LOCUS       NZ_CP104794            22309 bp    DNA     linear   CON 09-JUL-2024
DEFINITION  Streptomyces sp. FZ201 chromosome, complete genome.
ACCESSION   NZ_CP104794
VERSION     NZ_CP104794.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. FZ201
  ORGANISM  Streptomyces sp. FZ201
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8604396)
  AUTHORS   Zhang,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2022) College of Life Science and Technology,
            Jinan University, Guangzhou, Guangzhou, Guangdong 510632, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2021
            Assembly Method                   :: unicycler v. 3.14.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 235.1x
            Sequencing Technology             :: Illumina NovaSeq6000; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025402955.1-RS_2024_07_09
            Annotation Date                   :: 07/09/2024 06:54:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,562
            CDSs (total)                      :: 7,471
            Genes (coding)                    :: 7,336
            CDSs (with protein)               :: 7,336
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 55 of 135
            Pseudo Genes (incomplete)         :: 92 of 135
            Pseudo Genes (internal stop)      :: 7 of 135
            Pseudo Genes (multiple problems)  :: 18 of 135
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:45:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6700787
            Orig. end                         :: 6723096
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP104794.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zhang Fei, College of Life
            Science and Technology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22309
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="butyrolactone"
                     /product="terpene"
                     /region_number="22"
                     /rules="AfsA"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22309
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="neighbouring"
                     /product="butyrolactone"
                     /product="terpene"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10915
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10915
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5915](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5915
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     gene            complement(114..1034)
                     /locus_tag="N6J21_RS30160"
     CDS             complement(114..1034)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034207.1"
                     /locus_tag="N6J21_RS30160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_261719742.1"
                     /transl_table=11
                     /translation="MTRIRARRAAALTAAPLLLALGAAGPAAAHGAPTDPVSRVRACSP
                     EGGADASTAACRAAVAANGAPFTAWDNLRIANVNGRDRQVVPDGKLCSGGLPAYRGLDL
                     ARSDWPSTRLEPGATLTMRYVSTIPHTGTFRLYLTEQGYDPAKPLTWSDLPERPFAEVR
                     DPALTDGAYRIRMTLPKDRTGRHVLYTVWRNSSTPDTYYSCSDVVFPEKETAAAKKPAE
                     SGKKASASAKPSPSPSKTPEASKTAQAEPRRTPVPPPTPAPDVSNVGANSTPDSGPSAP
                     LVAGGAAAVLVLTGGAALVARLRRR"
     cand_cluster    138..22309
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    138..22309
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10137:12309](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      10138..12309
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
     misc_feature    complement(1231..1247)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.7"
                     /tool="antismash"
     gene            1410..3212
                     /locus_tag="N6J21_RS30165"
     CDS             1410..3212
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122073.1"
                     /locus_tag="N6J21_RS30165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /protein_id="WP_176711775.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 7.1e-52, bitscore:
                     175.3, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTSPSVRRRLISVAAVSAALFTAATATGAMAQETAAPQQAPTAA
                     RTEAAPGAPAERLIVGYKSGAAEAKSNKAADADAVAKGRKAGESLDFERRLGTGAALVD
                     LGEDLSKADVADVIAEYEADPQVAYVVPDRLNKPLATPNDTEYTKQWDLFEATAGMNVP
                     GAWDTTTGTGVTVAVIDTGYVAHSDLAANIVGGYDFISDATVANDGGGRDSNPADPGDW
                     TAANECASGDPAYDSSWHGTHVAGTIAAATGNGKGVAGIAYGAKISPLRVLGKCGGYDS
                     DIIDAITWASGGTVSGVPANTNVAKVINMSLGGGGACTTATQNAINAAVGRGTTVVVAA
                     GNSNANAANYSPASCNNVISVAATDRQGNRSYYSNYGSVVDIAAPGGETNSVTTNGILS
                     TLNSGTKGPGSESYEYYQGTSMAAPHIAGLAALMKSANTALTPAQIESAIKTNSRALPG
                     TCSGGCGAGLADAAKTVQAVSGSGGSTGGTTFTSTSSVAIPDNGTVESPITVSGRSGNA
                     PSALQVGVDITHTYRGDLVIDLVAPDGSAYRLKNSSSSDSADNVVTTYTVNASGEAANG
                     TWKLRVRDTATLDTGRVNSWKLTF"
     gene            complement(3293..4159)
                     /locus_tag="N6J21_RS30170"
     CDS             complement(3293..4159)
                     /EC_number="1.6.5.2"
                     /GO_function="GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657054.1"
                     /locus_tag="N6J21_RS30170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_093720594.1"
                     /transl_table=11
                     /translation="MILLTGATGTVGSLAVRRLRGAAPLRLLTRRPDRAADLAGPGVEV
                     VGGDFDDPASLRRALTGVTSALLVTANPLTHAHDEHFLAAARACGVRHVVKLSALAVTD
                     PGATDLITTWQRGNEQLLADSGLLWTSLRPRAFMSNTLGWAISIRAEGVVRAACGNAVN
                     ATVDPRDIAEVAALTLLAPEAHAGRAYPLTGPEAISPVEQTKILGDLLQRPLVFEELTE
                     QEARRRLLVRYPAPIAEALAESASRGRAGAKSEVDPTVAELLGRPAGSYRQWALGRLDA
                     FRADAGT"
     gene            complement(4156..4824)
                     /locus_tag="N6J21_RS30175"
     CDS             complement(4156..4824)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1224: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122072.1"
                     /locus_tag="N6J21_RS30175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_093720593.1"
                     /transl_table=11
