LOCUS       NZ_CP106798            22214 bp    DNA     linear   CON 01-NOV-2023
DEFINITION  Streptomyces sp. HUAS 15-9 chromosome, complete genome.
ACCESSION   NZ_CP106798
VERSION     NZ_CP106798.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. HUAS 15-9
  ORGANISM  Streptomyces sp. HUAS 15-9
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9258818)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 169.8x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/01/2023 03:42:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,774
            CDSs (total)                      :: 8,679
            Genes (coding)                    :: 8,175
            CDSs (with protein)               :: 8,175
            Genes (RNA)                       :: 95
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 504
            CDSs (without protein)            :: 504
            Pseudo Genes (ambiguous residues) :: 0 of 504
            Pseudo Genes (frameshifted)       :: 260 of 504
            Pseudo Genes (incomplete)         :: 328 of 504
            Pseudo Genes (internal stop)      :: 29 of 504
            Pseudo Genes (multiple problems)  :: 107 of 504
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:51:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6917707
            Orig. end                         :: 6939921
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP106798.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo Ping.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22214
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="19"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22214
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22214
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12214](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12214
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(491..504)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    complement(867..885)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.09"
                     /tool="antismash"
     gene            1394..2128
                     /locus_tag="N8I87_RS31560"
                     /old_locus_tag="N8I87_31560"
     CDS             1394..2128
                     /EC_number="3.4.13.21"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016805 - dipeptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971705.1"
                     /locus_tag="N8I87_RS31560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31560"
                     /product="peptidase E"
                     /protein_id="WP_263213801.1"
                     /transl_table=11
                     /translation="MPASEPTILATSGGHRVGGRTMVEFDALVHHAVDLSGVHGRPPRV
                     MYVGTAIGDAEHFTARMSEAARVAGFDLTPLHLFPMPNLDDVEGAVLAQDVVWVMGGSV
                     ANLLAVRRVHGLDRIMRRAWEPGVVLSGVSAGSLCWFRGGTTDSFGPELRPLTDALGFL
                     PYGNGVHYDTDRGRRPLVHRLVADGTLPTTHCTDDGVGLVYRGTELSEAVTEIPGKGAY
                     VVLRDGDTVVEERLEPRLLPGV"
     gene            complement(2145..2603)
                     /locus_tag="N8I87_RS31565"
                     /old_locus_tag="N8I87_31565"
     CDS             complement(2145..2603)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062785.1"
                     /locus_tag="N8I87_RS31565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31565"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_263213802.1"
                     /transl_table=11
                     /translation="MTGRSPQGMRPAFRRWRARRPFWGGLLLTLGGAEVLLTMKASMKV
                     VMHVGMQGLAGYLLPTVMLLCGLLTLFSPAQRIFYSLIGVLASLATWLTSNLGGFFIGL
                     LLGLIGSSLTFGWLPDQEPRVSRRRRRREQEAARATAPALAEDTAEPA"
     gene            complement(2603..3265)
                     /locus_tag="N8I87_RS31570"
                     /old_locus_tag="N8I87_31570"
     CDS             complement(2603..3265)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547163.1"
                     /locus_tag="N8I87_RS31570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31570"
                     /product="DUF6230 family protein"
                     /protein_id="WP_263216753.1"
                     /transl_table=11
                     /translation="MASSADNIPENPESGSRDITEGIDRRGRVRLRRAAVLAVPATLAV
                     AGLAVLTAEGALGVQFAISGMPFTVTATNLDGTGFEQFGNLDNMAEGSPNTGDTGGQVL
                     VVTSAIKNATLTKLCQSVDLGGINLKITAGGGKDKVTATDLTTDSTELSGEASFDNIEI
                     GNDASTLTKAGVKGPIGVFSQQADTVHIGNLRQTNYATTAGVFKLPGLKLGFSDSAC"
     misc_feature    complement(3439..3453)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.94"
                     /tool="antismash"
     misc_feature    3441..3454
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.6"
                     /tool="antismash"
     misc_feature    complement(3445..3460)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.38"
                     /tool="antismash"
     gene            3871..4521
                     /locus_tag="N8I87_RS31575"
                     /old_locus_tag="N8I87_31575"
     CDS             3871..4521
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675693.1"
                     /locus_tag="N8I87_RS31575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31575"
                     /product="Tat pathway signal sequence domain protein"
                     /protein_id="WP_263213804.1"
                     /transl_table=11
                     /translation="MRTRSLLALAGTVVALTAAATVPASADGAVLTTGSAGGTAVAVGD
                     VLSAPLASGTSATLYSSATGTSGVTCTSSTFTATVTDNPAAPGTATEAVDAQTFDSRSC
                     TSNVLGVTGVTSITVDNLPYTTSVASDGTLTVTPASGSTIQTTVKLKTLLGSITCVYQA
                     ASLTGKADNADNSIAFTNQQFTKSSGSSLCFASGFFTAKYAPVTDAGAAVYVN"
     gene            complement(4540..5484)
                     /locus_tag="N8I87_RS31580"
                     /old_locus_tag="N8I87_31580"
     CDS             complement(4540..5484)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122074.1"
                     /locus_tag="N8I87_RS31580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31580"
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_263213806.1"
                     /transl_table=11
                     /translation="MTRMTAHLRVTGAAVAASALLSLWAAEPALAHGAPTDPVSRVYAC
