LOCUS       NZ_JAHTIK010000001     11023 bp    DNA     linear   CON 01-NOV-2023
DEFINITION  Kitasatospora sp. DSM 101779 AL-KSAMP_AS10_SC01, whole genome
            shotgun sequence.
ACCESSION   NZ_JAHTIK010000001
VERSION     NZ_JAHTIK010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kitasatospora sp. DSM 101779
  ORGANISM  Kitasatospora sp. DSM 101779
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 8354403)
  AUTHORS   Samborskyy,M., Nasim,S., Bilyk,O. and Luzhetskyy,A.
  TITLE     Kitasatospora nimphea DSM101779 genome sequencing and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8354403)
  AUTHORS   Samborskyy,M., Nasim,S., Bilyk,O. and Luzhetskyy,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUL-2021) DNA Sequencing Facility, Explogen LLC, 20
            Zelena Street, Lviv 79004, Ukraine
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 24-JAN-2021
            Assembly Method                   :: Newbler v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/01/2023 05:30:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,790
            CDSs (total)                      :: 7,686
            Genes (coding)                    :: 7,384
            CDSs (with protein)               :: 7,384
            Genes (RNA)                       :: 104
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 302
            CDSs (without protein)            :: 302
            Pseudo Genes (ambiguous residues) :: 0 of 302
            Pseudo Genes (frameshifted)       :: 70 of 302
            Pseudo Genes (incomplete)         :: 265 of 302
            Pseudo Genes (internal stop)      :: 17 of 302
            Pseudo Genes (multiple problems)  :: 46 of 302
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:18:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4275868
            Orig. end                         :: 4286891
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHTIK010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..11023
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="butyrolactone"
                     /region_number="16"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..11023
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11023
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:6023](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6023
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     misc_feature    complement(371..384)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.82"
                     /tool="antismash"
     gene            549..2180
                     /locus_tag="KSNIM_RS19420"
                     /old_locus_tag="KSNIM_19230"
     CDS             549..2180
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (8-423). E-value: 1.6e-49.
                     Score: 160.5. Matches aSDomain:
                     nrpspksdomains_KSNIM_RS19420_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035377.1"
                     /locus_tag="KSNIM_RS19420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSNIM_19230"
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="WP_263104468.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-40, bitscore:
                     137.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKLQDALRHAAERPDHVALVDGGRRITWSELADEIAKVAGGLAA
                     VLPGGRPARAAFLCCNGWELVVTMAAFETLGVSITGLDFEATPEATAEALEQLRPTVVV
                     SSKLHRPLLIASGWADREGVLQVHLHGVGEELAAPEPIVPDPQAGEPVHYSTLAAAQTA
                     VTAPISQPYEHFAVSYDAAGSPRLVIRRRSFEARRLAELVDEFAFDEDDTYLVTVPMYH
                     ASGPGWARVFFALGGTVVLGPYHDLAEMCRLITDEGVTTTLMVPPVLSRLLAHPASAEL
                     RRTSRLRFLLTGGQHLNRWIVNEAWDRFGPVLHHYYGSTETGLVTLLGPDELALSPCRS
