LOCUS       NZ_JAHVOC010000011     21746 bp    DNA     linear   CON 04-NOV-2023
DEFINITION  Bacillus sp. XT-2 Scaffold11, whole genome shotgun sequence.
ACCESSION   NZ_JAHVOC010000011
VERSION     NZ_JAHVOC010000011.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus sp. XT-2
  ORGANISM  Bacillus sp. XT-2
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 89192)
  AUTHORS   Wang,X.
  TITLE     Characterization of the facultative-halophilic Bacillus halotolerant
            XT-2 producing multiple lipopeptide biosurfactants and its potential
            for Enhanced Oil Recovery and bioremediation
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 89192)
  AUTHORS   Wang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUL-2021) State Key Laboratory of Microbial Resources
            & CAS Key Laboratory of Microbial Physiological and Metabolic
            Engineering, Institute of Microbiology, Chinese Academy of Sciences,
            1-3 Beichen West Road, Beijing, Beijing 100101, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-MAY-2021
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: GCF_004006435.1
            Genome Coverage                   :: 95.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/04/2023 05:26:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,802
            CDSs (total)                      :: 4,698
            Genes (coding)                    :: 4,533
            CDSs (with protein)               :: 4,533
            Genes (RNA)                       :: 104
            rRNAs                             :: 8, 8, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 7, 8 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 165
            CDSs (without protein)            :: 165
            Pseudo Genes (ambiguous residues) :: 0 of 165
            Pseudo Genes (frameshifted)       :: 95 of 165
            Pseudo Genes (incomplete)         :: 92 of 165
            Pseudo Genes (internal stop)      :: 27 of 165
            Pseudo Genes (multiple problems)  :: 43 of 165
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:21:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 21746
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHVOC010000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21746
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     gene            <1..138
                     /locus_tag="KXD37_RS21865"
                     /old_locus_tag="KXD37_21625"
     CDS             <1..138
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611387.1"
                     /locus_tag="KXD37_RS21865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21625"
                     /product="IS3 family transposase"
                     /protein_id="WP_142396760.1"
                     /transl_table=11
                     /translation="LNSINRTTTAIVERTVKEYIYYYNNIRIQTKLNSQSPISYRQSAV
                     "
     cand_cluster    1..21746
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21746
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[9148:11746](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9149..11746
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(198..1061)
                     /locus_tag="KXD37_RS21870"
                     /old_locus_tag="KXD37_21630"
     CDS             complement(198..1061)
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010333403.1"
                     /locus_tag="KXD37_RS21870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21630"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_254518114.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 1.6e-09, bitscore:
                     29.8, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAVIGLGNMGQPIARNVLQAGHRLTVYNRTKEKTEEFASQGAQ
                     VAETPRQAAETADIVVTMLSDDNSVSNVTFGKDGLIEGLSENGIHISMSTISVEFSEKL
                     AAAHAEKGQSFLAAPVLGRPDAAAKAALRIIAAGPAEAKKTAKPLLESLSQQVFDVGEE
                     SKTANAAKISINFLLVSMLEALSESFLMMEKYGLEQKQFLEIANALFGSPVYQNYGTIM
                     AEQTFEPAGFKMSLGLKDTNLALAAAGQVSANLPLAELAKGHFESGIEKGLGNLDWAAL
                     IKCIEK"
     gene            complement(1161..2120)
                     /gene="corA"
                     /locus_tag="KXD37_RS21875"
                     /old_locus_tag="KXD37_21635"
     CDS             complement(1161..2120)
                     /GO_function="GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="corA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388681.1"
                     /locus_tag="KXD37_RS21875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21635"
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="WP_059291643.1"
                     /transl_table=11
                     /translation="MINITAITTQHQLLKNIPIERVEQPDIAWYWVDFYGPEETETALL
                     RDFFHFHPLAIEDCFQHMQRPKLDHYDGYRFYVLHALNQETLETEEVDIFQGETFVVTF
                     HLHETPGIAKVRERLYASPDMFKKGPGHISYMIMDQLVDEYFPLVYKIEDRLNEIEDSR
                     SHKTYGTLMSEVFELRTDLLHLRRTIIPMRDLLYRILSLDHVKEQRETKAYFSDIYDHL
                     LKLSEIVESNRDMTSDLRDSYVTLNSNRMNAIMMTLTIVSTIFIPLTFIAGVYGMNFDN
                     MPELHWKYGYFAVLGLMAALVAGMLIWFVHKGWFNIFK"
     misc_feature    2155..2169
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.07"
                     /tool="antismash"
     gene            2239..3102
                     /locus_tag="KXD37_RS21880"
                     /old_locus_tag="KXD37_21640"
     CDS             2239..3102
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388682.1"
                     /locus_tag="KXD37_RS21880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21640"
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="WP_106021626.1"
                     /transl_table=11
                     /translation="MWKEKVSVTPPYHFDRVLDRLALDPLNAVDLKARDIRVPIRNKAG
                     DVCIVKVQALGHADEPEFLVSGETEQEDMMKEIKRIFQWEHDLQHVLDHFSKTNLSAIF
                     EEHAGTPLVLDYSVYNCIMKCIVHQQLNLSFAYTLTERFVQTFGEQKDGVWCYPKPETI
                     AALDYQDLRELQFSMRKAEYAIDTSRMIAEGTLDLSELPQLTDEDIMKKLIKIRGIGPW
                     TVQNVLMFGLGRPNLFPLADIGLQNAIKRHFNLDDKPAKDVMLAMSKEWEPYLSYASLY
                     LWRSIE"
     misc_feature    2279..2294
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.09"
                     /tool="antismash"
     gene            3216..4616
                     /gene="rlmD"
                     /locus_tag="KXD37_RS21885"
                     /old_locus_tag="KXD37_21645"
     CDS             3216..4616
                     /EC_number="2.1.1.190"
                     /GO_function="GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rlmD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388683.1"
                     /locus_tag="KXD37_RS21885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21645"
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="WP_106022409.1"
                     /transl_table=11
