LOCUS       NZ_CP104864            21086 bp    DNA     linear   CON 13-OCT-2024
DEFINITION  Streptomyces lusitanus strain FZ202 chromosome.
ACCESSION   NZ_CP104864
VERSION     NZ_CP104864.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces lusitanus
  ORGANISM  Streptomyces lusitanus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7417890)
  AUTHORS   Zhang,F.
  TITLE     Streptomyces lusitanus FZ202
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7417890)
  AUTHORS   Zhang,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-SEP-2022) College of Life Science and Technology,
            Jinan University, Guangzhou, Guangzhou, Guangdong 510632, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2021
            Assembly Method                   :: unicycler v. 3.14.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 213.8x
            Sequencing Technology             :: Illumina NovaSeq6000; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025427835.1-RS_2024_10_11
            Annotation Date                   :: 10/11/2024 19:56:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,707
            CDSs (total)                      :: 6,615
            Genes (coding)                    :: 6,460
            CDSs (with protein)               :: 6,460
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 155
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 83 of 155
            Pseudo Genes (incomplete)         :: 88 of 155
            Pseudo Genes (internal stop)      :: 3 of 155
            Pseudo Genes (multiple problems)  :: 19 of 155
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:00:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4940405
            Orig. end                         :: 4961491
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP104864.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zhang Fei,  College of Life
            Science and Technology.
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="11"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11086
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(149..1465)
                     /gene="aroA"
                     /locus_tag="N7E53_RS22755"
     CDS             complement(149..1465)
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522882.1"
                     /locus_tag="N7E53_RS22755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_033272064.1"
                     /transl_table=11
                     /translation="MAPNPTHTALWPAPHASGAVDATVHVPGSKSVTNRALVLAALASE
                     PGWLRRPLRSRDTLLMAGGLRAMGVEIEEGVGPDGTGEAWRVVPAGLRGPATVDVGNAG
                     TVMRFLPPVATLADGPVRFDGDPRSYERPLNGVIDALRGLGARIDDDERGALPMTVHGG
                     GALDGGTVEVDASSSSQFVSALLLSAPRFNQGVEVRHTGSTLPSMPHIRMTVDMLRAVG
                     AQVDTPEAGGEPNVWRVTPGALLGRDLTVEPDLSNAQPFLAAALITGGKVVIPDWPART
                     TQPGDRLREIFTEMGGSCELTEYGLVFTGSGAVHGIDVDLGEVGELTPGIAAVAALADS
                     PSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHIRPRRLHGGVFHTYEDHRM
                     ATAGAVIGLAVDGVQIENVATTAKTLPDFPELWTGMLGA"
     gene            complement(1552..2274)
                     /locus_tag="N7E53_RS22760"
     CDS             complement(1552..2274)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992842.1"
                     /locus_tag="N7E53_RS22760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_033272656.1"
                     /transl_table=11
                     /translation="MVSTASASLASLWDEVAGTQPDPDLWVVVATLVAALAVVVPQAPW
                     RIARNAITIAHEGGHGLVALLTGRTLTGIRLHSDTSGLTVSRGRPTGIGMILTAAAGYT
                     APPLLGLGGAALLGAGRITLLLWLATALLLAVLVMIRNAYGAVSVLVTGGTFVLVSWLA
                     GPQVQAAFAYAVVWFLLLGGVRPAFELQAKRRHGGAGDSDADQLSRLTHVPAGLWLFLF
                     HAVSVCSLLGGGRWLLGL"
     gene            2335..3150
                     /locus_tag="N7E53_RS22765"
     CDS             2335..3150
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="N7E53_RS22765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_033272063.1"
                     /transl_table=11
                     /translation="MCGRYAASRRPEDLAGIFEIEKWEPEETLEADYNVAPTKEVYAVL
                     DRPLKDADDPRPVRQLRTLKWGLVPSWSKTPEGGARMINARAETVHEKPSYRRAFTSRR
                     CILPADGYYEWVTGKQERDLEVEGKKKRPRKQPYFVTPADGSVFAMAGLYEFWRDRTLP
                     DDHPRAWWVTCSVITTEAERSPLAVAPAEGPHTLAEIHPRMPLMLTQDRWDAWLDPSRT
                     DPEDLRGLLAPPEPGLMRAYPVTTAVSNVRNNGPELLKELAAPEEGTLF"
     gene            3152..3826
                     /locus_tag="N7E53_RS22770"
     CDS             3152..3826
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674889.1"
                     /locus_tag="N7E53_RS22770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_033272062.1"
                     /transl_table=11
                     /translation="MTTEPAATPESDVTDVTTETIPTDAGDARITWHHAGRPRLVLAAS
                     HGAGGGIEARDLVALAAVLPAHGVTVALVEQPWRVAGKKVAPAPKTLDTGWRGVWPALT
                     QPGLPVISGGRSAGARVACRTAVELDAHAVLALSFPLHPPGRPEKSRADELLGAGVPTL
                     VVQGGNDPFGKPAEFPAGDHELVEVPRADHGFAVPKRADLTQEEALRVVTDAVVRWTAG
                     LA"
     misc_feature    complement(4016..4030)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.77"
                     /tool="antismash"
     gene            4086..4772
                     /gene="sigR"
                     /locus_tag="N7E53_RS22775"
     CDS             4086..4772
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="N7E53_RS22775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_033272060.1"
                     /transl_table=11
                     /translation="MGPVPGTDAGTEHGQAEQPEGQGDTRAESTAERSARFERDALEFL