                     GRAMPGIGIAVLDAEHRPLPPGVRGRVAVASYQLMDAYGDAPAPSVLVDLSDGQGPRPF
                     LLTGDDGVIDYEGRLELTGRTSGAVRARADGDRDSAFFGLETELLDQPAVRDLAVLRVT
                     VPDHGPVLAVPFVPVARDLEASAYRAVSAVCARRVPWISAHVIAVDAIPYSPTGTIRTG
                     ELLTEIMPLVNLYIHLDKQSATEIPA"
     aSDomain        573..1817
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KSNIM_RS19420_AMP-binding.1"
                     /evalue="1.60E-49"
                     /label="KSNIM_RS19420_AMP-binding.1"
                     /locus_tag="KSNIM_RS19420"
                     /protein_end="423"
                     /protein_start="8"
                     /score="160.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RHAAERPDHVALVDGGRRITWSELADEIAKVAGGLAAVLPGGRPA
                     RAAFLCCNGWELVVTMAAFETLGVSITGLDFEATPEATAEALEQLRPTVVVSSKLHRPL
                     LIASGWADREGVLQVHLHGVGEELAAPEPIVPDPQAGEPVHYSTLAAAQTAVTAPISQP
                     YEHFAVSYDAAGSPRLVIRRRSFEARRLAELVDEFAFDEDDTYLVTVPMYHASGPGWAR
                     VFFALGGTVVLGPYHDLAEMCRLITDEGVTTTLMVPPVLSRLLAHPASAELRRTSRLRF
                     LLTGGQHLNRWIVNEAWDRFGPVLHHYYGSTETGLVTLLGPDELALSPCRSGRAMPGIG
                     IAVLDAEHRPLPPGVRGRVAVASYQLMDAYGDAPAPSVLVDLSDGQGPRPFLLTGDDGV
                     IDYEGRLELTGRTSGA"
     gene            2177..2557
                     /locus_tag="KSNIM_RS19425"
                     /old_locus_tag="KSNIM_19235"
     CDS             2177..2557
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSNIM_RS19425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KSNIM_19235"
                     /product="hypothetical protein"
                     /protein_id="WP_263104469.1"
                     /transl_table=11
                     /translation="MTTPVPPHTSDDELDEADLGTRLLSLERALTELPAARQTALLIGE
                     LPDYGDVLLVAFVPADAEREESTQRAARAACARLVPALPALVIPVDDIPYTLDGELRGQ
                     QLFDEMLPQIARDLLLPKEMSA"
     gene            complement(2659..3825)
                     /locus_tag="KSNIM_RS19430"
                     /old_locus_tag="KSNIM_19240"
     CDS             complement(2659..3825)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035385.1"
                     /locus_tag="KSNIM_RS19430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSNIM_19240"
                     /product="oxidoreductase"
                     /protein_id="WP_263104470.1"
                     /transl_table=11
                     /translation="MSILDDPCTTARPAGLPGSLTSAADALRPTALGQAAEADRQRGID
                     AALADRLAGSGFARHFVPRRWGGAEGTFAELVAATVSLAEGCTSTAWCAALQAAHGRLA
                     AFLPEAGQQEIWGSSPDVPIAAALVPPTGRLERTADGGALVTGRWRCVSGVRNAAWVLL
                     ALPDPAALPGDFLIVAVPRGAVTVHDTWHSNGLRATGSHDVSVAEPLAVPAHRCLAFMD
                     LVRASAAPGRARCHGVPPRLVAGLAFAAPAVGAARGALKAWAAPLADSHGPGGPAVSPA
                     RCEVLARASAEIDIAASLLADAALRADAGAAGDRAVGRNLRDTALAVELTVSAVERLFR
                     AGGVAAQWQDSALQRAWRDVHTLAAHGALSWDAAAAEYTRTGLAAHAG"
     misc_feature    complement(3814..3829)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.51"
                     /tool="antismash"
     misc_feature    3817..3832
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.58"
                     /tool="antismash"
     misc_feature    complement(3959..3973)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.37"
                     /tool="antismash"
     misc_feature    3981..3990
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(4058..4072)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.93"
                     /tool="antismash"
     misc_feature    complement(4064..4078)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.2"
                     /tool="antismash"