                     SPSGGSASTAACRAAIAANGTSFVAWDNLRVAGVDGRDRQLIPDGKLCSGGLPAYKGLD
                     LARADWPSTRLAPGARLTMTYASTIAHTGTFKLYLTKPGYDPAGPLKWSDLPARPFAQV
                     TDPALTNGAYHFTAKLPSDRTGRQVLYTIWQNSSTSDTYYSCSDVVISKAAKASDEAGG
                     AGGPAKKQESSGPSRSAEPSRSTSSKSAATPSTPVAAAPQSASAEGTTTDSTPVASDTA
                     TGSGPSAPLIAGGAAAVLVLTGGAALVLRLRRR"
     misc_feature    5821..5836
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.33"
                     /tool="antismash"
     misc_feature    complement(5894..5903)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.63"
                     /tool="antismash"
     gene            5949..6596
                     /locus_tag="N8I87_RS31585"
                     /old_locus_tag="N8I87_31585"
     CDS             5949..6596
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657051.1"
                     /locus_tag="N8I87_RS31585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31585"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_263213807.1"
                     /transl_table=11
                     /translation="MARQLRAEQTRATIITAAADLFDRQGYESTSLSDIVEHAQVTKGA
                     LYFHFAAKEDLAYAIMELQSRASRQVLREVESRTCSSLEALMRTTFGIARLAVEGPIPR
                     AGLRLATAEVAVRPPLRHPFAEWLELATRKLLGAVRESDVHPDIDIDAVAHSLVYFFVG
                     TRVAGRSLEPVARLPRRVAEMWHLMIRGLVPVPRRARYLTLASQLEREIRTV"
     misc_feature    5961..5963
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6619..7824
                     /locus_tag="N8I87_RS31590"
                     /old_locus_tag="N8I87_31590"
     CDS             6619..7824
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675697.1"
                     /locus_tag="N8I87_RS31590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31590"
                     /product="damage-control phosphatase ARMT1 family protein"
                     /protein_id="WP_263213808.1"
                     /transl_table=11
                     /translation="MPDTSAAPVILGNEPGSFPLGVLAERHPAIIRQVRDAFPYDPEQH
                     RALDALHKSCTEGVIEPLPADAPDRDRWREWGMDAYTGRSWFDVPWLWSESYFYRRLLD
                     AVGFFGPGAWRGIDPFRPFKLAELDARETDEELAALDALEDGPAHERAPALLHGSLWGN
                     RADLGFRLSDAGAEAKEAVPALVADDSETLWSLLPPSGTGTLCLVADNAGRELVPDLLL
                     IARLLAEGRIGRAVLHVKPYPYYVSDATTADVVDALRRLVSAPGAAAAYGRRLWAAMAD
                     GRLAVRAHPFTCAPLPYTDMPDDLRAEFAAATLTLFKGDLNYRRMVGDRLWPPTTPFRD
                     VTAYFPGPVAALRTLKSDVITGLDARTEAALVAAEGQRWRTGGTHALIQVDPLNPRTAE
                     AT"
     misc_feature    complement(6668..6683)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            complement(7796..9058)
                     /locus_tag="N8I87_RS31595"
                     /old_locus_tag="N8I87_31595"
     CDS             complement(7796..9058)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015493378.1"
                     /locus_tag="N8I87_RS31595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31595"
                     /product="cytochrome P450"
                     /protein_id="WP_263213810.1"
                     /sec_met_domain="p450 (E-value: 2.4e-19, bitscore: 68.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVRQAPPVPDVFDPRRYALGVPYDDYRVLRDHHPVARQEEPEVL
                     GWPAGPGFWAVTRHADVVRVLKDAATYSSYIGATQIRDPDPEDLPFLRSMMLNQDPPQH
                     GRLRRLVSRAFTRARVDRFADVTRERARTLLAGAVAAARASDGTVDLVTAVTDEYALLN
                     LADLLGVPKGDRRLLLRWTQRVIGYQDPDEAGPPVLDGEGKPVNPRSPAMLRDMFDYAR
                     QLAAYKRRYPADDVMTTLAHDAELTGAELEMFFFLLTVAGNDTVRSAAPGGLLALVEHP
                     EAYRSLRDGQVHLPTAVDELLRWHPPVLTFRRTAAHDTELAGRKIRAGDKVVVFHASAN
                     RDERAFTGPDRLDPARTPNPHVSFGDGPHVCLGAHFARLQLRLLYEEALRVLPAPRLAG
                     PAERLVSNFINGLKSLPLYVD"
     gene            complement(9055..9846)
                     /locus_tag="N8I87_RS31600"
                     /old_locus_tag="N8I87_31600"
     CDS             complement(9055..9846)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-239). E-value:
                     1.1e-25. Score: 82.6. Matches aSDomain:
                     nrpspksdomains_N8I87_RS31600_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645379.1"
                     /locus_tag="N8I87_RS31600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31600"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_263213811.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.1e-19, bitscore:
                     70.8, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 4.5e-19, bitscore: 68.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSFVLPHEMHGDGAHKVFAVHGWFADRSAYAAVLPDLDRETFTY
                     ALVDLRGYGRAKDAVGAYTTVEAALDLVELADRLGWERFSVVGHSMGGAVAQRLLAVAP
                     HRLRRIVGVSPVPASGLPLPGEQWELFADAAHRPENRRAIIDFTTGGRRPAAWLDRMVD
                     TSLERSDAKAFRAWLDSWAGDDFRADVEGSDVPALAVAGELDPALSPELVQETWMSCYP
                     RAELRRLPSAGHCAMDETPLELIRVVEDFLREDGPGKDGTA"
     aSDomain        complement(9130..9786)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_N8I87_RS31600_Abhydrolase_1.1"
                     /evalue="1.10E-25"
                     /label="N8I87_RS31600_Abhydrolase_1.1"
                     /locus_tag="N8I87_RS31600"
                     /protein_end="239"
                     /protein_start="20"
                     /score="82.6"
                     /tool="antismash"
                     /translation="VHGWFADRSAYAAVLPDLDRETFTYALVDLRGYGRAKDAVGAYTT
                     VEAALDLVELADRLGWERFSVVGHSMGGAVAQRLLAVAPHRLRRIVGVSPVPASGLPLP
                     GEQWELFADAAHRPENRRAIIDFTTGGRRPAAWLDRMVDTSLERSDAKAFRAWLDSWAG
                     DDFRADVEGSDVPALAVAGELDPALSPELVQETWMSCYPRAELRRLPSAGHCAMDE"
     CDS_motif       complement(9556..9591)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_N8I87_RS31600_0001"
                     /evalue="2.90E-04"
                     /label="NRPS-te1"
                     /locus_tag="N8I87_RS31600"
                     /protein_end="97"
                     /protein_start="85"
                     /score="13.4"
                     /tool="antismash"
                     /translation="VVGHSMGGAVAQ"
     gene            10001..12214
                     /locus_tag="N8I87_RS31605"
                     /old_locus_tag="N8I87_31605"
     CDS             10001..12214
