LOCUS       NZ_CP106798            20675 bp    DNA     linear   CON 01-NOV-2023
DEFINITION  Streptomyces sp. HUAS 15-9 chromosome, complete genome.
ACCESSION   NZ_CP106798
VERSION     NZ_CP106798.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. HUAS 15-9
  ORGANISM  Streptomyces sp. HUAS 15-9
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9258818)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 169.8x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/01/2023 03:42:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,774
            CDSs (total)                      :: 8,679
            Genes (coding)                    :: 8,175
            CDSs (with protein)               :: 8,175
            Genes (RNA)                       :: 95
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 504
            CDSs (without protein)            :: 504
            Pseudo Genes (ambiguous residues) :: 0 of 504
            Pseudo Genes (frameshifted)       :: 260 of 504
            Pseudo Genes (incomplete)         :: 328 of 504
            Pseudo Genes (internal stop)      :: 29 of 504
            Pseudo Genes (multiple problems)  :: 107 of 504
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:51:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7865105
            Orig. end                         :: 7885780
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP106798.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo Ping.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20675
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="24"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20675
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20675
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10675](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10675
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    107..123
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.99"
                     /tool="antismash"
     misc_feature    107..123
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.59"
                     /tool="antismash"
     gene            148..828
                     /locus_tag="N8I87_RS35785"
                     /old_locus_tag="N8I87_35785"
     CDS             148..828
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655970.1"
                     /locus_tag="N8I87_RS35785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35785"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_263214992.1"
                     /transl_table=11
                     /translation="MLYAVSMSSAPPPFPKPQEPFDAPRLLEVGLGPDEPCLRADAARN
                     RARLLEAAARLIAEHGVAGVTMEAVAAAAAVGKGTVFRRFGDRTGLLTALLDHSSRQLQ
                     ADFLGGPPPLGPGAPPVERLRAFGIAVLYRAEEQLDLQLAAQPEPTRRFSHPSVQALRT
                     HVTMLLRQILPDADCELLAQTLLAYLDPALINHLTRQCQMPMERLEAGWTDLVARVTGT
                     EPPA"
     gene            965..2011
                     /locus_tag="N8I87_RS35790"
                     /old_locus_tag="N8I87_35790"
     CDS             965..2011
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134979.1"
                     /locus_tag="N8I87_RS35790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35790"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_263216828.1"
                     /transl_table=11
                     /translation="MRYVMVQIPNTPSSASPAPRSVPTSADVARLAGVSRATVSYVLNN
                     TSAVRISEPTRRRVHEAAKELGYVPHAAARSLRAGHSRMVLMPAPAIPVGPLYGQFLNE
                     LQWALGRLDYTVVQYGTAGLQGDEAARAWAELRPVAVLVPGTGLGPQGVAVLKRAGARA
                     VVTLGPEGVEGAHALLMDHDGVGHCAGAHLYARGRRRIGVVVPEEPGLEAFSRPRLKGL
                     REALHGTDATVTELPLAYDERAAAELAARWRDFDLDAVFAYNDEYAMLLMRALQDEDVR
                     IPEDTAMIGADDLMLGRLLRPRLSTVHIELPSGRDLAELVDRAVRNPGAAPETHKVLGA
                     SMVPRDSS"
     gene            complement(2100..2480)
                     /gene="trxA"
                     /locus_tag="N8I87_RS35795"
                     /old_locus_tag="N8I87_35795"
     CDS             complement(2100..2480)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="trxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006376459.1"
                     /locus_tag="N8I87_RS35795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35795"
                     /product="thioredoxin"
                     /protein_id="WP_263214994.1"
                     /transl_table=11
                     /translation="MSSTVELTKENFDQTVTENEFVLIDFWASWCGPCRMFAPVYEKAA
                     QENPDLVFGKVDTEAQPELAQAFGIQSIPTLMIVRDQVAVFAQPGALPEAALTDVIGQA
                     RKLDMDEVRKNIAEQQGGTQGE"
     misc_feature    2431..2446
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 23.51"
                     /tool="antismash"
     gene            2601..4031
                     /locus_tag="N8I87_RS35800"
                     /old_locus_tag="N8I87_35800"
     CDS             2601..4031
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057649.1"
                     /locus_tag="N8I87_RS35800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35800"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_263214996.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.1e-42, bitscore:
                     143.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETESIAYDVVVLGAGPVGENVADRTRAAGLSTAVVESELVGGE
                     CSYWACMPSKALLRPVIARADARRLPGLSQAAQGPLDTAAVLARRNEYTSHWKDDGQVG
                     WLDGIGADLHRGHGRLAGPRTVTVTGPDGVTRTLTARHAVAVCTGTRAQLPGLPELAEV
                     KPWTSREATAAQAAPGRLIVVGGGVVATEMATAWQALGSRVSLLVRGKGLLSRMEPFAG
                     ELVAESLTEAGAEIRTGTSVQSVTRQNGTVVAITDAGDRIEADEILFATGRAPRTDDIG
                     LDTIGLEPGSWLPVDDSLRVTGSDWLYAVGDVNHRALLTHQGKYQARIAGAVIAARALR
                     VPILETDPWGAHVATADHHAVPQVVFTDPEAAAVGLSLAEAEQAGHRVRAVDVEFSSVA
                     GAGLYADGYRGRARMIVDLDEEILRGVTFVGPGVGELIHSATIAVAGRVPVDRLWHAVP
                     SYPTISEVWLRLLEAYRG"
     gene            complement(4076..4729)
                     /locus_tag="N8I87_RS35805"
                     /old_locus_tag="N8I87_35805"
     CDS             complement(4076..4729)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /GO_process="GO:0018206 - peptidyl-methionine modification
                     [Evidence IEA]"
                     /GO_process="GO:0031365 - N-terminal protein amino acid
                     modification [Evidence IEA]"
                     /GO_process="GO:0043686 - co-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676465.1"
                     /locus_tag="N8I87_RS35805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35805"
                     /product="peptide deformylase"
                     /protein_id="WP_263214998.1"
                     /transl_table=11
                     /translation="MPTPHDHAPRAPLAERVEQLLTADGPLPIVAAGDPVLRRDTEPFD
                     GQLEPALLTRFVEALRITMNAAPGVGLAAPQVGVELRIAVIEDPASVPEEVRLARGRVP
                     QPFRVLVNPSYQPVGTARAAFFEGCLSVPGWQAVVARHAEVRLRAQDEHGRTLDELFTG
                     WPARIVQHETDHLDGMLYLDRAELRSLSSNEAMAERWTQPTPRRAAEELGFRLP"
     gene            complement(4824..5171)
                     /locus_tag="N8I87_RS35810"
                     /old_locus_tag="N8I87_35810"
     CDS             complement(4824..5171)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009344144.1"
                     /locus_tag="N8I87_RS35810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35810"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_263216829.1"
                     /transl_table=11
                     /translation="MDTTYYDHGTAAERWERAQQFFDAKDYARAARVLAGLVEEAPEQT
                     GPRLLLARAYYHSAQLRRAEAELRVIVERDPVEHYARLMLGRTLQRQARHEEAERHLRI
                     ASALAGDFDRG"
     misc_feature    5176..5191
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.13"
                     /tool="antismash"
     gene            complement(5234..5701)
                     /locus_tag="N8I87_RS35815"
                     /old_locus_tag="N8I87_35815"
     CDS             complement(5234..5701)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010043766.1"
                     /locus_tag="N8I87_RS35815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35815"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_263215000.1"
                     /transl_table=11
                     /translation="MTTSAPVVDGRVVGLAHYAARAVLERVLSAHDVTFQQFITLRLAA
                     AADGPVELDALVDGVTGAVKVDASDVYVTVDELIAVGLLAEEEPSRVRITDVGRELYTK
                     GSAETAAAAARIYAGISEEDRAVAGRVLTLVTERADAELAALSEQPATPSK"
     gene            complement(5698..6186)