     misc_feature    complement(4064..4079)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.6"
                     /tool="antismash"
     misc_feature    4065..4078
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.08"
                     /tool="antismash"
     gene            4140..4790
                     /locus_tag="KSNIM_RS19435"
                     /old_locus_tag="KSNIM_19245"
     CDS             4140..4790
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF041196.1"
                     /locus_tag="KSNIM_RS19435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSNIM_19245"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_263104471.1"
                     /transl_table=11
                     /translation="MAASGNPVSGTSRSRGTAAGRSAPALKQARALRTRATVLEAAAAL
                     FARKGFKVVTMQEIAEEAGATKGAVYFHFPNKEALAAELVGNFYAAAPKTTSALADPDL
                     KPLETVRRLTMETARRLRDDAVAQAAVRLQTERLVIDADLPLPFIDYIAVYTLLLERAK
                     EAGELPADVSADSLARTIVASFFGVQHVSWILHDRADVVARVEELLDLILPPG"
     misc_feature    complement(4911..4931)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.22"
                     /tool="antismash"
     gene            5001..6023
                     /locus_tag="KSNIM_RS19440"
                     /old_locus_tag="KSNIM_19250"
     CDS             5001..6023
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041195.1"
                     /locus_tag="KSNIM_RS19440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSNIM_19250"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_263104472.1"
                     /sec_met_domain="AfsA (E-value: 2.8e-19, bitscore: 67.7,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTFAPDQLTHPTAGLLPRQRSAADLDFHRTVSRKLVHKAAVSEV
                     FLTDSARAAADSYLLAAQWPRDHAVFQPGPGGTADSMVIIETVRQATMFTFHEYYGVPL
                     ELPFVAKSFDFEMTDGQAARASFGAPQEVTLDLVVDMPADRRAGRRMPFRTHTVVHAGA
                     GRPCARVTIGGEILDPALYRRLRAARPAAPELPAGDGGPVAATPAQVGRRRPDDVVLLA
                     AQPGDDARWRLRVDQGHPTFFDHGSDHVQAVLLLEALRQSGLLADGPAGGALAEVLTGL
                     RVEFHAYGEFGTPILLDARVTGSEPGARTVRATAAQAGRPIAQADLVFRPAALPGGPTS
                     "
     gene            6084..>6377
                     /locus_tag="KSNIM_RS19445"
                     /old_locus_tag="KSNIM_19255"
     CDS             6084..>6377
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019888568.1"
                     /locus_tag="KSNIM_RS19445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSNIM_19255"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_263104473.1"
                     /transl_table=11
                     /translation="MELQHLRSFLEVSSEMSFTRAAKKLNYAQSSVTAQIQHLEASLGA
                     VLFDRRGRRIALTESGLRLRPVAERIVALADLAHREVAGTADRQPGRPAGRPA"
     assembly_gap    6378..6389
                     /estimated_length=12
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(6396..7061)
                     /locus_tag="KSNIM_RS19450"
                     /old_locus_tag="KSNIM_19260"
     CDS             complement(6396..7061)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024242.3"
                     /locus_tag="KSNIM_RS19450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSNIM_19260"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_263104474.1"
                     /transl_table=11
                     /translation="MNEVSLGRVRIAVVEGAAPDGAGDDLRVSQHRTRAGEAYLRVSCP
                     LSDPLAVPELLRQLADQGALPSDRTAELLARGITGLVAQACADYMDRDQDSPRPARSSG
                     LARRAMLQRIKHFARSRLADPELKPEMLAQHHHISLRYLQKLFQEHGQSPASWIRDERL
                     HRCCAELRDPRLAHLTIAMIGERSGLYGASHFSRLFRDRYGISPREYRRDHARLTDAA"
     misc_feature    7230..7243
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.35"
