEYLKFGITFSKEIASNQDELITAFGLEEIITKANLENILIN
                     ENGSNFSGGEKQKLALIRALSKDSFLTILDEPTSALDSKSVSGLIEILTKQKSRRITIV
                     VSHDQRLLAACDHILNIETQEERDDIGFHSYGVL"
     gene            complement(13419..14066)
                     /locus_tag="NWS42_RS07135"
     CDS             complement(13419..14066)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818614.1"
                     /locus_tag="NWS42_RS07135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_017427401.1"
                     /transl_table=11
                     /translation="MLMLKKMCIVLCGFLLMGMPLGASSNAASNDVKNINLTAINCNVT
                     VTKTSASDFSYEYNKSLYTVTSTLSGSTIYITVKGKGSANGISDRVNILIPDKSYEKIT
                     VESTKSGVSLPELNTNLDITGVDGSSMSVRVPVGYSKAISYDNTKGSGSLTFSKGASDY
                     TVTVKTTASALSVPAGWPLFRPNLTYNYINGAGKAKINITLENSAFSIAAQK"
     gene            complement(14060..15388)
                     /locus_tag="NWS42_RS07140"
     CDS             complement(14060..15388)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372712.1"
                     /locus_tag="NWS42_RS07140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_017427400.1"
                     /sec_met_domain="PTHR43273 (E-value: 6.8e-40, bitscore:
                     135.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2e-14, bitscore: 52.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.4e-10, bitscore: 38.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.5e-16, bitscore:
                     57.2, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKASQYNFIFNDIIENTDKTVLYNSRTGALAVLEPEYYKQFCELT
                     NNGLAINNDTYLKNLIECGYIVEDNMNEKAYVKVNLLKNRFESSNLMLTIAPTMACNFR
                     CVYCFEKDQYHNKTMSEETAQSIVNFVKANASKLDTLNVTWYGGEPLIAMKQIVRISED
                     FLEICKENNIQYTASVITNGYLLNKEKVQTLISCGVNDIQVTVDGPKEVHDLRRPLVSG
                     RGTFDVIMNNLKQIKGMIKIFMRINTDQDNWLNLHEIVGFLKENSLLENVIPYLGLVTP
                     TNGKYEGTKCLTDEMYSKFNLKFMSENDIPISYIYPAPKGNYCSADKYNSFVIDPLGHL
                     YKCWSDIGIIEQCVGNINEDTSVKWNTELLGCYLLYDPTEDEKCSDCKYLPVCLGGCPH
                     NRMADFNICEQYRYNLQEYITECTKVLLAGQLTENKKEVSESC"
     misc_feature    complement(15443..15458)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            15955..16710
                     /locus_tag="NWS42_RS07145"
     CDS             15955..16710
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818612.1"
                     /locus_tag="NWS42_RS07145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_231124978.1"
                     /transl_table=11
                     /translation="MVYLFQVAVCDDDPAMHKILQHFFMCMSVSESFDFNLQFFLSGED
                     LIKSYSSQERYPFHIILLDIEMRELSGIETAKLIRLFPDREVQIIFLTNYPEYMLESFE
                     VQAFQYLLKPLTYKLFVEKINKLCHYMRSSVSHFLSVKNKTEHLVLRHSEIIAISKGEN
                     NYIHNELCIATDSHNYFISGTLKAVYEQLKYPFVFIHRSIIVNLVHIRKFSATSVIMSN
                     EQEFPVGRSHAKSLREAYARFIISRFQEG"
     gene            17103..17729
                     /locus_tag="NWS42_RS07150"
     CDS             17103..17729
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372715.1"
                     /locus_tag="NWS42_RS07150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GHKL domain-containing protein"
                     /protein_id="WP_232795370.1"
                     /transl_table=11
                     /translation="MLMQEKRYKETIRSLSDIKRSIHDFKKQLIFVRACLQEQRTEEGV
                     NHINQTLKNIDSPKLHITTGHLVIDALVNHTFSIANKSGIAFFHQIHINPANISIGSHD
                     LCIVLGNVFDNAIEAVMQLPRKKEHSIHLEIFTDNIALWIYVRNSKSNYLNTAFSTKTY
                     NPPLKKHGYGLLNIQQVIKKYGGYLNTTITDSHFQITIMLPCNNS"
     gene            complement(17855..19273)
                     /locus_tag="NWS42_RS07155"
     CDS             complement(17855..19273)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1153: Amino acid carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016324662.1"
                     /locus_tag="NWS42_RS07155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sodium:alanine symporter family protein"
                     /protein_id="WP_038978208.1"
                     /transl_table=11
                     /translation="MNLVHVLETIDSWMWGAPLLILVMGTGLWLTIRLKMLQIIRLPLA
                     LKLIGKAPDEGSGDVSSFGALSTALAATVGTGSIVGVATAIKLGGPGSLFWMLVAAFFG
                     MATKYAEGLLSVKYRVKDRNGQFSGGPMYYIENGLGRRFKPLAMLFAFSGILVALFGIG
                     TFPQVKAIVSSTESSFGVPTVVTAIIISVLTAVVTIGGLKSIAKVSTKIVPFMSGLYIV
                     VCLIVLIKFAGELPHAIALVLQGAFSTTSATGGFAGATIMLAMRSGVARGIFANEAGLG
                     SAPIAAAAAKTKWPAEQGLISMTGVFIDTMIICNLTGFTLLVTGIWSGNDDGGLMTQHA
                     FSSAFPAGAELVTISLILFAFTTILGWNYYGERCVEYLLGVKWIKPYRYLFIVLVAGGA
                     FIKLDAIWLLADIFNAMMAFPNLIALLGLSGIVVAETRTYMNSLYPNKNKGILAGANVG
                     AAIQVEEKGQTVNS"
     regulatory      complement(19432..19526)
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    19635..19653
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.42"
