LOCUS       NZ_CP106798            31354 bp    DNA     linear   CON 01-NOV-2023
DEFINITION  Streptomyces sp. HUAS 15-9 chromosome, complete genome.
ACCESSION   NZ_CP106798
VERSION     NZ_CP106798.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. HUAS 15-9
  ORGANISM  Streptomyces sp. HUAS 15-9
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9258818)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 169.8x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/01/2023 03:42:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,774
            CDSs (total)                      :: 8,679
            Genes (coding)                    :: 8,175
            CDSs (with protein)               :: 8,175
            Genes (RNA)                       :: 95
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 504
            CDSs (without protein)            :: 504
            Pseudo Genes (ambiguous residues) :: 0 of 504
            Pseudo Genes (frameshifted)       :: 260 of 504
            Pseudo Genes (incomplete)         :: 328 of 504
            Pseudo Genes (internal stop)      :: 29 of 504
            Pseudo Genes (multiple problems)  :: 107 of 504
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:51:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3863140
            Orig. end                         :: 3894494
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP106798.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo Ping.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..31354
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="11"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..31354
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31354
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:17354](-)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(14001..17354)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            complement(163..570)
                     /locus_tag="N8I87_RS17675"
                     /old_locus_tag="N8I87_17675"
     CDS             complement(163..570)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N8I87_RS17675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="N8I87_17675"
                     /product="hypothetical protein"
                     /protein_id="WP_263209955.1"
                     /transl_table=11
                     /translation="MPTRRAAARLPALTAHWPLAAMPTRRAAARLPALTAHWPLAAMPT
                     RRAAARLPALTAHRPLAAMPTRRAAPPAPALTAHRPLAAMPTRRAAARLPALTAHRPQV
                     AKPSQCAAARLMRSRPTGRKSPSPPGVPSPG"
     misc_feature    596..610
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     gene            734..1219
                     /locus_tag="N8I87_RS17680"
                     /old_locus_tag="N8I87_17680"
     CDS             734..1219
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015663063.1"
                     /locus_tag="N8I87_RS17680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17680"
                     /product="diadenosine tetraphosphate hydrolase"
                     /protein_id="WP_263209957.1"
                     /transl_table=11
                     /translation="MTVGWRKDRIGSALRGENPSVLARLESGFAVIGDVQFLPGYSLLL
                     VDDPSVQRLSELPQIRRLAFLSDMDKLGEAVERACKRLDPAFRRVNLEILGNTDPFLHV
                     HVWPRYDWEPPDLVGRPVWLYPRGSWGNERHALGPQHNAVRKAITDELTQGRRRETP"
     gene            complement(2065..2940)
                     /locus_tag="N8I87_RS17685"
                     /old_locus_tag="N8I87_17685"
     CDS             complement(2065..2940)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007504308.1"
                     /locus_tag="N8I87_RS17685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17685"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_263209960.1"
                     /transl_table=11
                     /translation="MAPAYDWQLTEDLDAFLSRAGAFLRSRPALHTVQLTVTDVLRTRG
                     LNVYGEGSPLFGTLTDENGTVRATLLHTPPHQLSFTALTAEEADALAARLLDTGHPVPA
                     VAAERASAEAFVEAWQRRSGASGELRMRQRLYRLGELAVPEPVPEGRARSVGPADRNLL
                     RRWVVEFSEAVGEPGFIAPDEWADARIAYGGTTLWETPDGTPVSLAGVTRQVAGQIRIG
                     PVYTPAHLRGRGYAGAATAEASRAARAAGAKEVLLFTDLANPTSNALYRRIGYREVADF
                     AAYRFRGEGG"
     misc_feature    complement(2917..2933)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.88"
                     /tool="antismash"
     gene            complement(2987..3589)
                     /locus_tag="N8I87_RS17690"
                     /old_locus_tag="N8I87_17690"
     CDS             complement(2987..3589)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006375521.1"
                     /locus_tag="N8I87_RS17690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17690"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_263209962.1"
                     /transl_table=11
                     /translation="MATAHERIPERQCPELDGHGLCLRRWDATADLDAATWLRGRSDPE
                     FQRWNTPLLAVTDLDGARASLHKQAENEANGNCAHFCVTDADSGTALGHIGLNMIDRVM
                     RTARVGYWVLPEARGRRVATRALTLASSWAFTELGLHRLELGHAVGHDASCRIARKCGF
                     LYEGTLRGAMFEAGRLDAFRDVHLHARIATDPEAHEG"
     gene            complement(3678..4082)
                     /locus_tag="N8I87_RS17695"
                     /old_locus_tag="N8I87_17695"
     CDS             complement(3678..4082)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016436583.1"
                     /locus_tag="N8I87_RS17695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17695"
                     /product="Zn-ribbon domain-containing OB-fold protein"
                     /protein_id="WP_263216521.1"
                     /transl_table=11
                     /translation="MVSPGFDVPEVDAFTRTYWEAAKEGRLLIRRCRAPGCGRAHHYPR
                     EFCPFCWGEDVTWEEASGRATLYTWSVVYRNDLPPFGDRTPYVAAVVDLAEGPRMMTEV
                     VGCEAEELRAGAELAVVFREGIAVFRPEGD"
     gene            complement(4154..4600)
                     /locus_tag="N8I87_RS17700"
                     /old_locus_tag="N8I87_17700"
     CDS             complement(4154..4600)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020121734.1"
                     /locus_tag="N8I87_RS17700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17700"
                     /product="DoxX family membrane protein"
                     /protein_id="WP_263209964.1"
                     /transl_table=11
                     /translation="MDAIWLSGAQWLAVLRVGLGLWWLESWRHKDKKTWFTGSGIAWAA
                     DMAEKHRWNAVRSGFEAVVKPRPKTMAYVVAYAELALGLGLIAGFLTPVALVGGLLLNL
                     LYFVLMIHDWAEQGQNSMMALISVVGLFGMAWQTWSVDAALGWF"
     gene            4819..6039
                     /locus_tag="N8I87_RS17705"
                     /old_locus_tag="N8I87_17705"
     CDS             4819..6039
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029639.1"
                     /locus_tag="N8I87_RS17705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17705"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_263209965.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.6e-14, bitscore:
                     51.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADSSDSSTPARSLAQPTAHPTAHPVYVIGGGPGGLAVAHSLRAR
                     GIRAVVLEKSDRVGASWRRHYDRLRLHTTRRLSGLPGLPMPRRFGRWVSRDDVVRYLEK
                     YSEHHELEIVTGVEVSRVERSADGTGWLLHASGGRELTGGAVVVATGFNHTPRVPDWPG
                     RDAYAGEFLHAGEYRNAKPYAGRDVLVVGVGNTGAEIAVDLVEGGASRVRLSIRTAPHI
                     VRRSTAGWAAQYSSVLIRRLPVGLVDRLARPMARLSVPDLSAQGLPRPDTGLYSRAKEG
                     AVPVLDVGLIDAVRKGQVEVVAAVEAFEDGKVVLADGSRVSPDAVVAATGYARGLEGLV
                     GHLDVLDERGRPVVHGGATPKNAPGLYFTGFTNPISGMFREMAIDAEKIAKAVARTAAG
                     QLSRISS"
     gene            6191..7717
                     /locus_tag="N8I87_RS17710"
                     /old_locus_tag="N8I87_17710"
     CDS             6191..7717
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020137678.1"
                     /locus_tag="N8I87_RS17710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17710"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_263209966.1"
                     /sec_met_domain="DAO (E-value: 3e-08, bitscore: 32.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHVARERQLSRHSQRSQLPQLSRRSLLGGAAAGAVGLTAATAGTA
                     SAASTRTVDVVVVGGGLAGLTAARDLVAGGRSVVVLEARDRVGGRLVNLKLANGSFTEG
                     GGEFVGPTQDRIKALADSLGVATFATYNAGNNLLYKDGKRTPYDTSGLLGSVPPVDAAG
                     LANAAIVQSELDSMAKQVPVDAPWTAARAAEWDRQTFESWLNAHAVIPSAKFLLDVACT
                     SVFSAQPRELSLLYVLYYIGAAGNASTAGTLERLTDTANGAQDSRFVGGSQQVPLKLAA
                     TLGDRVVLGAPVRSIAQSGGRYVVTADGITVTATRVVVAVPPPLAARISYDPLLPAERD
                     QLCQRMPMGSIGKAIAVYDTPFWRADGLNGQAVSDSGVVRSTFDNSPPDASYGALMGFI
                     EADEMRAYDAASVDDVRAAVLKDYANYFGDKAKSPTSFVLQRWDNEGFSRGGPVAYAPP
                     GVLTEYGAALRKPVGGIHWAGTETSTYWNGYMDGAVRSGERAAKEVLEAL"
     gene            complement(7743..9161)
                     /locus_tag="N8I87_RS17715"
                     /old_locus_tag="N8I87_17715"
     CDS             complement(7743..9161)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019521522.1"