                     /tool="antismash"
     misc_feature    complement(7262..7276)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            7459..8466
                     /gene="gap"
                     /locus_tag="KSNIM_RS19455"
                     /old_locus_tag="KSNIM_19265"
     CDS             7459..8466
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0019682 - glyceraldehyde-3-phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="gap"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011559801.1"
                     /locus_tag="KSNIM_RS19455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSNIM_19265"
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="WP_263104475.1"
                     /transl_table=11
                     /translation="MAIKVGINGFGRIGRSFFRAALEQNADIEIVAVNDLTDAATLAHL
                     LKYDTTLGKLPVPVTAGQGEIVVDGRSIRVTAERNPADLPWAELGVDVVVESTGVFTDA
                     EKAKAHLAAGARKVIISAPATNQDLTIAIGINDAVYDEDVHSVVSNASCTTNCLAPLAK
                     VLNDGLGIEQGLMTTVHAYTQDQNLQDGPHKDLRRARAAAGNIVPTSTGAAKAIGQVLP
                     ELNGKLDGYALRVPVVVGSVTDLTVTVARDTTVEEVNALFAKAAEGALAGVLRYTDEPL
                     VSNDIVTDPASCIFDSGLTKVINNRTVKVAGWYDNEWGFSNRVVDTVLLIGKHA"
     gene            8605..9504
                     /locus_tag="KSNIM_RS19460"
                     /old_locus_tag="KSNIM_19270"
     CDS             8605..9504
                     /EC_number="1.-.-.-"
                     /EC_number="1.4.3.5"
                     /GO_function="GO:0004733 - pyridoxamine phosphate oxidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013412.3"
                     /locus_tag="KSNIM_RS19460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSNIM_19270"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_263104476.1"
                     /transl_table=11
                     /translation="MVKTPYHEGEQAVQQRAGEGHPGWGSPMFEAAIPPPFDMFLRRQR
                     MLVVGGVDDDGAAWSTVLTGPRGFAGAVGSHTVHVKALPVPGDPLEHVFDEQRDIGMLA
                     IEPQTSQRIRINGVARRDGDLLVVTTEQVLGNCPKYLQQRVLRPDAPQAAAPTVRRSTV
                     LDADQQRWITGADTFFIASRAPQHGADASHRGGAPGFVEVPAPDRIVWPDYFGNSFYMT
                     LGNLQLDPACGLTFLDWEAGHALHVTGKARIDWDESRTKAVQGALRLVEFDVEQVVEVR
                     DFTTLRWKFAAPSPFNPT"
     gene            9533..10606
                     /gene="hisC"
                     /locus_tag="KSNIM_RS19465"
                     /old_locus_tag="KSNIM_19275"
     CDS             9533..10606
                     /EC_number="2.6.1.9"
                     /GO_function="GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (31-349). E-value:
                     2.9e-54. Score: 176.5. Matches aSDomain:
                     nrpspksdomains_KSNIM_RS19465_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="hisC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005315098.1"
                     /locus_tag="KSNIM_RS19465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSNIM_19275"
                     /product="histidinol-phosphate transaminase"
                     /protein_id="WP_263104477.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.8e-52, bitscore:
                     176.4, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 3.3e-05, bitscore:
                     21.8, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRYDAPRLRAAMAAVPDYVPGRSPRQGCENLKLSSNENPYPPLP
                     SVVAAVREQAGRINRYPDPACTALAEALAARLDVPADRLVFGTGSVAVGRLLVRATAGP
                     GDEVLYAWRSFEAYPIMAEVCGATSVRVPLLADERHDLDAMADAVTDRTRLIFLCTPNN
                     PTGTVVRHAEVERFLDRVPSDVTVVLDEAYTEFVRDPDAADGLDLQRRHGNVVLLRTFS
                     KAYGLAGLRIGYAVAHPELAAVLRKVGLPFGVSGLAQDAALASLAAEDELLDRVELLVK
                     ERARVTAALRESGFVLPDSEANFVWLRLGGRTAEFTEACAALGAVVRPYGTDGVRVTVG