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019981792.1"
                     /locus_tag="N8I87_RS31605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31605"
                     /product="terpene synthase family protein"
                     /protein_id="WP_263213812.1"
                     /sec_met_domain="T1TS (E-value: 1.5e-78, bitscore: 264.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFELPHFYMPYPARLNPHVDEARAHSTVWACEMGMLEGSGVW
                     AQADLEAHDYGLLCAYTHPDCDGPALSLITDWYVWVFFFDDHFLERYKRTQDRAAGKAH
                     LDRLPLFMPLDLATAVPEPENPVEAGLADLWARTVPSMSADWRRRFALATEHLLNESMW
                     ELSNIDEGRIANPVEYIEMRRKVGGAPWSAGLVEYASAEVPARVAGSRPLRVLMETFSD
                     AVHLRNDLFSYQREVEDEGENSNGVLVLETFFGCTTQEAADTVNDILTSRLHQFEHTAL
                     TEVPALALDKGLTPDQVAAVAAYTKGLQDWQSGGHEWHLRSSRYMNEGAVSVSPRHGLT
                     GPGTSAADIGALLASAAAERLRAYSHVPFQKVGPSLLPDFRMPFPLALSEHLDGARERL
                     AGWMHWTGMLREGVWDEDKLTAYDLALCSAGLDPDATPEALDLSAQWLAWGAYGDDYYP
                     LVFGHRRDLAAARLTTRRLSACMPLDGEAVPAPANGMERGLCDLWARTTAEMPPGERTA
                     LKQSVDAMTESWVWELSNQLQNRIPDPVDYLEMRRATFGSDLTLSLCRRGRGPAIPPEV
                     YRSGPVRSLENAAMDYGCLLNDVFSYQKEIEYEGEIHNGVLVVQNFFGVDYPTALGVVH
                     DLMTQRMRQFEHVAANELPVMYDDFDLPEETREAVRGYVLDLQNWLAGVLHWHQRVDRY
                     RAPYLARRAHGFLPDARPASPLLGGFQTLSCGVGHSGNVGGPS"
     gene            12269..14152
                     /locus_tag="N8I87_RS31610"
                     /old_locus_tag="N8I87_31610"
     CDS             12269..14152
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360990.1"
                     /locus_tag="N8I87_RS31610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31610"
                     /product="multicopper oxidase domain-containing protein"
                     /protein_id="WP_263213813.1"
                     /transl_table=11
                     /translation="MTEIIERITEAVDGGQPSAPPELTPYVAPLPVPSVLRPASADVTH
                     ETEIALRPTWIRLHPQLPPTLMWGYDGQVPGPTIEVRRGQRVRIAWTNRIPKDSEYPVA
                     SVEVPLRTDGRPQATTEPGREGVEPDKDVAALPAWTVTHLHGAQTGGGNDGWADNAVGH
                     GDAQLSEYPNDHQAVQWWYHDHAMNITRWNVHTGLYGTYLVRDDEEDALHLPRGEREIP
                     LLLADRNLDTDEDGRLNGRLLHKTVIVQQRNPETGKPVSIPFTGPYTTVNGRIWPYADV
                     DAAWYRFRLVNASNARIYDLVLVDEDDNPVPGVVHQIGSDGGLLPRPVPIDFDDTLPTL
                     TAAPAERFDLLVDFRGLAGKRFRLVDKGRNRPAGVPDPAGDVRYPAVLEFRVQDCESTD
                     TFELPEVLSGSFRRLTHDVPHGHRLIVLTPPATKGAGGHPEIWEMTQVEDAGDIQVPTD
                     GIIRLTGADGTTKTYRRTSRTFNDGLGFTIAEGSYEQWSFLNLAPIVHPMHIHLADFQL
                     LGRDAYDVSGFDPAVGGTVEPVAFDPGTQLPLAPNERGHKDVFRVPGGQILRVMGRFDG
                     AYGRFMYHCHLLEHEDMGMMRPFVVMPPEALKFDHGAAHGGHGEQHTGHTG"
     gene            14320..14895
                     /locus_tag="N8I87_RS31615"
                     /old_locus_tag="N8I87_31615"
     CDS             14320..14895
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657043.1"
                     /locus_tag="N8I87_RS31615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31615"
                     /product="PDZ domain-containing protein"
                     /protein_id="WP_263213814.1"
                     /transl_table=11
                     /translation="MEETALRPKPMPGQERRDCGTPGTPGTITGTPGAGQRPHAARRRG
                     RRLRTLLLSLFVGTVLVLSGVGLGTVGASVIGMSRLAQLRHQAPPPAAAATRSAAPSPV
                     GVSLGVEAVDAEKSGALVVGVHEPGPAHIAGLVVGDVLLRFGGTRLGTAADLARAVSRA
                     RPGAEVTLTVRHRGGGYQRLTAVPGVVT"
     gene            15029..16156
                     /locus_tag="N8I87_RS31620"
                     /old_locus_tag="N8I87_31620"
     CDS             15029..16156
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996926.1"
                     /locus_tag="N8I87_RS31620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31620"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_263213815.1"
                     /transl_table=11
                     /translation="MTGSMPAPFTADDYRARMERAARCAAEAGLAGLLVAPGPDMVWLT
                     GYAPTAVTERLTVLVLAAGRDPVLVVPTLEAPDAEKAAGASALTLRGWTDGTDPYAVTA
                     ALLDAGGRFGISDNAWAMHLLGLQKILPGTSYAALTDALPMLRAVKDAAELELLASAGA
                     AADAAFEEIRKVSFAGRRESDVGRDLADLLRRFGHSQVDFTIVGSGPNGANPHHEVGDR
                     VIRDGDMVVLDFGGLKDGYGSDTSRTVHVGEPTDEERKVHDIVRAAQEAGFRAVRPGVA
                     CQEVDRAARAVIAGAGYGEYFIHRTGHGIGVTTHEPPYMIEGEAQPLVPGMCFSVEPGI
                     YLPGRFGVRIEDIVTVTADGGRRLNNTTRDMVIVD"
     gene            16227..17171
                     /locus_tag="N8I87_RS31625"
                     /old_locus_tag="N8I87_31625"
     CDS             16227..17171
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996925.1"
                     /locus_tag="N8I87_RS31625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31625"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_263213817.1"
                     /sec_met_domain="APH (E-value: 1.9e-19, bitscore: 69.5,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPTPTADTVRRLVSTLLKESADSTSGPDVRPVAEGGEHSTWW
                     VGTRHVLRLAPDRDAAARQRRELRLRDLVRPHVPVTVPLSVAHGEWAPGLTYTLDTKVP
                     GGTGEEHDVSAVGEADLSGLLTALRQVPVRQAETLGVPRVAPRSLEALRRMAVRAAERL
                     GAADEFDPALILQLTPAGAAQLAAQPGTAVLVHHNLRGEHLVVSADGRVRGILDWTGVV
                     VGDPAEDIAGLALAVGSGAAVRAATLAGYGARPCLRGLWLARCDTVVRLMNRLDGHDTG
                     PLPLLRTQLRRAWEAILLERVTDFRDEETREEL"
     gene            complement(17182..18927)
                     /gene="treZ"
                     /locus_tag="N8I87_RS31630"
                     /old_locus_tag="N8I87_31630"
     CDS             complement(17182..18927)
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431956.1"
                     /locus_tag="N8I87_RS31630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31630"
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_263213819.1"
                     /sec_met_domain="CBM_48 (E-value: 4.3e-05, bitscore: 22.6,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 4.4e-11, bitscore:
                     41.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFEVWAPQADRVTLHCDGATRALERNPERAGWWTGQSPAQDGTR
                     YGFALDDGPVLPDPCSRHQPDGPDGPSAVVDQERYAWRAEWAGRPLPGAVLYELHVGTY