                     /locus_tag="N8I87_RS17715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17715"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_263209969.1"
                     /transl_table=11
                     /translation="MTRRLLLSYLGLAILVLAGLEIPLGWIYARGEISRASQSVERDAS
                     MLAEVTEENIEKGNLDALPDVVGDYATRTGGHVLVTDKQGIVLADSDPSGRTGISIAAQ
                     PDIARALRNRPTVATGDDLLSATMPGSSGTTIRGTLRLTYPMAEVNSRVHRIWGALALA
                     GACILAAVAIVAFTLARWITRPLRTLEAATAQLADGRLTDPPDATTGPPELRSLAASFT
                     HTATRLQQLLKAQQAFASEASHQLKTPLTALRLRLENFEPYLDPRAHGSLEESVGEVER
                     LSRMVQGLLALARLENSATTPEPVDLDTVIADRVAMWESLAAEQYVALAVTGRPAGRVW
                     AIPGALEQVIDNLVANALRVSPPGTTITLHRSPGTPAGVELHVVDQGPGMSEADRGRAF
                     DRFWRASDSHHDGTGLGLPIVRHLVNASGGEITLHPAPGTGLDAAVRLRPAPGGRSRGG
                     SGSPRSAPAAATAS"
     gene            complement(9158..9910)
                     /locus_tag="N8I87_RS17720"
                     /old_locus_tag="N8I87_17720"
     CDS             complement(9158..9910)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013006291.1"
                     /locus_tag="N8I87_RS17720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17720"
                     /product="response regulator transcription factor"
                     /protein_id="WP_263209970.1"
                     /transl_table=11
                     /translation="MRLLLIEDDDRIASPLTEGLGRYGFTVDHVRTGAAGLAGTDDSPD
                     LVLLDLGLPDMDGLDVCRSLRARSAVPIIMITARGEEADRIVGLELGADDYLAKPFGVR
                     ELVARIRAVTRRTSGALPFPAPTQQTAQPEAPGPQLLGTLELNRRTRQVHLSGAEISLT
                     PREFDLLAYLAEDPGTVHSRQQIMDSVWDPHFFGPTKTLDAHVAALRRKLGDPAWITTA
                     RGVGFRLTVPGHDAESGPEPGVETGAAG"
     gene            complement(10089..10682)
                     /locus_tag="N8I87_RS17725"
                     /old_locus_tag="N8I87_17725"
     CDS             complement(10089..10682)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N8I87_RS17725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="N8I87_17725"
                     /product="hypothetical protein"
                     /protein_id="WP_263209972.1"
                     /transl_table=11
                     /translation="MSSEHENATAPLPDAQVTAILGPSAPDSAQGGYGNRFEEDAFDYP
                     SPSPSHSWSSSDDSVVGSAEVTVAESEAEPGAEVTGSRWRETAVRHRSAVTAVAALALL
                     GGFGLALSTVSDTVTSDPNPGGTAQVSAPKSPGSPSLPPDATLPAEPPGGAVNTATPPT
                     QTALPPVTGDHGDHGDDDHGEQEQGREDGDHADD"
     gene            complement(10724..11137)
                     /locus_tag="N8I87_RS17730"
                     /old_locus_tag="N8I87_17730"
     CDS             complement(10724..11137)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716315.1"
                     /locus_tag="N8I87_RS17730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17730"
                     /product="peptidase"
                     /protein_id="WP_263209974.1"
                     /transl_table=11
                     /translation="MRALPRRALLAAPAAVLMFALTACGGGSDSGSGSSKSDTQQAAQG
                     TGGADAAGEAAGDTDDKKEPPLTGDIKQKAEAAAVAAHPGTVIKSEEDAEKPGMYAVEV
                     KKADGTSVEVYLDKSFKVTGTKQEGTEETENDG"
     gene            complement(11332..12801)
                     /locus_tag="N8I87_RS17735"
                     /old_locus_tag="N8I87_17735"
     CDS             complement(11332..12801)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602285.1"
                     /locus_tag="N8I87_RS17735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17735"
                     /product="MFS transporter"
                     /protein_id="WP_263209976.1"
                     /transl_table=11
                     /translation="MSKHRRVRSSDRTRALRARSFDRTQALRARLASLDMGGRHRRVRK
                     GGRRRAPSEALATLGARNFRRYLIGQLVSNIGTWMQRAAQDLLVLQLTGNSGSAVGILT
                     ALQFLPQTLFGLSGGVFADRFAKRRLLIVTQSAMGVQSLVLGVLTVTGAVNLWAVYLLA
                     FLLGTATALDSPARNAFVPELVGKERLANAVSLNSAQFNAARAIGPAVAGLAVAAAGTG
                     PVFLVNAASYLAVLYGLIAIRADALHAPKEKNPANTRMSDAFRAIRANPELLLPITVIA
                     FVGTFGFNFQVTISLIALTVFNSGSAAYGYLSAAYAIGSLVGALRGAGRRKPPTARRLV
                     TATVVFGTLEALAGLMPGYVTFLLVLLPTGLASVTVMTTANAMTQLNADPSMRGRVVSV
                     YLLVLLGGTPVGAPLVGLVSDSLGARFSLVLGGAISAVAAIVLSAVITARSRTTRERTP
                     LTAVASPPPISIDGRFHPESTPQSVARRPAA"
     gene            complement(12808..14004)
                     /locus_tag="N8I87_RS17740"
                     /old_locus_tag="N8I87_17740"
     CDS             complement(12808..14004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602284.1"
                     /locus_tag="N8I87_RS17740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17740"
                     /product="type III PLP-dependent enzyme"
                     /protein_id="WP_263209978.1"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 7.6e-16,
                     bitscore: 57.1, seeds: 500, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 1.1e-33, bitscore:
                     115.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQQLLQYVAESAAEDLPAYVYDLGDLREHAAAVRAALPERVQLF
                     YAAKANADPRLLDVLRDHVDGFEVASGGELHHVHFTCPDTPIAFGGPGKTPAELEHALQ
                     AGVERLHIESEQELHLLTGRLGERTVDVLLRVNLPIALGPVALAMGGRPSPFGLDPSHL
                     DRCLALIADDPRIRLRGIHVHLASGLDAAAHLDLARQVLTWVTERSDRHGVELTEVNLG
                     GGMEVDYADPDRRFDWAAFGAGLRRLLEGHPGLTLRIEPGRSVTVYCGWYVTEVLDIKR
                     SHGRAFAVLRGGTHHLRTPATKQHNQPFTVIPADSWDRPWERPEAEDELITLVGQLCTP
                     KDVLARNVHVGRLRVGDKIAFALAGAYAWNISHHEFLMHPAPQFHHLDHAPVPTGPLP"
     gene            complement(14001..15695)
                     /locus_tag="N8I87_RS17745"
                     /old_locus_tag="N8I87_17745"
     CDS             complement(14001..15695)
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669550.1"
                     /locus_tag="N8I87_RS17745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17745"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_263209981.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.4e-56, bitscore:
                     189.9, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLPSTTGAALATTDSPAQAADAVTAHTLLNCLIREVSAPERQVT
                     VDHDHLLLSLPRRDILLRVPLRRISLIGAHRFDGPIERHDDGDWSAIGWRELAGYIQDE
                     LQLRTGVANDEFLAQVADSRNTVHTVLEQRATAALPQDPYLESEQSLVFGHRFHPAPKS
                     RTGDPEDWLDYGPETGSRFPLRHLAVHRRLVREEGDLSRLDALHPYGRRDYVTLPVHPW
                     QYRLLGDHPALRRALAAGSIVDTGVVGPDFAPTASVRTLYQPDADTFLKFSLNVRLTNC
                     VRKNAAYELSGAVALNRLLHPVFTAIGQAHAGTSLLAEPGYRTLALDDDLCLVEGFGVI
                     VRTGLREHLRPGVTPLLAAAIADEHPTSSAHVSRLLARGDGDALAWWDAYLGLLLPPVL
                     TAYFEHGIVLEPHLQNVVVGVDNDGIPTQVIFRDLEGTKLVPEHHRQFLAALPEDVRTP
                     MTYDAERGWNRVAYCLLVNHTAEVLAALADTDPALEPALWGLVRDHLDAYSRGAGEPPR
                     LRALLSGVPLPAKANLLLRWSRQADRHADYVPLPSPLGEGFPREVTR"
     gene            complement(15768..17354)
                     /locus_tag="N8I87_RS17750"
                     /old_locus_tag="N8I87_17750"
     CDS             complement(15768..17354)
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602282.1"
                     /locus_tag="N8I87_RS17750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17750"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_263209983.1"
                     /sec_met_domain="IucA_IucC (E-value: 3.3e-39, bitscore:
                     133.8, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPYSSTTAELRQVRPDLVEPFMAALPGARATVLGRLWGALAREPL
                     PGVAGREHDAGTLSIRLTGGGQLTGPASVAERFAPVPADFTVRGPDGRIDEPTRLLSAL
                     GAPTQAASRLAAELDNSITNLALARAANHEPHEVRDSADAEQAVVDGHPQHPCCRTRTG
                     LSVAEVLAYAPEHHPVMELALVAVPADRWQATGDWPRELRDGDTVLMPIHPWQRDHVLA
                     HQPGLTVVDRTIAARPLLSMRTMSPLDTLPGCHIKTALDVQVTNYRRTISPAEVADGAP
                     LSELVTAVVDKTGHGENLRILRELAGGAILVNGEPSSSLAAMIREAGERHLGPDEIAVP
                     LTAVHATGASMISGDPVTWLAEFAALVLPPALTLLSMGVALEAHGQNTLVALRDGRPVR
                     VLYRDLDGVRIHPGRLARHGFSLPPLHGTRAGNDETALRTKLFGGLLSGVFSELVSVLS
                     RTHGADPEQLWAAVAAVGRRVYADLPDTGADREVFFGDTLPLKATIAMRLAEASGVAQW
                     TPVPNPLARHR"
     misc_feature    17449..17466
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.12"
                     /tool="antismash"
     misc_feature    complement(17500..17513)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.49"
                     /tool="antismash"
     misc_feature    17563..17579
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.99"
                     /tool="antismash"
     gene            17756..18526
                     /locus_tag="N8I87_RS17755"
                     /old_locus_tag="N8I87_17755"
     CDS             17756..18526
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602281.1"
                     /locus_tag="N8I87_RS17755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17755"
                     /product="response regulator transcription factor"
                     /protein_id="WP_263209986.1"
                     /transl_table=11
                     /translation="MRLLLIEDDDRVAGPLMEGLSRFGFTVEHARTGADGLAAAEAEMV
