LOCUS       NZ_CP106798            22260 bp    DNA     linear   CON 01-NOV-2023
DEFINITION  Streptomyces sp. HUAS 15-9 chromosome, complete genome.
ACCESSION   NZ_CP106798
VERSION     NZ_CP106798.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. HUAS 15-9
  ORGANISM  Streptomyces sp. HUAS 15-9
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9258818)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 169.8x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/01/2023 03:42:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,774
            CDSs (total)                      :: 8,679
            Genes (coding)                    :: 8,175
            CDSs (with protein)               :: 8,175
            Genes (RNA)                       :: 95
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 504
            CDSs (without protein)            :: 504
            Pseudo Genes (ambiguous residues) :: 0 of 504
            Pseudo Genes (frameshifted)       :: 260 of 504
            Pseudo Genes (incomplete)         :: 328 of 504
            Pseudo Genes (internal stop)      :: 29 of 504
            Pseudo Genes (multiple problems)  :: 107 of 504
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:51:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7697094
            Orig. end                         :: 7719354
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP106798.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo Ping.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22260
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="23"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22260
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22260
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12260](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12260)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(7..20)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    complement(286..301)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.79"
                     /tool="antismash"
     misc_feature    complement(286..301)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.69"
                     /tool="antismash"
     misc_feature    317..331
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    588..601
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.47"
                     /tool="antismash"
     misc_feature    complement(634..649)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            661..1692
                     /locus_tag="N8I87_RS35100"
                     /old_locus_tag="N8I87_35100"
     CDS             661..1692
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676278.1"
                     /locus_tag="N8I87_RS35100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35100"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_263214821.1"
                     /transl_table=11
                     /translation="MGHPFPIREIARQAGLSEATVDRVLNGRGGVRESTAEEVRRAIAD
                     LDRQRTQVRLVGRTFMVDIVMQAPERFTTAVRAALEAELPSLHPAVLRSRFHFRETGPV
                     RELVATLDRVTRRGSQGVILKAPDVPEVTAAVGRLATAGIPVVTLVTDLPASARMAYVG
                     IDNRAAGATAAYLMGQWLGDRPGHVLTSLSSGFFRNEEEREMGFRGVMRARHPQRTLVE
                     IAEGQGLDTTQYDHVRAALERDPGIRAVYSIGGGNIATLRAFEDLGRECAVFVAHDLDH
                     ENTRLLREHRLSAVLHHDLRHDLREACHLVMRAHGALPPTGPVAPSSIQVVTPYNMPTA
                     PAR"
     gene            complement(1673..2833)
                     /locus_tag="N8I87_RS35105"
                     /old_locus_tag="N8I87_35105"
     CDS             complement(1673..2833)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389147.1"
                     /locus_tag="N8I87_RS35105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35105"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_263214822.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.4e-21, bitscore:
                     76.3, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 4.3e-31,
                     bitscore: 106.4, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDALGVAVVGFGWMGRVHTQAYARVAHHYPGLALRPRLVTVAEE
                     VPGRAEEAAARFGFASTTRDWREVAADPRVRAVSITAPNFLHREIGVAMAAVGKHIWIE
                     KPVGLTAEDARAVADAVAGAGVHGAVGFNYRNAPAVQAARELIASGDIGAVTHVRIRLF
                     SDYAAHPDGALTWRYERERGGSGVLGDLASHGADLARFLLGDIAALTADTAVFVPERAR
                     PTGATAGHARASGGELGPVENEDYVNCLLRFASGARGVLEACRVSVGEQNNYGFEVHGT
                     RGAVFWDFRRMNELALSRGTTYQDQPVSTVYVGPGDGEFAAFQPGAANAMGYDDLKVIE
                     AYRFLRSIAEGRPYGTTLVDAVHSAAVLDAMTRSAETGGWVNVQAP"
     gene            2963..3973
                     /locus_tag="N8I87_RS35110"
                     /old_locus_tag="N8I87_35110"
     CDS             2963..3973
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656304.1"
                     /locus_tag="N8I87_RS35110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35110"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_263214824.1"
                     /transl_table=11
                     /translation="MRPPTIRDVAEQAGVSKSLVSLVLRGSDQVRPEKREAVLRAVREL
                     GYRPNAAARSLSEQRTRTVGVLLNDLRNPWFVDLLDGLNSLLRDNGLHMLLADARLNRR
                     TGHDPIGPFLDLGVDGLVAVGTLPEPAVLGAVAERMPVVVAGAREPELPDVDVVAGDDE
                     TGARLVTEHLIGLGHRRIAHIAGYGAVGELRRRSFEATMRAHGLDAEARIEASDMTEEG
                     GYRTTIRLLSRPDRPSAILAVNDIASVGALSAAEELGLRVPRDVSVTGYDNTSIARLRH
                     VWLTTVDTAPHEVGRRAARCLLDRFERPGGAGRVHLAAPTLEIRGTTAAPPGLTD"
     gene            complement(3963..4307)
                     /locus_tag="N8I87_RS35115"
                     /old_locus_tag="N8I87_35115"
     CDS             complement(3963..4307)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676281.1"
                     /locus_tag="N8I87_RS35115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35115"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_263214826.1"
                     /transl_table=11
                     /translation="MTHSFALHIPDAELEPEPLDPEQIVSGSPEVTGKVVWESEDGRRI
                     RGIWQITPGVVTDTEADELFVVISGSATIEVGGGPTLEVGPGDMAVLREGDRTTWTVHE
                     TLRKAYAINL"
     misc_feature    complement(4261..4276)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            4439..4948
                     /locus_tag="N8I87_RS35120"