                     TREGTLDAAAERLGHLVELGVTHVELMPLCPFPGRHGWGYEGVSLWAVHEPYGGPEALK
                     RFVDRAHELGLGVVLDVVHNHLGPSGNHLPAFGPYFTETHHTPWGAAVNLDAPGSDEVR
                     AYLVGSALAWLRDYRIDGLRLDAVHALRDTRAYPFLEELSAAVDGLCSELGRPLFLIAE
                     SDVNDPRLITPRAEHGLGLHAQWNDDFHHALHTALTGESQGYYADFARAPFVALAKTLS
                     GGFFHDGTYSGFRGRHHGRPLDRATVAGHRLLGYSQTHDQIGNRAQGDRLSQSLSPGLL
                     ACAAALTLTAPFTPMLFMGEEWAAGTPWQFFTDHTDPELAQAVRQGRRREFAAHGWAEE
                     DVPDPQDPATRERSCLDWSEPEREPHARVLAWYRRLVALRREEADLTDPDLADTKVAYD
                     EQARWLAFRRGDVRVAVNLGKEPAAIPLGAGEVRVLAAWDPVEAPGADGLLLVPGESCV
                     VLTQG"
     gene            19102..19653
                     /locus_tag="N8I87_RS31635"
                     /old_locus_tag="N8I87_31635"
     CDS             19102..19653
                     /GO_function="GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385491.1"
                     /locus_tag="N8I87_RS31635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31635"
                     /product="DUF1707 and FHA domain-containing protein"
                     /protein_id="WP_263213821.1"
                     /transl_table=11
                     /translation="MTSSFEFNTYPARLSDAERDKALQVLRDGVAMGRLSHDTFVRRME
                     LALAARRADELAVLTADLPRENRLSRVLFGTVEAVSGFTVRLRTAWQAERLPKLMLPHA
                     GNGHPLRIGRDPANGLRLNHETVSRVHAELRRQGGMWVLRDLGSTNGTTVNGRRVIGAA
                     VVRDGDQVGFGRMAFRLSLN"
     gene            19815..21140
                     /locus_tag="N8I87_RS31640"
                     /old_locus_tag="N8I87_31640"
     CDS             19815..21140
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062765.1"
                     /locus_tag="N8I87_RS31640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31640"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_263213822.1"
                     /transl_table=11
                     /translation="MDELGARAAALVARRPEDARLRRIGTSRAGAPLWLLSIGHGSRHA
                     LVVAGPHANEPVGGATALRLAERTLADSRLTEAADTTWNLLLCLDPDGSRRNEGWLSGP
                     YTLDHYFRNFFRPGFLEQPEWLPEGAAAAVLPETRALLQLQDELRPFLQCSLHGVDVGG
                     GFVELTRDLPGLARRVAHSAARLGIPRELGAYDTLYWPSVGPAVYRIPPPRRGDLAAAI
                     TEAAVESTWFHPHRYGTVTAIVEAPMWGVAAVEDGSPPADRDAVLRTVSGTLRHDTRLL
                     DDVLARIRPQLAAVPDVGSLLAPVDDYLLVCPGLADSWDPDTDDGSARPLPALNTAHLA
                     ALRISGRRLALRTAGLLRRLVLSTGHDPAGVLPDLDRLIDAWCADYRDGCGARWIPVAR
                     QAEYQARVVLSAFELARQHARVPSRSGESGWGAGAAVPMHRE"
     misc_feature    20739..20741
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21137..21562
                     /locus_tag="N8I87_RS31645"
                     /old_locus_tag="N8I87_31645"
     CDS             21137..21562
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125307.1"
                     /locus_tag="N8I87_RS31645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_31645"
                     /product="subtilase-type protease inhibitor"
                     /protein_id="WP_263213823.1"
                     /transl_table=11
                     /translation="MTYFKQATAVRGALLAAAALVAACPAPAAQAAARDAHSGNWLYLT
                     VTRGDTRSGDMRGTLLLCDPPLGHAHAAEACAELEAADGDIGSLRANADAVCPMIYAPV
                     TVRVFGQWHGRTVQNEKTFSNSCAMEAGTGEVFRLDD"
ORIGIN
        1 gtgtgcctgc gccgccaggc cggggccgta ctcgacgacc gtggtggcgt ggtcctgggt
       61 ggtggccgtc gcggtgccgg tgaccgtgaa accgtctgcg gtgaggtcgg cggcgccccg
      121 ggcggccagg ccgggcacgg cggtgccgtt gtagacggcg acgtcgatgc cggaaccgga
      181 gaccggggcg gcggaggggg aaggggaggg ctggggggcc ttcttaccgt cggcgttctt
      241 gccgtcgatc gtgcggtcgg ccttgagcgc ggcccacagc gcgttcgcgt cgggctccac
      301 gacggcgacg cgtgacccct cgtaccgcca ggggatggtc acgaacttgg tgttgtgcag
      361 gtctatgtcc ttcagcgaca tcgcgaagga gatgagcttg tcggcggtgc cgagcccggt
      421 gtccaccgtc agcgacctgg tcgcggcgtc ggccagcggc agcagcttgg tgggggtcag
      481 ccccttgctc ttgacctcct tcaacaggct tgccacgaag gcctgctggc gtttgatacg
      541 gccgatgtcg gagccgtcgc cgatcccgtg ccggatgcgc acatagtcca gggcccgctg
      601 cccggagacg gtctgctcgc ccttcttgaa cagcagctct ccgcgggtgg tgcggtgggg
      661 gttgaggtcg ttctcgtaca cgtcgcccgg cacgcacacc ttgacgccgc ccaccacctc
      721 ggtcagggcc gcgaaaccct tgaagtcgac gacgacggtg tggtcgaccc gcagtccggt
      781 cagcttctcg acggtgttct gggtgcaggc ggggttgccc ttgtcggtct cgcccacgga
      841 gaaggccgcg ttgaacatcg tgtcggcctg ggtcttcgtc cagctgccgt cggggagttc
      901 gcacggcggg acggtgacca gggtgtcgcg ggggatggag accgcgaggg cgtgcttgtg
      961 gtcggcgtat atgtgcagca ggaaggtcgt gtcggagcgg cctatgtcgt ccttgttgcc
     1021 gccgcccagg gccgcgttgc cgtcggtgcg cccgtcggag ccgatgacca ggacgttctc
     1081 acccttggac gagcccgccg cgggacggtt gtcggagagg ccgcccgagt cgaacgtgtt
     1141 gatgttcccg ttcagcttca gatacagcca gccggccccg cccgcgacga gcacgagcag
     1201 ggacaggcag acggcgagcg cggtccgtat ccggccgccg gggcggcgcc gccgttccct
     1261 ggcgctcctg ctggcgatgg tcatcgacgc cctctcacgg tctccacccc gggttgtaca
     1321 agctgcgcaa tgtagcaacc gtcggtgagg gggaaacgta agaaagaaag aggagggcgc
     1381 cggcatccgc accgtgcctg cctccgaacc caccatcctc gccacctccg gcggacaccg
     1441 cgtgggcggc cggaccatgg tcgagttcga cgcgctggtc catcacgcgg tggacctctc
     1501 gggcgtccac ggccgtccgc cgcgggtcat gtacgtcggt acggcgatag gcgacgccga
     1561 gcacttcacc gcccgtatgt cggaggcggc gcgggtggcg gggttcgatc tgaccccgct
     1621 ccacctcttc ccgatgccca acctggacga cgtcgagggc gcggtcctcg cgcaggacgt
     1681 cgtgtgggtc atgggcggtt cggtggccaa tctgctggcc gtgcggcggg tgcacggcct
     1741 ggaccggatc atgcgccggg cctgggagcc gggtgtcgtg ctcagcgggg tcagcgccgg
     1801 gtccctctgc tggttccggg gcggcaccac cgactccttc ggccccgaac tccgcccgct
     1861 caccgacgcg ctcggcttcc tgccgtacgg caacggcgtt cactacgaca ccgacagggg
     1921 ccgccgcccc ctggtccacc ggctggtggc cgacggcacc ctgcccacca cgcactgcac
     1981 ggacgacggc gtcggcctgg tctaccgggg cacggagctc tccgaggcgg tcaccgagat
     2041 cccgggcaag ggcgcgtacg tcgtcctgcg ggacggcgac accgtggtgg aggaacgcct
     2101 cgaaccccgg ctgctgccgg gggtgtgaga cgggcgccgc gggctcacgc cggttcggcc
     2161 gtgtcctccg cgagggcggg cgccgtcgcc cgggccgcct cctgctcgcg tcggcggcgg
     2221 cgtcggctca cccggggctc ctggtccggc agccagccga aggtgaggct gctgccgatg
     2281 aggccgagca ggaggccgat gaagaagccg ccgaggttgg aggtgagcca ggtggccagg