                     /translation="MAKQERAIRTRRAILEAAGAVFDEHGYASTTISMVLERAEVTKGA
                     LYFHFPSKESLAQAVLDEQVPFGAVPPQPCKLQEIVDMSFVYGRRLLNNPLLQGSVRLT
                     VDQATPPGVDHSGPFRQWADHVVELLEEADKQGELLPTVVPRDTVELLVGSFAGIQLMS
                     RALTGRADLGHRLSVMWAHVLPSIAVPGLIGRLDTAPDRGARILALLGEEDEPMRRAEP
                     "
     misc_feature    complement(4906..4919)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.49"
                     /tool="antismash"
     gene            5001..5915
                     /locus_tag="N6J21_RS30180"
     CDS             5001..5915
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657052.1"
                     /locus_tag="N6J21_RS30180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_093720592.1"
                     /sec_met_domain="AfsA (E-value: 1.1e-22, bitscore: 78.6,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQLPQLADFPTASEALTATVPRELVHRAAVAETLLTGWSRIGTD
                     RFRVTAQWPRAHQLHVSSDRTAYEPLLVTETVRQGGTLIAHTEYDVPLGHRFVLQELRV
                     STRPEHLRVGSLPAEPEVDISILDIRRRAGKVTAFDVEAAVFLENTQVGSAYFAASWTS
                     DPVYRRLRGGRTPQNVTPLPLPPGLAPEAVGRTVPGDVVLAPGDRRDRWQLRVDTAHPV
                     FFDHPLDHVPGMLLLEAAGQAARVAHGGRRVPMSFHATFDRYAELDLPTWIEVAPGPEG
                     LVQVLGVQGDSAVFACGVGTVAQ"
     gene            5989..6654
                     /locus_tag="N6J21_RS30185"
     CDS             5989..6654
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431986.1"
                     /locus_tag="N6J21_RS30185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_093720591.1"
                     /transl_table=11
                     /translation="MARQLRAEQTRATIITAAADLFDRRGYESTSLSDIVEHAQVTKGA
                     LYFHFAAKEDLAHAIMELQSQASRQIACEMESRGYSSLETLMRTMFGITRLSVEGPIPR
                     AGLRLATGPVPVKAPMQHPFAEWLDIATRKLVGAVKESDLHPDVDIDAAAHSLVCFFVG
                     TRIVGRSVEPVVRQPRRLAEMWHVLIRGMVPVPRRPRYLTLATQLEREVRLSQREAVG"
     misc_feature    6001..6003
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6673..7848
                     /locus_tag="N6J21_RS30190"
     CDS             6673..7848
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007505067.1"
                     /locus_tag="N6J21_RS30190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="damage-control phosphatase ARMT1 family protein"
                     /protein_id="WP_093720590.1"
                     /transl_table=11
                     /translation="MDDTPPVILGDAPGSFPHTVLTERHPAIIEQVRAAVPYGPGQRAA
                     LDALLHECTKGVVEPLPDGAHDRNRWQDWGIADHTGQPWTDAPWLWAESYFYRRLLEAT
                     GYFTSGAWQGIDPFRPAKLAELDSPETDEELAALDDLAALSPDERDRALLHGSLWGNRA
                     DLGFRLSTADGTSPSGTPPLVADDSGALWSLLPPGRTAPLLCLIADNAGRELVPDLLLI
                     AHLLDRGRVARAVLHVKPYPYFVSDATPADVLDAVRRLGQAPGAARAYGDTLWAALTDG
                     RLTIRAHPFSCAPLPYEEMPDDLRAELAGATVTILKGDLNYRRLVGDRRWPPTTPFSDV
                     TAYFPGPVAALRTLKSEVITGLDPDTVAALTAAEQESWRTSGSHALIQVRG"
     gene            complement(7853..9115)
                     /locus_tag="N6J21_RS30195"
     CDS             complement(7853..9115)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657049.1"
                     /locus_tag="N6J21_RS30195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_093720589.1"
                     /sec_met_domain="p450 (E-value: 4.7e-21, bitscore: 73.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVRPSPSAPDVFDPRQYAEGVPYAAYRVLRDHYPVSWQEEPEVL
                     GWPAGQGFWAVTRHADVVRVLKDALTYSSHLGATQIRDPDPEDLPFIRRMMLNQDPPQH
                     GRLRRLVSRAFTPKRIDRFTALAGKRARHLFAQALETAREQDGTVDLVTAVTDDYALLN
                     LADLLGVPERDRKLLLHWTQRVIGYQDPDESGPTVRDAAGRPVNPRSPAMLRDMFDYAG
                     ELAVYKRRYPADDVMTILAHDAELTAPELEMFFFLLTVAGNDTVRAAAPGGLLALAEHP
                     RWYARLRAEEVELDPAVDELLRWHPPVLTFRRTAAVDTELAGQPIRAGDKVVVFHASAN
                     RDERVFAEPDRLDPTRSPNPHVSFGDGPHVCLGAHFARLQLRVLYRESLRALPVLRTAG
                     PPVRLVSNFINGIKSLPVEVE"
     misc_feature    complement(8795..8797)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(9112..9963)
                     /locus_tag="N6J21_RS30200"
     CDS             complement(9112..9963)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-241). E-value:
                     9.1e-26. Score: 82.9. Matches aSDomain:
                     nrpspksdomains_N6J21_RS30200_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657048.1"
                     /locus_tag="N6J21_RS30200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_261719743.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5e-17, bitscore:
                     62.0, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 5.4e-18, bitscore: 64.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSFTLPHELHGDGAHKVFAVHGWFADRSAYASVLPDLDVLSFTY
                     ALVDLRGYGEAKDSAGAYTTAEAAQDLLELADRLGWERFSVVGHSMGGSVAQRLLALAP
                     ERLRRIVGVSPVPASGLPLPAEQWELFADAAHLPENRRAIIDFTTGGVRPAAWLERMVA
                     RSLAVSDPKAFRAWLDSWAGEDFHTEVAGARVPALALAGRLDPALSAGLLRETWRRWYP
                     YGEVRELAGAGHYAMDESPLELIQVVEAFLDADDEDDTDDLDELNDLDYADGSWAAEGE
                     QA"
     aSDomain        complement(9241..9903)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_N6J21_RS30200_Abhydrolase_1.1"
                     /evalue="9.10E-26"
                     /label="N6J21_RS30200_Abhydrolase_1.1"
                     /locus_tag="N6J21_RS30200"
                     /protein_end="241"
                     /protein_start="20"
                     /score="82.9"
                     /tool="antismash"
                     /translation="VHGWFADRSAYASVLPDLDVLSFTYALVDLRGYGEAKDSAGAYTT
                     AEAAQDLLELADRLGWERFSVVGHSMGGSVAQRLLALAPERLRRIVGVSPVPASGLPLP
                     AEQWELFADAAHLPENRRAIIDFTTGGVRPAAWLERMVARSLAVSDPKAFRAWLDSWAG
                     EDFHTEVAGARVPALALAGRLDPALSAGLLRETWRRWYPYGEVRELAGAGHYAMDESP"
     CDS_motif       complement(9748..9789)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_N6J21_RS30200_0001"
                     /evalue="3.40E+01"
                     /label="NRPS-te1"
                     /locus_tag="N6J21_RS30200"
                     /protein_end="72"
