LOCUS       NZ_JAEDWK010000021     20879 bp    DNA     linear   CON 12-MAY-2024
DEFINITION  Stenotrophomonas maltophilia strain 13_FDSW202186518-1r-8 358, whole
            genome shotgun sequence.
ACCESSION   NZ_JAEDWK010000021
VERSION     NZ_JAEDWK010000021.1
KEYWORDS    WGS; RefSeq.
SOURCE      Stenotrophomonas maltophilia
  ORGANISM  Stenotrophomonas maltophilia
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 1126255)
  AUTHORS   Wang,Y. and Wang,L.
  TITLE     The antimicrobial resistance, molecular epidemiology of
            Stenotrophomonas maltophilia isolated from bacteremia patients in a
            tertiary hospital in China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1126255)
  AUTHORS   Wang,Y. and Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2020) Department of Clinical Laboratory, Chinese
            PLA General Hospital, 28 Fuxing Road, Beijing, Beijing 100853, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 20-49x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025461895.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 16:00:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,541
            CDSs (total)                      :: 4,460
            Genes (coding)                    :: 4,414
            CDSs (with protein)               :: 4,414
            Genes (RNA)                       :: 81
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 46
            CDSs (without protein)            :: 46
            Pseudo Genes (ambiguous residues) :: 0 of 46
            Pseudo Genes (frameshifted)       :: 12 of 46
            Pseudo Genes (incomplete)         :: 40 of 46
            Pseudo Genes (internal stop)      :: 6 of 46
            Pseudo Genes (multiple problems)  :: 10 of 46
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:09:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 526208
            Orig. end                         :: 547087
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAEDWK010000021.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20879
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20879
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20879
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10879](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10879)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            504..1991
                     /gene="rng"
                     /locus_tag="JAK51_RS15005"
                     /old_locus_tag="JAK51_15020"
     CDS             504..1991
                     /EC_number="3.1.26.-"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rng"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002802933.1"
                     /locus_tag="JAK51_RS15005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15020"
                     /product="ribonuclease G"
                     /protein_id="WP_049444954.1"
                     /transl_table=11
                     /translation="MSEEILVNVTPRETRVAVIENGMLQELHIERGWRRGVVGNIYKGK
                     VQRVMPGMQAAFVEVGLERAAFLHANDVVRPAPVASADTENTTLPPPSSVPIVELLRDG
                     QDIVVQVVKDPIGTKGARLTTQISIPSRYMVLLPQSKVVGVSARIEDEGERARLKALVT
                     ELSAQHGGYGYIVRTNAEGQPAEAIAEDIAYLSRVWNVVERRGREAPSCSNIYEDLSLP
                     LRSVRDLIRKDVDKVKVDSKETFAQLQAFVAKYMPVLAEKLELYSGDRPIFDMFGVEDE
                     IGRALDKQVPLKSGGYLVIDQTEAMTTIDVNTGSFLGQRNLEETVFRTNLEAAQAVARQ
                     LRLRNLGGIIIIDFIDMDDAEHRRQVLRTLEKALARDHAKTTVYDFSPLGLVEMTRKRT
                     VESLERQLSETCPQCSGRGSIKTTETVTYEIFREITRAVRQFDAARLLVIASTKVVARI
                     TDEESSAVAELEEFLGKSIRFQADEQYLQEQFDVVLL"
     gene            2022..5879
                     /locus_tag="JAK51_RS15010"
                     /old_locus_tag="JAK51_15025"
     CDS             2022..5879
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014647937.1"
                     /locus_tag="JAK51_RS15010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15025"
                     /product="YhdP family protein"
                     /protein_id="WP_262229924.1"
                     /transl_table=11
                     /translation="MSAPPRLRLRRIRRHFIAACAVGLVGLALLVGTLSQLLPLAERHP
                     EKIAAWLSERAGQPVRFEQLQTAWTRRGPLLQLKGLRIGAGQGLAIGEAEVLVSMYSGM
                     LPGRSLTELRLRGLALDLQQGEDGRWSVRGLPKSGTGGDPLDALRRLGELQVIDGRLGV
                     HAPGLGIDTTLPRIDLRLRVNGDRLRVGVRAWAQTDALPLTAVLDVDRARGNGQAWLGA
                     DPVDFHAWSPLLAAGGVRLREGKGELNLWLTLRDFAPVALTTDSDLRDLRIDGAPMPDV
                     ATPQLQLQRLQARLRWQRQADGWALQVPRLRLKTEEGEQQLDGLQLQLGRQLRVSSGEV
                     QAGTALRALALSDRLEPGLRRWLFLSRPQLDVRELQLAGERDGALWAQGELQSLGFASV
                     GHSPGLRGLGGRFEGDADGFSLQLQPQRQLQFDWPTGFGVRHDLHLAGQVVGWRDEGGG
                     WRIGTAAMRVEGTDYAADVRGGVWFQGDGTRPWLQLAAKLDDVPMTAAKRFWIHSRMSK
                     GATDWLDMALAGGQVRNGVGLVSGDLDDWPFDNNDGRFEATGHISNGDIRFQRDWPLMS
                     QVDADIAFIGPGFDMRGRGDLAGVAVQKFEAGIPDFGQQPLYVRADALSEAGKLLSMLR
                     QSPLHKDYGDTLDNLTAAGPAHVTFDLLQPLHLNEGEGHLQGTVDLTGVKLVDKRFQLT
                     FDNMHGQARYSKGGFGAEELAVRHLGQDGRLSLRAGGYVHDSKLAFESQLSATLDAGVL
                     IDRAPEMAWLKPYITGTSPWTIAVNLPKVAPGAPAPPSELRLSSDLVGTRLDLPAPLDK
                     PAAEPLATTVAAQLPMGAGRIDVAFGQRLALAARSHNNQTGVQVTLGSDHVDREPPLSG
                     LTVNGRSPTLDALEWISLARGGGDDDGMPLRAVDVQVGKLMLIGGVFEQTRLKLQPGPQ
                     ALDVRLDGPSLAGHLTVPNAEGGTISGQLDRVHWQSLPTAPGAPAAPARVQAGANDMDP
                     AKLPPFALDIADLQFGKVVLGQAVLRTRPLANGLNVDELRFRAPDQEIDISGRWLGRTG
                     GARTELTAQVRSEDLGGLMQNLDYGGQLRGGSGQAQLQASWSGGPSDFQLATLQGRLDL
                     HARNGQLLELEPGAGRVLGLLSVAQLPRRLMFDFRDFFSKGFAFNQVDGSVQFGQGMAR
                     TDKVLIEGPAANITIRGQADLRNQQFDQTIDVNPRAGNLLTVVGAVAGGPVGAALGAAT