                     /translation="MNQQNKKALVELKVGQTFPLTIKRLGINGEGVGYFKKKVVFVPGA
                     LPGEEVVVQATKVQPKFSEGRIKKIRKASEHRVAPPCPVYEQCGGCQLQHLAYSQQLRE
                     KRDIVIQSLERHTKFKVENMDIRETVGMDNPWNYRNKSQFQIGRSQSGSIIAGLYGLDS
                     HDIVPIKDCVVQHPATNKTTGIVRRILEDFNVSVYNERKRKGDVRTIVTRVGFETGEVQ
                     VVLVTAKETLPHKEEIVKAIQKRLPEVKSIIQNVNGAKTSVIFGEKSKPLAGHTVIQEV
                     LGDVSFELSARAFFQLNPEQTVKLYDEVKKAAQLTGKEKVVDAYCGVGTIGMWVADGAK
                     EVRGMDVIKESIDDAKKNAKKHGMTNATYVTGTAEHWLPKWTKEGFRPDVVIVDPPRTG
                     CDGTFLDTIKKVKPKRFVYVSCNPSTLAKDLQALSKDYRVEYIQPVDMFPQTAHVEAVA
                     KLVLKSSH"
     gene            complement(5531..6928)
                     /locus_tag="KXD37_RS21890"
                     /old_locus_tag="KXD37_21650"
     CDS             complement(5531..6928)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469907.1"
                     /locus_tag="KXD37_RS21890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21650"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_106022408.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.7e-45, bitscore:
                     148.1, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLRRISMVFIFVIVSSLQPISSHAEESNYDESIIINLDSKVSE
                     STINKVQEKYSNIETNYIKELDLLVIDNIKPSQFSAIKDIAKEKLDAKEIIEDKDISLP
                     DKSKQIPDKVAFSSQFTEDNETLYDSWLWNIKQVTNDYRSYHINKGSHNTKVGVIDSGI
                     DFNHPDLKNNIVDTGESFVPVEDNTQDFYGHGTSVAGIIAANGGVKGVGPNLGLVPYKV
                     FDKNGKSKTSWVISAIVKATEDDMDVINLSLSTFLSKKDKEDRETIKLFEKAFKFARKH
                     NTLIVAAAGNHGYDISNSKKLAQQLGKPKDNILHLPGGDNDVITVSATTAQNTKASYSN
                     YGKNISIAAPGGDLDPSFLDTNKIDLYSLVWTTSPVNIPQTPLSKSLGFQEGYEPTLGT
                     SVAAPIVTATAALLKTEYYEKYGEEMPIRKVEENLYQNTDHVENLDKNEVGSGIVNAYE
                     SLLNIER"
     misc_feature    complement(7342..7356)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.9"
                     /tool="antismash"
     gene            7350..9119
                     /locus_tag="KXD37_RS21895"
                     /old_locus_tag="KXD37_21655"
     CDS             7350..9119
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469908.1"
                     /locus_tag="KXD37_RS21895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21655"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_223255281.1"
                     /transl_table=11
                     /translation="MTNPNFNSKEFFFLLRKTRPNIRLFILAIFLSGLSAIASTLVPHY
                     LKSLIDYYNILEKINLWDLLGLLAIFLISGVIGAVGSYMLSVVGYNVVANLRNLLWEKI
                     VILPIEFYDKNRSADIASRFVNDTTVIYNLVSNSFSQFINAILIVLFCGFWLFYYDWQL
                     TLVIIVAIPVYLLIFIPLGRILSKLSKMTQSLTGELNVRAVETISSIRLIKSSTAEKLQ
                     VERGKEDIEALRNIGLKQTKWMVILNPIINLMMMLIIISIIGFGGVKLANGSLSPGTFI
                     AFLTLMFYIIGPLNNFGLFFTQIQKTIGATERISQLIYEQGEDQHKGKELAETYKDLVI
                     ENLSFCYGKEDKAFSLNNINLIIKGGSVNALVGPSGSGKTTIISILERYYNPNSGNIYF
                     GEENIELFSLKSWRSQIGYVAQNHDLISGTIRDNLIFGLENPPDEKKIVEACKKAYAWQ
                     FISELPNELETNIGEKGLNLSGGQRQRIAIARMFLKDPNIIFLDEATASLDSHSEQIVN
                     EAMKKLMKDRTAIIIAHRLSTIINADNIIFMENGEVTGQGNHWELKRSHKLYRQFCEQQ
                     FKEDSTDPLVLTN"
     gene            9149..11746
                     /gene="lanKC"
                     /locus_tag="KXD37_RS21900"
                     /old_locus_tag="KXD37_21660"
     CDS             9149..11746
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013351405.1"
                     /locus_tag="KXD37_RS21900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21660"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_106022407.1"
                     /sec_met_domain="micKC (E-value: 1.4e-140, bitscore: 462.3,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 5.1e-18, bitscore: 57.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.3e-18, bitscore:
                     59.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLVYFQHMSENSKYYIEKSPNAETDPYEVHNMPNYYTVSTEY
                     KSPWKFYNNPNHTLKEQGWKIHISATMNNAQDILKVVSQIIFKHQIPFKHIKDKQSLFN
                     MNSKHGNRTSSGKFIAIYPSSDNMFFGLLNELYEELKHYENGPYILNDKSWKGSNIYYR
                     YGAFKNIYNERGELCIKDENGNLIPDNRQPYYKIPEFVSDFDQYLDTKNNLLDTQDVSN
                     FNDYEFQGVLRFNNGGGIYTGIRKSDGKKVVIKEGRPKVGLDGQLNDAIDRLNIEYEAL
                     NTLTEVEGVVNVLDYFKAWKHVFLVEEFVEGVTLQSWCAINYPFNIENDKNEYISKVKK
                     IINSLIETIKLVHSKDVGMGDLQPQNIMITPESNVKIIDFEAASALSEENGALQTIGYT
                     NKKNKNHKERDWYALKKVLRFCILPIGPVIDIEESIKKKHDMWIENEFGKDVYQYVVNT
                     ENLCDRYLSDTKEKIFKNNYDSEIKKEMDMSKVINGLRNSIESNMLPNSSLIHGDVRQF
                     VMPSGKLNVLTGGTGAALALYRSGNVNKQVRDWIENVLLKKLHVLNDDIGLFTGRAGIA
                     ATLYELGYIEEAMNLFNNLSYEDMKDISLRSGLSGIGLSLISLYLEEDNDDFLVTSEKI
                     ADQIENRIIEDDKLSATDFAAVPIGLIDGWSGISLFYAALYSVTKKEKYYVKSKEYIEW
                     DLKHCKVDEETNTLQTYDDQNPRLLPYLSGGSIGIGVAIWYLNYVGNNNLFREELEQII
                     NLNKVRIAYSGGLFDGVGSFLLIPSMTKENNEISQQIELALKKLELFLIRKDDQVLFPG
                     NFSFRLADDYYSGSAGIILGINSIQFSNPLYWLPIIKIDSFLNKTKKELLLNN"
     gene            11836..11955
                     /locus_tag="KXD37_RS21905"
                     /old_locus_tag="KXD37_21665"
     CDS             11836..11955
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="KXD37_RS21905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21665"
                     /product="class III lanthipeptide"
                     /protein_id="WP_188323619.1"
                     /transl_table=11
                     /translation="MKEVLELQQFNEKSEVEPAAWTVTLTTISVTLSTISNHC"
     misc_feature    complement(11861..11875)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.39"
                     /tool="antismash"
     gene            12002..12130
                     /locus_tag="KXD37_RS21910"
                     /old_locus_tag="KXD37_21670"
     CDS             12002..12130
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469909.1"
                     /locus_tag="KXD37_RS21910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21670"
                     /product="class III lanthipeptide"
                     /protein_id="WP_188323620.1"
                     /transl_table=11
                     /translation="MKDVLELQQLSEGSDVEASKGKGGLLTLITTIVGTSTISNNC"
     CDS_motif       12002..12073
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKDVLELQQLSEGSDVEASKGKGG"
                     /locus_tag="KXD37_RS21910_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12074..12130
                     /prepeptide="core"
                     /locus_tag="KXD37_RS21910_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.50"
                     /molecular_weight="1738.0"
                     /monoisotopic_mass="1737.0"