                     /protein_start="58"
                     /score="-2.7"
                     /tool="antismash"
                     /translation="SAGAYTTAEAAQDL"
     gene            10138..12309
                     /gene="cyc2"
                     /locus_tag="N6J21_RS30205"
     CDS             10138..12309
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675700.1"
                     /locus_tag="N6J21_RS30205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_261719744.1"
                     /sec_met_domain="T1TS (E-value: 1.5e-80, bitscore: 270.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQQPFELPHFYMPYPARLNPHVDEARAHSTAWAREMGMLEGSGI
                     WEQSDLEAHDYGLLCAYTHPECDGPALSLITDWYVWVFFFDDHFLDMYKRTQDRAAGKA
                     HLDRLALFMPMDPATAMPEPENPVEAGLADLWKRTVPAMSADWRRRFAVATEHLLNESM
                     WELSNINEGRIANPVEYIEMRRKVGGAPWSAGLVEYARAEVPAAVSGSRPMRVLMETFS
                     DAVHLRNDLFSYQREVEDEGELSNGVLVLETFFGCTTQEAADMVNDVLTSRLHQFEHTA
                     LTEVPALALEKGLTPDEIAAVAAYTQGLQDWQSGGHEWHMRSSRYMNERARTDRPWHGL
                     TGPGTSAADIGALLASAGSERLRAHTHVPYQQVGPSQIPDFYMPFPVELCPHLPGARQR
                     LVEWSHRMGILQEGVWDEDRLDAADLALCSAGLDPDATEEALDLSAHWLCWGTYGDDYY
                     PLVFGHRRDLAAAKLTTERLAACMPVDGGEVPFVPSNAMERALIDLWTRTTARMTPEQR
                     RTFKDAVNSMTESWLWELHNQFLNRVPDPVDYLEMRRSTFGSDLTMAMCRMGHGPAVPP
                     EVYRSGPVRSLENAAMDYGCLINDVFSYQKEVQYEGEVHNLILVVQNFFGCDYPAALAV
                     VHDLMTQRMQQFEHVVAHELPVVYDDFQLSEEARDAMATYVSDLQNWMAGILNWHREVD
                     RYKPDYLARRAHGFLPDRAPAAGVSVSLG"
     gene            complement(12314..13843)
                     /locus_tag="N6J21_RS30210"
     CDS             complement(12314..13843)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657046.1"
                     /locus_tag="N6J21_RS30210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_093720587.1"
                     /transl_table=11
                     /translation="MTDDALRTLRQNPRLADLAAFPFDFDLSRAEHGEPVRLASGAPIE
                     AVAGDGAGGTYFVCAGGPMLYADSEGRAGIIGSTADEALQVVLGLPCWFDFVDLSPGDG
                     AEVILARAAQALREDDRFEAARAELRAALGFPDRSPVELVALLHSALLRTEPDFVLLND
                     EEGGAYDLLDPHPRPPLWEPVLAQGRADLALLRTGDRADRDAVADDPVRRRLALRAAQF
                     DRAEGDGDWLRQLLRREAESSMTDELRLAAVLVGRYGDVADLPLLHEVRETDFDTHCGL
                     SEMPEPGADAAELLRWAEELDEWMFGSDPDDEPLSLWTGLALDQGMTELARVPLIRALD
                     EIFLDQSRLRRTDDPSRLDTSELSWLATELERAGDLGQALRARRLYASLQETAWDRISA
                     LRDQARLEREDGQLPRAVRSLASIRAILADPGDDSLTHWDRVNHSRFTVEEHYALTRAL
                     ADAGLIEEAGALLAAADAMLGGLSGQGLERLRELAEETAERVRDPRDVDPA"
     gene            complement(13929..14645)
                     /locus_tag="N6J21_RS30215"
     CDS             complement(13929..14645)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547157.1"
                     /locus_tag="N6J21_RS30215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_261719745.1"
                     /transl_table=11
                     /translation="MTEPLARVALVGDRSPNVVSHTRLPLLLDALADRERLLLDAYWVP
                     SWQAAAGPGAVDGFDAVWVVPGSPYRSEAGVLRAIRAAREGGIPFLGTCGGFQHTLLEY
                     AREVCGLTGAAHAENDPDAADPLIEPLACSLVGHEGAVLVEPDSLARSVIGAERTVERY
                     FCAYGATRHLDTLTAHGLRFSGHDEDGHVRIAELPDHPFFLASLFQPELSGDGSRPHPM
                     VTAWAKAAVERARGRR"
     gene            14734..15618
                     /locus_tag="N6J21_RS30220"
     CDS             14734..15618
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657044.1"
                     /locus_tag="N6J21_RS30220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_261720670.1"
                     /transl_table=11
                     /translation="MDPHLLRTYVTVARLASFSEAARALGYTQSAVSQHIAALEQDLGA
                     PLLTRRPVAPTEAGARLLEHAEPLLLRLDAARADVVRLAAAPPRGLTLAAAPTALGPAV
                     LAALPAAGVTLKVLPRDGVPAAVATGTADLGLVDGLAAPSDPLRMPDVAPLTTRGAGEE
                     PVCVLLPEAHPLARRPGLSLHDLVDARWLDAPGAGPPLDRLRAAVGGHGFRPALRYEGA
                     DVRALTALAAAGHGLTLLPRWAATGVPGAVAVPVTEPRIVHRTELVHAGALRGAAQELA
                     FALTSGEGPDFRS"
     gene            15742..16314
                     /locus_tag="N6J21_RS30225"
     CDS             15742..16314
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657043.1"
                     /locus_tag="N6J21_RS30225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PDZ domain-containing protein"
                     /protein_id="WP_261719746.1"
                     /transl_table=11
                     /translation="MEHTALRPKPMPGREPGDGPRTTPTPRPRAARRRGRRFTTALFAL
                     FVGAVLVLSGVGLGTVGATVIGMSKLAEAQQAQQASTRAHAAPSASLGPRPAPAATAAR
                     ATLGVEAVDAEKAGARLVGVHVPGPGYAAGLVRGDILLAFGRTRVDSATDLARAVAKAR
                     PGREVTLTVRHASGGYQQLVVVPGVVT"
     misc_feature    complement(16340..16355)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.4"
                     /tool="antismash"
     gene            16429..17553
                     /locus_tag="N6J21_RS30230"
     CDS             16429..17553
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996926.1"
                     /locus_tag="N6J21_RS30230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_250754757.1"
                     /transl_table=11
                     /translation="MSTPTPAPFTAEDYRARMERAARAAGDAGLAGLLVAPGPDLVWLT
                     GYAPPVTERLTLLVLVPGRDPELVVPALEAPDAAKAPCGPALALRDWTDGKDPYAVAAA
                     LLDPGGRFGISDNAWAMHLLGLTHTLPGSSYASLTEALPMLRAVKDAAELERLAAAGAA
                     ADATYEEIRRLPFAGRRESEVAADLARLLREHGHSQVDFTIVASGPNGADPHHEADERV
                     IERGDTVVLDFGGLLCGYGSDTSRTVHVGEPTEEERRVHDIVREAQEAGFRAVRPGVAC
                     QEIDRAARAVIEDAGYGEYFIHRTGHGIGVTTHEPPYMVEGEEQPLVPGMCFSVEPGIY
                     LPGRFGVRIEDIVTVTEDGGRRLNNTTREMAIVD"
     misc_feature    complement(17632..17644)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.92"
                     /tool="antismash"
     gene            17649..18596
                     /locus_tag="N6J21_RS30235"
     CDS             17649..18596
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996925.1"
                     /locus_tag="N6J21_RS30235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_093720582.1"