                     DQMYSAALRMTRNPADAEDLVQETYAKAYGSFHQFREGTNLKAWLYRILTNTFINSYRK
                     KQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKEALQAIPEEFRIA
                     VYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGAGESNE
                     AKGSGS"
     misc_feature    4108..4123
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.19"
                     /tool="antismash"
     gene            4769..5071
                     /gene="rsrA"
                     /locus_tag="N7E53_RS22780"
     CDS             4769..5071
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326971.1"
                     /locus_tag="N7E53_RS22780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_033272059.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEILDHLYEFLDREMPDADCQKFEHHFEECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPGDLRSKVMGRIELIRSGHNVPEKDVTAAPQES"
     gene            5211..6590
                     /locus_tag="N7E53_RS22785"
     CDS             5211..6590
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134738.1"
                     /locus_tag="N7E53_RS22785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_261675599.1"
                     /transl_table=11
                     /translation="MEALPARARVYLVGVTLLGLCCLLPLPGVPRPGVLSSLPDPRVPW
                     WPVVLLAALYAGCERLARSRLVAGPHPGGAFHPVLLAGAFLLPPTAAALVALPGALLLP
                     VEHGPHLARRLWRTGRLVVAVWAASLVHLKTGGRDAVAHCDMPGALATAGVAVLAFCLV
                     LTLLDGGVLVPAPGGLPRSRPVAAWWRLFLGSLAPLTVHGLAGLMMALLWRSPYGPVAA
                     LLVLLPMGVSWWAFAQYHRERAAHQATIRALVQAVDIKDGYTRGHSERVGRASMLIARE
                     LGMDDERVETLRFAGILHDVGKLGVPTRLLTKNGPLTPEERRVIELHPEYGHEMVRGIS
                     FLGEARAAVLHHHERLDGTGYPYGLAGGQIPESARVVAVADAFDAMTSTRSYSRARPVP
                     VALEELERCAGTHFDPRMVKALVTAIGRTGWHPAVTADEPRRTAVPGPAGHVTGRPGAR
                     R"
     misc_feature    5220..5222
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6587..7849
                     /locus_tag="N7E53_RS22790"
     CDS             6587..7849
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522889.1"
                     /locus_tag="N7E53_RS22790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_193466594.1"
                     /transl_table=11
                     /translation="MRPRAHTVPLHTVVHLCAAVLAAGSLGTTLYHGVDDRSTALAFGT
                     LVAVGELTRRGGRGIREPAPVAAAGSLAYALLGEVAGRPAGHGAAQVVTVVLAASLLGS
                     VPHVGRGDGPALDPVTRRVLTVGFVAVCFHPLHARGAFEDFSGPGHALLLLVLLTLTAL
                     CDAVLAAALAHSRTGWPFPPLLRDELRAVPGIGAAVVATGAVMALGAAVVGLWALPVFS
                     VPLLLAQLSHRRYTAVRATYRQTIASLARATEIAGYTPHGHSRRVAALSQAVGRDLGLT
                     EPELTVLEYAALMHDIGQLSLVDPVPEGATAGLPPAEQRRIALLGGAVVRQTGVDPRVA
                     GIVERQADPHAEQPLAARIVRVVNAYDEKCREGGPGGPLTALEELRLGAAGEYAPEVVE
                     ALARVLSRDTEGTREQVDRSW"
     gene            8006..8986
                     /locus_tag="N7E53_RS22795"
     CDS             8006..8986
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="N7E53_RS22795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_019522890.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRDTGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLKVPGPATDSGEPLGMDLGSAAVRLSPEGEAEVVWGRRLDPARIEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERSTAAGHTYPVFDEIELWAPSPVPTWVVLLEAASEADRD
                     ALEQLASDAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGIAAPASLVRGLLDGWVADSPDSRDWRDLEEVC"
     gene            9134..9784
                     /gene="def"
                     /locus_tag="N7E53_RS22800"
     CDS             9134..9784
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="N7E53_RS22800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptide deformylase"
                     /protein_id="WP_033272057.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHAGVLPVDDEGYVIDTEDCEKREAEWRERGTSRPIT
                     VVGNPVLHKECKDVTDFGEEFQQLVADMFASQRTAEGVGLAANQIGVDLKVFVYDCPDD
                     EGVRHVGVVCNPKLVELPAERRRLDDSSEGCLSVPTAYAPLARPDYAEVTGQDEKGNPI
                     RVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKAALKQMAENEPRYPVVAND"
     gene            10001..11086
                     /gene="cyc1"
                     /locus_tag="N7E53_RS22805"
     CDS             10001..11086
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992851.1"
                     /locus_tag="N7E53_RS22805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_033272654.1"
                     /sec_met_domain="T1TS (E-value: 9.5e-66, bitscore: 221.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHALSHGSTSTPTTIAVPPALSLPVIEAAFPRRLHPYWPKLQRET
                     RAWLLEKRLMTPEKVEEYADGLCYTDLMAGYYLGAPDEVLQAIADYSAWFFVWDDRHDR
                     DIVHGRPDAWRRLKDLLHSALDRPGDHLGHQDPVVAGLADSVRRLHAFLPDTWNARFAR
                     HFHAVIEAYDREFHNRTEGVVPTVEEYLELRRLTFAHWIWTDLLEPSAGYELPDAVRKN
                     PAYRKPALLSQEFAAWYNDLCSLPKEIAGNEVHNLGISLVTHEGMTLEEAIADIRRRVE
                     ECISEFLDAEQEALRFADRLDDGTVGGKETSAAVRACVGNMRNWFSSVYWFHHESGRYR
                     VDSWDDRSTPPYVDNATEGEK"
     misc_feature    10883..10885
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11083..12450
                     /locus_tag="N7E53_RS22810"
     CDS             11083..12450
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190553.1"
                     /locus_tag="N7E53_RS22810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_033272056.1"
                     /sec_met_domain="p450 (E-value: 2.7e-69, bitscore: 232.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVRPEDTAATAEPPVAGGAVPLLGHGWRLVRDPLAFLSQLR
                     DHGDVVRLKLGPKTVYAVTTPALTGAVALSPDYIIAGPLWESLESLLGKEGVATANGPL
