LOCUS       NZ_CP104794            23798 bp    DNA     linear   CON 09-JUL-2024
DEFINITION  Streptomyces sp. FZ201 chromosome, complete genome.
ACCESSION   NZ_CP104794
VERSION     NZ_CP104794.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. FZ201
  ORGANISM  Streptomyces sp. FZ201
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8604396)
  AUTHORS   Zhang,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2022) College of Life Science and Technology,
            Jinan University, Guangzhou, Guangzhou, Guangdong 510632, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2021
            Assembly Method                   :: unicycler v. 3.14.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 235.1x
            Sequencing Technology             :: Illumina NovaSeq6000; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025402955.1-RS_2024_07_09
            Annotation Date                   :: 07/09/2024 06:54:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,562
            CDSs (total)                      :: 7,471
            Genes (coding)                    :: 7,336
            CDSs (with protein)               :: 7,336
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 55 of 135
            Pseudo Genes (incomplete)         :: 92 of 135
            Pseudo Genes (internal stop)      :: 7 of 135
            Pseudo Genes (multiple problems)  :: 18 of 135
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:45:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4566423
            Orig. end                         :: 4590221
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP104794.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zhang Fei, College of Life
            Science and Technology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23798
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="15"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23798
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23798
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13798](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13798
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(129..143)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    275..288
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.9"
                     /tool="antismash"
     gene            704..1933
                     /locus_tag="N6J21_RS20455"
     CDS             704..1933
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013739.4"
                     /locus_tag="N6J21_RS20455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_261719008.1"
                     /transl_table=11
                     /translation="MSEVVVVGAGVAGLACAVRLAEAGVDAQVLEARSRTGGRVRSFRP
                     ADGGPALELGAQIVHGDRNPAHTVLGPLPALPRPTAAYVVSGRTARPMALLARGGCPPW
                     LAEARLAAYREGSVSVGSWLTTLGAAPAEVAVAREWFRQTWAADPGRIDAAAAGLAMRQ
                     DPGGRGEFTAPGGLDVLTARLAERVRVRTGVPVRRIAVEPDGSGVRLATEDGETTASQV
                     VVTVPPAVVDRGLLTIDGLDEDRRAAARTLAPGDAYCAVVTLSGPAPQDISVFDADGAG
                     GFLSCRRGRPEVTLVAKDTAAACVRAAAGSAGQLAALLAVALPWTAALDIVAVETADWS
                     AEPFSGGGFCAPGPDSTAAAERWARPLGGRLFFAGEAAVTGRALPWLQGAYADGRRAAE
                     EVLKARKQGQ"
     gene            1930..2856
                     /locus_tag="N6J21_RS20460"
     CDS             1930..2856
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012575.4"
                     /locus_tag="N6J21_RS20460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="WP_176711899.1"
                     /transl_table=11
                     /translation="MNVHSGWYLAAFTSELEGDVAPLDIGTRRLVAVRTGGALRVYDAD
                     CPHRGAHLGRGGRVEGGCLVCPFHGRRIGLGRPEREGPRPWVREHEVIVCGEAVFVRLT
                     DGPDDDRGMRATLKELAGTHPLVRAVARPVAAAADLIVENAFDTEHFTALHKVYRVRGM
                     RHRDGAHGELVMDGEFPMPASPWRGRPGAPAAEPYVPRFHARAFSPAVVVTEFGPADEV
                     HIIVTGAVPDASGGCVARVAIGVREGQQAALPALIAGSERALAEDIDVWEHLNPAVVPR
                     YDEADAAVVAYRAFCEGFTDLGTPGAS"
     gene            2853..3815
                     /locus_tag="N6J21_RS20465"
     CDS             2853..3815
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (42-276). E-value:
                     6.3e-18. Score: 57.2. Matches aSDomain:
                     nrpspksdomains_N6J21_RS20465_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="N6J21_RS20465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_261719009.1"
                     /sec_met_domain="PF00561 (E-value: 5.7e-11, bitscore: 41.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1e-14, bitscore:
                     54.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVRRCATDPDCAACTAAAGPLPGETGATRDGLRVRTWGGDGPTV
                     LWVHGYTMDATLWRPLWRLLPGLRHVGVDLPGHGGSAPLDPGTTLPALAARVLELARAE
                     GARRWVGLSFGSTVTLQMALDAPGAVDRLALGAPTPAGGPPDPAARKRYIELLMLRRMR
                     GPAAADQLADLWMASPPDIFRGTEAHPGLRSRIRAVVARHSWAELDNGAMAALSAHTHP
                     PEDLSRITADTLALTGADDMPVFHSNAALLAVELPRCRTEVVPDAGHLPFLERPLAVAP
                     VLAAHLAGGPVSTEHVRDLRATTTNAPRIKEFMGEEPPV"
     aSDomain        2979..3680
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_N6J21_RS20465_Abhydrolase_1.1"
                     /evalue="6.30E-18"
                     /label="N6J21_RS20465_Abhydrolase_1.1"
                     /locus_tag="N6J21_RS20465"
                     /protein_end="276"
                     /protein_start="42"
                     /score="57.2"
                     /tool="antismash"
                     /translation="PTVLWVHGYTMDATLWRPLWRLLPGLRHVGVDLPGHGGSAPLDPG
                     TTLPALAARVLELARAEGARRWVGLSFGSTVTLQMALDAPGAVDRLALGAPTPAGGPPD
                     PAARKRYIELLMLRRMRGPAAADQLADLWMASPPDIFRGTEAHPGLRSRIRAVVARHSW
                     AELDNGAMAALSAHTHPPEDLSRITADTLALTGADDMPVFHSNAALLAVELPRCRTEVV
                     PDAGHLPFLERP"
     gene            3900..4916
                     /locus_tag="N6J21_RS20470"
     CDS             3900..4916
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N6J21_RS20470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_093722018.1"
                     /transl_table=11
                     /translation="MEGPELSYFFGPHLLGLRKTPEKEKASLTVHLGQRSGSGGRGVRV
                     FGPDGRLLRRWSFHGMGGIPPLLPPFAAMNGQYAVVQAAVLAEGDRVVALIGGVGSPRN
                     SVALALGGRGWRMVSSQYLVVDRATGHTLPYQLPMELRGVDLDAVRAAGLADGPDAVDA
                     TPGGPTALPGLGAAEDGGAYAWSGDLRRVQSPLTGPYLQVRPERLLATVDRGARLGPAH
                     LVRLCCTGTDRCELEEWDVTPSVWPPEAADGLPAASRLRLLLPGTRSADEAADLLHERL
                     TSLPAAKGTVLCPAEPRTPREHPAGSTTWGSTRPAPRSSTQPSSVGSSDPRAAVATT"
     gene            4826..5434
                     /locus_tag="N6J21_RS20475"