                     /core_sequence="LLTLITTIVGTSTISNNC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLSEGSDVEASKGKGG"
                     /leader_location="[12001:12073](+)"
                     /alternative_weights="1756.0"
                     /alternative_weights="1774.1"
                     /alternative_weights="1792.1"
                     /alternative_weights="1810.1"
                     /alternative_weights="1828.1"
                     /alternative_weights="1846.1"
     gene            12158..12277
                     /locus_tag="KXD37_RS21915"
                     /old_locus_tag="KXD37_21675"
     CDS             12158..12277
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="KXD37_RS21915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21675"
                     /product="class III lanthipeptide"
                     /protein_id="WP_187265387.1"
                     /transl_table=11
                     /translation="MNEVLELQQLSKGSEVETAGWTLLTTLIGTSTISNSCNK"
     CDS_motif       12158..12208
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNEVLELQQLSKGSEVE"
                     /locus_tag="KXD37_RS21915_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12209..12277
                     /prepeptide="core"
                     /locus_tag="KXD37_RS21915_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-1.30"
                     /molecular_weight="2120.4"
                     /monoisotopic_mass="2119.2"
                     /core_sequence="TAGWTLLTTLIGTSTISNSCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEVLELQQLSKGSEVE"
                     /leader_location="[12157:12208](+)"
                     /alternative_weights="2138.4"
                     /alternative_weights="2156.4"
                     /alternative_weights="2174.4"
                     /alternative_weights="2192.5"
                     /alternative_weights="2210.5"
                     /alternative_weights="2228.5"
                     /alternative_weights="2246.5"
                     /alternative_weights="2264.5"
     gene            12298..12429
                     /locus_tag="KXD37_RS21920"
                     /old_locus_tag="KXD37_21680"
     CDS             12298..12429
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469912.1"
                     /locus_tag="KXD37_RS21920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21680"
                     /product="class III lanthipeptide"
                     /protein_id="WP_188323623.1"
                     /transl_table=11
                     /translation="MKDVLELQQLNEGSDVEASKGKGGLLTLITTIVGTSTISNNCG"
     CDS_motif       12298..12369
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKDVLELQQLNEGSDVEASKGKGG"
                     /locus_tag="KXD37_RS21920_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12370..12429
                     /prepeptide="core"
                     /locus_tag="KXD37_RS21920_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.70"
                     /molecular_weight="1795.1"
                     /monoisotopic_mass="1794.0"
                     /core_sequence="LLTLITTIVGTSTISNNCG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLNEGSDVEASKGKGG"
                     /leader_location="[12297:12369](+)"
                     /alternative_weights="1813.1"
                     /alternative_weights="1831.1"
                     /alternative_weights="1849.1"
                     /alternative_weights="1867.2"
                     /alternative_weights="1885.2"
                     /alternative_weights="1903.2"
     gene            12569..12700
                     /locus_tag="KXD37_RS21925"
                     /old_locus_tag="KXD37_21685"
     CDS             12569..12700
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469912.1"
                     /locus_tag="KXD37_RS21925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21685"
                     /product="class III lanthipeptide"
                     /protein_id="WP_188323623.1"
                     /transl_table=11
                     /translation="MKDVLELQQLNEGSDVEASKGKGGLLTLITTIVGTSTISNNCG"
     CDS_motif       12569..12640
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKDVLELQQLNEGSDVEASKGKGG"
                     /locus_tag="KXD37_RS21925_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12641..12700
                     /prepeptide="core"
                     /locus_tag="KXD37_RS21925_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.70"
                     /molecular_weight="1795.1"
                     /monoisotopic_mass="1794.0"
                     /core_sequence="LLTLITTIVGTSTISNNCG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLNEGSDVEASKGKGG"
                     /leader_location="[12568:12640](+)"
                     /alternative_weights="1813.1"
                     /alternative_weights="1831.1"
                     /alternative_weights="1849.1"
                     /alternative_weights="1867.2"
                     /alternative_weights="1885.2"
                     /alternative_weights="1903.2"
     gene            12840..12971
                     /locus_tag="KXD37_RS21930"
                     /old_locus_tag="KXD37_21690"
     CDS             12840..12971
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469912.1"
                     /locus_tag="KXD37_RS21930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21690"
                     /product="class III lanthipeptide"
                     /protein_id="WP_188323623.1"
                     /transl_table=11
                     /translation="MKDVLELQQLNEGSDVEASKGKGGLLTLITTIVGTSTISNNCG"
     CDS_motif       12840..12911
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKDVLELQQLNEGSDVEASKGKGG"
                     /locus_tag="KXD37_RS21930_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12912..12971
                     /prepeptide="core"
                     /locus_tag="KXD37_RS21930_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.70"
                     /molecular_weight="1795.1"
                     /monoisotopic_mass="1794.0"
                     /core_sequence="LLTLITTIVGTSTISNNCG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLNEGSDVEASKGKGG"
                     /leader_location="[12839:12911](+)"
                     /alternative_weights="1813.1"
                     /alternative_weights="1831.1"
                     /alternative_weights="1849.1"
                     /alternative_weights="1867.2"
                     /alternative_weights="1885.2"
                     /alternative_weights="1903.2"
     gene            13431..13715
                     /locus_tag="KXD37_RS21935"
                     /old_locus_tag="KXD37_21700"
     CDS             13431..13715
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097694.1"
                     /locus_tag="KXD37_RS21935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21700"
                     /product="YfzA family protein"
