LOCUS       NZ_JAHVOC010000002     21613 bp    DNA     linear   CON 04-NOV-2023
DEFINITION  Bacillus sp. XT-2 Scaffold2, whole genome shotgun sequence.
ACCESSION   NZ_JAHVOC010000002
VERSION     NZ_JAHVOC010000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus sp. XT-2
  ORGANISM  Bacillus sp. XT-2
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 757568)
  AUTHORS   Wang,X.
  TITLE     Characterization of the facultative-halophilic Bacillus halotolerant
            XT-2 producing multiple lipopeptide biosurfactants and its potential
            for Enhanced Oil Recovery and bioremediation
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 757568)
  AUTHORS   Wang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUL-2021) State Key Laboratory of Microbial Resources
            & CAS Key Laboratory of Microbial Physiological and Metabolic
            Engineering, Institute of Microbiology, Chinese Academy of Sciences,
            1-3 Beichen West Road, Beijing, Beijing 100101, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-MAY-2021
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: GCF_004006435.1
            Genome Coverage                   :: 95.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/04/2023 05:26:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,802
            CDSs (total)                      :: 4,698
            Genes (coding)                    :: 4,533
            CDSs (with protein)               :: 4,533
            Genes (RNA)                       :: 104
            rRNAs                             :: 8, 8, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 7, 8 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 165
            CDSs (without protein)            :: 165
            Pseudo Genes (ambiguous residues) :: 0 of 165
            Pseudo Genes (frameshifted)       :: 95 of 165
            Pseudo Genes (incomplete)         :: 92 of 165
            Pseudo Genes (internal stop)      :: 27 of 165
            Pseudo Genes (multiple problems)  :: 43 of 165
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:21:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 335545
            Orig. end                         :: 357158
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHVOC010000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21613
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="2"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21613
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21613
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11613](-)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11613)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(50..62)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.63"
                     /tool="antismash"
     misc_feature    357..370
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.08"
                     /tool="antismash"
     misc_feature    complement(408..421)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.96"
                     /tool="antismash"
     misc_feature    445..458
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.58"
                     /tool="antismash"
     misc_feature    complement(446..459)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.44"
                     /tool="antismash"
     gene            complement(541..1020)
                     /locus_tag="KXD37_RS07765"
                     /old_locus_tag="KXD37_07700"
     CDS             complement(541..1020)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003235899.1"
                     /locus_tag="KXD37_RS07765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07700"
                     /product="hypothetical protein"
                     /protein_id="WP_061572213.1"
                     /transl_table=11
                     /translation="MKVQFKKRISLLIIMFGLAVSSLGVTQAVHAKANTSDSRVHFTFR
                     WYSPYDYTTARRKQNRSYMYMHLLKKDDGGKFDVWAEADKNVHSGGRDWHNVSGGGTHE
                     GTVHPGHTYLFSNTAVEDYGRNVPVRFGGYSRSNDSFSTDWSPDSVKPKGNYTIY"
     misc_feature    1119..1132
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.35"
                     /tool="antismash"
     misc_feature    1122..1137
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.93"
                     /tool="antismash"
     misc_feature    complement(1124..1137)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.7"
                     /tool="antismash"
     misc_feature    1200..1213
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.74"
                     /tool="antismash"
     misc_feature    complement(1211..1224)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.79"
                     /tool="antismash"
     misc_feature    1233..1246
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.88"
                     /tool="antismash"
     gene            complement(1273..1392)
                     /locus_tag="KXD37_RS07770"
                     /old_locus_tag="KXD37_07705"
     CDS             complement(1273..1392)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391627.1"
                     /locus_tag="KXD37_RS07770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07705"
                     /product="PhrC/PhrF family phosphatase-inhibitory
                     pheromone"
                     /protein_id="WP_010332289.1"
                     /transl_table=11
                     /translation="MKLKSKILLSCLALSTVFVATSIATAPAHQMEVAQRGMI"
     gene            complement(1376..2521)
                     /locus_tag="KXD37_RS07775"
                     /old_locus_tag="KXD37_07710"
     CDS             complement(1376..2521)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="KXD37_RS07775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07710"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_188323349.1"
                     /transl_table=11
                     /translation="MTSVISSSSVGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLENMRIEEQPRLSDLLLEIDKKQARLTGVLDYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKEHTAYNIRLLQCHSLFATNFLDLKQYEDAISHFKKAYTMAESEKQPQLMG
                     RTLYNIGLCKNSQEQYESAITYFKRAISVFEEANILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGIAYSKEAGDIIYLSEFEFLKSLYLSGPDEEAIQTFFDFLESKMMYADLEDFA
                     LDVAKYYHGRENFQKASAYFLKVERVRQLIQGGVKLYEIEV"