                     HRRQRRTIQPAFRLDAIPAYGPIMAEEAYALVERWRDADGVLDITYESFRVAVRVAARC
                     LMRGGYMDAHADRICADLTTLFAGMYQRMVVPLGPLYKIPLPANREFNRALADLHVLVD
                     EIVADRRASGQKPDDLLTALLEAKDDNGDPIGEQEIHDQVIAILTPGAETVGSTIMSLL
                     LVLTEHPELGDKIRDEVKSVVGDRPVAFEDVRKLTYTANVVTETLRLYPAVWILTRRAV
                     ADTELGGYRIPKGADLIYSPFAVQRDRRSYERNEDFDPDRWLPERSKDVPKYAMSPFSV
                     GNRKCPSDHFSMAELTLVTAVVAHAYGFEHASDSDPRPRIGITLRPRRLMLRALPR"
     gene            complement(12473..13435)
                     /locus_tag="N7E53_RS22815"
     CDS             complement(12473..13435)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020700022.1"
                     /locus_tag="N7E53_RS22815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_193456174.1"
                     /transl_table=11
                     /translation="MLRNVAAVLLDGVNPFELGVVCEVFGIDRSDDGLPVYDFAVVSAE
                     GASVRASAGFTLQTEHGLDRLDAADLITVPAGVSYTSREFPPEMLDALRRAVDRGARVL
                     SVCSGAFVLAAAGLLEGRRAAVHWKHAEELSRRYPHLTVEPDVLYVDEDPVITSAGTAA
                     GIDACLHLVRKEQGPEVANRIARRMVVPPHRDGGQAQYIERPLPEPGGDSVAGVLVWME
                     QHLDEEVTVEQLAARALMSPRTFARRFQQETGTTPYRWILRQRVLLAQHLLERTDETVD
                     AIAGRAGFGNAAALRHHFVRAVGTTPQSYRRAFRGPEAA"
     gene            13529..13750
                     /locus_tag="N7E53_RS22820"
     CDS             13529..13750
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925877.1"
                     /locus_tag="N7E53_RS22820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_203550129.1"
                     /transl_table=11
                     /translation="MNTTQTEALIAMVAVLGLFVLMVAPAVIGILRDRRIDRQIRRARA
                     TLVTEPPGMPAASRPEHRAASRRHARAA"
     gene            complement(13772..14728)
                     /locus_tag="N7E53_RS22825"
     CDS             complement(13772..14728)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142309.1"
                     /locus_tag="N7E53_RS22825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_230229915.1"
                     /transl_table=11
                     /translation="MRYPDFYERYRDAIKNTWHVEEVDLHSDVADLAKLTPEEQHLIGR
                     LVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEEAVHVQFYLTLLDTYLPDPD
                     DRAAAFAAVENIPSIREKAEFCFRWMDSVEKIDRLESRADRRRFLLNLICFAACIEGLF
                     FYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFDVVDTVRKEEPELFDEELGR
                     QVTDMLREAVAAELQFARDLCGDGLPGMNTASMRQYLECVADQRLVRLGFAPVYGSENP
                     FSFMELQGVQELTNFFERRPSAYQVAVEGTVDLDEDF"
     gene            complement(14785..17148)
                     /locus_tag="N7E53_RS22830"
     CDS             complement(14785..17148)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444560.1"
                     /locus_tag="N7E53_RS22830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_261675600.1"
                     /transl_table=11
                     /translation="MTIAPADPASATRVTEDSDGPGAALLRTLTQLTADLPDADAGRVA
                     AAALRGRSASADEAELRDLATEAAAGLISEDPAYSRLAARLLTLGIRAEAASQGVTSFT
                     GSVAAGHREGLIGDRTAAFVRLHAARLDALVDTDADDRFGYFGLRTLHSRYLLRHPVTR
                     KVVETPQHFLLRVACGLAEDESERALEDVAALYGLMSRLDYLPSSPTLFNSGTRHPQMS
                     SCYLLDSPKDELDSLYERYHQVARLSKHAGGIGLSFSRVRARGSLIRGTNGHSNGIVPF
                     LKTLDASVAAVNQGGRRKGAAAVYLETWHADVEEFLELRDNTGEDARRTHNLNLAHWVP
                     DEFMRRVDADAPWSLFSPVDVPELVDLWGEEFDAAYRAAEAKGLARRTLPARELYGRMM
                     RTLAQTGNGWITFKDTANRTANQTAEPGHVVHSSNLCTEILEVTDDGETAVCNLGSVNL
                     AAFAGPDGMDWERLDAAVRTAVTFLDRVVDINFYPTGEASRSNSRWRPVGLGVMGLQDV
                     FFRLRVPFDSPEAKALSTRIAERIMLAAYETSAGLAERHGPLPAWEKTRTARGVLHPDH
                     YGVELAWPERWEALRSRIAATGLRNALLLAIAPTATIASIAGVYECIEPQVSNLFKRET
                     LSGEFLQVNSYLVEDLKRLGVWDARTREALREANGSVQDFAWIPEDVRRLYRTAWEIPQ
                     RGLIDMAAARTPFLDQAQSLNLFLETPTIGKLSSMYAYAWKQGLKTTYYLRSRPATRIA
                     RAARAAVPVPVQQPADPEAVACSLENPESCEACQ"
     misc_feature    17199..17210
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     regulatory      complement(17273..17442)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(17394..17407)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     misc_feature    complement(17401..17415)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(17432..17446)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.73"
                     /tool="antismash"
     gene            complement(17494..17997)
                     /locus_tag="N7E53_RS22835"
     CDS             complement(17494..17997)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326961.1"
                     /locus_tag="N7E53_RS22835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_033272051.1"
                     /transl_table=11
                     /translation="MDIVIRPATPGEHADLGEITAQAYLGDGLLDFGESDSYLDELRDV
                     GKRAAAAEVLVAVADGALLGGVTFVPGPGPMADIAEPGEAEIRMLAVSPAHRGRGAGEA
                     LVRACVDRARALGRTRMVLSTQRTMHSAHRVYERLGFTRAPGRDWNPLPELDDIMLLVY
                     ELTL"
     gene            complement(18078..19706)
                     /gene="mctP"
                     /locus_tag="N7E53_RS22840"
     CDS             complement(18078..19706)
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006848 - pyruvate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mctP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="N7E53_RS22840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="monocarboxylate uptake permease MctP"
                     /protein_id="WP_033272050.1"
                     /transl_table=11
                     /translation="MNDGVNGVALAVFIFFFVLVTVMGFLAARWRKAANEHTLDEWGLG