     CDS             4826..5434
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N6J21_RS20475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="VOC family protein"
                     /protein_id="WP_250747826.1"
                     /transl_table=11
                     /translation="MGVDPTGAKEFYTALLGWEFRPEGGRGYHLILLGGEIVGGLGPSP
                     MGPRFGSSWNVYLAAKDLDAAGERAERHGARLLARGVPAGGDGRLSLAVDPQGAPFGLW
                     QGMREEGVVLVDEPGALAGAVLHSPEPEDSAAFYGAVCGSDARIEKGSPARWMPLLGAD
                     APDAFEERARAAGATVLAPGVLADPWGAVFGVADVAVPR"
     misc_feature    5609..5627
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(5659..5673)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.65"
                     /tool="antismash"
     gene            5668..7065
                     /locus_tag="N6J21_RS20480"
     CDS             5668..7065
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (halogenases)
                     flavin-dependent cycline orsellinic halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119: halogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998212.1"
                     /locus_tag="N6J21_RS20480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_261719010.1"
                     /sec_met_domain="Trp_halogenase (E-value: 2.5e-27,
                     bitscore: 94.6, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPEIVVIGGGPAGSISAALLARNGARVRLLERAHFPRYHIGESV
                     ATSCRAIIELAGALEKVDARGYQVKEGLLLRWGAERDWVVDWPEIFGTGAQTSWQVDRA
                     DFDHVLLRHAASQGAEVTEGAQVKRVLFEDGRAVGVEWTHEGVTSTTRADHVIDASGRA
                     GVLSARHFRDRRQHDVFRNVAVWAYYKGGSLLPRTPRGGIDVISSPEGWYWVIPLADGM
                     FSVGFVTHQDNFLRRRQDCPDVERLFLDFVQESDTVRELMADGEFQHDVRVEQDFSYAA
                     DSFCGPGYFLTGDSACFLDPLLSTGVHLAMYSGMLSAASILALHDGDVAEPEALSFYET
                     LYRNAYARMFSMVAGFYEQYRGKATYFWLAQRLARGRYPELVRRPEPVPMRSAPDSEAF
                     AALTAGALDLDDARRAGGADPLAAEVLAAQVAPRATARDRFDAATGLYLRTEPRLGIGR
                     VTETART"
     gene            complement(7210..9744)
                     /locus_tag="N6J21_RS20485"
     CDS             complement(7210..9744)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="N6J21_RS20485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_261719011.1"
                     /transl_table=11
                     /translation="MHAVNGDLYHREREISLLQEVIAGLALGRPAVVTVHGPRGMGKSA
                     LLNVVPRLLPEGALVLRARCHPSESGFPYSMVRQLFDPVLGAAGRAETFIPAEGHGSSG
                     EAAGPTHEALLHLLSTTRSLAADRPVAVLVDDLQYADEPSLRWFSYLARRLDDLPVLLV
                     ATLPDSAAARLTDELGPLPYLYRLWPEPLCSTCTTELVDRAFDSPVDQGLAALCDALAH
                     GNPMVLHDLVNRLRREHVPPGAPDPQQVLPIGAQALSETVLAWLDEDDPAAGELLTQLA
                     VLGPDTDPAMCGALSQHGEVQVLQARDALVRAGLLEAGPPARFPHAAVRPAVLARVPAE
                     DRLHLHGRAATVLARLGAPARQTAEHLVKAGCEWGLDVLRDAGAQAAAAGDHASAARYL
                     RRALALLDGPPPGDASAPERPGETPHAETFHELTVRLASVELHRDLDACARQTVAAADS
                     APGPVGRAEVLARLASPALVASLEGAQPFVRACGELAALAAPPREPLLRLTAQALLTGH
                     RAGVRAAARLAARGPLDPAARSFSGALAAAAAATGRTGTAQRLAARVEVAQGAAQEAVT
                     AGWPAGPIGAALALIWTGAPAAARDLATRVLTTARAADDGATVLLARLVRAEAHHREGR
                     FSTAYADAEAGLALARRLNAAALTSAALSCAARALVGLDRADDAAEVLREDRSAGDLHP
                     FVRALSLQARGEVAAARGDHTAALGLFLDCGHRLALRGITNPACLPWRTQAARAYRALG
                     EEAAAATILNGGPRTPAVTPHPASAPHDPERPTLTPAEQRVVELVLRGHSSLEVSERLF
                     LSKRTVDTHLGRVYRKLGIHSRHELAAALSVP"
     gene            10001..12253
                     /locus_tag="N6J21_RS20490"
     CDS             10001..12253
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03604.1"
                     /locus_tag="N6J21_RS20490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_250747822.1"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 5.5e-18, bitscore:
                     63.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 9.9e-15,
                     bitscore: 53.1, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 7.7e-14,
                     bitscore: 50.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 2.6e-85, bitscore: 285.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 7.1e-74, bitscore:
                     247.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKPRLKAHFHVEVVEGERVFLYAEGQDYLVPGKAAAAVVPYLDG
                     RRTVMEIVQALSGTVAIPAVLGALTRFEAAGHLAEGRPELDESVLAYWDALGIDPATTL
                     GTAPVTVSAAPGVDPEPVVTALRGLGLTVATAPLDSVPEAGLSVVLVDDYLDPALAARN
                     DRQLAAGLPWLLARPAGVAPWIGPFLKPEHTACWRCLSQRLTGNRQLERYLAGRRGESV
                     PRHPARAGIAAGPLAAAGLLAAEAARIAATGEPGALCGQMITLDLATLRTETHPLVRQP
                     QCPSCGDPALVTGRSPKVVLSSQEARHTSDGGYRVNRPEDTLARLERHISPYFGAITKL
                     VSHTPESNTLTYSYSAGHNFAMVNDSLDLLRRNLRGQSGGKGRSEIQAKVSAVCEAIER
                     YVGVWRGDEPVVRAAYRDLDAGIAVHPSSLLHFSEGQFAGRAEWNKDPANRLHKVPDPF
                     PEDTPVDWARGWSLTHDAERLVPAAYSWYGHPDLDDNFFCIADSNGSAAGNTLEEAVLQ
                     GLCELTERDAVALWWYNRLRRPAFDMDSLDDPYVTQLRAHYEAMDRDLWMLDISFDLGM
                     PVYVAASRRRHSVEDIMVGFGAHPDPRVAAFRALTELNQFLPMIEQRDAQGNTSYLVDD
                     LETLTWLKEATVEREPWLLPDPELPAVRVGPRAGFDLSERIREQVERIREAGSEVIVLD
                     QTRPDLELHVVKVIAPGLRHFWRRLGPGRLYDVPVRLGLLERPTAEADLNHWNVFF"
     aSDomain        10007..10282
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_N6J21_RS20490_NHLP_CD_RRE.1"
                     /evalue="2.10E-20"
                     /identifier="RREFam015.1"
                     /label="N6J21_RS20490"
                     /locus_tag="N6J21_RS20490"
                     /protein_end="94"
                     /protein_start="2"
                     /score="63.5"
                     /tool="antismash"
                     /translation="KPRLKAHFHVEVVEGERVFLYAEGQDYLVPGKAAAAVVPYLDGRR
                     TVMEIVQALSGTVAIPAVLGALTRFEAAGHLAEGRPELDESVLAYWD"
     aSDomain        10013..10234
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_N6J21_RS20490_Cyanobactin_D_RRE.1"
                     /evalue="3.70E-17"
                     /identifier="RREFam007.1"
                     /label="N6J21_RS20490"
                     /locus_tag="N6J21_RS20490"
                     /protein_end="78"
                     /protein_start="4"
                     /score="53.1"
                     /tool="antismash"
                     /translation="RLKAHFHVEVVEGERVFLYAEGQDYLVPGKAAAAVVPYLDGRRTV
                     MEIVQALSGTVAIPAVLGALTRFEAAGHL"
     aSDomain        10013..10291
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_N6J21_RS20490_Goadsporin_CD_RRE.1"
                     /evalue="2.90E-16"