     misc_feature    complement(2554..2570)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            2750..4108
                     /locus_tag="KXD37_RS07780"
                     /old_locus_tag="KXD37_07715"
     CDS             2750..4108
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="KXD37_RS07780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07715"
                     /product="YncE family protein"
                     /protein_id="WP_106019735.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAEAAQDCLCFCEEETSREAMFQAPIELPEGFVVD
                     PAEAVANVTWNADSLSCVSERCLIQTGPEPDEIGVQFAVRLQGTVTLLVSVSPVRNQYG
                     QGEGAVSVIHNVEIDQVVYYSDEPDDCPDVSDITIENLVVVPPFYGSPLSVTGTIVLVP
                     APEPEPVYAFTANPDDQSVSVIDTNTHTVVTTISLPYQPTRIEKAPDNTSVFVLHYYDR
                     VISVISQDTLSVTASILLDQPPESISFIPGHEFFYVVAGGAINVIGIETLTVERSIPFE
                     GFDVAIDPNGLFAYLLGFGSVQRLDLNTGEVTGTIERDLIVNALETGWPERYLYVLEQE
                     FFFNYLTVIDLNTFTISSTQELEYEGEYGMFKSGSGVYLFDDFTHNLYSVSPSGAGVIG
                     NLPQSARDFAFTPNGEFLYATNFIEQSITVYNTDDYSVETVISLGVSPSDIAI"
     gene            <4308..4664
                     /locus_tag="KXD37_RS07785"
                     /old_locus_tag="KXD37_07720"
                     /pseudo=""
     CDS             <4308..4664
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="KXD37_RS07785"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="KXD37_07720"
                     /product="YncE family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="VMNGELCRRV"
     gene            complement(4671..5372)
                     /locus_tag="KXD37_RS07790"
                     /old_locus_tag="KXD37_07725"
     CDS             complement(4671..5372)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="KXD37_RS07790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07725"
                     /product="bacteriocin biosynthesis protein AlbG"
                     /protein_id="WP_151174591.1"
                     /transl_table=11
                     /translation="MKKSTVFTLLLLLAAMAAYSFGWFHSGAEAAGQYVQLIKNDAVRL
                     GLLACAASVLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQHRKLCSRYANDVK
                     LLRDSYKGIRQSYVMAAVLYQVIVFGCMFEIVKAVPFSFHTAPAVTMGLAVLLMLYLLF
                     YMRTYLLQLFQHGNLFRKVLVGVLTGAGIWWMLSFTISELLFLITLAAIQQIGSFVYKR
                     FSYRSPASLDL"
     gene            complement(5369..6646)
                     /locus_tag="KXD37_RS07795"
                     /old_locus_tag="KXD37_07730"
     CDS             complement(5369..6646)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="KXD37_RS07795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07730"
                     /product="pitrilysin family protein"
                     /protein_id="WP_127696379.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 5.7e-13, bitscore:
                     44.6, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 2.5e-07,
                     bitscore: 26.4, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKEAFFQQLDEQTDIRYTDKGMKIFRLQFPRAHLRLCNVKTGFG
                     SRDIRLQSETGGRMLPYGTAHFLEHLLFWHNGRNLYSDFFEHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDEQIIAQEKAVITSEIETALLNHRLHYHYQLIQMLS
                     PASPAAVFPAGRKKDIEALTICDLQEAYAAAYQPHRMTLFLIGGPEDAETLLPSQLRLE
                     KRSGSRSDRKIVPACPPLSPKEVKGDLERPEDTWTGIQVGALPGENGLLTLKLYWDIAS
                     RILFHMDSPFFQEIRQTYRLNIQSLSAEVHLSEDGGFLILHSKGAHSSAYIDVASYYIT
                     QQKNRTEAWLEYGKDSLVNAIIYDSDYARKCFEWAAECEQYDCSFLGLYRTIQQMNSHD
                     FLALIEAMVSSHKAVIHVPKKEVMRQ"
     gene            complement(6652..7815)
                     /locus_tag="KXD37_RS07800"
                     /old_locus_tag="KXD37_07735"
     CDS             complement(6652..7815)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="KXD37_RS07800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07735"
                     /product="insulinase family protein"
                     /protein_id="WP_106019944.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 8.5e-06,
                     bitscore: 21.4, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLTTDQFSTISIAASFLKPIESAAEPEEETIYFYGAAAHQK
                     QNIINTFGYAAGRRFMYSANLFFDRQLKTYGTRMIHPLYAEGFHTDAVLNTFVDMSSFP
                     ASLSASAAEKAKAELLLKMEKTFADPFSYSAARLAEEAFGNPMYGTAMFGRKDKLMAVH
                     PKRFLDASEFIADLFSQQKKLNILGNIQSCDVQGHAPQASAMSAVRKPVNQDIFETETR
                     STAGPSVMTLGFDCGDMKDVRDYLAIQLIDGLLGKYGHSALFRHFREKDLAVYHVITRY
                     DIMSNMLLVSVCTDQLHENEIPPRVLEAVSRFHADEPELKKAQQFLINEILLQFDSPEG
                     LLAYMGILRRFSCKKEDLLDSISAVTCRDLLQFIKNLTYIGAHVVRG"
     gene            complement(7805..9118)
                     /locus_tag="KXD37_RS07805"
                     /old_locus_tag="KXD37_07740"
     CDS             complement(7805..9118)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="KXD37_RS07805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07740"
                     /product="bacteriocin biosynthesis protein AlbD"
                     /protein_id="WP_188323348.1"
                     /transl_table=11
                     /translation="MNNLFPILSLLFKQLYGRQGKKDAIRITAGLAVLALFEIGLIRQA
                     GIDESTLGKTYITLALLFMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSAVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLYWLGRFSFFTVYSIIFGVLLSNLFVKKRR
                     TALLLHAAAFTCVCFSAALMPAVTIPLCAIHMLWAIVIDFPSFLQAPQQQSKMHSFMRT
                     SEFSFYKREWNRFISSKAMLLNYIVMGAFSGFFSFQMMNTGIADQHVVYIVISALLLIC
                     SPIALLYSLEKNDRMLLITLPIKRRTMLWAKYRFYSGLLAGGFILIAMIMGLISGRPIS
                     LLTFLQCMELLLAGAYIRLISDEKKPSFSWQTEQQLWSGFSKYRSYVFCIPLFLATLTG
                     TVISLAVIPIAGLIIVYLLQKQDGGFFDTSGKRERLGS"
     gene            complement(9111..9830)
                     /locus_tag="KXD37_RS07810"
                     /old_locus_tag="KXD37_07745"
     CDS             complement(9111..9830)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="KXD37_RS07810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07745"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_106019731.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYEQDNVILENVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGHFTLCGIEADAGMPQKTSDELKIRRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFNSLAEEFHFSQYTNRRISELSLGNRQKVVLMTGLLLGAPLFILD