                     /locus_tag="N8I87_RS35820"
                     /old_locus_tag="N8I87_35820"
     CDS             complement(5698..6186)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010043768.1"
                     /locus_tag="N8I87_RS35820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35820"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_263215001.1"
                     /transl_table=11
                     /translation="MSKGSAGATPGFLVWRLSMKWRVAVDRAVAPLGLTHAQYSLVASL
                     YGMRRSGLRPSQRRLADHTGLEALYVSKLARSLESAGLVERARDPHDPRAVQLALTEEG
                     LEVTRRAIDVVQGLLKQLLEPLGGLDSPRAREFTRDLATLLDAPLDPFSTSDNETEQS"
     misc_feature    6185..6203
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.58"
                     /tool="antismash"
     gene            complement(6277..7242)
                     /locus_tag="N8I87_RS35825"
                     /old_locus_tag="N8I87_35825"
     CDS             complement(6277..7242)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1208: pirin
                     domain-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068410.1"
                     /locus_tag="N8I87_RS35825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35825"
                     /product="pirin family protein"
                     /protein_id="WP_263215002.1"
                     /transl_table=11
                     /translation="MSNLDRHAVPSVCGGRGFVVAEPVRELLSPRQVRLGESTEVRRLL
                     PNLGRRMIGAWCFVDHYGPDDIADEPGMQVPPHPHMGLQTVSWLHEGEVLHRDSTGSLQ
                     TIRPKELGLMTSGRAISHSEESPRPHARFLHGAQLWVALPDAHRDTDPHFEHHPDLPTV
                     TAPGLTATIVLGALDGSASPGTAYTPIVAADLALSHGADVRLPLDPDFEYGVLAMSGEV
                     HVDGVPVLPGSMLYLGCGRTELPLRAESDAGLMLLGGEPFEEELIMWWNFVGRTQAEIE
                     QARADWTTGSRFGEVKGYDGAPLAAPSLPPTPLKPRGRTR"
     gene            complement(7385..7714)
                     /locus_tag="N8I87_RS35830"
                     /old_locus_tag="N8I87_35830"
     CDS             complement(7385..7714)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888485.1"
                     /locus_tag="N8I87_RS35830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35830"
                     /product="TfoX/Sxy family protein"
                     /protein_id="WP_263215004.1"
                     /transl_table=11
                     /translation="MAYDEGLAQRIRERPGGDPDIVEKRMFGGTGFLCRGNMAVGVSGD
                     DLIVRTAPDATDAALARPGARLFDRPGRPMRGWILVAGPALTDDAVLGEWIDEGHGFAA
                     GLPPK"
     gene            7882..8787
                     /locus_tag="N8I87_RS35835"
                     /old_locus_tag="N8I87_35835"
     CDS             7882..8787
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068992.1"
                     /locus_tag="N8I87_RS35835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35835"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_263215006.1"
                     /transl_table=11
                     /translation="MDSSSLDLNLLRTFLAVYRSGSFTGAGQLLGLSQPTVTTQMRTLE
                     RQAGRELFERLPRGVAPTAVADELAARIAAPLDELAAVVSPHPGPGGRTDPVHLAGPAE
                     FLCISVLPALAPLVAEGVRLRVATGLTDPLLDELRAGRHDLVISTTRPRGRTLSAVPLA
                     DEEFVLVAAPVWAERLKRQLAVEGPAVLHLVPLITYAEDLPIARRYWRHVFGRRLSCPA
                     ALTVPDLRGVLAAVTAGAGFTVLPRYLCRDQLASGALVPLHEPADPPINTAFLVQRPGR
                     SENPDVARVRDHLLQIARSW"
     gene            complement(8797..9342)
                     /locus_tag="N8I87_RS35840"
                     /old_locus_tag="N8I87_35840"
     CDS             complement(8797..9342)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984598.1"
                     /locus_tag="N8I87_RS35840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35840"
                     /product="GNAT family protein"
                     /protein_id="WP_263215007.1"
                     /transl_table=11
                     /translation="MYATSLGDDGAVLCPLEPCQAGEFLAHVDRGREFIGRFNGLPDVV
                     KDLESSRAFLRAYAEKAASDTGRIAGILVDGDLVGAVVLRRLDVGQGIAEAGCWLEPSA
                     VGRGLVTRAARVLIDWAVRERGIHRVEWWVSPENAPSIAVARRLGMSKDGVLRESYLYR
                     GKRHDEEIWSVLAPEWLR"
     misc_feature    9344..9359
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            complement(9345..9944)
                     /locus_tag="N8I87_RS35845"
                     /old_locus_tag="N8I87_35845"
     CDS             complement(9345..9944)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676567.1"
                     /locus_tag="N8I87_RS35845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35845"
                     /product="HD domain-containing protein"
                     /protein_id="WP_263215008.1"
                     /transl_table=11
                     /translation="MTLTNVLSIAVDETRDPPLRPLPPRAAALLQRLDAPPRLVAHLRA
                     VHDVAARLAGWAQEHCPALEFDRDAVLFGAATHDIGKTLRRGELSGPGARHEEAGRELL
                     LAHGVEASLARFAGTHASWDVPGVGVEDLLVSLADKVWKNKRVPALEDSVVARLSRAGG
                     RPEWEEFLRLDEVLTAIGEVADRRLAYQMSHPVTRR"
     gene            10001..10675
                     /locus_tag="N8I87_RS35850"
                     /old_locus_tag="N8I87_35850"
     CDS             10001..10675
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: TS_Pyr4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003952725.1"
                     /locus_tag="N8I87_RS35850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35850"
                     /product="hypothetical protein"
                     /protein_id="WP_263215009.1"
                     /sec_met_domain="TS_Pyr4 (E-value: 5.6e-30, bitscore:
                     103.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHAVHTVFLLGTGVFWTTAYVLLIRTGSRERTFGMPVVAFATNIS
                     WEFMFAFVRPPSGLGHVINIVWFCFDVAVGYTVVRFGRAEFPYLPDRLFLPALAALLLL
                     AYPGMNYVSEEFDAGDGVLTAFGSNLAMSGMFLAMLAARRGTRGQSVGIALAKLLGTAC
                     ASLTMLSDPDGDPRYDNALMYYLYIGCLVVDLAYVYAVFAVRRAEGAAVPGELAAQSAV
                     QG"
     gene            complement(10683..12557)
                     /locus_tag="N8I87_RS35855"
                     /old_locus_tag="N8I87_35855"
     CDS             complement(10683..12557)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004571 - mannosyl-oligosaccharide
                     1,2-alpha-mannosidase activity [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013682.3"
                     /locus_tag="N8I87_RS35855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35855"
                     /product="glycoside hydrolase family 47 protein"
                     /protein_id="WP_263215011.1"
                     /transl_table=11
                     /translation="MTTPPTSSFPVGPPGARLTRRSLLRTAAGAAAALTALGGPAAASA
                     ASAPGPADPDLAEDVRQEFLTSWTAYRRLTWGHDELRPVSGTGSEFFISGVPLGLTVVE
                     SLDTLYLMELDGELDTAVSWISGNLDFDRNASVQVFETIIRLVGGLLSGYHCTGNALLL
                     TKARDLADRLLPAFTSSPTGAPYRYVNLRTGAVSGSQVPLAELGSNITELGWLSRLTGD
                     PRYFDAAKNALKAPYDRRSSLNLVGTTLDVDTGAWTDATARVDPPVDSYFEYLWDAYQF
                     FGDTEIRGWYETLTSAVLQRLGETYDGRLWFRSVNMNSGALVNRRQSELSAFYAGLLAQ
                     GGNLNEGESYHSSWAAALESFRLPPEKIDYATLSATSTQYQLRPEYVDSALFLWLLTGK
                     EVYRDRAKWLWSAQKSHCKVTNGYSIVSDMTTTPTTKGDLTPAYWFSENMKYFYLLWSG
                     APRFDYTANYLTTEGNVLRGANRVAAPAPSGTFRLVNRATGRAVDVSGASTADGGAVIA
                     WTPHSGADQSWIATTSGGLTKLTSLNSGKVLEVPRSSTADGTALNQWAHNGSATQQWTL
                     QAMGGGYQRLVNRNSGKALDVDGTANGAAVVQRTAGDAASQQWRLEKV"
     misc_feature    complement(12581..12592)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.52"
                     /tool="antismash"
     gene            12959..13324
                     /locus_tag="N8I87_RS35860"
                     /old_locus_tag="N8I87_35860"
     CDS             12959..13324
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006381239.1"
                     /locus_tag="N8I87_RS35860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35860"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_263215013.1"
                     /transl_table=11
                     /translation="MLEVKTVDKPDERRDFPRGHLEAVHLTGLDFAVATFEPGWRWSES
                     VGPVVGTETCQIHHNGYVVRGRMHLRMDDGGEGEVGPGDVFVCPPGHDAWVVGDEQCVV
                     YDFAGAMAQDYAKAPGT"
     gene            complement(13392..14363)
                     /locus_tag="N8I87_RS35865"
                     /old_locus_tag="N8I87_35865"
     CDS             complement(13392..14363)
                     /NRPS_PKS="Domain: PKS_ER (11-321). E-value: 7.6e-48.
