LOCUS       NZ_CP104900            12187 bp    DNA     circular CON 13-OCT-2024
DEFINITION  Shewanella seohaensis strain KCTC 23556 chromosome, complete genome.
ACCESSION   NZ_CP104900
VERSION     NZ_CP104900.1
KEYWORDS    RefSeq.
SOURCE      Shewanella seohaensis
  ORGANISM  Shewanella seohaensis
            Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
            Shewanellaceae; Shewanella.
REFERENCE   1  (bases 1 to 4751888)
  AUTHORS   Liu,G.-H.
  TITLE     Taxonomy and metabolic features of ten novel Shewanella species
            tbased on genome analysis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4751888)
  AUTHORS   Liu,G.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-SEP-2022) Center for Microbial Electrochemistry,
            Fujian Agriculture and Forestry University, shangxiadian road,
            fuzhou 350002, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025449215.1-RS_2024_10_11
            Annotation Date                   :: 10/11/2024 19:44:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,230
            CDSs (total)                      :: 4,090
            Genes (coding)                    :: 3,472
            CDSs (with protein)               :: 3,472
            Genes (RNA)                       :: 140
            rRNAs                             :: 10, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 618
            CDSs (without protein)            :: 618
            Pseudo Genes (ambiguous residues) :: 0 of 618
            Pseudo Genes (frameshifted)       :: 605 of 618
            Pseudo Genes (incomplete)         :: 21 of 618
            Pseudo Genes (internal stop)      :: 5 of 618
            Pseudo Genes (multiple problems)  :: 12 of 618
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:10:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1255862
            Orig. end                         :: 1268049
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP104900.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Fujian Academy of
            Agricultural Sciences.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..12187
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..12187
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12187
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7187](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7187
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(163..1089)
                     /locus_tag="N7V09_RS05720"
                     /old_locus_tag="N7V09_05720"
     CDS             complement(163..1089)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011624060.1"
                     /locus_tag="N7V09_RS05720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N7V09_05720"
                     /product="nuclease-related domain-containing protein"
                     /protein_id="WP_248967037.1"
                     /transl_table=11
                     /translation="MVDFTNNLLSIVIILSSMFVTIGVMYALLKYRDATVTLPVDREQL
                     SRIPAYGLQKQIQDLQLDLIGSMMMGLMIVCFPFAISSIQAHIAVGKFPWVYALTGLMG
                     LTYCGIKTWKNFSKLTKLRLGHTAEIATANELIGLQALGYQVFHDVQADGFNIDHLVIG
                     KNGVFAIETKGRHKRNKDLRQTNGNGGGSSSSSGKKGYEVFYKDGRLNFPSWTETKPIE
                     QAERQSKWVSQWLTKATGSPVAATPALVFPGWYVTSQSKPPFPILNHKQLVGTIPKLKT
                     QDLSQQQVDTIIYQVAQRCLSKSEVGK"
     gene            complement(1453..1698)
                     /locus_tag="N7V09_RS05725"