                     EPLVGLDVESIEVFYQKMQEYCKAGGTILFSSHLLDVVQRFCDYAAILHHKQIRKVIPI
                     REETDLRREFFEVIGHE"
     gene            complement(9827..9988)
                     /gene="albB"
                     /locus_tag="KXD37_RS07815"
                     /old_locus_tag="KXD37_07750"
     CDS             complement(9827..9988)
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="KXD37_RS07815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07750"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_059292334.1"
                     /transl_table=11
                     /translation="MSPAQRKMLLYILSFIFVIGAVVYFVKSDYVFTLISIAIAIIFGM
                     RARKADSR"
     gene            complement(10001..11347)
                     /gene="albA"
                     /locus_tag="KXD37_RS07820"
                     /old_locus_tag="KXD37_07755"
     CDS             complement(10001..11347)
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="KXD37_RS07820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07755"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_044159802.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1073.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 1.5e-29,
                     bitscore: 97.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 7.7e-09, bitscore: 31.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 7.5e-08,
                     bitscore: 27.9, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 4.1e-45, bitscore:
                     149.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.6e-07, bitscore: 25.8,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.1e-21, bitscore: 71.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.4e-10, bitscore:
                     37.0, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.8e-09, bitscore: 33.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYMRDNVSISDFEYLDLN
                     KTAYELCMLMDGQRTAEQILEEQCAKYDESPEDHKDWYYDMLSMLLNKQVIQLENRARF
                     HKIATSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIDQFKKTADMLYDN
                     GVLTCEITGGEIFVHPNANEILEYVLKKFKKVAVLTNGTLMRKESLEMLKAYKQKIIVG
                     ISLDSVQSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFDSPLVHKLWKAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        complement(11054..11332)
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KXD37_RS07820_Subtilosin_rSAM_RRE.1"
                     /evalue="5.50E-31"
                     /identifier="RREFam018.1"
                     /label="KXD37_RS07820"
                     /locus_tag="KXD37_RS07820"
                     /protein_end="98"
                     /protein_start="5"
                     /score="97.8"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYMRDNVSISDFEYLDLNKTAYE
                     LCMLMDGQRTAEQILEEQCAKYDESPEDHKDWYYDMLSMLLNKQVIQL"
     gene            complement(11482..11613)
                     /gene="sboA"
                     /locus_tag="KXD37_RS07830"
                     /old_locus_tag="KXD37_07760"
     CDS             complement(11482..11613)
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="KXD37_RS07830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07760"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 1.7e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       complement(11584..11613)
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="KXD37_RS07830_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(11482..11583)
                     /prepeptide="core"
                     /locus_tag="KXD37_RS07830_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[11583:11613](-)"
     misc_feature    complement(11704..11719)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     gene            11925..12353
                     /locus_tag="KXD37_RS07835"
                     /old_locus_tag="KXD37_07765"
     CDS             11925..12353
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="KXD37_RS07835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07765"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_024123211.1"
                     /transl_table=11
                     /translation="MKQETPITIHVKSVIEDDGNEEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLGEEQGRISIAYDMHVGDEQQHLHNMTITYEGGTHA"
     gene            12350..14020
                     /gene="argS"
                     /locus_tag="KXD37_RS07840"
                     /old_locus_tag="KXD37_07770"
     CDS             12350..14020
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="KXD37_RS07840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07770"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_254517923.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIRAAVLKAGLAEESQIPNVILETPKDKTHGD
                     YSTNMAMQLARIAKKAPRQIAEEIVASFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGDAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLAKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIISIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRVDLENFRVPFDVWYSETSLYQNGKIDKALDALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLVNVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIDE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEERGLKP
                     AADLDFSPIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     misc_feature    complement(14056..14069)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.38"
                     /tool="antismash"
     misc_feature    complement(14057..14070)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.87"
                     /tool="antismash"
     misc_feature    complement(14058..14071)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.45"
                     /tool="antismash"
     misc_feature    complement(14062..14077)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.43"
                     /tool="antismash"
     misc_feature    complement(14074..14089)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            14154..15341
                     /locus_tag="KXD37_RS07845"
                     /old_locus_tag="KXD37_07775"
     CDS             14154..15341
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="KXD37_RS07845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07775"