                     NAVLSKPLGEIGARTYKVTGPWKEPKVEVIERSRDKTPPAPTPAPAVPPTVTDLPRSRS
                     R"
     gene            5940..7385
                     /gene="tldD"
                     /locus_tag="JAK51_RS15015"
                     /old_locus_tag="JAK51_15030"
     CDS             5940..7385
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="tldD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007972594.1"
                     /locus_tag="JAK51_RS15015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15030"
                     /product="metalloprotease TldD"
                     /protein_id="WP_262229926.1"
                     /transl_table=11
                     /translation="MTDIALTLAQDRLLRPGGLDTAGLERTFGQLLGPGVDFGDLYFQH
                     ARRESWSVEDGIVKDGAHSIEQGVGVRAISGEKTGFAYSDDIHADALLAAAQSARAISR
                     EGGAQTGRSLLRGNARALYPALDPIDGIGNEAKVEVLKRLDGYLRAADPRVKQVMVSLS
                     GGVDTVLIARSDGVLGADVRPLVRLNVQVIVEHNGRRESGYAGGGGRYGYEELFAGGRP
                     EAFAREALRQALVNLEAVPAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYA
                     GRIGERVAAPGVTIVDDGTLDGRRGSLNIDDEGHPSQCTTLIEDGILVGYMQDSLNARL
                     MGVAPTGNGRRESFAHMTMPRMTNTYMRAGQHDPQEMIRSVKKGLYAVNFGGGQVDITS
                     GKYVFSATEAYLIEDGRITTPVKGATLIGNGPETMQKVRMVGNDLALDEGVGICGKDGQ
                     SVPVGVGQPSLLIEGITVGGTQA"
     gene            complement(7427..8014)
                     /gene="yjgA"
                     /locus_tag="JAK51_RS15020"
                     /old_locus_tag="JAK51_15035"
     CDS             complement(7427..8014)
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yjgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017355121.1"
                     /locus_tag="JAK51_RS15020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15035"
                     /product="ribosome biogenesis factor YjgA"
                     /protein_id="WP_262229927.1"
                     /transl_table=11
                     /translation="MRGRDEETGEFHDKSRSQNRREALDVLALGEKLVSLTPAQLARLP
                     IPEDLLPHIAECKRITAHIAHKRQLAFLAKHMRREEDATLDAIRDALDANSETGRREVA
                     MMHRVEDWRERLLAEGDKALAALLDDYPQADRQQLRTLVRNAQAEKAKNKPPRAYREIY
                     QVLRALMLPAALGLKASAEDADPIETDEADED"
     gene            8082..9449
                     /gene="pmbA"
                     /locus_tag="JAK51_RS15025"
                     /old_locus_tag="JAK51_15040"
     CDS             8082..9449
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="pmbA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019662101.1"
                     /locus_tag="JAK51_RS15025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15040"
                     /product="metalloprotease PmbA"
                     /protein_id="WP_262229929.1"
                     /transl_table=11
                     /translation="MNVIAPEVAVGDDSPARLERLADLSQQLLDRARALGASQAEVSCS
                     EDRGLEVNVRLGEVETVQSTRDRGIAVTVYFGQRKGSASTGDLNEASLAATVEQACAIA
                     RHTEDDPAAGLAEAALMATDFPDLDSWHPWALQADEAVDLALACENAGREADVQIRNSD
                     GASVSSMQSLSVYANSHGFFGRERGTHHSVGCALIAGQGDGMQRDGWYTSALAREDLEE
                     VGLVGRRAAERTVARLQPRSMATGSMPVLFAPEVARSLVGHLLSAVSGGALYRQASFLL
                     DSVGQQLFPGWMQIEELPHLRRGLRSAAFDGDGVATRASALVRDGVLQRYVLGSYSARK
                     LGLQTTANAGGVHNLQLAANAGSLQEIARQMGDGLLVTELMGQGVNGVTGDYSRGAGGF
                     RVENGEIQYPVDGITIAGNLREMFSSIEAVGSDVDPRSHIRTGSILLGRMTIAGND"
     misc_feature    9501..9516
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.39"
                     /tool="antismash"
     gene            9537..9908
                     /locus_tag="JAK51_RS15030"
                     /old_locus_tag="JAK51_15045"
     CDS             9537..9908
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014647933.1"
                     /locus_tag="JAK51_RS15030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15045"
                     /product="DUF4870 domain-containing protein"
                     /protein_id="WP_262229930.1"
                     /transl_table=11
                     /translation="MSEFDNVPPPPATAEAPADQRTMALAAHLLGIFTWFIGPLIIWLI
                     NKDDASKAFVTDQAKEALNFQITITIAMLICIVLTIVIIGGILAPIVGILNLVFCIIAA
                     VKANNGEAYRYPFALRLVK"
     gene            complement(10001..10879)
                     /locus_tag="JAK51_RS15035"
                     /old_locus_tag="JAK51_15050"
     CDS             complement(10001..10879)
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264747.1"
                     /locus_tag="JAK51_RS15035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15050"
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_106468760.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-65, bitscore:
                     217.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEVLFARWRDRIESQLDAALPSPAEAPQRLHQAMRHSVLGGGK
                     RMRPLLVYASGHLFGAQPESLDAAAMSVELIHAYSLVHDDLPAMDDDALRRGKPTTHIA
                     FDEATAILAGDALQTRAFGLLADAPLPATLRVACLQTLAHASGASGMCGGQALDIDATG
                     QQQTLAALTRMHALKTGALIRAAVRMGALCGQAHEPQLAQLDSFADALGLAFQVRDDIL
                     DVEASSEQLGKTAGKDQAQDKSTFPALLGMDGAKAQLHELAARMQAILAGYGEEADALR
                     ALATLAVERDH"
     gene            complement(10869..11129)
                     /locus_tag="JAK51_RS15040"
                     /old_locus_tag="JAK51_15055"
     CDS             complement(10869..11129)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005410522.1"
                     /locus_tag="JAK51_RS15040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15055"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_005410522.1"
                     /transl_table=11
                     /translation="MAKKSPENASPVAQFEQSLESLEQLVEQMETGELSLEASLSAYER