                     /old_locus_tag="N8I87_35120"
     CDS             4439..4948
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018549486.1"
                     /locus_tag="N8I87_RS35120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35120"
                     /product="hypothetical protein"
                     /protein_id="WP_263214828.1"
                     /transl_table=11
                     /translation="MDDSTAAPGPRPHGTREAVLFGGVYGAVLASAMVAALTEYGHSSQ
                     AARRYDALWLLVTGLASALAHGYAHYVAERGPHRGWEFLRILADEWPLVAAMIPTVFIL
                     AGAGWGWWSASGVEYPAFVLNILILFVLGLVTAHWAARSWPVAVLIGAGDALLGVVVVV
                     ANALIH"
     gene            5016..6230
                     /locus_tag="N8I87_RS35125"
                     /old_locus_tag="N8I87_35125"
     CDS             5016..6230
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240770.1"
                     /locus_tag="N8I87_RS35125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35125"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_263214830.1"
                     /transl_table=11
                     /translation="MTRMAGMRVLSLCVAVLLAVMLQTTAVPAAERPGQGCVVGGQSTD
                     GRVRKVHDIVRQAQRELGLEAVLVRVTVDGHELVTDAAGESMTGVPATPALHFRAGSVA
                     IAHLGTVLLQLVDEHRVGLDDPVSRWLPDLPNGDRITLRMLGDSTSGLHDYVTDPAFVK
                     QFYADPFRHWTPSELPAFSLGHPLWYAPGTNWSYSHANFVLLGQALEKITGTPLDRLLR
                     KRVLDPLRLSQTANSFTPEIPRPVLHAYDAERGMYEESTFWNPSWTTAPGAVLSTDICD
                     LARSAQGIGSGRLLSRHSYQVQLDPGTPGLGTPTATCPATVCLKQTDAFHYGVGVIVKN
                     GWVVQNPSFAGFAAVQAYEPGERLAIAVSTTVGPKAPEGNTAQTITDRIAAALAPEHPL
                     GLDID"
     gene            complement(6233..6811)
                     /locus_tag="N8I87_RS35130"
                     /old_locus_tag="N8I87_35130"
     CDS             complement(6233..6811)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676283.1"
                     /locus_tag="N8I87_RS35130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35130"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_263214831.1"
                     /transl_table=11
                     /translation="MSAQPFPVSEIVASRRPHRKDAARNFDALLAAAREAFAEHGAEAS
                     LEDVARRAGVGIGTLYRNFPTRRDLFESVYADEVNALCRAAVQAAELPPWQALTTWLDR
                     FTGYMVTKRAVREALNDESEIFQACRDSMYSAGGPLLERAQKAGEARADMDFGDLVRMV
                     AGITATSFTDDAQRDRVLAIALDGVRVSR"
     gene            6999..8426
                     /locus_tag="N8I87_RS35135"
                     /old_locus_tag="N8I87_35135"
     CDS             6999..8426
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676284.1"
                     /locus_tag="N8I87_RS35135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35135"
                     /product="MFS transporter"
                     /protein_id="WP_263214833.1"
                     /transl_table=11
                     /translation="MPRNSTRLTFVVLATGAGVFAMLQSLIAPALPTVQHAMHSSQSTA
                     TWVMTAYLLSASVFTPILGRVGDLVGRKRTLVAVLMAVLAGCLVAALAPNMGVLIVARV
                     AQGVGGALFPLSFGIIRDEFAPARVSGSISNLSAVIAAGGGVGMVAAGPIVSALDYRWL
                     FWIPVAVVAATVPIALRYVPESPNRAEGSVSWLGAGLLSAWLVALLLPLSQAGQWGWGS
                     VKVLGLFAAAVVLFAGWLLVEARSRTPLIDLRVMRLPAVWTTNTAALLFGAGMYAIWSF
                     LPGFVQTPRSAGYGFGATVTESGLLMLPMLVAMFLSGVLGGRLAPVVGPKAQLTTGAAL
                     GAFALGFLALWHDERWQIAFVAGVFGLGIGLAFASMANLIVGSVPAEQTGAATGMNANI
                     RTIGGSVGAALTSVLVTGHLQPSGLPYGSGYAHGFTLLALLCLGAAGAALLVPVRRAGR
                     VTGPAAERAAAAPVRVR"
     tRNA            8470..8543
                     /anticodon=(pos:7705598..7705600,aa:Pro,seq:ggg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="N8I87_RS35140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="N8I87_35140"
                     /product="tRNA-Pro"
     gene            8470..8543
                     /locus_tag="N8I87_RS35140"
                     /old_locus_tag="N8I87_35140"
     gene            complement(8616..10004)
                     /locus_tag="N8I87_RS35145"
                     /old_locus_tag="N8I87_35145"
     CDS             complement(8616..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268956.1"
                     /locus_tag="N8I87_RS35145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35145"
                     /product="cytochrome P450"
                     /protein_id="WP_263214834.1"
                     /sec_met_domain="p450 (E-value: 7.9e-77, bitscore: 257.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATHEAPPVPRPTTTGVAPGGLPLLGHAIPLRRRPLDFLAALPA
                     YGDLVEVRLGPRRTYLACHPDLVQQVLRDSRTFDKGGPLFDKVRLLTGNGLATSSWADH
                     RRQRRLMQPAFRPERMAGYTPVMDHEIGSMLDSWEEGRAFDVNAAMQALTARIIVRTLF
                     STRIEDRAVAEIQRCLPVITRGFYTRMVAPVGLMEKLPTRSNRRFERALERMRGVIDET
                     IDAHRAGVDHGDLLSGLLDAEDEETGERLAGDEIHDQVMTLLLGATETTGNTLAWIFHL
                     LGENPEAEEQLHRELDGLRPGRRLGVDDLPHLDYTRRVIIESLRLYPTTWLLTRSTTCE
                     TELADVRLAPGTIVLLSFYALGRDPALYSAPERFDPDRWLPERAKAVPRGAWNSFGGGS
                     RKCIGDRFGTIEVMLVLAAVAADWRLRPRPGPGIRPEPKASLSTGPLPMIPERRRRGSP
                     AASE"
     gene            complement(10001..11167)
                     /locus_tag="N8I87_RS35150"
                     /old_locus_tag="N8I87_35150"
     CDS             complement(10001..11167)
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.2"
                     /locus_tag="N8I87_RS35150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35150"
                     /product="terpene synthase family protein"
                     /protein_id="WP_263214835.1"
                     /sec_met_domain="T1TS (E-value: 7.9e-55, bitscore: 185.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDISPLRTGTSLLARHEYEQPEGFFLPELPRLLPVVYHPKAAQI
                     EFRSNAWVRRHLAGCFADEEDLLKLLRERVGLYAPLIAPTADEQRVLDLADFYHFVGLI
                     DNLAADHTGLGASHLGARDVFDGIMADFAAGAATRAAAAASDNSPFGRAAQDLWRRISP
                     GLSPHQVRRFKSSMSSFLRGVTSELPYQLSGSVPDYDAYLAMRLDSFGCDFILLLTEYA
                     LAIDMTEPAASPRFVDMHAHAMRQLILVNDLLSLRKEQGDPMNAVRVLCCHDGLTLQRS
                     VDRVCDLVDLHERAYIAARDTVRHGPFGARADVRAYLDGLDHLLAGSQEYEYLTPRYFG
                     DGSVWDGSTSGWISLTTPIARFLPRTGHGNGATADQRARHPHRKERTS"