                     /identifier="RREFam013.1"
                     /label="N6J21_RS20490"
                     /locus_tag="N6J21_RS20490"
                     /protein_end="97"
                     /protein_start="4"
                     /score="50.4"
                     /tool="antismash"
                     /translation="RLKAHFHVEVVEGERVFLYAEGQDYLVPGKAAAAVVPYLDGRRTV
                     MEIVQALSGTVAIPAVLGALTRFEAAGHLAEGRPELDESVLAYWDALG"
     misc_feature    complement(10017..10031)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.28"
                     /tool="antismash"
     gene            12347..13798
                     /locus_tag="N6J21_RS20495"
     CDS             12347..13798
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.4"
                     /locus_tag="N6J21_RS20495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_261719012.1"
                     /sec_met_domain="PF00881 (E-value: 1.4e-15, bitscore: 56.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITTSPLTTARDGADSTPAPCTEAIRLTRGATFDGERITAPFGT
                     LRLKELPSGARAALTALAGEDLDEGRITALVVAGDGEAGLLRWHMLRTRLDNTGLLEHS
                     VTGADGTTLARLVTVGRGRTTLRPVPRDAVRLSRHALLLPADGTLSLRAPGSPLAVELG
                     PAAAPFLARLTDWTDAARIPAPLLRLIATAGALNPGTPEDDPEREQRGGVQWHPLDLAF
                     HTRTRVPASVAGYGGTYPFADRFPPEPVAAPAGDGPRVPLPVPDLDEIAARDPSLTEVI
                     ESRTSTRAHDPGSPVTVDQLAELLYRTVRIRATFTGGDGQELADRPLPSGGSVHELEVY
                     PLVTNCAGLAPGLYRYAPDRHELELVREPGPATEPLVREARAATMADDDPQVVLLVAAR
                     FGRVMWKYETVAYPLILKHVGVLYQTVYLVATAMGLGVCGLGGGDTSAFAAATGCDPLL
                     EGTVGELVLGTPRLTAPGGPADREE"
     gene            13803..14615
                     /locus_tag="N6J21_RS20500"
     CDS             13803..14615
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024829.4"
                     /locus_tag="N6J21_RS20500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_093723150.1"
                     /transl_table=11
                     /translation="MQFRYQALQRKREPDELDAPVLLAAPRGWIAVFVVLITMAGACVW
                     AVFARLEVTVDAPGILTHPGGTSQVQSPYTGLARELLVHPDDEVKAGDPLARLTDDAGR
                     VRTVTSPFAGKVISAALTSGQFVRAGSTVATVERTDLPDDRLVALVFVPADQAAGLRPG
                     RPVDLSVSTAPPSVYGLLRGEVTSVSPYPLTREGLAAVAGGDLAAEAFHQDQAPRLVTV
                     DLIPEPGSPSGYAWSTAQAPPVRLGSQTSVSASIGLRSQSPFALLLGR"
     gene            14629..16977
                     /locus_tag="N6J21_RS20505"
     CDS             14629..16977
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640763.1"
                     /locus_tag="N6J21_RS20505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NHLP family bacteriocin export ABC transporter
                     peptidase/permease/ATPase subunit"
                     /protein_id="WP_261719013.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.5e-33, bitscore:
                     112.7, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDTKSTTATRTTGPGGPPGGPGRDAPVSPRRARRAERRGRRGAA
                     RERRWARRRAHRVPTVLQMESVECGAASLAMILAHHGRHVPLEELRSLCGVSRDGAKAS
                     SVLAAARSFGMVARGFQAEPDLLREKLRTGPVIIFWAFQHFMVVEGISTRFGRTLVAVN
                     DPSTGPRLMEWSEFDSGFTGIVLTFEPGPDFRSGGRRTSTAAALLDRRLPSGRALPLVL
                     LASLLLVVPGIVGAAYSRVFVDQVIGADSSTAVLPLAVAMAVTALMVFVLTSVQQHYLL
                     RMEIRTGLVSSARFFRHLLRLPIEFFLQRRPAEVAKRVASNDTVAMILSRDVAATTINL
                     TLVVFYGALMIRYDVLLGAIGLATAGLNVLMLQLVARSRKDAVAALRADRGNLIGTTFA
                     TLSTIESVKASGSEPEAFTRWAGFLAKVTSAQQRLGQTTAVLTVLPPLLAVVNIGVLLL
                     VGGLRVADGTLSVGILVTFQTLLAALSRPVTQLTNLGSRLQDMNADLKRIHDVEKYPQA
                     GCFEPGRDELDPEAPEGRLNGELVLRDITFGYGPLAAPVISGLCLTIAPGSRTAVVGGS
                     GSGKSTVGRLVTGLYEPRSGQVLLGGRPREEIPRTVLAASMAYVDQDVALFSGTVRENL
                     TLWDDTVPDEVVLAALQDAAVFDEVLSRPGGLNAQVWEHGANFSGGQRQRLELARALAA
                     RPTLLVLDEATSALDPATERTVMDNLRRRGCACLIIAHRLSTVRDADEIIVLDKGTVAE
                     RGTHDELLAARGLYAALFESSRAEESDTL"
     gene            16974..20177
                     /locus_tag="N6J21_RS20510"
     CDS             16974..20177
                     /GO_function="GO:0015440 - ABC-type peptide transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR03797.1"
                     /locus_tag="N6J21_RS20510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NHLP bacteriocin export ABC transporter
                     permease/ATPase subunit"
                     /protein_id="WP_250752546.1"
                     /transl_table=11
                     /translation="MTNPDNAPAATAGTGASDTPTTPASGVPGGIAGGGEGGAGPDTPS
                     AGAAADVSVQTSPDHPTDPAPEPPGTPTRTVCLDDPGTLLYVAEGAADLFAVERAVTDG
                     RAGAAGPDDGDGAAGRRHFLCRADAGMLLVCGTDRDTRHTVVARPVLDAQLHRLPLEVL
                     DDVRAGRTALPRADGERPAELDHARVLDGLTAGLTALAEALAGTLPPRKFTSLSTRGST
                     ELEARDVTRSVDGVRFVRVESGLLDQGDRAGAEQRAPDLPEAPEPVGPGDEVVLTERDW
                     LRAREPARLTSASLLDVYRQGRLTAALARYAVRLRAAVDHRVAVVRAEERAELAARRAQ
                     DATVPAAAVRRFDAVLHDTDTRVKLADVAADPPLLAAARLVASRQGFTVRPPVRGSGGG
                     RARDDLRAIALASGVRTRTVRLEGPWWTKDLGPMVAYHVTGRPVALLPLGRRYVVVDDG
                     RVTPLTADGAGRLRNEGVVLYRPLPERVRDVRGLLRFGFSPSHGHGRDLVRFVVAGGLV
                     ALLGLIIPVMTGEVLGSYVEAADRDLIVQGALAVIASGLVTAALSVVQNIAVLRMESRS
                     GAAMQAGLWNRLLSLPAAFFTRYSTGELGTTVLGVTAAQELLSGMLTTATLALLTGLAN
                     LGLVFWYDVTLALAAAGLTAVGVGFAAVAGRIQLRWARREYVHDQAMSSMVFQMLTAMP
                     KLRVAAAEERAFAEWTRLAAEGHALSARVRRVQNAVTTFNAGFPLVCSAVVFALTAGPL
                     HGEIPLSVFLPFYTAFNLLLAAGLQFTAAAVTAVGTVPMLERLQPILEAEPENDGTKAD
                     PGDLSGRIAVSHLSFRYGQDGPLVLDDLSLTVQPGEFVAVVGASGSGKSTLLRLLLGFE
                     TPLSGSVLYDGQDLAELDISAVRRQCGVVLQNGALQAGDILANIVGTTGFTLDEAWAAA
                     EMAGLADDIRAMPMGMHTMLSEGTNTLSGGQRQRLMIARALVARPRLVFFDEATSALDN
                     PTQSLVAESTRRLNATRLVIAHRLSTVVDADRIVVMERGRIVQQGTYDELMADTDGLFA
                     RLAGPQLSTSARFSRAGAE"
     gene            20256..20438
                     /locus_tag="N6J21_RS20515"
     CDS             20256..20438
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N6J21_RS20515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_093723147.1"
                     /transl_table=11
                     /translation="METNPTTRGRINWLLPAVYALAIVVAGAVFSGAAAGVTAAVGGVL
                     LGLYYGFGNRLGLRR"
     gene            complement(20446..21627)
                     /locus_tag="N6J21_RS20520"
     CDS             complement(20446..21627)
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (33-388). E-value:
                     3.9e-70. Score: 228.7. Matches aSDomain:
                     nrpspksdomains_N6J21_RS20520_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015658950.1"
                     /locus_tag="N6J21_RS20520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_250752543.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.6e-68, bitscore:
                     228.8, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 2.1e-10, bitscore:
                     38.9, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.4e-07,
                     bitscore: 29.9, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSVRPLLNRRLAEFGTTIFAEMSALALRTGSINLGQGFPDTDG
                     PEEVREAAVRALRDGRGNQYPPGPGVPELRLAVAAHQERLYGLTYDPDTEVLVTAGATE
                     AIAAALLALLEPGDEVVALEPYYDSYAACIAMAGARRVPVTLRPDGGRFRLDLDELRAA
                     VTDRTRLLLINTPHNPTGTVLTREELAAVAELAVERDLLVVTDEVYEHLVFDGAEHVPL
                     ATFPGMRERTVTISSAGKTYSFTGWKVGWVTAPPALVTAVRSAKQFLTYVASGPFQYAV
                     AEALALPDSYYADFRADMQAKRDLLASGLKEAGFEVFTSAGTYFITTDIRPLGESDGFA
                     FCRALPERAGVVAIPNAVFYDHKDAGAPYVRFAFCKKAEVLEEAAGRLRRLVP"
     aSDomain        complement(20464..21528)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_N6J21_RS20520_Aminotran_1_2.1"
                     /evalue="3.90E-70"
                     /label="N6J21_RS20520_Aminotran_1_2.1"
                     /locus_tag="N6J21_RS20520"
                     /protein_end="388"
                     /protein_start="33"
                     /score="228.7"
                     /tool="antismash"
                     /translation="INLGQGFPDTDGPEEVREAAVRALRDGRGNQYPPGPGVPELRLAV
                     AAHQERLYGLTYDPDTEVLVTAGATEAIAAALLALLEPGDEVVALEPYYDSYAACIAMA
                     GARRVPVTLRPDGGRFRLDLDELRAAVTDRTRLLLINTPHNPTGTVLTREELAAVAELA
                     VERDLLVVTDEVYEHLVFDGAEHVPLATFPGMRERTVTISSAGKTYSFTGWKVGWVTAP
                     PALVTAVRSAKQFLTYVASGPFQYAVAEALALPDSYYADFRADMQAKRDLLASGLKEAG
                     FEVFTSAGTYFITTDIRPLGESDGFAFCRALPERAGVVAIPNAVFYDHKDAGAPYVRFA
                     FCKKAEVLEEAAGRL"
     gene            21773..22126
                     /locus_tag="N6J21_RS20525"
     CDS             21773..22126
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609567.1"
                     /locus_tag="N6J21_RS20525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_261719014.1"
                     /transl_table=11
                     /translation="MVVGFILVIFFVVVAGGITVAVLAAGRRRVAPLRGVRGVHGGGRG
                     GGGGSSHHTRHSSGDSGSWWAGDSGGDSGGGGSSCGSSSSCGSSSSSCGSSSSSCGSSS
                     SCGGGGGCGGGSS"
     misc_feature    21792..21806
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.61"
                     /tool="antismash"
     misc_feature    complement(21794..21805)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.54"
                     /tool="antismash"
     gene            22479..23015
                     /locus_tag="N6J21_RS20530"
     CDS             22479..23015
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015658948.1"
                     /locus_tag="N6J21_RS20530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2617 family protein"
                     /protein_id="WP_093723133.1"
                     /transl_table=11
                     /translation="MLTTLNTSYTDTRAADLAWALGREPLPALATLDLELSGAKLQLRL
                     LGASHQVLLEEERGDCSETVACIPGSSTPLPLGVAKRVGDWEYEFAARVEVLAPGQFAG
                     RAQELLALVADHPHGLAGVFPGSPHAFTAMLAHRHEGQLHWRTWHAYPQDGQLVATRTR
                     VGVRVPVGALSPSGV"
ORIGIN
        1 gttcctcgac gcgcacgccg agcaggcccc gccgtccccg ctcgcccggc tcgccgccga
       61 cccccggctc acccggcagg agatgctcgg ggtgctcggt ctcgccgtgg tcggcggctg
      121 gcagccgctg gccgagtcca tcggcaacgc cctgtactgg ctgctgccca gccccgacgc
      181 ccgggccgcg ctgcgctccg ccgacgcgga aggcgcgctg acggccatgg acgaactgct
      241 gcgcctggag gcgccgatcc ccttcacggc acgggtcacc ctgcgcgagg cgaccctgcc
      301 gggcggcacc attcccgccg ggcagcgggt gcttgcggtg ctcgcggcgg ccaaccgcga
      361 cccggcggtc ttcaccgacc ccgccgagcc ggtcttcgac cgcaccccca acccccacct
      421 cgccttcggt ggcggccccc acttctgcct cgccgcccgc ctggtacgcc aggcaggcgc
      481 cctcctcctc acccgcctgg tccaccgctt ccccgacgcc aaccccggtt cgtcgacacc
      541 gagttgggcg ccgacgctga ttccgcggcg gatcacgggg ctgagcgtgg agctgggggc
      601 cgacgcgggc accgggcgat gtcccgtgac gggggcgggg gtcggcgcat gagcgaagtc
      661 gtggtgatcg gggcggggtc ggcgcatgag cgggggttcg ggagtgtctg aagtcgtggt
      721 ggtcggggcc ggggtcgccg ggctcgcctg tgcggtgcgg ctggccgagg ccggggtcga
      781 cgcacaggta ctggaggcgc ggtcccggac cgggggacgg gtacgcagct tccggcccgc
      841 cgacggaggg cccgccctgg aactgggggc gcagatcgtg cacggggacc gcaaccccgc
      901 gcacaccgtc ctcgggccgc tgcccgcgtt gccccggccg acggcggcgt acgtcgtcag
      961 cgggcgcacg gcgcggccga tggcgctgct cgcccgtggg ggctgcccgc cctggctggc
     1021 ggaggcccgg ctcgccgcgt accgggaggg ctccgtcagc gtcggctcct ggctgacgac
     1081 cctcggggcg gctccggccg aggtcgcggt ggcccgggag tggttccggc agacctgggc
     1141 ggccgacccg gggcggatcg acgcggcggc ggcggggctg gcgatgcgtc aggacccggg
     1201 agggcgaggc gagttcaccg cgcccggcgg gctcgatgtg ctgaccgcgc ggctggccga
     1261 gcgcgttcgg gtacgcaccg gcgttccggt gcgccggatc gcggtggagc cggacggctc
     1321 gggcgtacgc ctggccaccg aggacggcga gacgaccgcg tcgcaggtgg tcgtcaccgt
     1381 gccgcccgcc gtcgtggacc gcggactgct caccatcgac gggctcgacg aggaccgacg
     1441 ggccgccgcc cgcaccctcg cccccggcga cgcgtactgc gccgtcgtca ccctgagcgg
     1501 ccccgcaccc caggacatct cggtgttcga cgccgacggc gcgggcgggt tcctgtcctg
     1561 ccggcgcggc cgtcccgagg tgacgctcgt cgccaaggac accgcggcgg cctgcgtacg
     1621 cgcggcggcc ggctccgccg gacaactggc ggccctgctg gcggtggcgc tgccgtggac
     1681 cgccgccctc gacatcgtgg ccgtcgagac ggcggactgg tccgccgagc cgttcagcgg
     1741 cggcgggttc tgcgcgcccg gaccggactc gacggcggcg gccgagcgct gggcgcgtcc
     1801 gctgggcggg cggctgttct tcgcggggga ggccgccgtg acgggccgcg cgctgccgtg
     1861 gctgcagggg gcgtacgccg acgggcggcg ggccgccgaa gaggtactca aggcaaggaa
     1921 gcagggacag tgaacgtcca ctcgggctgg tacttggccg ccttcacctc cgaactggag
     1981 ggcgacgtgg ccccgttgga catcggcacc cgacggctgg tcgccgtgcg gaccggcggt
     2041 gcgctgcggg tctacgacgc ggactgcccg caccgcggcg cccatctcgg gcgcggcggc
     2101 cgggtcgagg gcggctgtct ggtctgcccg ttccacggcc gccgcatcgg cctgggccgc
     2161 ccggagcggg agggcccgag gccgtgggtg cgggagcacg aggtgatcgt gtgcggcgag
     2221 gccgtcttcg tgcggctcac cgacgggccc gacgacgacc gcgggatgcg cgccacgctc
     2281 aaggagctgg ccggcaccca cccgctggtc cgggcggtcg cccgccccgt cgcggccgcc
     2341 gccgacctga tcgtcgagaa cgccttcgac accgagcact tcaccgccct gcacaaggtg
     2401 taccgggtgc gcggaatgcg ccaccgcgac ggtgcccacg gtgagttggt gatggacggc
     2461 gagttcccga tgcccgcctc gccgtggcgc ggcaggcccg gcgcgcccgc cgccgaaccg
