LOCUS       NZ_CP104794            21029 bp    DNA     linear   CON 09-JUL-2024
DEFINITION  Streptomyces sp. FZ201 chromosome, complete genome.
ACCESSION   NZ_CP104794
VERSION     NZ_CP104794.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. FZ201
  ORGANISM  Streptomyces sp. FZ201
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8604396)
  AUTHORS   Zhang,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2022) College of Life Science and Technology,
            Jinan University, Guangzhou, Guangzhou, Guangdong 510632, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2021
            Assembly Method                   :: unicycler v. 3.14.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 235.1x
            Sequencing Technology             :: Illumina NovaSeq6000; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025402955.1-RS_2024_07_09
            Annotation Date                   :: 07/09/2024 06:54:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,562
            CDSs (total)                      :: 7,471
            Genes (coding)                    :: 7,336
            CDSs (with protein)               :: 7,336
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 55 of 135
            Pseudo Genes (incomplete)         :: 92 of 135
            Pseudo Genes (internal stop)      :: 7 of 135
            Pseudo Genes (multiple problems)  :: 18 of 135
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:45:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4194340
            Orig. end                         :: 4215369
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP104794.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zhang Fei, College of Life
            Science and Technology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21029
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="furan"
                     /region_number="13"
                     /rules="(mmyO or AvrD)"
                     /tool="antismash"
     cand_cluster    1..21029
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(mmyO or AvrD)"
                     /kind="single"
                     /product="furan"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21029
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11029](+)"
                     /cutoff="20000"
                     /detection_rule="(mmyO or AvrD)"
                     /neighbourhood="10000"
                     /product="furan"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11029
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(mmyO or AvrD)"
                     /neighbourhood="10000"
                     /product="furan"
                     /protocluster_number="1"
     misc_feature    18..31
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.91"
                     /tool="antismash"
     gene            156..1703
                     /locus_tag="N6J21_RS18740"
     CDS             156..1703
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009189493.1"
                     /locus_tag="N6J21_RS18740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_093724840.1"
                     /transl_table=11
                     /translation="MLDIPSRVRVHVETLLAAQNDMGVCDAFEQYAPVGKPDAMNAPHP
                     PKVAGIDSTVPSPAHTVAPAPVASESAESTADAERSVATAVAATGAAGLLLQDRLAGWV
                     SDLTTLHELTERLARTDSLSDALQELLRAGAALVGARRGLVVLEPADGRGPDTTVGLGL
                     GRADLGTIETVPRGAMSYGKILDGLPGGDREIAQPDLFAEDGLDPRHREVAARLGYAAS
                     YALPLSTEAAGRLGAAVWLYDEPAEPAERQRHLVGLYTSHATEHLARLLEVERTRACMA
                     TMAEELLPSRLPRVAGVQLAARHRTGPLGGGDWYDALPLPDAALGLAVGSVTGSGPSAI
                     AAMGRLRASLRAYAVMEGEDPVAVLSDLELLLRLTEPARSATALFAYCEPALRKITLAG
                     AGHCPPLLIGERRTEFVETSVSAPLGMLACWEAPSVEFQVEPGETVLLYSDGLLHRTGD
                     ATDRAFARLHTAAAGVPRSIRNDPDAVAEHVLRTVLPDGLDAADHSEDVVLLAARFE"