                     /sec_met_domain="APH (E-value: 2e-14, bitscore: 52.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPTPTADTVRRLVRSLLKDGADDTAGPEVRPVAPGDEAVTWW
                     VGARHVLRLAPDRDGTVRQRREMRLRDLVRPHLPVAVPTSVAHGEWAPGLAYTLDTKLP
                     GGSAEVHDVSAVGEADLAGLLTGLREVSVRQAEAIGVPRTGPRSLEALRRAAERAAARL
                     AEADEFDPARLHQLTPPAAVQLAAQPGTAVLVHHGLTGEHLVVSADGRVRGVLGWTDAV
                     VGDPAEDIAGLARAVGSPAAVRAATLAGYGARPCLRGLWLARCDTVIHLAEALDRPGRT
                     PLPELRRRLELAWEAILLERVTELREDDDPDEGP"
     gene            18765..19973
                     /locus_tag="N6J21_RS30240"
     CDS             18765..19973
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059024.1"
                     /locus_tag="N6J21_RS30240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_261719747.1"
                     /transl_table=11
                     /translation="MTQQVKRAFKYRIYPTDEQAAELSRTFGCVRLVYNKALEERTRAW
                     YGEQRRISYVQSSAALTEWKKTEDLAFLTEVSSVPLQQALRHLQTAFGNFFAKRAKYPR
                     FKSRKKSRASAEYTRSAFKWRDGELTLAKMTEPLDIRWSRPLPEGAVPTTVTVSRDAAG
                     RWFVSLLCEDTITPAPATTAAVGIDAGITSLVTLSTGEKIANPRHERRDRARLARAQRE
                     LSRKAKGSANQEKARRRVAKVHARIADRRRDFLHKLSTRLVRENQTVVIEDLTVRNLLK
                     NGKLARAISDAAWTDLRMMLEYKCAWYGRELVVTDRWFPSSKLCGACGTVAARMPLNVR
                     EWTCDCGVVHDRDVNAARNILAAGLAASACGDGVRPHRESSRTGRSSVKQESQRATAGI
                     PRL"
     gene            complement(19987..21732)
                     /gene="treZ"
                     /locus_tag="N6J21_RS30245"
     CDS             complement(19987..21732)
                     /EC_number="3.2.1.141"
                     /GO_function="GO:0033942 -
                     4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034231.1"
                     /locus_tag="N6J21_RS30245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_261719748.1"
                     /sec_met_domain="CBM_48 (E-value: 0.00012, bitscore: 21.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 1.2e-11, bitscore:
                     43.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFEVWAPQADRVTLHHGDATRALERDPEREGWWQGEAEAEDGTR
                     YGFALDDGPVLPDPRSRRQPDGPDGLSAVVDHGAYTWRADWAGRPLPGAVLYELHVGTY
                     TPEGTLDAAAERLGHLVELGVTHVELMPVCPFPGRHGWGYEGVSLWAVHEPYGGPAALK
                     RFVDRAHELGLGVVLDVVHNHLGPSGNYLPAFGPYFTETHHTPWGAAVNLDAPGSDEVR
                     AYLAGSALAWLRDYRIDGLRLDAVHALRDTRACHFLEELSAAVDTLAAETGRPLFLIAE
                     SDLNDPRIITPRAEGGLGLQAQWNDDFHHALHTALTGESQGYYADFARAPLAAVAKTLT
                     GGYFHDGTYSSFRGRHHGRPLDRSRVAGHRLLGYSQTHDQVGNRAQGDRLSAALSPGLL
                     ACAATLVLTAPFTPMLFMGEEWAAGTPWQFFTDHTDPELAEAVRRGRRREFAAHGWAEE
                     DVPDPQDPATRDRSCLDWSEPEREPHARVLDWYRRLIALRHEQPDLTDPDLADTKVAFD
                     ERHRWLAFRRGDVRVAVNLGKDPAQIPLGPRHARVLAAWEPVEVPGRDGVLHLPGESGV
                     VLLQD"
ORIGIN
        1 aggtctccgg ctcctcgctc tgcttcgcga acggatactt caccgccaag tacgccccgg
       61 tgaccgacgg cggagccccc gtcttcgtca actgacggac gccgcgcctg agttcacctc
      121 cttcgcaggc gcgcgaccag ggcggcgccc ccggtgagca ccagcaccgc ggcggcgccg
      181 cccgccacca gcggggcgga cgggccggag tccggcgtgg agttcgcgcc cacgttgctg
      241 acgtccgggg ccggagtcgg cggcggcacg ggcgtacggc gcggctcggc ctgcgccgtc
      301 ttcgaagcct ccggagtctt cgagggcgag ggcgagggct tcgccgaggc cgacgccttc
      361 ttcccgctct cggcgggctt cttggcagcc gccgtctcct tctccgggaa caccacgtcc
      421 gagcaggagt aatacgtgtc cggggtactg ctgttccgcc acaccgtgta cagcacatgc
      481 cgtcccgtgc ggtccttcgg cagggtcata cggatgcggt aggcgccgtc cgtgagtgcc
      541 gggtcgcgta cctcggcgaa gggcctctcc ggcaggtcgg accaggtgag cggcttggcc
      601 ggatcgtagc cctgctctgt gagatagagc cggaacgtac cggtgtgcgg gatcgtcgag
      661 acgtaccgca tggtcagcgt ggcgccgggc tccagacggg tcgagggcca gtcggagcgg
      721 gccaggtcca ggccccggta ggcgggcagg ccgccgctgc acagctttcc gtcggggacg
      781 acctgccggt cacgtccgtt cacattcgcg atgcgcaggt tgtcccaggc cgtgaagggt
      841 gccccgttcg cggcgacggc cgcccggcac gccgccgtcg aggcgtcggc gccgccctcc
      901 ggggagcagg cccgcacccg gctcaccgga tccgtgggcg cgccgtgcgc ggcggccggt
      961 ccggccgccc ccagggcgag cagcagcggg gccgccgtga gagcggcggc gcgccgggcg
     1021 cgaatccggg tcatgtgaag cgtctcctcg gccggtgcgg gacgggcggt gcgggaccgc
     1081 gtgcttctgt ccagtacggg ccgcgggccg tgtgcgttca gcggggtgcg agcccctgca
     1141 taagcagaca caagcggtca atcagtggat gccgagggtt tgtttccggc ctgatcgagg
     1201 gtttcccctg tatccctatg accgcccgct tgcctatcgt tcctgcacag ccgacccaca
     1261 ggtaaccccg caggggtcgg tccccaccgc gcctggccgg cctcagcgca acgcttttcg
     1321 gttctcggtt cacccccctc cgcttcgacg acgaagcgac agaccgccgc tccgacgctg
     1381 cccggagtcc ggccacgaaa ggcattccct tgcgtacctc cccctccgtg cgacggagac
     1441 tgatatccgt cgccgcggtc tccgccgcgc tgttcacggc cgctaccgcc accggcgcca
     1501 tggcccagga gaccgccgcc ccccagcaag cccccaccgc cgcccgcacc gaggccgccc
     1561 ccggcgcccc ggccgagcgt ctgatcgtcg gctacaagtc cggcgccgcc gaggcgaagt
     1621 ccaacaaggc cgccgacgcg gacgccgtcg ccaagggcag gaaggccggc gagtccctgg
     1681 acttcgagcg ccgcctcggc accggcgccg ccctcgtcga cctcggcgag gacctcagca
     1741 aggccgatgt cgccgacgtc atcgccgagt acgaggccga cccgcaggtc gcctacgtcg
     1801 taccggaccg gctgaacaag ccgctggcca cgccgaacga caccgagtac accaagcagt
     1861 gggacctgtt cgaggccacc gcgggcatga acgtgccggg cgcctgggac accaccaccg
     1921 gcaccggcgt gaccgtcgcc gtcatcgaca ccggctacgt cgcccactcc gacctcgccg
     1981 cgaacatcgt cggcggctac gacttcatct ccgacgccac cgtcgccaac gacggcggcg
     2041 gacgcgacag caacccggcc gacccgggcg actggaccgc cgcgaacgag tgcgcctccg
     2101 gcgacccggc ctacgactcc tcctggcacg gtacgcatgt cgcgggcacc atcgccgcgg
     2161 ccaccggcaa cggcaagggc gtcgccggta tcgcgtacgg cgcgaagatc tccccgctgc
     2221 gggtgctcgg caagtgcggc ggctacgact ccgacatcat cgacgccatc acctgggcgt
     2281 ccggcggcac cgtctccggc gtcccggcca acaccaatgt cgccaaggtc atcaacatga
     2341 gcctcggcgg cggcggcgcc tgcaccaccg cgacccagaa cgcgatcaac gcggccgtcg
     2401 gccgtggcac cacggtcgtc gtcgcggcgg gcaacagcaa cgccaacgcg gccaactact
     2461 cgccggccag ctgcaacaac gtgatcagcg tcgcggccac cgaccggcag ggcaaccgct
     2521 cctactactc caactacggc tccgtcgtcg acatcgccgc ccccggcggt gagaccaact