                     /tool="antismash"
     misc_feature    complement(19676..19691)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.74"
                     /tool="antismash"
     gene            complement(19791..21248)
                     /locus_tag="NWS42_RS07160"
     CDS             complement(19791..21248)
                     /EC_number="3.2.1.-"
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010348049.1"
                     /locus_tag="NWS42_RS07160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="WP_045244845.1"
                     /transl_table=11
                     /translation="MTKTLKGFPKNFLWGGATAANQLEGAFDVDGKGLSSADMIAYVPK
                     SERKNDHAIEISSERLEDILAGKVNARFPKREGVDFYHHYKEDIALFAEMGFKVFRMSI
                     HWSRIFPNGYDAEPNEAGLQFYDNVFDELRKYGIEPLVTLSHYETPLGLTQKYNGWLGR
                     EVVDHYVKYAETVFTRYKDKVKYWLTFNEINVMTMSPFTGGGVVIDRVENKQQAIYQAL
                     HHQFVASALATKRGHEIIPGAQIGCMLARIESYPHTCNPEDILKAQHENQMNLFFTDVH
                     ARGEYPNYMNRYFEENNIVIQTESGDAEILKNNTVDFISFSYYMTLTVSAGPEGEKAAG
                     NLIGGVKNPYLQSSDWGWQIDPIGLRVTLNTFYDRYQKPLFIVENGLGAYDKVEEDGSV
                     HDTYRIDYLRQHIAQMKEAIADGVDLIGYTSWGPIDLVSMSTSEMSKRYGFIYVDLDDD
                     GNGTLQRSKKDSFNWYKNVIATNGEEL"
     gene            21460..22431
                     /locus_tag="NWS42_RS07165"
     CDS             21460..22431
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007431750.1"
                     /locus_tag="NWS42_RS07165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_044787396.1"
                     /transl_table=11
                     /translation="MSNLDQIAKLAGFSKATVSRVLNQSPHVSQETRAKILKIMQELDY
                     VPNRNAISLSKGQTLQIGIITSTINEIVLAFLDSFVEIAGQYEFQTIIYTSGEDKKKEL
                     QAFEDLKRKRVDALVIISCVNDTDFLSTYCKYGPIVAWQRMEHTDIRSVAMDQYEGYML
                     ALKHLIQKGYTRIANAFGRPSSINTHSRQRAYEQIMSEHNLPVLPHWNYSSIYNIRDGE
                     QVVRNLLQHREEFPEAILCANDYVAVGILCEARRQLLRVPEDLAIVGFDNTELAHTMGI
                     TTVQNPIMAQAQNAFFMLSPQLIGRQMELHSLEYSLIERTTT"
     gene            22665..23513
                     /locus_tag="NWS42_RS07170"
     CDS             22665..23513
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818607.1"
                     /locus_tag="NWS42_RS07170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PRD domain-containing protein"
                     /protein_id="WP_044787395.1"
                     /transl_table=11
                     /translation="MIIEKVLNNNVLLTKNDKGKEVIVMGRGISFKKVAGDQVDDHKID
                     KIFMLNENEFTARLTELLNDIPVSHLEVVNEIVTHATEVLDTELSDNIYLTLTDHIHFA
                     IQREEKGLALKNAMLYEIKRFYKKEFAVGLDALQKIENTLGVKLGEDEAGFIALHMVNA
                     RIDGNEMKATLKMTEIVQHILNIITYHYGIVLDESSFSYSRFLTHLQYFAMRVIRKEVI
                     HSGEEFLYNQVKQTYTEAFACAQKINEYLEKTYDQYLSKDEYVYLTIHIHRVTERNNIS
                     G"
     misc_feature    complement(23551..23569)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.98"
                     /tool="antismash"
     misc_feature    complement(25277..25294)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.62"
                     /tool="antismash"
ORIGIN
        1 aggccataca tctttaccgc cgaaaccaat cggttctacg ccgttatctt tgagcacctt
       61 cataacattc accagttcgt cccatgtcgt gggcacagca agattatatt tttcaaaaat
      121 ctctttgtta taaaacagtc ctgtcagggc caccttcccc atgttcacac catatacctt
      181 gtcgttatag gtcatggcat ttttgacatc tgtaggatta tagtttttga taaaagcttg
      241 atctgacaga tctgcaatga gtcctccctc gatccactgc ttccacatcg gatcagcagc
      301 tcccttagac cattcctgcg gtgcgcctac gaagctgaat ttcagaggaa taatatctgc
      361 atcaccggtt gaacccgcat tcatacgcgt ttgcatcagt tgatcataag tggaatcagc
      421 aggaaccgtc gtatactcca cctgaacatc aggatacttc tcttcaaact ttttattaaa
      481 ttcctttata tagttattaa tattctcctg ctgccaatga ataattttta acgtgacctt
      541 tttattcccg ttctgcccag cttcgttacc tttaccgcaa gcggctaata ccacgattaa
      601 agcggttaca acaagtaaag aaaaacactt tttcagcatt gcaaaattcc ccctgtaatc
      661 ttagaataaa tgcactcact cttacgaaag cggtttagtt aattacagct actattatgt
      721 atcgaatagc ctgtatttgt aaatagcaat ttgtaaatta tcaaaaaatc attaactatc
      781 gttaaatcga acttcattat ccataatata ttaggattta tcctataata gcacggttga
      841 ctctcttcta tgaggtagca tagaatacga gtaatcatta attttagaat gcaaggtcaa
      901 atgaactaaa tcagtttagt tacggaggat tccatgaata taaaaacaat agctagcatg
      961 gcaggcgttt cagtagcaac ggtttcgaag atcataaaca attacacaga tatcagtgag
     1021 gaaacccggc agcgagtact caaaattatg gaggaaacag gctatagacc ttcctcctcg
     1081 gctaaaacgc ttgctaccaa aaaatctaat ctggtaggcg ttatattcgc tggcaagctg
     1141 aatgtcgatt ttagtcatcc tttttttgta gacatcatta atgttttcaa aaagcagatt
     1201 ggcttgctcg gttacgacct gctttttttt tcaaatgaga aatttctgga taatggagag
     1261 gactatttgg ctcgctcaaa atatttctca gtggacgggt gcattattat tgccggagac
     1321 gaagtggaga agagtgtttt tgatctcgat gccagcccta tcccctgcat cggtgttgat
     1381 atcgaattaa ccggagccag ctcctgctac atcatgtccg acaatcagaa gatttcaatg
     1441 aaagttgttg agcactttta catgaatgga taccgcgaaa tgggttttat aggcatagaa