     2341 gaggccagga caccgatgag ggagtagaag atccgctggg ccgggctgaa cagggtcagc
     2401 aggccgcaca gcagcatcac ggtcggcagc agatagcccg ccaggccctg catgccgaca
     2461 tgcatgacga ccttcatcga cgccttcatg gtgagcagga cctccgcccc gcccagggtg
     2521 agcaacagcc cgccccagaa cggacggcgg gcccgccagc gccggaaggc gggccgcatc
     2581 ccctgcggtg accggccggt catcagcagg ccgagtcgct gaagccgagt ttcagccccg
     2641 gcagcttgaa cacgccggcg gtggtggcgt agttggtctg ccgcaggttg ccgatgtgca
     2701 cggtgtcggc ctgctggctg aagacaccga tcgggccctt caccccggcc ttggtcagcg
     2761 tgctggcgtc gttgccgatc tcgatgttgt cgaacgaggc ctcgcccgac agctcggtgg
     2821 agtcggtggt caggtccgtc gccgtcacct tgtccttgcc gccgcccgcg gtgatcttca
     2881 gattgatgcc accgaggtcg acgctctggc acagcttggt gagcgtggcg ttcttgatcg
     2941 cggaggtgac caccagcacc tgaccgcccg tgtcacccgt gttcgggctt ccctcggcca
     3001 tgttgtcgag gttgccgaac tgctcgaagc cggtgccgtc gagattggtc gccgtgaccg
     3061 tgaacggcat gccggagatg gcgaactgga cacccagcgc gccctccgcg gtgagcaccg
     3121 cgaggcccgc gacggccagc gtggccggca cggccagcac ggcggcgcgg cgcagccgga
     3181 cccggccgcg tctgtcaata ccttcggtga tgtcccggga accgctttcc gggttctcgg
     3241 ggatgttgtc ggcggacgag gccatctctg ctcccatggg caaaatcaac gcgggttggg
     3301 cttcagcggc acgatgtcct ggcgcggaca gcggctgtcg cgcacgactc ctcacaactc
     3361 ccggcgattg caagggcttt ctcattacgc gtcagtagcc gacgaggaag ttaccggggg
     3421 ttacttttcg cggtcaagag agttgtgaaa aaagagtgtt gaatgtgggt cagttgtgct
     3481 ctgaccttga actcccttga ccggccttga cgttgacgga ctctcaggtc tacaactctt
     3541 cctggtttcc cttggatccg tggcgccgga tccgccgccg cggcatcgcc cgcgtcccgg
     3601 cccgaacccc ccaccccctt caccgctccg catcagcgcg gcaacggtca cggtcccttc
     3661 cctcctcggt ccgtgcccgg ccgcccctta cccggcccgg ccggaggcct ctccccccga
     3721 agtctccggc cggtgtccgg ccggctgccg ttgccggtcc gtcacgtacg gagaaggcgt
     3781 aacgggtcgg caacggcttt cgccgcacgc gcccccactc accccccacc tcacctcacg
     3841 cagcccccca cccaaggaaa gaggctcccc atgcgtacgc gatccctcct cgccctcgcc
     3901 ggaaccgtcg tagccctcac ggccgcggcc accgtccccg cctccgcgga cggcgccgtg
     3961 ctcaccacgg gcagcgccgg cggcaccgcc gtggcggtcg gcgatgtgct cagcgcgccg
     4021 ctggccagcg gcaccagcgc gacgctctac tccagcgcga ccggcaccag cggagtgacc
     4081 tgcacgtcct cgacgttcac ggccaccgtc accgacaacc ccgccgcccc cggcacggcc
     4141 accgaggcgg tcgacgcgca gaccttcgac agccgcagct gcaccagcaa cgtcctcggt
     4201 gtcaccggcg tcaccagcat cacggtcgac aacctgccgt acaccacctc ggtcgcctcc
     4261 gacggcaccc tcaccgtcac cccggcgagc ggctccacca tccagaccac ggtcaagctg
     4321 aagaccctgc tgggcagcat cacctgcgtc taccaggcgg ccagtctgac cggcaaggcc
     4381 gacaacgccg acaacagcat cgccttcacc aaccagcagt tcaccaagag ctccggctcc
     4441 tcgctctgct tcgccagcgg cttcttcacc gcgaagtacg cccccgtcac cgacgcgggc
     4501 gcggccgtct acgtgaactg acgcaccgaa ccccggcgtt cagcgccggc gcagtctcag
     4561 cacgagggcg gcgcccccgg tgagcaccag caccgcggcg gcgccgcccg caatcagcgg
     4621 cgcggacgga cccgagccgg tcgcggtgtc ggaggcgacc ggcgtgctgt cggtggtggt
     4681 gccctcggcc gaggccgact gcggggcggc cgccaccggg gtcgacgggg tcgcggcgct
     4741 cttcgaggac gtcgaacggc tcggctccgc gctcctcgac ggaccggagc tctcctgctt
     4801 cttcgccgga ccgcccgccc cgcccgcctc gtccgacgcc ttggcggcct tggagatcac
     4861 cacgtcggaa cacgagtagt aggtgtccga cgtgctgctg ttctgccaga tggtgtagag
     4921 cacctgacgg cccgtccggt ccgacggcag cttcgcggtg aagtggtacg ccccgttggt
     4981 cagggccggg tcggtgacct gggcgaaggg ccgcgcgggc aggtcggacc acttcagcgg
     5041 cccggccgga tcgtagccgg gcttggtcag atacagcttg aacgttcccg tgtgcgcgat
     5101 cgtcgaggcg tacgtcatcg tcagccgcgc gcccggggcc agccgcgtcg acggccagtc
     5161 cgcgcgggcc aggtcgaggc ccttgtaggc gggcagtcct ccgctgcaca gcttgccgtc
     5221 cggaatcagc tgccggtccc ggccgtcgac tcccgccacc cgcaggttgt cccacgccac
     5281 gaaggacgtg ccgttcgcgg cgatcgccgc ccggcaggcc gccgtcgagg cgctgccgcc
     5341 gctgggggag caggcgtaca cccggctgac cggatccgtc ggcgcgccgt gcgccagggc
     5401 gggctccgcc gcccacaaag agagcagggc cgaggccgcg acggcggccc ccgtgaccct
     5461 gaggtgtgcg gtcatccgag tcatccggga cgtctcctcg gccggcgctg gaacggtctg
     5521 ttccgtgcag tacggaaacg acccccgtcc cgttcacatc acggcccaca tcacggccgc
     5581 acagtacggc cggtcctcgc gaaagcgacc aagagtcaac gaccgaccgg tccgtctgtt
     5641 ttgaggtccc gtcgagggcc cattgagaac gggccgcccg cctcgtatcg tggcgatcac
     5701 cggtgtgatg gcccgtcggc cgccaaagcc tccggaaata cgggagacgt cgagggaggg
     5761 acgtactttg acttcgtccg tttgtggggg atcgatggtg gcgacggtcg tccacacatc
     5821 agttacacgt gtcgaccact cgccccgaac acccgactcc cgttctctca gggtgagcta
     5881 tcgtatgcga ggggtaaaaa acaaacggca cgtcccgttc gtttctgacc gcaaggagtg
     5941 tccagtcgat ggcgaggcag ttacgcgccg agcagacccg agcaacgatc atcacagccg
     6001 cagccgacct gttcgaccgt cagggctacg aatccaccag tctgagtgac atcgtcgaac
     6061 acgcccaggt caccaagggg gcgctgtact tccacttcgc cgccaaggag gatctggcgt
     6121 acgccatcat ggagctccag tccagggcgt cgcggcaggt gctgagagaa gtggagagcc
     6181 ggacctgctc ctcgctggag gccctgatgc gcaccacgtt cgggatcgcc cggctcgccg
     6241 tcgagggccc catcccccgg gcggggctcc gcctggccac cgcggaggtc gccgtacggc
     6301 cgccgctgcg gcatcccttc gccgagtggc tggagctggc cacccgcaaa ctcctcggag
     6361 ccgtcaggga gtccgatgtg cacccggaca tagacatcga tgccgtcgct cactcactcg
     6421 tgtatttctt cgtcggcacc cgggtcgcgg gccgctccct cgagcccgtc gcccgactgc
     6481 cgcgcagagt cgccgagatg tggcacctca tgatccgcgg cctggtcccg gtgccccggc
     6541 gcgcccgcta tctgaccctc gcctcgcagc tggagcggga gatcagaacc gtctgacgcg
     6601 cgcgatacgg tgacgcgcat gcccgacacc tccgccgcgc ccgtgatcct cggcaacgaa
     6661 cccggttcgt tccccctcgg cgtgctggcc gaacggcacc ccgccatcat ccggcaggtg
     6721 cgggacgcct ttccgtacga ccccgagcag caccgcgcgc tcgacgcgct gcacaagagc
     6781 tgcaccgagg gcgtgatcga gccgctcccc gccgacgcgc ccgaccggga ccgatggcgg
     6841 gagtggggca tggacgcgta caccggccgg tcctggttcg acgtcccctg gctgtggtcc
     6901 gagagctatt tctaccgccg gctcctcgac gcggtcggtt tcttcgggcc cggcgcctgg
     6961 cggggcatcg accccttccg ccccttcaaa ctggccgaac tcgacgccag ggagacggac
     7021 gaggaactgg ccgcgctgga cgcgctggag gacggcccgg cccacgagcg ggcgccggcc
     7081 ctgctgcacg gctcgctctg gggcaaccgc gccgacctcg gcttccggct gtccgacgcc
     7141 ggtgccgagg ccaaggaggc cgtgcccgcc ctggtcgccg acgacagcga gaccctgtgg
     7201 tccctgctgc cgccctccgg cacgggcacc ctgtgcctgg tcgcggacaa cgcgggccgc