                     GVGLYRQCQQALEQAELRVRLLSDPAQPEASEPFDPPSHDG"
     gene            complement(11166..12452)
                     /gene="tilS"
                     /locus_tag="JAK51_RS15045"
                     /old_locus_tag="JAK51_15060"
     CDS             complement(11166..12452)
                     /EC_number="6.3.4.19"
                     /GO_function="GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tilS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005418067.1"
                     /locus_tag="JAK51_RS15045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15060"
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="WP_262229931.1"
                     /transl_table=11
                     /translation="MTAFPALVPLDAPLLVGYSGGVDSTVLLHWLWRCAQASGTALRAV
                     HVHHGLQPDADDWVLHCQQQCEAWGIELAVHRVQVDNRAGLGLEGAARQARRDAFAAEL
                     RDGETLALAQHQDDQAETFLLRALRGSGVDGLAAMSAHSRLGEHQLWRPLLSTPRDALL
                     HYARQHALQWIEDPSNAEDHADRNFLRLQVLPLLRQRWPHAATALAGSATHCRQTRELL
                     DEEDAELIAHLEVAPRVLSLELLRQVSPGRAARVLRAWVLGHAAAPLPATVLKQALDEL
                     LPADNDRQARVSWHDHAIQQWRDHAYLLPAQLPALPLEWQVEWDGRAPLPLPDGGQLRL
                     QGTPAFERPLQVRARVGGERILLPGRQHSHALKDCLQREHLAPWRRAQLPLIFDGPQLL
                     AAADVVIAAPLQAWLQAHDAQLQWRPGGW"
     misc_feature    12906..12916
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(12987..13532)
                     /locus_tag="JAK51_RS15050"
                     /old_locus_tag="JAK51_15065"
     CDS             complement(12987..13532)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660636.1"
                     /locus_tag="JAK51_RS15050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15065"
                     /product="WG repeat-containing protein"
                     /protein_id="WP_262229932.1"
                     /transl_table=11
                     /translation="MIARQARPAPASGRFARSLVLLGVLVSANAAAQAPACKLLTDEHG
                     LWPLPNCEVVDHRPKIGADTLKDLNYDDHGLAVVYADQGFHYVDGTGRSLPVLTWDNGP
                     ETPQEGLLRARVGNRVGYFDLKFRQVVPGTFDFGWPFQDGVAEVCNGCRRGTPDADGHT
                     PMEGGERFRIDRSGRRVK"
     gene            complement(13529..15235)
                     /locus_tag="JAK51_RS15055"
                     /old_locus_tag="JAK51_15070"
     CDS             complement(13529..15235)
                     /EC_number="3.1.3.1"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660635.1"
                     /locus_tag="JAK51_RS15055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15070"
                     /product="alkaline phosphatase"
                     /protein_id="WP_106468757.1"
                     /transl_table=11
                     /translation="MRRSVSLLAACATTLLLGACASTAPASAPAGLKVAVDPVAHPAGE
                     TPQWWYRSGAAQAAANGAMSGKAKNVILFLGDGMSLTTVAASRIYEGQQKGGSGEENLL
                     SWERFPATAFSKTYNTDSQTPDSAGTMTAITTGVKTHMGAIGVSAGSRTDCADSLSKGL
                     LTWLQLADSAGLATGVVSTARLTHATPAATYAHSPERNWENDTDLTEAAKAAGCKDIAQ
                     QLLSTSRYGRGPLVALGGGRGEFTTVEERDPEYDDKVGQRLDGRSLVQEWQQAHPQGAY
                     VWNSKQLAAAANAPAILGLFEPDHMRYEYERPQDPGGEPSLAELTAAAIKNLAKHQEGY
                     VLMIEGARIDHANHSGNAYRALTETVALSDAVRVANELTSADDTLIIVTADHSHTLNFV
                     GYPARGNPILGKVKDKGGEDGAGKLDYALDGSGQPYTTLTYANGPGHTGASNQQPAGTK
                     RYPHNPSSFEPANGRPNLREVDTEHPDYMQEALVPMKSESHGGEDVGIWARGPGSKAIR
                     GTLEQNAIYHMIVQATPALRERLCQAGTCDDKGVPVQLPAPTAFERKAEAK"
     gene            15390..16724
                     /locus_tag="JAK51_RS15060"
                     /old_locus_tag="JAK51_15075"
     CDS             15390..16724
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1212:
                     sodium:dicarboxylate symporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014038012.1"
                     /locus_tag="JAK51_RS15060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15075"
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="WP_005410518.1"
                     /transl_table=11
                     /translation="MKLVSAWLRIPFWQRVVGGFVLGALAGWALGPAAETWFGPLGELY
                     VTLIKMIAVPLVFFAVINAISSLHGQKSVAALSGRTFLWFVITAALAVCVGLGVGTVLQ
                     PGAGGLQLTMASNYVPREVPSVVQVLLDVVPANVFYALSGIGTKVNAAGETVLAAGRGS
                     ILPVIFFAGLVGFAIVKLGEKVTEARKLVGQMSDIMIQVTRFVLEVTPIGTFGLIAGLV
                     GSYGFEKLLPLGHFVLALYVACALHIVVVYSALLLAHGLNPLKFFRGAAPGMQVAFVSS
                     SSFAAMPVALRSITHNLGVNKDYGSFAVPLGASIKMDGCGAIYPALCAVFIAQYSGVPL
                     TPEQYVVVLIASVLGSFGTAGVPGTAVIMATVVLSAANLPLETIGYLYAIDRILDMMRT
                     MTNVTGQMLVPVIVAKETGLLDQAVYDNPSSNVGVDDPDPTPPRG"
     gene            complement(16952..17659)
                     /locus_tag="JAK51_RS15065"
                     /old_locus_tag="JAK51_15080"
     CDS             complement(16952..17659)
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003475603.1"
                     /locus_tag="JAK51_RS15065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15080"
                     /product="C40 family peptidase"
                     /protein_id="WP_262230268.1"
                     /transl_table=11
                     /translation="MLGLALCLTSLPAWSQTAPNRSDVTPAQVAESTARPAAKAEAAAP
                     QRSRVDAAASATLAALLPHLAANDTIPLMDRSAVVAGDLSRLLANYDTSSAANGSVVGT
                     AADNGKVQSLLRRAMTLLGTPYRWGGSNPDSGFDCSGLVGYVFRSALGIELPRVSREMA
                     HDDNAELINDRTALAAGDLVFFGRKGRVDHVGIYVGDGRFLHAPSSGKDVRVDTLLSGY
                     WGNKFMQARRVDL"
     misc_feature    17721..17736
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    complement(17739..17748)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.63"
                     /tool="antismash"
     misc_feature    17816..17831