     1501 cgcccctcct tggttattaa agagagagaa gaagctttta tctcatcact aaagcggttt
     1561 agccttgatg tcagaccgga atggatcgtg tatggcaagg actatgcagc agaggatgga
     1621 taccagatcg caaaggcgtg gatagagcaa gaaaatttac caagagctat ttttgcggct
     1681 accgacctgc ttgcctttgg tgccattcgt gctttcaagg agagcggctt gaaggtaccc
     1741 gagaatattg ccgtagtagg atgtgatgat attgaagcct gtcgttatac tgatcctcca
     1801 ctgacgactg taaaacaaga caagcaaaaa ataggtcgtc tggctgctat ggtgctgttt
     1861 gacctgatga ataaacaaat ggatacgaaa tgtattaaag tggagcccga actcgtcatt
     1921 cgcacctcct gcggagcccg gcaacattgg aaccctacaa gggttgaggg atagcacata
     1981 cctaaaaaag gtgactcctg tcgaattcag aagtcacctt tttgcagtta tataacaaga
     2041 gccctttcgt ttaagccatt atttgtaggc catcgtcgca ttcacagcct ttttccagcc
     2101 ttcatacagg ctgtcacgtg ttgcttcatc catcgtaggg gtaaaagaag tttccactct
     2161 cactcgctta cgaagttcat ctgtactctt ccagtatcct atcgccaacc ctgccagaca
     2221 cgcggcaccc agcgccgttg tctcatggat aactggccgt tccaccgtcg catccagaat
     2281 atcgctctgg aattgcatca ggaaattgtt caacacggct cctccatcca ctcgcagcat
     2341 cttcaccgta atacctgaat caatctccat ggctgtaagc acatccttgg tctgataagc
     2401 gagcgactcc agggtggcac ggataaaatg ctccttcgtg gtcccacgtg tcagaccaaa
     2461 catcgctcca cgtacctcgc tatcccagta ggggctgccc agcccgacaa aagcgggtac
     2521 aagatatact ccttctgtgg aggaaacacg ggccgcgtaa ggctcactgt cctttgcttc
     2581 acggaacatg cgcagcccat ctcgcagcca ctggatcgca gagcccgcaa caaacacact
     2641 cccttcaagt gcgtattgca ctttgccttc ctccagcccc caagcgatgg tcgtgatcag
     2701 accgtgcttg gattcaaccg gctgatctcc cgtattcatc aacatgaagc aacctgtacc
     2761 gtaagtgttt ttgatcattc ctttttcgta acaagcctga ccgaacaagg ctgcctgctg
     2821 gtcacccgct gcaccggcga tcggtacatt ctgaccaaaa aaatgataat ccacggtgtg
     2881 cgcatatacc tcggaagaag gccttacctc aggcaacatg attttcggaa ctcccagaat
     2941 atccagtagc tcttcatccc actttagctc ataaatattg tacatcagcg ttctggccgc
     3001 attggagtag tctgttacat gggcctttcc gccggatagt ttccagatta gccacgagtc
     3061 aatcgtacca aataataagt cacctcgttc cgctctttcc cgcgctcctt ctacatggtc
     3121 cagtatccac tttactttag tgcctgaaaa atacggatcg atcaatagcc ctgttttgct
     3181 gtgaaacaac tcctcatgcc cttgccgctt cagttcttcg caaatatccg aggtttggcg
     3241 tgattgccat acgagtacgt tatacacggg taatccggta tttttgtccc acacggccac
     3301 cgattctcgc tgattggtaa tgccgatggc agcaatttgt tttgctttta caccggattc
     3361 ggaaagacag gaggcaataa cgcccagaat agaactccag atttcattcg cattctgctc
     3421 tacccagccg gggtgaggaa aatattgcgg aaattcccgc tgggccgagt acaccacatc
     3481 tccttcgcta ttgaacaaaa tcgctcttga acttgtcgtt ccctggtcta gtgacaaaat
     3541 atattttccc atgttcatct ctccctgtgt aaatccatcg tttttacgct gtaagcttgt
     3601 gatccatttt atgattttta taaatacgac taatacggaa ggtaatcaag agtacaacca
     3661 cgataacccc taataaaatc cagaacgccg gagtcatact ccccttaaaa acggcctgat
     3721 aaaacggccc tgcgaaagat ccccccaata gcggtcctac aatgggcacc catgcatatt
     3781 tccagttgga tgctccctta ccgggtatcg gtagtaaata atgcatcaga cgcggcccaa
     3841 aatccctcgc tggattgatg gcatagcccg ttgtgcctcc aagggataaa ccgatactga
     3901 caaccaaaaa accaacaatt agcggtttaa ggccgtctgt aaacgaattg gcaccaaacg
     3961 acagtaaagc aagaacaaag ataaaagtac ctatcatttc actaagcacg ttaccaaacg
     4021 gatgatcaat agctggtcct gtcgcaaata cactgagttt ggctgctgtg tcctccgtct
     4081 ctttccagtg gggccaataa tgcaaaatga cgatcactgc acccgccatg gctccaagaa
     4141 cctgagccac aatataaccg ggaacatcct gccatggaaa actaccctga aatgccaacg
     4201 cgagtgtaac tgcgggattc aaatgcgctc cgctgatttg gcccaccgca tacaccccaa
     4261 tagctaccgc gagcccccac cccaatccga ccacaatcca gccggaagcg tgggcaaaag
     4321 actttttcag ggacacccct gcgcacactc cgccacctag ggcaataaga atcattgtcc
     4381 ctatgaattc ggctgcgtat ggcgacatac aaccaacctc ctcaatagat catccgattt
     4441 tgatcgtttt catcgcgcaa aaaaaaagaa aagccatcac aaaccaaccc tgtgctgtaa
     4501 catgggatgt ctgcgtggct ctcttgtctc cgtcacgatt attaacttaa atttgatatt
     4561 atataagcat gtaagcgatg tcaactgcgg atttacgtct tctgatatcc taaaataatc
     4621 gttgaccatg ttagattgcc cgatttatga tgtaaaaaaa tggctgaatg taaggatttc
     4681 aggatgaata cgacactccc aaacttgatg atgaagggaa gaatgttatg ctgaaatttc
     4741 tgcaaaaaat cggcaagtca ttaatgcttc cagtagctac attacccgcc gcagggattt
     4801 tgcaagggct ggctctcatt aattatgaaa cggatattcc gcttggccct ggagttggtg
     4861 gatttctgaa tcattatgtc actccttttc tgaatgaagg ggcgggtgct atctttggca
     4921 atctggcgct cattttctcc atcggtgttg ctattggtct ggcaggcgac gcggtagccg
     4981 cactttcggc agtcattgcc tatttggtgc tgacccgtat tttggcggcc gtaccgggta
     5041 tatttgcgta tattccagac gacgtcaagc tggacatggg cgtattgggc ggtattttta
     5101 tcggcggatg gtctgcttat ctgttcaaaa aatatcataa tattcaactt ccagattggc
     5161 tcggcttttt ttcgggcaaa cgttttgtcc ccatgattac agccttcacg accatgattt
     5221 tagccattct gctcggcatg gtctggagtc cgatacaaga tggcattgca gccttcggca
     5281 actggattgt tggctttggt ggaatcgggt caatggtgtt catgattgcc aatcgactac
     5341 tgatcccgct cggtctgcat catgtactga actcgatcgc atggtttcaa attggcaact
     5401 ataccaatgc tgcaggtgaa gttgttcatg gtgacctgac acgttttttc gcaggcgata