                     Score: 155.1. Matches aSDomain:
                     nrpspksdomains_N8I87_RS35865_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019883954.1"
                     /locus_tag="N8I87_RS35865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35865"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_263215015.1"
                     /sec_met_domain="ADH_N (E-value: 1.2e-08, bitscore: 33.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3e-15, bitscore:
                     55.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAVVQDRYGSPDVLELRDVERPVPGDDEVLVRVRAAGLNAYDWH
                     LMRGDPYVARLALGPRAPRARIRGRDFAGEVEAVGRNVAGLRPGDEVFGEVDGTFAEYV
                     CVPDAWVERKPAALTFEQAAALPLAGNTALRGLRDVAGVRPGHHVLVNGASGGVGTFAV
                     QIAKSLGAEVTGVCSTRNVELVRSLGADHVVDYTREDFTRGGRRYDVILDLAASHGISG
                     LRRALTPTGTLVLGSGGSPGQVLGAPVLILKGLVLSPFVRQRLRPLIGPAPSKAVLAKL
                     RELADSGKLAPVIDRTYALAEAPEAIRYLEDVHARGKVVVTV"
     aSDomain        complement(13401..14330)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_N8I87_RS35865_PKS_ER.1"
                     /evalue="7.60E-48"
                     /label="N8I87_RS35865_PKS_ER.1"
                     /locus_tag="N8I87_RS35865"
                     /protein_end="321"
                     /protein_start="11"
                     /score="155.1"
                     /tool="antismash"
                     /translation="PDVLELRDVERPVPGDDEVLVRVRAAGLNAYDWHLMRGDPYVARL
                     ALGPRAPRARIRGRDFAGEVEAVGRNVAGLRPGDEVFGEVDGTFAEYVCVPDAWVERKP
                     AALTFEQAAALPLAGNTALRGLRDVAGVRPGHHVLVNGASGGVGTFAVQIAKSLGAEVT
                     GVCSTRNVELVRSLGADHVVDYTREDFTRGGRRYDVILDLAASHGISGLRRALTPTGTL
                     VLGSGGSPGQVLGAPVLILKGLVLSPFVRQRLRPLIGPAPSKAVLAKLRELADSGKLAP
                     VIDRTYALAEAPEAIRYLEDVHARGKVVV"
     CDS_motif       complement(13866..13928)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_N8I87_RS35865_0001"
                     /evalue="1.20E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="N8I87_RS35865"
                     /protein_end="166"
                     /protein_start="145"
                     /score="17.9"
                     /tool="antismash"
                     /translation="GHHVLVNGASGGVGTFAVQIA"
     gene            complement(14555..15529)
                     /locus_tag="N8I87_RS35870"
                     /old_locus_tag="N8I87_35870"
     CDS             complement(14555..15529)
                     /EC_number="4.4.1.-"
                     /GO_function="GO:0016846 - carbon-sulfur lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068445.1"
                     /locus_tag="N8I87_RS35870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35870"
                     /product="D-cysteine desulfhydrase family protein"
                     /protein_id="WP_263215017.1"
                     /sec_met_domain="PALP (E-value: 1.4e-47, bitscore: 161.4,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPPVELGTFPTPVEPAPRLAAALGLGPDDLWIKRDDLTGLGGG
                     GNKIRKLEWTLGAALAEGADTLVTTGAPQSNHARLTAAAGARLGLDVVLVLRGSPGVSR
                     SGNLALDGLFGARLVWAGEVDRAGLDALADEVCERLRKNGSRPALVPFGGSSALGARGY
                     VRCGEELRRQVPDPRTVVVALGSGGTMAGLVASLGTEAVLGVDVGALPDPAAAVAKFAA
                     PLTTQAVTPDRLRVRRDQVGDGYATLTAPAAEALRLAARTEGLVLDPIYTSRALAGLTA
                     AVQDGDIRPGERTVFIHTGGLPGLFGHAKAVAYAEEGIVTHEA"
     gene            complement(15593..16951)
                     /locus_tag="N8I87_RS35875"
                     /old_locus_tag="N8I87_35875"
     CDS             complement(15593..16951)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995783.1"
                     /locus_tag="N8I87_RS35875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35875"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_263215018.1"
                     /transl_table=11
                     /translation="MSTPGGVTERLTGLVGALRAHGVRVGTGESVDAARAVEALGFADR
                     ELLREGLAATLLHGTGQRAVFDPVFDLYFPRRVGAPGTRSTDREELRDRLAKALAADDR
                     DMMARLAAEAVDGLGGYGSSPESDGWSSYQTLDRLRPQTLLARVRMDVRQRDGGAGFAD
                     RLLDDEIRRRIEAFRGMVAAEARRRVAERRDRDMIARRAVRPTADRVDFLFAGRDQLAE
                     LRRTVQPLARKLATRLAARRRRAARGTIDLRRTLRGSLSTGGVPMRPVLRRRRPVRPEL
                     VLLCDVSGSVSGFSDFTMLLVQALHDQFSKVRVFAFVNRIDEVTGLLDHGRADPEGLSA
                     RIRAEATLTGWHGSSDYGVALGEFAERYGDAVGPRTTVFVLGDARTNMSDPNLPAVRRI
                     AERACRVYWLNPEQRSQWGTGDSAAPAYAELVEMHECRTARQLGGLVTRLLPV"
     gene            complement(16948..17805)
                     /locus_tag="N8I87_RS35880"
                     /old_locus_tag="N8I87_35880"
     CDS             complement(16948..17805)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676571.1"
                     /locus_tag="N8I87_RS35880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35880"
                     /product="MoxR family ATPase"
                     /protein_id="WP_263215019.1"
                     /transl_table=11
                     /translation="MFTSVDDVSARLAETGYLASPAVATTVFLADRLGKPLLVEGPAGV
                     GKTELAKAVAQVADARLVRLQCYEGVDESRALYEWNHAKQLLRITAGRDETWDETRTDI
                     FSEEFLLARPLLTAIRGDDPKVLLIDETDKADVEVEGLLLEVLSDFQVTVPELGTIAAT
                     RRPFVVLTSNASRELSEALRRRCLFLHIGFPDEELERRIVRLKVPGLGEALAESVVRVI
                     GALRAMDLRKVPSVAETIDWARTLLALGADTLDETVVRDSLGVILKHQDDVLKAAAKLD
                     LDNL"
     misc_feature    17788..17803
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     misc_feature    complement(17891..17906)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            18026..18925