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            complement(17857..18435)
                     /locus_tag="JAK51_RS15070"
                     /old_locus_tag="JAK51_15085"
     CDS             complement(17857..18435)
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005414114.1"
                     /locus_tag="JAK51_RS15070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15085"
                     /product="C40 family peptidase"
                     /protein_id="WP_065428014.1"
                     /transl_table=11
                     /translation="MTANPKVAHYPEIMHITPVSSGLRRLLAPALLLALPVLMTACGGG
                     KATRPAPPPPTANWPKTVPDNPEAANSVLMRAISLVGTPYRYGGNTPDSGFDCSGLVAY
                     VYREMLDLKLPRTSRDLAAVQGPKIDPQRLATGDLVFFGSRGSVTHVGIYVGEGRFVHA
                     PSTGGTVRLDSLSGPYWKDHYTGAKRVLR"
     gene            18509..18991
                     /locus_tag="JAK51_RS15075"
                     /old_locus_tag="JAK51_15090"
     CDS             18509..18991
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005418041.1"
                     /locus_tag="JAK51_RS15075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15090"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_005418041.1"
                     /transl_table=11
                     /translation="MKIEKDRVVRFHYTVSEVGQEPIESSKDRGEPLAILIGHGNIIPG
                     LENAMMDKEAGATFNVDVKAADAYGERREGLSQRVPKKHFGNTKLAPGQQVVLQTNFGP
                     RAVTVQKVGMSVVDVDLNHPMAGKDLHFDVEIVDVREAGKEEIDHGHVHGDGGHQH"
     gene            19091..20335
                     /locus_tag="JAK51_RS15080"
                     /old_locus_tag="JAK51_15095"
     CDS             19091..20335
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005410514.1"
                     /locus_tag="JAK51_RS15080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JAK51_15095"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_262229933.1"
                     /transl_table=11
                     /translation="MADLPDGRPVNAASPSLQPVASGERIAVLDVLRGAALLGILLMNI
                     EAFSGPLDLAFTGIDVHWRGIDYWADAFVYVFVQGKFFTLFSLLFGAGFAVMAQRAEVA
                     GRDFTPFYLRRSAALLLIGLCHALLVWSGDILVMYALISLPLLACREAPRSWVPWMGLM
                     VYLGGVAMMLLVGAMVSMASAEDVQGMLAEAQRSIELQRQVYGQGSWAQVNVQRLSEFG
                     TSMGALLITGPEVLGMFLIGSWFAGSGALAAPERFPRLYASLRWIALPLGLLVTLIGVA
                     WKPYLAPGAYNLPVTAAMGLVTIGGLPMCLGYLAWIVHWRTRLAWLAPVGRMALTHYLG
                     QSLLCTWLFYHYGLGGFELMPRSVQLLFALLLFAVQVALSHVWLRRFRFGPMEWLWRAM
                     TYRQWPPMRREAGQG"
     misc_feature    20761..20775
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.2"
                     /tool="antismash"
ORIGIN
        1 cgcgcccgct gaaagcgccg aacagtatgt aggccgtgtc gccgccgaca aggcgcgcgc
       61 cgggctggcc cgggtgctgg ccgatgaccc gcaggcgcgg gtgctcggct cggataccga
      121 ggtggtgctg gacggtgaag tgttcggcaa gccggccgat gccgccgacg cgcgggtgat
      181 gctggcccgg ctggccggcc gcacccacca ggtgatgact gcggtggtgg tggtctctgc
      241 ggaggggctg gacagcgagc tggtcatttc cgaagtgacc ttcgcgccga tcagtgccgc
      301 ggacatcgcc acctacgtgg ctaccggcga accgctggac aaggccgggg cctacgccat
      361 ccagggcggg gccgagcgct ggatcgaaca tctttcaggc agctactccg gtgtgatggg
      421 actgccgctg ctgcacaccg atcgtctgct ggcgcgctgc ggcgtgccgg cacccactgc
      481 tgatgccgcc agggaggctg ccgatgtctg aggaaatcct ggtcaatgtg accccgcgcg
      541 agacccgggt cgccgtgatc gaaaacggca tgctgcagga gctgcacatc gagcgcgggt
      601 ggcgccgggg tgtggtcggc aacatctaca agggcaaggt gcagcgcgtg atgcctggca
      661 tgcaggcggc cttcgtcgag gtcgggctgg agcgcgccgc gttcctgcac gccaacgacg
      721 tggtgcgccc ggcgccggtg gccagtgcgg acaccgagaa caccacgctg ccgccgccgt
      781 ccagcgtgcc gatcgtcgag ctgctgcgcg acggccagga catcgtggtg caggtggtga
      841 aggacccgat cgggaccaag ggcgcacgcc tgaccaccca gatcagcatt ccctcgcgtt
      901 acatggtgct gctgccgcag tccaaggtgg tgggcgtgtc ggcgcgcatc gaggatgaag
      961 gcgagcgggc gcggctgaag gcgctggtga ccgaactgtc ggcccagcat ggcggctacg
     1021 gctacatcgt gcgtaccaat gccgaagggc agccggccga ggccattgcc gaggacatcg
     1081 cctacctgtc gcgggtctgg aacgtggttg agcgccgtgg ccgcgaagcg ccctcgtgca
     1141 gcaacatcta tgaggacctg agcctgccgc tgcgttcggt gcgcgacctg atccgcaagg
     1201 acgtggacaa ggtgaaggtg gactccaagg aaaccttcgc gcagctgcag gccttcgtgg
     1261 ccaagtacat gccggtgctg gccgagaagc tggaactgta ttcgggtgac cgaccgatct
     1321 tcgacatgtt cggcgtggaa gacgagatcg gccgcgcgct ggacaagcag gtgccgctga
     1381 aatccggcgg ctacctggtg atcgaccaga ccgaggcgat gaccaccatc gatgtgaaca
     1441 ccggttcgtt cctcggccag cgcaacctgg aagagacggt gttccgcacc aacctggaag
     1501 ccgcgcaggc agtggcgcgg cagctgcggc tgcgcaacct gggcggcatc atcatcatcg
     1561 atttcatcga catggacgac gccgagcatc gccgccaggt gctgcgcacc ctggaaaagg
     1621 cgctggcccg tgaccatgcc aagaccacgg tgtatgactt ctcgccgctg ggcctggtgg
     1681 agatgacccg caagcgcacg gtggaaagcc tggagcgcca gctgtcggaa acctgcccgc
     1741 agtgcagcgg ccgtggcagc atcaagacca ccgagacggt gacctacgag attttccgcg
     1801 agatcacccg cgcggtgcgc cagttcgatg cggcgcgcct gctggtgatc gcttcgacca
     1861 aggtcgttgc gcgcattacc gacgaggagt cttcggcggt ggccgaactg gaagaattcc
     1921 tcggcaagag catccgcttc caggcggacg agcagtacct gcaggagcaa ttcgatgtcg
     1981 ttctgctctg atcctcgccg gctgcaggcc ggcggtggcc gatgagcgcg ccgccgcgcc
     2041 tgcgactgcg aaggatccgc cgtcacttca ttgccgcctg cgcggtgggc ctggtcgggc
     2101 ttgcactgct ggtgggcacg ctcagccagc tgctgccgct ggccgagcgt catcctgaaa
     2161 agattgccgc ctggctgagc gagcgtgccg gccagccggt gcgtttcgag cagttgcaga
     2221 ctgcctggac ccgtcgcggt ccgctgttgc agctgaaggg cctgcgcatc ggcgccggcc
     2281 agggcctggc gatcggcgag gccgaagtgc tggtgtcgat gtacagcggg atgctgcctg
     2341 gccgctcgct gaccgagttg cgcctgcgtg gcctggcgct ggacctgcag cagggcgagg
     2401 acggccgctg gtcggtgcgc ggcctaccga agtcaggcac gggcggtgac ccgctggacg