                     /old_locus_tag="N7V09_05725"
     CDS             complement(1453..1698)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006080205.1"
                     /locus_tag="N7V09_RS05725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N7V09_05725"
                     /product="DUF3297 family protein"
                     /protein_id="WP_011624059.1"
                     /transl_table=11
                     /translation="MTDTTSQPALPDRLSVNPRSRHHVAEVFQYDVGIRVNGKERFDVE
                     EYCISEGWVKVPSKSLDRRGQPLLLTIKGTVEAFYR"
     gene            1989..2378
                     /locus_tag="N7V09_RS05730"
                     /old_locus_tag="N7V09_05730"
     CDS             1989..2378
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011071091.1"
                     /locus_tag="N7V09_RS05730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N7V09_05730"
                     /product="ribosome recycling factor family protein"
                     /protein_id="WP_248967036.1"
                     /transl_table=11
                     /translation="MHDDISIPLPSLIHRIGREAVKRAQAIAVQKGCELKRVRRSRNWS
                     ITGQAIAIQSCCVELKGQSDTAEFAFMIKKIDSGLLQHADKLEPLGAKLVRLINQNPAI
                     TLGELMQQTQCTMSEARLARFEAEL"
     gene            complement(2561..4225)
                     /locus_tag="N7V09_RS05735"
                     /old_locus_tag="N7V09_05735"
     CDS             complement(2561..4225)
                     /GO_component="GO:0098561 - methyl accepting chemotaxis
                     protein complex [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197653.1"
                     /locus_tag="N7V09_RS05735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N7V09_05735"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_248967035.1"
                     /transl_table=11
                     /translation="MSNFSLRNKLLLLALFPLILTLIVLMTVSYHVEQSALADEVTTFR
                     EKLIGERKTQIKEATQIAAGIVQYQLSLKEQGNVNQALRDIRFGSSGYFFIYDSQGKNL
                     FHAVMPNLEGQNKIDMTDPRGTKIIVGLLNAAKNGDGNFSFYFQKPNTNEQIEKIGYSM
                     MIPGTDWMLGTGAYIDDIDAVVEDYRTTVTEQMIDKSYAILLIALLLAAITAAVILVTA
                     QRMVTPIKNMADNLNDIAKGEGDLTKRLAVKGDDEIAQLGRSFNLFVDKLQTIIGDVAD
                     ATAKVKTAANAIHDQTKVMSRQLISHNNETDQVVTAITEMSATASEVAQNTTQVAEATH
                     AATGDVANAQRCVDASLEEISALMAQINNAASNIQSLSEQSKKINSVLSVIGGIAEQTN
                     LLALNAAIEAARAGEQGRGFAVVADEVRNLASRTQSSTLEINEMLSELHKLVSLAVKTM
                     EESQQSCIRSVDSSRAISESLGSVTSAVTAINDMSTQIATAATEQSSVTEEINRNVFAI
                     QEIVNELLHSSEEAASVSQTVSQEGLNLGKLVGQFKI"
     misc_feature    complement(4384..4397)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.35"
                     /tool="antismash"
     gene            4542..4784
                     /locus_tag="N7V09_RS05740"
                     /old_locus_tag="N7V09_05740"
     CDS             4542..4784
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011718279.1"
                     /locus_tag="N7V09_RS05740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N7V09_05740"
                     /product="hypothetical protein"
                     /protein_id="WP_041408884.1"
                     /transl_table=11
                     /translation="MTNQRLITLLKICIGLGLCLIMLGIYLHNFNETVEAMGVKGIIIS
                     AVCVAVGMALSLPTKMYLTFLLVKREADKQGSAEH"
     gene            5001..7187
                     /locus_tag="N7V09_RS05745"