                     /protein_id="WP_021481197.1"
                     /transl_table=11
                     /translation="MDKVYKKRPLYKRSWFQTFLAFLVSQLYFNFVELTGWGPKYREMN
                     GFPANIVELDFFQTYLSFYDNPWFNIITVFLGVFTIIQIITGITKDIRN"
     misc_feature    complement(14327..14343)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 20.73"
                     /tool="antismash"
     gene            14468..15451
                     /locus_tag="KXD37_RS21940"
                     /old_locus_tag="KXD37_21705"
     CDS             14468..15451
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004430511.1"
                     /locus_tag="KXD37_RS21940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21705"
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="WP_263463735.1"
                     /transl_table=11
                     /translation="MTDNFWRELPRPFFVLAPMEDVTDVVFRHVVSEAGRPDVFFTEFT
                     NSESYCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPENFRQMSIGMAELGFKGLDINMG
                     CPVPNVAGNGKGSGLICRPEVAAELIQAAKAGGLPVSVKTRLGYTDIDEWRDWLTHVLK
                     QDIANLSIHLRTRAEMSKVDAHWELIPEIKKLRDEVAPDTLLTINGDIPDRQTGLKLAE
                     QYGVDGIMIGRGIFTNPFAFEKEPKEHSSKELLDLLRLHLDLHDKYSALEARPYKPLPR
                     FFKIYLRGFRGASELRNQCMNTKSTDEVRALLDDFESKYLDGVEQQ"
     gene            15690..16874
                     /locus_tag="KXD37_RS21945"
                     /old_locus_tag="KXD37_21710"
     CDS             15690..16874
                     /GO_function="GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010333408.1"
                     /locus_tag="KXD37_RS21945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21710"
                     /product="amidohydrolase"
                     /protein_id="WP_101860289.1"
                     /transl_table=11
                     /translation="MMDEYASIYKNVIEWRRHLHQYPELSFQEEKTAQFVYDTLSSFEN
                     LEISRPTRTSVVARLSGARPGKRIGLRADMDALPIQEEHDSHFRSRHPGVMHACGHDGH
                     TAMLLGAAEILSQKKDELSGEVYFIFQHAEEVHPGGAQEMVKAGVADHLDLCIAIHLFS
                     AMPLGKIGLASGPVTANSDRFDITIKGKGGHASQPEQCIDPLVIASQVITHLQSIASRH
                     TDPAERLVLSVTMCHAGSAYNVIPDTVTLGGTVRTFRKEVRANTEALMETIIKGVTEAH
                     GASYDFDYRHGYKSVVNDPNVTELVRQAAENLWGKDQVFPLAPMMGGEDFSAFSERVPS
                     CYIALGAGTGEMIYPHHHPKFTFDEKALSAGVKLFVNSVYFILHSRESISMKIN"
     gene            16896..18431
                     /locus_tag="KXD37_RS21950"
                     /old_locus_tag="KXD37_21715"
     CDS             16896..18431
                     /GO_function="GO:0015558 - secondary active
                     p-aminobenzoyl-glutamate transmembrane transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:1902604 - p-aminobenzoyl-glutamate
                     transmembrane transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010333409.1"
                     /locus_tag="KXD37_RS21950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21715"
                     /product="AbgT family transporter"
                     /protein_id="WP_174754409.1"
                     /transl_table=11
                     /translation="MAKHLPEVMTADSLQKIEHKGILKWIEKAGNKLPDPFMLFIYLSM
                     IIIAMSVLLAGNAVTHPGDGKEVAVKSLLSTEGIHWMLTEAVNNFVQFPPLGLVLTMVL
                     GIGLAERVGLIEAVLQKMMAHVPKAIISYSVVFVGILGNLASDAAWVIIPPVGALIFMA
                     AGRHPLAGFAAAAAGVGSGFTANLMIAGTDALLSGITTQVAQTVDKNAQVSAVDNWFFM
                     AASVFVLAFIGAWVTDKIVEPRLGSYRGEYKPEMAALTGKEIKALKAAGAAALLYAGVI
                     ALLVVPEGALLRDPENGSILSSPFLKGIIPIILLFFITVSVVYGIVAGRIKNQTDVPRL
                     MGDSIKGMSGFIVLVFVISQFIAFFTWSNMGIFMAVKGADFLESIHLTGFPVLIGFSLL
                     TCVVSLFITSGSALWALLAPVFIPMLMLLDFHPAFIQIAYRIADSATNTITPMNPYLPM
                     LMAYYKRYKSDAGFGTVISTMIPYTVLFFLAWLLMMFIWYAFGWPIGPGVYAK"
     gene            18455..19711
                     /locus_tag="KXD37_RS21955"
                     /old_locus_tag="KXD37_21720"
     CDS             18455..19711
                     /GO_function="GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003239809.1"
                     /locus_tag="KXD37_RS21955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21720"
                     /product="amidohydrolase"
                     /protein_id="WP_263463736.1"
                     /transl_table=11
                     /translation="MDMIQIRRDFHRHPELGFTEFRTAGKVVETLQALGYHVTYGKDAM
                     DGEARRGVPSEKELKRAFDRAIENGADPDIIAPMKGGYTAVIGRLEGNTPGPVVALRFD
                     MDALPITESADADHGPHAKGFRSAFEGNMHACAHDGHTAIGLGVAEALAHRNFAGTLKL
                     IFQPAEEGVRGAYAVTEKGMLDDVDYLLCHHLGTNVPLGEVYGGAEGFLATTKMAAHFR
                     GVSSHAGAAPEHGRNALLGAATALLNIHAIPRFSSGDTRINVGVLEGGTAANIIPQHAK
                     MIIETRSDSEEVNRDLEERVRKINAHSAAMHELEHEVEIIGGAIPIKCDEEMVSTVLEA
                     AGEVGGFSSLQGIQTGSRGSEDASYMIKRVQERGGKGTYMIIGTDIAAPHHHEKFDIQE
                     DILPRSVQLLKQAALKLLK"
     gene            19820..20575
                     /locus_tag="KXD37_RS21960"
                     /old_locus_tag="KXD37_21725"
     CDS             19820..20575
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KXD37_RS21960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KXD37_21725"
                     /product="hypothetical protein"
                     /protein_id="WP_127695668.1"
                     /transl_table=11
                     /translation="MKRMHFCTGIGLLLIVISAYPIFVLLRENIIDHNVTNRYDIHYAY
                     QDKQGYEPAIDTQNINIFNHHIRIIETKTGKHAPLTSWDKDENVPAGEIVNIQYQLDGR
                     DLSSPSEVWLSNRERGGRYFSWLEILTVKDRKTDQNLVYIVQRITDDQISLEKSKWKII
                     RIHQDGTVKEKLLSYSDRSKDPLSVKLLNFSYVGGNSMGYHSDMYEVIPNVIFPLLYPL
                     ITVAVGCAIMIGILIIVIVQKIKGVRKSI"
     misc_feature    complement(19868..19888)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 24.85"
                     /tool="antismash"
     gene            20572..21024
                     /locus_tag="KXD37_RS21965"
                     /old_locus_tag="KXD37_21730"
     CDS             20572..21024
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388685.1"
                     /locus_tag="KXD37_RS21965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21730"
                     /product="hypothetical protein"
                     /protein_id="WP_106021618.1"
                     /transl_table=11
                     /translation="MKRLCIIPCGAKKIWDVQPDAGPTRAEDAYLSPFHQACERYAKAF
                     FDEWVILSAKHGFLRPDDIVPENYDVAFGSGHPEIMTEEKLSRQYREKGFLEKEELVML
                     GGKKYRKVLSTVVGDHQHISWPLAPYKGIGYMLQALNRAVEEKQEL"
     gene            21054..21743
                     /locus_tag="KXD37_RS21970"
                     /old_locus_tag="KXD37_21735"
                     /pseudo=""
     CDS             21054..21743
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388686.1"