                     /product="nitrate/nitrite transporter"
                     /protein_id="WP_024123209.1"
                     /transl_table=11
                     /translation="MINRQHFQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARIIFMISFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAITTFAAPVIAQAAGWKSTVQ
                     MYMALLALFALLHFFFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEQFDLSPADAGLRTAGFIAVSTLLRPAGGWLADKVSPLRILMFVFAGLTLS
                     GVILSFSPTIGIYAFGALTVAVCSGIGNGTVFKLVPFYFSKQAGIANGVVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVIVIWMYWQERMKTHTERSGHSVN"
     gene            15452..16168
                     /locus_tag="KXD37_RS07850"
                     /old_locus_tag="KXD37_07780"
     CDS             15452..16168
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="KXD37_RS07850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07780"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_101864901.1"
                     /transl_table=11
                     /translation="MNFLSVRTSDKDLISSDLHQLLESISTKRKIEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTADGKDLTLRICQKNDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKSRLEKELIHNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VNRSDGILINIALTNQDLAKFCAAARESVNRMLGDLRKQGVISIEDSGKIVLHQRDYLR
                     CEIECENCPLEICNID"
     gene            complement(16201..16920)
                     /locus_tag="KXD37_RS07855"
                     /old_locus_tag="KXD37_07785"
     CDS             complement(16201..16920)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="KXD37_RS07855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07785"
                     /product="YwiC-like family protein"
                     /protein_id="WP_106019729.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFCLGMVKGGAVLWHIPLFLGWLFLYLA
                     VYPVTLALKKKQIKPYQKWIISYSFPACSFLLAAVIHKPSFIWLAFSLLPLFLIHVYYA
                     RLKNERALLNDFAGVLFFCTGGLASCWLGTETLDGWAWFIFAQSALFFIGSSFYVKSVI
                     REKNNRVFAYWSWGYHLILPLLSAALGGGWAVLAFIPSSLRAWFFHGKKWPVQTIGILE
                     IVNACFFFAIMCIWLTR"
     misc_feature    16991..17006
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            17064..17540
                     /locus_tag="KXD37_RS07860"
                     /old_locus_tag="KXD37_07790"
     CDS             17064..17540
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="KXD37_RS07860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07790"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_024123206.1"
                     /transl_table=11
                     /translation="MNQCDYLFFLKQLPMFNEVPLSIVETLLNNGTFIRGSCDQDPSFL
                     HSQSIYIVLKGSIRFIDSRLPEGSQTVALWEKGDVFPIDQKGGMFLSPFISVRTSEDIL
                     MLNIPFYILKKIMSYYPQLQMNFLVMLQQNVFFSYELFLRYMHRSQDENAEPDS"
     misc_feature    complement(17615..17630)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            17696..21382
                     /locus_tag="KXD37_RS07865"
                     /old_locus_tag="KXD37_07795"
     CDS             17696..21382
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="KXD37_RS07865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KXD37_07795"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_263463464.1"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHQSNKHSQTTYEDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRSVLINLWREALQAHQNPLEAWKSIVENPDKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVITYGPDRNIGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQKTERFIEYAKQYTD
                     FPFFVTLTKEDGVYTAGRFLHAKDIGRQTEHDQWKPAVWNERTSAFAIPQGTIGSRWDG
                     QKKWNLHMIDEETGESIEPRLSVLGIEDEIGTVRIPYFSNEGNRVLERDLPIKKLALDN
                     EDVYVTTVFDLILANYGVNRGIGAKSACSYDDPEPFTPAWQEQVTGIKKEMVINIAREF
                     AQNAIDTEGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIANAKDWEGAPKLQNGTSFFYFATDQWRYEDQPVSDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFDKNGIDLYKEAEKAGAKTTKDVADYVARQLQEKKLKFAIEDP
                     DNEANFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDASDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSNLAEEVDMKPVKEAVAAPLLHDTMQEMAQPLGKIKDWSKGECEAV
                     PGKTMPNIQVVERDYKQIFHKMTALGPNAALKPSGTKGMSWSIADEYESLKKRLGEVTT
                     DSVAKGCPNISEAKQAAEAVLTLSSTSNGKVAVKAWESLEDITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAADTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    21460..21474
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
ORIGIN
        1 agcaaataaa gatttaataa taatggtaag ataatgacga aaaacgaaat tgcaaagttc
       61 aatccgaata atactgtgaa gtatttcttt ttagttgttt ttgttataac gttcataaga
      121 aatccagtat ttttatcttc acagtacata ccggacattg gaagtgatgc taataaagga
      181 agaatgagaa tccagacagt ctgagctgag gttgtgtttc cttctgcaat attcgataaa
      241 aacggtgagt tatggatttc ataaggaaga ttgatcttct tatgaaagaa gagaatacct
      301 agataactga cgagcataag aacgatacta atgaataaag agaaataaat ctctttattt
      361 tttaataaac gctttaaaaa gaaagaaatc atgtgcaagg ctcctgtttt ttattaaaac
      421 tctatgtgag ttttggatag ttttatttta ataaaaaatc tttaagagtg gatattattt
      481 ttaccttaaa aagcgatctt acatgtttag tgtaagatcg ctttgttttg aaaaagggta
      541 ttaatagatt gtgtaatttc ccttaggttt tacgctgtca ggactccaat cagttgagaa
      601 ggaatcattg ctgcggctat aaccgccaaa ccttacgggt acatttctgc cgtaatcttc
      661 aacagcagtg ttggaaaata agtatgtatg acccgggtgt actgttcctt cgtgagttcc
      721 accaccggat acattgtgcc agtcgcgccc gccagagtga acgtttttat ctgcctctgc
      781 ccatacatca aatttgcctc cgtcatcttt ctttaggaga tgcatataca tgtagcttct
      841 attttgtttt cttcgagcag ttgtatagtc gtaagggctg taccatctga aagtaaaatg
      901 cacccttgaa tcgctcgtat tggcttttgc atgaaccgcc tgtgtaacac ccagtgagga
      961 aacagcaagc ccaaacatga tgatgagtaa actaatcctt tttttgaatt gaactttcaa
     1021 aataaatcct ccattttaac cttcaattga agttgtactg aacttaagtc ttgtatataa
     1081 taattcaata aaaaggaaaa gtaaacaggt ttttcattta taattataaa aattatctta
     1141 tatattatgt ttctggattg ggaaaccaat ttaaaataat ttagtaatta atattttaaa
     1201 ttttaaaaac aaaacttttg ttttggcttt ttatttaaca aaaaaacaac cggtaaaaac
     1261 cggttgttat ctttaaatca ttcctcgctg agcaacttcc atttgatgtg caggtgcagt
     1321 tgcaatactt gttgcgacaa acactgtgct tagggccaga caagagagta atattttaga
     1381 cttcaatttc atacaatttc actcctcctt gaataagctg tcttactcgt tccaccttca