     misc_feature    complement(181..196)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 22.07"
                     /tool="antismash"
     misc_feature    complement(1709..1724)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.68"
                     /tool="antismash"
     gene            1801..3258
                     /locus_tag="N6J21_RS18745"
     CDS             1801..3258
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003974973.1"
                     /locus_tag="N6J21_RS18745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_093724850.1"
                     /transl_table=11
                     /translation="MSEELTPETPEESEEPIKQRKNGLYPGVSDELAENMKSGWADTEL
                     RDLEPIPQAAETAARRAALSARFPGERLVIPAGNLKTRSNDTEYPFRASVEYAYLTGNQ
                     TEDGVLVLEPVADGHEATIYLLPRSDRENGEFWLSGQGELWVGRRHSLTEAGTLYGIPA
                     SDVRELADKLREATGPVRVVRGYDAGIEAALTDKVTAERDEELRVFLSEARLVKDDFEI
                     GELQKAVDSTVRGFEDVVKVLDKAEATSERYIEGTFFLRARVEGNDVGYGSICAAGPHA
                     CTLHWVRNDGPVRSGDLLLLDAGVETHTYYTADVTRTLPINGTYTELQKKIYDAVYDAQ
                     EAGIAAVKPGAKYRDFHDAAQRVLAERLVEWGLVEGPVERVLELGLQRRWTLHGTGHML
                     GMDVHDCAAARVESYVDGTLEPGMVLTVEPGLYFQADDLTVPEEYRGIGVRIEDDILVT
                     ENGNRNLSAALPRRSDEVEAWMAGLKG"
     gene            3363..3710
                     /locus_tag="N6J21_RS18750"
     CDS             3363..3710
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N6J21_RS18750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_250748203.1"
                     /transl_table=11
                     /translation="MLSTAALLLVAVTGCVSSTDSLGEAPEVEVTDYGTRWREEKFVAE
                     AEYTIRNPYSDPVEFRVGFSFTSDGSDTLEWATRTVDAGTTVTGTVFVPWEKHLPSPRV
                     EVESVREERRS"
     misc_feature    3366..3368
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3722..5086
                     /locus_tag="N6J21_RS18755"
     CDS             3722..5086
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (110-369). E-value: 1e-22.
                     Score: 72.7. Matches aSDomain:
                     nrpspksdomains_N6J21_RS18755_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999813.1"
                     /locus_tag="N6J21_RS18755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_261718863.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.2e-20, bitscore:
                     72.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLHVELAPGEGRRDGLERALRDAVRDGRLAAGERLPATRRLAEE
                     LGVSRNTVKAAYDQLVAEGYFTARQGSGTRVAELASPGAGAVETAARVRAPKFDLRPGS
                     PDVGAFPAAAWLRALRRAVATAPSLAYDYGDPRGRIELRTALSGYLGRARGVIAPPERI
                     VVTSGYVQGLALLTRVLDEGGGFGMEDPGLPFHREVVRRNGGTVVPVPVDERGAVADGL
                     GDAAAVVVTPAHQYPTGVTLHPERRRALTDWARARGALIVEDDYDGEFRYDRQPVGALQ
                     GMAPGCVVYLGTASKTLGPALRLGWMVLPPALVDAVVDAKLHSDHHTETLGQLALAELI
                     DSHAYDRHVRACRLRYRRRRDLLVERIAGRPGVRGVRGIAAGLHALVEVDDEAEVLARA
                     RVEGLAVGALGEHWHGEGDQDRRGPVQGLVVGYGTPRERVYPEAVEVLGRVLGGA"
     aSDomain        4052..4828
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_N6J21_RS18755_Aminotran_1_2.1"
                     /evalue="1.00E-22"
                     /label="N6J21_RS18755_Aminotran_1_2.1"
                     /locus_tag="N6J21_RS18755"
                     /protein_end="369"
                     /protein_start="110"
                     /score="72.7"
                     /tool="antismash"
                     /translation="PAAAWLRALRRAVATAPSLAYDYGDPRGRIELRTALSGYLGRARG
                     VIAPPERIVVTSGYVQGLALLTRVLDEGGGFGMEDPGLPFHREVVRRNGGTVVPVPVDE
                     RGAVADGLGDAAAVVVTPAHQYPTGVTLHPERRRALTDWARARGALIVEDDYDGEFRYD
                     RQPVGALQGMAPGCVVYLGTASKTLGPALRLGWMVLPPALVDAVVDAKLHSDHHTETLG