     7261 gaactcgtcc cggacctgct gctgatcgcc cgcctgctcg ccgaggggcg tatcgggcgg
     7321 gccgtgctgc acgtcaagcc gtacccgtac tacgtctccg acgccacgac cgccgacgtg
     7381 gtcgacgccc tgcgccggct cgtctcggcg ccgggcgcgg cggccgcgta cgggcggcgt
     7441 ctgtgggcgg ccatggccga cggccgactg gccgtacgcg cccacccctt cacctgcgcc
     7501 ccgctgccgt acacggacat gcccgacgac ctccgcgcgg agttcgccgc ggccacgctg
     7561 acgctcttca agggcgacct caactaccgg cgcatggtgg gcgaccggct gtggcccccg
     7621 accacgccct tccgggacgt caccgcctac ttccccggcc cggtcgccgc cctgcgcacg
     7681 ctcaagtccg atgtgatcac cggcctggac gcccgcacgg aggccgccct ggtcgctgcc
     7741 gagggacagc gctggcggac cggtggcacg cacgcactga ttcaggtcga tccactcaat
     7801 ccacgtacag cggaagcgac ttgagcccgt tgatgaagtt ggacaccaga cgctcggcgg
     7861 gtccggccag gcgtggtgcg ggaagcaccc gtagcgcctc ctcgtacagc agccgcagct
     7921 gaagccgcgc gaagtgggca cccagacaca catgcggacc gtccccgaag gacacatgcg
     7981 gattgggcgt acgggccggg tccagacggt ccggaccggt gaaggcccgc tcgtcccggt
     8041 tggccgaggc gtggaagacg accaccttgt caccggcccg gatcttccgc ccggccagtt
     8101 cggtgtcgtg tgccgcggta cggcggaagg tcagcacggg cggatgccag cgcagcaact
     8161 catcgacagc ggtggggaga tggacctgcc cgtcgcgcag cgaccggtac gcctccggat
     8221 gctctaccag cgccagcagc ccgcccggag cggcgctgcg caccgtgtcg ttgcccgcga
     8281 cggtgagcag gaagaagaac atctccagtt ccgctccggt gagttcggcg tcgtgtgcga
     8341 gtgtggtcat cacgtcgtcg gcggggtagc gccgtttgta cgccgccagc tgccgggcgt
     8401 agtcgaacat gtcccgcagc atcgcgggcg accgcggatt gaccggcttg ccttccccgt
     8461 cgagcaccgg gggaccggcc tcgtccgggt cctgatagcc gatcacccgc tgtgtccagc
     8521 gcagcagcag cctccggtcg cccttcggga cacccagcag gtcggcgagg ttgagcagcg
     8581 cgtactcgtc ggtgacggcc gtgaccaggt cgaccgtgcc gtccgacgcg cgggccgccg
     8641 ccacggcgcc ggcgagcagc gtgcgggccc gctcccgcgt gacgtccgcg aaccggtcga
     8701 cccgcgcgcg cgtgaacgca cggctcacca gccgcctcag ccgcccgtgc tgcggcgggt
     8761 cctggttgag catcatgctc cggaggaacg gcagatcctc cgggtctgga tcccggatct
     8821 gggtcgcccc gatgtacgac gaatacgtcg ccgcgtcctt cagcacccgc accacgtccg
     8881 cgtgccgggt caccgcccag aaaccgggcc cggccggcca gcccagcacc tcgggctcct
     8941 cctgccgggc cacggggtgg tggtcgcgca ggacgcggta gtcgtcgtac ggcacaccca
     9001 acgcgtagcg gcgcggatcg aagacgtccg gaacgggtgg agcctggcgc acgctcacgc
     9061 cgtgccgtcc ttgccgggcc cgtcctcgcg caggaagtcc tcgaccaccc ggatcagctc
     9121 cagcggggtc tcgtccatcg cacagtgtcc ggcgctcggc aggcgccgta gctccgcgcg
     9181 cgggtagcag gacatccagg tctcctggac cagctcgggt gacagggccg ggtcgagctc
     9241 tccggccacg gcgagcgcgg gtacgtccga gccctcgacg tcggcgcgga agtcgtcgcc
     9301 cgcccatgag tccagccagg cacggaacgc cttggcgtcg ctgcgctcca gcgaggtgtc
     9361 gaccatccgg tccagccagg ccgcgggacg gcggccgccg gtggtgaagt cgatgatcgc
     9421 gcgccggttc tccggccggt gcgccgcatc cgcgaacagc tcccactgct cgccgggcag
     9481 cggcagcccc gaggcgggca cgggggagac gccgacgatc cggcgcagcc ggtgcggggc
     9541 cacggccagc agccgctggg ccaccgcgcc gcccatcgag tgccccacca ccgagaaccg
     9601 ctcccagccg aggcggtcgg ccagctccac caggtccagc gcggcctcga cggtggtgta
     9661 cgcgcccacg gcgtccttgg cccgtccgta gccgcgcaga tcgaccagcg cgtaggtgaa
     9721 cgtctcccgg tccaggtccg gcaggacggc cgcgtaggcg gaccggtcgg cgaaccagcc
     9781 gtgcacggcg aacaccttgt gggcgccgtc gccgtgcatt tcatggggca gcacgaagga
     9841 ggtcatgcga ccaccgtgac cggtgcgcgg gggctcggca agagcgcgga cggggcttgc
     9901 gtacggggcg agttggcggg tttccgcccg gttcacgcga tggtgtgatc acgtgttgcc
     9961 cggtggatgg ttgccggggg ccacgggtag ggccccggcc atgacgcagc cgttcgaact
    10021 cccgcacttc tacatgccgt accccgcgcg gctgaacccg catgtcgacg aggcgcgcgc
    10081 ccactcgacg gtgtgggcgt gtgagatggg catgctggag ggctccgggg tctgggcgca
    10141 ggcggatctg gaggcgcacg actacgggct cctgtgtgcc tacacccatc ccgactgcga
    10201 cggacccgca ctctcgctga tcaccgactg gtacgtgtgg gtgttcttct tcgacgacca
    10261 cttcctggag aggtacaagc gcacccagga ccgcgcggcc ggcaaggccc acctcgaccg
    10321 gctgccgctg ttcatgccgc tggacctggc gactgccgta ccggagccgg agaaccccgt
    10381 cgaggcgggc ctcgcggacc tgtgggcgcg caccgtgccg tcgatgtccg ccgactggcg
    10441 ccggcggttc gcgctggcca ccgagcacct cctcaacgag tcgatgtggg agctgtccaa
    10501 catcgatgag gggcggatcg ccaatccggt cgagtacatc gagatgcgcc gcaaggtggg
    10561 cggcgccccc tggtctgcgg gccttgtcga gtacgcgagc gccgaggtgc ccgcccgcgt
    10621 cgccggatcc aggccgctca gggtgctgat ggagaccttc tccgacgccg tgcacctgcg
    10681 caacgacctg ttctcctacc agcgggaggt ggaggacgag ggggagaaca gcaacggtgt
    10741 gctggtcctg gagaccttct tcggctgcac cacccaggag gccgccgaca ccgtcaacga
    10801 catcctcacc tcgcgcctgc accagtttga gcacaccgcg ctcaccgaag tgccggcgct
    10861 cgccctcgac aagggcctca cccccgacca ggtcgcggcg gtcgcggcct acacgaaggg
    10921 actccaggac tggcagtcgg gcggccacga atggcatctg cgctccagcc ggtacatgaa
    10981 cgagggcgcc gtctccgtct ccccgcggca cggcctgacc ggtccgggca cctccgccgc
    11041 cgacatcggc gccctgctcg cctcggccgc cgcagagcgg ctgcgcgcct actcccatgt
    11101 gcccttccag aaggtcggcc cgtccctgct gcccgacttc cgcatgcctt tcccgctggc
    11161 gctctccgag cacctggacg gcgcgcgcga gcgcctggcc ggctggatgc actggacagg
    11221 catgctccgg gagggggtct gggacgagga caagctcacc gcgtacgacc tcgcgctgtg
    11281 ctcggccggc ctcgacccgg acgcgacccc cgaggcgctc gacctcagcg cgcagtggct
    11341 cgcctggggc gcctacggcg acgactacta ccccctcgtc ttcggacacc gccgcgacct
    11401 ggccgccgcc cggctcacca cacgacggct gtccgcgtgc atgcccctcg acggcgaggc
    11461 ggtccccgcc ccggccaacg gcatggaacg cggactatgc gacctgtggg cccgtacgac
    11521 ggccgagatg ccccccggtg aacgcaccgc cctgaagcag tcggtcgacg cgatgaccga
    11581 gagctgggtg tgggaactct ccaaccaact gcagaaccgc atcccagacc cggtcgacta
    11641 tctggagatg cggcgcgcca ccttcggctc cgacctcacc ctgagcctgt gccgcagggg
    11701 ccggggcccc gcgatcccgc cggaggtcta ccgcagcggg ccggtgcgct cgctggagaa
    11761 cgccgccatg gactacgggt gcctcctcaa cgacgtcttc tcctaccaga aggagatcga
    11821 gtacgagggc gagatccaca acggtgtcct cgtcgtccag aacttcttcg gcgtcgacta
    11881 cccgaccgca ctcggcgtcg tacacgacct gatgacccag cgcatgcgcc agttcgagca
    11941 tgtggcggcg aacgaactgc cggtcatgta cgacgacttc gacctgcccg aagagacgcg
    12001 ggaggccgtc cgaggctatg tcctcgacct gcagaactgg ctggccggag tcctgcactg
    12061 gcaccagcgg gtcgaccgct acagggcccc ctacctcgcc cgccgtgccc acggcttcct
    12121 cccggacgca cgacccgcgt cgcccctctt gggcggtttc cagacacttt cgtgcggagt
    12181 gggacattca gggaacgtgg gtggaccgtc gtgagtcttc cggggcgagg ggaacagaac