     1441 gaaaatacgc ggaagctttt tggaaatttt cacgtccatg ataatatttt gccacatcaa
     1501 gcgcaaaatc ttcaagatca gcatacatca ttttactttc gagaaaatcg aagaatgttt
     1561 gaattgcctc ttcatccggg ccagataagt ataaagattt caaaaattca aactctgata
     1621 agtatatgat atctccggcc tctttagagt aagcaattcc tttactatga tattcatgag
     1681 ctttatccat ttttcctaat ttataatgaa tttgtgtaat caaaaaataa gcttgtggca
     1741 gagaaggaag aatgttagct tcttcaaaaa cggatatggc tcttttgaaa tatgtgattg
     1801 ctgactcata ctgctcttgg ctgtttttgc aaagcccaat gttgtacagc gttcttccca
     1861 ttaattgggg ctgtttttcg gattcagcca ttgtataagc ttttttgaaa tgtgatatgg
     1921 cgtcctcata ttgcttgaga tctaagaaat tggtagcaaa caaagaatga cattgaagca
     1981 atctaatatt atatgccgtg tgctctttat atatttcata tgcctgccgt gcatagtcca
     2041 tggaaaaata cgtttgtttc atatagtaat aagattcaga cattttaaag aaaaactcag
     2101 ctttttctat tcgatccttt acaaaaatca gcttgctttc ggcttttttg aaaaatttaa
     2161 tagcagacaa gtactcccgc tggtccagtt cgtacatgcc cctgaaaaaa ttaaagtaat
     2221 aatcaaggac tccggttaaa cgagcctgtt ttttatcgat ttcaagcagc aaatcggaca
     2281 gtcgtggctg ttcctctatc cgcatgtttt ctaacggttc aagatactca agcatcagat
     2341 tgtgccggaa ttccatcagt gaataataca aatgaagatc ctggtcttct tccatttgat
     2401 ccagctcttg tttgatttct cttcgtaaat attccgcatc tggtatgctg aatcggcgta
     2461 tgtacatata ccattcatta atcttttctc caacggaaga agaagatatg acacttgtca
     2521 cgtttgaaaa tccctccctt cattattcta tatatgtcat attttatcat catcattctt
     2581 gtgagaagcg caaaaaaacc gcaatctttt ctttcgttac accgcatgat ggccggaatt
     2641 tcttcaaaaa cagcttttac cctcggctgt ttgtacaagc aaatacattc accttccata
     2701 ttctgttgta tctgcgtgag cagtgtatgt ctgaaaagga agtgatgaaa tgaggaaaaa
     2761 caagctttcc tttaaagaaa aagcagaagc tgcacaagat tgtttatgtt tttgtgagga
     2821 agaaaccagt cgtgaagcca tgtttcaagc gccgattgaa ttgcctgagg ggtttgtcgt
     2881 tgatccggct gaagctgttg caaacgtcac gtggaatgca gacagccttt cttgtgtcag
     2941 tgaacgttgc ttaattcaga cggggcctga gcctgatgaa atcggtgttc aatttgcagt
     3001 acgcctgcag ggaaccgtta cgcttcttgt cagtgtctca cctgtgcgaa accaatatgg
     3061 acaaggggag ggggctgttt ctgtcattca caatgtggag atcgatcaag ttgtctatta
     3121 ttctgatgaa ccggatgatt gtccggatgt cagtgacatt acgatcgaga accttgttgt
     3181 cgtcccgcca ttttacggca gtccattatc ggtgacggga acgattgtgc ttgtacctgc
     3241 gccggagccc gaacccgttt atgcgttcac agcgaatcca gatgatcagt cggtttctgt
     3301 gattgatacc aacactcata ctgttgtgac gacgatttct cttccatacc aacctacaag
     3361 gatagaaaag gcgccagata acacctctgt gtttgttttg cattactatg atcgtgtcat
     3421 ttctgtcatc agtcaagaca cattgagtgt tacagcttct attttgctgg atcagccgcc
     3481 ggaatccata tcttttatac ctggacacga atttttttat gttgtcgctg gtggtgccat
     3541 aaatgtgata ggaattgaaa ccttaactgt tgaaaggtct attccttttg aaggctttga
     3601 tgttgcaatt gatccaaatg gattgttcgc gtatctgctt ggtttcggtt cagtgcaaag
     3661 attggactta aacacaggtg aagtgacagg aactattgaa cgggatctta tcgtaaatgc
     3721 cctagaaacg ggttggcctg aacgttacct ttatgtatta gaacaagaat tctttttcaa
     3781 ttatttgacg gtgattgatt tgaatacatt tacgatcagc agcacccaag agctggagta
     3841 tgagggtgaa tatggaatgt tcaagagcgg atcaggggtg tatttgtttg atgatttcac
     3901 tcacaatcta tattccgtca gtccaagtgg tgcaggcgta ataggaaatc ttccgcaatc
     3961 ggcaagagac tttgcgttta cgccgaatgg cgaatttctg tatgcaacaa attttataga
     4021 gcaaagcatc actgtttaca acacggatga ttattctgtg gaaactgtca tatcgcttgg
     4081 cgtttcaccg agtgacattg cgatttaatc aactgtatat tgtgcatttc taaaagggat
     4141 gagaaatcat gaaaaagaat gatctttctg ttttacagga aaattgtttc tgtttttgtg
     4201 atgaagatgc cagcagtgaa gcgctatttc aagtgccgat tgaagttccg gaggggtttg
     4261 ccgttgatcc tgcggaagca gtcactgcgg ttacatggag tacagacgtg atgaatggtg
     4321 aactgtgccg aagggtgtaa cagatatcag tttgtcaccc ttgagcaggg gaggtgactt
     4381 tgaccgtcta tttgaaactt tgaggacaat tgtattttct ctggatagta ctagggctta
     4441 ttttctagag ccttatagtg aaccgtttct cattaacaat gtatatgtcg ttaatactgc
     4501 cgcacaaagg atcatcgcaa acgtgtctct tcctaatgtc tatgacctta cagtaacgcc
     4561 cgacaaagcc cggcgacaat gcagggaccg tgtacagcac gagtgatgat tcagccgtga
     4621 cggtcattcc ggttggcgcc ggtccgtcct cgattgcaat gtagatgttt ttatagatcg
     4681 agagaagcag ggctgcggta agagaatcgt ttataaacaa aagatccgat ctgctggatg
     4741 gcagctaagg tgatcagaaa cagcagttca cttatagtaa aactgagcat ccaccaaatc
     4801 ccggctcctg tcagcactcc caccagcact tttctgaaca ggtttccgtg ctgaaaaagc
     4861 tgcagcaagt acgttcgcat ataaaacaat aaatacaaca tcagtaacac cgcaagcccc
     4921 attgtaacgg caggggcagt gtgaaagctg aagggaacgg cctttacgat ttcaaacatg
     4981 cagccgaaaa cgatgacctg atacaataca gcagccatca catatgattg gcggatgccc
     5041 ttatagctgt cgcgcagcaa ttttacatcg ttggcataac ggctgcacag cttgcgatgc
     5101 tgaaagtcac agcagctttg atgagactgt gtgagtttct gaaaagctgc tgtcatgttt
     5161 ttgacagatt gcgtcacgta gtgaagatac aaaaaggcgg gcagcatcag tacggaagct
     5221 gcacaagcca acagcccaag gcggacagcg tcatttttga tcagctgtac atattggccc
     5281 gcggcttcgg cacctgagtg aaaccagccg aaggaataag ccgccatggc cgcaagcagc
     5341 aataataaag taaagacagt gctttttttc attgtctcat cacttctttc ttgggtacat
     5401 gaatgactgc tttgtgagaa gaaaccattg cttcaatgag agccaagaaa tcatgagaat
     5461 tcatctgctg aatggtgcgg taaaggccga gaaacgagca atcgtactgt tcacactctg
     5521 ccgcccattc aaagcattta cgcgcgtaat cactgtcata gatgatcgcg ttgactaaag
     5581 aatccttgcc gtactcaagc caggcttcgg tacggttttt ctgctgcgtg atatagtagg
     5641 atgccacatc gatgtatgcg gaagaatgcg cccctttact gtgaaggatc aaaaagccgc
     5701 catcctctga taagtgaact tccgctgata ggctttggat attcaagcgg tacgtttgcc
     5761 ggatctcttg aaaaaacggc gaatccatgt gaaacaggat gcgagaggca atgtcccagt
     5821 acagcttcaa ggtcaaaagt ccgttttctc ctgggagcgc cccgacttgt attccggtcc
     5881 aagtgtcttc cggccgctcc agatcaccct ttacctcttt tggtgagagg ggagggcacg
     5941 cagggacgat ctttctgtca gagcggctgc cagaacgctt ttccagcctc agctgagaag
     6001 gcaaaagagt ttccgcatct tctgggccgc caatcagaaa cagcgtcatc cgatggggct
     6061 ggtaggcggc agcataggct tcctgcagat cacagatcgt cagagcctca atgtcttttt
     6121 ttctgcctgc ggggaagact gcggctggtg aggcaggaga cagcatctgg atcagctgat
     6181 aatggtaatg aagccggtgg ttgagaagcg ccgtttctat ttcacttgta atcacggctt
     6241 tttcctgagc aatgatctgc tcgtcaaacg agtggttcca taaagcgtca agcaggattg
     6301 gaatggtttg tctgagccga tccggcaatg aggtaaacat gaaatttgta tcagtgtaag
     6361 tggtgaacgc atttaacagc gcgccgtgtt caaaaaaatc actatacagg ttccgtccgt
     6421 tatgccaaaa gaggagatgt tctaaaaagt gcgctgtgcc atatggcagc atccggccgc