     2581 ccgtcacgac caacggaatc ctgtcgacgc tgaactccgg taccaagggc ccgggttcgg
     2641 agagctacga gtactaccag ggcaccagca tggccgcccc gcacatcgcg ggtctcgccg
     2701 cgctgatgaa gtcggccaac accgcgctca ccccggccca gatcgagtcc gcgatcaaga
     2761 ccaactcgcg tgctctgccg gggacgtgct cgggcggctg cggcgcgggc ctcgcggacg
     2821 cggcgaagac ggtgcaggcg gtgagcgggt ccggcggctc cacggggggc accaccttca
     2881 ccagcacctc gtcggtggcg atcccggaca acggcacggt cgagtccccg atcaccgttt
     2941 ccggccgcag tggaaacgcc ccctcggcgc tccaggtcgg cgtggacatc acccacacct
     3001 accgcggtga cctggtgatc gacctcgtcg ccccggacgg ttcggcctac cggctgaaga
     3061 actccagctc ctcggactcc gcggacaatg tggtcaccac ctacacggtg aacgcctccg
     3121 gcgaggccgc caacggcacc tggaagctgc gggtgcggga cacggcgacg ctggacacgg
     3181 gccgggtcaa cagctggaag ctgaccttct gaccgaagga cagccggaag gcgagtcctt
     3241 cacatgagcg ggcgggtcgg ccggtgcgga tggggcatcg gccggcccgt cgtcatgtgc
     3301 cggcgtcggc gcggaaggcg tccagtcggc ccagcgccca ctgccggtag ctcccggcgg
     3361 gccgccccag cagctcggcg acggtcgggt ccacctccga cttcgccccg gcccggcccc
     3421 gggacgcgct ctcggcgagc gcctcggcga tcggcgcggg atagcgcacg agcaaccggc
     3481 gccgcgcctc ttgttcggtc aactcctcga agaccaaagg gcgttggagc agatcaccga
     3541 ggatcttcgt ctgctccacg gggctgatcg cctccggccc ggtgagcggg taggcccgcc
     3601 cggcgtgcgc ctcgggcgcc aggagcgtca gggccgccac ctccgcgatg tcccgggggt
     3661 cgacggtggc gttgacagcg ttgccgcagg cggcccgtac gacaccctcc gcgcggatgg
     3721 agatggccca gccgagcgtg ttggacatga aggcgcgcgg ccgcagcgac gtccacaaca
     3781 gcccggaatc ggccagcagt tgctcattgc cgcgctgcca ggtcgtgatc aggtcggtgg
     3841 cgcccgggtc ggtgaccgcg agcgcggaca gcttcaccac atggcggacc ccgcacgcgc
     3901 gcgccgccgc caggaagtgc tcgtcatggg cgtgcgtgag cgggttggcg gtgaccagca
     3961 gcgcggaggt caccccggtc agcgcccggc gcagactcgc cggatcgtcg aagtcgccgc
     4021 ccaccacctc cacccccggt ccggccaggt ccgcggcccg gtcggggcgg cgggtcagca
     4081 gccgcagcgg agcggcaccg cgcagccggc gcacggcgag cgagccgacg gtgccggtcg
     4141 cgccggtgag caggatcatg gttcggccct ccgcatcggc tcgtcctcct cgccgagcag
     4201 ggcgaggatg cgcgcacccc ggtccggcgc ggtgtcgagc ctgccgatca gccccggcac
     4261 cgcgatgctc ggcaggacgt gcgcccacat caccgacagc cggtggccga gatccgcccg
     4321 cccggtcagc gcccgcgaca tcaactggat cccggcgaac gagccgacca gcagctccac
     4381 cgtgtcccgc ggcaccaccg tgggcagcaa ctcaccctgc ttgtcggcct cttcgagcag
     4441 ttccacgaca tggtccgccc actgccggaa cggcccggag tggtcgacac cgggcggggt
     4501 ggcctggtcc acggtgagcc gcacactgcc ctgcagcaga gggttgttca gcagccgccg
     4561 cccgtagacg aagctcatgt ccacgatctc ctggagcttg cagggctgcg gcggcaccgc
     4621 gccgaacggc acctgctcgt ccaggacggc ctgggcgagg gactccttgg aggggaagtg
     4681 gaagtacagg gcgcccttgg tgacttcggc ccgctccagc accatggaga tcgtcgtcga
     4741 ggcgtagccg tgctcgtcga acaccgcccc cgcggcttcc aggatcgctc tgcgcgtcct
     4801 gatggcgcgt tcctgcttcg ccataagggc ccctccgttg cgccgagttg acgggatggc
     4861 catggtgcga gggcccggag gcgcacccgg tcctggtcac cctggtctca ttgaaaacaa
     4921 accggtcggc tcgtactcta gcgctcacgg cacgggcacc tcgccgtctg tcaacactgt
     4981 cgggggagcc agggagagac atgcctcaat tgccgcaact cgccgatttc ccgacggcgt
     5041 ccgaggcgct cacggccacc gttccccgcg agctggtcca ccgcgcggcc gtcgccgaga
     5101 ccctcctgac cggctggagc cgcatcggga ccgaccggtt cagggtgacc gcgcagtggc
     5161 cgcgagccca ccagttgcat gtgtcgagcg accgtaccgc atacgagccg ctgctcgtca
     5221 ccgaaacagt ccgccagggc ggcaccctga tcgcgcacac cgagtacgac gtaccgctgg
     5281 gccaccggtt cgtgctccag gagctgcgcg tcagtacccg tcccgagcac ctccgggtgg
     5341 gctccctgcc cgccgaaccg gaggtcgaca tcagcatcct cgacatccgc aggcgggccg
     5401 ggaaggtcac cgccttcgac gtcgaagcgg ccgttttcct ggagaacacg caggtcggga
     5461 gcgcgtactt cgccgcgtcc tggaccagcg accccgtcta ccgcaggctg cgcggcggcc
     5521 gtacgccgca gaacgtcacc ccgctgcccc tgccgccggg gctcgcgccc gaggccgtcg
     5581 gccgcacggt ccccggcgat gtcgtgctgg ctcccggtga ccgccgggac cgctggcagc
     5641 tgcgagtgga taccgcgcat cccgtttttt tcgaccatcc tctcgaccat gtgccgggga
     5701 tgctgctcct ggaggcggcc ggtcaggcgg cccgggtcgc gcacggcggg cggcgcgtcc
     5761 cgatgtcgtt ccacgcgacc ttcgaccggt atgccgaact ggacctgccc acgtggatag
     5821 aggtggcgcc cggccccgag gggctggtcc aagtcctcgg tgtgcagggg gactcggcag
     5881 tcttcgcatg cggggtaggc acggtcgcgc agtgagctat ggtgttcggg gagcagaaaa
     5941 caaacggcat gacccgttct tttcccggcc caggagagag tcgagccgat ggcgaggcag
     6001 ttacgcgcag aacagacccg cgcgacgatc atcaccgctg ccgctgacct gttcgatcgt
     6061 cgcggctacg agtcgaccag tctgagcgac atcgtcgaac acgcccaagt caccaagggc
     6121 gccctgtact tccacttcgc ggcgaaggag gacctcgccc acgcgatcat ggagctgcag
     6181 tcccaggcgt cccgtcagat cgcctgcgag atggagtcgc gcggctactc ctccctggag
     6241 acgctgatgc gcaccatgtt cggcatcacc cggctgtcgg tggagggccc gatcccgcgg
     6301 gccggactcc ggctggccac cgggccggtc ccggtgaagg cgccgatgca gcacccgttc
     6361 gcggagtggc tggacatcgc cacccgcaaa ctcgtcggcg cggtcaagga gtcggacctc
     6421 catccggacg tcgacatcga cgcggcggcc cactccctgg tctgcttctt cgtcggcacc
     6481 cgcattgtcg gccgctccgt cgagccggtc gtccgccagc cccgcaggct cgccgagatg
     6541 tggcacgtcc tgatccgcgg catggtcccg gtgccccgcc gcccccgcta cctcaccctc
     6601 gccacccagc tggaacggga ggtgcggctg agtcagcggg aagccgtcgg gtgaccgcga
     6661 tacggtcgcc gcatggacga caccccgccc gtgatcctcg gcgacgcacc cggctccttc
     6721 ccgcacaccg tgctgaccga gcggcacccc gcgatcatcg agcaggtgcg cgcggcggtc
     6781 ccgtacggcc ccgggcagcg cgccgcactc gacgcgctgc tgcacgagtg caccaagggc
     6841 gtcgtcgaac cgctccccga cggcgcccac gaccggaacc ggtggcagga ctggggcatc
     6901 gccgaccaca cgggccaacc ctggaccgac gccccctggc tgtgggcgga gagctacttc
     6961 taccgccggc tcctcgaagc caccggctac ttcacctccg gcgcctggca gggcatcgac
     7021 cccttccgcc ccgccaagct ggccgagctg gactccccgg agacggacga ggaactggcc
     7081 gcgctggacg acctcgccgc actgtcgccc gacgagcggg accgggccct gctgcacggc
     7141 tccctgtggg gcaaccgcgc cgacctcggc ttccggctct ccaccgccga cggtacgagc
     7201 ccctccggca cccctccgct ggtcgccgac gacagcggcg ccctgtggtc cctgctgccg
     7261 cccggccgga ccgccccgct gctctgtctg atcgccgaca acgcgggccg cgaactcgtc
     7321 cccgacctcc tgctgatcgc ccatctcctc gaccgggggc gggtggcgcg cgccgtcctg
     7381 cacgtcaagc cttacccgta cttcgtctcc gacgcgaccc ccgccgacgt cctcgacgcc
     7441 gtgcggcggc tcgggcaggc gccgggcgcg gcacgggcgt acggcgacac cctgtgggcg