     2521 tacgtcccgc gcttccacgc gcgtgccttc agccccgccg tggtggtgac cgagttcgga
     2581 cccgccgacg aggtgcacat catcgtcacc ggcgcggtgc cggacgcctc gggcggctgt
     2641 gtcgcccggg tcgccatcgg ggtgcgcgag ggccaacagg ccgcgctgcc cgccctgatc
     2701 gcgggcagcg agcgcgcgct cgccgaggac atcgacgtat gggagcacct caatcccgcc
     2761 gtggtgcccc ggtacgacga ggcggacgcg gccgtggtcg cgtaccgggc cttctgcgag
     2821 ggcttcaccg acctcggcac cccgggggcg tcatgaccgt acgccgatgc gccaccgacc
     2881 ccgactgcgc cgcctgtacc gccgcggccg ggccactgcc gggggagacc ggggcgaccc
     2941 gcgacgggct gcgcgtacgc acctggggcg gggacggccc caccgtgctg tgggtgcacg
     3001 gctacaccat ggacgccacg ctctggcgcc ccctgtggcg tctgctgccc gggctgcggc
     3061 acgtcggtgt cgacctgccc ggccacggcg gctccgcgcc cctggacccc ggcacgacgc
     3121 tgcccgcgct ggccgcccgg gtgctggagc tggcccgcgc cgagggggcg cggcgctggg
     3181 tgggcctctc cttcgggtcg accgtgacgc tgcagatggc cctggacgcg cccggcgccg
     3241 tggaccggct ggcgctcggc gcgcccactc cggccggcgg accgccggac ccggccgccc
     3301 gcaagcggta catcgagctg ctgatgctgc gccggatgcg cggcccggcc gccgccgacc
     3361 agctggccga cctgtggatg gcctcgcccc ccgacatctt ccggggcacc gaggcgcacc
     3421 ccggcctgcg gtcccgcatc cgggccgtgg tggcccgcca ctcctgggcc gaactcgaca
     3481 acggcgccat ggccgcgctc agcgcccaca cccacccgcc cgaggacctg tcccggatca
     3541 ccgccgacac cctcgcgctc accggcgccg acgacatgcc ggtctttcac tccaacgcgg
     3601 ccctgctggc ggtcgagttg ccccgctgcc gtacggaagt ggttccggac gcgggtcatc
     3661 tgccgtttct ggaacgaccg ttggcggttg caccggttct ggccgcgcac cttgcgggcg
     3721 ggccggtgag cacagagcat gtacgggacc tgcgcgcgac gaccacaaac gcaccgagaa
     3781 tcaaggaatt tatgggcgag gagccgcctg tatagagtga tcgaagacca aacgggggct
     3841 agggggacat gccggaattc gtgcttgagt tcttcgggac actgcttcat gtaacgggga
     3901 tggaaggccc cgaactgtcg tacttcttcg ggccgcatct gctcggactg cgcaagacgc
     3961 cggagaagga gaaggcgtca ctgaccgtgc acctcggaca gcggtccggg tcgggcgggc
     4021 gcggggtgcg ggtgttcggc ccggacggaa ggctgctgcg ccgctggtcc ttccacggca
     4081 tggggggcat tccgccgctg ctgccgccgt tcgcggcgat gaacgggcag tacgcggtgg
     4141 tccaggcggc cgtgctcgcc gagggcgacc gggtggtcgc gctgatcggc ggcgtcggct
     4201 cgccgcgcaa ctccgtcgcc ctcgccctgg gcgggcgggg ctggcggatg gtgtcgagcc
     4261 agtacctggt cgtcgaccgt gccaccgggc acacgctgcc gtaccaactg cccatggaac
     4321 tgcgcggtgt cgacctggac gcggtgcgcg ccgccggtct cgccgacggc ccggacgccg
     4381 tcgacgcaac gcccggcggt cccaccgcac tgccgggtct cggcgccgcc gaggacgggg
     4441 gcgcgtacgc ctggagcggg gacctgcgcc gggtgcagtc gccgctgacc ggcccgtacc
     4501 tccaggtccg tcccgagcgg ctgctggcca ccgtggaccg gggcgcccgc ctgggcccgg
     4561 cccatctggt gcggctgtgc tgcaccggca ccgaccgctg cgagctggag gagtgggacg
     4621 tcaccccgtc cgtctggccg ccggaggccg ccgacggcct gcccgcggcc tcccgcctgc
     4681 ggctgctgct gcccggaacg cgcagcgccg acgaggccgc cgacctgctc cacgaacgac
     4741 tgacgtcact gcccgccgcg aagggaaccg tcctgtgccc cgccgaacct cgtacaccga
     4801 gggaacaccc tgctggatcg accacgtggg ggtcgacccg accggcgcca aggagttcta
     4861 cacagccctc ctcggttggg agttccgacc cgagggcggc cgtggctacc acctgatcct
     4921 gctcggcggc gagatcgtcg gcgggctcgg gccgagcccg atgggccccc ggttcgggtc
     4981 gtcctggaac gtctacctgg ccgcgaagga cctcgacgcg gccggggaac gggccgagcg
     5041 gcacggggcc cggctgctgg cgcggggcgt cccggccggc ggggacggca ggctgagcct
     5101 ggccgtcgac ccgcaggggg cgccgttcgg tctgtggcag ggcatgcgcg aggagggcgt
     5161 cgtcctcgtc gacgagccgg gcgccctggc cggcgcggtg ctgcactcgc ccgagccgga
     5221 ggactcggcc gccttctacg gggccgtgtg cggctcggac gcccggatcg agaagggctc
     5281 cccggcgcgg tggatgccgc tgctcggggc cgacgccccg gacgccttcg aggagcgggc
     5341 gcgggccgcg ggggcgacgg tgctcgcgcc cggggtgctt gccgacccgt ggggagcggt
     5401 gttcggggtg gcggacgtgg cggtgccgcg gtaggccgtg tccgcgaccc ggcgggcggg
     5461 cgcggcgcgt acgtatcgcg cgcgatacgt aatatccgcg ctgcgcaccg ctgtccgttc
     5521 tccgggccgt gcttcccgtg ccagggtctt gggtggggag cgaaattccg cgcgccgcga
     5581 gattccggtt cgctgtcccc tgcggaattt ccgtacggaa ttccagtgcg gcacgcggct
     5641 gtcatgccac cgggggaagg gaaacgaatg gcacccgaaa tcgtggtgat cggcggtgga
     5701 ccggccggtt ccatttcggc ggctctgctg gcccggaacg gtgcgcgggt ccggctgctg
     5761 gaacgcgcgc atttcccgcg ctatcacatc ggggagtccg tggcgacgtc ctgccgcgcc
     5821 atcatcgaac tcgcgggcgc gctggagaag gtggacgcgc gcggctacca ggtcaaggaa
     5881 gggctgctgc tgcgctgggg cgccgagcgc gactgggtgg tcgactggcc ggagatcttc
     5941 ggcaccggcg cacagacctc gtggcaggtg gaccgcgccg acttcgacca cgtcctgctg
     6001 cggcacgccg cctcccaggg cgccgaggtg accgagggcg cccaggtcaa gcgggtgctg
     6061 ttcgaggacg gccgggcggt cggcgtggag tggacgcacg agggcgtcac gagcaccacg
     6121 cgcgccgacc acgtcatcga cgcctccggg cgggccgggg tgctctccgc gcgccacttc
     6181 cgcgaccgcc gccagcacga cgtgttccgc aacgtcgccg tctgggccta ctacaagggc
     6241 ggcagcctgc tcccgcgcac cccgcgcggc ggcatcgacg tcatctcctc gccggagggc
     6301 tggtactggg tcatcccgct ggcggacggg atgttcagcg tcggcttcgt gacccaccag
     6361 gacaacttcc tgcggcgcag gcaggactgc cccgacgtgg agcggctgtt cctcgacttc
     6421 gtccaggagt ccgacaccgt gcgggagttg atggccgacg gggagttcca gcacgacgtg
     6481 cgcgtcgagc aggacttctc ctacgccgcc gacagcttct gcgggcccgg ctacttcctc
     6541 accggggact ccgcctgctt cctcgacccg ctgctgtcga ccggcgtcca cctcgccatg
     6601 tacagcggca tgctctccgc cgcctcgatc ctcgcgctgc acgacgggga cgtggccgag
     6661 ccggaggcgc tgtccttcta cgagacgctg taccgcaacg cctacgcgcg gatgttctcc
     6721 atggtcgcgg gcttctacga gcagtaccgc ggcaaggcca cctacttctg gctcgcgcag
     6781 cggctggccc gcggccgcta cccggaactg gtgcgccgcc ccgagcccgt gccgatgcgc
     6841 tcggcgccgg acagcgaggc cttcgcggcg ctcaccgccg gcgccctcga cctcgacgac
     6901 gcccgccggg cgggcggcgc ggatccgctg gccgcggagg tactggcggc ccaggtcgcc
     6961 ccgcgcgcca ccgcccgcga ccgcttcgac gccgccaccg gcctgtacct gcgcaccgag
     7021 ccccgcctcg gcatcggccg cgtcaccgag accgcgcgca cctgatcccc cgcaggcgcg
     7081 cgcaccgggc gggggcaccc caagacttgg gcgcccccgc cctttcctgt gcccgcggca
     7141 cgttgtccgg gtccggttca ccgggcgggc ggggcgcgcc tgttgtgtcc gtccgccggc
     7201 acccgtccgc tacggcacgc tcagggccgc cgccagttcg tggcggctgt ggatgccgag
     7261 tttgcggtag acgcggccca ggtgggtgtc gaccgtgcgc ttgctgagga acaggcgctc
     7321 ggagacctcc aggctggagt ggccgcgcag gaccagttcg accacgcgtt gttcggcggg
     7381 ggtcagcgtg gggcgctcgg ggtcgtgggg tgcggacgcc gggtgcgggg tgacggccgg
     7441 ggtacgaggg ccgccgttca ggatcgtcgc cgcggccgcc tcctcgccga gcgcccggta
     7501 cgcccgcgcg gcctgcgtcc gccagggcag acaggcgggg ttggtgatgc cgcgcagggc
     7561 gagccggtgg ccgcagtcga ggaacaggcc gagggcggcc gtgtggtccc cgcgcgcggc
     7621 ggcgacctcg ccccgcgctt gcagggagag cgcccgcacg aacgggtgca ggtcccccgc
     7681 cgaccggtcc tcgcgcagca cctcggccgc gtcgtccgcc cggtccagac ccaccagcgc
     7741 acgcgccgcg caggacaggg cggcgctggt cagcgcggcg gcgttcagcc ggcgggccag
     7801 cgcgagcccc gcctcggcgt cggcgtacgc ggtggagaac ctgccctccc ggtggtgggc