     gene            complement(11232..12260)
                     /locus_tag="N8I87_RS35155"
                     /old_locus_tag="N8I87_35155"
     CDS             complement(11232..12260)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349428.1"
                     /locus_tag="N8I87_RS35155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35155"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_263214837.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1e-44, bitscore:
                     151.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGSALADFLDQKCHTAESSRSLEPKETLRGFLSSGGKLIRPVMC
                     LCGWYAAGGAWDPGPVVKAAASLELFHAFALIHDDVMDDSDARRGRPALHRLLAEFHRH
                     RHTPGHAERHGVHAAVLLGDLALAWSDEMFHTAGLSPAQIRAARPLLDTMRGEVMFGQC
                     LDLLATGRPIGDIEHALTISRFKTAKYTVERPLHIGAALAGAGQAMLDTLTAYALPLGE
                     AFQLRDDLLGVFGDPRETGKPVDDDLREGKHTVLMAFGIARADHSQLSVLRSLVGRSDL
                     DAEQADAIRDVLVSTGARAAVEQMISSRRRRALSALHGAPLPPHAITALRRLAHAASAR
                     SS"
     misc_feature    complement(11295..11297)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12230..12244
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            complement(12618..15371)
                     /locus_tag="N8I87_RS35160"
                     /old_locus_tag="N8I87_35160"
     CDS             complement(12618..15371)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.3"
                     /locus_tag="N8I87_RS35160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35160"
                     /product="AAA family ATPase"
                     /protein_id="WP_263214838.1"
                     /transl_table=11
                     /translation="MLVGRTGTQQRGTRTGAGERRRRNSAITPSTLERDIELTVAQTSL
                     DALSSRSQTGATTPVARRDGVLAFTGAAGAGKTTLLDEVRRLAAERECRVLSAKGGELE
                     QGVAFHVVRQLFQPLLASYSDSERRELLGDWYAIIGPCIGLCPAGVGAAPDPQGVRDGL
                     DWLVTNVALRRGPLVMIVDDAHWVDLESLMWLTSFFRQAEDLPTLMVVAYRPEEPTEGA
                     KAFTGMMERNRVRPLDLEPLTAAAVSALLREALVKDVDEGFCQEAWRVTGGNPFETVEL
                     AARIREREVDPVRENVRLLRDLAAATTMGGGLVDRLEHLGTSATRLAWAVAILGSEATP
                     DLAASLAALGPANVAQTADLLRAEHILKPGERLEFAHPLIATKVYRAIPGETRAAMHGK
                     AAWELIDAGLGPAVAARHLLETQPEGDDAVARQLHDAAREYVRRGAPEAAHRCLSRALR
                     ETPVAELRAAILHELGSPAVTHDPVTAVNQLRAALDEPDLPPELRQAIVIRLARALAYC
                     DRLGEATSVMEEEARTTADARGRLRLLTEHFMLAAFTSEDHDGPALSRRLAQLTERLTG
                     REEIERYLFGLRGWDAVVRGEAVSTALQYAERAMSDEMSWTDERWGFEVPALVALTYLY
                     CDRPDRAEELFTRGISEFERQGWRGTPLALGYTFLGYIRFRCGRLTDAEDFVRAGLRLA
                     DRVSPDVPVHWYAIGSLIEILLARGQVDAAERMAADHGLGEPFPSAVTFPDAQTVHAEL
                     LLARGLAKEAAAELTRVGERLDGHGMRNPGLYPWLLRLALASHVTDVPRAQALAHTAVQ
                     RAERFGAASTTGHALRVMARLSDGPQAITLLQRAVTELERSPSTYELACALVELGTALR
                     RAGRVSQAAEPLYQGVDLATRCGADPMVTLARDELIAAGLRPRRLA"
     gene            complement(15589..16296)
                     /locus_tag="N8I87_RS35165"
                     /old_locus_tag="N8I87_35165"
     CDS             complement(15589..16296)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007495632.1"
                     /locus_tag="N8I87_RS35165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35165"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_263216810.1"
                     /transl_table=11
                     /translation="MTAQRSGAPSAAPELPRLGGRRSSYRERVAEALRAALIAGELRPG
                     EVYSAPSLAARFGVSATPVREAMLDLAKEGLVDTVPNKGFRVTAVSDKQLDEYTHIRSL
                     IEIPTVVELARTADRVCLEALRPAAREIVTAALAGDLITYVEADTRFHLGLLALAGNAH
                     LVEVVADLRGRSRLYGLTALVEAGRLLASAEEHLELLDALLDRDERAVREIMTRHLGHV
                     RGLWAARADREPG"
     misc_feature    16319..16329
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(16349..17350)
                     /locus_tag="N8I87_RS35170"
                     /old_locus_tag="N8I87_35170"
     CDS             complement(16349..17350)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358096.1"
                     /locus_tag="N8I87_RS35170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35170"
                     /product="proline racemase family protein"
                     /protein_id="WP_263214839.1"
                     /transl_table=11
                     /translation="MRSTLVLHAVDSHTEGMPTRVIIGGIGTVPGATMNERRLYFREHL
                     DHIKQLLMNEPRGHSAMSGAVLQPPTRPDCDWGVVYIEVSGYLPMCGHGTIGVATVLVE
                     TGMVEVVEPVTTIRLDTPAGLVVAEVAVEDGAARNVTLRNVPSFCAGLDRRAVLADGRT
                     VTYDLAYGGNFYAILPLEEFGLPFDRARKDDILRAGLALMDAINAEDEPVHPEDPSIRG
                     CHHVHLYAPGATARHSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGELPLHTEFVNES
                     FIGTRFTGRLLGETEVAGIPAVLPSFTGRAWITGTAQYLLDPTDPFPEGFVL"
     gene            complement(17366..18262)
                     /locus_tag="N8I87_RS35175"
                     /old_locus_tag="N8I87_35175"
     CDS             complement(17366..18262)
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069839.1"
                     /locus_tag="N8I87_RS35175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35175"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_263214840.1"
                     /transl_table=11
                     /translation="MTLPENRPWRGVLVATALPLRDDLTVDYDAYAEHCAWLLENGCDG
                     VVPNGSLGEYQVLTPEERARVVETAVAAIGGARVMPGVAAYGSAEARRWTEQAGEAGCA
                     SVMLLPPNAYRADERSVLAHYAEVAKAGLPVVAYNNPIDTKVDLVPELLARLHGEGHIH
                     GVKEFSGDVRRAYRLAELVPELDLLIGADDVLLELAVAGARGWVAGYPNALPAACAELY
                     RSAVSGDLAAALPLYRQLHPLLRWDSRVEFVQAIKLSMDIAGRHGGPVRPPRVPLLPEQ
                     EAAVRAATGKALAAGLG"
     misc_feature    complement(18287..18297)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 17.67"
                     /tool="antismash"
     gene            complement(18322..19727)
                     /locus_tag="N8I87_RS35180"
                     /old_locus_tag="N8I87_35180"
                     /pseudo=""
     CDS             complement(18322..19727)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020118954.1"
                     /locus_tag="N8I87_RS35180"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35180"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /pseudo=""