     2461 cgctgcgccg gctgggcgag ctgcaggtga tcgatggccg gctgggcgtg catgcaccgg
     2521 gattgggtat cgacactacc ttgccgcgta tcgatctgcg cctgcgcgtc aatggcgacc
     2581 gcctgcgtgt gggtgtgcgt gcgtgggcgc agaccgatgc gctgccgctg accgcagtgc
     2641 tggatgtgga ccgcgcgcgc ggcaacggcc aggcctggct gggtgccgat cctgttgatt
     2701 tccacgcctg gtcgccgctg ctggcggccg gtggcgtgcg cctgcgcgaa ggcaagggtg
     2761 agctgaacct gtggctgacc ctgcgcgact tcgcgccggt ggcgctgacc accgattcgg
     2821 acctgcgtga cctgcgcatc gacggtgcac cgatgcccga cgtggcgacg ccgcagttgc
     2881 agctgcagcg cttgcaggcg cgcctgcgct ggcagcgcca ggccgatggt tgggcgctgc
     2941 aggtgccgcg cctgcgcctg aaaaccgaag agggcgagca gcagctcgat ggcctgcagc
     3001 tgcagctcgg caggcagctg cgggtgagtt ccggcgaagt gcaggccggt accgcgctgc
     3061 gtgcgctggc cctgagcgat cgtcttgaac cgggcctgcg tcgctggctg ttcctgtcca
     3121 ggccgcagct ggacgtgcgc gagttgcagt tggccggcga acgcgatggc gcgctgtggg
     3181 cgcagggaga gctgcagtcg ctgggtttcg ccagcgtcgg gcattccccg ggcctgcgtg
     3241 gcctgggggg acgtttcgag ggcgatgccg atggcttcag cctgcagctg cagccgcaac
     3301 ggcagctgca gttcgattgg ccgaccggct ttggtgtgcg ccatgacctg cacctggcag
     3361 gacaggtggt gggatggcgc gacgagggcg gtggctggcg tatcggcact gcggcgatgc
     3421 gcgtggaagg caccgactac gcggccgacg tgcgcggtgg tgtctggttc cagggcgacg
     3481 gcacgcggcc ctggctgcag ctggcggcca agctggacga tgtgccgatg accgcagcca
     3541 agcgcttctg gatccactcc aggatgagca agggcgccac cgactggttg gacatggcgc
     3601 tggccggcgg ccaggtgcgc aatggcgtcg gcctggtcag cggtgacctg gacgactggc
     3661 cgttcgacaa caacgatggc cgcttcgagg ccaccggcca catcagcaac ggcgacatcc
     3721 gcttccagcg cgactggccg ctgatgagcc aggtcgatgc cgatatcgcc ttcatcggcc
     3781 ccggcttcga catgcgtgga cgcggcgacc tggccggtgt agcggtgcag aagttcgaag
     3841 cgggcattcc ggatttcggc cagcagccgc tgtacgtgcg tgccgatgcc ctcagcgagg
     3901 cgggcaagct gctgtcgatg ctgcggcaga gcccattgca caaggattat ggcgacaccc
     3961 tcgacaacct caccgctgcg ggaccggcgc atgtaacctt cgatctgctg cagccgctgc
     4021 acctgaatga aggcgagggc cacctgcagg gtacggtcga cctgaccggt gtgaagctgg
     4081 tcgacaagcg gttccagttg accttcgaca acatgcatgg gcaggcgcgc tacagcaaag
     4141 gcggtttcgg cgccgaggaa ctggcggtgc gtcacctcgg ccaggacggc cgcctgagcc
     4201 tgcgtgccgg cggttacgtg cacgacagca agctggcctt tgaatcgcag ctgtcggcca
     4261 cgcttgatgc tggcgtgctg atcgaccgcg cgccggaaat ggcgtggctg aagccctaca
     4321 tcaccggaac ctcgccgtgg accatcgcgg tcaacctgcc caaggtcgcg ccgggggcgc
     4381 ctgcgccgcc cagcgagctg cggttgagct ccgatctggt cgggacccgg ctggacctgc
     4441 cggcgccgct ggacaaaccg gctgccgagc cgttggcgac cactgtggct gcacagctcc
     4501 cgatgggggc cggccgcatc gacgtggcct tcggccagcg cctggcgctg gccgcgcgca
     4561 gccacaacaa ccagaccggc gtgcaggtca cgctcggcag cgaccacgtt gaccgtgagc
     4621 cgccactgag cgggctgacc gtcaacggtc gcagcccgac cctggatgcg ctggagtgga
     4681 tcagcctggc gcgtggaggc ggtgacgacg acggaatgcc gctgcgcgcc gtggacgtgc
     4741 aggtcggcaa attgatgctg atcggcggcg tcttcgagca gacacggctg aaactgcagc
     4801 cgggcccgca ggcgctggat gtgcgcctgg atgggccgtc gctggcgggc cacctgaccg
     4861 ttcccaatgc cgagggcggc accatcagcg gccagctcga ccgtgtgcac tggcagtcgc
     4921 tgccgaccgc accgggcgca ccggctgcgc cggcgcgggt acaggccggc gccaacgaca
     4981 tggatccggc aaagctgccg ccattcgcgc tggacattgc cgatctgcag ttcggcaagg
     5041 tcgtactcgg ccaggcggtg ctgcgtacgc ggccgctggc caatggcctg aacgtggacg
     5101 agctgcgctt ccgtgcgccc gaccaggaga ttgacatcag cggtcgctgg ctgggccgta
     5161 ccggcggtgc ccgcaccgag ctgaccgcac aggtgcgcag tgaagacctg ggcggcctga
     5221 tgcagaacct ggactacggt ggccagctgc gcggcggctc cggtcaggcc cagctgcagg
     5281 cctcgtggag cggcggtccc tcggacttcc agctggccac tctgcagggc cggctcgacc
     5341 tgcacgcgcg caacggccag ttgctggagc tggagcccgg cgcaggccgc gtgctcggcc
     5401 tgctcagtgt cgcgcagctg ccgcggcgcc tgatgttcga cttccgcgat ttcttctcca
     5461 agggcttcgc gttcaaccag gtcgatggca gcgtgcagtt cggccagggc atggcccgta
     5521 ccgacaaagt gctgatcgag ggtccggcgg cgaacatcac catccgcggc caggccgacc
     5581 tgcgcaacca gcagttcgac cagaccatcg acgtcaaccc gcgcgccggc aacctgctga
     5641 ccgtggtcgg cgcggtggcg ggtggcccgg tgggtgcggc actcggcgcc gccaccaatg
     5701 cggtattgtc caagccactg ggcgaaatcg gcgcccgtac ctacaaggtg accggtccat
     5761 ggaaggagcc gaaggtggaa gtgatcgaac gcagccgcga caaaacgccg cccgcaccca
     5821 caccggcacc ggcggttccg ccgacggtga ccgacctgcc acgctcgcgt tcacgctgag
     5881 cctggtgttc ccgttcacgg ggcttgcctg agcgcccccg catccccaga tcgaggacca
     5941 tgactgatat cgccctgaca cttgcccaag accgcctgtt gcgccctggt ggcctggata
     6001 ccgctggcct tgagcgcacc ttcgggcagt tgctcggccc cggtgtggac tttggtgacc
     6061 tttacttcca gcacgcccgc cgcgagagct ggagcgtgga ggatggcatc gtcaaggacg
     6121 gtgcccattc catcgagcag ggcgtgggtg tgcgcgcgat ttccggcgag aagaccggct
     6181 tcgcctactc cgatgacatc catgcagacg cgctgctggc tgcggcgcag tcggcacgtg
     6241 cgatttcgcg cgaaggtggc gcccagaccg ggcgttcgct gctgcgcggc aatgcgcgcg
     6301 cgctgtatcc ggcgctggac ccgatcgacg gcatcggcaa tgaggccaag gtcgaggtgc
     6361 tcaagcgcct ggacggctac ctgcgtgccg ccgacccgcg cgtgaagcag gtgatggtca
     6421 gcctgtccgg tggcgtcgat acggtgctga tcgctcgcag cgacggcgtg ctgggcgccg
     6481 acgtgcgccc gctggtgcgc ctgaacgtgc aggtgatcgt cgagcacaac ggccgtcgcg
     6541 agtccggcta tgccggtggc ggtggccgct atggctacga ggagctgttc gccggcggcc
     6601 gcccggaagc cttcgcccgc gaggcgctgc gccaggcgtt ggtgaacctt gaagcggtac
     6661 cggctccggc cggcgtgatg ccggtggtac tgggtccggg ctggcccggc gtgctgctgc
     6721 atgaagcggt cggccatggc ctggaaggcg acttcaaccg caagggcacc agcgtctacg
     6781 cgggccgcat cggcgagcgc gttgccgccc cgggcgtgac gatcgtcgat gacggcacgc
     6841 tggacggacg ccgtggttca ttgaacatcg acgacgaggg tcatcccagc cagtgcacca
     6901 cgctgatcga ggacggcatc ctggtcggct acatgcagga cagcctcaac gcgcgcctga
     6961 tgggcgtggc gccgaccggc aatggccgcc gcgaatcatt cgcgcacatg accatgccgc
     7021 gcatgaccaa cacctacatg cgtgccggcc agcacgaccc gcaggagatg atccgttctg