                     QLALAELIDSHAYDRHVRACRLRYRRRRDLLVERIAG"
     misc_feature    complement(5164..5184)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.61"
                     /tool="antismash"
     gene            5175..6398
                     /locus_tag="N6J21_RS18760"
     CDS             5175..6398
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005316585.1"
                     /locus_tag="N6J21_RS18760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_261718864.1"
                     /transl_table=11
                     /translation="MTNSLVPPAGPQRVLALAQLSNSVGDGAFYVTSALYFTYVVGLDP
                     ARVGLGLTVAWAVGSLAGVPLGRLADRRGARGTAVLLALATGLSVASFLVVRGFWPFVA
                     AAVVYATAQSGLAAARQALLAGLVSAEERTGLLAHLQSTLNAGLAVGAGLGGLALHVGS
                     RGAYLGVFALDAVSFLLCAGVLSRLPSVAPVAVNRSAGASVTVLRDRPYVVVAALNAVL
                     LLRMPLLSLGLPLWVAERTAAPEWVVSVLFVLNTVAVMLFQVRMARGVTGILSAVGVLR
                     RSGWVMGAACGVFAVSGPAGSAWVAVGVLVVGAVLLVVGEMGQSAGAWQLSFDLAPGDR
                     VGEYQGFFGTGVTVARTAGPLVLTLLLVEWGPWGGAVGGGDLGGSYAMGPAARWASARR
                     EAVLVPAA"
     gene            complement(6468..7304)
                     /locus_tag="N6J21_RS18765"
     CDS             complement(6468..7304)
                     /EC_number="2.4.2.52"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134073.1"
                     /locus_tag="N6J21_RS18765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="triphosphoribosyl-dephospho-CoA synthase"
                     /protein_id="WP_261718865.1"
                     /transl_table=11
                     /translation="MTGSHEDEELARTAVTALTEQLALTSKPGLPDPSHPDHHTLRWSA
                     KALAPGLAAIAAAARRTGEPTPALRAELGAIARGTEHSVCLAGGGHRGALWTLGLLVAA
                     AAMTPADVLPTAKRLAALPDRGAPRRPSRGSTMSAKYGAQGARGEARAGFPHIRRTLPL
                     LTESPASRRDALLTIMSTLRDTELLYTAGPHGLHHVQARAADILSTGGTDTLAGARALS
                     ALNTDLHERGWTPRGSATLLTGALFVASLRRETPVAAGSRAAGAARVGAAAPGQRR"
     gene            complement(7282..8013)
                     /locus_tag="N6J21_RS18770"
     CDS             complement(7282..8013)
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011039537.1"
                     /locus_tag="N6J21_RS18770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAD family hydrolase"
                     /protein_id="WP_261718866.1"
                     /transl_table=11
                     /translation="MRRRPAAFFDVDGTVINATSMFRFLEFRLAAEGHPPSAYRHERQR
                     LKAMTAAGVPRSETNRAYFASYAGADVRAVAALAEEWFRAELDRGGFYNDQVVEALRAH
                     RRAGDLIVLVSGSFRDCLAPIARHLDADVVLCTDPETAHGRYTGRVARPMIGEAKAEAI
                     HALTDRAALDLMASTSYGDHVSDLPLLRTTGRAVVVGEDPEMREQARRHNWPLWPRLSP
                     DSQLAHSHGSYVRAHDGKPRG"
     gene            complement(8097..8549)
                     /locus_tag="N6J21_RS18775"
     CDS             complement(8097..8549)
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014664.4"
                     /locus_tag="N6J21_RS18775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_250744531.1"
                     /transl_table=11
                     /translation="MTRDIREEQRGNPRFERGHAKLLELGDNGDAIFTALADVAPDMGR
                     YVAEFVFGDLYGRGGLDDRQRQLVTLALLTALGDTERQFAFHLNLALNAGVTPQEVVDA
                     LVHGLAFVGFPRTFNGLSTAKRVFAERGLLPVADAPAADAPLAEAG"
     gene            complement(8546..9292)
                     /locus_tag="N6J21_RS18780"
     CDS             complement(8546..9292)
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015659341.1"
                     /locus_tag="N6J21_RS18780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_261718867.1"
                     /transl_table=11
                     /translation="MCHSTDSRPPAVENPGSVAEEGLIELTSQDGTTFSAFHAHPGEPN
                     GRGVVILPDIRGVHAYYQDLARRFAEAGFAAVVLDYYGRTAGLGPRDDEFEWQPHFQQL