     5461 catcggcggg tatgttcatg tccggcttct tccccattat gatgttcgct ctgccagcgg
     5521 cggctcttgc attcatccat acggccaagc cggaaaaacg taaagctgtc gcttccatct
     5581 ttatcggttc tgcgctggcg tcgttcctga ccggtattac tgagcctctc gaattttctt
     5641 ttatgttcat tgcacctctg ctttacggca ttcatgctct gctaacaggt ctgagcggcc
     5701 tagtcgtata cctactggat gtcaaactcg gcttttcctt ttcggcagga ctcattgact
     5761 atctggtcaa tatgaagctc tccactcatc cattgcgaat gatcccgatc gggcttgtct
     5821 tcgccttcat ttattatttt ctgttccgct tcatcatcct caaattcaac ctaaagactc
     5881 ccgggcgcga agacgatgta gatgacaccc atctatttga ggctaacaaa tccatacccg
     5941 ttggaaaaag aagcgcctca tccggcaccc agtccagtca ggcaggccag gtcctaacct
     6001 atctcggcgg ttcagacaat atccaaagca ttgatgcctg catcacgcgg ttgcgtcttg
     6061 tcgtcaagga cgacaaagcg gttaacgatc aagctcttaa gcagctcgga gcgtcaggaa
     6121 ttatcaggct tgggaacggt accctacagg ttattttcgg tactcgatct gaagctctga
     6181 aagatgagat acaacgattg atgtcatgaa gctaatcccc tgccttaagc acgtgcgatc
     6241 ttcctataac agacgcacgt gctttttttt atggataaac gtttcaaatt ttttgttttt
     6301 ggttaaggca atgcacataa atgggtaaca gcttcatatg atggagctaa accatttaca
     6361 acttgttcag caggcagatt attcagacag caaggaggga aatgatgtga agacagtaca
     6421 atggcaatgg ctggtattat gtcttgcttt tctcactatg attagtggtt gtagtgggtc
     6481 cctatcctct aaaggtcaat catctgaagc taatttgtca aacagcaaaa agataacgct
     6541 tacattgtgg tactggaacc gttctattga cgatgaattg ctcgtccaag ccgaaaaaca
     6601 gtttcccaac attgaattaa aaactcaaaa aataggcggt gactttaaag ccaagctgaa
     6661 gacaacgctc gcagctcgtt ccggtgaacc ggacatcgta gctctgaacg actggatggt
     6721 ggagctattc ccgagtgcgg atcgttttta tgatctaaag gaactcggag cagaccgact
     6781 gaaggatcaa tatttggaat ggaaatggaa tcagggcatc actcctgatg gtaaaatgat
     6841 tgcatttccc atggatactg ggcctaccgc cctcttctat cgaagcgacc tgtttgaaca
     6901 ggcaggcttg ccaagtgatc ctgaacaggt cagtgcctcg attcgcacat gggatgatta
     6961 tatggcagcc ggagaacaac ttcggcagaa attcggaagc cattcatttt tggccgataa
     7021 tattgtaaac gtttacaatc aggtgctcgc tcaacatacg aacctgtact tcaagccgga
     7081 cggaagttat atcggcaatc aatctcctga catccacctg ggctggaaaa ccgctgtgga
     7141 tttccacagg aagcatctga tcgccaatgc agatggctgg actcctgaat ggaatgcttc
     7201 ggtcaataac ggcaaaatcg cctcgttcgt aggggcaatc tggatgaagc aagttctcac
     7261 agaagccgca ccggatacag cgggcaaatg gagagtcgcc cgtgctcctg gaggagacgg
     7321 caatctggga gggtctttca tctctatcct caaatctagc caacacccca aagaagcctt
     7381 tgaagttctg acctggctgc aaagcccgga acaccaactg gaagcctacc ataaaatcgg
     7441 cctgttccca tccactcccg gcgtctatga cgatccagtc atggagacac ccgagccttt
     7501 ctttggtggt caggccactg gcctcatttt tgccgcctcc gcacgtcagg tgaaaaatag
     7561 ctatttcggc gagcgctatc ctgtcatcca cggcattgtg acccgtcgtc ttgccaatgt
     7621 ggccaaacaa aatgccgatc ccgactcatt atggacggaa acaatgcaac gaattgaacg
     7681 ggaattacag cgttaaaaaa caaaacttca aaaaaggcgt gtggacaata tgctgagaga
     7741 aatctggaag caccgggccg tttatgctgc gatctcgcca ttttatttgc tgtttggcat
     7801 ctttggcttg tttccgattg gcttttcatt gtacctggcg tttcacaaat gggacgggat
     7861 cggagacatg acctacaacg gctggggcaa ctttcgttac cttgtgacag acaacgaatt
     7921 ttggcaggct gtaggtaata cgtttgtgat ctgggtgtac gccacgattc caatgctatt
     7981 tctagcactc attgttgcct ttctgcttta tgcccctttt gtgaaaatgt gcaccttatg
     8041 gcgagttgga ttcttcctgc ccaatgtgac atctattgtt gctgttgcca tcatctttgg
     8101 cgccttattt gccaacaatt ttggatttct caactacctt ttgcagctct tggggctacc
     8161 tatgatccaa tggctgaatg taccatgggg tatccaaatc gccatttctt ccatggtcgt
     8221 ctggagatgg atgggttaca acgccattat ctatctggct gggctccaga gtatcccaca
     8281 tgtgctgtat gaggccgcca aaatagacgg ggcaaccgga gcgcaagctt ttttccgcat
     8341 caccattccg atgctgcgcc cagtcatttt gtttacggtc attacgtcca ccatcggtgg
     8401 catgcagctg ttcaccgagc cacaggtcct ggtaggtaat gacggcggtg ccggggcaag
     8461 tggcatgacc atcgttttat acctgtaccg cgagtcgttc attaacaact attttggata
     8521 tggcgctgct gtcggatggg gcatgtttct catcattgct ctattctcca tcatcaattg
     8581 gaaactcgtt caaggtaaaa aataacgatg gaaggagctt taccacatga tacagacacg
     8641 tgcaaaatcc attgttttat atgccgggct gttggtaggt atcatcctgt cgatgtttcc
     8701 attttactgg ctaatcgtca tggcaacccg tacaacctca gacatctatc gttttccgcc
     8761 acaattgtgg ttcggcagcc acttcctgga taacatcacg agagtattgc agcagattga
     8821 ttttgccggc gcctttttga ataccctttt tgtagccagt tcgattaccc tattggtgct
     8881 gttttttgat tcactggccg gttttgcatt cgcaaagttt gattttccgg gcaaaaaggt
     8941 gttattcgtc attctgcttg caacaatgat ggtcccttca caactttcgc tcgtcccctc
     9001 atttgtcatg atggcttcct ttggatgggt aggtacgttc aaagcgctca tcatcccagg
     9061 tatggtaaat gctttcggca ttttctggat ccgccagtat gcagaagaat ctattcccaa
     9121 ggagctcctg gatgcggggc gtatggacgg gtgcagcttt tttcgactgt actggaatgt
     9181 agcactgccg attttacgcc ctgcgttcgc ttttctcggc gcatttacct ttataggagc
     9241 ttggaatgat tacttatggc cattaatcgt tttaacggat gagcgcaaat tcaccctcca
     9301 gattgcattg tcgcagttga acgggattta caatacggat tatgcgatgg tcattgctgg
     9361 caccctgctg gctgtacttc ctcttattat tttgtttctt ttcatcagcc gccaatttat