     7081 tgaagaaggg cctgtacgcg gtcaactttg gcggcggcca ggtcgacatc accagcggca
     7141 agtacgtgtt ctcggccacc gaggcctacc tgatcgagga tgggcgcatc accacgccgg
     7201 tgaagggcgc gaccctgatc ggcaacggcc cggaaaccat gcagaaggtg cgcatggtcg
     7261 gcaacgacct ggccctggac gagggtgtgg gcatctgcgg caaggatggg cagagcgtgc
     7321 ccgtgggtgt cggccagccc tcgctgttga tcgagggcat caccgtcggc ggtacccagg
     7381 cctgagccgg gcgatggcca gcgccaccgc cccgaccgac ggggactcag tcctcgtcgg
     7441 cttcgtcggt ctcgatgggg tcggcgtctt cggcgctggc cttcaggccc agcgccgccg
     7501 gaagcatcag cgcgcgcagc acctggtaga tctcgcggta ggcgcgcggc ggcttgttct
     7561 tcgccttctc ggcctgcgcg ttgcgcacca gcgtgcgcag ctgctggcgg tcggcctgcg
     7621 ggtagtcgtc cagcagggcg gccagcgcct tgtcgccttc ggccagcagg cgctcgcgcc
     7681 agtcttccac gcggtgcatc atcgccactt cgcggcggcc ggtttcgctg ttggcgtcca
     7741 gcgcatcgcg gatcgcatcc agcgtggcgt cttcttcgcg gcgcatgtgc ttggccagga
     7801 acgccagctg gcgcttgtgg gcgatgtggg cggtgatgcg cttgcactcg gcgatatgcg
     7861 gcagcaggtc ttccggaatc ggcaggcgcg ccagctgggc cggggtcaac gacaccagct
     7921 tctcgcccag ggccaggacg tcgagcgcct cgcgccggtt ctggctgcgg ctcttgtcgt
     7981 ggaattcacc ggtttcttcg tcgcgtccgc gcatcgttcc tacctgatct caaaaaagtc
     8041 gcccggcgtg atgccgggcc caacccgtac aggataaagc attgaacgtg atcgcccctg
     8101 aagtggccgt cggcgacgac agcccggccc ggctggaacg gctggccgac ctctcccagc
     8161 agctgctcga ccgtgcccgt gcgctgggcg ccagccaggc cgaggtcagc tgcagcgagg
     8221 accgtggcct ggaggtcaat gtccgccttg gcgaggttga gaccgtgcag tccacccgtg
     8281 accgcggtat cgccgtcacc gtctattttg gccaacgcaa gggcagcgcc agcaccggtg
     8341 acctgaacga ggccagcctt gccgccacag tcgagcaggc ctgcgcgatt gcccgccata
     8401 ccgaggacga cccggccgcc ggcctggccg aggcggcgct gatggcgacc gacttccccg
     8461 acctggacag ctggcacccc tgggcgctgc aggccgacga ggcggtggat ctcgccctgg
     8521 cctgtgaaaa cgccggccgc gaggccgatg tgcagatccg caattccgac ggcgcctcgg
     8581 tgtcgagcat gcagagcctg tcggtgtacg ccaattcgca tggctttttc ggccgtgagc
     8641 gtggcaccca tcattcggtg ggctgtgcgc tgattgccgg ccagggtgat ggcatgcagc
     8701 gcgatggctg gtacaccagc gcgttggccc gtgaggatct ggaggaggtg ggcctggtcg
     8761 gtcgtcgtgc cgccgagcgc accgtcgccc gcctgcagcc tcgttcgatg gccaccggca
     8821 gcatgccggt gctgttcgcc ccggaagtgg cacgcagcct ggtcggtcac ctgctgtcgg
     8881 cggtgtccgg cggtgccctg taccgccagg ccagcttcct gctggacagc gttggccagc
     8941 agctgttccc gggctggatg cagatcgagg agttgcccca cctgcgccgt ggcctgcgct
     9001 cggccgcctt cgacggtgac ggcgtggcca cccgtgcttc ggcgctggtc cgtgacggtg
     9061 tgctgcagcg ctacgtactg ggcagctatt cggcacgcaa gctgggcctg cagaccaccg
     9121 ccaatgcggg cggcgtgcac aacctgcagc tggccgccaa cgcgggctcc ctgcaggaga
     9181 tcgcgcggca gatgggcgat ggcctgctgg tgaccgagct gatggggcag ggcgtgaacg
     9241 gggtgaccgg cgactactcg cgcggtgccg gtggcttccg cgtcgagaac ggcgagatcc
     9301 agtacccggt ggacggcatc accatcgccg gcaatctgcg cgagatgttc agcagtatcg
     9361 aggcggttgg cagcgacgtc gatccgcgct cgcacatccg gaccggctcg atcctgctgg
     9421 ggcggatgac catcgccggt aatgattgat ggtattgatg gcgtaagcta tgcccgcctg
     9481 acgcaaccag ctgggtgctg gttggtcaag accacccaat gaaaaggagt tttgtcgtga
     9541 gcgaattcga taacgtcccg ccgccgccgg ccaccgccga ggccccggcc gaccagcgca
     9601 ccatggcgct ggctgcgcac ctgctgggca tcttcacctg gttcatcggt ccgctgatca
     9661 tctggttgat caacaaggac gacgccagca aggctttcgt gaccgaccag gccaaggaag
     9721 cgctgaactt ccagatcacc atcaccatcg cgatgctgat ctgcatcgtg ctgaccatcg
     9781 tgatcatcgg cggcatcctg gccccgatcg tcggcatcct gaacttggtg ttctgcatca
     9841 ttgcagcggt caaggccaac aacggtgaag cgtaccgcta cccgttcgcg ctgcgcctgg
     9901 tcaagtaaaa ccagctgcat gcggaactga aaacgcccgg catcgccggg cgttttcatg
     9961 tgcggggagc ggcgggcggt gcccggcgag cgcgcagcga tcaatgatcg cgttcgaccg
    10021 ccagcgtcgc cagtgcgcgc agcgcatcgg cctcttcgcc gtatccagcc aggatcgcct
    10081 gcatgcgcgc tgcgagctcg tgcagctggg cctttgcgcc gtccatgcca agcagggcgg
    10141 ggaaggtgct cttgtcctgc gcctggtcct tgccggcggt cttgcccagc tgctcggaac
    10201 tggcctcgac atcgaggatg tcgtcgcgta cctggaaggc caggccgagc gcatcggcga
    10261 agctgtccag ctgggccagc tgcggttcgt gggcctggcc gcacagcgcg cccatgcgca
    10321 ccgctgcgcg gatcagcgcg cccgtcttca gcgcgtgcat gcgggtcagc gcggccaacg
    10381 tctgctgctg gccggtggca tcgatatcca gcgcctggcc gccgcacatg ccggacgcgc
    10441 cggaggcgtg ggccagggtc tgcaggcagg ccacgcgcag cgtggccggc agcggtgcat
    10501 cggccagcag gccgaaggca cgggtctgca gggcgtcgcc ggcgaggatc gcggtggctt
    10561 cgtcgaaggc gatgtgcgtg gtcggcttgc cacggcgcag cgcgtcatca tccatcgccg
    10621 gcaggtcgtc atgcaccagc gagtaggcgt ggatgagctc gacggacatg gccgccgcat
    10681 ccaggctttc cggctgcgca ccgaacaggt ggccactggc gtagaccagc agcgggcgca
    10741 tgcgcttgcc accgcccagc accgaatggc gcatggcctg gtgcaggcgc tgcggtgctt
    10801 cggcaggcga gggcagagcg gcgtcgagct ggctttcgat acggtcgcgc cagcgcgcga
    10861 acagaacctc agccgtcatg gctgggcgga tcgaagggct cggaggcttc cggctgcgcc
    10921 ggatcgctga gcaggcgcac gcgtagttcg gcctgctcca gcgcctgctg gcactggcga
    10981 tacagaccga cgccacgttc gtaagcactg agtgaggctt ccaggctcag ctcgccggtt
    11041 tccatctgct ccaccagctg ttccagcgat tcgagcgact gctcgaactg ggcaaccggg
    11101 gaggcgtttt cgggggactt cttggccatg tggcaagtgt ggacgggccg cgcgcggggg
    11161 tcaattcacc agccgccggg acgccactgc agctgagcat catgggcctg caaccaggcc
    11221 tgcagagggg ccgcgatgac cacgtcggcg gcggccagca actgcgggcc atcaaagatc
    11281 agcggcagct gcgcgcgtcg ccacggggcg aggtgttcgc gttgcaggca gtccttcaac
    11341 gcgtgcgaat gctggcgacc gggcagcaga atgcgctcac cgcccacgcg tgcacggacc
    11401 tgcagcgggc gttcgaaggc cggggtgccc tgcaggcgca gctgtccgcc atcgggcagc
    11461 ggcagcggtg cgcgtccatc ccattcgacc tgccactcga ggggaagcgc aggcagctgg
    11521 gcaggcagca ggtaggcgtg gtcgcgccac tgctggatcg cgtgatcgtg ccagctcaca
    11581 cgggcctgac gatcgttgtc ggccggcagc agttcgtcca gcgcctgttt cagcaccgtg
    11641 gccggcaacg gtgctgcagc atggcccagc acccaggcgc gcagcacgcg tgcggcgcgg