                     GRSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGAAGFFAVPYTILVYPLIFTFLPRLW
                     SVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     ENTNWFIKDLPLLLAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGG
                     FDEIFASAQEAYSETNPATGAPRGALVPGEAGQWTYATLALGSALALFMYPHSITATLS
                     SRSREVIRRNTTILPLYSLMLGLLALLGFMAIAAGVKVQNGQLAIPQLFENMFPDWFAG
                     VAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPKQETAVSKIVSLLVKVGAL
                     VFVLTMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALIGGWAVGMIYGTVAAY
                     GVASPTQKHFGGSAKEIPGIGEIGYIGLTAFVINVLVTVVLTFVMRAVKAPDGVDETEP
                     RDYTADAGDPGVQVELPPATADSKH"
     gene            complement(19703..19924)
                     /locus_tag="N7E53_RS22845"
     CDS             complement(19703..19924)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522900.1"
                     /locus_tag="N7E53_RS22845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_051724313.1"
                     /transl_table=11
                     /translation="MRVVIGLCLLAPFVAMLWVGSYAKTDPVFIGIPFFYWYQMLWVLI
                     STALTMIAYKLWQRDQRARSAAKGGAEQ"
     gene            complement(20159..20923)
                     /locus_tag="N7E53_RS22850"
     CDS             complement(20159..20923)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="N7E53_RS22850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_033272048.1"
                     /transl_table=11
                     /translation="MSTDVSSTENEGGTAVRTARVPKYYRLKKHLLDMTETAPPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDLGYITADDRLAGLLDITAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLTKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SLDRGGQPVEWVRSVYRGDRYKFVARLKRPQD"
     misc_feature    complement(21058..21073)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.17"
                     /tool="antismash"
ORIGIN
        1 ggccccggtc gaccgtgagc accatgccct cggcggcgtc ctcgtgcttg ggcctgatgt
       61 gggtgcgcgg ccggttgccc ttgcggttgg ggcgcgagcg gatgtcgtcc tcgtcggtgt
      121 gcttgccgta gcggcgcatc gtgaacccct acgccccgag catcccggtc cacagctcgg
      181 ggaagtccgg cagggtcttc gccgtggtcg ccacgttctc gatctgcacg ccgtcgaccg
      241 ccaggccgat gaccgcgccg gcggtggcca tgcggtggtc ctcgtaggtg tggaagacgc
      301 cgccgtgcag ccggcgcggg cggatgtgca ggccgtcggc cgtctcggtg acgtcgccgc
      361 ccagctcgtt gatctccttg gtgagggcgg ccagccggtc cgtctcgtgc agccgcagat
      421 gggccacgcc ccgcagggtc gacggggagt ccgcgagggc cgcgaccgcc gcgatgcccg
      481 gcgtcagctc gcccacctcg ccgaggtcca cgtcgatgcc gtgcaccgcg ccggagccgg
      541 tgaacaccag cccgtactcg gtcagctcgc aggaaccgcc catctcggtg aagatctccc
      601 gcagccggtc gccgggctgg gtggtgcgcg cgggccagtc ggggatcacc accttgccac
      661 cggtgatcag cgcggccgcg aggaacggct gggcgttgga caggtccggc tcgaccgtta
      721 ggtcccggcc gagcagggcg cccggcgtga cccgccagac gttcggctcg ccgcccgcct
      781 cgggggtgtc cacctgggcg ccgaccgcgc ggagcatgtc gaccgtcatc cggatgtgcg
      841 gcatcgacgg cagcgtcgac cccgtgtgcc gcacctcgac gccctggttg aagcgcggcg
      901 ccgacagcag cagggcgctg acgaactgcg acgacgagga cgcgtccacc tcgaccgtgc
      961 cgccgtccag cgcgcccccg ccgtgcaccg tcatcggcag ggcgccccgc tcgtcgtcgt
     1021 cgatccgggc gcccagcccg cgcagcgcgt cgatgacgcc gttcagggga cgctcgtagg
     1081 accgcgggtc gccgtcgaag cgcaccgggc cgtccgccag ggtggccacc gggggcagga
     1141 agcgcatcac cgtgcccgcg ttgcccacgt ccacggtggc cggaccgcgc agaccggccg
     1201 gcaccacacg ccaggcctcg cccgtcccgt cgggaccgac gccctcctcg atctccacgc
     1261 ccatcgcgcg cagcccgccc gccatcagca gcgtgtcgcg cgagcgcagg ggacggcgca
     1321 gccagcccgg ctcggaggcg agggcggcga ggacgagagc acggttggtg accgacttgg
     1381 acccgggcac gtggaccgtc gcgtcgacgg ctccgctcgc gtgcggggcg ggccagaggg
     1441 cggtgtgcgt ggggttcggg gccatggggc cactttataa gggagtgagg agcccggccg
     1501 ttccgtgccc gccaggcgga acgccgtccg gtcgaccgac cgcaggcccg gtcacagacc
     1561 cagcagccag cgccctccgc ccagcagcga gcacaccgac accgcgtgga agaggaacag
     1621 ccacagcccc gccggcacgt gcgtcagccg ggacagctgg tccgcgtccg agtccccggc
     1681 gcccccgtgc cgccgcttgg cctggagctc gaacgccgga cgcaccccgc ccagcagcag
     1741 gaaccacacc acggcgtacg cgaacgccgc ctgcacctgc gggccggcga gccacgacac
     1801 cagcacgaac gtgcccccgg tgaccagcac cgacaccgcg ccgtaggcgt tgcggatcat
     1861 caccagcacc gccagcagca gcgcggtggc cagccacagc agcagcgtga tgcgccccgc
     1921 gccgagcagc gccgccccgc cgaggcccag cagcggggga gcggtgtagc cggccgcggc
     1981 cgtgaggatc atgccgatgc cggtcggcct gccgcggctg acggtcaggc cgctggtgtc
     2041 ggagtgcagg cgtatgcccg tcagggtgcg gccggtgagc agggccacca ggccgtgccc
     2101 gccctcgtgc gcgatggtga tcgcgttccg cgcgatccgc cagggcgcct gcgggaccac
     2161 cacggcgagg gccgccacca gggtcgcgac gacaacccac aggtccgggt cgggctgggt
     2221 gcccgcgacc tcgtcccaga gggaggcgag ggacgcggac gcggtgctga ccatgctcgt
     2281 catgtgtgtt ggatcgctcc ctgtgcgcgt gcggagtctg gcagtgttgc acgtatgtgc
     2341 ggacggtatg cagcgagtcg gaggcccgag gatctcgccg ggatcttcga gatcgagaag
     2401 tgggagcccg aggagaccct ggaggccgac tacaacgtgg cgccgaccaa ggaggtctac
     2461 gccgtcctcg accgtcctct gaaggacgcg gacgaccccc gcccggttcg gcagctgcgc
     2521 acgctcaagt ggggactggt gccctcctgg tccaagaccc ccgagggcgg cgcccggatg
     2581 atcaacgcgc gcgcggagac cgtccacgag aagccgtcgt accgccgtgc cttcacctcc
     2641 cgccgctgca tcctccccgc cgacggctac tacgagtggg tcaccggcaa gcaggagcgc
     2701 gacctggagg tcgagggcaa gaagaagcgg ccccgcaagc agccctactt cgtcaccccg
     2761 gccgacggct cggtcttcgc gatggccggg ctgtacgagt tctggcgcga ccgcaccctg
     2821 cccgacgacc acccgcgggc ctggtgggtg acctgctcgg tgatcaccac cgaggcggag
     2881 aggagcccgc tggccgtggc cccggcggag ggcccgcaca ccctggccga gatccacccg