                     VPDSVADDAAAAVAYLTGKNPGITVFSVGFCLGGGHSWRLAGTELPLAGSIGFYGLPGL
                     VEDRLKDISAPLLLLLAGDDVATTQEDFEAFRGKLDDAGKAYEYKVYDGAPHSFFDGGA
                     PEWQDISADAWQRVLDFTDRHAQAAA"
     gene            complement(9343..9786)
                     /locus_tag="N6J21_RS18785"
     CDS             complement(9343..9786)
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1144: thioesterase superfamily protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324856.1"
                     /locus_tag="N6J21_RS18785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hotdog fold thioesterase"
                     /protein_id="WP_093725037.1"
                     /transl_table=11
                     /translation="MSDSTLGPWAVTPEFSHQQLVTKMGIELVRCEAGLVIGTMPVDGN
                     RQPVGIMHGGANAVLAETLGSLAAYLYTGPGGRAVGLDLSCTHHRWVAGGTVTGVCRPL
                     HEGRTTATYEIVITDSSGRRTCTARLTCAVSVRARSRDVLRTA"
     gene            10001..11029
                     /locus_tag="N6J21_RS18790"
     CDS             10001..11029
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) furan:
                     AvrD"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017469.4"
                     /locus_tag="N6J21_RS18790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AvrD family protein"
                     /protein_id="WP_093725035.1"
                     /sec_met_domain="AvrD (E-value: 4.5e-131, bitscore: 435.9,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGTLPAKELLLDSVDDYLGPGEKRFFGSGFRRVRYRYDKAELTG
                     GPGAPTELSSRLDVVYPADWSRKATARGDLRPHLSTVDGLIIAVHLSEAALTHSLGLGP
                     ESRRAGRVLSVRIKAGTEPDEELTGLPVRTTVLGEPVRSGEGEAVSRLQTLVGAMRVRT
                     DLRHPLPTPPPGTPVATAAYTGPAELLGPVERQYYGTGFTARTQSVRKVAVRAAEARAR
                     AVVDVAQEPGTALATEGFEGLYQPFVGLIDTFVTSLQLGQILLYETDGISRGASNTLWM
                     RTTVLRASAEPDPIRYETPLDVRLENSTLLRRENETWRAADIVGRLAGNTVRCSVAHRL
                     PG"
     gene            11093..11806
                     /locus_tag="N6J21_RS18795"
     CDS             11093..11806
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015659338.1"
                     /locus_tag="N6J21_RS18795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AAA family ATPase"
                     /protein_id="WP_093725033.1"
                     /transl_table=11
                     /translation="MRIAISGTYSSGKTLTSYALAHYVGIPRTRARTMRELLPEAVPGK
                     TLEQCTAAELVQLIVRRHVDRAVHESSFEGSFISDGSSLQEWIYGSVRVIVGINPNESL
                     HLSELESVERTADIRVFDAVMEQLGIAFKQHVKQTYDVFVHLPNELALAADGHRPVNER
                     FRSMADERLLEVAAELGIPAHVVGGTVAERLVEIARLFDLPALMSPEEAIARAQAEYEA
                     LDMRTESDRASVIVR"
     gene            11803..12834
                     /locus_tag="N6J21_RS18800"
     CDS             11803..12834
                     /EC_number="2.3.1.180"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015659337.1"
                     /locus_tag="N6J21_RS18800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="WP_093725031.1"
                     /sec_met_domain="fabH (E-value: 8.7e-114, bitscore: 378.7,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPTAVLAGLGSAVPPRVVTNDELTARMDTSDEWIRTRTGIAER
                     RIVDPGTATSDLAIEAGRRALDSAGSRDIGAVVVATATPDHPCPATGPTVAAGLGLGTV
                     PAFDVGAVCSGFLYALATGAGLIASRVVDSVLVVGADAFTTIVDPYDRNTAPIFADGAG
                     AVVLRAGRADEPGALRRTELASDGLQADLIRVAAGGSRQRSHHNTALREDHYLTMRGGE
                     VFKNAVLRMTEASRTVLERTGWSTADVDLFVGHQANVRILHAVADQLGIGQERAYVNIG
                     HTGNTAAASIPLALDDALGEGRLRAGDKVLLTAFGAGTTWGAITLTWPDGLRPADAPHP
                     AAA"
     gene            12919..13158
                     /locus_tag="N6J21_RS18805"
     CDS             12919..13158
                     /NRPS_PKS="Domain: PP-binding (7-73). E-value: 5.7e-15.