     7501 gcgctcaccg acggacggct cacgatccgc gcccacccct tctcctgcgc gcccctgccc
     7561 tacgaggaga tgcccgacga cctgcgcgcg gaactggcag gggccacggt cacgatcctc
     7621 aagggcgacc tcaactaccg tcgcctggtg ggcgaccgcc gctggccccc gaccaccccc
     7681 ttctccgacg tcaccgccta cttccccggc cccgtggctg ccctgcgcac cctcaagtcc
     7741 gaggtgatca ccggcctcga cccggacacg gtggccgccc tgaccgccgc ggagcaggag
     7801 agctggcgca ccagcggcag ccacgccctg atccaggtgc gtggctgaac gctcactcca
     7861 cctcgaccgg cagcgacttg atgccgttga tgaagttcga caccagccgc acgggcggac
     7921 cggcggtgcg caggaccggc agggcccgca gcgactcccg gtacagcacc cgcagttgga
     7981 gccgcgcgaa gtgcgcgccc aggcagacgt gcggaccgtc gccgaaggag acgtgcgggt
     8041 tcggggaacg ggtcgggtcg agccggtccg gctccgcgaa cacccgctcg tcgcggttgg
     8101 cggaggcgtg gaagaccacg accttgtccc cggcccggat tggctgcccg gccagctcgg
     8161 tgtcgacggc ggcggtccgg cggaaggtca gcaccggcgg gtgccagcgc agcaactcgt
     8221 ccaccgccgg gtccagttcg acctcctccg cgcgcagtcg cgcgtaccac cgcgggtgct
     8281 cggccagcgc cagcagaccg cccggggcgg cggcgcgcac ggtatcgttg cccgcgaccg
     8341 tgagcaggaa gaagaacatc tccagctcgg gggcggtcag ttcggcgtcg tgcgcgagga
     8401 tggtcatcac gtcgtcggcc gggtaccgcc gcttgtagac ggccagttca ccggcgtagt
     8461 cgaacatgtc ccgcagcatc gccggggagc gcggattgac cggccggccc gccgcgtcgc
     8521 gcaccgtcgg cccggactcg tcgggatcct ggtagccgat cacccgctgc gtccagtgca
     8581 gcagcagttt gcggtcgcgt tccgggacgc ccagcagatc ggccagattg agcagggcgt
     8641 agtcgtcggt gacggcggtg accagatcga cggtgccgtc ctgctcccgg gcggtctcca
     8701 gggcctgcgc gaacaggtgc cgggcgcgct tcccggcgag cgcggtgaac cggtcgatgc
     8761 gcttcggggt gaacgcccgg ctcaccaggc ggcgtaacct gccgtgctga ggcgggtcct
     8821 gattgagcat catgcgccgg atgaacggca ggtcctccgg atcggggtcg cggatctggg
     8881 tggcgcccag gtgggaggag tacgtcagcg cgtccttcag cacccgcacc acgtccgcgt
     8941 gccgggtcac cgcccagaac ccctgcccgg caggccagcc cagcacctcg ggctcctcct
     9001 gccaggacac ggggtagtgg tcgcgcagga cgcggtaggc ggcgtagggc acgccttcgg
     9061 cgtactgccg gggatcgaag acatcggggg cggacgggga cggccggacg gtcacgcctg
     9121 ctcaccctcg gccgcccagg acccgtccgc gtagtccagg tcgttcaact cgtccaggtc
     9181 gtcggtgtcg tcctcgtcgt ccgcgtccag gaacgcctcc accacctgga tcagctccag
     9241 cggggactcg tccatggcgt agtgcccggc cccggcgagc tcccgcacct cgccgtacgg
     9301 gtaccagcgc cgccaggtct cccgcagcag gcccgccgac agcgcgggat cgagccgccc
     9361 cgccaaggcc agggcgggca cccgggcacc cgccacctcg gtgtggaagt cctccccggc
     9421 ccaggagtcc agccaggccc ggaacgcctt cgggtcgctc accgccagcg aacgggccac
     9481 catgcgctcc agccaggccg cgggccgcac cccgcccgtg gtgaagtcga tgatcgcgcg
     9541 gcggttctcc ggcaggtgcg ccgcgtccgc gaacagctcc cactgctccg ccgggagcgg
     9601 cagccccgag gcgggcaccg gggagacccc cacgatccgc cgcagccgct cgggcgccag
     9661 cgccagcagc cgctgggcga ccgagccgcc catcgagtgc ccgacgaccg agaaacgctc
     9721 ccagccgagc cggtcggcca gctccagcag atcctgggcc gcctcggccg tcgtatacgc
     9781 ccccgccgag tccttcgcct cgccgtaccc gcgcagatcg accagcgcgt aggtgaagga
     9841 caggacgtcg aggtccggca ggacgctcgc gtacgccgac cggtccgcga accagccgtg
     9901 caccgcgaac accttgtggg caccgtcgcc gtgcagctca tgggggagcg tgaaggaggt
     9961 catgcgaaca cggtggcgcc accgccgggc ctcggcaaga gcacccggcg cggcggaccg
    10021 taaccggaac accacagtac gcatgcggag ttggccggtt tccgtcggtt tcacgcgatg
    10081 gtgtgatcat gtcccggcgt acggatgccc gcccggggcc ccgggtagtg cccggccatg
    10141 acgcagcagc ccttcgaact cccgcacttc tacatgccgt atcccgcgcg gctcaacccg
    10201 cacgtcgacg aggcccgggc ccactcgacg gcgtgggcgc gcgagatggg catgctggag
    10261 ggctccggga tctgggagca gtccgacctc gaagcacacg actacggcct gctctgcgcc
    10321 tacacccatc ccgagtgcga cggccccgcc ctgtcgctga tcaccgactg gtacgtgtgg
    10381 gtcttcttct tcgacgacca cttcctggac atgtacaagc ggacccagga ccgcgccgcc
    10441 ggcaaggccc acctcgaccg gctcgccctg ttcatgccga tggacccggc caccgcgatg
    10501 cccgagccgg agaacccggt ggaggccgga ctcgccgacc tgtggaagcg caccgtcccg
    10561 gccatgtccg ccgactggcg ccgccgcttc gccgtcgcca ccgagcacct gctcaacgag
    10621 tcgatgtggg agctgtccaa catcaacgag gggcggatcg ccaaccccgt cgagtacatc
    10681 gagatgcgcc gcaaggtggg cggcgccccc tggtccgccg gtctggtgga gtacgcgcgg
    10741 gccgaggtgc ccgccgccgt ctccggctcc cggccgatgc gggtgctgat ggagaccttc
    10801 tccgacgccg tgcacctgcg caacgacctc ttctcctacc agcgcgaggt ggaggacgag
    10861 ggcgaactca gcaacggcgt cctggtcctg gagaccttct tcggctgcac cacccaggag
    10921 gcggccgaca tggtgaacga cgtcctcacc tcccggctcc accagttcga gcacaccgcc
    10981 ctcaccgagg tccccgccct cgccctggag aagggcctga ccccggacga gatcgccgct
    11041 gtcgccgcct acacccaggg cctgcaggac tggcagtccg gcggccacga atggcacatg
    11101 cgctccagcc ggtacatgaa cgagcgcgcc cgcaccgacc ggccctggca cggactcacc
    11161 ggccccggca cctccgccgc cgacatcggc gccctgctcg cctccgccgg ctccgaacgc
    11221 ctgcgcgccc acacccatgt gccctaccag caggtcgggc cgtcccagat ccccgacttc
    11281 tacatgccct tcccggtgga gctgtgcccg catctgccgg gcgcccggca gcggctcgtg
    11341 gagtggtcgc accgcatggg catcctgcag gagggcgtct gggacgagga ccggctcgac
    11401 gccgccgatc tcgcgctgtg ctcggcgggc ctggaccccg acgccaccga ggaggccctc
    11461 gacctcagcg cccactggct ctgctggggc acctacggcg acgactacta ccccctcgtc
    11521 ttcggtcacc gccgcgacct ggccgccgcc aagctcacca ccgagcggct ggccgcctgt
    11581 atgcccgtcg acggcgggga ggtccccttc gtcccgtcca acgccatgga acgcgcgctg
    11641 atcgacctgt ggacccgcac gacggcgagg atgacgcccg aacagcggcg caccttcaag
    11701 gacgcggtca actccatgac cgagagctgg ctgtgggagc tgcacaacca gttcctcaac
    11761 cgcgtcccgg acccggtgga ctacctggag atgcgccggt ccaccttcgg ctccgacctc
    11821 accatggcga tgtgccgcat gggccacggt ccggcggtgc ccccggaggt gtaccgcagc
    11881 ggcccggtgc gctccctgga gaacgccgcc atggactacg gctgcctcat caacgacgtc
    11941 ttctcgtacc agaaggaggt ccagtacgag ggcgaggtgc acaacctcat cctcgtcgtg
    12001 cagaacttct tcggctgcga ctaccccgcc gcgctcgccg tcgtgcacga cctgatgacc
    12061 cagcggatgc agcagttcga acacgtcgtc gcgcacgaac tgcccgtggt gtacgacgac
    12121 ttccagctct ccgaggaagc acgcgacgcg atggccacct acgtcagcga tctgcagaac
    12181 tggatggcgg gcatcctgaa ctggcaccgc gaggtcgacc gctacaagcc cgactacctg
    12241 gcccgccgcg cccacggctt cctgcccgac cgggcaccgg cggcgggggt gtcggtgtcc
    12301 ctgggctgag tgctcaggcc ggatcgacgt cccgggggtc ccggacccgt tcggcggtct
    12361 cctcggcgag ctctcgcagg cgctccagtc cctgccccga gagcccgccg agcatcgcgt