    12241 acaacagaac acacgggggt gtgcgaacgt gaccgagatc atcgagagga tcaccgaggc
    12301 cgtcgacggg ggacagccgt cggctccgcc cgaactgacg ccgtacgtcg caccgttgcc
    12361 cgtcccgtcg gtcctgcggc ccgcgtccgc cgacgtgacg cacgagaccg agatcgccct
    12421 gcgcccgacc tggatccgcc tgcacccgca gctgccgccg accctgatgt gggggtacga
    12481 cggccaggtg ccgggcccga ccatcgaggt gcgccgcgga cagcgcgtcc gcatcgcttg
    12541 gaccaaccgc attcccaagg acagcgaata cccggtcgcc tcggtggagg tgccgctgcg
    12601 cacggacggc cgtccgcagg ccaccaccga gcccggccgc gagggcgtcg agccggacaa
    12661 ggacgtggcc gcgctgcccg cctggacggt gacccatctg cacggcgccc agacgggcgg
    12721 cggcaacgac ggctgggcgg acaacgccgt cggccacggt gacgcgcagc tgtcggaata
    12781 cccgaacgac caccaggcgg tgcagtggtg gtaccacgac cacgccatga acatcacgcg
    12841 gtggaacgtc cacacgggcc tgtacggcac ctacctggtc cgcgacgacg aggaggacgc
    12901 cctccacctc ccccgcgggg agcgggagat cccgctgctg ctcgccgacc gcaacctcga
    12961 caccgacgag gacggccgcc tcaacggccg gctgctgcac aagacggtga tcgtccagca
    13021 gcggaacccg gagacgggca agccggtctc catcccgttc accggcccgt acaccacggt
    13081 caacggccgc atctggccgt acgccgacgt ggacgccgcc tggtaccgct tccggctggt
    13141 caacgcgtcg aacgcgcgca tctacgacct cgtgctggtc gacgaggacg acaacccggt
    13201 gcccggcgtg gtccaccaga tcggcagcga cggagggctc ctgccgcggc ccgtgccgat
    13261 cgacttcgac gacaccctgc ccaccctgac cgccgccccg gccgagcgct tcgacctgct
    13321 cgtcgacttc cgtggcctcg cgggcaagcg gttccgcctg gtcgacaagg gccgcaaccg
    13381 gccggcgggc gtacccgacc cggccggtga cgtgcgctat ccggccgtcc tggagttccg
    13441 ggtccaggac tgtgagagca cggacacctt cgagctgcct gaggtgctct ccggctcctt
    13501 ccgccggctc acccacgacg tcccgcacgg ccaccgcctg atcgtgctca ccccgcccgc
    13561 caccaagggc gccggcggtc acccggagat ctgggagatg acccaggtcg aggacgccgg
    13621 cgacatccag gtacccacgg acgggatcat ccggctcacg ggtgcggacg gcaccacgaa
    13681 gacgtaccgg cgtacgtccc ggacgttcaa cgacgggctc ggcttcacca tcgccgaggg
    13741 cagctacgag cagtggagct tcctcaacct cgcgccgatc gtccacccca tgcacatcca
    13801 cctggccgac ttccagctgc tcggccgcga cgcctacgac gtctcgggct tcgacccggc
    13861 ggtgggcggc acggtcgagc cggtggcgtt cgacccgggg acccagctgc cgctggcccc
    13921 caacgagcgc ggccacaagg acgtgttccg tgtccccgga gggcagatcc tgcgggtcat
    13981 gggccggttc gacggcgcgt acggccggtt catgtaccac tgccacctgc tggagcacga
    14041 ggacatgggc atgatgcggc ccttcgtcgt gatgccgccc gaggccctga agttcgacca
    14101 cggcgcggca cacggcggcc atggcgagca gcacacgggt cacacgggct gaacacgcgc
    14161 gcgtgcggtg agggcggtga gggcgtggat gtcggcgagc gcggcccgtt ccgggccgtg
    14221 atgcctatga cttccctgtg ctgacccccg gtcagtctca ctcgttcgtg gctcgtcgcg
    14281 cccgcgtacg ccgggtagag caccagccgg aggcgaacca tggaagagac tgcactgcgt
    14341 cccaagccga tgcccggtca ggagcggcgg gactgtggca cccccggcac ccctggcacc
    14401 atcactggca cccccggcgc cggacagcgc ccgcacgccg cgcgccggcg cggaaggcgg
    14461 ctcaggaccc tgctgctcag cctgttcgtc gggacggtcc tggtgttgtc cggagtcggt
    14521 ctcggcacgg tcggcgcgtc ggtgatcggt atgagccggc tggcccagct gcgccatcag
    14581 gcgccgcccc cggccgcggc tgccacccgg tcggccgcgc cgtcaccggt cggcgtgagc
    14641 ctcggcgtgg aggccgtgga cgccgagaag tcgggggcgc tggtcgtcgg cgtccacgag
    14701 cccggccccg cccacatcgc cggcctggtc gtcggcgacg tactcctgcg cttcggcggg
    14761 acgcgcctcg ggacggccgc cgacctcgcg cgggccgtct cccgcgcccg tcccggagcc
    14821 gaggtcacgc tcacggtgcg gcaccgcggt ggcggctacc agcggctgac ggccgtcccc
    14881 ggcgtcgtca cctgacctcc cgccgccacc cgcgaccggc gacatcgtgg ccgcgggacc
    14941 ccgtaaccgg ctcgcgcggg cctccgtgtc cgggcaggat gctgcccgta gtcctttgcc
    15001 ccgcccccag acgtccccgg aggcctggat gaccggtagc atgcccgccc ccttcacggc
    15061 cgacgactac agggcccgca tggagcgcgc cgcgcgctgt gccgccgagg ccggtcttgc
    15121 gggcctgctc gtggcgccgg gaccggacat ggtgtggctc accggctacg cgcccacagc
    15181 ggtcaccgaa cggctcaccg tgctcgtcct cgccgccgga cgcgaccccg tgctggtcgt
    15241 accgaccctg gaggcaccgg acgccgagaa ggcggccggc gcgtccgccc tgaccctgcg
    15301 cggctggacc gacggcacgg acccctacgc ggtcaccgcc gccctcctcg acgccggcgg
    15361 ccgcttcggg atcagcgaca acgcctgggc gatgcatctg ctcggcctgc agaagatcct
    15421 gcccggcacc tcctacgccg ccctcaccga cgcgctgccg atgctgcgcg ccgtgaagga
    15481 cgcggcggaa ctggaactgc tcgcgtccgc cggagccgcc gccgacgccg cgttcgagga
    15541 gatccgcaag gtgtccttcg ccggtcggcg cgagtccgac gtcggccgcg acctcgccga
    15601 cctgctgcgg cgcttcggcc actcacaggt cgacttcacc atcgtcggct ccggacccaa
    15661 cggggccaac ccgcaccacg aggtcggcga ccgcgtcatc cgcgacggcg acatggtcgt
    15721 cctcgacttc ggcggcctca aggacggcta cggctccgac accagccgca ccgtgcacgt
    15781 gggtgagccc acggacgagg agcggaaggt ccacgacatc gtccgcgcgg cccaggaggc
    15841 gggcttccgc gcggtgcgcc cgggtgtcgc ctgccaggag gtcgaccggg ccgcccgtgc
    15901 ggtgatcgcc ggcgccgggt acggcgagta cttcatccac cgcaccggcc acggcatcgg
    15961 cgtcaccacc cacgagccgc cgtacatgat cgagggcgag gcacagcccc tcgtacccgg
    16021 catgtgcttc tccgtcgagc ccggcatcta cctgcccggc cgcttcggag tgcgcatcga
    16081 ggacatcgtc acggtgaccg cggacggcgg ccgtcgcctc aacaacacga ctcgtgacat
    16141 ggtcatagtg gactgaccgg gtggccccgg acaccaggag acgtacgcac cctcgacgac
    16201 accaccccga acggcaacgg cgcgacatga cccaggcacc gacacccacc gcggacaccg
    16261 tccgcagact ggttagtacg ctgctcaagg agagcgcgga cagcacctcg gggccggacg
    16321 tgcggcccgt cgcggagggc ggcgagcact ccacgtggtg ggtcggcacc cgccatgtgc
    16381 tgcgcctcgc ccccgaccgc gacgccgccg cccggcagcg ccgcgaactg cgcctgcgcg
    16441 acctcgtccg gccgcacgtc cccgtcaccg tccccctcag cgtggcgcac ggcgaatggg
    16501 ccccgggact gacctacacg ctcgacacca aggtgcccgg cggcacggga gaggagcacg
    16561 acgtctccgc cgtcggcgag gccgacctgt ccggcctgct cacggcactg cgccaggtac
    16621 cggtacggca ggcggagacg ctcggcgtgc cacgcgtcgc gccgcgctcc ctggaggcgc
    16681 tgcgccggat ggccgtacgg gccgcggaac ggctcggcgc cgccgacgag ttcgaccccg
    16741 ccctgatcct gcagctcacc ccggccggcg ccgcccagct cgccgcacag cccggcacgg
    16801 ccgtcctggt gcaccacaac ctcaggggcg agcacctcgt ggtgagcgcc gacggccggg
    16861 tgcgcggcat cctcgactgg accggcgtgg tcgtcggcga ccccgccgag gacatcgccg
    16921 ggctcgccct cgccgtcggc tccggcgcgg ccgtacgcgc cgccaccctc gccggctacg
    16981 gcgcccgccc ctgcctgcgc ggcctgtggc tggcccgctg cgacaccgtc gtcaggctca
    17041 tgaaccgcct ggacggccat gacaccggcc ccctcccgct gctgcgcacc cagctgcggc
    17101 gcgcctggga ggcgatcctg ctcgagcggg tgaccgactt ccgggacgag gagacgcgcg
    17161 aggagctgta gccccgccgg gtcagccctg cgtcagtacg acgcacgact cgccgggcac