                     EPEANDVVLRVAAAWRH"
     aSDomain        9626..10579
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KSNIM_RS19465_Aminotran_1_2.1"
                     /evalue="2.90E-54"
                     /label="KSNIM_RS19465_Aminotran_1_2.1"
                     /locus_tag="KSNIM_RS19465"
                     /protein_end="349"
                     /protein_start="31"
                     /score="176.5"
                     /tool="antismash"
                     /translation="LKLSSNENPYPPLPSVVAAVREQAGRINRYPDPACTALAEALAAR
                     LDVPADRLVFGTGSVAVGRLLVRATAGPGDEVLYAWRSFEAYPIMAEVCGATSVRVPLL
                     ADERHDLDAMADAVTDRTRLIFLCTPNNPTGTVVRHAEVERFLDRVPSDVTVVLDEAYT
                     EFVRDPDAADGLDLQRRHGNVVLLRTFSKAYGLAGLRIGYAVAHPELAAVLRKVGLPFG
                     VSGLAQDAALASLAAEDELLDRVELLVKERARVTAALRESGFVLPDSEANFVWLRLGGR
                     TAEFTEACAALGAVVRPYGTDGVRVTVGEPEANDVVL"
ORIGIN
        1 cgggggcagc gcggtgtagc tggtggaggc cgccgcggca gcggtgccgt cgtcggcgga
       61 ggcctggccg gcgacgaggg tggcgccacc ggcggtgatg gcgagggcgg cggcgagggc
      121 gacgaaacgg cgcttcatgg ggctgttcct tccacggtgg gacgggcttg cggggcgtgg
      181 tgggacggtg cccggccgaa gctaccgacc ggccggacgg gggtgttgcc ggtccgcgca
      241 ccgggcgtcg tggatccgcg cacgtcgggc atatgtgcag gtggtggcgg tggcggcggg
      301 gtaggaaggg gtgcggaggg ggcgccggcg ggccgggcat cggatctgcc gattgctatt
      361 gataccttcg ggaaggtttg tttctatcgg gtgggtgtcc cgacgcgtgc ccgcgcattc
      421 ggcggcgacc gcgtgcagcg aagaagagcc cgaccttccc cagcgagacc gccgggcagg
      481 tgttccggcg ccccaaccga tggatgaacc agaagggcca actccagccc actggaacgg
      541 agttcgagat gatcaagctg caagacgccc tgcggcacgc cgctgaacgc ccggaccacg
      601 tcgcgctggt ggacggcgga cgccggatca cctggagcga actggccgac gagatagcca
      661 aggtggccgg cggcctcgcc gcggtgctgc ccgggggacg gccggcccgc gccgccttcc
      721 tctgctgcaa cggctgggag ctggtcgtca ccatggccgc cttcgagacg ctgggcgtgt
      781 cgatcaccgg cctcgacttc gaggccaccc cggaggcgac cgcggaggcc ctggaacagc
      841 tgcgcccgac cgtcgtggtc agcagcaagc tgcaccgacc gctgctcatc gcgtcgggct
      901 gggccgaccg cgagggcgtg ctgcaggtcc acctgcacgg cgtgggcgag gagttggccg
      961 cgcccgagcc gatcgtcccg gacccgcagg ccggcgagcc ggtccactac tcgacgctgg
     1021 ccgccgcgca gaccgccgtg accgcgccga tctcccaacc ctacgagcac ttcgcggtca
     1081 gctacgacgc cgcagggagc ccccggctgg tgatccgccg ccgctccttc gaggcccgcc
     1141 ggctcgccga gctggtcgac gagttcgcct tcgacgagga cgacacctac ctggtcaccg
     1201 tcccgatgta ccacgcctcc ggcccgggct gggcgcgggt gttcttcgcc ctgggcggca
     1261 ccgtggtgct cggcccgtac cacgacctcg ccgagatgtg ccggctgatc accgacgagg
     1321 gcgtcacgac caccctgatg gtgccgccgg tgctctcccg gctgctcgcc cacccggcct
     1381 ccgccgagct gcggcggacc tcccggctgc gcttcctgct caccggcggc cagcacctca
     1441 accggtggat cgtcaacgag gcctgggacc gcttcggtcc cgtcctgcac cactactacg
     1501 gctccaccga gaccgggctg gtcaccctgc tcggcccgga cgagctggcg ctctcgccct
     1561 gccgctccgg ccgcgccatg ccgggcatcg ggatcgccgt gctggacgcc gagcaccgcc
     1621 cgctgccgcc cggcgtgcgc ggccgggtcg ccgtcgcgag ctaccagctc atggacgcct
     1681 acggggacgc ccccgcgccc tccgtgctgg tcgacctgag cgacggccag ggcccgcgcc
     1741 cgttcctgct caccggagac gacggcgtca tcgactacga gggccggctg gaactcaccg
     1801 gccgcaccag cggcgccgta cgggcccggg ccgacggcga ccgcgactcg gccttcttcg
     1861 ggctggagac cgaactgctc gaccagccgg ccgtccgcga cctggccgtg ctgcgggtca
     1921 ccgtgccgga ccacggcccc gtcctcgcgg tgcccttcgt cccggtggcc cgggacctgg
     1981 aggcgtccgc ctaccgcgcg gtcagcgcgg tctgcgcccg ccgggtgccg tggatctcgg
     2041 cgcacgtgat cgcggtcgac gccatcccgt acagccccac cggcaccatc cgcaccggcg
     2101 agctgctcac cgagatcatg ccgctggtca acctctacat ccacctggac aagcagtcag