                     LLDLGLPDMDGIDVCRTLRLRSQVPIIMISARSDEVDRVLGLELGADDYLSKPFGIREL
                     VARIRAVFRRAGPAATGPVAALPPAAGPASGGDRPDPVARAQRIGPLAIDRRGRQVHLH
                     RTSVALAPKEFDLLAYLADDPGAVRTRQQILDAVWEPNYFGPTKTLDVHVAALRRKLGD
                     PAWIDNIRGVGFRLTPPAGPATRQVEENVRGGEG"
     misc_feature    17765..17767
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18523..20010
                     /locus_tag="N8I87_RS17760"
                     /old_locus_tag="N8I87_17760"
     CDS             18523..20010
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013006290.1"
                     /locus_tag="N8I87_RS17760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17760"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_263209989.1"
                     /transl_table=11
                     /translation="MTRRLLLSYLSLTLLVLLCLEVPFGYVYARGEMSRFTGNGQQAAV
                     MLAEVLEEKVEQRGTDIPEVVASFARRTRGHVVVVDTQGKLLTDSRNTMATGTDLSTQP
                     DIAAALANRSDSGTRQDPALDEDVFFATVPGASGSTVRCVVRASFPLTSVAAKVHDAWL
                     ALAAVGLGVLAAVALIALALARWITCPVRALEHATTQLADGTLKDLPATDLGPPELRRL
                     AASFVRTATRLQHLLKAQHAFASEASHQLKTPLTALRLRLENFEPHLDPRAQPGLDAAV
                     GEVERLSRMVHGLLALARLENAATTAEATDLDSVIADRAAVWAAFAGEHYVDMVVAGPR
                     IGRVWAIPDALEQIIDNLLSNALRVSPPHTTITLATAWANGAPATVELHVIDQGPGMTE
                     NQRRRAFDRFWRANDADHEGTGLGLPIVKQLARASGGEVSLRAAPGGGLDAVVRLRTAD
                     AHRTAHPRRARSAMWGRQDGVPPVPTGRPLAVSDWQQ"
     gene            20178..20924
                     /locus_tag="N8I87_RS17765"
                     /old_locus_tag="N8I87_17765"
     CDS             20178..20924
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602279.1"
                     /locus_tag="N8I87_RS17765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17765"
                     /product="response regulator transcription factor"
                     /protein_id="WP_263216524.1"
                     /transl_table=11
                     /translation="MRLLLVEDDDRIAGPIMEGLDRYGFAVDHVRSGGSALSASPADLV
                     LLDLGLPDMDGIDVCRALRARSAVPIIMITARSEETDRVVGLEVGADDYLSKPFGVREL
                     VARIRAVTRRTHPERHAPPHTGTATTGVPPQGSLHAQLPEGRGIQHLGPLTIDRRTRGV
                     TIDSRPLTLTPKEFDLLAQLAGDPGAVHSRQQILDAVWDPNYFGPTRTLDVHVSALRRK
                     LGDPAWIATVRGIGFRLTVPGDGTYA"
     gene            21044..23272
                     /locus_tag="N8I87_RS17770"
                     /old_locus_tag="N8I87_17770"
     CDS             21044..23272
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019075550.1"
                     /locus_tag="N8I87_RS17770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17770"
                     /product="acetate--CoA ligase family protein"
                     /protein_id="WP_263209992.1"
                     /transl_table=11
                     /translation="MLGSTHGTLTTDSRRARVIACGEPRPGPAVHGRAADVDDLDVSGR
                     PLYADVPDLDRFFRPGSVAVIGASDTEGRPNTGITRQLLAWAERVGARVHPVHPTRPSV
                     FGIPCVASVADLPEQVDLGVLLVADPLPVVEELAEAKVKFAVAFASGFAETGEEGAKAQ
                     ERLAAAVRRSGLRLLGPNTNLNAFERFRQDLEGPAIALITQSGHQGRPVFALQELGIRL
                     SHWAPTGNEADLETADFISYFAERPEVGAIACYVEGLKDGRAFLLAADRAARRKVPVVA
                     VKVGRTEAGARTAASHTGKLTGADDVVDAAMRQFGVVRVDGLDELQDTAALLARARAPL
                     ADGVVVYSISGGTGAHVADLAAGAGLSLPVLSEARQAELHQWIPEYLSVANPVDNGGHP
                     VGDRRGRKIIDSILDDPDVGVLICPVTGPFPPLSDRLVRDLVDAAEASDKLVCVVWGSP
                     VGTEAAYREVLLGSSRVATFRTVGNCLTAVRAYLDHHRFVRSYRSPFDEAPRTPSPSFK
                     KARALMQPGQQLSEHAAKQLLRAYGIRVPREQLVTSAAAAVRAAGQVGYPVVMKASGAQ
                     IAHKTELGLVKIGLTSASQVRDAYRELTDIARYEGVSLDGVLVCQMVERGVEMVVGVTH
                     DALFGPTVTVGLGGVLVEVLRDAAVRVPPFGEEQAQDMIAELRGRALLDGVRGRPPADV
                     DGLVEVVLRVQRMALELGNELAELDINPLMVLPRGQGAVALDALAVCR"
     gene            23269..24060
                     /locus_tag="N8I87_RS17775"
                     /old_locus_tag="N8I87_17775"
     CDS             23269..24060
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (8-254). E-value: 1.7e-62. Score:
                     202.9. Matches aSDomain:
                     nrpspksdomains_N8I87_RS17775_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133087.1"
                     /locus_tag="N8I87_RS17775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17775"
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="WP_263209995.1"
                     /transl_table=11
                     /translation="MSGDAVRHEAHGQVSYVTLDRPETLNALTPEDRNRLIGLLGEASA
                     DPGVRAVVLTGTGRGFCAGADLRGDAPGGERVPGDVSRTLRLGAQRLVSAVLDCEKPVI
                     AAVNGTAAGLGAHLALACDLVLAAESARFIEVFVRRGLVPDAGGAYLLPRLIGPQRAKE
                     LMFFGDALSAPDAERLGLVNRVVPDGELDKTAREWAARLAAGPTRALALTKQMVNASLD
                     AGRASAFAAEAAAQEINMTTEDAREGLRAFVERRSPKFRGR"
     aSDomain        23293..24030
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_N8I87_RS17775_ECH.1"
                     /evalue="1.70E-62"
                     /label="N8I87_RS17775_ECH.1"
                     /locus_tag="N8I87_RS17775"
                     /protein_end="254"
                     /protein_start="8"
                     /score="202.9"
                     /tool="antismash"
                     /translation="EAHGQVSYVTLDRPETLNALTPEDRNRLIGLLGEASADPGVRAVV
                     LTGTGRGFCAGADLRGDAPGGERVPGDVSRTLRLGAQRLVSAVLDCEKPVIAAVNGTAA
                     GLGAHLALACDLVLAAESARFIEVFVRRGLVPDAGGAYLLPRLIGPQRAKELMFFGDAL
                     SAPDAERLGLVNRVVPDGELDKTAREWAARLAAGPTRALALTKQMVNASLDAGRASAFA
                     AEAAAQEINMTTEDAREGLRAFVE"
     gene            complement(24064..24948)
                     /locus_tag="N8I87_RS17780"
                     /old_locus_tag="N8I87_17780"
     CDS             complement(24064..24948)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000375.1"
                     /locus_tag="N8I87_RS17780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17780"
                     /product="hypothetical protein"
                     /protein_id="WP_263209997.1"
                     /transl_table=11
                     /translation="MTRWFGDLNTAASLCAAQLPAAGLLAWIASFGHDDYGVGYGGAFG
                     VLCLLLFAPLLLPFLGLVQAFTLTLPSVALARLAARRFGGPGWAWHLAAPVAPAAAWGG
                     PTALLWDWSPVTTVASLTAVGVLPALGVGYVRTRAWRPWGVWWRSALASVPLFVLAFGG
                     GVLATVMGLAPEYKPPKLTAAQLAGVWRGPSGAELRLRPGGRAEVTRLPTEATFEEFAT
                     KDFVTCGGSGTWEPDSDPDDTGRDGVLLRLDGDCGEDTHWSVSGTEDAPELFVLFGDPD
                     AGELWILERAAAG"
     gene            25052..25672
                     /locus_tag="N8I87_RS17785"
                     /old_locus_tag="N8I87_17785"
     CDS             25052..25672
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007382783.1"
                     /locus_tag="N8I87_RS17785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17785"
                     /product="flavin reductase family protein"
                     /protein_id="WP_263209999.1"
                     /transl_table=11
                     /translation="MGGVMGHAGMAAAAVRYLRSVDAPPPGPVEALPRPELRCVGEDER
                     APVDQGEFRRVLGHFATGVTVVTAPAVDGEDGPAGFACQSFSSLSLDPPLVVFMVGRTS
                     TTWPRIARTGVFCVNVLGAHQGELCRGFAVRGADKFAGVAYGAAPVSGSPRLAGTLAWI
                     DCTVHAVHTGGDHLIVVGRVDALGTADVDTAPAPLLFHKGRFL"
     gene            complement(25669..26976)
                     /locus_tag="N8I87_RS17790"
                     /old_locus_tag="N8I87_17790"
     CDS             complement(25669..26976)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1137: Major
                     facilitator superfamily MFS 1"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003974568.1"
                     /locus_tag="N8I87_RS17790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17790"
                     /product="MFS transporter"
                     /protein_id="WP_263210002.1"
                     /transl_table=11
                     /translation="MTQTTEAIAAAQEPKSRRSPRIHRAWFVAAVTFVTITGAAAFRSL
                     PGLLIDPLHQEFGWSRGTIGAAVSVNLALYGLTAPFAAALMDRFGIRRVVAVALTVIAV
                     GSGLTVWMTAAWQLMLCWGLLVGLGSGSMALAFAATVTNRWFTTRRGLVSGILTAASAS
                     GQLIFLPLLSWMVETYDWRPAAVTVSLTALAVVPFVWLLLRDHPADVGQKPYGAEEFVP
                     KPEPVTGAARRTVTVLLSAVRTGPFWLLAGTFAICGASTNGLIQTHFVPAAHDHGMPVT
                     AAASLLAVIGVFDVAGTIASGWFTDRFEPRRLLAVYYALRGISLLFLPMLLAPSVHPPM
                     IFFIVFYGLDWVATVPPTLALCREQYGEDSAIVFGWVLASHQVGAALVAFLGGVARDVF
                     GSYDMVWYASGALCAAAALMALVIRRRAAVPVAVAA"
     gene            complement(27069..28118)
                     /locus_tag="N8I87_RS17795"
                     /old_locus_tag="N8I87_17795"
     CDS             complement(27069..28118)
                     /NRPS_PKS="Domain: PKS_ER (14-269). E-value: 3.8e-13.
                     Score: 41.2. Matches aSDomain:
                     nrpspksdomains_N8I87_RS17795_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967149.1"
                     /locus_tag="N8I87_RS17795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17795"
                     /product="Zn-dependent alcohol dehydrogenase"
                     /protein_id="WP_263210005.1"