                     /locus_tag="N8I87_RS35885"
                     /old_locus_tag="N8I87_35885"
     CDS             18026..18925
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655910.1"
                     /locus_tag="N8I87_RS35885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35885"
                     /product="hypothetical protein"
                     /protein_id="WP_263215020.1"
                     /transl_table=11
                     /translation="MLGARTDTKADGLANLVEPGREAAYEQFIVGCPGQHMNLQLIHGE
                     AQRSFEYETRQSLRITVGCVLGNVLRDPRLAGGECDRHLKEYLNKEIAGLRARIDQDCA
                     LAVSRGINVGLSLGALISLVLLSAPLVVGAAGLLDVLSVDIGCSDRWNLMGAFVCGGVG
                     AFGAVLSVLVRLRRNGEALVRRRTNGDRGTVAPGQLARGMRHEGVYRVFVGWILALAVY
                     FLLNADIVQVIDTPATTGEICAAHADGAGTAFWGFWCAVGFLAGFNERWAFGLLDRSRT
                     DRRDQPPRQAPTTDTSGS"
     gene            complement(18954..19595)
                     /locus_tag="N8I87_RS35890"
                     /old_locus_tag="N8I87_35890"
     CDS             complement(18954..19595)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040714.1"
                     /locus_tag="N8I87_RS35890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35890"
                     /product="lactate utilization protein C"
                     /protein_id="WP_263215021.1"
                     /transl_table=11
                     /translation="MSSRERILGRVERALADVPRDDTPYEQAVPRDYLREHGERTGTET
                     VDVLAENLADYRALVHRCTAAELPSVIAGLLAARESASVLVPAGLDEAWLAATEVARVA
                     DRPDSTPQELDRVDSVVTACAVAIAETGTLVLDGGPDQGRRRITLVPDHHICVVRVPGQ
                     VVSAVPQALERLDPTRPLTWISGPSATSDIELDRVEGVHGPRTLEVVLVN"
     misc_feature    complement(20535..20549)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.37"
                     /tool="antismash"
ORIGIN
        1 gaaccggcgc gaaggctgcc gacgagcgcg aggatacgga cggacatggg gaactccagg
       61 gggctgaaac ggtgcggtca cgatccggac cggggtccgc ttatcgttgt aacaccataa
      121 ccggaccacg gtccagtttt cttcccggtg ctttacgctg tctccatgtc cagcgctccg
      181 ccgcccttcc cgaagcccca ggagcccttc gacgcgcctc ggcttctgga ggtcggcttg
      241 gggcccgatg agccgtgcct gcgcgccgac gcggcccgca accgcgcccg gctgctggag
      301 gccgcggccc ggctgatcgc cgagcacggg gtggccgggg tcacgatgga ggcggtggcc
      361 gcggccgccg cggtgggcaa ggggaccgtc ttccggcgct tcggcgaccg caccggcctg
      421 ctgacggcgc tgctcgacca ctcgtcgcgg caactgcagg ccgacttcct cggcggcccg
      481 ccgccgctgg gccccggggc gccgcccgtc gagcgactgc gcgcgttcgg catcgcggtg
      541 ctgtaccgcg cggaggaaca gctggacctg caactggccg cccagccgga gccgacccgc
      601 cgcttctccc acccctcggt gcaggcgctg cgcacacacg tcacgatgct gctgcggcag
      661 atcctgcccg acgccgactg cgagctcctc gcacagacgc tgctggcgta tctcgacccg
      721 gccctgatca accatctgac caggcagtgc cagatgccca tggagcggct ggaggccggc
      781 tggaccgacc tcgtcgcccg ggtgaccggt acggaaccac ccgcctgacc ccgaacagcc
      841 gctcctcgta ggcggccggc gcggcggcag agctgccggg cacctgtgcc cgttgtgcgc
      901 ccgctctggt gcaatcgtga atgacgttcc cccgccgcga ccgtcgctcg gcgcttctgc
      961 caagatgcgg tacgtcatgg tgcagatacc gaacacgccc tcgtccgcgt cgcccgcacc
     1021 gcgctccgtc cccacgagcg ccgatgtggc ccgcctggcc ggcgtctcgc gcgcgaccgt
     1081 ctcctacgtc ctcaacaaca ccagtgccgt acggatcagc gagcccacgc gccgccgcgt
     1141 ccacgaggcc gcgaaggaac tcgggtacgt gccgcacgcg gccgcccgca gcctgcgcgc
     1201 cgggcacagc cgtatggtcc tgatgcccgc cccggccatc ccggtgggcc cgctctacgg
     1261 ccagttcctc aacgaactcc agtgggcact cggccgcctc gactacacgg tcgtccagta
     1321 cggcaccgca ggactgcagg gcgacgaagc cgcccgcgcc tgggccgagt tgcggccggt
     1381 cgccgtcctg gtgcccggca ccggactcgg cccccaggga gtcgccgtcc tcaaacgcgc
     1441 cggcgcccgc gcggtggtca ccctcggccc cgagggcgtc gagggcgccc acgccctgct
     1501 gatggaccac gacggcgtcg gccactgtgc cggcgcccat ctgtatgccc gtggcaggcg
     1561 ccgcatcggc gtggtcgtcc ccgaggaacc cggcctggag gccttctccc ggccccgcct
     1621 caagggcctg cgcgaggccc tgcacggcac ggacgccacg gtgaccgagc tgcccctcgc
     1681 ctacgacgaa cgggccgccg ccgaactcgc cgcccgctgg cgggacttcg acctggacgc
     1741 ggtgttcgcc tacaacgacg agtacgcgat gctcctgatg cgcgccctgc aggacgagga
     1801 cgtccgcata cccgaggaca ccgccatgat cggtgccgac gacctgatgc tggggcggct
     1861 gctgcggccc cggctcagca cggtccacat cgaactgccg tccggccgcg acctggctga
     1921 actggtcgac cgcgcggtac gcaaccccgg cgcggcaccc gagacgcaca aggtcctggg
     1981 cgcgtcgatg gtcccccggg actccagctg acggctgccg ccgacgtgcc cctgacgggc
     2041 gccgtaccgc tcccggccgt acccctccca ggggcacggc cgttcccggg aagcgcgggc
     2101 tactcgccct gcgtgccgcc ctgctgctcg gcgatgttct tgcggacctc gtccatgtcc
     2161 agcttccggg cctgcccgat gacatcggtc agggcggcct cgggcagcgc gcccggttga
     2221 gcgaacacgg ccacctggtc acggacgatc atcagcgtcg ggatcgactg gataccgaag
     2281 gcctgcgcca gctccggctg ggcctcggtg tccaccttgc cgaacaccag gtccgggttc
     2341 tcctgcgcgg ccttctcgta gaccggggcg aacatacggc acggcccgca ccaggacgcc
     2401 cagaagtcga tcaggacgaa ctcgttctcc gtgaccgtct ggtcgaagtt ctccttggtg
     2461 agctccacgg tgctgctcat gcgtgatccc tacttcctgc tgcggggggc gaaaccgtcc
     2521 gcacaacacg gcggcccggg tacctattcc gcgcgcttac ccatgtggcc accgcgcaca
     2581 ccacccacca gactgacccc atgacggaaa cggaatccat cgcgtacgac gtcgtggtgc
     2641 tcggggccgg acccgtgggg gagaacgtgg ccgaccgcac ccgcgcggcc ggactgtcca
     2701 ccgcggtcgt ggagagcgag ctggtcggcg gcgaatgctc gtactgggcg tgcatgccca
     2761 gcaaggccct gctgcgcccg gtcatcgccc gcgccgacgc ccgccgcctg cccggcctga
     2821 gccaggccgc ccagggcccc ctcgacacgg ccgccgtcct ggcccgacgc aacgaataca
     2881 cctcgcactg gaaggacgac ggccaggtgg gctggctgga cggcatcggc gccgacctgc