                     /old_locus_tag="N7V09_05745"
     CDS             5001..7187
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012156470.1"
                     /locus_tag="N7V09_RS05745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N7V09_05745"
                     /product="OsmC domain/YcaO domain-containing protein"
                     /protein_id="WP_248967034.1"
                     /sec_met_domain="YcaO (E-value: 5.1e-73, bitscore: 244.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKVNFLDNLRLEAKFDDFTVTADQPIRYKGDGSAPSPFDYFLA
                     SSALCAAYFVKVYCKSRDIPTDNIRLSQNNIVDPEDRYNQIFQINVELPDDISDKDREG
                     ILRSIDRCTVKKVVQTGPEFRIETVENLDADANAMLMGHPGDDSSTYILGKDLPLEQTI
                     ANMTGILAELGMKIEISSWRNIVPNVWSLHIRDAASPMCFTNGKGATKESALCSALGEF
                     IERLNNNFFYNDQFFGVEIANSEFVHYPNEKWFALEEDDALPAGLLDDYCLEIYNPDEE
                     LCGSHLIDTNSGNRDRGICAIPYKRKSDGETVYFPSNLIENLFLSNGMSAGNNIKEAEV
                     QCLSEIFERAVKRQIIEQEIVLPDVPMSVLEKYPSILAGIKGLEEQGFPVVVKDASLGG
                     QFPVMCVTLMNPKTGGVFASFGAHPSFEVALERSLTELLQGRSFEGLNDVPKPTFNSMA
                     VSEPENFVEHFIDSTGVISWRFFSSKHDYEFCEWDFSGTNQEEADRLFGILEDLGKEVY
                     VAEFTALGASACRILVPDYSEVYPVEDLIWDNTNKALDYREDILNLHSLSTKQLVNLVN
                     RLEESQLDNYTDIRTLIGIVFDENTVWGKLTIIELKILIYLALGAHEEALELVGEFLQF
                     NDNTVKRNLFFQAMSAVLEVTLDEDLELEDFSHNFTRMFGAEVMEQVVGSVTGKVRFSG
                     LTKTSMQLEGIEPHLRLIESYKKLHAARKANAVK"
     gene            complement(7310..8548)
                     /locus_tag="N7V09_RS05750"
                     /old_locus_tag="N7V09_05750"
     CDS             complement(7310..8548)
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024758.5"
                     /locus_tag="N7V09_RS05750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N7V09_05750"
                     /product="serine protease"
                     /protein_id="WP_248967033.1"
                     /transl_table=11
                     /translation="MENYPKNIINKNKKMRLLNIALFILLLCSFHADSTEHSVKSSTIS
                     SRIQIKDINQVLSAQSVGTLVITRNRFSKDTQSLCTGILIADDYLMTAAHCIIDHMTGE
                     GVLNAEFIPQYLGDGKQIRSRVFIEKGWVHKKYLTTDYKDILQFKNGLVSLNRKPNTSD
                     LAILKVTNSQTGYGLGKQYGYVSPIAAEDVLTTKKPNVSLLSYPADKSGNTLWYQQCHL
                     TEHKSLIGKFDCQIYSGSSGAGLLIKAPNSDKDRVLGIVSSSSDNGLSGAAVLFSTEMI
                     QDIENIIKNRTESIKHFSAVKFKTTPRTYVHIENLCKKEIIAMVYSEENNQGMVSESKI
                     PVNTSVIFNSIQSRIWYSHIRDLEGKPYNFGNDILLDVNNKSYYFKKNIIPYKNIGNGS
                     VFYGDYFLKVYCI"
     gene            complement(8551..8949)
                     /locus_tag="N7V09_RS05755"
                     /old_locus_tag="N7V09_05755"
     CDS             complement(8551..8949)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N7V09_RS05755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="N7V09_05755"
                     /product="hypothetical protein"
                     /protein_id="WP_262251773.1"
                     /transl_table=11
                     /translation="MRYSQEEMKTAYNNVMKKCKPMGAIFGALVGTIPALAIYISFVFM
                     NVNGPIWILCILPPAVIGMFSRFVGRTFRPEHRIPTGLIGAITHILGCYILGSGIIFYL
                     LAPINFAIAMIASKNKAKRSRRMGNLSS"
     misc_feature    complement(9039..9054)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.25"
                     /tool="antismash"
     gene            complement(9251..10159)