     6481 cggtttctga ctgtaaacgg atatcccggc ttccaaagcc ggttttgaca ttgcacaatc
     6541 ttaaatgggc gcggggaaat tgtaacctga atattttcat tcccttgtct gtgtatctga
     6601 tatcggtttg ttcatccagc tgttgaaaaa aggcttcctt ttccatatct ctcatcccct
     6661 tactacatga gctccgatat atgtaagatt tttgatgaat tgcagcaaat cgcggcacgt
     6721 gaccgctgag atgctgtcca gcaagtcttc ttttttgcaa gagaaacggc gcaggattcc
     6781 catataggct aagagtcctt caggagaatc aaattgcagc aggatttcat tgattaaaaa
     6841 ttgttgtgcc ttttttaatt ccggttcatc cgcgtggaaa cgcgatacag cttccaaaac
     6901 tcttggagga atctcgtttt catgaagctg gtcggtgcat acggaaacaa gcagcatatt
     6961 gctcatgatg tcatagcggg tgatcacatg ataaacggcc agatcttttt cgcgaaaatg
     7021 ccgaaataaa gcggaatggc cgtacttgcc gagcaatccg tctatcagct ggatggctaa
     7081 ataatcgcgg acatctttca tgtctccgca gtcaaagcca agtgtcataa cggacggacc
     7141 tgctgtgctg cgtgtctctg tttcgaaaat atcctgattc acgggttttc ttacagcaga
     7201 catggcagac gcctgtgggg catgtccctg aacatcacat gactgtatgt ttcctaatat
     7261 gttcagcttt ttctgctgag aaaataaatc agcgataaat tccgacgcat ccagaaaacg
     7321 tttaggatgc acagccataa gcttgtcttt ccggccaaac atggcagtgc cgtacatcgg
     7381 gtttccaaag gcttcctccg ccagacgggc tgctgaatag gagaacgggt cagcgaatgt
     7441 cttttccatt ttcagcagca gttcagcttt tgccttttcc gctgcgctgg cagaaagaga
     7501 agccggaaag gaggacatgt caacaaaggt gttcagaacg gcatctgtat gaaatccctc
     7561 agcatataac ggatgaatca tgcgggtccc gtacgttttc agctgccggt caaaaaagag
     7621 atttgctgaa tacatgaagc ggcggccggc ggcatagccg aaagtgttga tgatgttttg
     7681 cttctggtgt gcagccgcgc cataaaaata gatcgtttct tcttcaggtt ccgccgcgct
     7741 ttcgatcggc ttcagaaagc tcgcggcaat cgagatggtt gaaaattgat cagtcgtcag
     7801 caggttaact tccaagtcgt tctctttttc cgcttgtatc aaagaaacca ccatcctgtt
     7861 tttgcagtaa atagacaatg atcagcccgg caatcggaat gactgccaag gaaataacag
     7921 tgcctgttaa agtagctaaa aaaagaggga tacaaaatac ataggaacgg tatttagaga
     7981 aaccgctcca gagctgctgc tccgtctgcc agctgaagga cggctttttt tcatctgaaa
     8041 ttaaccgaat ataagcccct gccagcagca attccataca ctgcaaaaaa gtcaaaaggg
     8101 aaatcggccg gccgctgatc aagcccataa tcatggcaat caaaataaac ccgccggcca
     8161 ataaaccgga ataaaagcga tatttcgccc aaagcatcgt tctgcgttta atcggaagcg
     8221 tgatcagcag catccggtca tttttttcaa gagaatacaa taaagcaatc ggtgagcaga
     8281 tcagcaggag agcgctaatt acgatataga cgacatgctg atcggcaatg ccggtgttca
     8341 tcatctgaaa cgaaaagaag ccgctgaatg cccccattac gatataattt aacagcatcg
     8401 ctttggagga aataaaccgg ttccattctc ttttataaaa cgaaaattct gatgtccgca
     8461 taaaagaatg cattttgctc tgctgctgag gcgcctgcaa aaatgaaggg aagtcaatca
     8521 caatagccca gagcatatga atcgcacata gcgggatcgt cacggcaggc atcaaagccg
     8581 cactgaagca cacgcaggta aatgccgccg catgcagcag gagtgccgtt ctcctttttt
     8641 tgacgaaaag attgcttaac aaaacgccga aaataatcga atagacagta aaaaacgaaa
     8701 atctgccgag ccaatacagg gtttgtgctc ctgacagcgt tccgtttccg aataagaaca
     8761 gcggtaatat gaaaaaaaac agcgtccttc tcaagcaagt atcaacaaac aaaaccgcac
     8821 tctgagcgag ccagaagctc cgggaagaga tcggcaatag acagctcagc ttcatgtaag
     8881 attccttcca ttgggatgta acagagagaa acaccatgta cgcattcata aacagaagcg
     8941 cgagcgtgat gtatgttttt cctaaggttg attcatcaat gcctgcctgg cggatcagcc
     9001 cgatttcaaa caaggccaaa acggcaagcc ctgcggtgat gcgaatggcg tctttttttc
     9061 cttggcggcc gtaaagctgt ttgaacagca atgacagaat cggaaacagg ttattcatgg
     9121 ccgatcacct caaaaaattc acgccgaaga tcagtctcct ctctaatcgg aatgaccttc
     9181 cggatctgtt tgtgatgaag aatggccgca taatcacaaa atctctgcac cacgtcgagc
     9241 aaatgggaag aaaacaaaat cgttccgcct gccttgcaat actcctgcat tttctgataa
     9301 aagacctcta ttgactccac atctaagccg acaagcggct catccaaaat aaacagggga
     9361 gccccgagca atagcccggt catcaacaca accttttgcc tgttgccgag ggacagctcg
     9421 gaaattctcc ggtttgtgta ttgggaaaag tgaaattcct ctgccaaact gttaaattgc
     9481 tgctctgaga aatctttctg atacaaagaa tgaacgaaag aaacatagtc cttcgccgta
     9541 atttctgtaa atagaagcgg ataatcggca gcaaagtagc ggcggatctt cagctcatct
     9601 gatgttttct gcggcatgcc ggcgtccgct tcaatgccgc acagcgtaaa gtgcccgctg
     9661 aaattgcggt ttacccctgt cagcgtattg atcagcgttg tttttccggc gccgtttacc
     9721 ccaagcagtc cgtaaacggc gcctttttct aaatgtaaat ctacgttttc taagatgacg
     9781 ttgtcttgct cgtaccacac ggatacatcg tgtatatcca aaatgctcat cgcgagtcag
     9841 ccttccgcgc gcgcataccg aaaataatgg cgatggcgat agaaatcagc gtaaacacat
     9901 aatcgctttt tacgaagtag acgaccgcgc cgatgacaaa aataaatgaa aggatataca
     9961 gtaacatttt tctttgtgct ggtgacaaat tgtttccctc ctaaataagc tggaccacat
    10021 cttctaattg ttcatttttc gcccaggagc agatgttttt tctgtggtat ttgttggagt
    10081 tcagcccttt taagtaacag cctccgcaat agccgctgaa cgggcatttg tctttcatgc
    10141 aatgctcgct gaaccgcggc gcctgcgctt tccacaattt atggacaaga ggggagtcaa
    10201 agatgctttc atatgaatca tgaaatatat ttcccaatga aaattccttc gggaagagtg
    10261 cgcacggtcg tacttctccg aacgggctga tcacaattga tttccagccg gcgccgcagt
    10321 tcgccgcacg ttttctttca tacggaatga tcgggatcaa atctttaaat tcatcaatga
    10381 cattttgctc gtactccata aatttgcggt gctgttcggc atctttcgtc ggatggacaa
    10441 tatctctgcc tcttccgaaa tcatcaaccc aattgtaaga gaacgctttc gccccgagat
    10501 cgcgcacctt ttgggccata tcgtggattt cccacatgtt tttttcgaaa accgacatgg
    10561 cgactctgac aaaaatacca tgatcactca acaattttat cgttttacag gtttgggcaa
    10621 aagagccttt tctccctcta aatgaatcat gcacttcgga ctgtacgcta tccagtgata
    10681 tgccgacgat gattttttgc ttataggctt ttaacatctc caggctttct tttcgcatca
    10741 gcgttccgtt ggttaagacg gcgacttttt tgaatttctt taacacatat tcaagaatct
    10801 cattggcgtt tggatggacg aaaatttcgc cgcctgtgat ttcacacgtt aaaacgccgt
    10861 tatcatacag catatcagcc gttttcttaa attgatcaat ggatacggtg ccgagcgctt
    10921 ccggcgagct ttctaaatag cagtgggcgc actttaaatt gcagcggtgc gtcagctcaa
    10981 aggtggcatg cagcggcatc ggaaattcat tgcttccgct ggtggcgatt ttgtgaaagc
    11041 gggcccggtt ttcaagctga atgacctgct tgttcaaaag catgctgagc atgtcatagt
    11101 accagtcctt atggtcttcc ggcgactcat catactttgc gcattgctct tctaaaatct
    11161 gttcagccgt tctttgaccg tccatcagca tacaaagctc gtaagccgtt ttgttgagat
    11221 ctaagtattc aaaatcagag atcgagacgt tatcacgcat gtagtcaatt tccagcacac
    11281 cgccctcagg caactggtgg actcttacac tttcattaat aaatggaaac atctgctcta
    11341 taaacaaaat accatcccct atacatatga ttcaaatata aaaatcactg tgtatgtata
    11401 accaagatgt agattttagt taaaatttgt attttagtta aaaagggcat agtaatttac
    11461 tatgcccttt tccggagaac cttatcccca gagaccgaat agacctgttg caccggcaat