                     /sec_met_domain="ADH_N (E-value: 9.4e-27, bitscore: 92.0,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3e-19, bitscore:
                     68.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGVMFDGRQVQVVDDLKVRDPGPGEVLVSISAAGLCHSDLSVVD
                     GTIPFPVPVVLGHEGAGVVEAVGEGVRHVSPGDHVALSTLANCGACADCDRGRPTMCRK
                     AIGRPGKPFSRGGQPVHQFASNSAFAERTVVKAVQAVRIPEDIPMPSAALMGCGVLTGV
                     GAVLNRARVGLGDTVLVIGTGGIGLNVIQGARIAGARRIVAVDANPAKEPVARQFGATD
                     FLTSAEGVRDILPTGADHAFECVGRTELIRQAVDLLDRHGQAILLGVPPASAEASFLVS
                     SMYLDKSILGCRYGSSRPQRDIALYAELYRQGRLLLDELVTETYPVEDFEKARADAEAG
                     RVARGVLTF"
     aSDomain        complement(27312..28076)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_N8I87_RS17795_PKS_ER.1"
                     /evalue="3.80E-13"
                     /label="N8I87_RS17795_PKS_ER.1"
                     /locus_tag="N8I87_RS17795"
                     /protein_end="269"
                     /protein_start="14"
                     /score="41.2"
                     /tool="antismash"
                     /translation="DDLKVRDPGPGEVLVSISAAGLCHSDLSVVDGTIPFPVPVVLGHE
                     GAGVVEAVGEGVRHVSPGDHVALSTLANCGACADCDRGRPTMCRKAIGRPGKPFSRGGQ
                     PVHQFASNSAFAERTVVKAVQAVRIPEDIPMPSAALMGCGVLTGVGAVLNRARVGLGDT
                     VLVIGTGGIGLNVIQGARIAGARRIVAVDANPAKEPVARQFGATDFLTSAEGVRDILPT
                     GADHAFECVGRTELIRQAVDLLDRHGQAILLGV"
     CDS_motif       complement(27507..27590)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_N8I87_RS17795_0001"
                     /evalue="3.20E-01"
                     /label="PKSI-KR_m1"
                     /locus_tag="N8I87_RS17795"
                     /protein_end="204"
                     /protein_start="176"
                     /score="3.8"
                     /tool="antismash"
                     /translation="TVLVIGTGGIGLNVIQGARIAGARRIVA"
     gene            complement(28118..29272)
                     /locus_tag="N8I87_RS17800"
                     /old_locus_tag="N8I87_17800"
     CDS             complement(28118..29272)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015659698.1"
                     /locus_tag="N8I87_RS17800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17800"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_263210007.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.6e-17, bitscore:
                     63.1, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.8e-21, bitscore:
                     75.0, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 7.1e-19, bitscore:
                     67.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFGFTAADEAFRIEARAWLAEHAEPVQDRRSWERTLGAAGWIGL
                     GWPEGGYGNRTVGLTQQVVWSEEYARSAAPPRSGHIGENLLAPTLIAHGTDAQKSRFLP
                     PIAAGAELWCQGYSEPGAGSDLAGVRTSAVREPREPYYRISGQKIWTSLAHEADWCFVL
                     ARTDPDSRRHHGLSFLLVPMDQPGRIEVRPIRQMTGTSDFNEVFFDGARAHVEHVVGGE
                     GEGWQVAMSLLGFERGVSTLAQQIGFAQELERVLRTAVETGAAADPVVRDRLVRQWAEL
                     RAMRWNALRTLGGSGDPGTPSVAKLLWAGWHQRLGELAVRVRGAAAGVGPVDWSPSAPY
                     ELDAAQHLFLFSRADTIYGGSDQVQRTIIAERVLGLPREPKGVV"
     misc_feature    complement(29235..29249)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.19"
                     /tool="antismash"
     misc_feature    complement(29257..29271)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.69"
                     /tool="antismash"
     gene            complement(29383..30297)
                     /locus_tag="N8I87_RS17805"
                     /old_locus_tag="N8I87_17805"
     CDS             complement(29383..30297)
                     /NRPS_PKS="Domain: PKS_KR (8-183). E-value: 8.8e-16. Score:
                     50.3. Matches aSDomain:
                     nrpspksdomains_N8I87_RS17805_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006375534.1"
                     /locus_tag="N8I87_RS17805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17805"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_263210008.1"
                     /transl_table=11
                     /translation="MGNFLAGKVVAVTGAGRGIGRAVALAAAAEGARVVVNDYGVSTDG
                     TAPTSEVAEAVVKEIEAAGGSAVAVADDISTMAGGQRVVDVALSSYGRLDGAVCVAGIL
                     RERMLFNMTEEEWDPVVATHLKGTFTVFRAASAVMRKQKSGTLIGFTSGNHQGSVSQAN
                     YSAAKGGIISLVRSAALGLNKYGVSANAVAPVARTRMSAGVPMELKEIGEPEDVAALVV
                     YLLSERAREAGVTGQVYTVAGPKIAVWAQPRELRSAYCEGAWTPERIADFLPGSVGVDP
                     MPMLSQLEAMERAAQSGSRPNAQ"
     aSDomain        complement(29749..30273)
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_N8I87_RS17805_PKS_KR.1"
                     /evalue="8.80E-16"
                     /label="N8I87_RS17805_PKS_KR.1"
                     /locus_tag="N8I87_RS17805"
                     /protein_end="183"
                     /protein_start="8"
                     /score="50.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVAVTGAGRGIGRAVALAAAAEGARVVVNDYGVSTDGTAPTSEVA
                     EAVVKEIEAAGGSAVAVADDISTMAGGQRVVDVALSSYGRLDGAVCVAGILRERMLFNM
                     TEEEWDPVVATHLKGTFTVFRAASAVMRKQKSGTLIGFTSGNHQGSVSQANYSAAKGGI
                     ISLVRSAALGLN"
     CDS_motif       complement(30190..30264)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_N8I87_RS17805_0001"
                     /evalue="1.10E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="N8I87_RS17805"
                     /protein_end="36"
                     /protein_start="11"
                     /score="8.5"
                     /tool="antismash"
                     /translation="VTGAGRGIGRAVALAAAAEGARVVV"
     gene            30383..31309
                     /locus_tag="N8I87_RS17810"
                     /old_locus_tag="N8I87_17810"
     CDS             30383..31309
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007382789.1"
                     /locus_tag="N8I87_RS17810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N8I87_17810"
                     /product="cyclase family protein"
                     /protein_id="WP_263210010.1"
                     /transl_table=11
                     /translation="MSLPDEFHDIAKRVNNWGRWGAGDEIGTLNLITDEVVHGAAAAVR
                     TGRRVPLALALREDGVQTGMIPGRVNPLHAMVQINQEIFGPGTVACSDDVVTMGLQAAT
                     HWDALTHVSHSGKLYNGRPAHTVTAHGGAEFSGIDKARHIVSRGVLLDVARARGVDRLD
                     GGHAVTPEDLEAAEEFAGTRVRAGDIVLVRTGQVQVYLAGDKHGYGYPSPGLSVRTPEW
                     FHARDVAAVANDTLTFEIFPPEMENLWLPVHALDLVEMGMLQGQNWNLEELSTACGEEG
                     RYAFLLSAMPEPFVGATGTPVAPVAVL"
ORIGIN
        1 ggctagcggc ttgcggccgg tggggagtgg cgcgcggggg ctgagtggcg gcacgccggg
       61 tcggctagcg gcttgcggcc ggtggggagt ggagcgcggg ggctgggcgg cggcacgccg
      121 ggtcggctag cggcttgcgg ccggtgggga gctgggcacg catcagccgg gtgaaggcac
      181 gccgggaggg cttggcgact tgcggccggt gggacgggag cgcatcagcc gggcggcggc
      241 acactggctc ggcttggcga cttgcggccg gtgggcggtg agcgcgggga ggcgggcggc
      301 ggcacgccga gtcggcatag cggcgagcgg ccggtgggcg gtgagcgcgg gggcgggcgg
      361 ggcggcacgc cgagtcggca tagcggcgag cggccggtgg gcggtgagcg cggggaggcg
      421 ggcggcggca cgccgagtcg gcatagcggc gagcggccag tgggcggtga gcgcggggag
      481 gcgggcggcg gcacgccgag tcggcatagc ggcgagcggc cagtgggcgg tgagcgcggg
      541 gaggcgggcg gcggcacgcc gagtcggcat agcggcgagc ggccggtggg ggcggggtgc
      601 gcatcggcca agtgatggca ggcaccctgg gtggggttgg cggcttacgg cttaagggtg
      661 taggcgctcg gagatgacct gtaggcaaac cacctgatgg tcggtgggag agtacggggc
      721 ggggtggtgg gtcgtgaccg ttggctggcg caaggacagg attgggagcg cgctgcgggg
      781 tgagaaccct tcggtgcttg cgcggttgga gtcggggttc gcggtgatcg gggacgttca
      841 gtttctgccg gggtactcgc tgctcctggt ggacgacccg tcggtgcagc ggctgtcgga
      901 gcttccgcag atcagacgac tggcgttcct ctccgacatg gacaagctgg gcgaggccgt
      961 cgagcgcgcc tgcaagcgcc tggacccggc cttccgtcgg gtcaacctgg agatcctggg
     1021 aaacaccgac ccgttcctgc acgtccacgt gtggccgcga tacgactggg agccacccga
     1081 cctcgtgggc cgcccggtct ggctgtaccc aagggggagt tggggcaacg aacggcacgc
     1141 gctgggcccc cagcacaacg ccgtccgcaa ggcgatcacc gacgaactga cccagggaag
     1201 gcgccgggag accccctgaa gcaggccccg ggacagcaat tggaaccttc gggccaccca
     1261 agtcccgacg acctgctgat tccgccccct cactgtccca ttccttccaa caacgcccgc
     1321 caacacaact ggtgtgacgg aagcgatcga tgagacacgg ctaggcaccg gtgcgaccac
     1381 gcggaggtac ccggagtcac ccccacccgc ccactcaccc agccaaccat cggtccgccc
     1441 ggccacgccc ctccggccgc aagacgctga gccgacccgg cgtgccatct ctccgccgat
     1501 gcggccccgc cacccaccac ccgcaagccg ccaaccccac ccggcgtgcc accacccagc
     1561 cgattgcccc cccgccaccc accacccgca agccgccaac cccacccggc gtgccaccac
     1621 ccagccgatt gccccccccg ccacccacca cccgcaagcc gccaacccca cccggcgtgc
     1681 caccacccag ccgattgcgg ccccgctccc caccggccgc aagccgctaa gcccgcccgg
     1741 cgtgctggcg aggcgagacc gcgccccccg tcaccccggc ccagaacgca gcccacccaa
     1801 gggcccggcg cgcccaagcc ggccactttc cccgggccgc ccgctcgctt ctcacccgtg
     1861 ctggaacgcc cctagtcaag ggtggcccgc agggccatcg ccgaaggcga cgcggagcgg
     1921 aacgcagtgg agcggagcgc cctttactcg gggcgcggaa gcacgacact gacaaagaag
     1981 cgggcggccc cacggccact cgtcagcacc ggggcactgc acccacccca ccccacctca