                     /locus_tag="KXD37_RS21970"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_21735"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKRMVFGFLAIAVCGSGFYIYHILFGDPFSKNAAEQKLTSYVKQT
                     YPQKEIKITNGVYNAKTSEYVFQANTQSQSY"
ORIGIN
        1 cttaacagca ttaatcgaac cacgaccgcc atcgtagaac gcactgtcaa agaatacatt
       61 tattattata acaacattcg tattcaaacg aaactaaaca gccaatcacc gataagctat
      121 cggcaatcgg ctgtataaaa ggtgttttga tccctgtctc aaaaacaggg gtcagtcccg
      181 caatggagag gctttttcta tttttctatg cattttatta aagcggccca atctaggttt
      241 ccaagccctt tttcaatacc gctttcaaaa tggcctttcg ccagctcggc aagagggagg
      301 tttgcagaaa cctgccccgc ggcggcgagc gccagattgg tgtccttcaa ccctaatgac
      361 attttaaagc ccgccggctc aaatgtttgc tcggccatga tcgttccgta attttgatat
      421 acaggggagc cgaaaagcgc gttggcgatc tctaaaaatt gtttttgctc taatccgtat
      481 ttctccatca tcaggaatga ttcagataac gcctccagca tagatacgag caggaaattg
      541 atgctgattt tcgctgcgtt tgctgttttg ctttcttcgc cgacgtcaaa cacttgctga
      601 ctcaagcttt cgagcagagg ttttgctgtt ttttttgctt ccgcgggtcc tgccgctata
      661 atgcgaagcg cggcttttgc ggcggcatcc ggtcttccca gcacaggagc cgcaaggaag
      721 gattgtcctt tttctgcatg ggcggccgca agtttttctg agaactccac actgatcgtg
      781 ctcatcgaaa tgtgaatgcc attctctgat aacccttcaa tcaatccgtc tttgccgaac
      841 gtcacgttgc tgacagaatt gtcatcggaa agcattgtca cgacaatatc agcggtctcg
      901 gccgcctggc gcggcgtttc tgccacttgg gcgccctggg atgcgaattc ttccgtcttt
      961 tctttcgtcc gattgtatac tgtcaaacga tgacctgctt gtagcacgtt tcgggcaatg
     1021 ggctgtccca tattgccgag tccgatcaca gcgattttca atctgatcac tccctgaaca
     1081 tttttttcat tatatacaaa atgaacagga tatgctggaa atcggcttac caaaataaaa
     1141 agaacagctt cacgctgtcc tcatttaaag atgttgaacc atcctttatg tacaaaccat
     1201 atcagcatgc cggccacaag agcggccatc aggccaagca cggcaaaata tccgtatttc
     1261 cagtgaagct ccggcatgtt gtcgaagttc atgccgtaaa cgccggcgat aaacgtgagc
     1321 gggataaaaa tcgtagacac gatggtcaat gtcatcataa tcgcattcat ccggttcgaa
     1381 ttcagtgtca cgtagctgtc acgcaaatcg gacgtcatgt cgcggttaga ttccacaatt
     1441 tctgaaagct ttaataaatg atcataaata tcgctgaagt atgcctttgt ttcccgctgc
     1501 tccttcacat ggtcaagact taaaatccga tacagcaaat cacgcatcgg aataatggtc
     1561 cgcctgagat gcaataggtc agttctgagc tcaaacacct cgctcatcag cgtcccgtac
     1621 gttttgtggc tgcggctgtc ttcaatctca ttcagccggt cttctatttt gtacaccaga
     1681 ggaaaatatt catcaacaag ctgatccatg atcatgtaag aaatatgccc cggccctttt
     1741 ttaaacatgt ccggtgaagc atataatcgc tcccggactt tggcgatacc gggcgtttcg
     1801 tgtaaatgaa aggtgacgac aaatgtttcg ccttgaaaga tatcgacttc ctcggtctca
     1861 agtgtttcct gattcagcgc atgaagcacg taaaagcgat agccatcgta atggtcaagc
     1921 ttcgggcgct gcatatgctg aaagcaatct tcaatcgcaa gcggatgaaa atgaaaaaaa
     1981 tctctcaata acgcggtttc cgtttcctcc gggccgtaaa aatcaaccca gtaccacgca
     2041 atatccggct gttcaacccg ttcgatcggt atatttttca aaagctgatg ctgtgttgtg
     2101 atagcggtaa tgttgatcat aaacaaccct ccacgtgcca ttatatcatg cggccttttt
     2161 cagaaaagta tacagtgttt tctacaggtt tccagccgcg tggtatactg aacaaaaaac
     2221 ggaaaaaggg ctgatcatat gtggaaagaa aaagtatcgg tcacaccgcc gtaccatttt
     2281 gaccgtgtgc tcgacaggct ggcgttagac cctctgaatg cagttgattt gaaagcgcgg
     2341 gacataagag tgccgatcag aaataaggcc ggtgacgtat gtattgtgaa ggtgcaggct
     2401 ttaggccatg cggacgagcc cgagtttctc gtcagcgggg aaacagagca ggaagacatg
     2461 atgaaggaaa tcaaacggat ttttcaatgg gaacatgatt tgcagcatgt ccttgatcat
     2521 ttctcaaaaa cgaatctttc cgcgattttt gaagagcatg caggcacgcc gctggtatta
     2581 gactacagcg tgtacaactg tatcatgaaa tgcattgtgc atcagcagct gaatttatct
     2641 tttgcgtaca ccttgacaga acggtttgtc caaaccttcg gcgagcagaa ggacggcgtg
     2701 tggtgctatc cgaagccgga aacgattgcg gcgctggatt atcaagatct ccgcgagctc
     2761 cagttcagca tgagaaaagc ggaatacgcc attgatacgt caaggatgat tgcagaaggc
     2821 acactcgatt tgtcagagct gccccaactg acagatgaag acatcatgaa gaaactgatc
     2881 aaaatcagag gcatcggccc atggacagta caaaacgtgc tgatgtttgg gctcggacgg
     2941 cccaatttat tcccgctggc cgatatcgga ctgcaaaacg cgatcaaacg ccatttcaat
     3001 ttggacgaca aaccggcaaa ggatgttatg ctcgcgatga gcaaggagtg ggagccttat
     3061 ttgagctatg cgtcgttgta tttgtggagg agtatagaat aattcgtctg acaatgaagg
     3121 aaatcgtgca aacgtgttat actagaaaga tgtgaaaaaa acatttcact ttctgccatc
     3181 tgcagaaagc ttcatataga aacggagaga acaacgtgaa ccaacaaaac aaaaaggcgc
     3241 tcgtcgaact gaaagtcgga cagacctttc cgctgacgat taaacgtctc ggaattaacg
     3301 gggaaggcgt cggctatttc aagaaaaaag tcgtgttcgt gcccggcgcg cttcctggtg
     3361 aagaggttgt cgtccaagcg acgaaagtgc agccgaagtt ttcggaggga cggatcaaga
     3421 agattcgcaa ggcttcggag catcgggtgg caccgccttg ccctgtctac gagcagtgcg
     3481 gcggctgtca gcttcagcat cttgcataca gccagcagct tcgggaaaag cgcgacatcg
     3541 tcatccagtc tctggagcgc catacgaagt ttaaagtcga aaacatggat atcagagaaa
     3601 cggtcggcat ggacaatcca tggaattacc gcaacaaaag ccaattccag atcggacgct
     3661 cacaaagcgg cagcatcatc gccggcttat acggccttga ttctcatgat atcgtgccga
     3721 tcaaagactg tgtcgtccag catccggcaa caaataaaac aacaggcatc gtccgccgca
     3781 ttttagagga tttcaatgtg tctgtttata atgaacggaa aagaaaaggc gacgttcgca
     3841 cgatagtgac gagagtcggc tttgaaacag gcgaagtgca ggtcgtgctt gtgacagcaa
     3901 aagaaacgct tccgcataag gaagaaatcg tcaaagcgat ccaaaagcgg ctgcctgagg
     3961 tgaaatccat tattcaaaat gtaaacggag cgaaaacctc tgttattttc ggtgagaaat
     4021 caaaacccct cgccggacat accgtgattc aagaagtgct cggcgacgta tcttttgaat
     4081 tgagcgcccg cgccttcttc cagctcaatc cggagcaaac cgtcaagctg tatgacgaag
     4141 tgaagaaagc ggcgcagttg accgggaaag aaaaagtcgt tgacgcgtat tgcggcgtcg
     4201 gcaccatcgg catgtgggtg gcggacggag cgaaggaagt ccgcggcatg gatgtcatca
     4261 aggaatctat tgatgatgcc aagaaaaacg ccaaaaaaca cggcatgaca aatgccacgt
     4321 acgtaacagg aacagccgag cactggctcc cgaaatggac gaaagaaggt ttccgcccgg
     4381 acgtcgtcat cgtagatccg ccaagaaccg gctgcgacgg aacattctta gacacgatca
     4441 aaaaagtaaa accgaaacgc tttgtatacg tatcctgcaa tccatccacg cttgcgaaag
     4501 acttgcaggc gctgtcgaag gactatcgcg tggaatatat tcagcctgtc gatatgtttc
     4561 cgcagacggc tcacgttgaa gcggtggcga agcttgtatt gaaatcgtct cattaagtcc
     4621 taatcagatc tggatttcgg tagaatgaac attgccgatt tccgggtctt tttcatgcgc
     4681 aaaccttgac ctgactgtct tttctgaatt ttatcttcct tcatttcttg gagatcttta
     4741 ttttaactga cgaaaagagt tgaaaaagcg tgttgaaaag cgggtgaaaa acagccaatt
     4801 ttgaacagaa aaagtatgaa aatgggggtt cggtaggaaa agtctatttt aactcgaacg
     4861 gtggaatgcg ggttggaagg gtctgattta gaaatgtata ttatttttgt acatagtaag
     4921 agggaagaga tttgtttcgt ctgtaatatt taaaacataa atttacaatt ggagatataa
     4981 gagaagggag ttcatgtctg tccttttgag tggaattgat gaaagcagca ttacttaacg
     5041 tatttttaaa aaataataaa gaagctagaa cacaactaaa agagtatatt ctttggtcaa
     5101 ataacagcta tttcttagta aattctagct ttctacagtc tttaattcga atgttataga
     5161 aaaaatgaac tgcctaaacg ttaaccaagg tatacaaaga cgacttactt tctaatgata
     5221 ggttctaaag gagagtggat taatttccta tttttattat ttggttggct aatctttgaa