                     /locus_tag="N7V09_RS05760"
                     /old_locus_tag="N7V09_05760"
     CDS             complement(9251..10159)
                     /EC_number="2.7.7.65"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011845791.1"
                     /locus_tag="N7V09_RS05760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N7V09_05760"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_248967216.1"
                     /transl_table=11
                     /translation="MVSVEQMALVLDALPDPAFILSQSGRYVAVFGGKDARYYHDGSGL
                     VGLYLSDVLNDEKTTYYLKIIQQALDSRKLLIEEYELSNKDVKGLSDQGPSEPIWFEGR
                     IQALDFLVDNEPVVLWVASNISKRHKLEIQLRQLSDTDQLTGLYNRRRLDRDLHFLFDT
                     FSRHRIPASILVLDLDHLKLINDQLGHQAGDRVIMAVAEACQQQFRKTDSAYRFGGDEF
                     VIALPGVDHDQAIVFAEYLCDCCFKALQQLSVKGLFATVSIGVASIEAGDKSYEDTLKR
                     ADAALYQAKRNGKNRVIANTA"
     gene            complement(10450..10911)
                     /locus_tag="N7V09_RS05765"
                     /old_locus_tag="N7V09_05765"
     CDS             complement(10450..10911)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011625134.1"
                     /locus_tag="N7V09_RS05765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N7V09_05765"
                     /product="redoxin family protein"
                     /protein_id="WP_248967032.1"
                     /transl_table=11
                     /translation="MLRILLLMLLCCALPLSAAQLTRDYQFQALRGQQVTDLSHLEGQA
                     MALMFFEPECPWCIKQASVLKQLHQSCHQGVQPVALGVNGDNLALKRALFRLNFPFEAY
                     RAPPALLKDMGGIPATPILLLLNTKGELIKGYRGFTDEAELKAQLCRSS"
     misc_feature    11019..11035
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 24.96"
                     /tool="antismash"
     misc_feature    11365..11385
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.74"
                     /tool="antismash"
ORIGIN
        1 aagatagaga tgagtgatgg aagctttaaa ttaattaaag tctaactatt ttattagatg
       61 ttgattttta attcatgaaa ggtttcactt ttgtgttctc aggatttatg tgattcagca
      121 aatctaagtc agagttaagt tattaactac tgttaattct cgttatttcc ccacctcgct
      181 tttacttagg catctttggg cgacttggta gatgatggtg tctacttgtt gctggctaag
      241 atcttgggtt ttcagtttcg ggatggttcc gactaattgt ttgtggttaa ggatcgggaa
      301 cggtggtttc gattggcttg tgacatacca gccggggaat acgagggctg gggtggcggc
      361 gacgggggag cctgtggctt tggttaacca ttggctgacc catttgcttt gccgttcggc
      421 ctgttcgatg ggtttggttt ctgtccacga ggggaagttt aagcgcccgt ctttgtaaaa
      481 tacttcatag cctttcttac cagaactaga actagagcct ccgccattgc cattggtttg
      541 gcgtaggtct ttattgcgct tatggcggcc tttggtttca atcgcgaata cgccattttt
      601 accgattacg aggtggtcga tattaaagcc gtcggcttgc acatcgtgaa acacttgata
      661 acccaaggct tgtaggccga taagttcatt ggcggtagcg atttcagccg tatgccctag
      721 acgtaatttg gtgagtttgg aaaagttttt ccaagtttta ataccgcaat aagttaatcc
      781 cattaaacct gttagggcgt aaacccaagg gaatttcccg acggcaatat gtgcttgaat
      841 actgcttatt gcaaagggga aacacactat catcagcccc atcatcatgc tgccgattaa
      901 atctaattgc agatcttgga tttgcttttg taagccatag gcgggaatac ggctgagttg
      961 ctcgcgatca acgggcaggg tgacagtagc atcacggtac ttgagcagcg cgtacatcac
     1021 tccaattgtg acgaacatgc tggagaggat gatcactatc gataaaagat tgtttgtaaa
     1081 atctaccatt tacatccttg aaatagaaag gtttatcgtt aattccataa cgcacacatg
     1141 atgaatgtgc ttgatacctt ggtggcagag gaggctgtta agagtggggc ggcatggtac