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.2e-26, bitscore:
                     90.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAERPRLAVIGAGPAGLAASLAAAARGVHVTLVDAAEEAGGQYYR
                     QPAAAFGARRAQALHHDRRTWKRLRTGLEHHITAGHLLHLADHHVWCVERESGADGFTV
                     HALRGPAQEEGVAVRADAVLLATGGYEKVLPFPGWTLPGVVTAGGAQAMLKGGLVLPGR
                     TAVLAGTGPLLLPVATGLAAAGARVAVLVESADPGALLRRPSALAAQPGKLAEGAWYAA
                     RLLRHRVRTLVRHTVVEAHGTDRLEAVTVAPLDAQGRTVPGAERRIQCDTLAVGHGMLP
                     HTDLAETLGCRLSDTNVRVDDEQRTDVPGVWAAGEATGIGGATLALAEGHIAGRSVAAR
                     LHGSRPTRAPGRPRPVPGPGCARSSRRSRRCTSRPRGGRSGSRTTLSCAAARRSPPGRS
                     GRP"
     gene            complement(<19786..20079)
                     /locus_tag="N8I87_RS35185"
                     /old_locus_tag="N8I87_35185"
                     /pseudo=""
     CDS             complement(<19786..20079)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484543.1"
                     /locus_tag="N8I87_RS35185"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35185"
                     /product="(2Fe-2S)-binding protein"
                     /pseudo=""
                     /sec_met_domain="Fer2_4 (E-value: 1.1e-28, bitscore: 98.1,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPLELAGARPGPAFTVTFDGRTIEALPGHTVAAALWAAGVTVWR
                     TTRSEGRARGVFCGIGVCFDCLVTVNGRPNQRACLVPVRPGDTIRTQEGAGHD"
     gene            complement(20076..21236)
                     /locus_tag="N8I87_RS35190"
                     /old_locus_tag="N8I87_35190"
     CDS             complement(20076..21236)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009323370.1"
                     /locus_tag="N8I87_RS35190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35190"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_263214842.1"
                     /sec_met_domain="DAO (E-value: 5.3e-66, bitscore: 222.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKRLTCDVVVVGAGMVGAACALYAARAGLDVMVVDRGPVAGGTT
                     GAGEGNLLVSDKEPGPELELALLSGRLWAELAQEKGDAIEYEPKGGVVVAETPESLSAL
                     ERFADGQRAAGVTAEAVGADRLHLLEPHLAPGLAGGVHYPQDAQVMPALAAAHLLRASG
                     ARLLTGRTVTAVPRTPGGAVRGVRTDHGEIHAPAVVNAAGTWGGELAGLAGVHLPVLPR
                     RGFVLVTEPLPRLVRHKVYAADYVADVASDSAALQTSPVVEGTAAGPVLIGASRERVGF
                     DRSFSLPAVRALAAGATRLFPFLARVRALRTYAGFRPYLPDHLPAIGPDPRVPGLFHAC
                     GHEGAGIGLATGTGHLIAQVLSGTAAELDLAPFRPERFPRDEVNTP"
     misc_feature    21242..21252
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 17.67"
                     /tool="antismash"
     gene            complement(21290..22096)
                     /locus_tag="N8I87_RS35195"
                     /old_locus_tag="N8I87_35195"
     CDS             complement(21290..22096)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133528.1"
                     /locus_tag="N8I87_RS35195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_35195"
                     /product="hypothetical protein"
                     /protein_id="WP_263214843.1"
                     /transl_table=11
                     /translation="MKRPYRPARVLASALAAGSLLATVSCSEDSGSPEAAPASPAAQRP
                     PSPSATRALTGPGAKAALITEADIEGDWTQVNNAATWRNELLVGKVDVAQFLSGKANAA
                     DCQKLLDGMYSDTLLGRATGASALTGFSAVDYRLLYQVGDYGKESVDKTLDWLKSLPQK
                     CAQFTATASDGSERTVQVVELPLPKAGDARQGLTVTVQGTADGQPVTLTQDVAVLRVGA
                     SGASVTNGGPSGADHPSTVSSVEAGALRLQDVLAGKTPTANPSQFD"
ORIGIN
        1 aggccgttga tccggatccg gtcccagcgg tgggcgtgcg ccgcgttgcg ggtcagaccg
       61 accagaccgg ccttggcggc gacgtacggg gccaggaagg gctgtccgcc gtgcgccgac
      121 gacgtgatga tgttgacgat cgtgccgggc gccttgcgct ccaccatgtc ggccaccgcc
      181 gcctgcatcg cgaagaacgg ggccttgagg ttgatcgcga tgtgcgcgtc gaacagctcg
      241 ggcgtggtgt ccagcagggt gccccgcgag gtcagccccg ccgagttgac cagacagtcg
      301 acccggccgt acgcgtcgac cacctcggcc acggagacct tggcccgccc ggcgtccgac
      361 aggtcggccc gcacgtacat cgccctgccc ccggccgccg tcagctcggc caccagggcc
      421 tcgcccggct cggggcgccg gccggtgacg gccaccgcgg cgccctcgcg gaccgaggcc
      481 cgggcgatgg cggcgccgac cccctggctg ccgccgttga cgaggacgac cttgtcgtcg
      541 agaagtccca tgacgtgctt gccccttcag ctctcgcgac gcggtcctgt cattcttgtc
      601 agtacaaacc cctccaacaa ccagcagcga gccatcaaaa acccctcaag gagcgccgcc
      661 gtgggccacc ccttcccgat ccgcgagatc gcacgtcagg caggtctcag cgaggccacc
      721 gtggaccgtg tgctgaacgg caggggaggg gtgcgggaga gcaccgccga ggaggtccga
      781 cgggccatcg ccgacctgga ccggcaacgc acccaggtac ggctggtcgg ccgtacgttc
      841 atggtcgaca tcgtgatgca ggcgccggag cggttcacca cggccgtacg cgccgccctg
      901 gaggcggagc tgccgtcgct gcacccggcc gtgctgcgct cccgcttcca cttccgggag
      961 accgggccgg tgcgggagct ggtggcgacc ctggaccggg tcacccggcg gggctcccag
     1021 ggcgtgatcc tcaaggcacc ggacgtcccc gaggtcacgg ccgccgtcgg ccgcctcgcc
     1081 accgcgggca tccccgtcgt gaccctggtg accgaccttc ccgcgagtgc ccggatggcg
     1141 tacgtcggca tcgacaaccg ggctgcgggc gcgacggcgg cgtacctcat ggggcagtgg
     1201 ctcggcgacc gtcccggcca tgtcctcacc agcctcagca gcggcttctt ccgcaacgag
     1261 gaggagcgcg agatgggctt ccgcggcgtc atgcgggccc ggcaccccca gcgcacgctc
     1321 gtcgagatcg ccgaggggca gggcctggac acgacccagt acgaccacgt ccgggccgcc
     1381 ctggaacgcg accccggcat acgggcggtc tactcgatcg gcggcggcaa catcgcgacg
     1441 ctacgggcct tcgaggacct gggccgcgag tgcgccgtgt tcgtcgccca cgacctcgac
     1501 cacgagaaca cccggctgct gcgcgaacac cgcctgtccg ccgtgctcca ccacgacctg
     1561 cgccacgacc tgcgcgaggc ctgccacctg gtgatgcgcg cccacggcgc actaccgccc
     1621 acgggaccgg tcgcaccgtc gtcgatccag gtggtcacgc cgtacaacat gcctacggcg
     1681 cctgcacgtt gacccatccg cccgtctccg cggaccgcgt catcgcgtcc agtacggcgg
     1741 cgctgtgcac ggcgtccacg agggtggtgc cgtacggtct gccctcggcg atcgagcgca
     1801 ggaaacggta cgcctcgatg accttcaggt cgtcgtagcc catggcgttg gccgcgcccg
     1861 gctggaacgc ggcgaactcg ccgtctccgg ggccgacgta caccgtgctg acgggctggt
     1921 cctggtacgt cgtgccgcgg ctgagagcca actcgttcat ccgccggaag tcccagaaga
     1981 ccgcgcccct ggtgccgtgc acctcgaagc cgtagttgtt ctgttcgccg accgagaccc
     2041 ggcaggcctc caggacaccg cgggcgccgg aggcgaaacg cagcaggcag ttgacgtagt
     2101 cctcgttctc gacggggccg agctcaccgc cggaggcacg ggcgtgcccg gcggtggcac
     2161 ccgtcgggcg ggcccgctcc ggcacgaaca ccgcggtgtc ggcggtcagc gcggcgatgt