     2941 cggatgccgc tgatgctcac ccaggaccgc tgggacgcct ggctcgaccc ctcccgcacc
     3001 gaccccgagg acctgcgcgg cctgctcgcc ccgccggagc ccggcctgat gcgcgcctac
     3061 ccggtcacca ccgccgtcag caacgtccgc aacaacggtc cggagctgct gaaggagctg
     3121 gccgccccgg aagagggcac actcttctga cgtgaccacc gagcccgcag cgacccccga
     3181 gtccgacgtg accgacgtga ccaccgagac gatccccacg gacgccggcg acgcccgcat
     3241 cacctggcac cacgccgggc ggccgcgcct cgtcctcgcc gcgagccacg gcgcgggcgg
     3301 cggcatcgag gcccgtgacc tcgtcgcgct cgccgccgtc ctccccgcgc acggcgtgac
     3361 cgtcgccctc gtcgagcagc cctggcgcgt ggccggcaag aaggtcgccc cggcgccgaa
     3421 gaccctggac accgggtggc gcggcgtctg gcccgccctg acgcagccgg gcctgccggt
     3481 gatctccggc gggcgcagcg ccggcgcccg cgtcgcctgc cgcaccgccg tcgaactgga
     3541 cgcgcacgcc gtgctcgcgc tgagcttccc gctccacccg ccgggcaggc cggagaagtc
     3601 ccgcgccgac gaactgctgg gcgcgggcgt ccccacgctc gtcgtccagg gcggcaacga
     3661 ccccttcggg aaacccgccg agttccccgc gggcgaccac gaactggtgg aggtcccgcg
     3721 ggccgaccac ggcttcgccg tgcccaagcg ggcggacctc acacaggagg aggccctccg
     3781 ggtcgtcacg gacgcggtcg tgcggtggac ggcgggcctc gcctgaggag cgccgggaat
     3841 gcgtggaccg tccccgctgt tgtggggtgc gtacgtgccg gtcgaacggc accgccgccg
     3901 taggagagga agtccaccgc atgggttcca cgttctgccc gagccgcagt gcccgcgccg
     3961 acctcgactg gacggtgctg cacgcggcca agaccgcccc gattcgggcg gcgggcggac
     4021 cggatcgtcg tctatcctcc gattcgggtg aggccggtct cggtctcacg acgacacttg
     4081 aggaggtggg tccggttccc ggtaccgacg cagggaccga acacggccag gcggagcagc
     4141 ccgagggcca gggcgacacg cgcgcggagt cgaccgcgga gcgcagcgcg cgcttcgaac
     4201 gggacgcgct cgagttcctc gaccagatgt actcggcagc gctgcgcatg acgcgcaacc
     4261 cggccgacgc cgaggacctg gtgcaggaga cctacgccaa ggcgtacggg tccttccacc
     4321 agttccgtga gggcaccaac ctcaaggcgt ggctgtaccg gatcctgacc aacaccttca
     4381 tcaactcgta ccgcaagaag cagcgcgaac cccagcgctc cgcggccgag gagatcgagg
     4441 actggcagct cgcgcgcgcc gagtcgcaca tgtccacggg tctgcgctcc gccgagtcgc
     4501 aggcgctgga ccacctgccg gactcggacg tgaaggaagc cctgcaggcg atcccggagg
     4561 agttccgcat cgcggtctat ctcgccgatg tcgagggctt tgcctacaag gagatcgccg
     4621 acatcatggg gacacccatc ggaacggtga tgtcccgcct ccaccgggga cgtcgccagc
     4681 tgcgcggcat gctcgaggac tacgcccgcg agcgcggact ggtcccggcc ggtgccggag
     4741 agtcgaacga agcgaaaggc tcggggtcat gagctgcgga gagccgcacg agacggattg
     4801 cagcgaaatc ctcgatcatc tctacgagtt cctcgaccgt gagatgccgg atgccgactg
     4861 ccagaagttc gagcaccact tcgaggagtg ctcgccctgc ctggagaagt acgggctgga
     4921 gcaggcggtc aagaagctcg tgaagcggtg ctgcgggcag gacgacgtgc cgggcgacct
     4981 gcgctcgaag gtcatgggcc gcatcgagct gatccgctcc ggacacaacg tgcccgagaa
     5041 ggacgtcacg gccgctccgc aggagtcctg acacctcccc acccccgggg ccgcgtcacc
     5101 cgattgtgct aatccgcggg cggtacgccc gcgccggcgc cctcccccgc cctaggctcc
     5161 aggagccggc gggcgacgga aggcgcgcgg cacggtcggg ggaggggctc atggaggcgt
     5221 taccggcgcg ggcccgggtg tatctcgtcg gcgtcaccct gctgggactg tgctgtctgc
     5281 tcccgctgcc gggcgttccc cggccggggg tgctgtcgtc cctgcccgac ccgcgtgtcc
     5341 cctggtggcc ggtcgtcctg ctcgccgccc tgtacgcggg ctgcgagcgc ctcgcccggt
     5401 cccgtctcgt cgccggaccg caccccgggg gcgccttcca ccccgtgctg ctcgccgggg
     5461 ccttcctgct gccgcccacc gccgccgccc tcgtggcgct gcccggggcg ctgctgctgc
     5521 ccgtcgagca cggtccgcat ctcgcgcgcc ggctgtggcg cacgggccgg ctcgtcgtcg
     5581 ccgtgtgggc cgccagcctg gtgcatctga agaccggcgg cagggacgcg gtggcgcact
     5641 gcgacatgcc gggcgccctc gccacggcgg gcgtcgccgt gctggcgttc tgcctcgtcc
     5701 tcaccctgct cgacggcggt gtcctggtgc ccgcccccgg cgggctgccg cgcagccgtc
     5761 ccgtggccgc ctggtggcgg ctgttcctcg gctccctggc accgctcacc gtgcacggcc
     5821 tggccgggct gatgatggcc ctgctgtggc gcagccccta cgggccggtc gcggcgctgc
     5881 tggtgctgct gccgatgggc gtctcgtggt gggcgttcgc ccagtaccac cgggagcgcg
     5941 ccgcccacca ggccacgatc cgcgcgctgg tgcaggccgt cgacatcaag gacggctaca
     6001 cgcgcggtca cagcgagcgc gtcggccgcg cctccatgct gatcgcgcgc gaactcggca
     6061 tggacgacga gcgggtcgag acgctgcgct tcgccggcat cctgcacgac gtcggcaagc
     6121 tcggcgtgcc cacccggctg ctcaccaaga acggcccgct cacccccgag gagcggcggg
     6181 tcatcgaact gcaccccgag tacgggcacg agatggtgcg cggcatctcc ttcctcggcg
     6241 aggcccgcgc cgccgtgctg caccaccacg agcgcctcga cggcaccggc tacccctacg
     6301 ggctggcggg cggtcagatc ccggagtccg cgcgggtggt cgcggtcgcc gacgccttcg
     6361 acgcgatgac ctccacccgc agctacagca gggcgcgccc ggtgcccgtg gcgctggagg
     6421 agctcgagcg gtgcgcgggc acgcacttcg acccgcggat ggtcaaggcg ctcgtcaccg
     6481 cgatcggccg caccggctgg caccccgcgg tgaccgccga cgagccccgg cggacggccg
     6541 tgcccggtcc cgccggacac gtcaccggcc gtcccggggc gcgccggtga ggccccgcgc
     6601 gcacaccgtc ccgctgcaca ccgtcgtgca tctgtgcgcc gccgtcctcg cggccggctc
     6661 gctgggcacg acgctgtacc acggcgtgga cgaccgctcc accgccctgg ccttcggcac
     6721 gctcgtcgcg gtcggcgaac tcacccggcg gggcggccgg gggatccggg agcccgcgcc
     6781 ggtggccgcg gccggctcgc tggcgtacgc actgctcggc gaggtcgcgg ggcggcccgc
     6841 cgggcacggc gccgcccagg tcgtcaccgt ggtgctcgcc gcgtcgctgc tgggcagcgt
     6901 cccgcacgtc gggcgcggcg acgggcccgc cctggacccg gtgacccgca gggtgctgac
     6961 cgtgggcttc gtcgccgtgt gcttccaccc gttgcacgcc cggggcgcgt tcgaggactt
     7021 cagcgggccg ggacacgcgc tgctgctgct cgtcctgctg accctgaccg cgctgtgcga
     7081 cgcggtgctc gccgccgcgc tggcccactc ccgcaccggc tggcccttcc cgccgctgct
     7141 gcgcgacgag ctgcgggccg tgcccggcat cggcgccgcc gtcgtcgcca ccggcgcggt
     7201 gatggcgctg ggcgcggcgg tcgtggggct gtgggcgctg cccgtgttct ccgtgccgct
     7261 gctgctcgcg cagctgtccc accggaggta cacggcggtg cgcgccacct accggcagac
     7321 catcgcgtcc ctcgcgcggg ccaccgagat cgccgggtac accccgcacg ggcactcgcg
     7381 ccgggtcgcg gcgctcagcc aggcggtggg gcgggacctc gggctgaccg agccggagct
     7441 gaccgtgctg gagtacgcgg cgctgatgca cgacatcggg cagctcagcc tcgtcgaccc