     9421 ttccgatctt gccgctggag cgatcaaaga ttagcttcac ttgattcccc ttttacttgc
     9481 tctaaagcgt catcgaaact ggacttaagc tctggagagg acttgcacaa ctatgagctc
     9541 cgtgcgattt tattaattgg aacgactgct ctaaatggaa ccctcaaata ggctacttcc
     9601 gaggctgggt ctacacacga ttgaacatgt actgtctacc tgttatccat atttccttgt
     9661 aaattagcct ccatagttat ctaacgatta ataaaaatcg cttccactca tttaacagag
     9721 tagaagcgat ttttcaaaaa ttaaataaac gtttctctaa taggtcaact taaagccata
     9781 tcatagtttg cactactatt catttgccta tcagagcgac atttacatgc acaattcgag
     9841 ccatgtccga agtcatgaag tatattatta gcaccggaag aacaaataca agataaagga
     9901 acaattccaa gggtatttgc cattaaaggc ttccttccaa atggatttac aattctcaat
     9961 ttataatcct ccttcgactc gttttgatta tagattggaa ttacaccaat gtaatatggt
    10021 ttaattcctc taataaatgt ggtttgtgtt ccaagatagt atgatagctt attaatgcat
    10081 gttccagcat atctaaagaa cgcctacaag ctattctctt tttttcgata ttaaacttat
    10141 cactatcgta acattcgacg taacaaaccg aacaaaggcg tatagcccaa catttggaac
    10201 actgagacaa actctcctta ccatagtcat ctatataacg atcgattaat acagattcgt
    10261 ctataccact ataaacgttt ccaactgaag gtgattttcc aatgcgctcg cataaatgaa
    10321 agtctccatt taccgttaca taaattcttc ttgaggcagg tgaacagcag ccgtttaagc
    10381 aatagtccgg gtaaggagtt tcagttaaaa tcctatcatg tattattgag aattgtttgt
    10441 gtaaaaaatc gattgtaaag ggagtatttt ttgatataga agtattattt aacattagat
    10501 caattgtcca gttccctaca gggttatcat aacaatgcat agagcttttt tcagtaatcg
    10561 ttttttctat gtcagacgag tgtctcacat aagaaatatt tttagtaata tccttaggta
    10621 cccacgaaag agaattgaag aaattttgaa tttttttcat aactacatca ttagctggtc
    10681 taggtgttac catgcttagc gatataagag aattactctt ttctccataa gcattaatta
    10741 gatgtttaag accattaatt gccttgtcat acgtgccctc accattttta aatcccctcc
    10801 tacaatcatg tatttccttt ggaccgtcaa tactacaaac tactccaaag ttaggaactg
    10861 tagatagata ttctgcgatt tcagcagtca ttaaggttaa gtttgttgtc attgaaaatg
    10921 ttaaatcttt atcagcacca ttttttaaag tatagtctac acaatgcttt aataatttaa
    10981 attctattaa tggctccccg ccataaaaag ttaccgccac ttttttacct gagtttttca
    11041 gagtataatc gattgctaac tctgctactt gccaggacat gtgcctgcgt ccaaattccc
    11101 tgaagtctat gttccctgaa tgatatatac aatagtggca tgccatatta cattgttcgg
    11161 tcaactccag agtaacctgt tctagatgac ttcttgcatt ttctaaaacc tcatcttttg
    11221 atagtgcaaa ggataaaaga ggaggtgctt ggaataaatg ctgttcctgc gcaacatgta
    11281 ttaagtcaat tagaatagtc aatgtatcat cattaacttt ggtagttttt attacctctt
    11341 cgatatctcc gtacacttgt aagttattta gaaatacata ctctatttca gtgcattcca
    11401 taactttgcc tgtgcccaca tcatacaaat aggatttatt ctttgtctga aacaacttaa
    11461 acaatcgtga gtaattccca tactgttttt tgatgtttct aaagaactcc ataactgtgg
    11521 aatccaatat catcacgttc ctcttgggtt tcaatattca aaatatggtc acatgctgct
    11581 aatagtctct ggtcatgtga tactacaatt gttatccttc ttgacttttg cttggtcaat
    11641 atttctataa gtccacttac actctttgaa tctaaggctg atgtgggctc atcaagaatc
    11701 gttaagaaag aatctttact taatgcacga atcaaagcta atttttgctt ttcaccacca
    11761 gaaaagttgc ttccattttc atttattagt atattttcaa ggttagcttt tgttattatc
    11821 tcttcaagcc caaaagctgt tataagctca tcttgattac tggcaatctc ttttgaaaaa
    11881 gtaattccaa atttcaaata ttcctttatt ggtagattta aaaactccgg attctgttct
    11941 acataagaaa ttctataacg cctcatatca agcatatcta tatctttgat ggagcaatta
    12001 ttaaaagcta tttctcctgt gtaaagatca ctataaagac ctatcagagt attaagtaat
    12061 gttgttttgc ctgaaccatt gtgaccacaa atcccgtaaa ttcccccctt aaaaaaatca
    12121 taagaaaagt ctctaaatac gctttcctcg gaatatttaa cacctaattg tttaatactt
    12181 attttctcta aatcttcaag tgttgtacta ccataaatat cattttcaga gttcataacg
    12241 tcatttaacc gttctatcga tactttcgtc tcttggtatg aacttgctaa gcttaataaa
    12301 tatgaagttg acgagatgat cattgaaagg tacgtgttaa ttatggtgaa ctgccctata
    12361 ctcatttggc caattacaac tttatgacct ccaattccga ttacaaatat atagcagatg
    12421 atcaatataa attgatttag attggagaaa atataattag tttttacttg tgaagtcgca
    12481 actctaaata atgaattaaa tgctttattt agccgctcat tcatttcatt aaagagtaca
    12541 ttcttcttta taaaaaccaa tttgttaatt tgttcgactt ttttagagta gtattcattt
    12601 gcttcttttt tgtatttcag atttgcttta tacaattttt ttctaaaaac cacatatgta
    12661 aatatataac aaggaataag cgagaaaatt ataacgcata gtagtacatc agcttttaaa
    12721 acaataatac cactgataat tattgtgatt acttgcaata ctaagttgga aatattattt
    12781 gaaaaaaagt caactactgt ggatgaatca ttattaattt ggtcaactaa gtatgcatta
    12841 tccttatctt tgaagaccga cagtttagtt ttgaatatct tttgatagat atcattgcag
    12901 atttcgtata ataataaatt attcaatttc gtagagaaaa gggcagttaa atattgtatg
    12961 agaatgttta ctatatttat aatccccagt aacagtacaa aatataaaat gatacttata
    13021 ttactttttg atactaaata atcaatatat atgcctgtga tgtaaggaac aataattcct
    13081 ataatccaca atactgaagt aacaacaatg taaaaaaata catacttgcg ggtttttgaa
    13141 aggtattttt tcaagtattc taggactatc atattcatca cctatgtttc atattaggta
    13201 aatcttagcg agatgctaaa aacagcatct cgctaagtaa tgttacttct cttaagctac
    13261 atcttgtagg aacaagaaag agtgcagcca cttgaaccgt ggaaaggaca atgtgcactt
    13321 acttgtacag cactttttac caatacgtcc atagtttttc cctccttaaa atttaattta
    13381 tataaataac atacagttta aaaactatat gctacttatc acttttgagc tgcaatagaa