     2221 cgccgagcag gaagcgggcc aggtcggcac cgtgcgaggc cagatctccg agcaccccgc
     2281 tgccgccgcg ctcacgctcg taccgccacg tcagggcgcc gtcgggatgg gccgcgtagt
     2341 cgctgaacag ccggatccgc acatgcgtca ccgcgccgat gtcccccgag gcgatcagct
     2401 cgcgggcggc ctgaacggcg ggcgcgttgc ggtagttgaa gccgaccgcg ccgtgcacac
     2461 cggccccggc caccgcgtcg gccaccgcgc gggcgtcctc cgcggtcagg cccaccggct
     2521 tctcgatcca gatgtgcttg ccgaccgcgg ccatcgcgac gccgatctcc cggtgcagaa
     2581 agttcggcgc ggtgatgctg accgcccgga cgcgcggatc cgcggccacc tcgcgccagt
     2641 cgcgggtcgt cgaggcgaac ccgaaccgcg ccgcggcctc ctcggcccgg cccggcacct
     2701 cctcggcgac cgtcaccagg cgcggccgca gggcgagccc ggggtagtgg tgcgcgacgc
     2761 gggcgtacgc ctgggtgtgc acccggccca tccagccgaa tccgacgacg gcgacaccga
     2821 gcgcatccac catgacagcc cctcgtacct cgttggaacc tgtttggacc ggtccattac
     2881 ttgtccaggc cacactggga ggcgaattcc gatgtgtcaa gccctttgac aaccgtgccc
     2941 accccatgga acggtccatg tcatgagacc gccgacgatc cgcgacgtgg ccgagcaggc
     3001 cggagtgtcc aagtcgctgg tctcgctggt gctgcgcggc tccgaccagg tgcgccccga
     3061 gaaacgggag gccgtgctgc gtgcggtacg ggagctcggc taccggccga acgcggccgc
     3121 gcgcagtctc agcgagcagc gcacccgcac cgtcggcgtc ctcctcaacg acctgcgcaa
     3181 cccatggttc gtcgacctcc tcgacggcct gaactcgctg ctgcgcgaca acggcctgca
     3241 catgctgctc gccgacgccc ggctgaaccg ccgcaccggc cacgacccca tcggcccgtt
     3301 cctggacctg ggcgtcgacg gcctggtggc ggtcggcacc ctgcccgaac cggccgttct
     3361 cggcgcggtc gccgagcgga tgccggtcgt cgtcgcgggc gcccgggagc ccgagctgcc
     3421 ggacgtggac gtcgtcgcgg gcgacgacga gaccggcgca cgcctcgtca ccgaacacct
     3481 catcgggctc ggccaccgcc ggatcgcgca catcgccggg tacggcgccg tcggcgagct
     3541 gcgccgacgc agcttcgagg cgacgatgcg ggcgcacggc ctggacgccg aggcgcggat
     3601 cgaggcgagc gacatgaccg aggagggcgg ctaccgcacc accatccggc tgctcagccg
     3661 cccggaccgg cccagcgcca tcctcgccgt caacgacatc gcctccgtcg gcgcgctgtc
     3721 ggcggccgag gaactggggc tgcgagtgcc gcgggacgtc tcggtgaccg gctacgacaa
     3781 cacgagcatc gcccggctgc gccacgtctg gctgaccacc gtcgacaccg ccccgcacga
     3841 ggtcggccgc cgcgccgccc gctgcctcct cgaccgcttc gagcggcccg ggggagcggg
     3901 ccgggtgcac ctcgccgcac cgacgctgga gatcaggggc accaccgcgg cgccccccgg
     3961 cctcacagat tgatcgcgta cgctttgcgc agcgtctcgt gcaccgtcca cgtcgtacgg
     4021 tcgccttcgc gcagtacggc catgtcgccc ggcccgacct ccagcgtcgg cccgcccccg
     4081 acctcgatcg tcgccgagcc gctgatgacg acgaacagct cgtccgcctc ggtgtcggtg
     4141 accacgcccg gggtgatctg ccagatcccg cggatccgcc ggccgtcctc cgactcccag
     4201 accacctttc cggtcacctc gggcgacccg gagacgatct gctccgggtc gaggggctcg
     4261 ggttcgagct cggcgtcggg gatgtggaga gcgaagctgt gcgtcatgag gcgaccctag
     4321 cgagctcacc ggcgctcgcg ccgtcgacag aatgtggggc atcgggcctg gtgggaggac
     4381 acttcgtcgg ggcgaagcaa agtggcggcg gcgccgggcg cgggtgatcg tgaggagcat
     4441 ggacgactcc acggcggccc ccgggccccg cccgcacggc acccgcgaag ccgtcctctt
     4501 cggtggggtc tacggcgccg tactggccag cgcgatggtc gccgcgctca ccgagtacgg
     4561 ccactcctcc caggccgccc gccgctacga cgccctctgg ctgctggtga ccgggctagc
     4621 ctccgccctc gcgcacggct acgcccacta cgtcgccgag cggggcccgc accgaggctg
     4681 ggagttcctg cgcatcctgg ccgacgagtg gccgctggtc gcggccatga tccccacggt
     4741 cttcatcctc gcgggggccg ggtggggctg gtggtccgcg agcggcgtcg agtacccggc
     4801 gttcgtcctg aacatcctca tcctgttcgt cctggggctg gtcaccgccc actgggcggc
     4861 acggagctgg cccgtggccg tgctgatcgg cgcgggggac gcgctgctcg gggtggtcgt
     4921 ggtggtggcg aacgcgctca ttcattagcc gggagtccgg ccgtcgcggc ggacgccggg
     4981 agcggcccgc accagggggt gccactatga ggcttatgac ccgaatggcg ggcatgcgcg
     5041 tgctctcgct gtgcgtcgcc gtcctgctcg cggtgatgct ccagacgacg gcggtaccgg
     5101 ccgccgagcg ccccggccag ggctgtgtcg tcggcgggca gagcacggac ggccgggttc
     5161 ggaaggtcca tgacatcgtg cggcaggccc agcgggagct cggtctcgag gccgtcctgg
     5221 tacgggtcac ggtggacgga cacgagctgg tcaccgacgc ggccggtgag tcgatgaccg
     5281 gcgtcccggc cacgcccgcg ctgcacttcc gggcgggctc ggtcgccatc gctcacctcg
     5341 gaaccgtgct cctccaactc gtcgacgagc accgggtggg cctcgacgac cccgtctccc
     5401 gctggctgcc cgacctgccg aacggcgacc ggatcacgct gcggatgctc ggcgactcca
     5461 cctccggcct gcacgactac gtcaccgacc cggcgttcgt gaagcagttc tacgccgacc
     5521 ccttccggca ctggaccccg agcgagctgc cggccttctc gctcggccat cccctgtggt
     5581 acgcgccggg caccaactgg agctactcgc acgccaactt cgtcctcctc ggccaggccc
     5641 tggagaagat caccggcact ccgctggacc ggctgctgcg caaacgcgtc ctcgatccgc
     5701 tgcggttgag ccagaccgcc aacagcttca ctccggagat cccgcggccc gtgctgcacg
     5761 cctacgacgc cgaacgcggc atgtacgagg agtccacgtt ctggaacccg tcctggacca
     5821 ccgcccccgg cgccgtcctc agcaccgaca tctgcgacct ggcgcgctcg gcccagggca
     5881 tcggatcggg tcggctgctc tcccggcact cctaccaggt gcagctcgac cccggcactc
     5941 ccgggctcgg caccccgacc gcgacctgcc ccgccaccgt gtgcctgaag cagaccgacg
     6001 ccttccacta cggcgtgggc gtcatcgtca agaacggctg ggtcgtgcag aacccctcct
     6061 tcgccggctt cgcggcggtg caggcctacg agcccggcga gcggctcgcc atcgccgtgt
     6121 ccaccaccgt gggccccaag gcgcccgagg gcaacacggc ccagacgatc accgaccgca
     6181 tcgccgcggc gctggccccg gagcacccgc tcggcctcga catcgactga gctcagcggc
     6241 tgacgcgtac gccgtccagc gcgatcgcca gcacgcggtc gcgctgggcg tcgtcggtga
     6301 aggaggtcgc cgtgatcccg gcgaccatcc gcaccaggtc gccgaagtcc atgtcggcgc
     6361 gtgcctcgcc cgccttctgc gcccgctcca gcagcggtcc gccggcggag tacatcgagt
     6421 cgcggcaggc ctggaagatc tccgactcgt cgttgagggc ctcgcgcacc gcccgcttgg
     6481 tgaccatgta gcccgtgaac cggtccagcc aggtggtcag cgcctgccac ggcggcagct
     6541 cggcggcctg tacggcggcc cggcacaggg cgttcacctc gtccgcgtag acgctctcga
     6601 agaggtcgcg gcgggtgggg aagttccggt acagcgtgcc gatgccgacg cccgcgcgcc
     6661 gggcgacgtc ctccagggag gcctccgcgc cgtgctccgc gaacgcctcg cgcgcggccg
     6721 cgagcagggc gtcgaagttg cgggcggcgt ccttacggtg cggccgccgg gacgcgacga
     6781 tctcgctgac ggggaacggc tgggccgaca ctgctgcctc ccgggacggg aatcgattga
     6841 aacggagggg tacctccgct atggtggagg ggtacctcca ctttagcagt ccgggggtgc
     6901 gccggccgtg cgcagaggtg tgtccgcggc gaccccggac gcccctcatt catttcattc
     6961 ctctcattcc tcgcgctccg attcggagag gctctgccgt gccccgaaac tccacccgcc
     7021 tcaccttcgt ggtcctcgcg accggtgcgg gcgtgttcgc catgctgcag tcgctgatcg
     7081 cgccggccct gccgaccgtc cagcacgcca tgcacagctc ccagtccacc gcgacctggg
     7141 tgatgacggc gtatctgctg tccgcctcgg tcttcacgcc gatcctcggc cgcgtcggcg