     2041 cgcccgctca acccccacgc ccgctcaacc cccctccccc cgaaacctgt acgccgcgaa
     2101 atcggcaacc tcccggtatc cgatccgccg gtacagcgcg ttgctcgttg ggtttgccag
     2161 gtcggtgaag aggagtacct ccttcgcccc ggccgcccgc gcggcgcggc tcgcctcggc
     2221 tgtcgcggcg cccgcgtatc cgcgtccgcg gaggtgtgcg ggggtgtaga cggggccgat
     2281 cctgatctgc ccggcgacct ggcgggtcac cccggccagg gaaacgggcg tgccgtcggg
     2341 ggtttcccag agggtggtgc cgccgtaggc gatgcgcgcg tcggcccact cgtcgggggc
     2401 gatgaagccg ggttctccga ccgcctcgga gaactccacg acccagcgcc tcagcaggtt
     2461 ccggtcggcg gggccgacgg acctcgcccg tccctccggc accggctccg gtaccgccag
     2521 ctcccccagc ctgtagagcc gttggcgcat acgcagttcg ccggacgcgc ccgatcgccg
     2581 ctgccaggct tccacgaatg cctctgccga cgcccgctcg gcggcgaccg cggggacggg
     2641 gtggccggtg tcgagcagcc tggccgcgag ggcgtcggcc tcctcggccg tgagcgcggt
     2701 gaagctcagc tggtgcggag gcgtgtgcag cagggtcgcc cggaccgtgc cgttctcatc
     2761 cgtcagcgtg ccgaacagcg gtgacccctc gccatagaca ttgagtccac gcgtccggag
     2821 cacatccgtc accgtcagct gcaccgtgtg cagagccggc cgggagcgca ggaaggcgcc
     2881 cgctcgggag aggaaggcgt ccaggtcttc ggtgagctgc cagtcgtatg caggggccat
     2941 acctcatgat cccggcacaa cgtgcgccac gcccgcaatt gaccctctag ccctcgtgcg
     3001 cctcgggatc cgtggctatc cgtgcgtgca gatgcacatc ccggaacgcg tcgagccgcc
     3061 ccgcctcgaa catcgccccg cgcagtgtcc cctcgtacaa gaacccgcac ttccgcgcga
     3121 tccggcacga agcgtcatgc cctacagcgt gccccaactc cagccggtgc agccccagtt
     3181 ccgtgaatgc ccaggatgag gcgagggtca gcgcccgcgt ggccacgcgt cggccgcgcg
     3241 cctccgggag gacccagtag ccgacacggg cggtacgcat gacgcggtcg atcatgttga
     3301 ggccgatgtg ccccagcgcc gtaccgctgt ccgcgtccgt gacgcagaag tgcgcgcagt
     3361 tgccgttcgc ctcgttctcc gcctgcttgt gcagggacgc ccgtgctccg tcgaggtcgg
     3421 tgaccgccag caggggtgtg ttccagcgct ggaattcggg atcggacctg ccgcgcagcc
     3481 aagtcgccgc gtcgaggtcc gcggtcgcgt cccatcggcg aagacacaga ccgtggccat
     3541 cgagctcggg acactgccgt tcggggatgc gttcatgagc ggtagccatg ggcccattga
     3601 atcccctcgg cactgaatcc cccagcccat ctcagtcgcc cgcgggccgg aaccccactc
     3661 gcccgcgggt cgaaacctca gtcgccctca ggccggaaca ccgcgatccc ctcccggaac
     3721 acgacggcca gttcggcccc cgcccgcagt tcctccgcct cgcaccccac cacctcggtc
     3781 atcatccgtg gtccctccgc caggtcgacc acggcggcga cgtacggtgt gcggtccccg
     3841 aacggcggaa ggtcgttccg gtaaaccacc gaccaggtgt agagagtcgc ccggccgctc
     3901 gcctcctccc aggtcacgtc ctcgccccag cagaacgggc agaactcgcg ggggtagtgg
     3961 tgggcgcgtc cgcagccggg ggcccggcag cggcgtatca gcagccggcc ctccttggct
     4021 gcctcccagt acgtcctggt gaaggcgtcc acctccggca cgtcgaatcc gggcgatacc
     4081 atcagagcca tcccacctca cccttcagaa ccaccttgcc tcccctccat cagaaccacc
     4141 ctgcctcccc ccatcagaac caccccagcg ccgcatccac cgaccacgtc tgccacgcca
     4201 tcccgaacag ccccaccacc gagatgagcg ccatcatcga gttctgcccc tgctccgccc
     4261 agtcgtggat catgaggacg aagtagagga ggttcaggag caggccgccg accagggcca
     4321 ccggggtcag gaagcccgcg atcaggccca gtcccagggc cagctccgcg tacgcgacga
     4381 cgtacgccat cgtcttcggg cgcggcttga ccacggcctc gaaaccggag cgcaccgcgt
     4441 tccagcggtg cttctcggcc atgtccgccg cccaggcgat cccgctcccc gtgaaccagg
     4501 tcttcttgtc cttgtgccgc cagctctcca gccaccacag gccgaggccg acacgcagca
     4561 ccgccagcca ctgcgcgcca ctgagccaga tcgcatccat gaatctgacg gtacgtcaga
     4621 tctggaggaa agccgagacc tcgtcgagaa ttggccgggc ggctacaacc gcgcgcccac
     4681 aaccccgccg accccgccca caaccaggtc gcctacgtca ccggttcccc ccactcctcc
     4741 tacaggcgtg atcaatccgc aaccaattcc gaccttgacc gagacccatc aacgtgggac
     4801 gtggttacgc tcgcgctcat ggccgactcc agcgactcca gcacccccgc gagatccctc
     4861 gctcagccca ccgcccaccc caccgcccac cccgtctacg tcataggcgg cggccccggt
     4921 ggcctggcgg tcgcccactc gctgcgggcc cggggcatac gggccgtcgt cctggagaag
     4981 tccgaccggg tgggcgcctc gtggcggcgc cactacgacc ggctccggct gcacaccacc
     5041 cggcgactgt cgggcctgcc ggggctgccg atgccgcggc ggttcgggcg ctgggtgtcg
     5101 cgggacgacg tggtgcggta cctggagaag tactccgagc accatgagct ggagatcgtc
     5161 accggcgtcg aggtctcgcg cgtggagcgc tcggccgacg gcaccggatg gctgctgcac
     5221 gcctccggcg ggcgcgagct gaccgggggc gcggtggtcg tcgccaccgg cttcaatcac
     5281 accccgcgtg tgcccgactg gccggggcgg gacgcgtacg ccggggagtt cctgcacgcc
     5341 ggcgagtacc ggaacgccaa accttacgcc ggtcgggacg tgctggtcgt cggggtgggc
     5401 aacacgggtg ccgagatcgc cgtggacctg gtcgaggggg gcgcgtcgcg ggtgcggctg
     5461 agcatccgta ccgctccgca catcgtgcgc cggtcgaccg ccgggtgggc cgcgcagtac
     5521 tcgtccgtgc tgatccggcg cctgcccgtg gggctcgtcg accggctggc caggccgatg
     5581 gcccggctca gtgtgccgga cctgtcggcg cagggactgc cgcgcccgga cacggggttg
     5641 tactcccggg cgaaggaggg agcggtgcct gtcctggacg tagggctcat cgacgccgtg
     5701 cgtaagggcc aggtcgaggt cgtggccgca gtcgaggcgt tcgaggacgg gaaggtcgtc
     5761 ctggccgacg gcagccgggt ctccccggac gcggtcgtcg cggccaccgg gtacgcccgc
     5821 ggcctggaag ggctcgtcgg ccacctcgat gtgctcgacg agcggggccg gccggtcgtc
     5881 cacggcggcg ccaccccgaa gaacgccccc ggtctctact tcaccggctt caccaacccc
     5941 atcagcggca tgttccgcga gatggcgatc gacgcggaga agatcgcgaa ggccgtcgcc
     6001 aggaccgccg cgggacagct gtcccggatc tcgagctgac gtaggggtct tcaactcact
     6061 tacgtatgcg cctcgttact tgagagtcag atgtgacggg agagctgtac gtcgccaccg
     6121 cacggggtca gaatgtgagc actgctcaac tttccggctc cactccactc cctctcgccc
     6181 ctgacggagg atgcacgtgg cacgcgaaag acagctctcc cggcactccc agcgctccca
     6241 gctcccccag ctctcccggc gctcactgct cggcggtgcg gccgccgggg ccgtcggact
     6301 caccgccgcc accgccggta cggcgtccgc ggcgtccacc cgtaccgtcg acgtggtcgt
     6361 cgtcggcggc gggctcgcgg ggctcaccgc ggcccgtgat ctggtggcgg gcgggcggtc
     6421 cgtggtcgtc ctcgaagccc gggaccgggt cggcgggcgg ctggtgaacc tgaagctggc
     6481 gaacggcagc ttcaccgagg gcggcggcga gttcgtcggc cccacccagg accgcatcaa
     6541 ggccctcgcc gactccctcg gcgtggcgac cttcgccacc tacaacgccg ggaacaacct
     6601 cctctacaag gacggcaaga ggaccccgta cgacaccagc ggactgctcg gttccgtccc
     6661 gccggtggac gcggccgggc tcgccaacgc cgcgatcgtg cagtcagagc tcgacagcat
     6721 ggccaagcag gtgccggtcg acgcgccgtg gaccgcggcc agggccgccg agtgggacag
     6781 gcagaccttc gagagctggc tgaacgccca cgccgtcatc ccctcggcca agttcctcct
     6841 cgacgtggcg tgtacgtcgg tgttctcggc gcagccgcgc gagctctccc tgctgtacgt
     6901 gctgtactac atcggcgccg ccggcaacgc ctccaccgcc ggcaccctgg agcgtctgac
     6961 cgacaccgcg aacggcgccc aggactcccg cttcgtgggc ggctcccagc aggtgccgct
     7021 caagctggcg gcgacgctcg gggaccgggt ggtgctgggc gcgccggtgc gctcgatcgc
     7081 gcaatcgggc ggccggtacg tggtcaccgc ggacgggatc acggtcaccg cgaccagggt
     7141 ggtcgtggcg gtgccgccgc cgctggccgc gcgcatctcg tacgacccgc tgctgcccgc
     7201 cgagcgcgac cagctgtgcc agcggatgcc gatggggtcg atcgggaagg cgatcgccgt
     7261 ctacgacacc ccgttctggc gggccgacgg gctgaacgga caggcggtca gcgactccgg
     7321 ggtcgtacgg tcgacgttcg acaactcgcc gcccgacgct tcgtacggcg cgctgatggg
     7381 cttcatcgag gccgacgaga tgcgggcgta cgacgcggcg agcgtggacg acgtcagggc
     7441 ggccgtactg aaggactacg cgaactactt cggggacaag gcgaagtccc cgacctcttt
     7501 cgttctgcag cggtgggaca acgaggggtt ctcgcggggc ggaccggtcg cctacgctcc
     7561 gcccggggtg ctgaccgagt acggcgccgc gctgcgcaag ccggtgggtg gcatccactg
     7621 ggccgggacc gagacctcca cgtactggaa cgggtacatg gacggagcgg tgcgctcggg
     7681 cgagcgggcg gccaaggagg tgctggaggc gctgtaggtc gggtgcgcag gcccggggcc
     7741 ggtcatgacg ccgtcgcggc tgccggtgcc gatcggggcg agccgcttcc gccgcgtgac
     7801 cggccgcccg gcgccgggcg cagccgcacg gcggcgtcca ggccggtgcc cggcgccggg
     7861 tggagggtga tctcgccgcc ggaggcgttc accagatggc ggacgatggg caggccgagg
     7921 ccggtgccgt cgtggtggga gtcggaggcg cgccagaagc ggtcgaaggc gcggccgcgg
     7981 tcggcctcgg acatgccggg gccctggtcg acgacgtgga gttcgacgcc ggccggggtg
     8041 cccggcgacc ggtggagcgt gatggtcgtg ccgggcggtg agacccgcag ggcgttggcg
     8101 accaggttgt cgatgacctg ctccagcgcc cccgggatcg cccagacccg gccggcgggg
     8161 cggccggtga cggcgagcgc gacgtactgt tcggcggcca gcgactccca catggcgacg
     8221 cggtcggcga tgacggtgtc caggtcgacc ggttccgggg tggtggcgga gttctccagg
     8281 cgggccaggg cgagcaggcc ctgcaccatg cggctgaggc gttcgacctc gccgacggat
     8341 tcctccaggc tgccgtgggc gcgtgggtcg aggtagggct cgaagttctc caggcgcagg
     8401 cgcagtgcgg tcagtggggt cttcagctgg tgggaggctt cggaggcgaa cgcctgctgg
     8461 gccttgagga gttgttgcag ccgggtcgcc gtgtgggtga aggaggcggc gaggctgcgg
     8521 agttcgggcg ggccggtggt ggcgtccggc gggtcggtga gccggccgtc ggccagttgg
     8581 gcggtggcgg cctccagggt gcgcaggggg cgggtgatcc agcgggcgag ggtgaaggcg
     8641 acgatggcca cggcggccag gatgcaggct ccggccaggg cgagggcgcc ccagatgcgg
     8701 tgcacgcggg agttgacctc ggccatgggg taggtcaggc gcagggtgcc ccggatggtg
     8761 gtgccggagg agcccggcat ggtggccgac agcaggtcgt ctccggtggc cacggtcggc
     8821 cggttgcgca gggcacgggc gatgtccggc tgggcggcga tgctgatgcc cgtacggccc
     8881 gacgggtcgg agtcggccag gacgatgccc tgcttgtcgg tgacgaggac gtgtccgccg
     8941 gtgcgggtgg cgtagtcgcc gacgacgtcg ggcagggcgt cgaggttgcc cttctcgatg
     9001 ttctcctcgg tgacctcggc gagcatcgag gcgtcgcgtt cgacgctttg ggaggcgcgg
     9061 gagatctcgc ctcgggcgta gatccagccg agcggtatct cgaggccggc cagcacgagg
     9121 atcgccaggc cgaggtagct gagcagcaga cgtcgggtca tccggccgcc ccggtctcca
     9181 ccccaggctc cggcccggac tccgcgtcgt ggccggggac ggtgaggcgg aagccgacac
     9241 cgcgggccgt ggtgatccag gccgggtctc cgagcttgcg gcgcagcgcg gcgacgtggg
     9301 cgtcgagggt cttggtgggg ccgaagaagt gcgggtccca caccgagtcc atgatctgct