     5281 taccggctta ggtgctgtta catgctgggt ttagtgcgga taaagaaatc aacaagcttg
     5341 tagctaaaga attgaatact caggctgtaa taaaatatga cacaagcaac ttagtaatag
     5401 taagttgctt gtgaaatatc tcataaatac ggtttatttc atctctagct tcatcatcat
     5461 tatcgtctag taatcttttt ttatttatca aagtattttt agtgaaagtt cgataactgc
     5521 ttaatatctt ctatctctca atattaagca atgattcgta agcatttacg ataccgctac
     5581 caacttcatt cttatctaag ttttcaacgt ggtctgtgtt ctgatataag ttttcttcaa
     5641 ccttacgaat tggcatctcc tctccgtatt tttcgtagta ttctgtcttt aatagggctg
     5701 ctgtagcagt tactattgga gctgctacac ttgtccctaa agtaggttca tatccctctt
     5761 gaaagcctag tgacttactt agcggagttt gcgggatatt tacaggggaa gtagtccata
     5821 ccaagctata tagatcaatc ttatttgtat ccagaaaact tgggtcaaga tcaccacctg
     5881 gagctgcaat tgagatgttt tttccataat ttgagtaaga agcttttgta ttttgcgctg
     5941 tggtggcaga tacagtaatt acatcgttat caccaccagg aagatgtagg atattgtcct
     6001 ttggtttacc taattgttgt gcaagttttt ttgaatttga gatatcatat ccatggtttc
     6061 cagctgctgc aacaattaaa gtattgtgtt ttctagcgaa tttaaaagct ttttcaaaaa
     6121 gttttatagt ctctctatct tctttatctt tttttgataa gaaagtagat aaacttaaat
     6181 taattacgtc catatcatct tccgtagctt taacaattgc gcttataacc caacttgttt
     6241 tagatttacc gtttttatca aatactttat acggcactaa accaagattt ggtccaactc
     6301 cttttacacc cccattagca gcaattatcc cagccacaga agttccatgc ccataaaagt
     6361 cttgtgtatt atcttcaact ggaacaaaag actctccagt atctacaata ttatttttga
     6421 ggtctggatg attgaaatct atgcctgaat cgattactcc tacttttgta ttatgagatc
     6481 ctttatttat atgataactt cgataatcat ttgtaacttg cttaatattc cataaccaac
     6541 tgtcataaag agtttcatta tcttccgtga attgtgatga aaatgccact ttatcaggaa
     6601 tctgtttact tttatcagga agagaaatat ctttatcctc aataatttct tttgcgtcta
     6661 atttttcttt agcaatatct ttgattgctg aaaattggct tggttttata ttatctatta
     6721 ccaataaatc tagttcttta atataatttg tttctatatt tgaatacttt tcctgaacct
     6781 tgtttattgt cgattcactt acttttgagt cgaggttaat tatgatagat tcatcataat
     6841 ttgattcttc agcatgagag cttataggct gtaaactgga tacaattaca aatatgaaaa
     6901 ccatcgaaat tcttcttaaa ttcttcattt tttatactcc ttttccttaa tacagttcat
     6961 taaataataa gattgtatat aatttacccc ctttccaaaa ataagtatat taaattcaag
     7021 tttataaaat ataagtaaat cagtcaatac atatttttct aattatcagt aattatcccg
     7081 agaaattcac ctttagtatg attaaattaa acttcttttt attcttttat actacacctg
     7141 tggttttgcg ggtcaaaatt actatgggta aatatacatg agtagaataa tgcaaaacca
     7201 aagacctgtt ttttcataat ttgtaaaatt atatattgac ttgcagttat tatgtgtgaa
     7261 atattgttta taggaatatt aggaaaggta tcatgagtca ttcgatttaa aaagtcgaaa
     7321 cattggaata aatggaagag gtgaaaatga tgaccaaccc caattttaac tcgaaagagt
     7381 ttttcttctt actgagaaaa accagaccga atataagatt atttatattg gcaatatttt
     7441 taagtggatt aagcgcaata gcttctactt tagtgcctca ttatttaaaa agtctaatag
     7501 actattataa tattcttgaa aagatcaatt tgtgggatct tttaggtctt ctggcaatat
     7561 ttttaatcag cggagtaatc ggggcagttg gtagttatat gttaagtgta gtaggatata
     7621 acgttgttgc aaatctcaga aatttattat gggaaaagat agtaatacta cctatagaat
     7681 tttacgataa gaatcgttct gcagatatag caagtagatt tgttaatgat actacggtga
     7741 tttacaactt agtaagtaac tctttttcgc aatttattaa tgctatatta atagtgcttt
     7801 tttgtggatt ttggttgttt tactatgatt ggcaattgac attggtgatt atcgtagcaa
     7861 ttccagttta tttgttgatt tttatacctt taggaagaat tttatcaaaa ttatctaaaa
     7921 tgacacaaag cttaacagga gaattaaatg taagagctgt tgaaacaata tcctcaataa
     7981 gactgattaa atcttcaact gcagaaaaat tacaagtaga aagaggaaaa gaagatattg
     8041 aagctttaag aaatataggc ctaaagcaaa caaaatggat ggttatttta aaccctatca
     8101 ttaatttaat gatgatgctt atcattatta gcataattgg attcggaggg gttaaattag
     8161 ccaatggaag tttatcgcca ggaaccttta ttgcatttct gacacttatg ttctatatca
     8221 taggtccact taataacttt gggttattct ttactcaaat acaaaagacg ataggtgcaa
     8281 cagaaagaat ttctcaattg atatatgagc aaggagaaga tcagcataaa gggaaagaat
     8341 tagcggaaac ctataaagat ttagtgattg aaaatttatc attttgctat ggtaaagagg
     8401 ataaggcatt ttccttgaat aatattaatt taataataaa agggggaagt gtaaatgcct
     8461 tagtaggtcc tagtggtagt ggtaaaacca caatcatctc tattctggaa agatattata
     8521 atcctaatag cggaaatatt tattttggtg aagagaatat tgagttattt tcattaaaat
     8581 catggcgtag ccaaatagga tatgtagcac agaatcacga tttaataagc ggtactatta
     8641 gagacaatct catctttggt ttagaaaatc ccccagatga aaaaaaaata gtagaagcat
     8701 gtaagaaggc atatgcatgg caatttataa gtgaattgcc taacgagtta gaaactaata
     8761 ttggagaaaa aggtctaaac ttatcaggag gacaacgaca aagaattgct attgcgagaa
     8821 tgtttctgaa ggatccaaat ataatctttt tggatgaagc aactgcaagt cttgacagtc
     8881 attctgaaca aattgtgaac gaagcaatga agaagctcat gaaggataga accgctatta
     8941 taatagcaca taggttatcc accattataa acgctgacaa tatcattttt atggaaaatg
     9001 gtgaggtgac aggtcaaggg aatcattggg agttaaagcg tagtcataaa ttgtatcgtc
     9061 aattctgtga gcagcagttt aaagaagata gtaccgatcc attagtatta accaattaaa
     9121 aagagcgctt aagagaggcg agaacaaaat ggacaaaaaa ttagtttatt tccaacacat
     9181 gagtgaaaat tcaaagtact atatagagaa aagcccaaat gcagagactg atccatacga
     9241 agtacataat atgccaaatt actatactgt tagtacagaa tataaatcac cgtggaagtt
     9301 ttataataat cccaatcata ccctcaaaga acaaggctgg aaaatacaca taagtgcgac
     9361 aatgaataat gctcaggata tattaaaagt tgtgagtcaa attatattta aacatcagat
     9421 accatttaag catattaaag ataaacaatc tctttttaat atgaattcaa agcatggtaa
     9481 tcgaacttca tctggaaaat ttatcgctat ctatccttct tctgataaca tgttcttcgg
     9541 gttattaaat gaactttatg aagaattaaa acactacgag aatggcccat acatactaaa
     9601 tgacaaatca tggaagggca gcaatatata ttaccgatac ggtgcattta agaatattta
     9661 caatgaaaga ggagaactgt gcattaaaga tgaaaatgga aatttaatcc cagacaatag
     9721 gcagccatat tataaaatac ctgaattcgt aagtgatttt gatcaatatt tagataccaa
     9781 gaataactta ttagatactc aagatgtaag taattttaat gattatgagt tccaaggagt
     9841 ccttaggttt aacaatggtg gcggtatata tacaggaata agaaaatcag atggaaagaa
     9901 agtggtgatc aaagaaggga gacctaaagt aggattagat ggtcaattaa atgatgcgat
     9961 tgatagattg aatatagaat acgaagcatt aaatacactt acagaagttg aaggtgttgt
    10021 taatgtgctc gattacttta aagcatggaa acatgtattt ttagttgaag aatttgtaga
    10081 aggtgtaacc cttcaatcat ggtgtgcaat caattatcct ttcaacattg agaatgataa
    10141 aaatgaatac attagtaagg tgaaaaaaat aattaatagc ttgatagaaa caattaaact
    10201 agtacatagt aaagatgttg gtatgggaga tttgcaaccc caaaatataa tgattacccc
    10261 cgaatcaaat gttaagatta ttgattttga ggctgctagc gctctctctg aagaaaatgg
    10321 agcgttgcaa acaattggat atacaaataa gaaaaataag aatcataagg agcgagattg
    10381 gtatgcacta aagaaagttt taagattttg tattctgcca ataggtccag ttattgatat
    10441 agaagaaagc attaaaaaga aacatgatat gtggatagag aatgaatttg gtaaagatgt
    10501 ttatcaatat gttgtaaata cagaaaatct atgtgacaga tacttatctg acaccaaaga
    10561 aaagatattc aagaataatt atgacagtga aatcaaaaaa gaaatggaca tgtcaaaagt
    10621 tataaatgga ttgagaaaca gcatagagag taatatgttg cccaacagct cgctaattca
    10681 tggcgatgtg cggcaatttg taatgccatc tggaaagtta aatgtactaa ctggaggaac
    10741 tggagctgca ttggcattgt acagatctgg aaacgtcaac aagcaagttc gggattggat