     2941 accgcggcca cggccgcctc gccggacccc gcacggtcac cgtgaccggc cccgacggcg
     3001 tgacgaggac gctcaccgcg cggcacgccg tcgccgtctg caccggcacc cgcgcccagc
     3061 tgcccggcct gcccgagctc gccgaggtga agccctggac cagccgcgag gccaccgccg
     3121 cgcaggccgc ccccggccgg ctgatcgtgg tgggcggcgg tgtggtcgcc accgagatgg
     3181 ccaccgcctg gcaggccctc ggatcccggg tcagcctgct ggtccgcggc aagggcctgc
     3241 tgtcccgcat ggagcccttc gccggggaac tggtcgccga gtccctcacc gaggccggcg
     3301 ccgagatccg caccggcacc tccgtgcagt ccgtgaccag gcagaacggc accgtcgtgg
     3361 cgatcaccga cgccggcgac cgcatcgagg ccgacgagat cctcttcgcc accggccgcg
     3421 ccccgcgcac cgacgacatc ggcctcgaca cgatcggcct ggaacccggc tcctggctgc
     3481 cggtcgacga cagcctccgc gtcaccggca gcgactggct ctacgcggtc ggcgacgtca
     3541 accaccgcgc cctgctcacc caccagggca agtaccaggc ccgcatcgcg ggcgccgtga
     3601 tcgctgcccg cgccttgcga gtcccgatcc tggagacgga cccctggggc gcccacgtcg
     3661 ccaccgccga ccaccacgcc gtaccgcagg tcgtcttcac cgaccccgag gccgccgccg
     3721 tgggcctctc cctggcggag gcggaacagg ccggacaccg tgtccgcgcc gtcgacgtcg
     3781 agttctcctc ggtggccgga gcaggcctgt acgccgacgg ctaccgcggc cgcgcccgca
     3841 tgatcgtcga cctggacgaa gagatcctgc gcggcgtcac cttcgtgggc ccgggagtcg
     3901 gcgagctgat ccactcggcg acgatcgcgg tcgccggccg ggtcccggtc gaccgcctgt
     3961 ggcatgcggt gccgtcgtat ccgacgatca gcgaggtgtg gctgcggttg ctggaggcgt
     4021 accggggcta ggggggtgtc gttcggatca tcccggcgtc gcgggccctg ccggttcacg
     4081 gcagccggaa gcccagctcc tcggccgccc ttcgcggtgt cggctgcgtc caccgctccg
     4141 ccatcgcctc gttcgaggac agcgagcgga gttccgcgcg gtcgaggtag agcatgccgt
     4201 cgaggtggtc cgtctcgtgc tggacgatcc gggcgggcca gccggtgaag agctcgtcga
     4261 gtgtgcggcc gtgctcgtcc tgggcgcgaa gccgcacctc ggcgtgccgg gccaccaccg
     4321 cctgccagcc cgggacgctc aggcagccct cgaagaacgc cgccctggcg gtgccgaccg
     4381 gctggtacga cgggttgacc aggacgcgga acggctgcgg cacccggccc cgggccagcc
     4441 gtacctcttc cggtaccgac gccggatcct cgatgaccgc gatccgcagt tccacgccga
     4501 cctgcggcgc ggctagcccg acgcccgggg ccgcgttcat ggtgatgcgc agggcctcga
     4561 cgaagcgcgt cagcagggcg ggctccaact gcccgtcgaa cggctcggtg tcgcgcctca
     4621 gcaccgggtc gccggccgcg acgatgggca acggaccgtc agcggtgagg agttgctcga
     4681 cccgctcggc gaggggcgca cgaggggcat ggtcatgggg agtcggcatc gcgtcagcat
     4741 gacacgacac tgcgccctgt ccggaccaac gggggcccgg ttcctggtcg gtgaaccggg
     4801 cccccgtgta ccgggtgccg ttctcagccg cggtcgaagt cgcccgcgag cgccgaggcg
     4861 atccgcaggt gccgctccgc ctcctcgtgc cgtgcctgcc gctggagcgt gcggcccagc
     4921 atcagccggg cgtagtgctc cactgggtcg cgctcgacga tgacacgcaa ctcggcctcc
     4981 gcgcggcgca gttgggccga gtggtagtag gcccgcgcca gcagcagccg gggtccggtc
     5041 tgctccggcg cctcctcgac cagcccggcc aggacgcgtg ccgctcgcgc gtagtccttg
     5101 gcgtcgaaga actgctgggc gcgctcccag cgctccgccg cggttccgtg gtcgtagtac
     5161 gtcgtgtcca tctgggtttc cactcgtgac ctccttcgag gccgacaacg gaacccgatg
     5221 gttcaatatt ccactacttg ctcggggtgg ccggttgctc gctcagggcg gccagctccg
     5281 cgtcggcccg ctccgtgacc agcgtcagca cccggcccgc gacggcccgg tcctcctcgg
     5341 agataccggc gtagatccgg gcggcggccg ccgcggtctc ggcggagccc ttggtgtaca
     5401 actcccgccc gacgtccgtg atccgcacac gggacggctc ctcctcggcg agcagcccca
     5461 cggcgatcag ctcgtcgacc gtgacgtaca catcggacgc gtcgaccttc acggcgccgg
     5521 tgacgccgtc gacgagcgcg tcgagctcga ccgggccgtc cgccgcggcg gccaggcgca
     5581 gggtgatgaa ctgctggaag gtgacgtcgt gcgcggacag gacgcgttcc aggacggcgc
     5641 gcgcggcgta gtgggccagg ccgacgacgc ggccgtcgac gacgggtgcg ctggtggtca
     5701 tgactgctcc gtctcgttgt cggacgtgct gaacggatcg agtggtgcgt cgagcagggt
     5761 tgccaggtcc cgggtgaact cccgggcccg cgggctgtcg agcccgccga gcggctccag
     5821 cagctgcttc aggagtcctt ggacgacatc gatcgcccgc cgggtgacct cgaggccctc
     5881 ctcggtgagt gccagctgta cggcacgggg gtcgtgcgga tccctggcgc gttcgacgag
     5941 gccggccgac tccaggctgc gggccagctt ggacacgtac agggcctcca gtccggtgtg
     6001 gtcggccagg cggcgctggc tgggccgcag tccggagcgt cgcatgccgt acagggacgc
     6061 gacgagcgag tactgcgcgt gggtgagtcc gagcggagcc accgcgcggt cgaccgcgac
     6121 ccgccacttc atcgacagcc gccacaccag gaagccgggc gtggcccctg cggaaccttt
     6181 gctcatggcg gatacagtac atggctacta tgtccatggc tactatttat ggcgtgtgaa
     6241 agctcagggc gaccgcggca cggccccggg ggcccgctac cgcgtgcggc ctcgcggctt
     6301 caagggcgtc ggcggcaggc ttggcgccgc cagcggagcg ccgtcgtacc ccttgacctc
     6361 accgaagcga gagcccgtcg tccagtccgc gcgggcctgc tcgatctccg cctgggtacg
     6421 cccgacgaag ttccaccaca tgatcagctc ttcctcgaac ggctcaccgc cgagcagcat
     6481 cagccccgcg tcggactcgg cgcgcagcgg cagttcggtg cgtccgcagc cgaggtagag
     6541 catcgagccc ggcagcacgg gcaccccgtc gacgtgcacc tcgccggaca tcgccaggac
     6601 gccgtactcg aagtcggggt cgaggggcag ccggacgtcg gcgccgtggc tgagcgcgag
     6661 gtcggcggcg acgatcggtg tgtacgccgt accgggcgag gccgagccgt cgagggcgcc
     6721 caggacgatc gtcgccgtga gaccgggggc ggtgaccgtg ggcaggtcgg ggtggtgctc
     6781 gaagtggggg tcggtgtcgc ggtgcgcgtc cggcagcgcg acccacagct gtgcgccgtg
     6841 caggaagcgg gcgtgcggcc gcgggctctc ctcggagtgg ctgatggccc ggcccgaggt
     6901 catcagcccg agctccttcg gcctgatcgt ctgcaggctg ccggtcgagt cgcggtgcag
     6961 cacctcgccc tcgtgcagcc agctcaccgt ctgcagtccc atgtgcggat gcggcgggac
     7021 ctgcatgccc ggctcgtcgg cgatgtcgtc cgggccgtag tggtcgacga agcaccacgc
     7081 gccgatcatg cggcgcccca ggttgggcag cagccgccgt acctcggtcg actcgcccag
     7141 ccgcacctga cgaggactca gcagctcccg gacgggttcc gcgacgacga aaccccggcc
     7201 gccgcacaca ctggggaccg catgacggtc aagattgctc atgccgcaca acctagcccc
     7261 ggcgcggcct caccggcaga ccaacgcctc ggtacggccg cccgttcggc cggtcacgca
     7321 cccgccgacg tcgccccggc agcccgtggc catgccgtcg tggtcctcgc ccgggacgcg