     7201 acctggtcgg ccgcaagcgc accctcgtcg ccgtcctcat ggccgtgctg gccggctgtc
     7261 tggtcgccgc gctcgcgccg aacatgggcg tcctgatcgt ggcccgggtc gcgcagggcg
     7321 tcggtggcgc cctgttcccg ctgtcgttcg gcatcatccg ggacgagttc gctcctgccc
     7381 gggtcagcgg cagcatcagc aacctgtccg ccgtgatcgc ggccggcggc ggtgtcggca
     7441 tggtggccgc cggtcccatc gtgtccgcgc tcgactaccg ctggctgttc tggatcccgg
     7501 tcgccgtcgt cgccgccact gtgccgatcg ccctccgcta tgtgcccgag tcgcccaacc
     7561 gggccgaggg aagcgtcagt tggctcggcg ccggactgct gtcggcctgg ctggtggcgc
     7621 tgctcctgcc gctcagccag gcggggcagt ggggctgggg atcggtgaag gtgctcgggc
     7681 tcttcgccgc cgccgtcgtg cttttcgccg ggtggctgct ggtcgaggcc cgctcccgca
     7741 ccccgctgat cgacctgcgc gtgatgcggc tgcccgccgt gtggaccacc aacaccgcgg
     7801 ccctgctgtt cggcgcgggc atgtacgcga tctggtcctt cctccccgga ttcgtgcaga
     7861 cgccccgctc ggccgggtac ggcttcggcg ccaccgtcac cgagtccgga ctgctcatgc
     7921 tgccgatgct cgtcgcgatg ttcctctccg gcgtcctcgg cggccgtctc gcccctgtcg
     7981 tgggtcccaa ggcgcagctc acgaccggtg ccgcgctcgg cgctttcgcc ctcggcttcc
     8041 tcgccctgtg gcacgacgag cggtggcaga tcgccttcgt cgcgggagtg ttcggcctcg
     8101 gcatcggact cgccttcgcc tcgatggcca acctcatcgt gggcagcgtc ccggccgagc
     8161 agaccggcgc cgcgaccgga atgaacgcca acatccgcac catcggcggc tccgtcggcg
     8221 ccgcgctgac cagtgtcctg gtcaccgggc accttcagcc ctccggcctg ccgtacggct
     8281 ccggctacgc ccatggcttc acgctgctcg cgctgctgtg cctcggtgcc gcgggcgccg
     8341 cgctcctcgt cccggtccgg cgcgccggcc gggtcaccgg ccccgccgcg gagcgagcgg
     8401 cggcagcacc cgtacgcgtg cggtagggtt gacctgcgcg atcacacgga acgccgtgtg
     8461 acatcgcacc gggacgtggc gcagcttggt agcgcacttg actgggggtc aaggggtcgc
     8521 aggttcaaat cctgtcgtcc cgacttgcga aggcgcagtt cagggcccgg accggagcaa
     8581 tccggtccgg gcccttcctt gttctgctcc gggttctact ccgaggcggc ggggcttcct
     8641 cggcgacgtc gctccgggat catggggagc gggccggtgc tcaggctcgc cttcggctcc
     8701 ggccggatgc cggggccggg ccggggcctc agccgccagt ccgcggcgac ggcggcgagg
     8761 accagcatga cctcgatcgt gccgaaccgg tcgccgatgc atttgcggct gccgccgccg
     8821 aaggagttcc aggcgccccg cggtacggcc ttggcccgct cgggcagcca gcggtcgggg
     8881 tcgaaccgct cgggggcgga gtacagggct gggtcacggc cgagggcgta gaagctgagc
     8941 agcacgatgg tgcccggggc gagccggacg tcggcgagtt ccgtctcgca cgtggtcgac
     9001 cgggtcagca accaggtggt cgggtacagg cgcagcgact cgatgatcac acgccgggtg
     9061 tagtccaggt ggggcagatc gtcgacgccg agccgacggc cgggacggag cccgtccagt
     9121 tcacggtgca actgctcctc cgcctccggg ttttcgccga ggaggtggaa gatccaggcc
     9181 agagtgttcc ccgtggtctc ggtcgcgccc aggagcaggg tcatgacctg gtcgtggatc
     9241 tcgtccccgg ccagtcgctc accggtctcc tcgtcctcgg cgtcgagcag gccggacagc
     9301 aggtccccgt gatcgactcc ggctcgatga gcgtcgatgg tctcgtcgat gacgccgcgc
     9361 atccgctcca gagcccgctc gaagcggcgg ttgctccggg tgggcagctt ctccatcagg
     9421 ccgaccggtg cgaccatgcg cgtgtagaaa ccccgggtga tgaccggcag acagcgctgt
     9481 atctcggcga cggcccggtc ctcgatgcgg gtggagaaca gcgtgcggac gatgatgcgc
     9541 gccgtgagcg cctgcatcgc ggcattgacg tcgaaggccc gcccttcctc ccacgagtcg
     9601 agcatggagc cgatctcgtg gtccatcacg ggggtgtacc cggccatcct ctcgggacgg
     9661 aacgccggtt gcatcagccg gcgttgccgc cggtggtccg cccaggagga cgtggccagg
     9721 ccgttgcccg tgaggaggcg gaccttgtcg aagagcgggc cgcccttgtc gaaggtccgt
     9781 gagtcacgca gtacctgctg gaccaggtcg ggatggcagg ccaggtacgt tcgtcgggga
     9841 ccgagccgta cctccaccag gtcgccgtac gcgggcagtg cggccaggaa gtccaacggc
     9901 cgtcgccgca ggggtatcgc atggccgagc agggggagcc caccgggagc cacgcccgtg
     9961 gtcgtggggc gcgggaccgg tggtgcctca tgggtcgccg tcaactcgtc cgctccttcc
    10021 ggtgtggatg ccgagcgcgc tggtccgctg tcgccccgtt tccgtggccg gtccggggca
    10081 ggaatcgggc gatgggagtg gtgaggctga tccacccgga ggtggagccg tcccacacgg
    10141 atccgtcgcc gaagtaacgc ggggtgaggt actcgtactc ctggctgccg gccagcagat
    10201 gatcaagtcc gtcgaggtag gcgcggacgt cggcgcgggc gccgaacggg ccgtgccgca
    10261 cggtgtcccg ggccgcgatg tacgcccgct catggaggtc gaccaagtcg cagaccctgt
    10321 cgacggaccg ctggagcgtc agcccgtcgt ggcagcacag cacccgtacc gcgttcatgg
    10381 ggtctccctg ctccttgcgc agggacagca gatcgttgac gaggatcagc tggcgcatcg
    10441 cgtgggcgtg catgtccacg aaccgaggcg acgcggccgg ctcggtcatg tcgatcgcga
    10501 gggcatattc ggtgagcagg aggatgaagt cgcagccgaa gctgtcgagc cgcatggcca
    10561 gataggcgtc gtagtccgga accgagccgg acagctggta gggaagctcg ctggtgactc
    10621 cccgcaggaa gctgctcatg ctcgacttga agcgccggac ctgatgtggg ctcagccctg
    10681 ggctgatgcg ccgccacaga tcctgagccg cccgcccgaa cggggagttg tcgctcgccg
    10741 cggccgctgc cctggttgcc gccccggcgg cgaagtcggc catgatcccg tcgaagacgt
    10801 cgcgggctcc gaggtggctg gctcccagcc cggtgtggtc cgccgccaga ttgtcgatga
    10861 gcccgacgaa atggtagaag tcggcaagat ccagcacgcg ttgttcgtcg gccgtcggag
    10921 cgatgagggg tgcgtacagg cccacgcgtt cgcgcaggag tttcagcagg tcctcctcgt
    10981 cggcgaagca ccctgccaga tgccggcgca cccaggcgtt cgaccggaac tcgatctgcg
    11041 ccgccttggg gtggtacacc accggaagga gccgcggcag ctccggaagg aagaatccct
    11101 cgggctgctc gtactcgtgc cgggcaagca gcgaggtgcc cgtgcgcagc ggtgagatgt
    11161 cagacatggg gtcccctgga gtcacgggag ttcatatcgg gcgagcgatg accacacttg
    11221 cgccgaggcg ctcaggaact gcgtgcggag gctgcgtgag ccagccggcg cagggccgtg
    11281 atggcatgcg ggggtaaggg cgctccgtgg agcgcgctca gggccctgcg ccgtctgctg
    11341 ctgatcatct gttccaccgc ggcgcgggca ccggtggaca ccagaacgtc gcggatcgcg
    11401 tcggcctgct ccgcatcgag gtccgaacgg cccaccagcg agcgcagcac gctcagttgc
    11461 gagtgatcgg cccgtgcgat gccgaaagcc atcagtacgg tgtgcttgcc ctcccgcagg
    11521 tcgtcgtcga cgggttttcc ggtctccctg gggtcgccga agacgccgag gaggtcgtct
    11581 cgcagctgga acgcctcgcc gagggggagg gcgtacgcgg tcagcgtgtc cagcatcgcc
    11641 tgaccggcgc ccgcgagcgc ggcaccgatg tgcagggggc gctcgaccgt gtatttggcg
    11701 gtcttgaagc ggctgatcgt cagggcgtgc tcgatgtcgc cgatcggccg tccggtggcc
    11761 agcagatcca ggcactggcc gaacatgacc tcgccgcgca tcgtgtcgag cagcgggcga
    11821 gccgctcgta tctgcgcggg tgagagacct gccgtgtgga acatctcgtc cgaccacgca
    11881 agagcgagat cgccgagcag tacggcggcg tggacgccat gccgttccgc gtgtccggga
    11941 gtgtgccggt gccggtggaa ttcggccagg agccggtgca gagccggccg cccccggcgg
    12001 gcgtcgctgt cgtccatgac atcgtcatgg atgagagcga aggcgtggaa cagctccaag
    12061 gacgctgcgg ccttcaccac gggccccgga tcccacgcgc cgcccgcggc ataccagccg
    12121 cacaggcaca tcaccggccg gatgagtttg ccgcccgagg aaaggaaacc gcggagcgtc
    12181 tccttgggtt cgagcgaccg ggaggactct gccgtgtgac atttttggtc gaggaaatcg