     1201 agattggctg ctttgtcctt aaatagcgtg ctcgatagtg gcgttcgagt gtggctctgc
     1261 atttccctta gtggtcacac tttaacccgc gttatgcggt gtaatcaatg cgttttatca
     1321 caaaagctta ttttaaataa caacttgtga atacttgggg agatgaatta ctgagggttt
     1381 tggggttata cagggcaaat aaaaacggcc aatcgaattg gccgttttta ttatccatta
     1441 agcagtgggt gcttaacggt aaaatgcttc tactgtgcct ttgatggtta acagcagagg
     1501 ttgaccgcga cggtctaaag atttgcttgg tactttaacc cagccttcgc tgatgcagta
     1561 ttcttcaaca tcgaaacgtt ctttaccgtt cacgcggata cccacatcgt attgaaagac
     1621 ttcagctaca tggtggcggc tgcgtgggtt aaccgaaaga cgatccggta atgcgggttg
     1681 tgaagttgtg tcagtcatgg tcgttatctg tagtgaacaa aaagtgcgtt attgtaggca
     1741 atcccgccgc cttgctcaag gactgttgtt gtcagtctgt gacgcctgag ccgctatctt
     1801 gggcgagggg cgcttagcgt gagttgatgc gtgagttgtt gcatgagttt gtatcgtctt
     1861 ttgttcgcac ccgccgcagg gtaaactctg gcggcgttgg ctataggttt cgcgcttaag
     1921 gcttaagact tagcgccgcg ctccgttatt cacccatatt cgacccaagg cccgatagtt
     1981 aacttgccat gcatgatgat attagtattc ccttgccatc ccttatccat cgcatcggcc
     2041 gcgaggcggt caagcgggcg caggcgattg ctgtgcaaaa gggctgcgag cttaagcggg
     2101 tgcgccgctc ccgtaattgg agcatcactg ggcaggctat cgcgattcaa agctgttgcg
     2161 tcgagttaaa agggcagagt gatactgccg aatttgcctt tatgatcaaa aagatcgaca
     2221 gcggcttatt acaacatgcc gataagcttg aaccactcgg cgcaaaattg gttcgcctga
     2281 tcaaccaaaa ccccgccatt accttgggcg aactgatgca acaaacccaa tgcacgatga
     2341 gcgaggcgcg ccttgctcgc ttcgaggccg agctttgata ccgaactcta ttatgttggg
     2401 ttattagcaa gcagccacca agaaaaaggc ctcaattgct tgaggcctta ggcggttaaa
     2461 gatagcgatt tataccgaat cgactaacac tgaatcgact tacgccgagg tgatgaacac
     2521 ctaatcgact aacagcgagc gccgatatca cgccttagcg ttaaatctta aattggccga
     2581 cgagtttgcc gaggttaagt ccttcctgcg acacggtttg gctcacgctc gccgcctctt
     2641 cgctggagtg cagtagctca ttcacaattt cttgaatagc aaacacattg cgattgatct
     2701 cttcggtcac tgagctttgc tcggttgcag cggtggcgat ttgggtactc atatcgttaa
     2761 tggcggtcac cgccgaggtc actgagccta agctttcgga gatggcgcgg gacgaatcca
     2821 ccgagcgtat acaactctgc tgactctctt ccatggtttt aaccgctaag ctcaccagct
     2881 tgtgcagttc agatagcatc tcgttgattt ctaatgtgct tgattgagta cggctggcta
     2941 agttgcgtac ctcatcggcc accacggcaa agccgcgacc ctgttcaccc gcgcgggcgg
     3001 cttcaatcgc ggcgtttaat gccaacaggt tagtttgctc ggcaataccg ccgatcaccg
     3061 agagcacgct gttgattttt ttggattgtt cactcaagga ttgaatgttg ctggcggcat
     3121 tgttgatttg cgccatcagc gccgaaatct cctctaacga ggcatcgaca caacgctggg
     3181 cattggccac atcgcccgtg gcggcgtggg tcgcttcggc cacttgggtg gtgttttgcg
     3241 ctacttcact cgcggtggca gacatctcag taatggcggt aaccacttga tccgtttcat
     3301 tgttatggct gataagctgg cgcgacatca ccttggtttg gtcatgaatc gcattggctg
     3361 cggttttgac cttagcggtg gcatcggcca catcaccgat aatggtttgc agtttatcga
     3421 caaacaggtt gaaggagcgg ccgagttggg cgatttcatc gtcgcccttc accgcaaggc
     3481 gcttggttaa atcgccttcg cctttggcga tatcgtttaa gttatctgcc atgtttttaa
     3541 tcggtgtgac catgcgctgg gcggtcacta agatcacggc ggcggtaatg gccgctaata
     3601 acagtgcgat caataaaatc gcgtaggact tatcgatcat ctgctcggtc actgtggtgc
     3661 ggtaatcctc aaccacggca tcgatatcgt cgatataggc gccggtgccg agcatccaat
     3721 ctgtgcctgg gatcatcatg gagtagccga ttttttcgat ttgctcgttg gtattgggtt
     3781 tttggaaata gaacgagaaa ttaccgtcac cgtttttggc ggcattgagt aggccgacaa
     3841 tgatcttggt gccacgggga tcggtcatat cgattttatt ctgcccctcg aggttgggca
     3901 tgaccgcatg gaataggttt ttaccttggg aatcgtaaat aaagaagtag cccgaactgc