     7381 cgcctcactt gggcggcagg cccgccgcga agccgtgtcc ctcgtcgatc cactcgccca
     7441 gtaccgcgtc gtcggtcagg gccgggccgg cgaccaggat ccagccgcgc atcggacgcc
     7501 cgggccggtc gaagaggcgg gcacccgggc gggccagggc cgcatccgtg gcgtcggggg
     7561 cggtgcgcac gatcaggtcg tcaccgctca cgcccacggc catgttgccg cggcacagga
     7621 agccggtccc gccgaacatc cgcttctcca cgatgtccgg atccccgccc ggccgctccc
     7681 ggatccgctg ggccagtcct tcgtcgtacg ccatgaggag cctcgcttcc ggccgggcca
     7741 ccgtggatgc cgtcgcaccg gcctgtcgtg gctccaggat ccgcgatcgt cggcgtcgaa
     7801 ggcggcgagc cataggcaat cgccgagaca gccgctgtcc ggcattggaa gatctatggg
     7861 tcgcggacca tactcggacg ggtggacagc tcctccctcg acctgaacct gctgcgcacc
     7921 ttcctggccg tctaccggtc gggctccttc accggtgccg ggcagttgct ggggctgtcg
     7981 cagcccacgg tgaccaccca gatgcgcacc ctggagcggc aggccgggcg ggagctgttc
     8041 gagcggcttc ccaggggcgt cgcgccgacg gccgtcgccg acgagctggc cgcgcggatc
     8101 gccgcaccgc tcgacgaact cgcggccgtg gtaagcccgc accccgggcc gggcggccgc
     8161 accgacccgg tccatctggc cgggcccgcg gagttcctgt gcatcagtgt gctgcccgcc
     8221 cttgcaccgc tggtggcgga gggcgtacgg ctgcgcgtgg cgaccgggct cacggacccg
     8281 ctgctggacg aactgcgcgc gggccgccac gacctggtga tctccacgac ccgtccgcgc
     8341 ggccgcactc tgagcgcggt cccgctcgcg gacgaggagt tcgtgctggt cgccgctccc
     8401 gtgtgggccg agcggctgaa acggcaattg gccgtcgagg gccccgccgt gctgcatctg
     8461 gtgcccctga tcacctacgc cgaggacctt ccgatcgccc gccgctactg gcgccatgtc
     8521 ttcggccggc ggctctcctg ccccgctgcc ctgacggtgc ccgatctgcg cggcgtcctg
     8581 gcggcggtga ccgcgggcgc gggcttcacc gtgctgcccc gctacctctg ccgcgatcag
     8641 ctggcctccg gcgccctcgt accgctccac gagcccgccg atccgcccat caacacggcc
     8701 ttcctggtcc agcgccccgg ccggtccgag aaccccgacg tggcccgcgt ccgcgaccat
     8761 ctgctgcaga tcgcgcggtc ctggtagcga ccgccgtcag cggagccact ccggtgccag
     8821 caccgaccag atctcctcgt cgtgccgttt cccccgatag aggtaactct cccgcagtac
     8881 cccgtccttg ctcatcccga gccgccgggc aacggcgatg ctcggcgcgt tctccgggga
     8941 cacccaccac tcgacgcggt ggattccgcg ctccctgacc gcccagtcga tgagcacgcg
     9001 cgcggcgcgc gtcaccagcc ccctgcccac cgccgagggc tccagccagc agcccgcctc
     9061 ggcgatcccc tgcccgacgt ccagccggcg cagcacgacc gcgccgacca gatcgccgtc
     9121 caccaggatc ccggcgatcc gcccggtgtc cgacgcggcc ttctccgcgt acgcgcgcag
     9181 gaacgcccgg ctcgactcca ggtccttgac gacgtccggc agcccgttga accggccgat
     9241 gaactcccgc ccccggtcca catgggccag gaactcccct gcctgacacg gctcgagggg
     9301 gcagagcacg gcgccgtcgt cgcccaggga agtcgcgtac atcgtcacct tcgtgtcacg
     9361 ggatgggaca tctggtacgc cagcctacgg tcggcgacct caccgatggc cgtgaggacc
     9421 tcgtccagcc gcaggaactc ctcccactcc ggccgaccgc cggcccggga gagccgcgcc
     9481 acgaccgagt cctccagggc ggggacccgc ttgttcttcc agaccttgtc cgccaggctc
     9541 accagcaggt cctccacccc gacccccggg acgtcccagg acgcgtgcgt accggcgaac
     9601 cgggccagtg acgcctcgac cccgtgcgcc agcaggagtt cacgtccggc ctcctcgtgc
     9661 cgcgcgccgg gaccggagag ctcgccgcgg cgcagggtct tgccgatgtc atgggtggcg
     9721 gccccgaaga gcaccgcgtc ccggtcgaac tccagtgccg ggcagtgttc ttgggcccag
     9781 ccggccagcc gtgccgcgac atcgtgcacc gcccggaggt gggcgaccag gcggggcggg
     9841 gcatcaagtc gttgcagcag cgcggcggcc ctcggcggaa gcggtctcag cggcgggtcc
     9901 cgggtttcgt ccacggcgat cgagagcacg ttcgtgaggg tcaccgtgcc agagtagtca
     9961 ccggcgcgag ccggaccgta acggcctacg gagggtatcc atgcacgcgg tgcacacggt
    10021 gtttctcctg gggacgggag tcttctggac caccgcctac gtgctgctga tccggaccgg
    10081 atcacgggag cggacgttcg gcatgcccgt cgtggcgttc gccaccaaca tcagctggga
    10141 gttcatgttc gccttcgtgc ggccgccgtc cggtctcgga cacgtcatca acatcgtgtg
    10201 gttctgcttc gacgtggccg tcggctacac cgtcgtccgc ttcggccggg ccgagttccc
    10261 ctacctgccc gaccggttgt tcctgcccgc gctggccgca ctgctgctcc ttgcctatcc
    10321 gggcatgaac tacgtctccg aggagttcga cgcgggcgac ggcgtcctca ccgcgttcgg
    10381 cagcaacctg gcgatgtccg ggatgttcct ggcgatgctg gccgcgcgcc gtgggacgcg
    10441 cggccagtcc gtgggcatcg cgctggccaa actcctgggc accgcctgcg cctccctgac
    10501 gatgctcagc gaccccgacg gggacccgcg ctacgacaac gccctgatgt actacctcta
    10561 catcggctgc ctcgtcgtcg acctcgccta cgtgtacgcg gtgttcgccg tacgccgtgc
    10621 cgaaggcgcc gccgttcccg gcgagttggc cgcgcagagt gccgtccagg gctgacgcgc
    10681 cctcacacct tctccagccg ccactgctgc gaggccgcgt caccggccgt ccgctgcacc
    10741 accgccgcgc cgttggcggt gccgtcgacg tccagggcct tgccgctgtt gcggttgacg
    10801 aggcgctggt agccgccgcc catcgcctgg agcgtccact gctgggtggc gctgccgttg
    10861 tgcgcccact ggttcagcgc cgtgccgtcc gcggtggagg agcgcggcac ctccagcacc
    10921 ttgccgctgt tgaggctggt cagcttggtg aggccgcccg aagtggtggc gatccagctc
    10981 tggtcggcgc cggagtgcgg ggtccacgcg atcaccgcgc caccgtccgc cgtcgatgcc
    11041 ccgctcacgt ccacggcccg cccggtcgcc cggttgacca gccggaaggt gccgctcggc
    11101 gcgggcgcgg cgacccggtt ggcaccgcgc agcacattgc cctcggtggt caggtagttg
    11161 gcggtgtagt cgaagcgcgg cgcaccggac cacagcagat agaagtactt catgttctcc
    11221 gagaaccagt acgccggtgt cagatccccc ttggtcgtcg gggtcgtcgt catgtccgac
    11281 acgatcgagt agccgttcgt gaccttgcag tggctcttct gcgcgctcca gagccacttg
    11341 gcgcggtccc ggtagacctc cttgccggtc agcagccaca ggaacagcgc ggagtccacg
    11401 tactcggggc gcagctggta ctgcgtgctg gtcgccgaga gcgtcgcgta gtcgatcttc
    11461 tccggcggca gccggaacga ttccagcgcc gccgcccacg aggagtggta ggactcgccc
    11521 tcgttcaggt tgccgccctg ggcgagcaac ccggcgtaga acgcgctgag ttcggactgt
    11581 ctccggttga ccagcgcccc gctgttcatg ttcacggacc tgaaccacag ccgcccgtcg
    11641 taggtctccc cgagccgttg caggacggcc gaggtaaggg tctcgtacca gccgcggatc
    11701 tcggtgtcgc cgaagaactg ataggcgtcc cacagatact cgaagtagga gtccacgggc
    11761 gggtccaccc gggcggtggc gtcggtccag gcgccggtgt cgacgtcgag cgtcgtcccg