     2161 ctacggagat ccccgcatga ccacgccggt tccgccgcac acctccgacg acgagctgga
     2221 cgaggccgac ctcggcaccc ggctgctctc cctggaacgg gcgctcaccg agctgcccgc
     2281 ggcccgccag accgcccttc tgatcggtga actcccggac tacggcgacg tgctgctggt
     2341 cgccttcgtg ccggccgacg ccgaacgcga ggagtccacc caacgggcgg cccgggccgc
     2401 ctgcgcccgg ctcgtcccgg cgctgcccgc gctggtgatc ccggtcgacg acatcccgta
     2461 caccctggac ggcgagctgc gcggacagca gctcttcgac gagatgctgc cgcagatcgc
     2521 ccgcgacctg ctgctgccca aggagatgtc ggcctgagcc ggactccccg gtgccggtcg
     2581 cgcccgggca ccggggcccg cggcccgggg gccggcgggg gcacgaaacc ccgccggcgc
     2641 ccgggccgca cccgtgcctc agccggcgtg ggcggccagt cccgtccggg tgtactcggc
     2701 ggccgccgcg tcccagctga gcgccccgtg cgcggccagc gtgtggacgt cccgccaggc
     2761 ccgctggagc gccgagtcct gccactgggc ggccaccccg ccggcgcgga acagccgctc
     2821 caccgcggag acggtgagtt ccaccgccag tgcggtgtcc cgcaggttgc ggcccaccgc
     2881 gcggtcgccg gccgccccgg cgtccgcccg cagtgcggcg tccgccagca gcgaggccgc
     2941 gatgtcgatc tcggcggagg cccgtgccag cacctcgcag cgggccgggc tgacggccgg
     3001 accgcccggc ccgtggctgt ccgccagcgg tgccgcccac gccttcagcg caccgcgcgc
     3061 cgcccccacg gcgggcgcgg cgaaggcgag tccggccacc agccgcggcg ggacaccgtg
     3121 gcagcgggcc cggcccggtg ccgcggaggc ccggacgagg tccatgaagg ccaggcagcg
     3181 gtgcgccggg acggccagcg gttcggccac actgacgtcg tggctgccgg tggcgcgcag
     3241 cccgttgctg tgccaggtgt cgtggaccgt caccgccccg cgggggacgg cgacgatcag
     3301 gaagtcgccc ggcagggccg ccgggtcggg cagtgcgagc agcacccacg ccgcgttccg
     3361 cactccgctg acgcaccgcc agcggccggt gaccagtgcc ccgccgtcgg cggtccgctc
     3421 cagccggccg gtcggcggca cgagtgcggc cgcgatcggg acgtccgggg aggatcccca
     3481 gatctcctgc tgtccggcct cgggcaggaa ggcggccagc cgtccgtgcg ccgcctgcag
     3541 ggctgcgcac caggcggtcg aggtgcagcc ctccgccaac gagacggtcg ccgcgaccag
     3601 ttcggcgaac gtgccttcgg cgcctcccca gcgccgcggg acgaagtggc gggcgaagcc
     3661 ggagccggcc agccggtcgg cgagcgcggc gtcgatgccg cgctgccggt cggcctcggc
     3721 ggcctggccg agggcggtcg ggcggagcgc gtccgctgcc gacgtgagtg acccgggcag
     3781 cccggcgggc cgggccgtgg tgcagggatc gtccagaatg ctcatcgttg tctccccctg
     3841 tcgtggactg gcgtcacgtg ccgggacgac gccggccacc ggccgggggc cggggcaccc
     3901 gggcgccgtt cggttagggg cgcagcgggc ggggacgtcg tcgtcgacga ggacagcgtg
     3961 gccgaccgga accggtcgcg gaaggcggcc gcagcctcgg gtgcggatgc gggcgttccg
     4021 gggcgcgggt acgtggccgg ctgccgtcgt accgcagaat atttggaaca taccttcgtg
     4081 acgttatgat tcgcgcgaaa ctccggcaca accgtgccgg cacccctgga ggttgagcca
     4141 tggcggccag cgggaatccg gtcagcggca ccagcaggag ccggggaacg gcagcaggtc
     4201 ggagtgctcc ggccctgaaa caggcgcggg cactgcgcac ccgggcgacg gtcctggagg
     4261 ccgccgccgc actcttcgcc cgcaagggct tcaaagtcgt caccatgcag gagatcgccg
     4321 aggaggccgg tgccaccaag ggcgccgtgt acttccactt ccccaacaag gaggcgctcg
     4381 cagccgaact ggtcggcaac ttctacgcgg ccgcgccgaa gaccacctcg gcgctggccg
     4441 atccggacct caagccgctg gagaccgtcc gccggctgac catggagacg gcgcgccggc
     4501 tccgcgacga cgcggtggca caggcggccg tccggctgca gaccgagcgc ttggtgatcg
     4561 acgcggacct gccgctgccc ttcatcgact acatcgccgt ctacaccctg ctgctcgaac
     4621 gggccaagga ggcgggcgag ctcccggcgg acgtctcggc ggactcgctg gcgcggacga
     4681 tcgtggcgtc gttcttcggc gtccagcacg tgtcgtggat cctgcacgac cgcgccgacg
     4741 tggtcgcccg ggtcgaggag ctgctggacc tgatcctgcc gccgggctga ccgctccgcg
     4801 caccacgatc acggcggggg catcggctcc gcgcagttct gcgcggagcc gatgcccccg
     4861 cttttccctt gtggtgaaag ggacttgggg agggtcaaag cttggcaaca taccttcccg
     4921 gaggtatatt ttatttcggt cccagcgtcg gaccctggcc agtgccctgt cgttcacagc
     4981 cccgtggggg aaggctcgcg atggacacct ttgcaccaga tcagctgacc catccgacgg
     5041 ccggactgct gccgcggcag cggagcgccg cagatctcga cttccatcga acggtgtcgc
     5101 gcaaactggt ccacaaggcc gccgtctccg aggtgttcct caccgattcg gccagagccg