     7861 ctcggcacgc accaggcggg ccagcagcac ggtggccccg tcgtcggcgg cgcgcgcggt
     7921 ggtgagcaca cgcgtggcca ggtcgcgggc ggcggcgggg gccccggtcc agatcagggc
     7981 cagtgccgcg ccgatgggcc cggccggcca gcccgccgtc acggcctcct gggcggcgcc
     8041 ctgggcgacc tccacacggg cggccagccg ctgcgcggtg ccggtgcggc cggtggcggc
     8101 ggccgccgcg gcgagcgccc cgctgaagga gcgcgccgcc gggtccaggg gacccctggc
     8161 cgcgagccgg gcggcggccc gtacccccgc gcgatgcccg gtgagcagcg cctgcgcggt
     8221 caggcggagc agcggctcgc ggggcggggc ggcgagcgcg gccagctccc cgcaggcccg
     8281 tacgaagggc tgggcgccct ccagcgaggc gaccagggcg ggggaggcca gccgggccag
     8341 cacctcggcg cgcccgaccg ggccgggcgc gctgtcggcg gcggccacgg tctgccgggc
     8401 gcaggcgtcc aggtcgcggt ggagctcgac ggaggccagc cgcacggtca attcgtggaa
     8461 ggtctcggcg tgcggggtct cgccggggcg ctccggcgcc gacgcgtccc ccgggggcgg
     8521 cccgtccagc agggcgaggg cgcggcgcag atagcgcgcg gcggaggcgt ggtcaccggc
     8581 cgcggcggcc tgcgcgcccg cgtcgcgcag gacgtccagg ccccactcgc agccggcctt
     8641 gaccaggtgc tcggcggtct gccgggccgg ggcgccgagc cgggccagca ccgtggcggc
     8701 gcgcccgtgc agatgcagcc ggtcctcggc cggtacccgg gccaggaccg cgggccgcac
     8761 cgcggcgtgc gggaagcggg cgggcggccc ggcctccagc agcccggccc gtaccagcgc
     8821 gtccctggcc tggagcacct gcacctcgcc gtgctgggag agcgccccgc acatggcggg
     8881 gtcggtgtcc gggccgagta cggcgagctg ggtgagcagt tcaccggcgg ccgggtcgtc
     8941 ctcgtcgagc caggccagca cggtctcgga gagcgcctgg gcgccgatcg gcagcacctg
     9001 ctgggggtcg ggtgcgccgg gcgggacgtg ctcgcggcgc agccggttca ccaggtcgtg
     9061 cagcaccatc gggttgccgt gcgcgagggc gtcgcacagg gcggccagcc cctggtcgac
     9121 ggggctgtcg aaggcgcggt cgacgagttc cgtcgtacag gtcgaacaga gcggttccgg
     9181 ccacagccgg tacaggtacg gcagcgggcc cagttcgtcg gtcagccgcg cggcggcgga
     9241 gtcgggcagc gtcgccacca gcaggaccgg caggtcgtcc agtcgccggg cgaggtagga
     9301 gaaccagcgc agtgagggtt cgtcggcgta ctgcagatcg tccacgagga cggcgacggg
     9361 ccggtcggcg gcgagcgagc gggtcgtgct cagcaggtgc agcagggcct cgtgggtggg
     9421 tccggcggcc tcgccggagg agccgtggcc ctcggcggga atgaacgttt ccgcccgtcc
     9481 ggcggccccg agcacggggt cgaagagctg gcgcaccatg ctgtacggaa acccgctctc
     9541 gctgggatgg cagcgggccc gcagcaccag ggcgccctcc gggaggagcc gtggaaccac
     9601 gttcagcagg gccgacttcc ccatcccgcg cggtccgtgc acggtgacca cggcaggccg
     9661 gcccagagcg agcccggcga tgacctcctg aaggagggat atctcgcgct ctcggtgata
     9721 cagatccccg ttgactgcat gcattgcgcc aatcttgcat tccattcggc caggagcaag
     9781 cgcccttgcg cggcaacgga cttggcccgg cgatacgtac gcgacgcccc gcgagaagta
     9841 cgtatgggcc gtccggttgc gtagtgaatg aagcatttac ccgccgtgca cgccgtgttt
     9901 gggtgaaccg tgccggaaag cgccggacgt cgcacgacgg acgggtcgag gcgcgccgcg
     9961 ccaactcgcc gcacatgcat cggaagaacc agggggaccg atggaaaagc cgcgcctgaa
    10021 agcgcatttc cacgtcgagg tggtggaggg cgagcgcgtc ttcctctatg ccgagggcca
    10081 ggactacctg gtgccgggca aggcggcggc ggccgtcgtg ccgtacctcg acggccgcag
    10141 gaccgtgatg gagatcgtgc aggcgctgtc cggcaccgtg gccatcccgg ccgtgctcgg
    10201 cgccctcacc cgcttcgagg cggccggtca tctcgccgag gggcgcccgg agttggacga
    10261 gtccgtcctc gcctactggg acgccctcgg catcgacccc gccaccaccc tcggcacggc
    10321 ccccgtcacc gtctccgccg cgcccggcgt cgaccccgag ccggtggtca ccgccctgcg
    10381 cggcctcggc ctgaccgtgg ccaccgcgcc gctggactcg gtgcccgagg ccgggctgtc
    10441 cgtcgtcctc gtcgacgact acctcgaccc ggcgctcgcc gcccgcaacg accgccaact
    10501 ggccgccggg ctgccctggt tgctggcccg ccccgcgggc gtcgcgccct ggatcggccc
    10561 cttcctcaag cccgagcaca ccgcctgctg gcgctgcctg tcccaacggc tcaccggaaa
    10621 ccgccagttg gagcgctacc tggccggccg gcgcggcgag tcggtgcccc gccacccggc
    10681 gcgcgcgggc atcgccgccg gaccgctggc cgcggccggg ctgctggccg ccgaggccgc
    10741 gcggatcgct gccaccggcg aaccgggggc actgtgcggg cagatgatca ccctcgacct
    10801 ggccaccctg cgcaccgaga cccaccccct ggtgcgccag ccccagtgcc cctcctgcgg
    10861 cgacccggcc ctggtcaccg gccgcagccc caaggtcgtg ctcagctccc aggaggcccg
    10921 gcacaccagc gacggcggct accgcgtgaa ccggcccgag gacaccctcg cccggctcga
    10981 acggcacatc agcccctact tcggcgccat caccaagctg gtctcgcaca cccccgagtc
    11041 caacacgctg acctacagct actcggcggg ccacaacttc gcgatggtca acgacagcct
    11101 ggacctgctg cgccgcaatc tgcgcggcca gagcggcggc aagggccgct ccgagatcca
    11161 ggccaaggtc agcgccgtgt gcgaggcgat cgaacggtac gtcggggtgt ggcgcggtga
    11221 cgaacccgtg gtgcgggccg cctaccgcga cctcgacgcg ggcatcgccg tgcaccccag
    11281 cagcctgctg cacttctccg aggggcagtt cgccgggcgc gcggagtgga acaaggaccc
    11341 ggccaaccgg ctgcacaagg tccccgaccc gttccccgag gacaccccgg tcgactgggc
    11401 gcgcggctgg tccctcaccc atgacgccga gcgcctggtc ccggcggcct actcctggta
    11461 cggccacccc gacctggacg acaacttctt ctgcatcgcc gactccaacg gcagcgcggc
    11521 cggcaacacc ctggaggagg cggtgctcca ggggctgtgc gagctgaccg agcgcgacgc
    11581 cgtcgccctg tggtggtaca accggctgcg ccgccccgcc ttcgacatgg actcgctgga
    11641 cgacccgtac gtgacgcaac tgcgcgccca ctacgaggcg atggaccgcg acctgtggat
    11701 gctcgacatc tccttcgacc tggggatgcc ggtgtacgtg gcggcctccc ggcggcggca
    11761 cagcgtcgag gacatcatgg tcggcttcgg cgcccacccc gacccgcggg tcgccgcgtt
    11821 ccgggcgctg accgagctga accagttcct gccgatgatc gagcagcgcg acgcgcaggg
    11881 caacacgtcc tacctggtcg acgacctgga gacgctgacg tggctgaagg aggccaccgt
    11941 cgagcgggag ccctggctgc tgcccgaccc cgagctgccc gccgtccggg tcggcccgcg
    12001 ggccgggttc gacctctccg agcgcatccg cgagcaggtc gagcggatcc gtgaggccgg
    12061 ctccgaggtc atcgtcctcg accagacccg ccccgacctg gaactccacg tggtcaaggt
    12121 gatcgccccg gggctgcgcc acttctggcg ccggctcggc cccggccgcc tgtacgacgt
    12181 acccgtccgt ctggggctgc tggagcggcc cacggcggag gcggacctca accactggaa
    12241 cgtcttcttc tgaccggacc ggcgtacacg gccccgcacc cgcggtgccg tgtacgcggc
    12301 atgccgccgc accgttgcgg cccgcgcttc caccagggag gaagccatga cgatcacgac
    12361 cagcccactg acgacggcgc gggacggcgc cgacagcacg cccgcgccct gcaccgaggc
    12421 gatccgcctg acccgcggcg ccaccttcga cggggagcgg atcaccgccc ccttcgggac
    12481 cctgcggctc aaggaactgc cctccggagc acgggccgcg ctcaccgcgc tcgccgggga
    12541 ggacctggac gaggggcgga tcaccgcgct cgtcgtcgcc ggggacggcg aggcggggct
    12601 gctgcgctgg cacatgctgc gcacccggct ggacaacacc ggcctgctcg aacactccgt
    12661 gaccggagcg gacggcacga ccttggcccg gctggtcacc gtcgggcggg gccgcaccac
    12721 cctgcgcccg gtaccccgcg acgccgtacg cctgtcccgg cacgccctgc tgctgcccgc
    12781 cgacggcacc ctgtccctgc gcgcccccgg cagcccgctg gccgtcgaac tcgggcccgc
    12841 cgcggccccg ttcctggcgc ggctgaccga ctggaccgac gccgcgcgga taccggcgcc
    12901 cctgctgcgg ctgatcgcca cggccggagc cctcaacccg ggcacccccg aggacgaccc
    12961 ggagcgcgag cagcgcggcg gggtccagtg gcacccgctg gacctggctt tccacacccg
    13021 cacccgggtc cccgcgtcgg tcgccggcta cggcggcacg tacccgttcg ccgaccggtt
    13081 cccgcccgaa ccggtcgccg cccccgcggg cgacgggccg cgcgtgccgc tgcccgtgcc