    11821 accaggttca gcgaggagcg ccggtcgtac ggggccttca gggcgttctt ggccgcgtcg
    11881 aagtatctcg ggtcgccggt cagccgggac agccagccca gttcggtgat gttgctgccg
    11941 agctcggcga gcggcacctg gctgccgctg accgcgcccg tgcgcagatt gacgtaccgg
    12001 tacggcgccc cggtcggcga cgatgtgaag gccggcagca gccggtcggc cagatcgcgg
    12061 gccttggtca gcaggagcgc gttgccggtg cagtggtagc cggagaggag accgccgacc
    12121 agtcggatga tcgtctcgaa gacctgcaca ctcgcgttgc ggtcgaagtc caggttcccg
    12181 ctgatccagg agacggccgt gtcgagttcg ccgtccagct ccatcagata gagcgtgtcc
    12241 agcgactcca cgacggtcag ccccagcggc accccgctga tgaagaactc ggagccggtg
    12301 ccggacaccg ggcgcagctc gtcgtggccc caggtcagcc gccggtaggc ggtccaggag
    12361 gtgaggaact cctggcgcac gtcctcggcg aggtcggggt cggccggtcc gggcgcggac
    12421 gctgcggatg ccgctgcggg tccgcccagc gcggtgagcg cggccgcggc cccggctgcc
    12481 gtgcgcagca gggagcggcg cgtgagccgg gcgcccggcg gtccgaccgg gaaactgctg
    12541 gtggggggtg ttgtcatgag gggcctccgt ccagggcgtt gacaacgttg tctcggcatg
    12601 gttcctggct cagcatgcgg ggatggcacg ggattttcgg tgaacggacc gtgcgtcgcg
    12661 gggagtcggg cgtacgtgcg cgggtcggcc gaacgggggg agcggagcgc ggacggccga
    12721 gtctggggtg aattgcatga gcatgtcaat cctgcgcgcg agtcgagcgc gagtcgattt
    12781 cgacgcccca ggagccccgc cggactccgc cgttccccga atggcggcgc ccagttgacg
    12841 ggcagacgat ggagtggtgg ggcacggccg ccgtccgagc gcccggtgcc gcccggggcc
    12901 gccgggagac ggagaccggc cccggccgtg gtgagcggcc ggaagggagg acaccgtcat
    12961 gttggaagtg aagacggtcg acaagcctga cgagcggcgc gacttccccc gcggccacct
    13021 cgaagcggtc catctgaccg gactcgactt cgccgtggcc acgttcgagc cgggctggcg
    13081 ctggtcggag tccgtgggcc cggtcgtggg caccgagacc tgccagatcc accacaacgg
    13141 ctatgtggtc cgagggcgga tgcatctgcg catggacgac ggcggcgagg gcgaggtcgg
    13201 ccccggcgac gtcttcgtgt gcccgcccgg ccacgacgcc tgggtcgtgg gcgacgaaca
    13261 gtgcgtggtg tacgacttcg cgggggccat ggcacaggac tacgcgaagg ctccggggac
    13321 ctgagcggat cccgatgtgc cccgcggtgc gtgtggctcc gcggggcacc ggcatgaacg
    13381 ggccggcccg gtcacaccgt gacgacgacc ttcccccggg cgtgcacgtc ctccaggtac
    13441 cggatggcct cgggcgcctc ggcgagcgcg tacgtccggt cgatcaccgg ggccagcttc
    13501 ccggagtcgg ccagctcccg cagcttcgcc agcaccgcct tgctgggcgc cgggccgatg
    13561 agcgggcgca gccgctggcg tacgaagggg gagaggacga gccccttgag gatgaggacg
    13621 ggcgccccga ggacctgccc cgggctgccc ccgctgccga ggaccagcgt cccggtgggt
    13681 gtcagggcgc gccggaggcc ggagatgccg tggctcgccg cgaggtcgag gatcacgtcg
    13741 taccgtcgcc cgccgcgtgt gaagtcctcg cgcgtgtagt cgacgacgtg gtccgcgccc
    13801 agtgagcgga ccagttcgac gttgcgtgtg ctgcacacgc cggtcacctc ggcgccgagt
    13861 gacttggcga tctgcacggc gaacgtgccg accccgccgg aggccccgtt gaccagcaca
    13921 tggtggcccg gccgcacccc cgccacgtca cgcagtccgc gcagggcggt gttcccggcc
    13981 agcggcaggg ccgccgcctg ctcgaaggtg agggcggcgg gcttgcgctc cacccaggcg
    14041 tccgggacgc acacatactc cgcgaaggtg ccgtcgacct cgccgaacac ctcgtcgccg
    14101 ggccggagac ccgccacgtt ccggccgacc gcctccacct cgcccgcgaa gtcgcggccc
    14161 cggatccggg cgcggggcgc gcggggcccc agcgccagcc gggccacgta cgggtcaccg
    14221 cgcatcaggt gccagtcgta cgcgttcagc ccggcggccc gcacccgcac cagcacctcg
    14281 tcgtcaccgg gcacgggcct ttccacgtcc ctgagctcca gcacgtccgg tgagccgtac
    14341 cggtcctgga cgactgcctt catgtcatcg cccccttgcc acgtactggc aggttagggg
    14401 caggcccgcc gacagggcat cggggaagtg ccgtagttcc ggggaaggag gagcgcgggt
    14461 gcgtgtaagg ggccgggtgc cgtcgaggct cgtctgtcga tgcgggcggc gagccgcagc
    14521 gtcggtgagt gtcgcgtgcc ggggtcgggt gccgtcaggc ctcgtgggtg acgatccctt
    14581 cttcggcgta cgcgacggcc ttcgcgtgtc cgaacaggcc gggtagtccg ccggtgtgga
    14641 tgaacacggt ccgttcgccg ggccggatgt cgccgtcctg gacggcggcg gtcagcccgg
    14701 ccagggcgcg gctcgtgtag atggggtcga ggacgagtcc ctcggtgcgg gcggcgagcc
    14761 ggagtgcctc ggccgcgggg gcggtgagcg tcgcgtagcc gtcgcccacc tggtcgcggc
    14821 gcacccgcag tcggtccggg gtgaccgcct gcgtggtgag cggcgccgcg aacttggcga
    14881 cggcggcggc cgggtcgggc agcgcgccca cgtcgacccc gagcaccgcc tccgtcccga
    14941 gcgaggcgac gagtcctgcc atggtgccgc cggatccgag cgcgacgacc acggtccgcg
    15001 ggtccgggac ctgccggcgc agctcctcgc cgcaccgcac atagccgcgc gcccccagcg
    15061 cgctggaccc gccgaacggg acgagcgcgg gccgggagcc gttcttccgc agccgttcgc
    15121 acacctcgtc cgccagcgcg tccaggcccg cccggtcgac ctcgcccgcc cagaccagcc
    15181 gtgccccgaa caacccgtcg agcgcgaggt tcccggagcg cgacacgccc ggcgagccgc
    15241 gcagcaccag gacgacgtcc aggcccagcc gggcgcccgc ggccgccgtc agccgggcgt
    15301 ggttgctctg cggcgcgccg gtggtcacca gtgtgtcggc cccttccgcg agcgccgcgc
    15361 ccagcgtcca ctccagcttg cggatcttgt tgccgccacc gccgagaccg gtcaggtcgt
    15421 cccgcttgat ccacaggtcg tccgggccga gcccgagcgc ggcggccagc cggggcgccg
    15481 gttccacggg agtggggaag gtgccgagtt ccacgggcgg gtgggtcatg tcgtacgtcc
    15541 tcgtctgcgg gcggatgtgc cgcaagtcga ccacacatcg gccccggccg cctcacaccg
    15601 gcagcagcct cgtgaccagc ccgccgagtt gccgcgccgt gcggcactcg tgcatctcca
    15661 ccagttccgc gtaggcgggc gcggcggagt cgccggtgcc ccattgggag cgctgctcgg
    15721 ggttcaacca gtagacacgg caagcccgtt cggcgatccg gcggaccgcg ggcagattcg
    15781 ggtcgctcat gttcgtacgg gcgtcaccga ggacgaacac cgtcgtgcgc gggccgaccg
    15841 cgtcgccgta gcgctccgcg aactcgccca gggccacgcc gtagtcgctg ctgccgtgcc
    15901 agccggtgag cgtcgcctcc gcgcggatgc gggcgctcag gccctcgggg tcggccctgc
    15961 cgtggtcgag gaggccggtc acctcgtcga tccggttgac gaaggcgaac acccgcacct
    16021 tgctgaactg gtcgtgcagc gcctgcacca gcagcatcgt gaagtcggag aagcccgaca
    16081 ccgagcccga cacatcgcac agcaggacca gttcgggccg caccggacgg cgcctgcgca
    16141 gcaccggccg catcggcaca ccgcccgtcg acagcgaccc gcgcagggtg cggcgcagat
    16201 cgatggtgcc gcgcgcggcc cggcggcgcc gcgcggcaag gcgggtggcc agtttgcggg