                     Score: 47.4. Matches aSDomain:
                     nrpspksdomains_N6J21_RS18805_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="N6J21_RS18805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl carrier protein"
                     /protein_id="WP_093725029.1"
                     /sec_met_domain="PP-binding (E-value: 2.2e-11, bitscore:
                     42.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVTAYPQLVAFIAEKAEIEVEEIDPERTLEDLSLDSLTLIEIAL
                     FIQREYGIEVPEGDLVLSQKLAEWTAYLDERSGR"
     aSDomain        12940..13137
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_N6J21_RS18805_PP-binding.1"
                     /evalue="5.70E-15"
                     /label="N6J21_RS18805_PP-binding.1"
                     /locus_tag="N6J21_RS18805"
                     /protein_end="73"
                     /protein_start="7"
                     /score="47.4"
                     /tool="antismash"
                     /translation="QLVAFIAEKAEIEVEEIDPERTLEDLSLDSLTLIEIALFIQREYG
                     IEVPEGDLVLSQKLAEWTAYL"
     gene            13155..14099
                     /locus_tag="N6J21_RS18810"
     CDS             13155..14099
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (15-312). E-value: 7.2e-47.
                     Score: 151.9. Matches aSDomain:
                     nrpspksdomains_N6J21_RS18810_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979474.1"
                     /locus_tag="N6J21_RS18810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_250744528.1"
                     /sec_met_domain="ADH_N (E-value: 8.9e-06, bitscore: 24.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.7e-11, bitscore:
                     43.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTMKAVVTTAVGEPDVLRLTGVERPAPLPTEVLVRVEGAGVNPV
                     DWKIRSGLFPSGALGAPPFVQGWDVAGVVESGPRVTRFEPGDEVFGLIGFPRPGGAYAE
                     YVTAPARQFARKPTRLSFEEAAALPLAGLTGWQTLVETARIQRGDKVLVTAAAGGVGHL
                     AAQIARAHDAEVTGTARAEKHDFLREVGVDHPVDYRTGPLHHTVTGQDVVLDLLGGEHS
                     FELLRTLRPGGLLITVIGHVSPELATYAASLGVRVTGFLVEPDHSGLEALAALVEAGRL
                     KVRVDQVFKLAEAAKAHEYGESDRTTGKIVLVP"
     aSDomain        13200..14090
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_N6J21_RS18810_PKS_ER.1"
                     /evalue="7.20E-47"
                     /label="N6J21_RS18810_PKS_ER.1"
                     /locus_tag="N6J21_RS18810"
                     /protein_end="312"
                     /protein_start="15"
                     /score="151.9"
                     /tool="antismash"
                     /translation="DVLRLTGVERPAPLPTEVLVRVEGAGVNPVDWKIRSGLFPSGALG
                     APPFVQGWDVAGVVESGPRVTRFEPGDEVFGLIGFPRPGGAYAEYVTAPARQFARKPTR
                     LSFEEAAALPLAGLTGWQTLVETARIQRGDKVLVTAAAGGVGHLAAQIARAHDAEVTGT
                     ARAEKHDFLREVGVDHPVDYRTGPLHHTVTGQDVVLDLLGGEHSFELLRTLRPGGLLIT
                     VIGHVSPELATYAASLGVRVTGFLVEPDHSGLEALAALVEAGRLKVRVDQVFKLAEAAK