     7501 ggtgcccgag ggcgccaccg ccggactgcc gcccgccgag cagcggcgga tcgcgctcct
     7561 gggcggcgcg gtggtccggc agaccggggt ggacccccgg gtcgccggga tcgtcgagcg
     7621 tcaggccgac ccgcacgccg agcagccgct cgccgcccgt atcgtccggg tggtgaacgc
     7681 gtacgacgag aagtgcaggg aaggagggcc cggggggccg ctgaccgcgc tggaggaact
     7741 gcggctgggg gccgccgggg agtacgcgcc ggaggtcgtc gaggccctgg ccagggttct
     7801 gtcccgggac acggagggga cgcgtgagca ggtggaccgg tcgtggtgag agggcggacc
     7861 gggcggtctg gttcccggcc gagctgggta acccatgggt aatgagcgcc ctcgcggccg
     7921 tacgtggttg gatgcgaagg agagggtgtc cgggggtgcc gatcgctgcg gccggcccac
     7981 cgaacggaac tggcaggcgg gaatcgtgag gatcttcggc aagggacgtc accggccctc
     8041 cgcctcctgg cggcaggcca cggaccgcgc gttcacgctc atcggcgacg gccggtacga
     8101 ggacgcgggc gcgctgctga cccgggccgc cgacctggag ccctggctgt cggagtcctg
     8161 gttcaacctc gcgctgctgc acaagttccg gcacgactgg gagcaggcgc gcgcggccgg
     8221 gctgcgcgcc gtcgccctgc tcgaccgcga caccggggcc ccggactggt ggaacgtggg
     8281 catcgcggcc accgccctcc aggactggcc gctggcccgc cgcgcctggc aggcgtacgg
     8341 gctgaaggtg cccggccccg cgaccgactc gggcgagccc ctcggcatgg acctgggcag
     8401 cgcggccgta cggctgtccc cggagggtga ggccgaggtg gtgtgggggc ggcggctcga
     8461 ccccgcccgc atcgaggtgc tgtccatccc cctgccgtcc tccgggcgcc gctggggcga
     8521 ggtcgtgctg cacgacgggg tgcctcacgg cgagcggagc accgccgccg ggcacaccta
     8581 cccggtgttc gacgagatcg agttgtgggc gccctcgccg gtgccgacct gggtggtgct
     8641 gctggaggcc gcgtccgagg ccgaccggga cgcgctggaa cagctcgcct ccgacgccgg
     8701 gttcgcggcc gaggactggt cgtcgtcggt gcggctgctg tgccggatgt gctcggagtc
     8761 gcggatgccg tcggacgagg gtgacgggga gcacctcgat ccacacgatc acagtgagcc
     8821 ggggcatccc gggccgttgg ggcatcggac ggacgggcag ttgtgggtgc cggagcggga
     8881 gtgcggcatc gctgccccgg cttctctggt tcgggggttg ttggacgggt gggttgctga
     8941 cagtccggac tctcgggact ggcgggatct cgaagaggtt tgttgaggct cgcggtcggc
     9001 tgcggggccg tggcggctga tcgcgcccac gcggcggaac cgcacgtcga cgctgccccg
     9061 cgccccttga aggagcgctg cacttaccct tgtcacagca gtctcggtca tctcaggaag
     9121 gcacacgtcg gtcatggctc agcaggacac cgatcagcag cacgcgggcg tgctccccgt
     9181 cgacgacgag ggctacgtca tcgacacgga ggactgcgag aagcgcgagg cggagtggcg
     9241 ggagcgcggc acctcgcgcc cgatcaccgt ggtcggcaac ccggtgctgc acaaggagtg
     9301 caaggacgtc acggacttcg gcgaggagtt ccagcagctc gtcgccgaca tgttcgccag
     9361 ccagcgcacc gccgagggcg tgggtctggc cgccaaccag atcggtgtcg acctgaaggt
     9421 cttcgtctac gactgccccg acgacgaggg tgtgcgccac gtcggcgtgg tctgcaaccc
     9481 caagctggtc gaactgcccg ccgagcggcg ccggctggac gacagcagcg agggctgcct
     9541 gtcggtgccc accgcgtacg cgccgctggc ccggcccgac tacgccgagg tgaccggtca
     9601 ggacgagaag ggcaacccga tccgggtacg cgggacgggg tacttcgcgc gctgcctcca
     9661 gcacgagacg gaccacctgt acggctacct gtacatcgac cgtctgtcga agcgcgagcg
     9721 taaggccgcg ctcaagcaga tggccgagaa cgagccgcgc taccccgtgg tcgccaacga
     9781 ctgaccgcct tcacggctcc cctcacatcc cgcgcacggc gcccgatccg gcacatcccg
     9841 gacgggcgcc gttcgtctgt gcgcatccaa aggtagtgaa agaagcaaat ccgttcccac
     9901 aacggtcagt tgtggtgctg aatggaggta cggggatacg cacggcgtac gcccggctcg
     9961 gggggcgggc gctcaactgg cggctgagag gggaatgttc gtgcatgctt tgtcacacgg
    10021 ctccacatcg acaccgacca ccatcgcagt tccaccggcg ctgtctcttc cggtgatcga
    10081 ggcggcgttt ccccggcgac tccacccgta ttggccgaag ctccagaggg agacccgggc
    10141 atggctgctc gaaaagcggc tcatgacccc ggagaaggtg gaggaatatg ccgacggcct
    10201 gtgctacacg gacctcatgg cgggctacta cctcggcgcg cccgacgagg tcctccaggc
    10261 gatagcggac tacagcgcct ggttcttcgt ctgggacgac cgtcacgatc gcgacatcgt
    10321 gcacggccgg cccgacgcct ggcggcggct gaaggacctg ctgcacagcg ccctcgaccg
    10381 ccccggtgac cacctgggtc accaggaccc cgtggtcgcg ggcctcgccg acagcgtgcg
    10441 gcggctccac gcattccttc cggacacctg gaacgcgcgg ttcgcgcgtc acttccacgc
    10501 cgtgatcgag gcgtacgacc gggagttcca caaccgcacc gaaggcgtcg tcccgaccgt
    10561 cgaggaatac ctcgaactgc gccgcctcac gttcgcgcac tggatctgga cggaccttct
    10621 ggaaccgagc gcggggtacg aactcccgga cgcggtgcgg aagaacccgg cctatcggaa
    10681 accggcgctg ctcagtcagg aattcgccgc ctggtacaac gacctctgtt cgctgcccaa
    10741 ggaaatcgcc gggaacgagg tgcacaatct cggcatcagt ctcgtcaccc acgagggaat
    10801 gaccctcgaa gaggcgatcg ctgacatacg gcgccgcgtc gaggaatgca tcagcgaatt
    10861 cctggacgcg gaacaggagg cattacggtt cgccgaccgg ctcgacgacg ggacggtggg
    10921 cggaaaggag acgagcgccg ccgtacgcgc ctgcgtcggc aacatgcgga actggttcag
    10981 ttccgtctac tggttccacc acgagtccgg ccggtaccgg gtcgacagct gggacgaccg
    11041 gtccacgccc ccgtacgtcg acaacgcaac ggaaggtgag aaatgaccgt cgagtccgta
    11101 cgcccggagg acaccgccgc gacggccgag ccgcccgtgg cgggcggtgc cgtcccgctc
    11161 ctcggtcacg gctggcgcct ggtgcgcgac ccgctggcct tcctgtccca gctgcgcgac
    11221 cacggtgacg tggtgcgcct gaaactgggt cccaagacgg tctacgccgt caccaccccc
    11281 gccctcaccg gagcggtggc gctcagcccg gactacatca tcgccgggcc cctgtgggag
    11341 tcgctggaga gcctgctcgg caaggagggc gtggccaccg ccaacggccc gctgcaccgc
    11401 cgccagcggc gcaccatcca gccggcgttc cggctcgacg cgatccccgc ctacggtccg
    11461 atcatggcgg aggaggccta cgcgctcgtg gagcgctggc gggacgcgga cggggtgctg
    11521 gacatcacgt acgagtcgtt ccgcgtggcc gtgcgggtcg ccgcccgctg cctgatgcgc
    11581 ggcggctaca tggacgccca cgccgaccgc atatgcgccg acctcaccac cctgttcgcg
    11641 gggatgtacc agcgcatggt ggtgccgctc ggaccgctct acaagattcc gcttccggcc
    11701 aatcgggaat tcaaccgcgc cctggccgat ttgcatgtcc tggtcgacga gatcgtggcc
    11761 gaccgacggg cgagcggtca aaagccggac gatttgctga cggctttgct ggaggcgaag
    11821 gacgacaatg gcgaccccat cggggagcag gagatccatg atcaggtcat cgccatcctg
    11881 acccccggcg cggaaaccgt cggttccacg atcatgtcgc tcctcctggt tctcaccgag
    11941 cacccggaac tcggcgacaa gatccgcgac gaggtgaaat ccgtggtcgg cgaccgcccg