    11701 cccggtgaca cctggcgcag aagttccaat gacagcacgc gcggtgccac ttccagatgc
    11761 gcgatcagtt cggcgtcttc ctcgtccagc agttcgcggg tctgccggca atgcgtcgcg
    11821 ctgccggcca atgccgtcgc cgcgtgtggc cagcgctggc gcagcaacgg caacacctgc
    11881 aggcgcagga agttgcgatc agcgtggtct tccgcgttgc tggggtcttc gatccattga
    11941 agcgcgtgct gccgggcgta gtggagcagc gcgtcgcgcg gcgtcgacag cagtggtcgc
    12001 cacagctgat gttcgccaag gcggctgtgt gcggacatcg ctgcaaggcc gtcgacgcct
    12061 gaaccgcgca gcgcgcgcag caggaaggtc tcggcctggt cgtcctgatg ctgcgccagt
    12121 gccagcgttt cgccgtcgcg cagttcggcc gcgaacgcgt cgcgtcgcgc ctgccgcgcc
    12181 gcgccttcaa ggccgaggcc cgcgcggttg tcgacctgca cgcgatgcac ggccagttcg
    12241 ataccccagg cctcgcattg ctgctggcag tgcagcaccc agtcatccgc atcgggctgc
    12301 aggccgtggt gcacgtgcac cgcgcgcagc gccgtgccgg aggcctgggc gcagcgccac
    12361 agccagtgca gcagcacggt ggaatcgaca ccgccgctgt agcccaccag caggggcgca
    12421 tccagcggaa caagggcagg gaaggcggtc acggcggcaa gtatagggtt ggtcggcagg
    12481 gctgcgccct gcacccgcag acgcgcaagc aacggcaacg gccgaagcaa cagcagcagc
    12541 tggtttcctg agggttggcg gggtggggcc ggttgcggga gacgccgtta acccgtccat
    12601 gggggcttgg ccgcggcatc catgccgcgg acactcccgc aaccggaccc atcccgcctt
    12661 cgacagtttc ctgcgagctg tcgggcatgt tgatggggtc agatccgttt tccgtggaaa
    12721 acggatctga ccccggattc aattcgatat ctgacagatt tcatccacgc atggcgtgga
    12781 tctactggcc gccggagaac tgtcgaaggc ggggcattgt gggtttgcgg ggtgtgagcc
    12841 gcatggatgc ggcgatcaag gctacacgga cgtacttgcg ccgtccccgc aaacccacag
    12901 tgccctgcca tgccacggaa cgcacgctgt tgcttcggcc gttgccgttg cgtcggcagg
    12961 tgcagggcgc agccctgccg aaaaacctac ttcacccgac ggcccgaacg gtcgatgcgg
    13021 aaccgctctc cgccttccat cggcgtgtgg ccatcggcat ccggcgtacc acgacggcaa
    13081 ccgttgcaga cctcggccac gccatcctgg aacggccacc cgaaatcgaa ggtgccaggc
    13141 accacctggc ggaacttcag gtcgaagtag ccgacgcggt tgccgacacg ggcgcgcagc
    13201 aggccttcct gcggtgtttc cggaccgttg tcccaggtca gtaccggcag gctgcggccc
    13261 gtgccgtcga catagtggaa gccctggtcg gcgtacacca cggccaggcc gtggtcgtcg
    13321 tagttcaggt ccttcagcgt atcggcgccg atcttcggcc ggtgatcgac gacctcgcag
    13381 ttgggcagcg gccacaaccc gtgttcgtcg gtcagcagct tgcacgccgg tgcctgtgcc
    13441 gctgcattgg cactgaccag cacgccaagc aggaccagcg accgcgcgaa gcggccgctg
    13501 gcgggggcag ggcgggcctg ccgtgcgatc acttggcttc ggccttgcgt tcgaaggccg
    13561 tcggtgccgg cagctgcacc ggcacgccct tgtcatcgca ggtgccggcc tggcacaggc
    13621 gctcgcgcag ggccggggtg gcctgcacga tcatgtggta gatcgcgttc tgttccagcg
    13681 tgccgcggat cgccttgctg cccgggccgc gtgcccagat accgacgtct tcgccgccat
    13741 gcgactcgga cttcattggc accagtgctt cctgcatgta gtccggatgc tcggtgtcga
    13801 cctcgcgcag gttcgggcga ccgttggccg gttcgaagct gctcgggttg tgtgggtagc
    13861 gcttggtgcc ggccggctgc tggttgctgg cgccggtgtg tcccgggcca ttggcgtagg
    13921 tcagggtggt gtacggctgg ccgctgccgt ccagcgcgta gtccagcttg ccggcgccgt
    13981 cttcgccgcc cttgtccttc accttgccca ggatcgggtt gccgcgtgcc gggtagccga
    14041 cgaagttcag cgtgtgcgag tggtcggcgg tgacaatgat cagggtgtca tcggccgagg
    14101 tcagttcgtt ggccacgcgc accgcgtcgg acagggccac ggtttcggtc agtgcacggt
    14161 aggcgttgcc gctgtggttg gcgtggtcga tgcgcgcgcc ttcgatcatc agcacgtagc
    14221 cttcctggtg cttggccaga ttcttgatgg ctgcagccgt cagttcggcc aggctcggct
    14281 caccacccgg atcctgcggg cgctcgtact cgtagcgcat gtggtccggc tcgaacaggc
    14341 cgaggatggc cggcgcattc gcggccgccg ccagctgctt gctgttccag acgtaggcac
    14401 cctgcggatg cgcctgctgc cattcctgca ccaggctgcg gccgtccagg cgctggccga
    14461 ccttgtcgtc gtactccgga tcacgctctt ccacggtggt gaattcaccg cggccgccac
    14521 cgagggcgac cagcgggcca cggccatagc gcgaggtcga cagcagctgc tgggcgatgt
    14581 ccttgcagcc ggccgccttg gccgcttcag tcaggtcggt gtcgttttcc cagttgcgct
    14641 cgggcgaatg cgcataggtg gcggccggag tggcatgggt caggcgtgcg gtggacacca
    14701 cgcccgtggc caggccggcg ctgtcggcca gctgcagcca ggtcagcagg cccttggaca
    14761 gactgtcggc gcagtcggtg cggctgccgg cgctgacgcc gatcgcgccc atgtgggtct
    14821 tcacgccggt ggtgatggcg gtcatggtgc cggccgaatc cggggtctgc gaatcggtgt
    14881 tgtaggtctt gctgaacgcc gtggccggga agcgctccca ggacagcagg ttctcttcac
    14941 ccgaaccacc cttctgctgg ccttcgtaga tgcgcgaggc cgccacggtg gtcaggctca
    15001 tgccgtcacc gaggaacagg atgacgttct tggccttgcc ggacatcgcg ccgttggcgg
    15061 cggcctgggc ggcgccactg cggtaccacc actgcggggt ctcgccggcc ggatgggcga
    15121 cgggatcgac ggcaaccttc aggccggccg gggcggatgc gggggcggtg ctggcgcagg
    15181 cgcccagcag cagggtggtg gcgcaggcgg ccaacaggga gacggaacgg cgcatggacg
    15241 ctgggatctc acaaactgta acgggacgtt cattatgccc ggccccgcaa ggcacgccga
    15301 tgacacactg atttgccggc cgggcggtcg ttctgcgggc cgccttgggc tatcgtgcca
    15361 gcatcccttc cttcccctct ggattgccta tgaagctggt ctctgcctgg ctgcggattc
    15421 cattctggca gcgcgtggtc ggtggcttcg tgctcggcgc gctggccggc tgggcgctcg
    15481 gcccggccgc ggaaacgtgg ttcggcccgc tcggcgagct gtacgtcacc ctgatcaaga
    15541 tgatcgccgt gccgctggtg ttcttcgcgg tcatcaacgc gatctcgtcg ctgcacggcc
    15601 agaagtcggt cgccgcgctc agtggccgca ccttcctgtg gttcgtgatc accgccgcgc
    15661 tggcggtgtg cgtcggcttg ggcgtgggca ccgtgctgca gcccggcgcc ggtggcctgc
    15721 aactgaccat ggccagcaac tacgtgccgc gcgaagtgcc cagcgtggtg caggtgctgc
    15781 tggacgtggt accggccaat gtcttctatg cgctgtccgg catcggcacc aaggtcaacg
    15841 cagcgggtga aaccgtgctg gccgccggac gtggctcgat cctgccggtg atcttcttcg
    15901 ccggcctggt gggctttgcc atcgtcaagc tgggcgagaa ggtgaccgag gctcgcaagc
    15961 tggtcggcca gatgagcgac atcatgatcc aggtgacccg cttcgtgctg gaagtcaccc
    16021 cgatcggcac cttcggcctg atcgccggcc tggtcggcag ctatgggttc gagaagctgt
    16081 tgccgctggg ccatttcgtg cttgccctgt acgtggcctg cgccctgcac atcgtggtgg
    16141 tctacagcgc gctgctgctg gcgcacggcc tgaacccgct gaagttcttc cgtggcgcgg
    16201 cgccgggcat gcaggtcgcc ttcgtcagct cgtccagctt cgcagcgatg ccagtggcgc