    12421 ccgccgcggc gagcagtgcg ccggcctcct cgatgagacc ggcgtcggcg agggcccggg
    12481 tgagggcgta gtgctcctcg acggtgaacc ggctgtggtt gacgcggtcc cagtgcgtca
    12541 gggagtcgtc gccggggtcg gccaggatgg cgcgtatcga ggccagcgag cgcacggctc
    12601 gcgggagttg cccgtcctcc cgctccagcc gggcctggtc gcgcagggcc gatatccggt
    12661 cccacgccgt ctcctggagg gaggcataca gacggcgggc gcgtagcgcc tgcccgagat
    12721 cgcccgctcg ttccaactcg gtggccagcc agctgagctc ggaggtgtcc aggcggctcg
    12781 gatcgtcggt ccgccggagc ctgctctggt ccaggaagat ctcgtccagc gcgcggatca
    12841 gcgggactcg ggccagttcc gtcatgccct ggtccagggc gagcccggtc cacagggaca
    12901 ggggctcgtc gtccggatcg gagccgaaca tccactcgtc cagctcctcg gcccagcgca
    12961 gcagttcggc ggcgtccgcg cccggctcgg gcatctcgct gagcccgcag tgcgtgtcga
    13021 agtcggtctc acggacctcg tgcagcaggg gcaggtcggc gacgtccccg taccgcccca
    13081 cgaggacggc ggcgagccgg agttcgtccg tcatcgacga ctccgcctcc cggcgcagca
    13141 actgccgcag ccagtctccg tcgccctcgg cacggtcgaa ctgcgcggcc cgcagggcga
    13201 gtcggcgccg taccgggtca tcggcgaccg cgtcccggtc ggcgcggtcg cccgtgcgca
    13261 gcagggccag atccgcgcgg ccctgtgcca gcaccggctc ccacaggggc gggcgcggat
    13321 gcgggtccag caggtcgtag gcgccgccct cctcgtcgtt gagcagcacg aagtcgggtt
    13381 ccgtgcgcag aagcgcggag tgcagcaggg ccaccagctc caccggggag cggtcgggga
    13441 agcccagcgc ggcgcgcagt tcggcgcggg ccgcctcgaa gcggtcgtcc tcgcggagcg
    13501 cctgcgcggc ccgcgcgagg atcacctccg cgccgtcccc aggcgacagg tccacgaagt
    13561 cgaaccagca cggcaggccc agcaccacct ggagcgcctc gtcggcagtg gagccgatga
    13621 tcccggcccg gccctcggag tcggcgtaga gcatcgggcc gcccgcgcac acgaaatacg
    13681 tgccgcccgc cccgtctccc gccacggcct cgatcggtgc gcccgaggcc aggcggaccg
    13741 gctcgccgtg ctcggcccgg ctcaggtcga agtcgaacgg gaacgcggcc aggtcggcca
    13801 ggcgtgggtt ctggcgcagg gtgcgcagcg cgtcgtcggt catgtcacag aacgtaacag
    13861 cccccactga cagtgaccct gggccgtcca ctgtcacccc cgccggcctg ctggtccggc
    13921 cctcggcctc acctccggcc gcgcgcccgt tccaccgccg ccttggccca cgccgtgacc
    13981 atcgggtgcg ggcgggagcc gtcgccggac agttccggct ggaagaggga ggccaggaag
    14041 aaggggtggt ccggcagttc ggcgatgcgg acgtggccgt cctcgtcgtg ccccgagaag
    14101 cgcagtccgt gcgcggtcag ggtgtcgagg tggcgggtgg cgccgtaggc gcagaagtag
    14161 cgctcgacgg tccgttccgc gccgatcacc gaccgcgcga gcgagtccgg ctccacgagc
    14221 accgcgccct cgtgacccac cagcgagcag gccagcggct cgatcagcgg gtcggcggcg
    14281 tccgggtcgt tctccgcgtg ggcggcgccg gtcagcccgc agacctcgcg ggcgtactcc
    14341 agcagcgtgt gctggaagcc gccgcacgtc ccgaggaagg ggatgccccc ctcacgtgcg
    14401 gcgcggatcg cccggagcac cccggcctcg ctgcggtacg ggctgcccgg taccacccac
    14461 accgcgtcga agccgtccac ggcaccgggc ccggcggcgg cctgccagga ggggacccag
    14521 tacgcgtcga ggagcagccg ctcccggtcg gcgagcgcgt cgaggaggag aggcagccgg
    14581 gtgtgggaca cgacattggg ggagcggtcg ccgaccaggg cgacccgcgc gaggggctcg
    14641 gtcatggcgt tcatcctggg cgccgtcgcg agttcacgtc caacgatgat ccctgcactt
    14701 ccgataagca gagctgatgt catcctggtc gccatggacc cgcacctgct gcgcacctac
    14761 gtcaccgtcg cccgcctcgc ctccttctcc gaggccgccc gcgcactcgg ctacacccag
    14821 tcggcggtgt cccagcacat cgcggccctc gaacaggacc tcggcgcccc gctcctcacc
    14881 cgccgcccgg tcgcccccac ggaggcgggc gcccgcctcc tggagcacgc ggaacccctg
    14941 ctgctgcgcc tggacgcggc ccgcgcggat gtcgtacggc tggccgcggc gcccccgcgc
    15001 gggctgacgc tcgccgccgc gcccaccgcc ctcggcccgg cggtcctggc cgcgctcccg
    15061 gcggccgggg tgaccctgaa ggtgctgccc cgggacggcg tcccggcggc cgtcgccacc
    15121 ggcaccgccg acctgggcct cgtcgacggc ctcgccgccc ccagcgaccc gctgcggatg
    15181 ccggacgtgg caccgctgac cacacgcggc gcgggcgagg aaccggtgtg cgtcctgctg
    15241 cccgaggccc atccactggc ccggcgtccc gggctgagcc tgcacgacct cgtcgacgcc
    15301 cgctggctcg acgcccccgg ggcgggcccg ccgctcgacc ggctccgcgc ggcggtcggc
    15361 ggccacggct tccgcccggc cctgcgctac gagggcgccg acgtacgcgc cctcaccgct
    15421 ctcgccgccg cgggccacgg cctgaccctg ctgccccggt gggccgcgac cggggtgccc
    15481 ggcgcggtcg ccgtcccggt caccgagccc cggatcgtcc accgcacgga gctggtgcac
    15541 gcgggcgcac tccggggcgc ggcacaggag ctggcgttcg cactgacgtc cggggagggt
    15601 ccggacttcc gctcctgagc gggcgtcagt ctcactcgtt cgtggcacgt tgtgcgccgg
    15661 agcgccgggt agtcctcagc cggagccgga ccgcagccct cagcccgagg tcgaccgcgg
    15721 tcctccgtcc ggaggcgatc catggaacac accgcgttgc gccccaagcc gatgcccggc
    15781 cgggagcccg gcgacggccc gcgcacgaca cccaccccgc gaccacgcgc cgcgcgccgg
    15841 cgcggacgcc ggttcaccac cgccctgttc gcgctgttcg tcggcgcggt cctggtgctg
    15901 tccggcgtcg gactcggcac cgtcggcgcc accgtgatcg gtatgagcaa actcgccgag
    15961 gctcagcagg cacagcaggc gagcacccgc gcccacgccg ccccctccgc ctcgctcgga
    16021 ccccggcccg ccccggccgc gaccgccgcc cgcgcgacgc tgggcgtgga ggcggtggac
    16081 gccgagaagg cgggcgcccg cctcgtcggc gtccacgtcc cgggccccgg ctacgcggcg
    16141 ggcctggtgc gcggcgacat cctcctcgcc ttcggcagga cccgcgtcga cagcgcgacc
    16201 gacctcgccc gcgcggtggc gaaggcccgc cccggcaggg aggtcacctt gacggtgcgc
    16261 cacgccagtg gcggctacca gcagctcgtc gtggtgccgg gcgtggtgac ctgacgggcc
    16321 ggacgggccc gacaaccccg gggaaacaac gtcaaccggc tcgcgccgcc ctctccgtgc
    16381 gggcaggatg ctgcccgtgg tcaccttcac ccgtccaggg aggcacggat gagcaccccg
    16441 acgcccgccc ccttcaccgc cgaggactac cgggcccgta tggagcgcgc cgcgcgggcc
    16501 gccggtgatg ccgggctcgc cggtctgctc gtcgcacccg ggcccgacct ggtgtggctc
    16561 accggatacg cgcccccggt caccgaacgg ctcaccctgc tcgtcctcgt ccccggccgc
    16621 gaccccgagc tggtggtgcc cgccctggag gccccggacg ccgccaaggc gccctgcggg
    16681 cccgcgctgg ccctgcggga ctggaccgac ggcaaggacc cctacgccgt cgccgccgcc
    16741 ctgctggacc ccggcggccg gttcgggatc agcgacaacg cctgggccat gcatctgctc
    16801 ggcctcaccc acaccttgcc cggctcctcc tacgcctccc tcaccgaggc gctgccgatg
    16861 ctccgcgcgg tgaaggacgc cgcggaactg gagcgcctcg cggccgcggg cgcggcggcg
    16921 gacgccacgt acgaggagat ccggcggctg cccttcgccg ggcgcaggga gtccgaggtc
    16981 gccgccgacc tggcccggct gctgcgcgag cacgggcact cccaggtcga cttcaccatc
    17041 gtcgcctccg gcccgaacgg cgccgacccg caccacgagg cggacgagcg ggtcatcgag
    17101 cgcggcgaca cggtcgtcct cgacttcggc ggcctgctct gcggctacgg ctccgacacc
    17161 tcccgcaccg tccacgtcgg cgagcccacc gaggaggagc gccgggtcca cgacatcgtg
    17221 cgcgaggccc aggaggcggg cttccgcgcg gtacggcccg gcgtggcctg ccaggagatc
    17281 gaccgggccg cccgcgcggt catcgaggac gccgggtacg gcgagtactt cattcaccgc
    17341 accgggcacg gcatcggcgt caccacgcac gagccgccgt acatggtcga gggcgaggaa