    17221 cagcagcagc ccgtcggccc ccggcgcctc caccgggtcc catgcggcca ggactcgtac
    17281 ttctccggcg cccaggggga tcgcggccgg ctccttgccc aggttgacgg ccacccggac
    17341 gtccccgcgc cggaaggcca gccagcgggc ctgctcgtcg tacgccacct tggtgtcggc
    17401 gaggtcggga tcggtgaggt ccgcctcctc ccggcgcagg gcgaccagcc ggcggtacca
    17461 ggccagcacg cgcgcgtggg gctcgcgttc cggctccgac cagtccaggc aggagcgctc
    17521 gcgggtcgcc gggtcctgtg ggtcgggcac gtcctcctcg gcccagccgt gcgccgcgaa
    17581 ctcccgccgt ctgccctgcc gtacggcctg cgccagctcc gggtccgtgt ggtcggtgaa
    17641 gaactgccac ggggtgcccg cggcccactc ctcgcccatg aacagcatcg gcgtgaacgg
    17701 cgcggtcagc gtcagcgcgg cggcacaggc cagcagaccg ggggacagcg actgggacag
    17761 gcggtcgccc tgggcgcggt tgccgatctg gtcgtgggtc tgggagtagc cgaggagccg
    17821 gtgcccggcc accgtcgccc ggtccagcgg gcggccgtgg tggcggcccc ggaagccgga
    17881 gtaggtgccg tcgtggaaga aaccgccgga gagggtcttg gcgagggcga cgaacggggc
    17941 gcgggcgaag tccgcgtagt agccctggga ctcgccggtc agcgcggtgt gcagggcgtg
    18001 gtggaagtcg tcgttccact gcgcgtgcag gccgaggccg tgctccgcgc gcggggtgat
    18061 cagccgcggg tcgttgacgt cggactcggc gatcaggaac agcggtctgc ccagctcgga
    18121 gcagaggccg tccacggcgg ccgacagctc ctccaggaag gggtacgcgc gcgtgtcccg
    18181 cagcgcgtgc acggcgtcca gccgcagacc gtcgatccgg tagtcgcgca gccaggccag
    18241 cgcactgccc acgagatacg cgcgcacctc gtccgaaccg ggcgcgtcca ggttgaccgc
    18301 ggctccccag ggagtgtggt gcgtctcggt gaagtacggc ccgaacgcgg gcagatggtt
    18361 cccggacggc cccagatggt tgtgcacgac gtccaggacc acccccagac cgagttcgtg
    18421 cgcccggtcg acgaaccgct tcagcgcctc cgggccgccg tacggttcgt gcaccgccca
    18481 cagcgagacg ccctcgtacc cccacccgtg ccgccccggg aaggggcaca acggcatcaa
    18541 ctccacatgt gtgacgccca gttccaccag atgcccgagc cgctcggcgg ccgcgtccag
    18601 ggtgccctcg cgggtgtacg tccccacgtg cagctcatac aggaccgccc ccggcagcgg
    18661 gcgccccgcc cactcggcac gccacgcgta ccgctcctgg tccacgaccg cgctcggacc
    18721 gtccgggccg tcaggctggt ggcgcgagca cgggtcgggc agcacgggac cgtcgtccag
    18781 cgcgaacccg taccgcgtcc cgtcctgcgc cggcgactgt ccggtccacc accccgcccg
    18841 ctcggggttg cgctccaacg cgcgcgtggc gccgtcgcaa tggagcgtca cacggtctgc
    18901 ctgcggtgcc cacacctcga actgcacgga cggttcccct tcgtctgttc accgtgatgt
    18961 agcccgtcca tcgtgccgtg accgggacgg atgcgccttg aatccttcct ttctccgcgg
    19021 gtgtcgccgg cagtacgcgc gcgtggtggt cgtttccccg ttttctggac acccggggtt
    19081 cactgaccga caatcacgag cgtgacgtcg tccttcgagt tcaacacgta ccccgcgcgg
    19141 ctctcggacg cggagcgcga caaggcgctg caggtgctcc gtgacggcgt cgccatgggc
    19201 cgtctgtcgc acgacacgtt cgtgcgccgt atggaactcg ccctggccgc gcgccgggcc
    19261 gacgaactcg ccgtgctgac cgccgaccta ccccgggaga accgtctctc gcgggtcctg
    19321 ttcggcaccg tcgaggcggt ctccggcttc accgtacggc tgcgcaccgc ctggcaggcc
    19381 gagcggctgc ccaagctgat gctgccgcac gccggcaacg gccatccgct gcgcataggc
    19441 cgcgaccccg ccaacggact gcggctgaac cacgagaccg tctcccgcgt gcacgccgaa
    19501 ctccgccgtc agggcggcat gtgggtcctc agggacctcg gctcgaccaa cggcaccacc
    19561 gtcaacgggc gccgggtgat cggcgccgcc gtggtccgcg acggcgacca ggtgggtttc
    19621 ggccggatgg ccttccggct ctcgttgaac tgagcgaggc ccggcaccgg acacggtggc
    19681 cgaaaacgag ttgtccgccg cggtgttgac gtacccctga actcgtgact gactgtgcgt
    19741 acaccatgca caccaggtga aacgacggca ccacattgtg gaggtgtgcc ctgccgctcc
    19801 tccgctatcc gaccgtggac gagctgggcg cccgcgcggc cgcgctcgtc gcccgccgcc
    19861 ccgaggacgc ccggctgcgc cgcatcggca cctcccgcgc gggcgcgccc ctgtggctgc
    19921 tttccatcgg tcacggcagc cggcacgccc tcgtcgtggc cgggccgcac gccaacgagc
    19981 cggtgggcgg cgccaccgcc ctgcggctgg ccgagcgcac gctcgccgac tcccggctca
    20041 ccgaggccgc cgacaccacc tggaacctgc tgttgtgcct cgaccccgac ggctcccgcc
    20101 gcaacgaggg ctggctgtcc gggccgtaca ccctggacca ctacttccgg aacttcttcc
    20161 ggcccggctt cctggaacag cccgaatggc tgcccgaggg cgcggccgcc gccgtactgc
    20221 ccgagacgcg cgccctgctc cagctccagg acgagctgcg gcccttcctc cagtgctccc
    20281 tgcacggagt cgacgtcggc ggcggcttcg tggagctcac ccgcgacctg cccggcctgg
    20341 cccggcgcgt cgcgcactcc gcggcccggc tcggcatccc ccgcgaactc ggcgcgtacg
    20401 acaccctgta ctggcccagc gtcggacccg ccgtctaccg gatcccgccg ccgcgccggg
    20461 gtgacctggc cgcggccatc accgaggccg ccgtcgagtc gacctggttc cacccgcacc
    20521 ggtacggcac ggtgaccgcg atcgtcgagg cgccgatgtg gggcgtggcc gccgtggagg
    20581 acggctcacc gcccgccgac cgggacgcgg tgctgcgcac cgtcagcggc accctgcgcc
    20641 acgacacccg gctcctggac gacgtcctcg cccggatccg gccccagctg gcagccgtgc
    20701 ccgacgtggg cagcctgctc gcgccggtcg acgactattt actggtctgc cccggcctcg
    20761 ccgactcctg ggaccccgac accgacgacg gcagcgcccg cccgctgccc gcgctcaaca
    20821 ccgcccacct ggccgccctg cgcatctccg ggcgccggct ggcgctgcgc acggccgggc
    20881 tgctgcggcg gctcgtgctc agcaccgggc acgatccggc cggtgtcctg ccggacctgg
    20941 accggctcat cgacgcgtgg tgcgcggact accgcgacgg ctgcggtgcg cgctggatcc
    21001 cggtggcccg ccaggccgag taccaggcgc gtgtcgtgct gagcgcgttc gaactggcac
    21061 ggcagcacgc gcgcgtgccg tcccgttcgg gtgagtcggg ctggggtgcc ggcgccgccg
    21121 tgccgatgca ccgggaatga cgtacttcaa gcaagcgacc gccgtacgcg gcgccctgct
    21181 ggcggcggcc gccctcgttg ccgcctgccc cgccccggcc gcccaggcgg cggcccggga
    21241 cgcccactcc ggcaactggc tctacctcac cgtcacccgg ggcgacacgc ggtccggcga
    21301 catgcgcggc accctgctgc tgtgcgaccc gcccctgggc cacgcccacg cggccgaggc
    21361 ctgcgccgaa ctggaggcgg cggacggcga catcggcagc ctccgggcga atgcggacgc
    21421 cgtctgcccg atgatctacg ccccggtcac cgtccgcgtg ttcgggcagt ggcacggccg
    21481 gaccgtccag aacgagaaga cgttctccaa ctcgtgcgcg atggaagcgg ggacggggga
    21541 ggtgttccgg ctggacgact gagtccggcc gggcagggcc gcgcgggcac gcgtgtgtgg
    21601 gacgtgacgg tgccccacgc acgcgtgccg gtctcgcccc gccactctcc ccgtgccggg
    21661 cctcacgcca cccgctcgcg cgcgtactgc gccgccacga ggaccgtacg ggactggtgc
    21721 tccacctggt gctccagcgg cacccagcgg gcccggaaac gctcggcgaa ggcgtcgcac
    21781 caggaggcga cgagctgttc gagcccggga gcggcgcggt cgtcggcctc ctggaggacc
    21841 cgtagcagca tcgccgccgc ccgcagcggc agccgccgtc cgaaggcgtc cacactgccc
    21901 acgtatgccc gggtggtgtc gatgggtggg gtgtggatcc agtcctcggc caggcccggg
    21961 atcagctcca gtgcccactt cgcggcccgc agcagtggcc cctcggggcc gtccagccgt
    22021 ggcagggcct cggccagcac ccgctccacc tccagcgcgt cccgctgcag ccggtgcgcg
    22081 agttgccgca tcgccgccac gggggcgggg tgcggagccg ggtcgtccac caggtcgctg
    22141 gcccacatcg gcacctccac caccgcggtc aggccgccgt accggtgggc gtggtaccag
    22201 gtgctgtgcc gtgc
//