                     AHEYGESDRTTGKIVL"
     CDS_motif       13596..13658
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_N6J21_RS18810_0001"
                     /evalue="6.50E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="N6J21_RS18810"
                     /protein_end="168"
                     /protein_start="147"
                     /score="15.6"
                     /tool="antismash"
                     /translation="GDKVLVTAAAGGVGHLAAQIA"
     gene            14096..15427
                     /locus_tag="N6J21_RS18815"
     CDS             14096..15427
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016577260.1"
                     /locus_tag="N6J21_RS18815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_261718868.1"
                     /transl_table=11
                     /translation="MTSPFAANGPAGRLLARIRPAVQVRRKERQRTAAPHDGEGGVPAP
                     ATAAAGTLRPGGGLPDRLVTVLAVAAGLAVANIYYAHPLLTSIAASFGVGSTAASLVVT
                     ASTAGYTVGLALLVPLGDTVNRRRLLVALLLVTALGQAASAAAPGIGALVVLSGLMAVT
                     AVGAPLLVAFAAALARPEQRGRVTGRMLSGVLLGVLLARTGAGLLAEWTGTWRSVFAVA
                     AAGMLVLAALLWRLLPDLEPAERLGYGRLLRSVASVVAEEPLLRLRCLYGFLTFASFSV
                     FWTSAAFLLAEEPYAYGEALIGAFGLLGAAGAIAARAIGPLVDRGRDRLASTLLYGANL
                     AAWGLLALDGGHLLVCLVLGVLLLDFGVQGAQVTNLGVLYRLRPEARSRITMAYMTAYF
                     LGGAAGSALSGAVHSAAGWAGVCAAGGGLAALVLLLWGLEQARA"
     gene            15482..17050
                     /locus_tag="N6J21_RS18820"
     CDS             15482..17050
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="N6J21_RS18820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_261718869.1"
                     /transl_table=11
                     /translation="MSTASTGAARSRPLLTLIAVCVSCGLLPASLTGTSVALPDLGSDL
                     DASLVTVQWVVNAYNLTFASVMLVAGSLADLLGRRRMFTAGLVVFVLCTAGSALVSEVV
                     VIDVLRGAAGVGAAMVLTAATALLAQSYDGAARARAFGFLGSSFGLGLALGPSLSGFLV
                     GAWGWRSVFLAHAAVAAAVLLLRPALKESRDPEAAGVDYGGATTFSGALFSFTLALVEG
                     PQLGWTHPAVLALAVLSVALMAAFVRIEKRRARPMLELSLLREPKFAAVSLMPVLLAFG
                     FVCLLVFLPSFFIGVNGMSSSRAGLTMLLLSGPVLALPVVSGVLTRRVSTSVLLGVSLL
                     LVAGGAAWLTVLDQDATTAVLAGPLLVIGTGVGISFGLLDGAAVGSVDASRAGMAAGLF
                     NTMRLTGEAVAIAGMGSVLVSLTQSNLRGWSGGDVDGLANQVVQGEIGAAADELPAAQQ
                     ADFTAFAADAYTDALHTVLWLLAAVCALGAPLIMRMLRPAPAAEAPAAADRDDTREPIT
                     MGETS"
     gene            17047..18555
                     /locus_tag="N6J21_RS18825"
     CDS             17047..18555
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="N6J21_RS18825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_261718870.1"
                     /transl_table=11
                     /translation="MSTPDTRPVLVVGAGPVGLTAAAELARRGTPVRLIDRTDAPSPLT
                     KALMVWPRTLEVFRGLGADGYIDKHGLPVHSFRYNSGTDPICDIVFGDRTRPMVIIQPD
                     VEELLREAFTRAGGRIEWETELTRLSQDPDGVLATLRAPDGTETTEEYAYVVGGDGASS