    13441 aatgcactgt tttcaagcgt gatatttatc tttgctttac ctgcaccatt tatatagtta
    13501 tatgttaagt ttggtctaaa caatggccat cccgcaggaa cacttaatgc acttgcagtc
    13561 gtcttaactg taactgtgta atccgaagct cctttactaa aagttaagga acctgaacct
    13621 tttgtattgt cataactaat ggcttttgag tatcctacag gcacccgaac tgacattgag
    13681 gaaccatcta cacctgtgat atcaagatta gtatttagct ctggaagtga aactccagac
    13741 tttgtacttt ctaccgttat tttttcataa cttttatcag gaattaaaat attaactctg
    13801 tcggaaatgc cgttagctga gcctttcccc tttactgtga tgtaaattgt agatccactt
    13861 aatgtagaag tgacagtata caaggatttg ttatactcat aactaaaatc acttgctgaa
    13921 gtttttgtaa cggtgacatt acaatttata gccgttagat tgatattctt aacatcattt
    13981 gaagctgcat tacttgaagc acctaatggc atccccataa gtaagaaacc acataaaaca
    14041 atacacattt tttttagcat taacatgatt cagaaacctc cttcttattt tccgttaatt
    14101 gtccagccag taatactttc gtgcactcgg taatatactc ctgcaaatta taacgatatt
    14161 gctcacatat gttaaagtct gccattctat tatgaggaca tcctcctaaa cacacaggta
    14221 agtacttaca gtctgaacat ttttcatctt cagtaggatc atataataaa taacaaccaa
    14281 gaagctcagt attccatttc actgatgtat cttcatttat atttccaaca cactgctcaa
    14341 taattccaat atcgctccaa catttatata aatgaccaag aggatcaata acgaaactat
    14401 tatatttgtc cgcagaacaa taattacctt taggtgcagg ataaatataa ctaattggga
    14461 tatcattttc cgacataaat tttaaattaa attttgaata catctcgtct gtcaagcact
    14521 tagttccctc atactttcca ttcgtcggcg taactaatcc tagataaggt attacatttt
    14581 ccaataaaga attttccttt aagaatccta cgatttcatg taaattcaac cagttgtctt
    14641 ggtcagtatt tattctcata aatatcttaa tcatcccttt aatttgcttg aggttattca
    14701 ttatgacatc aaatgtccct cttccactta ctaaagggcg tctaagatca tgtacttctt
    14761 taggaccgtc aacagtgact tgaatatcat ttactccaca tgatattaac gtttgaactt
    14821 tttctttatt taaaagatag ccgtttgtaa tgacactggc cgtatattgt atattgtttt
    14881 ctttacatat ttccaaaaaa tcttccgata tcctaactat ctgcttcatt gcaatcaagg
    14941 gttcaccgcc ataccatgta acattaagag tgtcaagttt actagcattt gctttaacaa
    15001 aattgactat actttgagct gtttcttcac tcatagtttt gttatgatat tggtctttct
    15061 caaaacagta tacacatcga aaattgcagg ccattgtagg ggcaattgtt agcattaaat
    15121 tagaagattc aaaccgattt tttaagaggt ttacctttac atatgctttt tcattcatat
    15181 tatcttctac gatatagcca cattcgataa gatttttaag ataagtatca ttatttattg
    15241 ccaatccatt gtttgtaagt tcacaaaact gtttatagta ctccggttca agaactgcca
    15301 atgcacctgt tcgagaatta taaagtaccg ttttatcggt attttcaata atgtcattaa
    15361 aaataaagtt atattgcgaa gctttcattt tagccctcct tagaatggat gcggtcccta
    15421 tgtaattatg aatcgattaa ctagtgacaa aattcacata agttttaaaa ataagatgta
    15481 cgctcattct gagttgtaat agcattctcg cagtgcacac tagccaccaa gaatagatgt
    15541 ccatcatccg aaaccggact gaatttaaaa gccatcctac acctttatag tttattcata
    15601 tactttattc tctctggaca atatctatac tagatagctt ttccttctcg gcttttaatg
    15661 tagcataagg caaaaagaaa aaataagctt gtatcctgaa atgcaaaaaa gtccatctca
    15721 acgaccaaat atgtcagctt catgtgagat taatattttt gttacctatt ctaagcaata
    15781 aagaagaacg tatccattcc ctcgcctggg ctacgtccta tccacagtat aagtatgcat
    15841 ttgaactttt actaacaaaa attccataac ctgatggtaa tttttttcat atgtaaaaca
    15901 tcacttcgaa tagacttttt ttacaatata ctggatttat ataacatatt tgaggtggtc
    15961 tatttgtttc aagttgctgt ttgtgacgat gatcccgcaa tgcataaaat tttacaacac
    16021 tttttcatgt gtatgtcagt aagtgaatcc tttgatttta atctacaatt ctttttatct
    16081 ggggaagatc taatcaaatc ttacagttca caagagcgat acccctttca tattatcttg
    16141 ttagatattg aaatgaggga attatcggga attgaaactg caaaacttat tcgccttttt
    16201 cctgaccgag aagttcaaat catatttcta actaactatc cagaatacat gctagaaagt
    16261 tttgaagtac aagcatttca atatttactt aaacccctta cttataaact ctttgtagaa
    16321 aaaataaata aactatgtca ttatatgcgt tcttcagtat cccactttct gtctgtgaaa
    16381 aataaaactg agcatcttgt attgagacac tctgagatca tagccatctc aaaaggtgaa
    16441 aacaattaca tccataatga actttgtatt gcaacggatt cacacaacta ttttatttct
    16501 ggaacgttga aagcggttta tgaacaatta aaatatccgt ttgtgtttat acataggtca
    16561 ataattgtga atttagttca tatacgtaag ttttcagcta cttctgttat tatgtcaaac
    16621 gaacaagaat tccctgtagg tcgttctcac gctaaatcac ttcgtgaggc gtatgctcgt
    16681 tttataattt ctcgttttca ggaagggtga gttttttgaa tcattgcgtt tacattaatg
    16741 tcacctcgtt ttctaattac tctttatttt tatttagcac aacaaagcaa agtcattttt
    16801 ccaatccaat agttaacctt tttttacttt tcgcctcttt acacttcata cttattacag
    16861 tactagtagt tcattatttt aaaaaaggaa gaaaatacaa gatagggatt gtgtattatt
    16921 ttgtaatatt aataggaaca tcgtttaact tgctcataca ttacggttta ttttctttta
    16981 tgaaacataa tttattcttt ataatgtcaa tcatcagtat tcttggaatg aacgtgatta
    17041 atgtctttct aacggacaag ttgatagaaa agtcaaacct ctcatgcttt tttcaaaagc
    17101 aaatgctgat gcaagaaaaa cgttataaag aaacaattcg atctcttagt gatatcaaac
    17161 gaagtattca tgatttcaaa aaacagttaa tttttgtccg tgcttgttta caagaacaga
    17221 ggacggaaga gggtgttaat cacatcaacc aaactctaaa aaatatagac tcaccaaaac
    17281 ttcatataac aacaggacat ctcgttattg atgctttagt aaatcatact ttcagcatcg
    17341 ctaataaaag tgggatagct ttcttccatc aaatccatat taacccggca aatattagta