    13141 cgacctggac gagatcgccg cccgggaccc ctcgctcacc gaggtcatcg agagccgcac
    13201 ctccacccgc gcccacgacc ccggatcgcc cgtgacggtc gatcagctcg ccgagctgct
    13261 ctaccggacc gtgcgcatcc gcgccacgtt caccggcggc gacggccagg agctcgccga
    13321 ccgtccgctg cccagcggcg gcagcgtgca cgagctggag gtctacccgc tggtcacgaa
    13381 ctgcgcggga ctggcgcccg ggctgtaccg ctacgccccc gaccggcacg agctggagct
    13441 ggtccgcgag ccgggcccgg ccaccgaacc cctggtcagg gaggcccgcg cggccacgat
    13501 ggcggacgac gacccgcagg tcgtcctcct cgtcgcggcc cgcttcggac gggtgatgtg
    13561 gaagtacgag acggtcgcct acccgctgat cctcaagcac gtcggcgtcc tctaccagac
    13621 cgtctatctg gtggccacgg ccatggggct cggcgtgtgc gggctcggcg gcggcgacac
    13681 ctcggcgttc gccgcggcga ccggctgcga tccgctgctg gagggcaccg tcggtgaact
    13741 cgtcctcggc acacccaggc tgacggcacc cggcggcccg gccgaccggg aggagtgacc
    13801 ccgtgcagtt ccgctaccag gccctgcagc gcaagcggga gccggacgag ctggacgcgc
    13861 ccgtgctgct ggcggcgccc cgcggctgga tcgccgtctt cgtcgtcctg atcaccatgg
    13921 ccggcgcctg tgtctgggcg gtgttcgccc ggctcgaagt gaccgtcgac gcccccggca
    13981 tcctcaccca ccccggcggc accagccagg tccagagccc gtacaccggg ctggcccgcg
    14041 agctgctggt gcaccccgac gacgaggtga aggcggggga cccgctcgcc cggctcaccg
    14101 acgacgcggg ccgcgtccgt accgtcacca gcccgttcgc gggcaaggtg atcagcgcgg
    14161 cgctgacgtc gggccagttc gtccgggcgg gcagcaccgt cgccaccgtc gaacgcaccg
    14221 acctgcccga cgaccggctc gtcgccctcg tcttcgtccc cgccgaccag gccgccgggc
    14281 tgcgccccgg ccgccccgtc gacctgtcgg tgtcgaccgc gccgccgtcg gtctacgggc
    14341 tgctgcgcgg cgaggtcacc tcggtctccc cctacccgct cacccgcgaa gggctggccg
    14401 ccgtcgcggg cggcgacctg gcggccgagg ccttccacca ggaccaggcg ccgcgcctgg
    14461 tcacggtgga cctgatcccc gagccgggct ccccgtccgg ctacgcgtgg agcaccgccc
    14521 aggccccgcc cgtccggctc ggctcgcaga cctcggtgag cgcgtcgatc gggctgcgca
    14581 gccagtcgcc gttcgccctg ctgctgggac gctgaggagg ccggaccgat gagcgacacg
    14641 aagtcgacca ccgccacccg tacgaccgga ccgggcggcc cgccgggcgg ccccggccgg
    14701 gacgcgcccg tctcgccccg ccgcgcccgc cgcgccgaac gccgcggcag gcgcggcgcc
    14761 gcccgcgaac gccgctgggc ccgccgccgc gcccaccggg tgcccaccgt cctgcagatg
    14821 gagtcggtgg agtgcggcgc cgccagcctg gcgatgatcc tcgcccacca cggacggcac
    14881 gtcccgctgg aggaactgcg ctccctgtgc ggggtctccc gggacggcgc caaggccagc
    14941 tccgtcctgg ccgccgcccg ctccttcggc atggtcgccc gcggcttcca ggccgaaccc
    15001 gatctgctgc gcgagaagct gcgcaccgga ccggtgatca tcttctgggc gttccagcac
    15061 ttcatggtgg tcgaggggat cagcacccgg ttcggccgca ccctcgtcgc cgtcaacgac
    15121 ccgagcaccg gcccgaggct gatggagtgg tcggagttcg actcgggctt caccggcatc
    15181 gtgctcacct tcgaacccgg ccccgacttc cggtccggcg gacgccgcac cagcaccgcc
    15241 gccgccctgc tcgaccggcg gctgccgtcg gggcgggcgc tgccgctggt gctgctggcc
    15301 agcctgctgc tggtggtgcc cggcatcgtc ggcgccgcct actcccgggt cttcgtcgac
    15361 caggtgatcg gcgccgactc gtccaccgcc gtgctcccgc tggccgtggc gatggcggtg
    15421 accgcgctga tggtcttcgt gctgacctcc gtccagcagc actacctgct gcgcatggag
    15481 atccgtaccg gcctggtcag ctcggcgcgc ttcttccggc atctgctgcg gctgcccatc
    15541 gagttcttcc tccagcgccg ccccgccgag gtcgccaaac gggtcgccag caacgacacc
    15601 gtcgcgatga tcctctcccg cgacgtcgcc gcgaccacca tcaacctgac cctggtcgtc
    15661 ttctacggcg ccctgatgat ccgttacgac gtgctgctcg gcgccatcgg cctggccacc
    15721 gccggcctga acgtcctgat gctccagctc gtcgcgcgct cccgcaagga cgccgtggcc
    15781 gccctccgcg ccgaccgcgg caacctgatc ggcaccacct tcgcgaccct gtccaccatc
    15841 gagtccgtca aggcgtccgg gtccgagccc gaggcgttca cccgctgggc cggcttcctc
    15901 gccaaggtca ccagcgccca gcagcggctc gggcagacca ccgcggtgct gaccgtgctg
    15961 ccgccgctgc tcgccgtcgt caacatcggg gtgctgctgc tcgtcggcgg cctgcgggtg
    16021 gcggacggca cgctcagcgt cggcatcctc gtcaccttcc agaccctgct cgccgcgctc
    16081 agccgcccgg tcacccagct gaccaacctg ggcagccggc tccaggacat gaacgcggac
    16141 ctcaagcgca tccacgacgt ggagaagtac ccccaggcgg gctgcttcga gccgggtcgc
    16201 gacgaactcg accccgaggc ccccgagggc cgcctcaacg gcgaactcgt gctgcgcgac
    16261 atcaccttcg gctacggacc gctcgccgct cccgtcatct ccggactctg cctcaccatc
    16321 gcccccggtt cgcgcaccgc ggtcgtcggc ggctccggca gcggcaagtc caccgtcggc
    16381 cgcctcgtca ccggcctgta cgaaccgcgc tccggccagg tgctgctcgg cggacgcccc
    16441 cgcgaggaga tcccgcgcac ggtgctcgcc gcctcgatgg cctacgtcga ccaggacgtg
    16501 gccctgttct ccgggaccgt ccgcgagaac ctcaccctct gggacgacac cgtgcccgac
    16561 gaggtggtac ttgccgcgct ccaggacgcg gccgtcttcg acgaggtgct ctcccgcccc
    16621 ggcggcctca acgcccaggt ctgggagcac ggcgccaact tcagcggcgg ccagcgccag
    16681 cgcctggaac tggcccgcgc cctggccgcc cggcccaccc tgctggtcct cgacgaggcc
    16741 accagcgccc tggaccccgc gaccgagcgc accgtcatgg acaacctgcg gcggcgcggc
    16801 tgcgcctgtc tgatcatcgc ccaccggctg tccaccgtgc gcgacgccga cgagatcatc
    16861 gtcctggaca agggcaccgt cgccgaacgc ggcacgcacg acgaactgct cgccgcgcgt
    16921 ggcctgtacg cggccctgtt cgagtccagc agggccgagg agagtgacac gctgtgacga
    16981 acccggacaa cgcgcccgcc gccaccgcgg gcacgggcgc ctccgacaca ccgaccacgc
    17041 ccgcttcagg cgtgccgggc gggatcgccg ggggtggcga gggcggggcg ggcccggata
    17101 ccccgagcgc gggcgcggct gccgacgtga gcgtgcagac ttccccggac cacccgaccg
    17161 accccgctcc cgaacccccg ggcaccccca cccgtaccgt ctgcctggac gaccccggca
    17221 ctctgctcta cgtggcggag ggtgctgccg acctgttcgc ggtggaacgc gcggtcaccg
    17281 acgggcgggc cggggcagcg ggccccgacg acggcgacgg ggcggccggg cggcggcact
    17341 tcctgtgccg ggccgatgcc gggatgctcc tggtgtgcgg caccgaccgc gacacccggc
    17401 acaccgtcgt cgcccgcccc gtactcgacg cccaactgca ccggctgccg ctggaggtcc
    17461 tggacgacgt acgcgccggg cgcaccgcgc tgccccgggc ggacggggag cgcccggccg
    17521 aactcgacca cgcccgcgtc ctggacggtc tcaccgccgg cctcaccgcg ctcgccgagg
    17581 ccctcgccgg aactctgccg ccgcgcaagt tcacctccct gagcacccgc ggcagcacgg
    17641 aactcgaagc acgggacgtc acccgctccg tcgacggcgt ccgcttcgtc cgcgtggagt
    17701 ccgggctcct cgaccagggc gaccgcgcgg gcgcggagca acgggccccg gacctgcccg
    17761 aggcgcccga gccggtcgga ccgggcgacg aagtggtgct gaccgaacgg gactggctgc
    17821 gggcccgcga accggcccgg ctgacctccg cctcgctcct ggacgtctac cgccagggcc
    17881 gcctcaccgc cgcgctcgcc cgctacgccg tacgcctgcg cgccgccgtc gaccaccggg
    17941 tcgcggtcgt acgcgccgag gagcgggccg aactcgccgc ccgccgcgcc caggacgcca
    18001 ccgtgccggc cgccgcggtg cgccgcttcg acgcggtcct gcacgacacc gacacccggg
    18061 tcaaactcgc cgacgtcgcc gccgacccgc cgctgctcgc cgccgcccgc ctggtcgcct
    18121 cccggcaggg cttcacggta cggccgccgg tgcgcggcag cggcggcggc cgggcccggg
    18181 acgacctgcg ggccatcgcc ctggcctccg gggtgcgcac ccgcaccgta cggctcgaag
    18241 ggccctggtg gaccaaggac ctcggcccga tggtcgccta ccacgtcacc ggccgcccgg
    18301 tcgcgctgct gccgctcgga cggcgctatg tcgtggtcga cgacggccgg gtcaccccgc
    18361 tcaccgccga cggggccggc cggctgcgca acgagggcgt ggtgctgtac cggccgctgc
    18421 cggaacgcgt acgggacgtg cgcggactgc tgcgtttcgg tttctcgccc tcgcacggac