     9361 gccgggagtg gaccgtgccg gggtcctcgg cgaggtaggc gagcaggtcg aactcacggg
     9421 gtgtgagcga gatttcggct ccgctcaggt ggacctggcg ggtgcggcgg ttgagttcca
     9481 gggtgccgag cagctgcggt ccgggagcct cgggctgcgc cgtctgttgc gtgggcgcgg
     9541 ggaagggcag cgcgccactg gtgcggcggg tgaccgctcg gatacgggcc accagttccc
     9601 gtacgccgaa gggcttggcg aggtagtcgt cggcacccag ttccaggccg acgatgcggt
     9661 cggcctcctc tcccctcgcg gtgatcatga tgatcgggac ggcggagcgg gcgcgcaggc
     9721 tgcggcagac gtcgaggccg tccatgtcgg gcaggccgag gtcgagcagg accaggtccg
     9781 gggagtcgtc ggtaccggcg agtccggcgg caccggtgcg gacatggtcc acggtgaatc
     9841 cgtaccggcc gagcccttcg gtgagcgggc tggcgattct gtcgtcgtct tcgatgagca
     9901 ggagccgcat ggcgcaaggc tcgcacagct gtgccaggag agttgggctg ttcacgggaa
     9961 gccgcctggg acctgggagg tgtacggggc ggtgagcggg cgcggggtgc cgcccggccg
    10021 gtctgcacgg gaaggtggga gcggccgggc ggcgggagcg gggcggggac gacgccgacc
    10081 gtggggagtc agtcgtcggc gtggtctccg tcctcgcgtc cctgctcctg ctccccgtgg
    10141 tcgtcgtcac cgtggtcacc gtggtcaccg gtgacaggcg gcagagcggt ctgcgtgggc
    10201 ggggttgccg tgttcacagc gccgccgggc ggttcggcgg ggagcgtcgc gtccggcggg
    10261 agggacggtg agccgggtga cttgggcgcg gacacctggg cggtgccgcc ggggttcggg
    10321 tcggaggtga ccgtgtcgct gaccgtggac agcgcgaggc cgaagccgcc gaggagggcg
    10381 agtgcggcga cggccgtcac ggccgaccgg tgccgtaccg ccgtctcccg ccaccggctc
    10441 ccggtcacct cggcccccgg ctccgcctcc gactcggcaa ccgtgacttc ggcggagccg
    10501 accacgctgt cgtcggagga ggaccaggag tgggagggag agggcgaggg gtagtcgaag
    10561 gcatcctcct cgaagcggtt cccgtagcct ccctgtgcgg agtcgggggc cgaaggcccc
    10621 aggatcgccg tcacctgtgc gtccggcagt ggcgcggtgg cgttctcgtg ctcgctcgac
    10681 acctgtttct ccctcctcct tccggccggt cgacccgtgc gtctcagccg tcgttctcgg
    10741 tctcctcggt gccttcctgc ttggtgccgg tcaccttgaa ggacttgtcc aggtacacct
    10801 cgaccgaggt gccgtccgcc ttcttcacct ccaccgcgta catgccgggc ttctccgcgt
    10861 cctcctcgga cttgatcacc gtgcccgggt gggccgcgac ggccgccgcc tcggccttct
    10921 gcttgatgtc gccggtcagc ggcggttcct tcttgtcgtc ggtgtcaccg gcggcctcgc
    10981 ccgccgcgtc ggcaccgccc gtgccctggg cggcctgctg ggtgtcggac ttcgaactgc
    11041 cggagccgga gtcggaaccg ccaccgcagg cggtgagggc gaacatcagc acggcggcgg
    11101 gagcggcgag gagggcacgg cggggcaagg cacgcatgaa gggactccag atttcgggga
    11161 tgcggtgatc cgggagccgg accaccgggg gatgtcaacg accctaggaa gacgctgtcg
    11221 agagccggcc cagcagacgg agagcggaag cccagcagat gtccaaagtt tcgccaccga
    11281 tgccagagag tgcaccgatg ccagagggtg tgccgccgga tccgtctcgc atcaggccgc
    11341 cggtcggcgg gccacggact gtggggtgga ttcggggtgg aagcggccgt cgatggatat
    11401 cggcggcggt gatgcgaccg cggtgagcgg ggtgcgctcc cgggtggtgc gggagcgtgc
    11461 ggtgatcacg gccgacagga cgatggcggc cacggcggag atcgcgccgc cgaggacgag
    11521 gctgaagcgg gcgccgaggg agtcggagac caggccgacc agaggggcgc cgaccggggt
    11581 gccgccgagc aggacgagga gatagacgga gacgacgcgg ccgcgcatgc tcgggtcggc
    11641 gttcagctgg gtcatggcgt tggccgtggt catcacggtc accgaggcca gccccgtggg
    11701 caggagtacg agcaggaagg tgacgtagcc gggcatgagg ccggccaggg cctccagggt
    11761 tccgaagacg accgtggcgg tgaccaggcg gcgggcggtg ggaggttttc gtctgccggc
    11821 tcctcttagt gcgccgacga ggctgccgat ggcgtaagcc gcggagaggt aaccgtaggc
    11881 ggcggagccc gagttgaaga cggtcagggc gatcagggag atggtgacct ggaagttgaa
    11941 gccgaaggtg ccgacgaagg cgatgaccgt gatcggcagc agcagttcgg ggttggcgcg
    12001 gatggcgcgg aacgcgtccg acatgcgggt gttcgccggg ttcttctcct tgggtgcgtg
    12061 gagtgcgtcg gcgcggatgg cgatcaggcc gtagaggacg gcgaggtacg aggccgcgtt
    12121 gaccaggaag acgggtccgg tacccgcggc ggcgaccgcc aggcccgcca cggccgggcc
    12181 gatcgcgcgg gcggcattga actgcgcgga gttcaggctg acggcgttgg ccaggcgttc
    12241 cttgccgacg agttcgggga cgaaggcgtt gcgggccggg ctgtccagcg ccgtggccgt
    12301 gcccagcagg aaggccagca ggtatacggc ccacaggttc accgcgccgg tgacggtcag
    12361 gacgcccagg accagcgact gcactcccat ggcggactgc gtgacgatca gcaggcggcg
    12421 tttggcgaac cggtcggcga agacgccccc ggaaagaccg aagagggtct gcggcaggaa
    12481 ctgcagggcg gtgagtatgc cgacggcgct gccgctgttg ccggtgagct ggaggaccag
    12541 caggtcctgg gcggcgcgct gcatccaggt gccgatgttg gagacgagct gcccgatcag
    12601 gtagcggcgg aagttgcggg ccccgagggt ggcgagtgct tcgctcgggg cccgtcgcct
    12661 tccgcccttg cggaccctgc ggtgcctgcc gcccatgtcg aggctggcga gtcgggcgcg
    12721 gagggcctga gtcctgtcga agctgcgggc gcggagggcc cgcgtcctgt cactgctgcg
    12781 gacacggcgg tgcttgctca tggccttcta cgggaggggt ccggtgggga cgggagcgtg
    12841 gtcgaggtga tggaactgcg gcgcggggtg catcaggaac tcgtggtggg agatgttcca
    12901 ggcgtacgcc ccggccaggg cgaaggcgat cttgtcgccg acgcgcagcc gccctacgtg
    12961 cacattgcgg gccaggacat ccttgggcgt gcacaactgc cccaccagcg tgatgagttc
    13021 atcctcggct tcggggcgct cccagggccg gtcccagctg tcggcgggga tgacggtgaa
    13081 cggctggttg tgctgtttgg tggccggcgt gcgcagatgg tgggtgccgc cgcgcaggac
    13141 ggcgaaggcg cggccgtggc tgcgtttgat gtcgaggacc tcggtgacgt accagccgca
    13201 gtacacggtg accgagcggc ccggttcgat gcgcagggtg aggccgggat ggccctccag
    13261 caggcggcgc aggccggcgc cgaaggccgc ccagtcgaag cgccggtcgg ggtcggcgta
    13321 gtcgacctcc atgccgccgc cgaggttgac ctcggtcagc tccacgccgt gccggtccga
    13381 ccgttccgtc acccaggtca ggacctgccg ggcgaggtcg aggtgtgcgg cggcgtcgag
    13441 gccgctggcg agatggacgt ggatgccgcg cagccggatg cgggggtcgt cggcaatgag
    13501 ggcgaggcag cggtcgaggt ggctcgggtc gaggccgaag gggctgggcc ggccgcccat
    13561 ggcgagggcc accgggccga gggcgatggg gaggttgacc cgtagcagaa cgtccacggt
    13621 gcgctcaccg agcctgccgg tgagcagatg gagctcttgt tcgctctcga tgtgcaggcg
    13681 ctccactccg gcctggaggg cgtgttcgag ttcggctggg gtcttgccgg ggccgccgaa
    13741 ggcgatcggc gtatcggggc aggtgaagtg gacgtggtgg agttcgccgc cggaggcgac
    13801 ctcgaagccg tcgacgtggt cgcgcaggac gtccaggagc cgggggtcgg cgttggcctt
    13861 ggcggcgtag aagagctgga cgcgttcggg cagggcggcg cggacggcgg ccgcgtgctc
    13921 gcgcaggtcc cccaggtcgt agacgtaggc ggggaggtct tccgcggccg actcggcgac
    13981 gtactggaga agttgctgcc tcaccgggtc acctcgcggg ggaagccctc gcccagcggg
    14041 ctgggcagcg ggacgtagtc ggcgtgccgg tcggcctgcc gggaccagcg cagcagcagg
    14101 ttggccttgg cgggcagcgg gacgcccgag agcagggcgc gcagccgggg cggctcacct
    14161 gcaccgcggg agtaggcgtc caggtggtcg cggaccaggc cccacagggc gggttccagg
    14221 gcggggtcgg tgtcggcgag ggcggcgagg acttcggcgg tgtggttgac caggaggcag
    14281 taggccaccc ggttccagcc gcgctcggcg tcgtacgtca tcggagtgcg cacgtcctcg
    14341 ggcagggcgg cgaggaactg gcggtggtgt tcggggacga gcttggttcc ctccaggtca
    14401 cggaagatca cctgggtcgg gatgccatcg ttgtcgactc ccacgacgac gttctggagg
    14461 tggggttcga ggacgatgcc gtgctcgaag taggcggtca ggacgggggg cagcagcagg
    14521 ccgagatagg cgtcccacca ggcgagcgca tcgccgtcgc cgcgggccag gaggcgggag
    14581 acgtgggccg agctggtggg gtgctcgtcg gcgatcgcgg cggccagcag tggggtcacg
    14641 ccggggcgca ggtgttcgcg caggccggtg cggacgatga cgccgaagcc ctccacgagg
    14701 cagaggtcgt cgtcgagggc gagggtgcgg tagcccggct cggcgagcag ggaagttccg
    14761 gcatgggcct gcccgatcgc ggtgaagacg gggtggagga gccggttgag ggccacggca
    14821 ccggacagct cgtaagcggc gttcttgcgg acgcagttgg tcaggcggac gttgaggctg
    14881 aacttcagga aggtgtcggc gtccggctgg tacagggtgc gcaccgaggc ggtgggggcg
    14941 aagtccgggc cgacgacgcc cgtgtcgacg atcgagcccg cggccagggc ccggcgcagg
    15001 gcggggtggt cgccgagcag ccggtactgc catgggtgca ccggcagggt cacgtagtcc
    15061 cttcgcccgt acggatgcag cgcgtcgagc ctgctcaggt cgccttcctc gcgcaccaga
    15121 cgccggtgga cggcgaggtg gcgcagcggg aagcggctgc ctgtctcggg gccgtagtcc
    15181 aaccagtcct cggggtcgcc ggtgcgcgac ttgggcgcgg ggtggaagcg gtggccgaag
    15241 accagggact gctcggactc caggtacggg tcctgcggca gggccgcggt ggcacgctgc
    15301 tccaggacgg tgtggacggt gttgcgactg tcggcgacct gggccaggaa ctcgtcgttg
    15361 gccacgccgg tgcgcagttg cagttcgtcc tggatgtatc cggcgagctc gcgccatccg
    15421 atcgcggacc agtccccgtc gtcgtgccgc tcgatcgggc cgtcgaagcg gtgcgcgccg
    15481 atcagggaga tacggcgcag ggggacgcgg agcaggatgt cgcggcgggg cagcgacagc
    15541 agcaggtggt cgtggtcgac ggtgacctgg cgctcgggcg cggagacctc gcggatcagg
    15601 cagttgagca gggtgtgggc ggtgacggcg tcggcggcct gggcgggact gtcggtggtg
    15661 gcgagagcgg cgccggtggt actggggagg gtcatgcgga aggactccag tcggtgcaag
    15721 gagaggtgcg gggaggccgg ccgggcccgg cgggcggaag cggggtgtca gcggtggcgg
    15781 gccagggggt tggggacggg agtccactgg gcgacaccgg aggcttcggc caggcgcatc
    15841 gcgatggtcg ccttcagcgg cagggtgtcg ccgaagaaca cctcccggtc cgcgcccgtg
    15901 tcgggaaggt ctgcgtagac gcggcggccg acggcggcca cggctgccca caactgctcg
    15961 gggtcggcgc cgtgcgtgcg cgacagcacg gagacgagtt cgctgaagac gccgctgagc
    16021 aggccgccga acagcttggt gcgcagtgcg gtctcgtcgt tcccggcccg ggtgccgtgc
    16081 agcggcggga gcgagaagcc gtggcgggcg agtcggcccg gatggatgcg tacgccgtcc
    16141 aggtcgcggt agagcacccg caccggacgt ccgtcgcgca gcgcgacgag ggtgttctgg
    16201 ccgtgggcct ccagggcgac gcccatggac aacagcgtca gcgcgggcgg caggacgagt
    16261 gcggcgaact ccgccagcca ggtgaccggg tcgccgctga tcatgctggc tccggtggcg
    16321 tggacggcgg tgagcgggac ggcgatctcg tccggtccga ggtgccgttc gccggcctca
    16381 cggatcatcg ccgcgaggct ggacgagggc tcgccgttca cgaggatggc gccgcctgcg
    16441 agttcgcgca ggatgcgcag gttctcgccg tggcccgtct tgtcgacgac ggcggtgacc
    16501 agctcggaca gcggggctcc gtcggccacc tcggccgggg agatggtgcg ccggtagttg
    16561 gtgacctgca cgtccagcgc cgtcttgatg tggcagccgg gcagggtgtc gaggggggac
    16621 atggtccgca tcgacagcag cgggcgggcg gcgatcgtac ggtccacgac cgtgaggccg