    17401 ttggaagtca tgatctatgt attgtcttag gtaatgtttt cgataatgct attgaagctg
    17461 taatgcagct tcctagaaag aaagagcatt caattcattt ggaaattttc accgataata
    17521 ttgccctatg gatttatgtt cgcaattcaa aaagtaatta tctcaataca gcattctcaa
    17581 ccaaaacata caatccccct ttaaaaaaac atgggtatgg attacttaac atccagcaag
    17641 tgataaagaa atatggtggt tatttaaata caactattac ggattcgcat tttcaaatta
    17701 cgattatgct cccatgtaat aactcttagg tttgtaaacg ttatggatta agagatattc
    17761 agaataaata aaatgtcggt aatcaccagt cttataacct aaaaaaagga gtaccctcaa
    17821 gcctgtgatg gctgaggata ctccctttta gtatttatga atttaccgtt tgtccctttt
    17881 cttctacttg gatagccgcc cctacattgg caccagcaag aatacccttg ttcttattag
    17941 gatacaaaga attcatataa gtccgggttt ctgcaacaac aattcccgac aagccgagca
    18001 gtgcaatcag gttcggaaaa gccatcatgg cgttaaaaat atctgccagc agccagatgg
    18061 catcgagctt gatgaacgcg cctccggcaa ccagtacgat gaacagataa cggtatggtt
    18121 taatccactt gaccccaagc aaatattcaa cacagcgttc cccgtagtag ttccagccaa
    18181 gtatcgttgt gaacgcaaat aaaataaggc taatcgtcac gagctctgct ccagccggaa
    18241 aggcactgga aaacgcatgc tgagtcatca gacctccatc atcatttcca ctccatattc
    18301 ccgtaaccag caatgtaaat cctgtcaaat tacaaataat catcgtatcg ataaaaacgc
    18361 ccgtcatgga tattagccct tgttctgcgg gccatttcgt cttagctgct gctgctgcga
    18421 ttggcgcact tcccaaacca gcttcatttg caaagatccc tctggcaact ccgcttcgca
    18481 tcgccagcat aatcgtggct ccggcaaatc cacccgtcgc agatgttgtc gagaaagccc
    18541 cttgtaatac tagtgcgatc gcatgaggaa gctctcctgc aaacttaatg agtacgatta
    18601 aacaaaccac gatatagagc cccgacatga atggaacaat ctttgtggat accttggcga
    18661 tacttttgag tcctccaatc gtaacaacag ccgtcaacac ggaaataatg attgctgtaa
    18721 ctactgttgg cacgccaaag ctactttccg tagaagaaac gatagccttt acttgcggaa
    18781 aagtaccgat tccaaatagt gctacaagaa taccagaaaa ggcaaacaac atcgccagcg
    18841 gcttgaaacg gcggccaagc ccattttcaa tataatacat cggtccaccc gaaaattgtc
    18901 cgttccggtc tttaacacgg tatttaacgg ataatagccc ttccgcatat ttggttgcca
    18961 tcccgaaaaa agctgcaacc agcatccaga ataatgaacc gggcccaccc agtttgatcg
    19021 ctgttgcgac accgacgata cttcccgtac ctacagtagc tgcaagtgcc gtactcaatg
    19081 ctccaaagct actgacatcc ccgctgcctt cgtccggcgc tttaccaatt agcttgagcg
    19141 ctaagggcaa tcgaataatc tgaagcatct tcagacggat cgttagccac aacccagtgc
    19201 ccatgacgag aattagaagc ggcgctcccc acatccaact gtcaatcgtt tctaacacat
    19261 gtaccaaatt catttcaacc cgctccttca gcatagtaga aaacaaaaaa gagtcaaatc
    19321 tgttgattcg actcttggag aggttaaagg cacgaaaaaa tacaaccatc ttgtgcagga
    19381 tttcacctct aaaagcttat aaaaagccta gggctatccc tgtcacaggt tattcgcgtc
    19441 tctgtccttt tgcctgagag tttaagcaga tgtgatctgc ggtgcacctt cggcgcccaa
    19501 ttaagggtct ctccagagtt ctgtccgttt acggtccctg ctcgttgctg taaatcagcc
    19561 taagcacctg agagttttgc cccttcggtt ggaactttca ttccatctcc cgcaaacatc
    19621 aaccagacat atgaaatttt tattcattat acagaaaaat ttcagcttat tacaagtgaa
    19681 aaatttgtga agccctctga aagaatcaat agagtgtcta tacaaaaagc gggtacagca
    19741 gattgcatcc tgaggatttt ctctgctgta cccgccaaaa cgatatggaa ttacaattct
    19801 tcaccgttgg ttgctatcac atttttatac cagttaaatg agtccttttt ggagcgttga
    19861 agcgttccgt taccgtcatc atccagatca acgtaaataa atccgtagcg cttggacatt
    19921 tcggacgtag acatgctcac aaggtcgata ggtccccaac tggtgtaacc aatcagatca
    19981 acaccgtcag caatcgcttc cttcatttgg gcaatatgct gacgcaagta atcaatgcga
    20041 tacgtgtcat gcacagagcc gtcttcttct accttatcat acgcacccag gccattttcc
    20101 acgatgaaca gtggcttttg atagcgatca taaaacgtat tcagtgtaac acgcaggccg
    20161 atcggatcga tctgccatcc ccagtcggaa gactgcagat acggattttt cacaccgcct
    20221 atcaggttcc ctgctgcctt ttcgccttct ggccctgccg atacggtcaa ggtcatatag
    20281 taactaaatg agataaaatc gaccgtgtta tttttcaaaa tttcggcatc gccggattct
    20341 gtctggatca caatattatt ttcttcaaaa tagcggttca tatagttggg atattcccca
    20401 cgagcatgca catccgtaaa gaacaggttc atttgatttt catgctgtgc tttcaggata
    20461 tcttctgggt tacacgtatg tgggtagctt tcaatgcggg ccagcataca gccgatctga
    20521 gcgcccggaa tgatctcatg tccccgtttg gtcgccaatg cacttgctac aaattgatgg
    20581 tgcaatgctt gatatatcgc ttgttgcttg ttttctacac ggtcaataac cacaccgccg
    20641 cctgtaaacg ggctcatagt catgacatta atttcgttaa aggtcagcca gtattttact
    20701 ttatccttat agcgtgtaaa taccgtttcg gcatatttta cgtaatgatc cacgacttcg
    20761 cgtcccaacc agccattata tttctgtgtc aaacctagcg gtgtttcata atgcgacagt
    20821 gttaccaaag gctcaatacc atacttgcgc agctcatcga atacattgtc gtagaattgc
    20881 aatcccgctt cattcggctc ggcatcatat ccattcggga aaatccgcga ccagtggatg
    20941 gacatccgga atactttaaa gcccatttct gcaaacaagg caatatcttc tttgtagtgg
    21001 tggtaaaagt ccacaccttc acgctttgga aaacgggcgt ttaccttccc tgccaagatg
    21061 tcctccagtc gttcggacga aatttctata gcatgatcgt tcttacgttc tgatttaggt
    21121 acataggcta tcatgtctgc gctggataga ccttttccat ctacgtcaaa agcaccttcc
    21181 aattggttgg ctgcagttgc cccgccccag agaaagtttt tcgggaatcc ttttagcgtc
    21241 ttcgtcatgg tatgaaaacc tctttcctta atttaatgtt ttcactttag tcagtaaccc
    21301 gtcaggtgct gcaatgcgaa tccataacta acggtaaccg ttctcctttg aaatgcatcg
    21361 acagatgctt taaaatagac gtaatgccct cataaagcat cctaattgtt gtaacgcgtt