    12241 gccagggccg agcctgccat ctgccggatc cgcgcaaggt ccggcgccga gtgatcgaga
    12301 gttacgaccc gatcctccgt atccgtcgcc gctcgcatgg cccccccagg gatacgcccg
    12361 tcacagcgga gctccggagg aggctgctgc cacctgcgtc aaccgtgccg gatcgcgaaa
    12421 gaccttggtc ctccggggct cacgtggagc cttcacgggg aggccgtcgg cgaaacgtgt
    12481 atatggtccc catgtgcccc atggctcacg atctggcgcg cacgggggcg catttctggt
    12541 tcgggcgcgc cccatgaaat ccccatgcgc ccttggggtg aactccccat gcgtcctcga
    12601 cggccgctgt tcggcaccta tgccaggcgg cggggcctca gacccgcggc gatgagttcg
    12661 tcacgcgcga gggtcaccat gggatcggca ccgcaccgag tggccagatc caccccctgg
    12721 tacagcggct cggcggcctg cgaaacccgg ccggcccggc gcagtgccgt acccaactcg
    12781 accagggcgc aggcgagttc gtacgtcgag ggcgatcgct ccagttccgt gaccgcacgc
    12841 tgcagcaggg tgatggcctg gggcccgtcg ctcagtcgtg ccatgacgcg cagcgcatgc
    12901 ccggtggtgg aggccgcgcc gaagcgctcg gcacgctgta ccgctgtgtg cgccagtgcc
    12961 tgggcccgcg ggacatccgt gacgtgggat gcgagggcga ggcgcagcag ccatggatac
    13021 agccccggat tgcgcatccc gtgtccgtcc agccgttctc ccacccgggt cagttccgcc
    13081 gccgcttcct tcgccaaccc ccgggccagc agcagctcgg catggacggt ctgggcgtcg
    13141 ggaaacgtca cggcggacgg gaacggctca ccgagaccgt gatccgctgc catcctttcc
    13201 gccgcgtcga cctgcccccg ggcgagcagg atctcgatca ggcttccgat cgcgtaccag
    13261 tgcacgggca cgtcggggct cacccggtcg gccagccgca gtcccgccct gacgaaatcc
    13321 tccgcgtcgg tgagccggcc gcagcggaac cggatgtagc cgaggaaggt gtaaccgagc
    13381 gccaggggag taccacgcca gccctggcgc tcgaactccg agatgccgcg ggtgaacagc
    13441 tcctcggccc ggtcgggacg gtcgcagtac aggtaggtga gcgccaccag cgccggaacc
    13501 tcgaagcccc accgctcgtc cgtccagctc atctcgtcgc tcatggcccg ctcggcgtac
    13561 tgaagggccg tcgacaccgc ctcgccgcgc accacggcgt cccacccgcg cagcccgaac
    13621 agataccgct cgatctcctc gcgcccggtc agccgctcgg tgagctgggc gagccgacgt
    13681 gacagcgccg ggccgtcgtg gtcctcggag gtgaaggccg ccagcatgaa atgctcggtc
    13741 agcagccgca gccgaccccg tgcgtccgcg gtcgtgcggg cttcctcctc catgacgctc
    13801 gtcgcttcgc cgagccggtc gcagtacgcc agcgcccgcg cgagccggat cacgatggcc
    13861 tgacgcaact cgggcggcag gtcgggttcg tccaacgccg cccgcagctg gttgaccgcg
    13921 gtcaccgggt cgtgcgtcac cgccggcgaa ccgagctcgt gcaggatggc ggcccgcagc
    13981 tccgcgaccg gagtttcgcg caacgccctg ctcagacagc ggtgggcggc ctcgggagcg
    14041 ccccggcgca catactcgcg ggccgcgtcg tgcagttgtc gggccaccgc gtcgtcgccc
    14101 tcgggctgag tctccagcag gtggcgtgcc gccaccgccg gacccaggcc cgcgtcgatc
    14161 agttcccacg ccgctttgcc gtgcatggcc gcccgggtct cgccgggaat cgcccggtac
    14221 accttcgtgg cgatgagcgg atgcgcgaac tccagccgct cgccgggttt gaggatgtgc
    14281 tcggcccgca gcaggtccgc cgtctgcgcg acattggccg ggcccagtgc cgccagggac
    14341 gcggccagat ccggggtcgc ctccgaaccg agaatggcca ccgcccaggc gaggcgggtg
    14401 gcggacgtgc ccaggtgctc gagccggtcc accaggccgc cgcccatggt ggtggcggcc
    14461 gcaagatccc gcagcagccg gacgttctcc cggacgggat cgacctcccg ttcgcggatc
    14521 cgggcggcca gctccaccgt ctcgaaggga ttgccgccgg tgacccgcca cgcctcctgg
    14581 cagaacccct cgtcgacgtc cttgacgagc gcctcccgca gcagcgcgga gaccgccgcg
    14641 gccgtcaacg gctccaggtc cagcggccga acccggttcc gctccatcat gccggtgaac
    14701 gccttggcgc cctcggtcgg ttcctccggc cggtaggcga ccaccatcag cgtcggcaga
    14761 tcctcggcct gccggaagaa ggaggtcagc cacatcaggg actcgagatc cacccagtgc
    14821 gcatcatcga cgatcatgac caacggtcca cgccgcagcg ccacgttggt gaccagccag
    14881 tccaggccgt cccgcacgcc ctgcggatcg ggtgccgctc ctacccccgc ggggcacagg
    14941 ccgatacagg gcccgatgat cgcgtaccag tcgcccagca gttcgcgccg ctcactgtcg
    15001 gagtacgagg ccagcagcgg ctggaacagc tgccgcacca cgtggaaggc cacgccctgc
    15061 tccagctcgc cgcccttggc ggacagcacc cggcactcgc gctccgcggc gagcctgcgc
    15121 acctcgtcca gcagggtcgt cttgcccgcg cctgcggcgc cggtgaaggc cagcacaccg
    15181 tcccggcggg ccacgggggt ggtcgcgccg gtctgcgaac gactgctcag ggcgtccaac
    15241 gacgtctgcg cgacagtcag ttcgatgtct cgttccagag tgctcggggt gatcgcgctg
    15301 ttccggcggc gtcgctcgcc ggctcccgtc cgcgtcccgc gttgctgtgt cccggtccga
    15361 cccaccagca ctcgtccccc tcgcggcatg gcgccctccg tggcgcgccg ggaatcccac
    15421 cctgacacag cgtatccacc gatctacgtt cggcgagcag tcaatgtgca catacaccgc
    15481 gtgtgagtga gtggggctac actgtcgcct tctcgcccgt ttgtgaacgg tgggcgcgta
    15541 cttcgggtta cggcgaaccg ctggggagcg tcgtctccag gcggtcgctc agcccggttc
    15601 ccgatcggcc cgggcggccc acagaccccg tacatggcca agatgacggg tcatgatctc
    15661 gcgcacggcc cgctcgtcgc ggtccagcaa cgcgtccagg agttccaggt gttcctcggc
    15721 ggaggccagc agacgccccg cctccaccag cgcggtgagt ccgtagaggc gggagcgtcc
    15781 ccgtagatcg gcgaccacct cgacgagatg ggcgttgccg gccagggcga gcagccccag
    15841 gtggaagcgg gtgtccgcct cgacgtacgt gatgaggtcg cccgccagcg ccgcggtcac
    15901 gatctcccgg gcggccgggc gcagcgcctc cagacagacc cggtcggccg tcctggccag
    15961 ctccaccacg gtggggatct cgatgagcga gcggatgtgg gtgtactcgt cgagctgctt
    16021 gtcggagacg gcggtgaccc ggaacccctt gttggggacc gtgtcgacca gtccctcctt
    16081 ggccaggtcc agcatcgcct cgcgcaccgg ggtcgccgag acaccgaagc gggcggccag
    16141 cgagggggcc gagtagacct cgccgggccg cagctcaccg gcgatcagcg cggcccgcag
    16201 ggcctcggcg acccgctcac ggtagctgct ccgacggccg cccaggcggg ggagttcggg
    16261 tgcggcagac ggggcgccgc tgcgctgggc ggtcatcggg ttctcctcga acgactggtg
    16321 ccatgtcatg tgttgccagt atggagggct agagcacaaa gccctccggg aaggggtccg
    16381 tgggatcgag cagatactgg gccgtgcccg tgatccaggc gcggccggtg aagctcggca
    16441 gcacggccgg gatcccggcg acctcggtct cgcccagcag ccgtccggtg aaccgcgtgc
    16501 cgatgaagga ctcgttcacg aactcggtgt gcaggggcag ttcgccgcgc gcgtgcagtt
    16561 gtgccatgcg cgcgctggta cccgtaccgc agggcgagcg gtcgaaccag ccggggtgga
    16621 tggccatcgc atgccgcgag tgacgggcgg tggcgccggg tgcgtacaga tggacgtgat
    16681 ggcagccgcg gatggagggg tcctcggggt ggaccggctc gtcctcggcg ttgatggcgt
    16741 ccatcagggc cagacccgcc cttaggatgt cgtccttgcg ggcgcggtcg aagggcagcc
    16801 cgaactcctc cagcggcagg atcgcgtaga agttcccgcc gtacgcgagg tcgtacgtca
    16861 ccgtccgccc gtcggcgagc accgccctgc ggtccaggcc ggcgcagaac gacggcacgt
    16921 tccgcagcgt gacgttcctg gcggcgccgt cctcgaccgc gacctcggcg acgacgagtc
    16981 cggccggggt gtcgaggcgg atggtggtga ccggctcgac gacctccacc atgccggtct
    17041 ccaccagcac ggtcgccacg ccgatcgtgc cgtgcccgca catcggcaga tagccggaga
    17101 cctcgatgta gacgacaccc cagtcgcagt cggggcgggt cggtggctgc aggaccgcac
    17161 cgctcatcgc cgagtgcccg cgcggctcgt tcatcagcaa ctgcttgatg tggtcgaggt