    16261 cgagcggctg aacggtcctg cgcagttcgg ccagttggtc ccgaccggcg aacaggaagt
    16321 ccacccggtc ggcggtcggg cgcaccgccc gccgggcgat catgtcccgg tcgcgccgct
    16381 cggcgacccg ccgccgcgcc tcggccgcga ccatcccacg gaacgcctcg atacggcgcc
    16441 ggatctcgtc gtcgagcagc cggtcggcga agcccgcgcc cccgtcccgc tgccggacgt
    16501 ccatccgcac ccgggccagc agcgtctggg ggcggagccg gtcgagggtc tggtacgacg
    16561 accagccgtc cgactccggt gaactcccgt atccgcccag cccgtcgacg gcctccgccg
    16621 ccagccgcgc catcatgtcc cggtcgtccg ccgccagcgc cttagcgagc cggtcgcgca
    16681 gctcctcccg gtccgtggac cgtgtgccgg gcgcgccgac gcgccgcggg aagtagaggt
    16741 cgaagaccgg gtcgaacacg gcccgctggc ccgtcccgtg cagcagcgtc gccgccaggc
    16801 cctcccgcag cagctcccgg tcggcgaacc cgagcgcctc caccgcgcgg gccgcgtcca
    16861 cgctctcccc ggtgccgacc cgcacgccgt gcgcgcgcaa cgccccgacc aggcccgtca
    16921 gccgctcggt gacgccgccg ggggtgctca caggttgtcc aggtccagtt tggcggccgc
    16981 cttgaggaca tcgtcctggt gcttgaggat cacgcccagg ctgtcccgta ccaccgtctc
    17041 gtcgagcgtg tcggcgccca gcgccagcag ggtgcgcgcc cagtcgatcg tctcggcgac
    17101 cgacggcacc ttccgcaggt ccatcgcgcg cagcgcgccg atcacccgca ccacggactc
    17161 ggccagcgcc tcgccgaggc cgggcacctt cagccgtacg atccgccgct ccagctcctc
    17221 gtccgggaag ccgatgtgca ggaacagaca gcgccggcgc agggcctcgg acagctcacg
    17281 gctggcattg gaggtcagta cgacgaacgg gcggcgggtg gccgcgatgg tgcccagctc
    17341 ggggacggtc acctggaagt cgctgagcac ctccaggagc agcccctcca cctcgacgtc
    17401 ggccttgtcg gtctcgtcga tcagcagcac cttggggtcg tcgccgcgga tggcggtcag
    17461 cagcggacgc gcgagcagga actcctcgct gaagatgtcc gtgcgcgtct cgtcccaggt
    17521 ctcgtccctg ccggcggtga tccgcagcag ctgcttggcg tggttccact cgtacagcgc
    17581 gcgggactcg tcgacgccct cgtagcactg cagccgtacc agccgggcgt ccgctacctg
    17641 ggcgacggcc ttggccagct ccgtcttgcc gacccccgcg gggccctcca ccagcagcgg
    17701 cttgcccagc cggtcggcca ggaagacggt cgtggcgacg gcgggcgacg ccagatagcc
    17761 ggtctcggcg aggcgtgcgg agacgtcgtc tacggaagtg aacaacgggg cctccggctg
    17821 gttcgggttc ggtgtccagg tccctatcta agcgcttgtt cagcgcccct gtcacctggg
    17881 taccgcggtg gtgaccgctc cgtgacgaca gtgaccgtac tggtgccgtg cccgccttcc
    17941 cgtcgggcgg cggtgcgggt acaggttgtc catgacgagc aacgggggct gccgccgatc
    18001 gaggtggcgg agattacgcg acgcggtgct gggcgcccgc accgacacga aggccgacgg
    18061 actggccaac ctggtggaac cgggccgcga ggcggcgtac gagcagttca tcgtcggctg
    18121 tcccggccag cacatgaacc tccagctgat ccacggcgag gcacagcggt cgttcgagta
    18181 cgagacccgg cagtcgctgc ggatcacggt cggctgtgtc ctgggcaatg tactgcgcga
    18241 cccgcggctg gccggcgggg agtgcgacag gcatctcaag gagtacctca acaaggagat
    18301 cgcgggcctg cgggcccgga tcgaccagga ctgcgcgctc gccgtgagcc gcggcatcaa
    18361 cgtcggactc agcctcggcg cgctgatcag cctggtgctg ctgagcgcgc cgctcgtggt
    18421 gggggccgcg gggctgctcg acgtcctgag cgtggacatc gggtgcagcg accggtggaa
    18481 cctgatgggc gccttcgtgt gcggcggggt gggcgcgttc ggcgcggtgc tcagcgtgct
    18541 ggtacggctg cgcaggaacg gggaggcgct cgtccgccgg cggaccaacg gcgaccgtgg
    18601 caccgtggcc ccggggcagc tggcgcgcgg catgcgccac gagggcgtgt accgggtgtt
    18661 cgtcggctgg atcctggccc tggcggtgta cttcctgctc aacgcggaca tcgtgcaggt
    18721 gatcgacacg cccgcgacca ccggcgagat ctgcgccgcc cacgcggacg gggcgggcac
    18781 cgcgttctgg ggcttctggt gtgcggtcgg cttcctggcc ggcttcaacg agcgctgggc
    18841 cttcggcctg cttgaccgct cccggaccga ccgccgtgac cagcccccgc gccaggcgcc
    18901 gaccaccgac accagcggca gctgacccgg aaccgacggc cggggccccg gtgtcagttc
    18961 accagcacga cctccagggt ccgcggcccg tgcacccctt ccacccggtc cagctcgatg
    19021 tcgctggtcg ccgacggccc ggagatccag gtcaacgggc gggtcgggtc caggcgttcc
    19081 agggcctgcg ggacggcgga gacgacctgc ccggggacgc ggaccacgca gatgtgatgg
    19141 tcggggacaa gggtgatccg gcggcgcccc tggtcggggc cgccgtccag cacgagggtg
    19201 cccgtctcgg cgatcgccac cgcgcacgcc gtgaccacgc tgtccacccg gtcgagttcc
    19261 tgcggggtgc tgtccggccg gtcggcgacc cgcgcgacct ccgtggccgc cagccaggct
    19321 tcgtcgagcc cggccgggac cagcaccgag gccgactccc gcgcggccag caacccggcg
    19381 atcaccgaag ggagttcagc ggccgtacag cggtgcacga gcgcccggta gtccgccagg
    19441 ttctccgcga gcacgtccac cgtctccgtc ccggtgcgct cgccgtgctc gcgcagatag
    19501 tcccggggga cggcctgctc gtacggcgtg tcgtcccgcg ggacgtccgc gagcgcgcgc
    19561 tccacccggc ccaggatgcg ttccctgctg ctcacttggc ggcccccttg tcgccgttct
    19621 cgccgctcgt gcgccgccac cagtcacgga agggctcggg aggcacggtc ggcagatcgc
    19681 gggtgccggt ccacgcccgg ccggggcccg ggagcgtacg gggatgcagg cggcgggtgc
    19741 gggaggcgag ccgctggccg gtgcgcaggg cgcccgggtg ggtgaaagcc caacgcgccg
    19801 cgcgcatggc ggcccgctcg gcggcatgcc ccttcgcggg ttgcagcacc accttgttgc
    19861 cgtcccggat cgtccgaccg ccctgcacga cccgctcgcg cagatgcacc agcacctcgg
    19921 ggatgtcgat ggccaccggg cacacctcgt aacaggcccc gcagagcgag gaggcatagg
    19981 ggagggaggc gtcgatctcg ctcgccgtgc cccggagctg ggggctgagg atggcgccga
    20041 tcgggccggg gtagaccgag ccgtacgcat ggccgcccgc acgctcgtac accgggcaca
    20101 cattgagaca cgccgagcag cggatgcagc gcagcgcctg gcgtccgacc tggtcggcga
    20161 gcgtgtcggt gcggccgttg tcgagcagga ccagatggaa ggtgctgggg ccgtcctcgt
    20221 ccgtggtgcc ggtccacatg ctcgtgtacg ggttcatgcg ctcggccgtg gaggagcggg
    20281 ggagggtctg caggaacacc tccaggtccc gccaggccgg cacgatcttc tcgatgccaa
    20341 cgacggagat cagggtctcg ggcagggtca ggcacatccg gccgttgccc tccgactcga
    20401 ccacgaccag tgtgccggtc tcggcgacca tgaagttggc gccggagaca ccgaccttgg
    20461 cgcgcaggaa cttctcccgc agatggaggc gggcggcctc ggccagttcg gcgggcgtgt
    20521 cggtcaggcc ctcgggggcc gggcggcccc actcgcccat ctcggcgcgg aagatgtccc
    20581 ggatctcgcc ccggttgcgg tggatcgccg ggaccaggat gtgcgagggc cggtccttgc
    20641 ccaactgcac gatcagctcg gcgagatcgg tctcg
//