    16681 ggctggtggg cgaggacgtg gtcgcgctgc caggggtgga tcggcatcag gacggtgtcg
    16741 ccgtcgcgca gttcccgagg ccagtcgccg gtggcctgcc agcggtcggc cggtacggcg
    16801 acgagcgcca gctccatgac ggggtggtgc tcgggcgcgt aggcgaggac ttcggcgacg
    16861 gacagtccgg tgcgcgtacg gcagcagggg tgctgcgggt ggccgtcgac cacggcctgt
    16921 tcggcgtcgg cggagtcccg tacctcgtgc ggctcgtggt tcgccgcgcg cgccagggcc
    16981 aggttggtga tgctgttgtc gagttcggcg gccagccgtg acgcggcctg cgtgggggct
    17041 ccgagggcgg acaggagccg ggtcggctcg tcgatccggc cgtcggggcc ccgcacggtg
    17101 aagtcggcgg ggaccggggc gaatcgttcc gccactgagg ccgggcccgt gagctgcccg
    17161 ccgcccgtga ggcggatgct gagggtgccc gcgtcgtgct cgcggccggc gacacccggg
    17221 aggggttcgc gggcgagtgc gccccagagc cggccgagca ccgtggcacg cgcgccgggg
    17281 agcgcggcca tgaagggctc gaccagatca gggcgcactt ggcgcagttc ggcggtcgtg
    17341 ctgctgtacg gcatggttca ccgtcccgtg gcatagaaag caagggagag gctgcggagg
    17401 cgaaaagaga gcgcaaatgc gagcgccgtc cgcgttcagc cgccgacaac gttacgggat
    17461 cgttagttaa ccgattgcca gcgcaaagga aggccggcat cagaatcgat ccagcattcc
    17521 gtccccttga atcggaaacg attcggggcg atgaagcccg cgctgtactt tcttaacagt
    17581 ctgctggcct gccgctgtca tttcattgac gttgtgctgt agcagggtcc gtagggtcga
    17641 tcgacagaca ggagacggta aaggaatacg gttgttcagg tttgccgaga gtaatccacg
    17701 cgacattcag cggctttccc gacgcggcgg accgccggct tgtgattctg tcggcatgcg
    17761 tctcttactg atcgaggacg atgaccgggt cgccggcccg ctgatggaag gcttgagccg
    17821 tttcgggttc accgtcgagc acgcccgtac cggcgccgac ggactcgcgg cggcggaagc
    17881 ggagatggtg ctgctggatc tgggactgcc cgacatggac ggcatcgatg tctgccggac
    17941 actgcgactg cgctcccagg tgcccatcat catgatcagc gcgagaagcg acgaggtcga
    18001 ccgggttctc ggtctggagc tgggggcgga cgactatctg tccaaaccgt tcggaatccg
    18061 ggaactggtc gcacggatcc gcgccgtctt ccggcgtgcc ggacccgccg cgaccgggcc
    18121 ggttgcggcc cttccccccg cggccggtcc cgcttcagga ggcgaccgtc ccgatccggt
    18181 ggcccgtgcc cagcggatcg gcccgctggc catcgaccgg cggggccgcc aggtccatct
    18241 gcaccggacc tccgtcgccc tcgcgcccaa ggagttcgat ctgctcgcct acctcgccga
    18301 cgatcccggc gccgtccgca cacgacagca gatcctggac gccgtgtggg aaccgaacta
    18361 cttcggcccc accaagaccc tggacgtgca tgtcgccgca ctgcgccgca agctcggtga
    18421 tcctgcctgg atcgacaaca tccgcggcgt aggattccgg ctcacgccac ccgccggccc
    18481 cgccaccagg caggttgaag aaaatgtccg aggaggtgag gggtgacccg ccgcctcctg
    18541 ctcagctatc tcagtctcac gctgctggtg ctgctgtgcc tggaagtgcc gttcggctac
    18601 gtctacgcgc gtggggagat gtcccggttc accggcaacg ggcagcaggc cgcggtcatg
    18661 ctcgcggagg tgctggagga gaaggtcgag cagcggggca ccgacatccc cgaagtggtg
    18721 gcgagcttcg cgcggcgcac ccgcggccat gtcgtcgtcg tggacaccca aggaaagctg
    18781 ctcaccgact cacgcaacac gatggccacc ggtacggacc tgtccacgca gccggacatc
    18841 gcggccgctc tcgccaacag gtccgattcc ggcacccggc aggatccggc cctggacgag
    18901 gacgtcttct tcgcgacggt gccgggcgcc tcgggcagca cggtccgctg cgtcgtacgg
    18961 gcgtcctttc ccctgacctc ggtggcggcc aaggtgcatg acgcctggct ggcgttggcg
    19021 gccgtggggc tgggggtgct ggcggccgtc gcgctgatag ctctcgcgct ggcccgctgg
    19081 atcacctgcc cggtgcgggc gctggagcac gccacgacac agctcgccga cggcaccctg
    19141 aaggacctgc ccgccaccga cctcgggccg cccgagctgc ggcgcctggc cgccagcttc
    19201 gtccgcaccg cgacccggct gcagcatctg ctcaaggccc agcacgcctt cgcctcggag
    19261 gcgtcccacc agctgaagac cccgctgacc gcactgcggc tgcgactgga gaacttcgag
    19321 ccccatctcg acccacgggc acaacccggc ctcgacgcgg cggtgggcga ggtggagcgg
    19381 ctcagccgca tggtgcacgg tctgctcgcc ctggcccggc tggagaacgc ggcgaccacg
    19441 gcggaggcca ccgacctgga ctccgtcatc gccgaccgcg cggccgtgtg ggccgccttc
    19501 gccggcgagc actacgtgga catggtcgtg gccgggccga ggatcggccg ggtgtgggcc
    19561 atccccgacg ccctggagca gatcatcgac aatctgctct ccaacgcgct gcgggtctca
    19621 ccgccccaca ccacgatcac cctggccacc gcctgggcga acggtgcacc ggcaacggtc
    19681 gaactgcatg tgatcgacca ggggccgggc atgaccgaga accagcggcg acgcgccttc
    19741 gaccgcttct ggcgggcgaa cgacgccgac cacgagggca ccgggctcgg cctgcccatc
    19801 gtgaagcagc tggcccgtgc ctcaggcggc gaggtgtcct tgcgggccgc tcccggcggg
    19861 gggctcgatg ccgtcgtacg cctcaggacc gccgacgcac accgcacggc gcacccgcgc
    19921 cgtgcccgct cggcgatgtg gggcagacag gacggggtgc cgcccgtccc caccggacgc
    19981 ccgcttgccg tatccgactg gcagcagtga ggcggcgaag catgagtgtg ccgctcgccg
    20041 cgctccaggc ccggatgcac cacccccctc cccgcaccac acagacattc acggacacgc
    20101 ccatgacgac gaacaccgat ccctcgtgta ccgcaggggg cgagcaggtc gtaccggccg
    20161 accccgcacc ggagaccatg cgactcctcc tcgtcgagga cgacgaccgg atcgccggcc
    20221 ccatcatgga ggggctggac cgctacggct tcgccgtcga ccatgtgaga tccggggggt
    20281 cggcgctgtc ggcctccccc gccgatctcg tcctgctgga cctcgggctg cccgacatgg
    20341 acggcatcga cgtctgccgg gccctgcgcg cccgctccgc ggtgcccatc atcatgatca
    20401 ccgcacggag cgaggagacg gaccgcgtcg tcggcctgga agtcggggcg gacgactacc
    20461 tgtccaagcc cttcggcgta cgggagctgg tggcccgtat ccgagccgtc acccgccgca
    20521 cccaccccga gcgacacgcc ccaccacaca ccggcaccgc cacgaccgga gtgccccctc
    20581 aaggctccct gcacgcgcaa ctccccgagg ggcgaggcat ccagcacctc ggcccgctga
    20641 ccatcgaccg gcggaccagg ggcgtcacca tcgacagccg cccgctcacc ctcactccga
    20701 aggaattcga tctcctggcc caactggccg gcgatcccgg cgccgtgcac tcccgtcagc
    20761 agatcctcga cgcggtgtgg gacccgaact acttcggccc cactcgcaca ctcgacgtgc
    20821 atgtatcggc gctgcgccgc aagctcggcg acccggcctg gatcgccacg gtccgcggca
    20881 tcggcttccg gctgacggtc cccggggacg gcacgtacgc ctgaacaaac tcgtcgtacc
    20941 actcgtcaac ctttgcgtgc aggaccgttc ctgacgttgc gtcaattcag taatctgaca
    21001 ctgcgtcagt taatcgtgct gtcacacagg agcgggcgga ccgatgcttg gatcaaccca
    21061 cggcaccctc accaccgact cccgccgggc ccgggtcatc gcctgcggtg agccgcgtcc
    21121 cgggcccgca gtccacggcc gggccgccga cgtcgacgac ctcgatgtga gcgggcgacc
    21181 gctgtatgcg gacgtaccgg atctggaccg gttcttccgg cccgggtccg tcgccgtgat
    21241 cggtgcctcg gacaccgagg gacggccgaa caccgggatc acccgacaac tgctggcctg
    21301 ggccgagcgg gtcggggcac gggtgcaccc ggtgcatccc acccggccct cggtcttcgg
    21361 catcccctgc gtcgcctccg tcgccgacct gcccgagcag gtcgacctcg gcgtgctgct
    21421 ggtcgccgat ccgctcccgg tggtcgagga actcgccgag gccaaggtga agttcgccgt
    21481 cgccttcgcc tccgggttcg cggagacggg cgaggagggg gccaaggccc aggagcgtct
    21541 cgccgccgcc gtccggcgct cggggctgag gctgctcggg ccgaacacca acctcaacgc
    21601 gtttgagcgg ttccgccagg acctggaggg accggcgatc gccctgatca cccagtccgg
    21661 gcaccagggc cgaccggtct tcgccctcca ggagctcggc atccggctct cccactgggc
    21721 cccgaccggc aacgaggccg acctggagac cgccgacttc atctcctact tcgccgagcg
    21781 gcccgaggtc ggcgccatcg cctgctacgt ggagggcctc aaggacggcc gcgccttcct
    21841 gctcgccgcc gaccgcgccg cccgccgcaa ggtgccggtc gtcgccgtca aggtggggcg
    21901 cacggaggcc ggggcccgta ccgccgcctc gcacaccggc aagctcaccg gggccgacga
    21961 cgtcgtggac gcggccatgc ggcagttcgg ggtcgtccgg gtcgacgggc tcgacgaact
    22021 ccaggacacc gccgccctgc tggcccgcgc gcgggcaccg ctcgccgacg gggtcgtcgt
    22081 ctactccatc tcgggcggca ccggcgcgca cgtcgccgac ctggccgccg gggccgggct
    22141 cagccttccc gtgctgtccg aggcgcggca ggccgagctg caccagtgga tacccgagta
    22201 cctgagcgtg gccaacccgg tggacaacgg cgggcatccg gtcggcgacc ggcgcggccg
    22261 gaagatcatc gactcgatcc tcgacgaccc ggacgtgggc gtgctgatct gcccggtcac
    22321 cgggcccttc ccaccgctga gcgaccggct cgtacgggac ctggtcgacg cggccgaggc
    22381 gagcgacaag ctggtgtgcg tggtgtgggg ttcgccggtc ggcaccgaag cggcgtaccg
    22441 cgaggtcctg ctcggctcct cccgcgtggc caccttccgc accgtcggca actgcctcac
    22501 cgccgtccgc gcctacctcg accaccaccg cttcgtccgc tcctaccgct cccccttcga
    22561 cgaggcccct cgcaccccct ccccgtcctt caagaaggca cgggccctga tgcagccggg
    22621 gcagcagctg agcgagcacg cggcgaagca gctgctgcgg gcgtacggca tccgggtgcc
    22681 gcgcgagcag ctggtgacca gcgcggcggc cgccgtacgc gccgccgggc aggtcggcta
    22741 ccccgtggtc atgaaggcgt ccggcgcgca gatcgcccac aagaccgagc tgggcctggt
    22801 gaagatcggt ctgacctccg ccagccaggt ccgcgacgcc taccgcgagc tgaccgacat
    22861 cgcccgctac gagggcgtct cgctggatgg cgtcctggtg tgccagatgg tcgagcgggg
    22921 cgtggagatg gtcgtcggcg tcacgcacga cgcgctgttc gggccgacgg tgacggtcgg
    22981 tctcggcggg gtgctggtgg aggtgctgcg ggacgcggcc gtacgcgtgc cgcccttcgg
    23041 cgaggagcag gcccaggaca tgatcgcgga actgcgcggg cgggcactgc tggacggggt
    23101 gcgggggcgg ccacccgccg atgtcgacgg gctcgtcgag gtcgtgctgc gggtgcagcg
    23161 catggccctt gaactcggaa acgaactcgc cgagctcgac atcaacccgc tgatggtgct
    23221 gccccgcggg cagggcgcgg tggcgctgga cgcgctggcg gtgtgccgat gagcggcgac
    23281 gcggtacgcc atgaagccca cggccaggtc tcgtacgtca ccctcgaccg ccccgagacc
    23341 ctgaacgccc tgacgcccga agaccggaac cgcctgatcg gcctgctggg ggaggcgtcg
    23401 gcggacccgg gcgtacgggc tgtggtcctc accggcaccg gccgcggctt ctgcgcgggc
    23461 gcggacctgc gcggcgatgc gcccggcggg gagcgcgtcc cgggcgacgt gtcccgcacg
    23521 ctccgcctcg gcgcgcagcg gctcgtctcc gccgtactgg actgcgagaa gccggtgatc
    23581 gccgccgtga acggcacggc agccggtctc ggcgcccatc tcgcgctcgc ctgcgatctc
    23641 gtgctcgccg ccgagtccgc gcggttcatc gaggtgttcg tgcggcgcgg actcgtgccg
    23701 gacgccggcg gcgcctatct cctgccccgg ctgatcggcc cgcagcgcgc caaggaactg
    23761 atgttcttcg gcgacgcgct ctccgcgccg gacgccgagc ggctcggcct ggtcaaccgg
    23821 gtcgtgccgg acggggagtt ggacaagacg gccagggagt gggcggcacg gctggccgcc
    23881 ggtcccaccc gggcgctcgc cctgaccaag cagatggtga acgcctccct cgacgccggc
    23941 cgcgcctcgg ccttcgccgc cgaggctgcc gcgcaggaga tcaacatgac gacggaggac