    12001 gtcgcattcg aggacgtgcg gaagctgacg tacaccgcga atgtcgtcac ggagaccctg
    12061 cggctgtatc cggccgtctg gatattgacc cggcgcgcgg tcgccgacac ggaactcggc
    12121 ggttaccgca ttccgaaggg cgcggacctc atctacagcc cgttcgcggt ccagcgcgac
    12181 cggcggtcgt acgagcggaa cgaggacttc gacccggacc gctggctccc ggagcggtcg
    12241 aaggacgtgc ccaagtacgc gatgagcccg ttcagcgtgg gcaaccgcaa gtgccccagc
    12301 gaccacttct ccatggcgga gctcacgctc gtcaccgccg tggtcgccca cgcgtacggc
    12361 ttcgagcacg cgtcggactc cgatccccgg ccccgcatcg gcatcacgct gcggccccgc
    12421 cggctgatgc tgcgggcgct gccccgctga cgccccgccg accggcgcgc ggtcaggcgg
    12481 cctccgggcc cctgaacgcg cgccggtagg actgcggggt ggtccccacc gcgcgcacga
    12541 agtggtggcg cagcgcggcc gcgttgccga agccggcgcg gcccgcgatc gcgtccaccg
    12601 tctcgtccgt ccgctccagc agatgctggg cgagcagcac ccgctggcgc aggatccagc
    12661 ggtagggcgt ggtgccggtc tcctgctgga agcggcgggc gaaggtgcgc ggcgacatga
    12721 gggcgcgggc ggcgagctgc tcgacggtga cctcctcgtc gaggtgctgc tccatccaca
    12781 ccagcacccc ggcgaccgag tcgcccccgg gctccggcag cggacgttcg atgtactggg
    12841 cctgcccgcc gtcgcggtgc gggggcacca ccatccggcg ggcgatccgg ttggccacct
    12901 cagggccctg ttccttgcgc accaggtgca gacaggcgtc gatgcccgcg gcggtgcccg
    12961 ccgaggtgat caccgggtcc tcgtcgacgt agagcacgtc gggttcgacc gtcagatgcg
    13021 gatagcggcg gctcagctcc tccgcgtgct tccagtgcac cgcggcccgc cggccctcca
    13081 gcagcccggc ggcggccagc acgaacgccc cggagcacac gctcagcacc cgcgcgcccc
    13141 ggtccaccgc ccggcgcagc gcgtccagca tctcgggtgg gaactcccgg gaggtgtagg
    13201 aaacgccggc gggcacggtg atcaggtcgg ccgcgtccag ccggtccagg ccgtgctcgg
    13261 tctggagcgt gaaaccggcg ctggcgcgca ccgaggcccc ctccgcagag acgaccgcga
    13321 agtcgtacac cggcagcccg tcgtcgctgc ggtcgatgcc gaagacctcg cagaccacgc
    13381 cgagttcgaa cggattcacg ccgtcgagca ggacggccgc cacattccgg agcatggctc
    13441 cagtgtgcct cgccgttggc agtaaatcga gggtgcacga cagtcctgcc actcctcgta
    13501 aggagcgtcc ggcggcacag tggtgtccat gaacacgacg cagacagaag cactgatcgc
    13561 gatggtggcc gttctcggcc tgttcgtcct catggtcgcg cccgccgtga tcggcatcct
    13621 gcgcgaccgc cgcatcgacc ggcagatccg gcgggcccgg gccaccctgg tcaccgagcc
    13681 gcccggtatg ccggccgcgt cccggccgga gcaccgggcc gcctcccgcc gccacgcacg
    13741 cgcggcgtga gacggccccg gcgcgcgggc cctagaagtc ctcgtccagg tcgaccgtgc
    13801 cctccacggc gacctggtac gcggacggac ggcgttcgaa gaagttggtc agctcctgca
    13861 cgccctgcag ctccatgaac gagaacgggt tctccgagcc gtacaccggc gcgaagccca
    13921 gccgcaccag acgctggtcg gcgacgcact ccaggtactg ccgcatcgac gcggtgttca
    13981 tgccgggcag cccgtccccg cacaggtcac gggcgaactg cagctccgcc gcgacggcct
    14041 cgcggagcat gtcggtgacc tgccgcccga gctcctcgtc gaacagctcc ggctcctcct
    14101 tgcgcacggt gtccaccacg tcgaaggcga agctcatgtg catcgtctcg tcgcggaaca
    14161 cccagttggt gccggtcgcc agcccgtgca gcagaccccg gctgcggaac cagtagacgt
    14221 aggcgaaggc gccgtagaag aacagccctt cgatgcaggc cgcgaagcag atcaggttca
    14281 gcaggaagcg gcgccggtcg gcccgcgact ccagccggtc gatcttctcc accgagtcca
    14341 tccaccggaa gcagaactcg gccttctccc ggatggacgg gatgttctcc acggccgcga
    14401 aggccgccgc ccggtcgtcc ggatcgggca ggtaggtgtc cagcagggtc aggtagaact
    14461 ggacgtgcac ggcctcctcg aacagctgcc gtgacaggta cagccgcgcc tcgggcgagt
    14521 tgatgtgctt gtacagcgtc agcaccaggt tgttcgccac gatcgagtcg ccggtggcga
    14581 agaacgccac gagccggccg atcagatgct gctcctcggg cgtcagcttc gccaggtcgg
    14641 cgacgtccga gtgcaggtcc acctcctcga catgccaggt gttcttgatc gcgtcccggt
    14701 agcgctcgta gaagtccggg tagcgcatgg ggcgcagggt cagctcgaag ccggggtcga
    14761 gcaggttctt ggtcgtgctg gtggtcactg gcaggcctcg caggattcgg ggttctcgag
    14821 ggagcaggcg acggcctcgg ggtcggccgg ctgctggacg gggacgggta cggcggcgcg
    14881 ggccgcgcgg gcgatccggg tcgccggacg ggaacgcagg tagtaggtgg tcttcagccc
    14941 ctgcttccag gcgtaggcgt acatcgagga gagcttcccg atggtcggcg tctccaggaa
    15001 caggttgagc gactgcgcct ggtccaggaa cggggtccgg gcggcggcca tgtcgatcag
    15061 gccgcgctgc gggatctccc acgccgtgcg gtacagccgc cgtacgtctt ccgggatcca
    15121 cgcgaagtcc tgcaccgagc cgttcgcctc gcgcagcgcc tcacgggtgc gcgcgtccca
    15181 cacgcccagc cgcttgaggt cctccaccag gtacgagttg acctggagga actccccgga
    15241 cagcgtctcg cgcttgaaca ggttggacac ctgcggctcg atgcactcgt acacgcccgc
    15301 gatcgatgcg atggtcgcgg tgggcgcgat cgccagcagc agcgcgttgc gcaggcccgt
    15361 cgcggcgatc cgcgaccgca gtgcctccca gcgctccggc caggcgagct cgactccgta
    15421 gtggtcgggg tgcagcacgc cccgcgcggt gcgggtcttc tcccaggcgg gcagcggacc
    15481 gtgccgctcc gcgagaccgg cggacgtctc gtacgcggcg agcatgatgc gctcggcgat
    15541 ccgggtggac agcgccttcg cctcggggga gtcgaagggc acgcgcagtc ggaagaacac
    15601 gtcctgcagc cccatcacgc ccagacccac cgggcgccag cggctgttgg accgggacgc
    15661 ctccccggtc gggtagaagt tgatgtcgac cacccggtcc aggaacgtca cggcggtgcg
    15721 gaccgccgcg tccaggcgtt cccagtccat gccgtccggg cccgcgaagg ccgcgaggtt
    15781 gaccgagccg aggttgcaga ccgccgtctc gccgtcgtcg gtgacctcca ggatctccgt
    15841 gcacaggttg gaggagtgga cgacgtgacc cggttcggcg gtctggttgg cggtgcggtt
    15901 ggcggtgtcc ttgaaggtga tccagccgtt gccggtctgc gcgagggtgc gcatcatccg
    15961 gccgtacagc tcgcgcgccg gtagcgtcct gcgggccagg cccttcgcct cggcggctcg
    16021 gtaggccgcg tcgaactcct cgccccacag gtcgaccagc tcgggcacgt cgacggggga
    16081 gaacagcgac catggggcgt ctgcgtcgac ccggcgcatg aactcgtccg ggacccagtg
    16141 cgccaggttc agattgtgcg tacggcgggc gtcctcaccg gtgttgtcgc gcagctccag
    16201 aaactcctcg acgtccgcgt gccaggtctc caggtagacc gcggcggcgc ccttgcgccg
    16261 gccgccctgg ttcacggcgg cgaccgaggc gtccagcgtc ttcaggaacg ggacgatgcc
    16321 gttggagtgc ccgttggtgc cgcggatcag cgaaccccgg gcgcggacgc gggagaagga
    16381 cagaccgatg ccgccggcgt gcttcgagag gcgggcgacc tggtggtagc gctcgtagag
    16441 ggagtccagc tcgtccttgg gggagtccag gaggtagcag gacgacatct gcgggtggcg
    16501 ggtgccggag ttgaacagcg tgggggagga gggcaggtag tccagccggc tcatcagccc