     3961 caaagcgaat atcacgtagg gcttggttaa cattgccctg ttcttttaac gatagctggt
     4021 attgcactat gcctgcggcg atttgggtgg cttctttgat ttgggtttta cgctcaccga
     4081 ttaacttttc tctaaatgtg gtgacttcat cggcaagcgc cgattgctcg acatggtagg
     4141 aaactgtcat cagcactatg agggtcagaa tcaacgggaa cagtgcgagt aggagcaatt
     4201 tgttacgtaa actgaaatta gacatgttca acaactccgg aataagccgc tttattattg
     4261 cagggcagta taacgaatcc ccaatattct taagtgctta agttaacaaa aatctaatgt
     4321 aaccgacaaa agtgcaaagt ggtatttgac ttaaggatga gggcgaaagg ctgagtcact
     4381 tcgttgatct taatcaaagc ctaaataagc caatgcgctc attatattag ttaatcttta
     4441 tgcataggcg gcgcttgttt gtttgagtgg ctaaacggtg cgacgcaagc ttaaacaaga
     4501 cgactctagc tcaatcaagg cgtgcaacta aaggcaggac tgtgactaat caaaggctga
     4561 taacgctgtt aaaaatctgc attggccttg ggctgtgcct gattatgctt gggatttatc
     4621 tgcataactt taatgaaacc gtcgaagcca tgggcgtaaa aggcataatt atcagcgccg
     4681 tttgcgttgc cgttggcatg gcgttatccc tgccgacaaa gatgtatctc acctttttac
     4741 tggttaagcg cgaggcggat aagcaaggca gtgctgagca ttaacccttg gctaacccac
     4801 agtgaatgcc gcaattaatc ctaccgttct gcttgcggcc caaggcataa aaatcccgct
     4861 ggtgtttttt aacataatta acccaagact aatgggcgaa aaacaccgat aattccccca
     4921 agacgatagc gcccaagggc aatgctgtgc ggtaacgaat gcgattatcg cgtttgagca
     4981 tattgagtgg aaaaattcta atggaaatca aagttaattt tctcgacaac ctgagactcg
     5041 aagccaagtt cgacgatttt acggtaacgg ccgatcagcc catccgttat aagggcgacg
     5101 gctcggcgcc gagtcccttc gactacttct tagcttcttc ggcattgtgc gccgcctact
     5161 ttgtgaaggt atattgtaaa tctcgcgata ttccgacgga caatatccgc ctgtcgcaaa
     5221 acaatattgt cgacccagaa gatcgctaca accagatttt ccagatcaat gtcgaattgc
     5281 ccgatgatat ttcggataaa gatcgcgaag gtattttgcg ctccatcgac cgctgcaccg
     5341 tgaaaaaagt cgtgcagact ggcccagaat ttagaatcga aaccgttgaa aacctcgatg
     5401 ccgacgccaa tgccatgttg atgggtcacc caggcgacga cagcagcacc tatattttgg
     5461 gtaaagactt accgctagag cagaccattg ccaatatgac tggcattttg gctgagctgg
     5521 ggatgaagat tgagatctcc tcatggcgta acattgtgcc caatgtgtgg tcactgcata
     5581 tccgtgatgc cgcatcgccc atgtgtttta ccaatggtaa aggcgcaacc aaagagagcg
     5641 cgctgtgctc ggccctcggt gagtttatcg agcgtttaaa caataacttc ttctataacg
     5701 accaattctt tggggttgag attgctaaca gcgagtttgt gcattatccc aacgaaaaat
     5761 ggtttgctct cgaggaagac gacgctctgc cagcggggtt gttagacgac tactgcctag
     5821 agatttataa ccccgatgag gagctgtgtg gctcgcatct tattgacact aactcgggca
     5881 atcgtgaccg tggcatttgt gcgattccgt acaagcgtaa atccgatggc gagactgtgt
     5941 acttcccatc aaacctgatt gaaaacctgt tcttaagcaa tggcatgagc gcgggtaaca
     6001 acatcaaaga agccgaagta cagtgtctgt ctgaaatctt cgagcgcgcg gtgaaacgcc
     6061 aaattatcga gcaggaaatc gttctgccag acgtgcctat gtcggtatta gaaaaatacc
     6121 caagcattct tgcgggcatt aagggcttag aagaacaagg cttcccagtg gtggtgaaag
     6181 acgcctcctt aggcggccag ttccctgtga tgtgcgtgac gctgatgaac ccgaaaaccg
     6241 gcggggtatt cgcctccttc ggtgcccacc caagctttga agtggcattg gagcgcagtc
     6301 tgaccgaatt gctccaaggt cgcagcttcg aaggcttaaa cgatgtgcca aaaccgacct
     6361 ttaacagcat ggcggtgagc gagcctgaaa actttgttga gcactttatc gactcaacgg
     6421 gggtgatctc atggcgcttc tttagcagca agcatgacta tgagttctgc gaatgggatt
     6481 tctctggcac taaccaagag gaagcggacc gcttattcgg cattttagaa gatctaggta
     6541 aagaggtgta tgtcgccgaa tttaccgcat taggcgcatc ggcttgccgt attttagtgc
     6601 ctgattactc tgaagtttat ccagttgaag acctgatttg ggacaacacc aacaaggcgc
     6661 tggattaccg tgaagatatc ctaaatctgc attctttaag cactaagcaa ttggttaacc