    10801 tgaaaatgtt ttactgaaaa aattgcatgt acttaatgat gatattgggt tatttacagg
    10861 acgagctggt atcgcagcaa cattgtatga attggggtac atagaggaag ctatgaactt
    10921 attcaataat ctgtcatatg aagatatgaa agatatttca ttaaggtcag gattatcggg
    10981 aataggtctt tcattaatta gcttatactt ggaggaagat aatgatgact ttttggttac
    11041 ttctgaaaaa attgctgatc agatagaaaa taggattatt gaagatgata aattatcagc
    11101 aactgatttt gcagcagtcc ctataggttt gattgatggt tggtcaggaa tatctttatt
    11161 ctatgcggca ttatattcag ttactaagaa agaaaaatat tatgtaaagt caaaagaata
    11221 cattgagtgg gatttaaaac attgtaaggt agatgaagag acgaatactt tgcaaacgta
    11281 tgatgatcaa aaccctcgat tactacccta tttatcagga ggatcaatcg gaataggggt
    11341 tgctatttgg tatttaaatt atgtaggaaa taataattta tttagagaag aattagagca
    11401 aataatcaat ttaaataaag taagaattgc atatagcggt ggattgtttg atggggtcgg
    11461 tagtttcttg ttaatcccgt caatgactaa ggaaaataat gaaatcagtc agcagattga
    11521 gctggcattg aaaaaactag aattgtttct tatccgcaaa gatgatcaag tattattccc
    11581 tggaaacttc agttttcgtt tagcagatga ttactactcc ggaagtgctg gcataatatt
    11641 gggcataaac tctatccagt tctcaaatcc gttatattgg ttgccaataa taaaaattga
    11701 tagtttctta aataagacta aaaaagaatt gttgttaaac aattaaactc taacacttat
    11761 agttgatgat aatcattgaa gattggaatt aaagcagtta atatacagaa cttacgaagg
    11821 aggtgagaaa agaaaatgaa agaggtgtta gaacttcaac aatttaatga aaaatctgaa
    11881 gtagagcctg cggcatggac tgttactcta acaactattt ctgttacatt atctactatt
    11941 agcaatcatt gctaattgaa gcataatcaa agaaagagta cttgaaagga ggtgaaacca
    12001 aatgaaagat gtattggaac ttcaacaact cagtgaagga tctgacgtag aagcttcaaa
    12061 aggcaaaggt ggcttgctta cgctaatcac aacgatagtt ggcacatcta ctattagcaa
    12121 taactgttaa gggtaattaa gaggggtgga tgaacaaatg aatgaagtac tagagttaca
    12181 acaattgagt aaaggttctg aagtagaaac agctgggtgg acacttctga caacactcat
    12241 cggtacatct actattagca atagttgtaa taaatgataa aaaggagatg aaaccaaatg
    12301 aaagatgtat tggaacttca acaactcaat gaaggatctg acgtagaagc ttcaaaaggc
    12361 aaaggtggct tgcttacact aatcacaacg atagtaggca catctactat tagcaacaac
    12421 tgtggataaa aggccacaca taacaaaaaa gattttctac gtacatcaag tgctgaagta
    12481 ggaacaatgg gtaggcactt ctaacaacac tcattgacat ttactattag caaagttgta
    12541 ataaatgata aaaaggaggt caaaccaaat gaaagatgta ttggaacttc aacaactcaa
    12601 tgaaggatct gacgtagaag cttcaaaagg caaaggtggc ttgcttacac taatcacaac
    12661 gatagtaggc acatctacta ttagcaacaa ctgtggataa aaggccacac ataacaaaaa
    12721 agattttcta cgtacatcaa gtgctgaagt aggaacaatg ggtaggcact tctaacaaca
    12781 ctcattgaca tttactatta gcaaagttgt aataaatgat aaaaaggagg tcaaaccaaa
    12841 tgaaagatgt attggaactt caacaactca atgaaggatc tgacgtagaa gcttcaaaag
    12901 gcaaaggtgg cttgcttaca ctaatcacaa cgatagtagg cacatctact attagcaaca
    12961 actgtggata aaagaccaaa cacactaaaa aagtatgctt ggtcgttata cattatatga
    13021 aagcctgaac aggaaaagga ccccaatcct tttcctgttt ccaaaaaaag gaacaaattt
    13081 agctttcgta taaattcttt tcactatccc atacttcttt tttattgtca atggaaaatg
    13141 aatgaaggga cttagttctt catttatatg tagaactaaa atcaaaaatg ctaaatttat
    13201 aaaatgaaga atggaggaat attaatgaat aatgttttag cattacaaca attaaataat
    13261 agtgccgagg tggaaccgca agtgggacca accataacaa ctattacagt aatacctaca
    13321 atggttatat ccttaataag taattattgc gacaatcatg cttcataata taatgatttt
    13381 agattgacac ttggctaaaa agtattgcag agaaggaaat ggataactaa atggataaag
    13441 tatataaaaa acgaccgtta tataaaagaa gttggtttca aacatttttg gcatttttag
    13501 tatctcagct ttattttaat tttgtagaat taacgggatg gggtcctaag tatagagaaa
    13561 tgaatggatt cccagcaaac atagttgaac tagatttctt tcaaacatat ctttcattct
    13621 atgataatcc atggtttaat attattactg ttttcttggg agttttcact attatacaaa
    13681 taattacagg gataacaaag gatattcgaa attaaagcaa taacttctga tgccttattt
    13741 aatgatgaaa gaaaatgaac actttcttaa ttatcttatg agtgaagact gcgacactta
    13801 gtcagcagtc tattttattg gttctggatc aggattaccg aattataacc ctatacaaat
    13861 atatagtagg ttgccacttg ctgcgttggt tattttctaa atcatgagca aatcccaaat
    13921 ggttcagatt aaagttcttg cattttttta agtaggagtt tattttctct tctcatcctc
    13981 tttactccat gtgattcata agtggtagca agcttaagta gaggtttttt cattctcttg
    14041 agtactcagt tataccaccc ccaactcaat ttgcttaatc aaagtttatc tcttgaatta
    14101 gtttttccgc aaatatgata ttgagatacg gatatggtgt agcgttaaat atcttatttt
    14161 caataacagg acaattattt tgcgttggta atatggagaa ctcatatgat attctattta
    14221 ggttggaata ctatttatcc aaaaagttca aaagtaaggc cactaagaaa gacgaaggtc
    14281 ggcgccagtg ttagccacaa tataaaaaat aggtatagat aatcatccca cgtgaaatgt
    14341 tcaaaattta ctatagattg ataagaaatg ctttcgcatg cgatagtgta aaaaaagcat
    14401 ggtcagtttt tttatattga gataaaggta tagccgtatc ccctaatgaa aggatttgat
    14461 ttttgttatg acagataatt tctggcgtga attaccacgg ccattttttg tactggcacc
    14521 aatggaagat gtgacagatg ttgttttccg tcatgtagta agtgaagcag gcaggccgga
    14581 tgtgtttttt acagagttta caaactcgga gagctattgt cacccggatg ggaaggatag
    14641 tgtgcgcggc cgtttgacct tcacggagga tgaacagcca atggtagctc atatatgggg
    14701 agacaagcct gagaactttc gccaaatgag tattggtatg gcggaactag ggtttaaggg
    14761 tctagatatc aatatgggct gtcctgtacc taatgttgcg ggaaatggaa agggaagcgg
    14821 ccttatttgt cgtccagagg ttgcagcaga actaatacaa gcagcaaaag caggcggatt
    14881 gccagtaagc gtgaaaacta gacttggtta cacggatata gatgaatggc gcgactggct
    14941 gacacacgta ttgaaacagg acattgctaa tctttccatt catttgcgca caagagcgga
    15001 aatgagcaaa gtggatgcgc attgggaact catcccggag attaagaaac ttcgtgatga
    15061 ggtagcgcca gatacactgt tgacgatcaa tggggatatt cctgaccgcc aaactggatt
    15121 aaaacttgct gaacaatacg gtgtcgatgg aataatgata gggcgcggta tttttacaaa
    15181 tccatttgcc tttgaaaagg agccgaaaga gcatagcagc aaggaattgc ttgatctctt
    15241 acggctgcat ctggatcttc atgataaata ttcagcatta gaagcgcgtc catacaagcc
    15301 tcttcctcgc tttttcaaaa tttacctccg cggattccgc ggagcaagtg aattaagaaa
    15361 ccaatgcatg aacactaagt caacagatga agtgcgtgca ttgctcgatg actttgagag
    15421 taagtatctt gatggggtgg agcaacagta gatgtttcct aattcaaggt aaaagcgaag
    15481 cgggacgctc tttttgcttt ataagttagt tatttaggaa atgtttattt tcactgtgca
    15541 aaaaatacaa cagacgaaga ggaatctgtc agatttcctc ttcttttttg attcaataag
    15601 tcagattgtc tgacattcca attgaaccag ctccatataa tcaataaagt aaatgcaaga
    15661 gtttctaaaa cagaatgggg gctggaagca tgatggatga atacgccagt atatataaga
    15721 acgtgattga atggaggaga catcttcatc aatacccgga gctgtccttt caagaagaaa
    15781 aaacagctca atttgtatat gatacgctct cttcttttga aaatcttgag atcagccgcc
    15841 cgacaaggac aagtgtcgtt gcccggctga gcggtgcgcg gccgggcaag cgaattgggc
    15901 tgcgcgctga tatggatgcg ctgccgattc aagaagagca tgacagtcat tttcgctccc
    15961 gccatccagg tgtaatgcat gcgtgcgggc atgatgggca taccgccatg ctgcttgggg
    16021 cggctgagat tttgtctcag aaaaaggatg agcttagcgg cgaagtctac tttatttttc
    16081 agcatgccga ggaggttcat cctggcggag cgcaggaaat ggtgaaggct ggtgttgcgg
    16141 accatcttga tctatgcata gccatccatc tgttttctgc catgccttta ggaaaaatcg
    16201 gactggcatc aggcccggtc acagctaact ctgatcgctt tgatatcacg attaaaggaa