    24001 gcccgggagg ggctcagggc cttcgtggaa cgcagaagcc cgaagttccg agggcggtga
    24061 gggtcagccg gccgccgctc gctcgaggat ccacagctcg cccgcgtccg ggtcgccgaa
    24121 gagcacgaac agctcggggg cgtcctcggt gccgctgacc gaccagtggg tgtcctcacc
    24181 gcagtcgccg tcgagccgca ggagcacccc gtcgcgccct gtgtcgtccg ggtcggagtc
    24241 gggctcccag gtgccggaac cgccacacgt gacgaagtcc ttggtggcga actcttcgaa
    24301 ggtggcctcg gtcggcagcc tggtgacctc ggcccgccca ccgggacgca gccgcagctc
    24361 cgccccgctc gggccgcgcc agactccggc gagctgggcg gcggtcagct tcgggggctt
    24421 gtactcaggg gccaggccca tgacggtggc cagaaccccg ccgccgaagg ccaggacgaa
    24481 caggggcacg gaggcgagtg ccgagcgcca ccagacgccc cacggccgcc acgcgcgcgt
    24541 gcggacgtag ccgaccccga gggcgggcag gacacccacg gccgtcaggg acgcgaccgt
    24601 ggtgaccggg gaccagtccc agagcagcgc ggtcggtccg ccccacgcgg ccgccggtgc
    24661 cacgggcgcc gccagatgcc aggcccagcc gggtccgccg aaccggcggg ccgcgaggcg
    24721 ggcgagggcc accgagggca aggtgagggt gaacgcctgc accagcccca ggaacggcag
    24781 cagcagcggc gcgaagagga gcagacagag cacgccgaag gcgccgccgt agccgacgcc
    24841 gtagtcgtcg tggccgaagc tggcgatcca cgccagcaga ccggccgccg gaagctgcgc
    24901 cgcgcagagc gacgcggccg tgttcaggtc gccgaaccac ctggtcatac ggccttctgt
    24961 gcgtgtcgtt ccccacccca tgggggcagc gtacgggcgg ccttcccggc acccgccgta
    25021 ccccttccca tctgacgcat cgtcagcttc aatgggcggt gtgatgggac acgcagggat
    25081 ggcggccgcc gccgtccgct acctcaggtc ggtcgacgcc ccgcccccgg ggcccgtcga
    25141 ggcactgccg cgcccggagc tcaggtgcgt cggggaggac gagcgggcac cggtcgacca
    25201 gggcgagttc cggcgcgtgc tggggcactt cgcgaccggc gtgaccgtgg tcacggcccc
    25261 cgccgtcgac ggcgaggacg gccccgcggg cttcgcctgc cagtccttct cctccctctc
    25321 cctcgacccg ccgctcgtcg tcttcatggt gggccgcacg tcgacgacct ggccgaggat
    25381 cgcccgcacg ggcgtcttct gcgtgaacgt cctcggcgcc caccagggcg agctgtgccg
    25441 cggcttcgcg gtacgcggcg cggacaagtt cgcgggcgtc gcatacggcg cggcccccgt
    25501 ctccggctcc ccgcgcctgg ccggcacact cgcctggatc gactgcaccg tccacgccgt
    25561 gcacaccggc ggcgaccatc tgatcgtcgt gggccgggtg gacgcgctcg gcacggccga
    25621 cgtggacacg gctccggctc ccctgctgtt ccacaagggg cgcttcctct aagccgcgac
    25681 cgccacgggg accgccgccc gccgccggat caccagcgcc atcagggccg ccgccgcgca
    25741 cagcgctccg gaggcgtacc agaccatgtc gtacgacccg aagacgtccc gtgccacacc
    25801 gcccaggaag gcgacgaggg ccgcgccgac ctggtgggag gcgagcaccc agccgaagac
    25861 gatcgcgctg tcctcgccgt actgctcccg gcacagggcc agggtgggcg ggacggtggc
    25921 gacccagtcg aggccgtaga agacgatgaa gaagatcatc ggcgggtgca ccgacggggc
    25981 gaggagcatg ggcaggaaca gaagcgagat cccgcgcagc gcgtagtaca cggcgagcag
    26041 gcggcgcggt tcgaagcggt cggtgaacca gccggaggcg atcgtgccgg ccacgtcgaa
    26101 caccccgatg accgcgagca gcgaggccgc cgccgtgacc ggcatgccgt ggtcgtgggc
    26161 cgcgggcacg aagtgcgtct ggatcaggcc gttggtggag gccccgcaga tcgcgaaggt
    26221 gcccgccagc agccagaagg ggccggtgcg gaccgcggag agaaggaccg tgacggtgcg
    26281 gcgggcggcg ccggtgacgg gctccggctt cggtacgaac tcctcggcgc cgtacggctt
    26341 ctggcccacg tccgccgggt ggtcccgcag cagcagccag acgaacggga cgaccgcgag
    26401 agcggtcagg gagaccgtga cggcggccgg gcgccagtcg tacgtctcga ccatccagga
    26461 cagcagcggc aggaagatca gctgaccgga ggccgaggcc gcggtgagga tgccgctcac
    26521 caggccgcgg cgcgtggtga accagcggtt ggtgaccgtc gcggcgaacg cgagcgccat
    26581 cgagccggag cccaggccga ccagcagacc ccagcacagc atcagctgcc aggccgccgt
    26641 catccacacc gtcaggcccg agccgaccgc gatcacggtc agcgcgacgg cgaccacccg
    26701 gcggatgccg aagcggtcca tcagcgcggc ggcgaagggc gcggtgagcc cgtacagcgc
    26761 gaggttgacg gagaccgcgg cgccgatcgt gccgcgcgac cagccaaact cctggtgcag
    26821 cgggtcgatg agcaggccgg gcagggagcg gaaggcggcc gcgccggtga tcgtgacgaa
    26881 ggtgacggcg gcgacgaacc acgcccggtg gatgcggggc gatcggcggg acttcggttc
    26941 ctgtgcggct gcgatggcct cggttgtctg ggtcacgcca taaagggtcc attccgcgcg
    27001 ccctaccatc gagtggcccg aaggacagca ttcattagga tcgggccaca cgggtcggaa
    27061 tccacgtgtc agaaggtgag cactcccctg gccaccctcc ccgcctccgc gtccgcccgt
    27121 gccttctcga agtcctcgac cgggtacgtc tccgtcacca gttcgtccag cagcagccgc
    27181 ccctgccggt acagctcggc atacagggcg atgtcgcgct gggggcggga ggagccgtaa
    27241 cggcagccca ggatggactt gtccaggtac atggaggaga ccaggaagga cgcctccgcc
    27301 gaggccggcg ggacccccag caggatcgcc tggccgtgcc ggtcgaggag gtcgacggcc
    27361 tggcggatca gctcggtccg gcccacgcac tcgaaggcgt ggtcggcgcc ggtgggcagg
    27421 atgtcccgca cgccctccgc cgaggtcagg aagtccgtgg caccgaactg ccgggccacc
    27481 ggttccttcg cggggttggc gtccaccgcc acgatccgcc gcgcgcccgc gatccgcgcg
    27541 ccctggatga cgttcaggcc gatcccgccg gtcccgatga ccaggacggt gtctccgagg
    27601 cccacccggg cccggttgag cacggctccc acaccggtca gcacaccgca gcccatcagc
    27661 gcggcggacg gcatcgggat gtcctcggga atccgcaccg cctgcacggc cttgacgacc
    27721 gtacgttccg cgaacgcgga gttggaggcg aactgatgga ccggctgccc gcccctgctg
    27781 aacggcttgc ccgggcggcc gatcgccttc cggcacatgg tcgggcgccc ccggtcgcag
    27841 tccgcgcacg caccgcagtt cgcgagggtg gaaagcgcca catggtcccc cggcgacaca
    27901 tgacggacac cctcaccgac cgcctccacc accccggccc cctcgtgccc cagcaccacg
    27961 ggaacgggga agggtatggt cccgtccacc acggacaggt cgctgtggca cagccccgcc
    28021 gccgagatgg agaccagcac ctcaccaggc ccgggatccc gcaccttcag gtcgtcgacg
    28081 acctggacct gcctgccgtc gaacatcaca ccgcgcatca cacgaccccc ttgggttctc
    28141 tcggcagacc gagcacgcgc tcggcgatga tcgtgcgctg tacctggtcc gagccgccgt
    28201 agatggtgtc ggcccgggag aacaggaaca ggtgctgcgc cgcgtcgagt tcgtacggcg
    28261 ccgagggcga ccagtccacg ggccccacgc ccgccgccgc gccgcgcacc cgcaccgcca
    28321 gctccccgag ccgctggtgc cagcccgccc acagcagctt ggccacgctg ggcgtgccgg
    28381 ggtcgcccga accgcccagg gtgcgcaggg cgttccagcg catggcgcgc agctcggccc
    28441 actggcgcac gagccggtcg cggacgaccg gatcggccgc ggcgccggtc tcgacggccg
    28501 tgcgcaggac acgctccagt tcctgggcga acccgatctg ctgggcgagg gtggacacgc
    28561 cccgctcgaa gccgagcagg ctcatcgcga cctgccagcc ctcaccctct ccgcccacga
    28621 cgtgctccac gtgcgcgcgc gcaccgtcga agaagacctc gttgaagtcg ctggtgccgg
    28681 tcatctggcg gatgggccgc acctcgatac ggcccggctg gtccatcggc accagcagga
    28741 agctcagccc gtggtgccgg cgcgagtccg ggtcggtgcg cgcgagtacg aagcaccagt
    28801 cggcctcatg ggcgagcgag gtccagatct tctgaccgct gatccggtag tacggctccc
    28861 gcggttcgcg tacggcggag gtacgcaccc cggccaggtc cgaaccggcg ccgggttcgc
    28921 tgtagccctg gcaccacagt tccgcaccgg cggcgatcgg cggcaggaac cgggacttct
    28981 gggcgtcggt gccatgggcg atgagcgtgg gcgcgagcag attctccccg atgtgcccgg
    29041 accgcggcgg ggcagccgac cgcgcatact cctcggacca gacgacctgc tgggtgaggc
    29101 cgacggtccg gttgccgtaa ccgccctcag gccacccgag cccaatccat ccggccgcgc
    29161 cgagggtacg ttcccaggag cggcggtcct ggactggttc ggcgtgttca gcgagccagg
    29221 cacgcgcctc gatgcggaac gcctcgtcgg ctgccgtaaa cccgaagtcc atggggagcc
    29281 tcccttgtaa tcaccggcca acacccactc cccaaggggc gcggggaact gcgcgaccag
    29341 ccacaaccag cccgcagccg ccaaaccacc acgcaccccg agctattggg cgttgggccg
    29401 agagcctgac tgcgctgccc tctccatcgc ctccagctgg gacagcatcg gcatgggatc
    29461 cacccccacc gacccaggca gaaagtcggc aatccgctcc ggcgtccacg ccccctcgca
    29521 ataggccgaa cgcagttccc tcggctgcgc ccacaccgcg atcttgggcc ccgcaacggt
    29581 gtacacctgc cccgtcaccc ccgcctcgcg ggcccgctcc gagagcagat agaccaccag
    29641 cgcggccaca tcctccggct ccccgatctc cttcagctcc atcggaaccc ccgccgacat
    29701 ccgcgtacga gccacagggg ccaccgcatt cgcgctcacc ccgtacttgt tcaggcccag
    29761 cgcagcgctc cgcaccagcg agatgatccc gcccttcgcc gcgctgtagt tggcctgcga
    29821 caccgagccc tggtggttgc cgctggtgaa gccgatgagg gtgccggact tctgcttgcg
    29881 catgaccgcg gaggccgcgc ggaacaccgt gaaggtgccc ttgaggtggg tggcgacgac
    29941 ggggtcccac tcctcctcag tcatgttgaa cagcatccgc tcgcgcagga tcccggccac
    30001 gcagacggct ccgtcgaggc ggccgtacga cgacagggcg acgtcgacga cccgctgccc
    30061 gcccgccatc gtggagatgt cgtcggccac cgcgaccgcg ctgccgcccg ccgcctctat
    30121 ctccttgacc accgcctcgg cgacctcgct ggtcggtgcg gtgccgtcgg tggacacgcc
    30181 gtagtcgttg acgacgaccc gggcgccctc ggccgcggcc gcgagggcga ccgcccggcc
    30241 gatgccccgt ccggcgcccg tcacggcgac gaccttgcct gccaagaagt tccccacgcc
    30301 cggccccttc ccgcggtttc tgacggaccg ttagatttta tggcgcgtcg gaccgtgaag
    30361 gacaagcccc ggggaggccc cgatgtcact gccggacgag ttccacgaca tcgccaagcg
    30421 tgtgaacaac tgggggcgtt ggggagcggg cgacgagatc ggcaccctga acctgatcac
    30481 cgacgaggtg gtccacgggg cggcggcggc ggtccgtacc ggccgccgtg tgccgctcgc
    30541 gctggcgctg cgcgaggacg gtgtgcagac cgggatgatc ccggggcggg tcaatccgct
    30601 gcacgcgatg gtgcagatca accaggagat cttcgggccg ggcacggtgg cgtgcagcga
    30661 cgacgtggtg acgatgggcc ttcaggcggc gacccactgg gacgcgctga cccatgtctc
    30721 gcactccggg aagctctaca acggccgccc cgcgcacacc gtcaccgcgc acggcggcgc
    30781 cgagttcagc gggatcgaca aggcgcggca catcgtctcg cgcggggtgc tgctcgacgt
    30841 ggcacgcgcg cgtggcgtgg accggctcga cggcgggcac gcggtcaccc cggaggatct
    30901 ggaggcggcc gaggagttcg cgggtacacg ggtgcgggcc ggcgacatcg tgctggtgcg
    30961 gaccggacag gtccaggtgt atctcgccgg ggacaagcac gggtacggct atccgtcgcc
    31021 ggggctttcg gtgcgcaccc cggagtggtt ccacgcgcgc gatgtcgcgg ccgtcgcgaa
    31081 cgacacgctc acctttgaga tatttccgcc cgagatggag aatctgtggc tgcccgtgca
    31141 cgccctggat ctggtggaga tggggatgct ccagggccag aactggaatc tcgaagagtt
    31201 gtccacagcc tgtggagaag aagggcggta cgcgttcctg ctgtcggcga tgcccgagcc
    31261 gttcgtaggg gcgacgggaa ctccggtggc accggtggcc gttctctgag ccaccctccg
    31321 acagccgctc tccgacagcc gctctccgcg cccc
//