    21421 tcatgtcaag tatttttttc tcaagtgagg agaagcatca tgtcgaatct tgatcaaatt
    21481 gcaaaactgg cgggcttttc caaagctacg gtatccagag tgttaaatca gtccccccat
    21541 gtaagccaag aaaccagagc taaaatttta aaaataatgc aggaattgga ttatgttcct
    21601 aatcggaatg cgatctctct atccaagggt cagacgcttc agattggtat catcacttca
    21661 actatcaatg aaattgtgct ggcatttctg gacagctttg tggaaatcgc aggccaatat
    21721 gaattccaaa ccattattta tacttcggga gaagacaaaa agaaagagct tcaagctttc
    21781 gaggatttaa aaagaaaaag agtcgatgcg ctggtcatca tttcctgcgt gaatgacact
    21841 gattttttga gtacctattg taaatatgga ccgatcgtgg catggcaacg tatggagcat
    21901 accgatattc gctccgtcgc tatggatcaa tatgaaggat acatgttagc attaaaacat
    21961 ttgatacaaa aaggctatac acgtatagcc aatgcttttg gtcgtccgag cagcatcaat
    22021 actcacagca gacaacgagc ctatgagcag atcatgagtg aacacaatct gccggtgctg
    22081 ccacactgga actattcttc tatttataac attcgtgatg gcgaacaggt cgtgcgcaat
    22141 ttgttacagc atcgtgagga atttccggag gctatcttgt gtgctaacga ttatgtagca
    22201 gtgggcattc tctgcgaagc gcgcagacaa ttgctgaggg taccggaaga cttggcgatt
    22261 gttgggtttg ataacacgga gctggcgcac accatgggca ttacaacggt tcaaaatccc
    22321 attatggctc aggcacaaaa tgcttttttc atgctttccc ctcagctgat tggacgccaa
    22381 atggagcttc attcgctaga atacagcctc atagagcgta cgactactta agggcacaat
    22441 tgacttgcaa attaggcaaa tgggccttga tatgaaatat tttttgtcga aagagaataa
    22501 aatatgttga aatcgctttt ttttgtgcta caatagcact atatcgaagg attgtgaccg
    22561 gtgatgcggg caatgcctga gttcaattga gtgctattgc taacaatagt gttgaattgt
    22621 gcttgggcat tttttattgg taaaggatgg gagggggaac ttcaatgatt attgagaagg
    22681 tgctcaataa caacgtcctg ttgactaaaa acgataaagg caaagaggtc atcgtcatgg
    22741 gaagaggtat ttccttcaaa aaggtggctg gcgaccaagt cgatgatcat aaaatagata
    22801 agattttcat gttaaatgaa aacgagttca cggccagact aactgagctg ctaaacgata
    22861 ttcctgtgtc tcatctggag gtcgtgaatg aaatcgtgac ccatgcaacc gaagtgctgg
    22921 atacggagtt aagtgataac atttatttaa cattgaccga ccatattcat tttgccatac
    22981 agcgggaaga aaaaggattg gcactcaaaa acgcgatgct gtatgaaatt aaacgctttt
    23041 acaaaaaaga atttgcagtt ggactggatg ctctacaaaa aattgaaaat acgctcggtg
    23101 taaaattggg cgaagacgaa gcgggattta tcgcattgca tatggtgaat gcacggatcg
    23161 atggtaacga gatgaaggct acactaaaaa tgactgagat tgtccaacac atattgaata
    23221 ttattacgta tcattacggg attgtgctgg atgagtcttc ttttagctat tcgagatttt
    23281 tgacccattt gcaatatttt gcaatgcgag tgattcgcaa agaggttatt cacagtggtg
    23341 aagaattttt gtacaaccag gtaaagcaaa catataccga ggcttttgct tgtgcccaaa
    23401 aaattaatga gtatctggaa aaaacatatg atcaatattt aagcaaagat gagtatgtat
    23461 atctaacgat tcacattcat cgggtaactg agcgtaataa catatcaggc taaaaacttt
    23521 atatcctcat cgttcatgga ttgtgactgg taaggcaggc aaaacctaaa ctgatggtga
    23581 aatcgacgtt cccttatagg aggagtgcgc agttttcacc acgagtttag gtttttcttg
    23641 tttacaaggt taaaaaagat gcacgccggc gcatctcagc aacaaatgta aacggtaaat
    23701 cctatcagta gcaagaataa cacttaagga gttctgaaca tgagtgataa agagctatcc
    23761 aaaaaaatag tgactctcgt tggcggcgaa gagaatgtca attcggtatt ccattgcgct
    23821 acacgcttga gatttaaatt aaaagatcgc acaaaagcgg acaaagctgc actggaagca
    23881 acacctggtg tcattacagt ggtggaaagc agcggccagt tccaagtggt catcggtaac
    23941 aatgtaggtc aggtctttga gcatatgatg gcagaaacaa atctgcagga tgcagataat
    24001 ccaaatgcaa aaaaagaaga atcttccgaa aaaacgaatt ttcttggcaa agcggtcgat
    24061 atcatttcca gcattttctc acctctcttg ggtgctcttg ccggagctgg tttgctcaaa
    24121 gggattatgg ccttaattgc gtcgctccat tggattaata ctgcaagcgg tacgtatctc
    24181 attctgaacg ccgcttcgga cagcgtgttt tatttcttgc ctatattcct agctattaca
    24241 tcgtcccgta aatttaagac gaatgccttt gtatcggtcg cagttgctgg agccctcgtc
    24301 tacccggatg ttattgctgc ggtggaccat ccggcaaaac tggcttttct cggaattcca
    24361 atcattctga ttaaatatag ttctagcgta atcccaatta ttctcgcggt atgggtacag
    24421 tcctatgtgg aacgttggtt taattccttt gttcatcaat cggttaaaaa cattatcgtc
    24481 cctatgctat cactgctagt tgttgttccg ttgacgtttt tggcctttgg tccagtcggt
    24541 aacctgatca gccaaggctt ggcgaacggt tttacatggg tgtacaattt aagcccattg
    24601 attgccggag ctgttgctgg ggcattctgg caagtatttg ttattttcgg cgtacactgg
    24661 ggcttcgttc ctattatgct gtccaatatt caaacattgg gttatgacac gatgcttcca
    24721 atgcttacag cagccgtact ttctcaagcg ggtgcaacac tgggggtatt cctgaaatca
    24781 cgaaatactc aaatgaaagc tttggctggt tcttctacac tggcagctgt attcgggatt
    24841 actgaaccta cgatttatgg tgtaactttg aaattgaaaa agcctttcat ttacgcttgt
    24901 atttctggtg gtatcggtgg cgctattatc gcttccggcg gagcaactgc aaaatccttc
    24961 tccctgccta gtttactggc gttgccaact tattttggag ctgggttctt gtgggttgtt
    25021 atcggcttac tcgttgcctt tgtacttgca gttgtattgg ttatgatttt gggctttgat
    25081 gatccaaaag aagaagctgc aaaaacagaa acagcacccg taaaaaaaga agtagccatc
    25141 gaaaaggaaa tcctcgtaag tccgctgcaa ggtaaagtgc tgtcattgga acaatcttct
    25201 gatgttgctt ttgcttcagg cgctatggga aaaggaatct tgatcgatcc tacagagggt
    25261 gtgctgactt ctccggttaa cggaacgatt acaacagtat tcccgaccgg acatgccatc
    25321 ggtattactt ccaatgacgg agcagaaatt ttgattcacg ttggtgttaa tacagtgaag
    25381 ctgaaagg
//