    16261 aaggcgggca tgcctctcag cctgaacagt gtattgaccc gcttgtgatt gcctcacaag
    16321 tcattactca tttgcaaagc attgcctcaa gacatacaga tcctgccgaa agactggtgc
    16381 tctctgttac catgtgtcat gcgggctccg cctacaatgt gatccccgat actgtgacgc
    16441 ttggagggac ggtaaggacg tttcgaaagg aagtccgggc aaatacggaa gcgctcatgg
    16501 aaaccattat aaaaggcgta actgaagccc atggcgcgtc gtatgatttt gattaccgcc
    16561 atggatacaa gtctgtggta aacgatccga acgtaaccga actggtcaga caagcagcag
    16621 agaatctgtg ggggaaggat caggtatttc cgttagcgcc aatgatgggc ggagaggatt
    16681 tctccgcgtt ttctgaacga gtgcctagct gttatatcgc tttgggagcg ggaaccgggg
    16741 agatgatcta tccgcatcac catcctaaat tcacgttcga tgaaaaagcg ttatcagcag
    16801 gtgttaaatt atttgtaaat tcagtctatt tcattctgca ttcccgtgaa tcgatttcaa
    16861 tgaagatcaa ctaaaaccga ttataggagg gcgctatggc taaacatctg ccggaagtca
    16921 tgaccgctga ttctttacaa aaaatcgagc ataaaggaat attaaagtgg atcgaaaagg
    16981 ccggaaacaa attgcctgat ccttttatgt tatttatcta cttatcgatg atcatcattg
    17041 ccatgtctgt tttgctggca ggaaacgcag tgacacatcc gggagacggg aaagaggtag
    17101 ccgttaagag tttgctcagc accgagggca ttcactggat gctgacggaa gcggtgaaca
    17161 actttgttca atttccgcct ctcggacttg tgctcacgat ggtgctcggc atcgggctgg
    17221 cggaacgcgt cggtttgatc gaggctgtgc tgcaaaagat gatggcgcat gttccgaaag
    17281 cgatcatcag ctattccgtc gtatttgtcg ggattttagg gaatctggcg tctgatgcgg
    17341 catgggtcat tatcccgccg gttggcgccc tgatcttcat ggcagccggg cgtcatccgc
    17401 ttgccggctt tgcggccgct gcggcaggtg tagggtcagg attcacggcc aatctgatga
    17461 tcgccgggac agacgcgctt ctttccggca ttaccacaca ggtcgcgcaa accgtcgata
    17521 aaaatgctca ggtatcggct gtcgataact ggtttttcat ggcggcctcc gtatttgttt
    17581 tagcctttat cggtgcatgg gttactgata aaatcgttga accccggctt ggcagctacc
    17641 gcggagaata caagcctgaa atggcggcgt taacgggaaa agagatcaaa gcactgaagg
    17701 cggcgggggc agcggccctt ttatatgctg gagtcattgc gttattagtt gttccagagg
    17761 gagcgctcct gcgtgatcct gaaaacggat cgattctttc ctcgcctttt ttgaaaggca
    17821 tcatccccat cattctgctg ttctttatta ctgtatcggt tgtttatggc atcgtggccg
    17881 ggcgcattaa gaatcagaca gacgtcccga ggctgatggg agattccatt aaaggcatgt
    17941 caggctttat tgtgctcgtc tttgttattt cgcagtttat cgcctttttc acgtggagca
    18001 atatggggat ttttatggca gtaaaaggag cggactttct ggaatccatc catttaacag
    18061 gttttcctgt attaatcgga ttttcgttgc tgacttgtgt cgtcagtctg tttattacga
    18121 gcggctctgc tttatgggcg ctgctggccc ctgtgtttat cccgatgctg atgctgctgg
    18181 attttcatcc cgcgtttatt caaattgcct atcggattgc ggattccgcg acaaacacca
    18241 ttacgccgat gaatccgtat ttgccgatgc tgatggctta ctataagcgc tacaaatcag
    18301 atgcgggctt cggaactgtg atctcaacca tgattccgta tacggttctg ttcttcttgg
    18361 cgtggcttct catgatgttc atttggtacg ctttcggctg gccgatcgga ccgggcgttt
    18421 atgcaaaata aaaacggcaa agggtgggag acatatggat atgattcaaa taagacgaga
    18481 ttttcaccgg catcccgaac tgggcttcac agaatttcgc acagccggaa aggttgtgga
    18541 aactcttcaa gccctgggat atcacgtgac atatggcaag gacgcaatgg atggcgaggc
    18601 ccgcagaggc gttccttcag aaaaagaact gaagcgcgct tttgaccgtg caattgaaaa
    18661 tggagccgat cctgatatca ttgcgccgat gaaaggcgga tataccgctg tcatcggaag
    18721 acttgaaggg aatacgccgg gacccgtcgt tgcgcttcgt tttgatatgg atgcacttcc
    18781 gattacagaa agcgcagatg ctgaccatgg tcctcacgcc aagggcttcc gttctgcatt
    18841 tgaaggaaat atgcacgcat gcgcccatga cggacatacc gcgatcgggc taggcgttgc
    18901 tgaagcgctg gcacatcgaa actttgcagg tactctgaag ctgattttcc agcccgctga
    18961 ggagggtgtc cgcggagcgt atgccgttac tgagaaaggc atgctggacg atgttgatta
    19021 tctcctctgc catcatctgg ggactaatgt gccgcttggg gaagtatacg gcggtgcaga
    19081 aggatttctg gccactacga aaatggctgc tcatttccgg ggcgtctcct cacatgcagg
    19141 agcggctcct gagcatggca gaaatgcttt gctaggggcg gcgacggcgc ttttaaatat
    19201 acatgccatt ccgcgtttca gctcgggcga tacccggatc aatgtcggcg tgcttgaagg
    19261 cggaacagcg gccaatatca tcccgcagca cgcgaaaatg atcattgaaa cgcggtctga
    19321 ttcagaagag gtcaaccgcg atctggaaga gcgggtgaga aagatcaacg cccacagcgc
    19381 agccatgcat gagcttgaac atgaggtcga aatcatcggc ggagcgattc cgatcaaatg
    19441 tgacgaggaa atggtttcga ccgtgctaga agctgctgga gaggttggcg gattttcctc
    19501 actgcaaggc atccagaccg gctcaagagg aagtgaagac gcaagctata tgatcaaaag
    19561 agttcaggag cggggaggaa aagggacata tatgatcatt ggcaccgaca tcgctgcccc
    19621 gcatcatcat gaaaagttcg atatccagga agatattctt ccgcgaagcg ttcagcttct
    19681 gaagcaagcg gcattgaagc tgttgaagta gagggagaat cccctctttt tttatgtcat
    19741 tcgaagcgat ttccaaataa aggagacgat ttgttggatt tatggtacat tgataggtat
    19801 gaaaaaagag gagaatcaaa tgaagagaat gcatttttgt acaggtatag gcctgctgct
    19861 gatcgtgatt tcagcctatc ctatctttgt actattgaga gaaaatataa tagatcacaa
    19921 cgtaacaaat cgttatgaca ttcattatgc atatcaagac aagcaaggtt atgaacctgc
    19981 gatagatact caaaatatca acatatttaa tcatcatatt aggattattg agaccaaaac
    20041 aggaaaacat gcgcccctga caagctggga taaagacgaa aacgtccctg ccggagagat
    20101 tgttaacata cagtatcaat tagacggccg agatctctca tcaccttctg aagtatggct
    20161 ttctaatcga gaaagaggag gaagatactt ttcatggctt gaaatattaa cggtaaagga
    20221 tcgaaagact gatcaaaatc tggtttacat tgttcagaga ataactgacg atcaaataag
    20281 tcttgaaaaa agcaaatgga aaataatcag gattcatcag gatgggactg taaaggagaa
    20341 gcttctaagc tattctgata gaagcaagga tccattgagt gtaaaactgc tcaatttttc
    20401 atacgttgga ggaaattcaa tggggtatca ttctgatatg tatgaagtga ttcccaatgt
    20461 catatttcct cttttgtatc cgttgattac ggtcgctgtt ggttgtgcga tcatgatcgg
    20521 gattttaatc attgtgatag tccagaagat aaaaggagtt cgaaaatcaa tatgaaacga
    20581 ctatgcatca tcccctgcgg cgcgaaaaaa atctgggatg ttcagcctga tgcggggccg
    20641 acgagggcgg aagacgctta cctgagcccg tttcatcagg cgtgcgagcg gtatgcaaaa
    20701 gctttttttg acgagtgggt cattttgtcg gcgaagcacg ggttcctgcg tcctgatgac
    20761 atcgtgccgg aaaactacga tgtggcattc gggagcggtc atccagagat tatgacagag
    20821 gagaagttaa gccgtcaata tcgtgaaaag ggttttcttg aaaaagaaga gctcgtcatg
    20881 ctcggcggga aaaaatatcg taaagtcctg agcacggtcg tcggagatca tcagcatatc
    20941 agctggccgc tggcaccgta caaaggcatt ggttacatgc ttcaggcact gaacagggcg
    21001 gttgaagaaa aacaagaact gtaatacgta cataacccga aaagggtgtg aaaatgaaaa
    21061 gaatggtgtt tggcttcctt gccattgcgg tatgtggaag cggcttttat atctatcata
    21121 ttttattcgg tgatccattt tcaaaaaatg ccgcagagca aaagctcaca tcatatgtga
    21181 aacagaccta tcctcaaaaa gaaatcaaga tcacgaatgg agtttataac gcgaaaacct
    21241 cggaatatgt gtttcaagca aacacccaat ctcaaagcta ctaaatgtgc gcgatagggt
    21301 ttctccatcc taaggtaacc tgcgatggga ttgaagaagc ctataccgag tctgttgcaa
    21361 aacatctaaa tcaagaagca tcaaaggaaa tcgaagcgga tttgaaaaaa gccgttccgc
    21421 aacttataaa agccgaagca gatatcagcg ttgaacacgc tcagtttaca ttagatacaa
    21481 gctggagcaa gcaattggct gaaagagcgc cgctgagttt gacgattcag ttagatgcaa
    21541 gcggaaaaac aaaaacagat gccgtggcga tggcggaaac cgtcagaaaa acgctaaatc
    21601 aaaaagggta tacatatttc agaggcacga tagactgcat gcagaaggat ggggacggcg
    21661 gctttggtta tgtaaaatat tcaattgatt ttactcctga aatcgccatt cagacaaacg
    21721 atgcagaggc attaggaagt tgataa
//