     5161 ctgcggacag ctacctgctg gccgcccagt ggccccgcga ccacgcggtc ttccagcccg
     5221 gaccgggcgg taccgcggac agcatggtca tcatcgagac ggtccgccag gccaccatgt
     5281 tcacgttcca cgagtactac ggagttccgc tcgaactccc tttcgttgcc aagagtttcg
     5341 acttcgagat gacggacggc caggccgccc gcgcctcctt cggggcgccg caggaggtca
     5401 ccctcgacct ggtcgtcgac atgcccgccg accgccgggc cggccggcgg atgccgttcc
     5461 ggacgcacac cgtcgtccac gccggcgccg gccgcccctg tgcccgggtg accatcggcg
     5521 gcgagatcct cgacccggcg ctctaccggc ggctgcgggc cgcccgcccg gccgccccgg
     5581 agctcccggc cggggacggc ggcccggtcg cggccacccc cgcccaggtg ggccggcggc
     5641 gccccgacga cgtggtgctg ctggccgcgc agccgggcga cgacgcccgc tggcggctgc
     5701 gggtggacca gggccacccc accttcttcg accacggatc cgaccacgtc caggcggtgc
     5761 tgctgctgga ggccctgcgc cagagcggcc tgctcgcgga cggcccggcc ggcggcgccc
     5821 tcgccgaggt gctcaccggc ctgcgggtcg agttccacgc gtacggcgag ttcggcacgc
     5881 cgatcctcct cgacgcccgg gtcacgggca gcgagcccgg cgcccgaacc gtacgcgcca
     5941 cggcggccca ggcgggccgt ccgatcgccc aggcggacct cgtgttccgc ccggccgccc
     6001 tgcccggcgg ccccacgtcc tgacggaccg tcgggtacgt ccgtgcaccg ccgtgcccgc
     6061 cggcccgctc cgaaggagtc ctgatggaac ttcagcatct gcgttcgttc ctcgaggtgt
     6121 cgagcgagat gagcttcacc cgggccgcca agaagttgaa ctacgcgcag tccagcgtga
     6181 ccgcgcagat ccagcacctt gaggcctcgc tcggcgccgt gctgttcgat cggcgcggcc
     6241 ggcggatcgc actcaccgag agcggcctgc ggctgcgccc ggtggcggag cgcatcgtcg
     6301 ccctggccga cctcgcccac cgcgaggtgg cggggacggc cgaccggcag cccggccgtc
     6361 ccgccgggcg cccggccnnn nnnnnnnnnc gtcggtcagg cggcgtcggt caggcgtgcg
     6421 tggtcgcggc ggtactcgcg cggcgagatg ccgtagcggt cgcggaacag ccggctgaag
     6481 tgcgaggcgc cgtacaggcc ggagcgctcg ccgatcatcg cgatggtcag gtgcgcgagc
     6541 cgcgggtcgc gcagctcggc gcagcagcgg tgcagccgct cgtcgcggat ccagctggcc
     6601 gggctctgac cgtgctcctg gaacagcttc tgcaggtagc gcagcgagat gtggtggtgc
     6661 tgcgcgagca tctccggctt cagctcgggg tcggcgagcc ggctgcgcgc gaagtgcttg
     6721 atccgctgca gcatggctcg gcgggcgagg ccggagctgc gagccggtcg gggcgagtcc
     6781 tggtcgcggt ccatgtagtc ggcgcaggcc tgggcgacca gcccggtgat gccgcgggcc
     6841 agcagttcgg cggtgcggtc ggagggcagc gcgccctggt cggcgagctg gcgcagcagc
     6901 tcggggacgg ccagcgggtc ggacagcggg cagctcaccc gcaggtaggc ctcgccggcg
     6961 cgggtgcggt gctgggagac ccggaggtcg tcgccggcac cgtccggggc ggcgccctcg
     7021 acgacggcga tccggaccct gccgaggctg acctcgttca cgttctccac caccggctgc
     7081 gcgggcggtt ccgctgcccg acgtggcgcc gttccgtgct cggtgtgccc gttctcggta
     7141 ggcaatgcat ccatggctcc cccgcgagga cttgaggccg cgttagccga cacccggtcc
     7201 gctccgggag ggcggacccc tccatcatgg aaacatacct tctggaaggt atgcggtttt
     7261 catcggcagc agtgatgccc ggcccgctgt gaagcgctcc ggccggatcg tgcgcggcgg
     7321 cacaacaacc cgtgcgcgtt ccgacaagtc gcccggccgg gccccgccta gcgtcggcgg
     7381 tacagatcag tgccgggcgc gcggatcacc ggcgctgcgc gcgcccccct gtgcacccac
     7441 ccagaagggg ccccacccgt ggcaatcaag gtaggcatca acggattcgg ccggatcggc
     7501 cggagcttct tccgcgccgc acttgagcag aacgccgaca tcgagatcgt ggcggtcaac
     7561 gacctcaccg acgcggcgac cctggcccac ctcctgaagt acgacaccac gctcggcaag
     7621 ctgccggtgc cggtgacggc cggccagggc gagatcgtcg tcgacggccg cagcatccgg
     7681 gtcaccgccg agcgcaaccc ggccgacctg ccctgggcgg agctgggcgt cgacgtggtc
     7741 gtggagtcca ccggcgtctt caccgacgcc gagaaggcca aggcgcacct cgcggcgggc
     7801 gcccgcaagg tgatcatctc ggccccggcc accaaccagg acctcaccat cgcgatcggc
     7861 atcaacgacg cggtgtacga cgaggacgtc cacagcgtcg tctccaacgc ctcgtgcacc
     7921 accaactgcc tcgccccgct ggcgaaggtc ctcaacgacg gcctgggcat cgagcagggc
     7981 ctgatgacca ccgtgcacgc ctacacccag gaccagaacc tgcaggacgg cccgcacaag
     8041 gacctccgcc gggcccgcgc cgcggccggc aacatcgtgc cgaccagcac cggcgccgcc