    18481 acggccggga cctggtccgg ttcgtcgtcg cgggcggtct ggtcgcactg ctcggcctga
    18541 tcatcccggt catgaccggc gaggtgctgg gcagttacgt ggaggccgcc gaccgggacc
    18601 tgatcgtgca gggcgcgctg gcggtgatcg cctccgggct ggtgacggcg gcgctgtccg
    18661 tcgtgcagaa catcgccgtc ctgcgcatgg agagccgctc cggcgcggcc atgcaggcgg
    18721 gcctgtggaa ccgcctgctg tcgctgcccg ccgccttctt cacccgctac tccaccggcg
    18781 agctgggcac caccgtcctc ggcgtcaccg ccgcccagga actgctctcc ggcatgctca
    18841 ccacggccac gctcgccctg ctgaccgggc tcgccaacct gggcctggtc ttctggtacg
    18901 acgtcaccct cgcgctcgcc gccgccggtc tgaccgcggt gggcgtgggc ttcgcggcgg
    18961 tcgccggacg tatccaactg cgctgggcgc gaagggagta cgtgcatgac caggccatgt
    19021 cctcgatggt cttccagatg ctcaccgcga tgcccaagct gcgggtggcc gcggccgagg
    19081 aacgggcgtt cgccgagtgg acccgcctcg cggcggaggg ccacgccctg tccgcccgcg
    19141 tgcggcgcgt gcagaacgcc gtcaccacct tcaacgcggg tttcccgctg gtgtgttcgg
    19201 cggtggtctt cgccctgacg gcgggcccgc tgcacggcga gatcccgctc tcggtcttcc
    19261 tgccgttcta caccgccttc aacctgctgc tcgccgccgg actccagttc accgccgcgg
    19321 cggtcaccgc cgtgggcacc gtgccgatgc tggagcgcct gcagcccatc ctggaggccg
    19381 aaccggagaa cgacggcacc aaggccgacc cgggcgacct ctcgggccgg atcgccgtct
    19441 cccacctgtc cttccgctac ggccaggacg ggccgctggt cctggacgac ctcagcctga
    19501 ccgtgcagcc cggggagttc gtcgccgtcg tcggcgcctc gggcagcggc aagtccaccc
    19561 tgctgcgcct gctgctgggc ttcgaaacgc cactgtccgg cagcgtcctc tacgacggcc
    19621 aggacctcgc cgaactcgat atctcggcgg tgcgccggca gtgcggcgtc gtactccaga
    19681 acggcgcgct ccaggccggc gacatcctgg ccaacatcgt cggcaccacc ggcttcaccc
    19741 tcgacgaggc gtgggcggcg gcggagatgg cggggctggc cgacgacatc agggccatgc
    19801 cgatgggcat gcacaccatg ctgtcggagg gcaccaacac gctctccggc ggccagcgcc
    19861 agcgcctgat gatcgcccgc gccctggtgg cccgcccgcg cctggtcttt ttcgacgagg
    19921 cgaccagcgc cctggacaac ccgacgcaga gcctggtggc cgagagcacc cggcgcctga
    19981 acgccacccg gctggtcatc gcgcaccgcc tgtccacggt ggtcgacgcc gaccggatcg
    20041 tcgtcatgga acgcggccgg atcgtccagc agggcaccta cgacgagctg atggcggaca
    20101 ccgacgggct cttcgcccgg ctggccggac ctcaactctc cacatccgcc cggttttcgc
    20161 gggcgggagc cgagtgagat gatcggaccg gcgcgacccc gcgccggtcc gcggcccgct
    20221 cccgcacgac cacgacctcg accccagggg gaaccatgga gaccaacccg acgacccgcg
    20281 gccggatcaa ctggctgctg cccgccgtgt acgcgctggc catcgtggtc gccggggcgg
    20341 tgttctccgg tgcggccgcg ggtgtcaccg cggcggtcgg cggcgtcctg ctcggcctgt
    20401 actacggctt cggcaaccgc ctgggcctgc gccgctgacg ccgcctcagg ggaccagccg
    20461 ccgcaaccgt ccggcggcct cctccagcac ctccgccttc ttgcagaacg cgaaccgcac
    20521 atacggcgcg cccgcgtcct tgtggtcgta gaagacggcg ttcgggatgg ccaccacccc
    20581 ggcccgctcg ggcagcgccc ggcagaaggc gaacccgtcg ctctcgccga gcggccggat
    20641 gtcggtggtg atgaagtagg tgcccgccga ggtgaacacc tcgaaccccg cctccttcag
    20701 ccccgacgcc agcaggtccc gcttggcctg catgtccgcg cggaagtcgg cgtaatagct
    20761 gtcgggcagc gcgagcgcct cggcgacggc gtactggaac ggcccggacg ccacgtacgt
    20821 caggaactgc ttcgccgagc gcaccgcggt caccagcgcg ggcggggcgg tcacccagcc
    20881 gaccttccag ccggtgaagg agtacgtctt gccggcggag gaaatagtga cggtccgctc
    20941 ccgcatcccc ggaaacgtcg ccagcggcac atgctcggcc ccgtcgaaga cgagatgctc
    21001 gtacacctcg tccgtgacga ccagcagatc ccgctccacc gccagctccg ccaccgccgc
    21061 cagctcctca cgggtgagaa cggtgccggt cgggttgtgc ggggtgttga tcagcagcag
    21121 ccgggtgcgg tcggtgaccg ccgcgcgcaa ctcgtcgagg tcgagccgga aacgcccccc
    21181 gtccggacgc agggtgaccg gcaccctgcg tgcccccgcc atggcgatgc aggccgcgta
    21241 ggagtcgtag tacggctcca gcgccaccac ctcgtcgccg ggctccagca gcgccagcag
    21301 ggccgccgcg atggcctccg tggcacccgc cgtcaccagc acctcggtgt ccgggtcgta
    21361 cgtcagcccg tacagccgct cctggtgcgc cgccaccgcc agccgcagct cgggcacccc
    21421 cggccccggc ggatactggt tcccgcgccc gtcccgcagc gcccgcaccg ccgcctcccg
    21481 cacctcctcg ggcccgtcgg tgtccggaaa accctgcccc agattgatcg acccggtccg
    21541 cagggccagc gccgacatct ccgcgaagat cgtcgtaccg aactcggcga ggcggcggtt
    21601 gagaagagga cgcacgcttg aggtcatggc ggcatcctgc gccgaagctc tggagttcct
    21661 caactctgct ttgggccggg agcggcgggg gcatcccccg ttcacgcggc ggcgaagggc
    21721 ccacgggggg tcgctttcgg gggagtcgcg aagacggaag gaggggtggg ccatggttgt
    21781 cggcttcatc ctggtcatct ttttcgtagt ggtcgcgggc ggcatcacgg tcgccgtgct
    21841 ggcggccgga cgacggcgcg tggcgcccct gcgcggcgtg cgcggcgtgc atggcggagg
    21901 gcggggcggc gggggcggca gcagccacca cacccggcac agcagcggtg acagcggtag
    21961 ctggtgggcg ggggacagcg gcggggacag cggcgggggc ggctcctcgt gtggcagcag
    22021 ctcctcgtgc ggcagcagct cctcctcctg cggcagtagc agcagctcgt gcggcagctc
    22081 ctcgtcctgc ggcggtggcg gaggatgcgg cggcgggagc agctgacgcg ggctgagcga
    22141 gcacatgtca ggggggaatg cgcggggccc gcccacgggg ggcgggtccc gccgtcgtgt
    22201 gtgcgtgctc cggcgtgcgc ccggacgaca cggcgcacac cgtggttgaa cagttgagct
    22261 gtggagcccc ccgagggatg gaaaccctcc gaagttgggt aaaaacgctg tggcggcgcc
    22321 actgttcatg attccctcta aaacaccaac gcagcccctc ggacgtcccg cggccatccc
    22381 cactgacctc gccgactggg ctgacgggcc gatctcccgg tgtcgaccgg tgcgccggac
    22441 ccaacctccc tttctttgcg tgcttgcgga gccgatccat gctcacgacc ctgaacacct
    22501 cctacaccga cacgcgcgcg gccgacctcg cctgggcgct ggggcgtgaa ccgctccccg
    22561 cactggccac gctcgacctc gaactgtccg gggcgaagct ccagttgaga ctgctcggcg
    22621 cgtcccacca ggtgctcctg gaggaggagc ggggcgactg ctcggagacc gttgcctgca
    22681 tccccggcag cagcaccccc ctcccgctgg gcgtcgccaa gcgcgtcggg gactgggagt
    22741 acgagttcgc cgcccgcgtc gaggtactgg cgccgggcca gttcgcgggc cgtgcccagg
    22801 agttgctcgc cctggtcgcc gaccacccgc acggcctggc cggagtcttc cccggcagcc
    22861 cgcacgcctt caccgcgatg ctcgcgcacc gccacgaggg ccagttgcac tggcgcacct
    22921 ggcacgccta cccgcaggac ggccagttgg tggccacccg cacccgcgtc ggggtccggg
    22981 tgccggtcgg cgcgctgagc ccgtcgggag tttgaggacc gtaggtccac acgtgtgggt
    23041 gacgaagcgt gtcggtcccg taacgtaacg tcgcagggtg attgaaccgc acgcgcccgc
    23101 cccgcccggc cccccggcac cctggggcgg cccggcgcgg ctgcccgtcc ggcccgggac
    23161 gggacgcttc ctggtcctcg cgtgcgtctt cgtctgcgcc gcctgcggac tggtctacga
    23221 actcgaactc gtcgccctcg cctcctactt gatcggcgac tccgtcaccc aggcgtccgt
    23281 cgtgctgtcc gtgatggtct tcgcgatggg cctcggctcg ctcgtcgcca aacgcctgcg
    23341 ctggcacgcc gccgcaggct tcggcgcgat cgaggcggtg ctcgccctga tcggcggcca
    23401 cagcgcgctc gccctgtacg gcgcgttcgc ctggaccggc gactggggcg gactgtgggg
    23461 cgagggcccg cgggtcctgc tggtcgcctt ctcgctcgcc atcggcctgc tgatcggcgc
    23521 cgaagtaccg ctgctgatgg agctgatcca gcgcatccgc cgccaggacg cgggcggcgc
    23581 ggtcgccgac ctgttcgccg cggactacgt cggcgcgctc gtcggcggac tcgccttccc
    23641 cttccttctg ctgcccctgc tcggccagtt gaccggcgcg ctgatcaccg gcgcggtcaa
    23701 cgccgtcgcc ggcgccgccc tggtcctcgg cctcttcggc cgcgacctca cccggcgcgg
    23761 acgcctgctg ctgatcgccg ccaacgtcac cgtcctcg
//