    16561 gtacagcgcg gcgacgtcct ccagcgcccg ctcgctctcg tcctcggcga gcccgcaggc
    16621 cacccgcagc aggaagtgct ggggcgtctc gacgaccttg cgggtgaccg ggtggcgcag
    16681 caggtagcgg ctgtgcaggg tgcgcaggcc gaagtagccg aaccggtcgt cggcgtccgt
    16741 gtcgaccagc gcgtccagac gggccgcgtg gagccggacg aacgcggcgg tgcggtcgcc
    16801 gatcaggccc tcccggtgac cggcggccac cgagccggtg aacgaggtga cgccctgcga
    16861 ggcggcctcg gcgcggatgc cgagggtgag cagccgggcg gcgagccggg agtaggcggg
    16921 gtcctcggag atcagcccgg ccgccgcctc ggtggccagg tcccgcagct ccgcctcgtc
    16981 ggcggaggcg gaccggccgc gcagcgcggc cgcggccacc cggccggcgt cggcgtcggg
    17041 caggtcggcg gtcagctggg tcagggtccg cagcagcgcg gccccggggc cgtcactgtc
    17101 ctcggtcacg cgggtcgctg aagccggatc ggctggcgcg atggtcacgt gtggctctcc
    17161 ctcgctcggc acgggggcct cgaagagcgc agggggcagc acacgaacgc acgcggcgtc
    17221 gcgtccaccg gcccattccg cgaggcccgg acgtcagggc acccggaccg gaagggccgg
    17281 gcgcactgtc ggcaggtcct cggactgact cccgtgcgcg cccgtgggca ggcatgggta
    17341 caccgttgcg ggacagttcc ggattcgcac cggattcccc tgcggcgaca gcgagcatga
    17401 gcatacatct tgtgccgggt gtcgccgacg gacccatatg ttgtgtcgcg ctggggttat
    17461 ggtggggtcg gacggaaggg ctgcgcccgg ccgtcagagc gtcagttcgt agaccagcag
    17521 catgatgtcg tcgagctccg gcagcgggtt ccagtcccgc ccgggggccc gcgtgaagcc
    17581 cagccgctcg tacacccggt gcgcggagtg catcgtgcgc tgcgtggaca gcaccatgcg
    17641 ggtgcggccg agcgcccgcg cccggtcgac gcaggcgcgc accagggcct caccggcgcc
    17701 ccggccgcgg tgggcggggg agacggccag catccgtatc tccgcctcgc cgggctccgc
    17761 gatgtcggcc atgggcccgg ggccgggcac gaaggtcacc ccgcccagca gcgcgccgtc
    17821 cgccacggcg accagcacct cggcggccgc cgcccgcttg cccacgtccc gcagctcgtc
    17881 caggtaggag tcggactccc cgaagtccag cagcccgtcg ccgagatagg cctgagcggt
    17941 gatctcaccg aggtccgcgt gctcgccggg cgtcgccggc cggatgacga tgtccatgcg
    18001 ggggagtctg ccgcacgggc acgacagcgg gccgccggtt ttccaccggc ggcccgctgc
    18061 cctgtgcgtg aacggcgtca gtgcttgctg tccgccgtgg ccggcgggag ctccacctgc
    18121 acgcccgggt cgccggcgtc cgccgtgtag tcgcgcggct cggtctcgtc gacgccgtcc
    18181 ggcgccttga ccgcccgcat gacgaaggtc aggacgaccg tgaccagcac gttgatcacg
    18241 aaggcggtga gaccgatgta gccgatctcc ccgatgcccg ggatctcctt ggcggagccg
    18301 ccgaagtgct tctgcgtcgg cgacgccacc ccgtacgcgg cgaccgtgcc gtagatcatg
    18361 ccgaccgccc agccgccgat cagcgcccag cggtggaacc agcgggtgaa caggccgccc
    18421 accagcgccg ggaaggtctg caggatccag atgccgccca gcagctggaa gttgatcgcg
    18481 acggtcttgt ccatggtcag gacgaagacc agcgcgccca ccttcaccag cagggacacg
    18541 atcttggaga ccgcggtctc ctgcttgggc gtcgcgtccg gcttgatgaa gtccttgtag
    18601 atgttgcggg tgaacaggtt cgccgccgcg atcgacatga tcgccgccgg caccagcgcg
    18661 ccgatgccga tcgccgcgaa ggccaccccg gcgaaccagt ccgggaacat gttctcgaac
    18721 agctgcggga tggccagctg gccgttctgc accttcaccc cggccgcgat cgccatgaac
    18781 ccgagcagcg ccagcaggcc cagcatcagc gagtacagcg gcaggatcgt ggtgttgcgg
    18841 cggatcacct cacggctgcg cgaggacagc gtcgcggtga tcgagtgcgg gtacatgaac
    18901 agcgcgagcg ccgaccccag cgccagcgtg gcgtacgtcc actggcccgc ctcgcccggc
    18961 accagggcgc cgcgcggggc accggtggcc gggttggtct cgctgtacgc ctcctgcgcg
    19021 gaggcgaaga tctcgtcgaa cccgcccagt ttgatcggga tgtagatgat cgccaccgcg
    19081 atcacgatgt agatcagcgt gtccttgacg aacgcgatca gcgcgggcgc ccgcagcccc
    19141 gacgagtagg tgtacgcggc cagcacaccg aaggcgagga gcagcggcag gtccttgatg
    19201 aaccagttgg tgttctcgcc gccgccgacg cccatcacgt ccagcacggc ctggatgccg
    19261 accagttgca gcgcgatgta cggcatcgtc gccaggatgc cggtgaccgc gacggccagc
    19321 gacagcccct tcgagccgaa ccgcccgcgc acgaagtcgg acgtcgtcac atagccgtgc
    19381 ttgtgcgaca ccgaccacag ccggggcagg aaggtgaaga tcagcgggta cacgaggatc
    19441 gtgtacggca ccgcgaagaa gccggccgcg cccgccgcgt agatcgccgc cgggacggcc
    19501 acgaaggtgt acgcggtgta caggtcgccg ccgagcagga accaggtgac ccaggtgccg
    19561 aacgaccgcc cgcccaggcc ccattcgtcg agagtgtgct cgttggcggc cttgcgccag
    19621 cgtgcggcca ggaagcccat cacggtgacg agcacgaaga agaagatgaa gacggcgagt
    19681 gccacgccgt tcacgccgtc gttcactgct cggcaccacc cttcgcggcg gagcgggcgc
    19741 gctggtcacg ctgccagagc ttgtaggcga tcatcgtgag cgcggtcgag atcagcaccc
    19801 acagcatctg gtaccagtag aagaacggga tgccgatgaa caccgggtcg gtcttggcgt
    19861 aggacccgac ccacagcatg gcgacgaatg gtgcgagcag acagaggccg atgacgacgc
    19921 gcatgggcgt caccaccggc cctggtgttg tttgcggggt ttgcgacatc agacggctcc
    19981 cgtcccctca ctgatcgccg acgttggctc gcggcaatgt aggtgagggc gcggggcggt
    20041 cgtaacccct cgtaagaggg gcggtatgca gcagcagcgc aaccgcaagg caacagcaac
    20101 gaaaatcctg tcaaccgccc ggtctgtcgg gttttgcggt gacgtcggcg gctgtccgtc
    20161 agtcctgggg gcgcttgagg cgcgcgacga acttgtaccg gtcgccccgg tacaccgacc
    20221 gcacccactc cacgggctgc ccgccccggt ccagcgagtg ccgggacagc atcagcatcg
    20281 gcaggcccac gtcggtgccg agcaggcccg cctcgcgcgg cgtggccagg gacgtctcga
    20341 tggtctcctc ggcctccgcg agatggacgt cgtacacctc ggcgagggcc gtgtagagag
    20401 acgtgtactt ggtcaggctg cggcgcagcg ccgggaagcg cttggcgctg aggtgggtgg
    20461 tctcgatggc catgggctcg ccgttggcca tgcgcagccg ctcgatgcgc agcacgcggc
    20521 cgccggcggt gatgtcgagc agcccggcca gccggtcgtc ggccgtgatg tacccgaggt
    20581 cgaggagctg cgaggtcggc tccaggccct gcgcgcgcat gtcctcggtg tacgaggtga
    20641 gctggagcgc ctgggacacc ttgggcttgg cgacgaaggt gcccttgccc tggatgcgct
    20701 ccagacgtcc ctcgaccacc agttcctgga gcgcctggcg cacggtggtg cgggaggtgt
    20761 cgaactcggc cgccagcgtg cgctcgggcg ggaccggggt gccggggggc gccgtctcgg
    20821 tcatgtcgag cagatgcttc ttcagccggt agtacttagg cacgcgtgcc gtacggaccg
    20881 cggtcccacc ctcgttctcc gtactgctga cgtcggtgct catgctctgc cttcccggct
    20941 ccggctgccg aagcggccga cagaccgtcg gccacggctg acatcgtggc acggctccgg
    21001 gcgggggcgg gcccctcgcg cgctccgtga tcccttttgt atacccctgt gaccagtgat
    21061 ggtccagacc acgggcggtg gtcaga
//