     8101 aaggccatcg gccaggtgct gcccgagctc aacggcaagc tcgacggcta cgcgctgcgc
     8161 gtgccggtcg tcgtcgggtc ggtcaccgac ctgaccgtca ccgtcgcccg cgacaccacc
     8221 gtcgaggagg tcaacgcgct gttcgcgaag gccgccgagg gcgctctggc cggcgtcctg
     8281 cgctacaccg acgagccgct ggtctccaac gacatcgtca ccgacccggc gtcctgcatc
     8341 ttcgactccg gtctcaccaa ggtcatcaac aaccgcaccg tcaaggtcgc cggctggtac
     8401 gacaacgagt ggggcttctc caaccgcgtc gtcgacaccg tcctgctgat cggcaagcac
     8461 gcctgaccgg cgccgccgac cgcacacgcg ggccgggcgc ccggggcgaa ccccgggtgc
     8521 ccggcccgcg cccgtgaacc caccgggcga ccggcggcga aacgcgccgc accggacgaa
     8581 cacccgcaca gagagggccg acccatggtc aagacgccgt accacgaggg cgagcaggcg
     8641 gtgcagcagc gggccggcga gggccacccc ggctggggct cgccgatgtt cgaggccgcg
     8701 atcccgccgc cgttcgacat gttcctgcgc cgccagcgga tgctggtcgt cggcggcgtg
     8761 gacgacgacg gcgccgcctg gtccaccgtc ctgaccggcc cgcgtggctt cgccggcgcc
     8821 gtcggctccc acaccgtcca cgtcaaggcc ctgccagtgc ccggcgaccc gctggagcac
     8881 gtcttcgacg agcagcgcga catcggcatg ctcgccatcg aaccgcagac cagccagcgg
     8941 atccggatca acggcgtcgc ccggcgcgac ggcgacctgc tcgtcgtcac caccgaacag
     9001 gtcctcggca actgccccaa gtacctgcag cagcgggtgc tgcgccccga cgcaccgcag
     9061 gccgccgcgc cgaccgtgcg ccgctccacc gtgctcgacg ccgaccagca gcgctggatc
     9121 accggcgccg acaccttctt catcgccagc cgggccccgc agcacggcgc cgacgcctcg
     9181 caccgcggcg gcgcacccgg cttcgtcgag gtccccgcgc cggacaggat cgtctggccg
     9241 gactacttcg gcaactcctt ctacatgacc ctcggcaacc tccagctcga ccccgcctgc
     9301 ggcctcacct tcctcgactg ggaggccggc cacgccctgc acgtcaccgg caaggcccgg
     9361 atcgactggg acgagtcccg caccaaggcc gtccagggcg ccctgcggct ggtcgagttc
     9421 gacgtcgagc aggtggtcga ggtccgcgac ttcaccaccc tgcgctggaa gttcgccgcc
     9481 ccctcgccct tcaacccgac ctgatcgggc cccgaccgca ggaggtaccg ctgtgagccg
     9541 ctacgacgcc ccccggctca gagccgcgat ggccgccgtc ccggactacg tccccggccg
     9601 ttccccgcgc cagggctgcg agaacctcaa actctcctcc aacgagaacc cctacccgcc
     9661 gctgccctcg gtcgtcgccg ccgtccgcga acaggccggc cggatcaacc gctaccccga
     9721 cccggcctgc accgccctcg ccgaggcgct cgccgcccgc ctcgacgtcc ccgccgaccg
     9781 gctggtcttc ggcaccggct cggtcgccgt cggccggctg ctcgtccgcg ccaccgccgg
     9841 acccggcgac gaagtcctgt acgcctggcg gtcgttcgag gcctacccga tcatggccga
     9901 ggtctgcggc gcgacctccg tccgggtgcc gctgctcgcc gacgaacgcc acgacctcga
     9961 tgccatggcc gacgcggtca ccgaccgcac ccggctgatc ttcctctgca cccccaacaa
    10021 ccccaccggt accgtcgtcc gccacgccga ggtcgaacgc ttcctcgacc gggtgccgag
    10081 cgacgtgacg gtcgtcctcg acgaggccta caccgagttc gtccgcgacc cggacgccgc
    10141 cgacggcctc gatctccagc gccgccacgg caacgtcgtg ctgctgcgca ccttctccaa
    10201 ggcctacggc ctggccggcc tgcggatcgg ttacgccgtc gcccaccccg agctggcggc
    10261 cgtcctccgc aaggtggggc tgccgttcgg cgtcagcggg ctcgcccagg acgccgcact
    10321 ggcctcgctc gccgccgagg acgaactcct cgaccgggtc gaactgctgg tcaaggagcg
    10381 ggcccgggtc accgccgccc tccgggagag cggcttcgtc ctgccggaca gcgaggccaa
    10441 cttcgtctgg ctccggctcg gcgggcgcac cgccgagttc accgaggcct gcgcggcact
    10501 cggcgccgtg gtccggccgt acgggacgga cggcgtgcgg gtcacggtgg gggagccgga
    10561 ggccaacgac gtggtcctgc gagtcgctgc cgcctggcgg cactagaggg agcaccgata
    10621 ggggcgcggg gacctgcgca gtccggaggt ggacgtcacg acagctcggg ccgggccctg
    10681 atctgcagga cgctccgcct ccgaattgcg cgggtccccg cgctcctggt gaacccgccg
    10741 gtcccgcgcc gccatgcgtc ctctcctcca tgcaggaggg ggcgccaccc gtgcgggtgg
    10801 cgcccctcct gtgtggtgca ccgtcaggcg aagaggcggg cgaattcggt gtggaactcc
    10861 gggaaggtct tgtcgacgca ggccgggtcg tccagcacga tgcccggcac ccgcaggccc
    10921 aggacggaga aggacatcgc gatccggtgg tcgcggtggc agtcgaccgg gccgccggag
    10981 accggaccgg ggtgcacggt gagccggtcc ggtccctccg tca
//