    17221 gttcacggaa gtacagtcgc cgctcgttca tcgtcgcacc ggggacggtg ccgatcccgc
    17281 cgatgatcac gcgggtgggc atgccctcgg tgtgcgagtc gacggcgtgc aggacgagtg
    17341 tgctgcgcac gttcgggcct ccttgtcagc cgaggcccgc ggcgagggcc ttgccggtcg
    17401 ccgcgcggac ggcggcctcc tgctcgggca gcagcgggac ccgcggcggg cgtaccgggc
    17461 cgccgtgccg tccggcgatg tccatggaca gcttgatggc ctggacgaac tcgacccgcg
    17521 agtcccagcg cagcagcgga tgcagctgcc ggtacagggg aagcgcggcg gcgaggtccc
    17581 ccgacacggc ggaccggtac aactcggcgc acgcggcggg cagcgcgttc gggtaaccgg
    17641 ccacccagcc cctggcgccc gcgacggcga gttccagcag tacgtcgtcg gcaccgatca
    17701 acagatcgag ttccgggacg agttcggcga gccggtaggc gcggcgcacg tcgcccgaga
    17761 actccttgac cccgtggatg tggccctcgc cgtgcagccg cgcgagcagt tcggggacga
    17821 ggtcgacctt ggtgtcgatc gggttgttgt acgccaccac cggcaggccc gccttcgcga
    17881 cctcggcgta gtgggcgagc acggaccgct cgtcggcgcg gtaggcgttg ggcggcagca
    17941 gcatcaccga cgcacagccc gcctcgcccg cctgctcggt ccagcggcgg gcctcggcgg
    18001 atccgtaggc ggcgacgccc ggcatcaccc gcgcgccgcc gatcgcggcc acggccgtct
    18061 cgacgaccct ggcgcgctcc tcgggggtga gcacctggta ctcaccgagc gagccgttgg
    18121 gcacgacgcc gtcgcagccg ttctccagca gccaggcgca gtgttcggcg tacgcgtcgt
    18181 agtcgacggt gaggtcgtcg cgcaggggga gcgcggtggc gaccaggaca ccgcgccagg
    18241 ggcggttctc cgggagggtc atgagtggtc cccaatccga tggtgtgtga catagtactg
    18301 attccggaca gctgtcggca gtcagtccga cctgagctcc tcgtcctgcc cggcgagcac
    18361 ccccaggggc accggccggg cgagcggtcg ccgcgccggg gtgagcgggc acccggtgag
    18421 cccggcgacc gccggcccgc acatccgacc ctggcaccag cccatcccgg cccgggtgag
    18481 cagcttcacg gtgcgcagat cacctgcgcc gagaccgctc acggacgccc ggatctcccc
    18541 ggcggtgacc tcctcgcagc ggcacacgac agtgtcgtcc gtgacccgct ccgcccaccc
    18601 cgcgggcggc tcgtacaccg tctcgagcgc cgcgaagaac gcgcgcagcc gggtccgggc
    18661 acgggccgcg gccgcccagg cgcgcgggtc ggccggctcc cgtggagacg ggcggcgacg
    18721 gaacggccgg cgatgtggcc ctcggccagg gcgagcgtcg ccccgccgat cccggtggcc
    18781 tccccggccg cccagacgcc gggcacatcg gtgcgctgct cgtcgtccac ccggacgttc
    18841 gtgtcggaga gccggcagcc cagcgtctcg gccaggtcgg tgtgcggcag catgccgtgc
    18901 ccgacggcga gagtgtcgca ctggatgcgg cgctcggcgc cgggcacggt ccgcccctgt
    18961 gcgtcgagcg gcgcgacggt caccgcttcc aggcggtccg tgccgtgcgc ctcgaccacg
    19021 gtgtgccgga cgagcgtgcg cacccggtga cgcagcagcc gggccgcgta ccaggcgccc
    19081 tccgcgagct tgccgggctg cgcggccagg gcggacggcc ggcgcaggag tgccccggga
    19141 tccgcggact cgacgagcac ggccacgcgc gcgcccgccg ccgcgagccc cgtcgccacg
    19201 ggcagcagca gcggcccggt cccggcgagc acggcggtgc gtcccggcag caccagcccg
    19261 cccttgagca tggcctgcgc cccgcccgcg gtgacgaccc cgggcagggt ccagcccggg
    19321 aagggcagca ccttctcgta accgccggtg gcgagcagga cggcgtcggc gcgcaccgcg
    19381 acgccctcct cctgggcggg accccgcagc gcgtgcacgg tgaacccgtc ggcccccgac
    19441 tcccgctcca cgcaccacac atgatgatcc gccaggtgga ggagatgtcc ggccgtgatg
    19501 tggtgctcga gcccggtgcg cagccgcttc caggtccgcc ggtcgtggtg gagggcctgc
    19561 gcgcggcgcg cgccgaacgc ggcggcgggc tgccggtagt actgcccgcc cgcctcctcg
    19621 gcggcgtcga cgagggtgac gtgcaccccg cgcgcggccg ccgccagcga cgcggcgagg
    19681 cccgccgggc ccgccccgat cacggcgaga cgcggtcgct cagccatcgt gatccgtccc
    19741 ttcccgggta cggccgtcgt cgcccgtccc ttccgcggta cggccgtcgt ggccggcccc
    19801 ttcctgtgta cggatcgtgt cgcccggcct taccggaacc aggcaggccc gctggttcgg
    19861 gcggccgttg acggtcacca ggcagtcgaa gcacaccccg atcccgcaga agaccccgcg
    19921 cgcccggccc tcgctccggg tggtgcgcca tacggtcacg cccgccgccc acagcgcggc
    19981 ggcgaccgta tggccgggca gcgcctcgat cgtccggccg tcgaacgtca ccgtgaacgc
    20041 cggacccggt cgcgctccgg ccaactccag ggggttcatg gggtgttcac ctcgtctcgc
    20101 gggaatcgct ccggcctgaa cggcgcgagg tccagctccg ccgccgtgcc gctcagcacc
    20161 tgggcgatca agtgcccggt gccggtggcg agtccgatgc ccgcgccctc gtgcccgcag
    20221 gcgtggaaca gtccgggtac ccgggggtcg gggccgatgg cgggcagatg gtcgggcagg
    20281 tacggtcgga aacccgcgta cgtgcgcagc gcgcgcaccc gggccaggaa cgggaacagc
    20341 cgggtcgccc cggccgccag cgctcgtacg gcgggcaggg agaacgaccg gtcgaagccg
    20401 acccgttcgc ggctcgcgcc gatcaggacc ggtccggcgg ccgtgccctc gacgaccggt
    20461 gaggtctgca gcgcggccga gtcgctggcg acgtccgcca cgtagtcggc cgcgtacacc
    20521 ttgtgccgga ccagccgggg cagcggctcg gtgaccagga cgaagccgcg ccgggggagt
    20581 accggcaggt gcacgcccgc cagacctgcc agctcaccgc cccaggttcc cgcggcgttc
    20641 accacggccg gcgcgtggat ctcgccgtgg tccgtgcgga ccccgcgcac cgcgccgccc
    20701 ggtgtgcgcg gcaccgcggt cacggtccgg ccggtgagga ggcgggcgcc cgaggcacgc
    20761 agcaggtggg cggcggccag cgccggcatc acctgggcgt cctgcggata gtgcacaccg
    20821 cccgcgaggc cgggtgccag atggggttcg agcaggtgga gccggtcggc gcccaccgcc
    20881 tccgccgtga ctccggccgc ccgctgcccg tccgcgaacc tctccagggc ggagaggctt
    20941 tcgggtgtct cggcgaccac gacgccgccc ttgggctcgt actcgatcgc gtcgcccttc
    21001 tcctgcgcca gctcggccca caagcggccg gacagcagcg cgagttccag ctccgggccg
    21061 ggctccttgt cggagacgag cagattgccc tcaccggcgc cggtggtgcc gccggcgacg
    21121 ggaccgcggt ccaccaccat cacgtcgaga ccggcccgtg cggcgtacag cgcgcaggcc
    21181 gcgcccacca ttccggcacc gaccaccacg acatcgcagg tcagtcgctt ccccacgcca
    21241 gtactatgtc acatgtcgct gcgcctgggg agggtcgcgc cggagagggt cagtcgaact
    21301 ggctcgggtt cgcggtcggg gtcttcccgg cgagcacgtc ctgcagtcgc agggcgcccg
    21361 cctccacgga cgacacggtg ctggggtgat cggcgcccga cggaccgccg ttggtgacgg
    21421 aggccccgga ggcgccgacc cggagcacgg cgacgtcctg ggtgagcgtg accggctgac
    21481 cgtccgcggt gccctgcacc gtcaccgtca gcccctgtct ggcgtcgccc gccttgggca
    21541 gcgggagttc gacgacctgt acggtccgct cgctgccgtc ggaggcggtc gccgtgaact
    21601 gggcgcactt ctgcggaagg ctcttgagcc agtcgagggt cttgtccacc gactccttgc
    21661 cgtagtcgcc gacctggtag agcagccggt agtccaccgc gctgaagccg gtcagcgccg
    21721 acgcgccggt cgcccgcccc agcagcgtgt cggagtacat cccgtcgagg agcttctggc
    21781 agtcggcggc attggccttc ccgctgagga actgggcgac gtcgaccttg ccgacgagca
    21841 gttcgttgcg ccaggtcgcc gcgttgttga cctgcgtcca gtcgccctcg atatcagcct
    21901 ccgtgatcag cgcggccttg gccccgggcc cggtcagggc gcgcgtggcg gacggcgacg
    21961 ggggccgctg ggccgcgggc gaggcgggtg cggcctccgg ggacccgctg tcctccgagc
    22021 aggagaccgt ggccaggagc gaccccgcgg ccagggccga ggcgagaaca cgtgcgggac
    22081 ggtacggacg cttcatcgcg gcggcctcca gtggaacgcg gtacgtcctt ccacgccacc
    22141 accgctcccg gcggccgacc agcgcaccgg gccgttcggg tgaagcggtc cgcgggcgcc
    22201 cggacctgct cacgtgcgca gcccttcgcg gatgctcggc cttccgcggg tgctcagccc
//