    11521 ttcaaaatca gggataggtc cgtccactaa acaagcggct ccgattgaac atgtcgcgca
    11581 acctttgttt tctacaatga cagctttttt cataattgaa tcctcccttt ttttgttttt
    11641 ctagcagatc tttgatgtac ttttatatta aaactatcaa attaccattt caatacatat
    11701 attttgaaga aaatgtgaat tgtaaacggt agaattcgga aaaatgtaat atttcctaaa
    11761 ggtaatcagt ggtatgattt tctcttctat aaaggaattg ctttttctga ggtttatctt
    11821 caaatctgat gagcaatgat ggtaagatag aagcagttga agtttacaaa ccgaatgatt
    11881 atactattca agtcaaagtg gaaagatgaa aaggacgtgt cagaatgaag caagagacac
    11941 cgataacaat ccatgtgaaa tctgtgatcg aggatgacgg aaacgaagaa gtgatcgaat
    12001 tccgcactac cggattttac tatgtgaaac agaataaagt gtatctatct tattatgaag
    12061 aacacgactt aggcaaagtg aaaacgattg taaaagtaag cgaaggcgaa gtgcttgtta
    12121 tgagatcagg cgctgtcaaa atgaaccagc gtttcgtaac tggagcttcc acaatcgcca
    12181 aatataaaat gtcatttggt gagcttgagc tgaaaacgag cacaaaatcg attcaatctg
    12241 atctcggcga agaacaaggc cgtatcagta tcgcatatga tatgcatgtc ggagacgagc
    12301 agcagcattt acataatatg acgatcacgt atgagggagg aactcacgca tgaacattgc
    12361 ggaacaaatg aaggacgtgc tgaaagaaga aatcagagca gccgttctga aagcgggact
    12421 ggctgaagaa agccagattc caaatgtcat tttagaaaca ccgaaggata aaacacacgg
    12481 cgattattca acaaatatgg cgatgcagct cgcgagaatc gcgaaaaaag cgccgcgcca
    12541 aatcgctgag gaaattgtcg cttcttttga taaaggaaag gcttctattg aaaagcttga
    12601 tatcgccggt cctggtttta tcaatttcta tatgaacaat caatatttaa cgaagctgat
    12661 cccgtctgta ttggaagcgg gagacgcgta tggagaaaca aacatcggaa acggcgaacg
    12721 cgttcaagtg gaattcgtat ctgcaaatcc gacgggggac cttcacttag gccacgcgcg
    12781 cggtgcggct gtcggcgatt ccttgtgcaa tgtgcttgca aaagcgggtt acgatgtgag
    12841 ccgcgaatac tacattaacg atgctggaaa ccagattaac aacctggcgc tttctgtaga
    12901 agtccgttac tttgaagcgc ttggactgga aaaaccgatg ccggaggacg gctaccgcgg
    12961 tgaggatatc atttcaatcg gaaagcgtct cgctgaggaa tacggcgacc gtttcgtcaa
    13021 cgaagaagaa agcgaacgcc tcgcattttt ccgtgagtac ggtttgaaat acgagctgga
    13081 gaagcttcgc gtagacttgg aaaacttccg cgtgccgttt gacgtgtggt attctgaaac
    13141 atcactgtac caaaacggaa aaatcgataa ggcgctggac gcgctgcgtg agaaaggcca
    13201 tgtctatgag gaagacggtg cgacttggtt ccgttccaca acgttcggag atgacaaaga
    13261 ccgagtactg atcaaaaagg acggcacata cacatacctg cttcctgata tcgcctacca
    13321 taaggacaag cttgaccgcg gctttgataa gctggtcaac gtatggggcg ccgaccacca
    13381 cggctacatc ccgcgtatga aagcggcaat cgaagcgctt ggctatgaaa aaggaacgtt
    13441 ggaagtagaa atcattcagc tcgtgcacct ttacaaaaac ggcgagaaaa tgaaaatgag
    13501 caaacggacg gggaaagcgg taacgatgcg cgacctgatt gacgaagttg gcctggatgc
    13561 cgtgcgttat ttcttcgcga tgcgcagcgc tgatacgcat atggattttg acttggatct
    13621 tgctgtatca acatctaacg aaaaccctgt gtattatgcg caatacgcac atgcccgcat
    13681 ttgcagcatg cttcgccaag gggaagagcg aggacttaag ccggcggcag accttgattt
    13741 cagccctatt caatcagaaa aagaatatga tctgctgaaa acaatcggcg gcttcccaga
    13801 ggcagtggcg gaagcggcgg aaaaacgaat tccgcaccgt gtgacgaatt atatttatga
    13861 cttggcttca gctctgcaca gcttctacaa tgcggagaaa gtcatcgacc ctgaaaacga
    13921 agagaaaagc cgcgcgcgct tagctttaat gaaagcaacg caaatcacgc tgaacaacgc
    13981 gcttcaattg atcggcgtat cggctcctga aaaaatgtaa ccaagctgaa aggacaaagc
    14041 cagagggctt tgtccttttt tgttaaaaaa tcgtgtgata tagttcacaa tcttcctcgc
    14101 cgagtttttg tatgataagg ctgattattg aatcagtgaa aggggcaagc cgaatgatta
    14161 accgtcaaca ctttcaatta tcgctgcagt cattaagctt ggtggcaggg tttatggttt
    14221 gggtgctgat ttcgtcactt atttcccaaa tcacattaga tattcatttg agcaaaggcg
    14281 aaatttcctt ggtaacggcc atacccgtta tattaggatc gcttctccgc attccgctgg
    14341 ggtatttgac caacaggttt ggcgcgcgga tcatttttat gatcagcttt atattgcttt
    14401 tattccctgt attttggatc agtattgcag attccctgtt tgatttaatc gcgggcggtt
    14461 ttttcttagg gattggggga gccgtttttt ccattggggt tacatctctt ccgaagtact
    14521 atcctaaaga aaaacatggc gttgtaaacg gtatttacgg tgccgggaat atcggaaccg
    14581 cgatcactac atttgcagct cccgtgattg ctcaagcggc ggggtggaaa agtacggtgc
    14641 aaatgtatat ggctctgttg gctttatttg ctttgctgca ctttttcttc ggtgaccggc
    14701 atgagaagaa agtgaaggtg tccgtaaaga ctcaaatcaa agccgtttac cgaaatcatg
    14761 tgctgtggtt tctgagtctc ttttatttta ttacgtttgg cgcctttgtc gcttttacaa
    14821 tctatctgcc aaactttctt gttgagcagt ttgatctgag tcctgcggat gccgggctgc
    14881 ggacggcagg ttttattgct gtatccacgc tgctcaggcc ggcgggcggg tggctggctg
    14941 ataaagtgag tccgctccgc atcctgatgt ttgtctttgc cggcctgaca ttatcgggcg
    15001 tcatcctgtc gttttcgccg acgatcggca tttatgcctt tggggcgtta acggttgcgg
    15061 tgtgctccgg gattggaaac gggacggttt ttaaactggt tcctttctat ttttctaagc
    15121 aggcgggaat cgccaacgga gttgtgtctg ccatgggcgg attaggcggc tttttccctc
    15181 cgctgatcct ggcgagtgta tttcaggcga cgggacaata cgccatcgga tttatggcgc
    15241 tttcggaagt cgcgttagca agctttgtca ttgtcatatg gatgtattgg caggaaagaa
    15301 tgaaaacaca cacagagaga agcgggcaca gcgtaaactg acgggccgcc ggcgattggg
    15361 gaattcacga gattgtaagt tttttctgaa aagcgcaaat gatttcacgt tacaatagat
    15421 acacaacgtg acttttcttc gaggtgagct catgaacttt ctctctgttc gaacatctga
    15481 taaggatctt atttccagtg atcttcatca attgctggaa tccatcagca caaaaagaaa
    15541 aatcgaaaaa cacacatacc tgtttcgaga aggaatggat gcagaagagc tttatctgat
    15601 tcagtcagga ctcattgaaa tcgggaagct tacggctgac ggcaaagacc tgacgcttag
    15661 aatctgccaa aaaaatgata ttgtcggtga attaacactt ttcacagaag aaccgagata
    15721 tatgctcagt gcaaaagtac tggaggatgg cgaagtgctc gtcatcaata agagcagact
    15781 tgaaaaggaa cttatccaca acggtgcttt gacatttgaa tttatgaaat ggatgagcac
    15841 ccatttgcgc aaaattcaat ccaaaatcag agaccttctt cttcatggca aaaaaggggc
    15901 gctctactcc accctcatcc gcttgtcaaa cagctatggg gtgaaccgga gtgacggtat
    15961 tctcattaac attgccctga caaaccagga tttggcaaaa ttttgcgcgg ctgcaagaga
    16021 gagcgtcaac cgcatgctgg gggatctccg caaacaaggg gttatttcaa tagaggattc
    16081 cggaaagatt gtactgcatc agcgggacta tttacggtgt gagattgagt gcgaaaattg
    16141 cccgttagag atttgtaata ttgattaaga ggaaacaagg acagcaatat gtccttgttt
    16201 ttatcttgtt agccaaatac acatgatggc gaaaaagaag cacgcattga cgatttcaag
    16261 tatgccgatc gtttgaacag gccacttctt tccgtgaaaa aaccatgcac gcaaactgct
    16321 ggggataaag gcgagaacgg cccatccacc tccgagagct gcggaaagta aggggaggat
    16381 caggtgatag ccccacgacc agtaagcaaa tactctatta ttcttctccc ggatcaccga
    16441 cttcacataa aatgaacttc cgataaaaaa caaagcagat tgtgcgaaaa taaaccatgc
    16501 ccagccgtca agagtctccg tccccagcca gcagctggcg agtccgcctg tacaaaagaa