    16261 tgcgttcgat cacccacaac ctgggcgtga acaaggacta cggttcgttc gcggtgccgc
    16321 tgggcgccag catcaagatg gatggctgcg gtgcgatcta cccggcgctg tgcgcggtgt
    16381 tcatcgcgca gtacagcgga gtgccgctga ccccggaaca gtatgtggtg gtgttgatcg
    16441 cctcggtgct gggcagcttc ggtacggccg gcgtgccggg tacggcggtg atcatggcca
    16501 cggtggtgct gagcgcggcc aacctgccgc tggagaccat cggctacctg tatgccatcg
    16561 accgcatcct ggacatgatg cgcacgatga cgaacgtgac cggccagatg ctggtgccgg
    16621 tgatcgtggc gaaggaaacc gggctgctcg accaggcggt gtatgacaac ccgtccagca
    16681 atgtgggtgt ggacgatcct gacccgacgc cgccacgcgg ctgaggttgc gtggagatga
    16741 aaggcccgcc ctgaccggcg ggctttttgt tttggagttg actggcgcgg tgccgatcag
    16801 agtaggttcc tggtagatcc acgccatgcg tggatggcgg cagtgccgac caaggtcggc
    16861 agctacccac cattgggacc caacaaaaaa gccgctgcag ggcagcggct ttctcgtatc
    16921 aggcggcgcc gtggcgccag cgcggggcag atcagagatc gacccggcgg gcctgcatga
    16981 acttgttgcc ccagtagcca ctgagcaggg tgtccacgcg gacgtctttg cccgagctcg
    17041 gcgcatgcag gaagcggccg tcgccaacat agatgccgac gtggtcaaca cggcccttgc
    17101 ggccgaagaa caccaggtca cccgcggcca gcgcggtgcg gtcgttgatc agttcggcgt
    17161 tgtcgtcatg cgccatctcg cgcgagacgc gcggcagctc gatgcccagg gccgagcgga
    17221 acacgtagcc gaccaggccg ctgcagtcga aaccgctgtc cgggttgctg ccaccccaac
    17281 ggtacggggt acccagcagg gtcatcgcac ggcgcagcag cgactgcacc ttgccgttgt
    17341 cggcggcggt gccgacaacg ctgccattgg cggcgctgct ggtgtcgtag ttggcgagca
    17401 ggcggctgag atcaccggcc accactgccg agcggtccat cagcggaatg gtgtcgttgg
    17461 cggccaggtg cggcagcagg gcggccagcg tggcgctggc ggcggcatcg acgcggctgc
    17521 gctgcggagc ggcagcctcg gccttggcgg ccggtcgggc ggtgctctcg gccacctggg
    17581 ccggggtcac atcggaacgg ttcggagcgg tctgcgacca ggccggaagg ctggtcagac
    17641 acagtgccag gccaagcaac agcgggcggg cactacgtga agatacggaa gtctggcctt
    17701 cgcttttcag gtcgtcagtc gtcacgcgtc ggtcacagga aaaaaacgat ggggcatcat
    17761 gccctgtaaa agcggcaata agttaaaaat tccgttagta aatcgttatt ttcagggtga
    17821 tggccgtcac agttttgaac atatcgcctg ttcattttag cgaagaacgc gtttcgcccc
    17881 tgtgtaatgg tctttccagt agggaccgct gagcgagtcg aggcgtaccg ttccgccggt
    17941 gctcggcgca tgcacgaagc gcccttcacc tacataaata ccgacatggg tgacgctgcc
    18001 gcggctgccg aagaacacca ggtcgccggt ggccaggcgc tgcggatcga tcttcgggcc
    18061 ctgtaccgcc gcgaggtcgc gcgaggtgcg cggcagtttc aggtccagca tctcgcgata
    18121 gacataggcg accaggccgc tgcagtcgaa gccagagtcc ggcgtgttgc cgccgtagcg
    18181 gtagggcgtg ccaaccaggc tgatggcacg catcagcacc gagttggccg cctcggggtt
    18241 gtccggcacg gtcttcggcc agttcgccgt cggcgggggc ggcgcgggtc gggtggcctt
    18301 gccgccgccg caggcggtca tcagcacggg cagggccagc agcagggccg gggcgaggag
    18361 ccggcgcagg ccggacgaaa ctggcgtgat gtgcatgatc tccggataat gcgccacctt
    18421 gggattggcc gtcatgatgg cggcgtcccc gccgggcgac aacccgcccc aacccgcctg
    18481 ccttcggcag atccagacag agttgcgcat gaagatcgaa aaagaccgcg ttgtccgctt
    18541 ccactacacc gtttccgaag tcggccagga gccgatcgaa tcgtccaagg accgcggcga
    18601 gccgctggcg atcctgatcg gccacggcaa catcatcccg ggcctggaaa acgccatgat
    18661 ggacaaggaa gccggcgcga ccttcaacgt cgacgtcaag gcggccgatg cctacggcga
    18721 gcgccgcgag ggcctgtccc agcgcgtgcc gaagaagcac ttcggcaaca ccaagctggc
    18781 cccgggccag caggtggtgc tgcagaccaa cttcggcccg cgtgcggtga ccgtgcagaa
    18841 ggtcggcatg agcgtcgtcg acgtcgacct gaaccatccg atggctggca aggacctgca
    18901 tttcgatgtg gaaatcgtcg atgtgcgcga agccggcaag gaagagatcg accacggcca
    18961 cgtccacggc gacggcggtc accagcactg atcgcagcgc gatcgtgatg gcagcaacgg
    19021 cccgcttcgg cgggccgttg cgtttctgga acacgacgcg gccatccatg gcgtgtgggc
    19081 cggcggcata atggcggacc tgcctgacgg acgccccgtg aacgccgctt ctccttccct
    19141 gcagccggtg gcttccggcg aacgcatcgc cgtgttggac gtgctgcgcg gtgctgcgct
    19201 gctgggcatc ctgctgatga acatcgaggc cttcagcgga ccgctggatc tggctttcac
    19261 cggcatcgac gtgcactggc ggggcatcga ctactgggca gatgcctttg tgtacgtgtt
    19321 cgtgcagggc aagttcttca ccctgttctc gctgctgttc ggcgccggct ttgcggtaat
    19381 ggcgcagcgc gccgaagtgg ccgggcgcga cttcaccccg ttctacctgc gtcgcagcgc
    19441 tgccctgctg ctgatcggcc tgtgccacgc gctgctggtc tggtccggtg acatcctggt
    19501 gatgtatgcg ctgatctcgc ttccgttgct ggcctgccgc gaggcgccac gcagctgggt
    19561 gccgtggatg gggctgatgg tctacctcgg cggtgtggcg atgatgctgc tggtcggcgc
    19621 gatggtgtcg atggcttcgg ccgaagatgt gcagggcatg cttgctgagg cgcagcggag
    19681 catcgagctg cagcggcagg tgtacgggca gggcagctgg gcgcaggtca atgtgcagcg
    19741 gctgagcgag ttcggtacgt cgatgggcgc tctgctgatc accggcccgg aagtgctggg
    19801 catgttcctg atcggcagct ggttcgccgg cagtggtgcg ttggcggcac cggagcgctt
    19861 cccgcggctg tacgcgtcgc tgcgctggat cgcgttgccg ctgggcctgc tggtcacgct
    19921 gatcggcgtt gcctggaaac cctacctggc accgggcgcc tacaaccttc cggtgacggc
    19981 ggcgatgggc ctggtgacca taggcggcct gccgatgtgc ctgggctatc tcgcgtggat
    20041 cgtgcactgg cgcacgcggc tggcctggct ggcgccggtg gggcgcatgg cgctgaccca
    20101 ttatcttggc cagtcgctgc tgtgcacgtg gttgttctat cactatggcc tgggcggctt
    20161 cgagctgatg ccgcgcagcg tgcagctgct gttcgcactg ttgttgtttg ccgtgcaggt
    20221 ggccctttcg catgtctggt tgcgccgctt ccgctttggc ccgatggaat ggctgtggcg
    20281 tgcgatgacc taccggcagt ggccgccgat gcggcgcgag gccgggcagg gctgatcgat
    20341 gcagggcgcg cgcgaggatg tgatcgtggt cggcgccggt gccattggac tggccgccgc
    20401 gctggcgctg cgcgcacagg gccggcaggt gcgggtgatc gaccgtgggc gtgtcggcgg
    20461 cgcgacctcg catggcaact gcggcaccat cacccccagt cacgcgccac cgctggcagc
    20521 gcctggtgtg ccgttgcggg cgctgcgctg gatgctcgat ccgcgtgcgc cgctgtacgt
    20581 gcgtacgcgc ctggaccctg cattgtggcg ctggctgctg cagttcgggg cgcgctgcaa
    20641 cgcgcgtgac tggctgcact ccacgcgggc acgcggcgca ctgttgaatg attcacggct
    20701 gcgcctggcg cagtgggtgc agacgcatgc gctggactgc gaattcgagg cgcgcggtct
    20761 ggactatgtg ttcggtgaca cccgcaattt cgatcaccac gctgccgagt gtgaggcgct
    20821 gaatgcgcag ggtattgcca cggcgcgcat cgatggcggc gactacgcgc gcgacaatc
//