     6721 tagtcaatcg tttagaagaa agtcagctcg ataactacac cgatattcgt accctgattg
     6781 gtatcgtctt cgatgaaaat accgtctggg gcaagttgac gattatcgaa cttaagatcc
     6841 tgatttatct ggcactcggc gcgcatgaag aggcgctgga attagtcggt gagttcctgc
     6901 aatttaacga caataccgtg aagcgtaatc tgttcttcca agcaatgagc gcggtactgg
     6961 aagtgacgct ggatgaagac cttgaactcg aagactttag ccataacttt acccgcatgt
     7021 ttggcgcaga agtgatggaa caagtggtcg gcagcgttac gggtaaagtc cgtttcagcg
     7081 gtttaactaa gaccagtatg cagctcgaag ggattgaacc gcacctaaga cttatcgaaa
     7141 gctataaaaa actgcacgcc gcccgcaagg ctaacgcggt taagtaagac tcaacagagg
     7201 cttgcatcaa actaacctaa acagtgttga tgcaagcctc taaatcgtag ttcctagttt
     7261 gatgttatag gccatcgtac agtactgtgt ttaataaacg cagcttgtat taaatacagt
     7321 atacttttag aaaataatca ccataaaaaa cacttccatt gccaatattt ttatatggaa
     7381 taatattttt tttaaagtaa tatgatttgt tattaacatc tagcaatata tcattgccaa
     7441 aattgtaagg ttttccttct agatctctaa tatgactgta ccatattcta gattgtatgc
     7501 tattaaaaat tacggatgta ttaactggta ttttactctc agaaaccatt ccctgattat
     7561 tttcttctga atataccatg gcaataattt cttttttgca aagattttca atatgcacat
     7621 aagttcgagg tgttgtttta aattttacgg cgctaaaatg tttaatcgat tcagtgcgat
     7681 ttttaataat attctcaata tcctgtatca tttcagtaga aaaaagaacc gctgcacctg
     7741 atagtccatt atccgatgaa gatgaaacta tccctaacac tctatcttta tcagaattag
     7801 gtgcctttat tagcaatcct gcaccactag aacccgagta gatttggcag tcaaacttcc
     7861 ctattaatga cttgtgttct gttaagtgac attgttgata ccataatgta ttaccacttt
     7921 tatctgctgg ataacttagt aaactaacat taggtttttt agtggttaac acatcttctg
     7981 ctgcaatagg ggaaacatat ccgtactgct tccctaagcc atatcctgtt tggctgtttg
     8041 tgacttttag tatagctaaa tcactcgtat ttggtttgcg attgagtgag actaaaccat
     8101 ttttgaactg taaaatatct ttataatcag tggttaaata ttttttgtga acccatcctt
     8161 tttcaatgaa cactcttgaa cgaatttgct taccatcgcc aaggtattgt ggaataaatt
     8221 ctgcattgag cacaccctca ccagtcatat ggtcgataat gcagtgcgcc gctgtcataa
     8281 gatagtcatc agcaattaga atacccgtac atagtgattg agtatctttg ctaaatcgat
     8341 ttcttgtaat gaccagagta cctacgcttt gagctgacaa cacttgattg atatctttaa
     8401 tctgtattct ggagcttatc gttgagcttt taacagaatg ttccgtagag tcggcatgga
     8461 aactacaaag gagtagaatg aataatgcta tatttagtaa tctcattttc ttatttttat
     8521 ttattatgtt tttaggatag ttttccaata tcagcttgat aaattgccca ttcttctact
     8581 tcgcttagct ttgtttttgc ttgctatcat tgctatcgca aaattaatcg gtgctaatag
     8641 ataaaaaatt attccacttc ctaatatgta acatcctaaa atatgagtta ttgctccgat
     8701 tagccctgtg gggatacgat gctctggtct aaaggttctt ccaacaaagc gtgaaaacat
     8761 gccaattaca gctggaggca aaatgcataa aatccaaata ggtccattaa cattcataaa
     8821 aacaaatgat atataaattg ctagcgccgg aatggtaccg accaatgcgc caaaaatagc
     8881 acccataggt ttgcattttt tcataacatt attatatgct gttttcatct cttcctgaga
     8941 atatctcatt atattagcct tgtttaaatt ttgagtgtaa atatttttct gttgacttga
     9001 ttatgtataa gcaatcatgt cgtctaaggt aaaatagggt taataattgt aaatgagttt
     9061 attcactcta tcaatttatt aatcttacaa taactggttt ttttgatatt tatcttaaat
     9121 gtttttgtat attaggcttg tgtgaatttg ttttattaca atgtgttatg attataaggt
     9181 cataaattct gtgggtgata tgttgcaagg tgaactcata tcaagctcta tactatccta
     9241 ttgtcggaaa ttaagccgta ttggctatta cgcgattctt accattccgc ttggcttgat
     9301 agagcgcggc atcggcgcgc tttagggtgt cttcatagga tttatcgccc gcttctatgc
     9361 tggcgacacc tatgctgacg gtggcaaata atccttttac cgagagttgc tgcaatgcct
     9421 tgaagcaaca gtcacagaga tattcggcaa acactatggc ttggtcatgg tcaaccccgg