    16561 taagacgccc gcaaaatcat tcagcagcgc tcgttcattt tttagccggg cataatacac
    16621 atgaatgaga aacagcggca gcaaagaaaa ggcaagccag ataaaagacg gcttatggat
    16681 gacagcggca agcaaaaagc tgcaggctgg aaaactgtaa gaaattatcc acttttgata
    16741 gggtttgatt tgtttctttt ttaatgccag cgtaacagga taaacagcca aataaagaaa
    16801 aagccagcct aaaaataggg gtatatgcca aagaaccgct cctcccttca ccataccgag
    16861 gcaaaacgga atcagcagca tggcccaagc gccgtgctgc ttcggaataa gcgccttcat
    16921 cgaaacactc ctttcttgtt tcattataaa agcaaaaata ccgccaataa gtgacattca
    16981 tcatatcatc tgtgaaatac atcactgctg tcatggatcg gccgggctac actaaagcta
    17041 tccttagcac aggaggcttc cctatgaatc agtgtgacta tttatttttt ttgaaacaac
    17101 ttcctatgtt taatgaagtg cctctatcca ttgtcgaaac attgctgaat aacgggacgt
    17161 ttatccgcgg ttcatgtgat caggatccat cttttctcca ttctcaatcc atttatattg
    17221 tattaaaagg cagtattcgt tttattgaca gcaggctgcc tgaagggtcg caaaccgtgg
    17281 cgctgtggga aaaaggcgat gtgtttccca ttgatcaaaa aggcgggatg ttcttatctc
    17341 cattcatttc agtccgaaca tccgaagaca ttcttatgct caatatccct ttttacatat
    17401 taaagaaaat catgtcctat tatccgcagc tgcagatgaa ttttctggtg atgctccagc
    17461 aaaatgtctt tttctcttat gagctgtttt tgcgatacat gcatagatct caggacgaaa
    17521 acgctgagcc cgattcctaa aaggaaccgg gttttttgtt cggtatttcc attccttctt
    17581 cctcatgtga actttctgtg aaaaaagggg agtgtgtgac atagttcaca aggaaacatc
    17641 ctgcctctgt atatagtgaa tttagaatac ctgactcgga aggagtgaaa tattcatgaa
    17701 aaaaaagaaa atgagtccgt tgtttaggag attaaactat ttctctccta ttgagcatca
    17761 atcaaataaa catagccaaa caacctatga agatcgtgat tgggagaatg tatacagaaa
    17821 cagatggcag tacgataagg tcgtccgctc tacccacggt gtcaactgca cagggtcctg
    17881 cagctggaat atatacgtga aaaacggcat cgtcacgtgg gagggtcaaa acttgaatta
    17941 tccgtcaacc ggcccggata tgcctgattt cgaaccgaga ggctgtccgc ggggggccag
    18001 tttttcatgg tatatttaca gcccgctccg tgtgaaatat ccgtacgtgc gcagtgtgct
    18061 gatcaatttg tggcgggaag cattgcaggc tcatcaaaac cctttggaag catggaaatc
    18121 gatcgttgaa aatccggata aagcgaagtc ctataaacag gcgcggggaa agggcggctt
    18181 tgtgcgcgct gaatggccgg aggtgctgaa gctgatttct gcttctttgc tgtatacggt
    18241 tataacatac ggccctgacc ggaatatcgg gttttctccg attccggcta tgtctatgat
    18301 cagccatgcg tcaggctcgc ggtttatgtc tttgattggc ggccctatgc tcagtttcta
    18361 tgattggtat gcggatcttc ccccggcatc cccgcaaatc tggggcgacc agacagacgt
    18421 cccggaaagc agtgattggt acaactcagg ctatatcatc acatggggct ccaatgtgcc
    18481 gttaacgagg acgccggatg cgcatttttt ggcagaagcc cgctataaag gcgctaaggt
    18541 catctcaatc agcccggatt tcgcggaatc ctctaaattt gcagatgact ggctgagcat
    18601 ccgccaagga acagacggcg cgcttgcgat ggcgatgggt catgtgatcc tgcaggagtt
    18661 ttacgttaat cagaagacag agcgtttcat agagtatgca aagcaatata cggatttccc
    18721 gttctttgtc actctaacta aagaggatgg cgtgtatacg gccgggcgtt ttcttcatgc
    18781 aaaggacatc gggcggcaga cggagcatga tcagtggaag cctgcggtgt ggaatgaacg
    18841 tacaagcgca ttcgcgatcc cgcaaggaac aataggctcc cgctgggacg gccaaaagaa
    18901 atggaacctg cacatgatag atgaagaaac aggcgaatcg attgaacccc ggctttcggt
    18961 gctcggcata gaggacgaaa tcggcacggt tcgaatccct tatttctcaa atgaggggaa
    19021 cagagtgctt gagcgagatc tgcctataaa aaaactggcg ctggacaatg aggatgtgta
    19081 tgtcacaacc gtatttgact tgattttggc taactacggc gtgaatcggg ggatcggggc
    19141 aaaatcagcc tgctcgtatg acgatcctga gccgtttacg ccagcctggc aggagcaggt
    19201 gacagggatc aaaaaagaga tggtcattaa cattgccagg gaatttgctc aaaatgcgat
    19261 cgatacagag ggccggtcca tgattatcgt aggagcgggg atcaaccact ggttcaactc
    19321 agacacgatc taccgggcgg tgttaaatct tgttttactg gtaggcgccc aaggcgtaaa
    19381 cggcggaggc tgggctcatt atgtgggaca ggaaaaactc cgtcctgctg aaggctggca
    19441 gacgatcgcc aacgctaagg attgggaggg ggcgccaaag ctgcaaaacg gcacttcctt
    19501 tttctatttt gcgactgacc agtggcgcta cgaggatcag ccggtcagtg acttagcatc
    19561 tccgatcgcg gcatcctccc gctacaagca tcacgccgac tacaatgtgc tggcggcaag
    19621 actcgggtgg cttccgtctt atccgacatt tgataaaaac ggaattgacc tgtacaaaga
    19681 agctgaaaaa gcgggagcga agacaacaaa agacgttgct gactatgtgg cccgccagct
    19741 tcaagagaaa aaactgaaat ttgccattga agatcctgac aatgaagcga attttccgag
    19801 aaacctgttc gtgtggaggg cgaatctgat ctccagttcg ggaaaagggc atgaatattt
    19861 tctcaagcat ctcttgggaa cgacgaacgg cttgatgaat gacgccagcg acagtatccg
    19921 tcctgaagaa atcaagtggc gcgagcaggc accggaagga aagctcgatt tgttaatcaa
    19981 tctcgatttc cgaatggccg gtaccgcctt gtattccgat atcgtgcttc cggcggcgac
    20041 atggtatgaa aaacacgatc tcagcagcac tgatatgcat ccgtttatcc acccctttgc
    20101 cccggctatt tcggctcctt gggaatcgaa gtcggactgg gatattttca aggctttatc
    20161 aaaagccgtc tccaatctcg cggaagaagt tgatatgaag ccggtaaaag aagctgtcgc
    20221 cgcaccgctc ctccatgaca cgatgcagga aatggcgcag cctctcggaa aaatcaagga
    20281 ctggagcaaa ggcgaatgcg aagccgtccc ggggaaaaca atgccgaaca ttcaagtcgt
    20341 tgaaagggac tacaaacaaa tctttcataa aatgaccgcg ctcggcccaa acgccgcctt
    20401 aaaaccaagc ggaacaaaag gcatgagctg gtcgattgcc gatgaatacg aatcactcaa
    20461 aaaaaggctg ggagaagtca ccacagacag tgtcgcaaag ggatgtccga atataagcga
    20521 ggccaagcag gcggcagaag ccgttttaac cctttcgtcc acgtcgaatg gaaaagttgc
    20581 cgtaaaagca tgggaatcgc ttgaagacat cacgaatctg aagctgaaag atctggctga
    20641 agagcgggag gaagaatgct ttacgttcga acaaatcacg gctcagccca aaacggtgat
    20701 cacatctccg gcatttacag gctcggaaaa aggcgggcgc aggtattcgc cgtttacgac
    20761 aaatgtggaa aaattaatcc cttggcgtac gctgacaggc agacaatcct attatgtcga
    20821 tcatgagctg atgatggagt tcggggaaac gatggcgacc tttaaaccga tcctccagca
    20881 tcgccctttc ttaagcaaac ggccagatca agagggcaaa gaaatcgttc tcaattattt
    20941 aacgccgcat aataaatggt ccgtgcacag catgtatttt gattccctgc cgatgcttac
    21001 gctattccgc ggcgggccga cagtatggat gaataaagat gatgcggcag atacggatat
    21061 caaagacaac gattggattg aatgctttaa ccgaaatggt gttgtcgtag ccagagcggt
    21121 tctgtctcac cggataccaa aaggaatggc gtttatgcac catgcccaag accgccacat
    21181 caacgtgccc ggcacaaaac tgaccaataa ccgcggaggc acccataaca gtccgacaag
    21241 gattcacgtt aagccgacac agatgatcgg cggctatgcc cagctcagct acggctttaa
    21301 ctactatggc cctacgggga atcagcgcga tctgaatgtg gtcatccgca agctgaagga
    21361 ggtcgattgg cttgaagatt aaagcgcaaa tcggaatggt catgaactta gataaatgca
    21421 tcggctgcca cacgtgcagc gtgacctgca aaaacacatg gacaaaccgt tccggtgccg
    21481 aatatatgta tttcaataat gtagaaacaa agccaggtat cggctatccg aagcaatggg
    21541 aggatcagga caaatataaa ggcggctgga ccttaaaaaa aggaaagctc gagctgaaat
    21601 caggcccgaa aac
//