    17401 cagcccctgg tgcccggcat gtgtttctcc gtggagcccg gcatctatct gcccggccgc
    17461 ttcggggtcc gtatcgagga catcgtcacg gtcaccgagg acggggggag gcgcctgaac
    17521 aacaccaccc gggagatggc catagtggac tgaggaggac aattgcagcg gttccggccc
    17581 ctcctccggg cgccggcttc agtgacaacg gcttcagcaa caccggctct agtgacaacg
    17641 gcacgaccat gacccaggca ccgacaccca ccgcggacac ggtccgcaga ctggtccgtt
    17701 ccctgctcaa ggacggcgcg gacgacaccg cgggacccga ggtccggccc gtcgcgcccg
    17761 gcgacgaggc cgtcacctgg tgggtcggcg cccgccatgt gctgcgcctc gcccccgacc
    17821 gggacggcac cgtccgccag cgccgcgaga tgcgcctgcg cgacctggtc cggccgcacc
    17881 tgccggtcgc ggtgcccacc agcgtcgcgc acggcgagtg ggcgcccggt ctcgcctaca
    17941 ccctggacac caagctgccc ggcggctcgg ccgaggtgca cgacgtgtcc gccgtcggag
    18001 aggccgacct cgcgggactg ctcacggggc tgcgcgaggt gtccgtacgg caggccgagg
    18061 cgatcggcgt gccgcgcacc ggcccgcgct ccctggaggc gctgcgccgg gccgccgaac
    18121 gcgccgccgc ccgcctcgcc gaggccgacg agttcgaccc ggcccggctg caccagctca
    18181 ccccgccggc cgcggtgcag ctcgccgccc agcccggcac cgccgtcctc gtccaccacg
    18241 ggctgaccgg cgagcacctc gtggtgagcg ccgacggacg ggtgcgcggg gtcctcggct
    18301 ggaccgacgc ggtggtcggc gaccccgccg aggacatcgc cggtctcgcc cgcgcggtcg
    18361 gctccccggc cgccgtgcgc gccgccaccc tggcgggcta cggcgcccgc ccgtgtctgc
    18421 gcggcctgtg gctggcccgc tgcgacaccg tgatccatct cgccgaggcc ctcgacaggc
    18481 ccggccgcac ccccctgccg gagctgcgcc ggcggctcga actggcctgg gaggcgatcc
    18541 tgctggagcg ggtcacggaa ctccgcgagg acgacgaccc ggacgagggc ccctgaggct
    18601 catcgggctc ttccttcgtg gatacccccg gcttcagccg ggggaggaaa cgaagctcct
    18661 gcggagcagg gcagggaaag ccggttcgcc gccagggcgg accggcgtcc tccgaccacc
    18721 ggccaacagc cgcctctcac acggaagctg atacaatgtg aggaatgacg cagcaggtca
    18781 agcgggcttt caagtaccgc atttacccaa cggacgagca ggcagcggag ctgtcgcgca
    18841 cgttcggctg cgtccgcctc gtctacaaca aggcgctgga ggagcgcacg cgcgcctggt
    18901 acggcgagca gcgccggatc tcctacgtgc agtcctcggc cgcgctgacg gagtggaaga
    18961 agaccgaaga tctcgccttc ctgacggagg tgtcctcggt cccgcttcag caggcgctgc
    19021 gccatcttca gacggcgttc gggaacttct tcgccaagcg ggcgaagtac ccccggttca
    19081 agtcgcggaa gaagtcccgc gcgtcggccg agtacacccg ctccgcgttc aagtggcgcg
    19141 acggggagct gaccctggcg aagatgacgg agccgctgga catccgctgg tcgcgtccgc
    19201 tcccggaggg tgcggtgccg acgacggtga ccgtgtcccg cgacgcggcc ggccgctggt
    19261 tcgtctccct gctctgcgag gacaccatta cccccgcgcc tgccaccacg gcggcggtcg
    19321 gcatcgatgc cgggatcacc tccctggtga cgctgtccac cggagagaag atcgccaacc
    19381 cccggcacga gcggcgcgac cgtgcccgcc ttgcccgcgc gcagcgggag ctgtcgcgga
    19441 aggcgaaggg ctcggcgaac caggagaagg cccggcgccg tgtcgcgaag gtccacgccc
    19501 ggatcgccga ccggcgccgg gacttcctcc acaagctgtc gactcggctc gtccgtgaga
    19561 accaaacggt cgtgatcgag gacctcaccg tccgcaacct gctgaagaac ggcaagctcg
    19621 cgcgcgccat ctcggacgcg gcctggacgg acctgcgcat gatgctggag tacaagtgcg
    19681 cctggtacgg gcgcgaactc gtcgtgaccg accgctggtt cccgtccagc aagctgtgcg
    19741 gggcctgcgg cacggtcgcg gcgaggatgc cgctgaacgt ccgcgagtgg acgtgcgact
    19801 gcggcgtggt gcatgaccgc gatgtgaacg cggcacgcaa catcctggcc gccgggctgg
    19861 cggcgtctgc ctgtggagac ggtgtaagac ctcaccggga gtcctcccgg acggggcggt
    19921 cgtcggtgaa gcaggaatcc cagcgggcga ccgctggaat cccccgcctt taggccgggg
    19981 aggaagtcaa tcctggagca gcaccacacc cgactccccg ggcaggtgca gcacgccgtc
    20041 ccgccccggc acctccaccg gctcccacgc ggccagcacg cgcgcgtgcc ggggccccag
    20101 cgggatctgc gcggggtcct tgccgaggtt gacggccacc cggacgtcac cgcgccggaa
    20161 cgccagccag cggtgccgct cgtcgaaggc gaccttggtg tcggcgaggt cggggtcggt
    20221 caggtcgggc tgttcgtggc gcagggcgat caggcgccgg taccagtcga gcacgcgcgc
    20281 gtggggctcg cgttccggct ccgaccagtc caggcaggag cggtcccggg tcgccgggtc
    20341 ctgcgggtcg ggcacgtcct cctcggccca gccgtgcgcg gcgaactccc ggcgcctgcc
    20401 ccgccgtacc gcctccgcca gctcggggtc ggtgtggtcg gtgaagaact gccagggcgt
    20461 gcccgccgcc cactcctcgc ccatgaacag catcggcgtg aagggcgccg tcaggaccag
    20521 cgtcgccgcg caggccagca gaccggggga gagggcggcg gagagccggt cgccctgggc
    20581 gcggttgccg acctggtcat gggtctggct gtagcccagc agccggtgcc cggccacccg
    20641 ggagcggtcc agcggacgcc cgtggtgcct gccccggaag ctggagtacg tgccgtcgtg
    20701 gaagtagccg ccggtgagcg tcttggcgac ggcggcgagc ggggcgcgcg cgaagtcggc
    20761 gtagtagccc tgggactcgc cggtcagcgc ggtgtgcagg gcgtggtgga agtcgtcgtt
    20821 ccactgggcc tggagcccga gtccgccctc cgcgcgcggg gtgatgatcc gcgggtcgtt
    20881 caggtccgac tcggcgatca ggaacagcgg gcggcccgtt tcggccgcga gggtgtccac
    20941 cgcggcggac agctcctcca ggaagtggca cgcgcgcgtg tcgcgcagcg cgtgcaccgc
    21001 gtccagccgg agcccgtcga tccggtagtc ccgcagccag gccagcgcgc tgccggcgag
    21061 gtaggcgcgc acctcgtcgg agccgggcgc gtccaggttg acggcggcgc cccacggcgt
    21121 gtggtgggtc tcggtgaagt acggcccgaa ggcgggcagg tagttgccgg acgggccgag
    21181 gtggttgtgc accacgtcca gcacgacccc gagcccgagt tcgtgcgccc ggtcgacgaa
    21241 gcgcttcagc gccgcgggcc cgccgtacgg ctcgtgcacc gcccacagcg agaccccctc
    21301 gtacccccac ccgtgccgtc cgggaaaggg gcacaccggc atcaactcga cgtgcgtgac
    21361 acccagttcg accaggtgcc cgagccgctc ggccgccgcg tccagggttc cctcgggggt
    21421 gtacgtgccc acgtgcagct cgtacaggac cgcccccggc agcgggcggc ccgcccagtc
    21481 ggcgcgccag gtgtacgcgc cgtggtccac gaccgcgctg agcccgtcgg ggccgtccgg
    21541 ctggcggcgc gagcgcgggt cgggcaggac gggtccgtcg tccagcgcga acccgtaccg
    21601 ggtgccgtcc tcggcctccg cctccccctg ccaccagccc tcccgctccg gatcgcgctc
    21661 caacgcgcgc gtggcgtccc cgtgatggag cgtgacacgg tcggcctgcg gtgcccacac
    21721 ctcgaactgc acggacggtt ccccttcgtc tgctcaccgt gatgtagccc gtccatggtg
    21781 cttcaaacga gatcaatccg cgtcggcatc agcccttttg ccgcaggtgt cgccggatgt
    21841 acgcacctgg ctacggtttc ctcgatttct ggacaccccg cccccgctga ccgacaatca
    21901 ccagcgtgac gtcgtccttc gagttcaaca cgtaccccgc gcggctctcc gacgcggagc
    21961 gcgaccatgc gctgaaggtg ctgcgggacg gcgtcgccat gggccggctc tcgcacgaca
    22021 cgttcatccg gcgcatggaa ctggccctcg ccgcccgccg ctccgacgag ctggccgccc
    22081 tcaccgccga cctcccccag gagagccggc tgtcccggct ggtgttcggc accgtcgagg
    22141 ccgtctccgg gttcggcgta cggctgcgca gcgcctggcg ggccgagcgg ctgccgaagc
    22201 tgctgctgcc gcaccccggc agtgaccgtg cgctgcggat cggccgggac cccgccaacg
    22261 gactgcggct gacccacgag acggtctccc gggtgcacgc cgagctgtc
//