     9481 gcagggcaat cacaaattca tcgccaccaa aacggtaggc gctgtcggtt ttgcgaaatt
     9541 gctgttggca ggcttcggcg accgccatga tgacgcgatc acccgcttgg tgccccagtt
     9601 gatcgttaat aagcttcagg tgatccagat cgagcactaa gatcgaggcc ggaatacggt
     9661 ggcggctaaa ggtgtcgaag agaaagtgta agtcacggtc taagcggcgg cggttataga
     9721 gtccagtcag ttggtcagta tcacttaatt gccgcagttg tatttctagc ttatggcgtt
     9781 tggaaatatt actggcgacc cagaggacga cgggttcgtt atccactaga aaatctaacg
     9841 cctgaatgcg cccttcaaac cagatgggtt ctgaaggacc ttgatcggat aagcctttga
     9901 catccttatt actgagttca tattcctcaa tcagtaattt acggctatct aaggcttgct
     9961 gaataatctt gaggtagtaa gtggtctttt cgtcgttgag tacatcgctc aggtaaaggc
    10021 caactaatcc actgccgtcg tggtaataac gcgcatcttt accaccaaac acagcaacat
    10081 agcggccgct ttgtgacagg ataaacgccg gatcgggtag cgcgtccagc actaaagcca
    10141 tttgctcaac actgaccatc aaacaagctc cctatacgtt aaagggtcta atagattgaa
    10201 gcactcttag ttggctcctt gtctgctatt gcacccatta ctcactatcg ctggcccatg
    10261 tggctttttc aaacctaggc aagggcatgt cggagtaaca ctctaagtgt atctgatgtt
    10321 ggcgttgaac agtgtagatt aatgtaggtt ttattggcaa aaacctattg ttctcaatcg
    10381 gaatggtgtg ccatttaatg gcatcaaaca acactctgat tgaaaacaat agattaaatt
    10441 atgctgatat taactcgagc ggcagagttg agccttcagc tctgcttcat cggtaaaacc
    10501 gcgatagcct ttgattaact ctcccttggt attgagcagc agcaggattg gcgtggcagg
    10561 aataccgccc atatccttta gcaaagcggg cggcgcgcgg taggcttcaa aggggaaatt
    10621 cagcctaaac agggcacgtt ttaaggctaa gttatctcca ttgaccccaa gcgccacggg
    10681 ttgcacgcct tgatgacagc tttgatgcag ctgcttcagt acactggcct gcttgatgca
    10741 ccaagggcac tcaggctcga aaaacatcaa tgccatcgct tgcccctcga gatgtgacaa
    10801 gtcagtcact tgctgacccc gcaaagcttg aaactgatag tcgcgggtga gctgcgccgc
    10861 cgataacggc agggcgcagc acagcaacat aaggagaaga atgcgcagca ttagaagcta
    10921 aacttcatgc cagcgtagat ttctctgcca cgcagtgggc catagatata gcccacgtcg
    10981 aaggcgccct cggcatcgta aaacagtggc gtgtcttcat cccccgcttg ggtatagtca
    11041 aacagattgc tgaccccagt gtagagtgac agggtatcgt tgagctgata actgaccttt
    11101 aaatctaaag tcacgtaagc gggcgcatcc gtggtctttt tcgagctagg gtcgacttgg
    11161 ccattggcat cgaggcggtt atagccttcg tagccaaagt cggcgagatc gcgactaccg
    11221 atccacacta ggttggcaaa aatttcccag tcattcacgt cccaatccat gctgaggctg
    11281 acccttttct ccactggcgc aatggcatag gaggatttga atactgaatc ataatcaaaa
    11341 tgctcggcgg taaggcttaa actcatatcg tcggtcaagc gataacctaa ggcaatatcg
    11401 ctggtgataa cccgcgcttt ttcatcgagc tgggtcagta atggaatgcc atggtcgtta
    11461 gtggttaatg ccgctaaatg ctcgacttcg gtccaagcaa tcgaggcggt agaggtgagg
    11521 cgttcacctt cgtaactcag ggcatagttg actgagttgg agcgctctag ctcgtcgata
    11581 tcgatgtcaa agcccagaga gccgtctaaa atgccgtggt cggtttcaaa gaaggataat
    11641 ggcgcgcgat agccgcgacc tgcggatagg cgcgaggtcc attcatcatt gtggcgcaga
    11701 cgaatgtcga ccctaggcga cagaatcgac tcatcgagtt cggtgccggg tttgttgggg
    11761 tcggtaaaat cggcgctgat agtatcgtaa cgcagcgcca tcgcgacttc taacgactca
    11821 gtggcttgcc aagtgtcctg tagataaacg cctttgacat catagtcaaa ggagtcggaa
    11881 acatagtcag ggttggcact gcccgagcgg gaatgggagc gcatttcctc tgtgcgtaag
    11941 tcggcgccga aggtgagtag ttggctctcg ctcaacagat aattaaaacg tgcatcgaag
    12001 aaccacatct tgtcatcggc gctgtaatcg aagccttcgt agaaggagtc ctgtttatga
    12061 tcggcgtagc tggcggcaag gtgcatgttc cagtcgtcgt taaattccct cagccaagcg
    12121 agtgaggctt cgttacgttc ggtcttaatc cattcggtgg tttcccaggc ttttcctgtg
    12181 tagcgct
//