                     TVRKALGIEFKGATYPNVFILADTEIDGDLQRDAVHYYCTENGIMVLIPLYNGRFRVFT
                     AGPPGLRGEDLTEELLQDFVDKRGPGGLKLYDVSWKTTFAIHARHAERFRAGRVFLAGD
                     AAHIHSPAGGQGLNTGVTDAHNLAWKLALVHRGAAAPELLDSYGSERAAVAQGVVKQAE
                     VQTKAWMLSKRWQIQLRDVSARMAERSGVFDRFYSPWLAGLTNHYPAGPAVDEEQGRRL
                     RRTGPRNGHLVADAALRASLPVDRYTLLVTLPSGPRPPRLAEVEKSYDELVTVRTKPGR
                     RFSAVLVRPDHYVAAQDHAPELTRVLGHLATLAPAALIEEGHSA"
     gene            18552..18965
                     /locus_tag="N6J21_RS18830"
     CDS             18552..18965
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024092.4"
                     /locus_tag="N6J21_RS18830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_261718871.1"
                     /transl_table=11
                     /translation="MTQQQVRGTADTVQEFFGRFGTGDLAGLAELFAEEAELVVAGAPI
                     VPWTGRLVGRREVEGYFERFVAAVDTQLFDVERIAVDGEDAFVLGEFSHKVVSTGKTFS
                     GPFTIRITVRDGLIQRYQTFEDSYAAAMAFGSD"
     gene            complement(18932..19849)
                     /locus_tag="N6J21_RS18835"
     CDS             complement(18932..19849)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037627.4"
                     /locus_tag="N6J21_RS18835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_093725019.1"
                     /transl_table=11
                     /translation="MTIGRRKRQLEELSHFLRTRRMRLSPAEVGLTASGRRRTPGLRRE
                     EVAVLAGVGTSWYTWLEQGRDINVSESVLGAISGALRLNPAEEIYLHRLAGLKTPDVDQ
                     RENSGPADPARLAEIVNHWFPNPALVRDRCWNILAANSAVSEFLGIGGPGQNILVEYFT
                     NEACRRRYVHSEALARSTVARFRADVADCYGRPEVERVLAELTERSPEFKRLWGSHEVL
                     EPSPSRAKEITHDTVGGLSFDVHEWELAADHEVQLVLHMPTVQETRDRLDAFFAAAGPD
                     EPDRPGEDTAGDDGQSEPKAIAAA"
     misc_feature    19912..19923
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.37"
                     /tool="antismash"
     gene            complement(20112..20564)
                     /locus_tag="N6J21_RS18840"
     CDS             complement(20112..20564)
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388894.1"
                     /locus_tag="N6J21_RS18840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_093725017.1"
                     /transl_table=11
                     /translation="MSIWWSLHLRREAASVPLARRLLLGTMESAGVDPDISYDLSVALS
                     EACANAVEHGGDGALDGAAEAYRVTAYLDGETCRIEVADSGPGFGAAGGDAGRLSAEAE
                     NGRGLYLIQELADHVHFGTEPGLGGAVVSFDKILKWRKGASPLLAV"
     misc_feature    20622..20639
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.53"
                     /tool="antismash"
     misc_feature    complement(20904..20922)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.83"
                     /tool="antismash"
ORIGIN
        1 tacccatcac gaccgctgtg acgctccgtg gagcaaggcc agtcgaccgc aataacgcgt
       61 tcactgaggc agttttaagc caactttgcc tttccgcaag gggttgggga gatgtccact
      121 caggacccat ggacaccagg aatcccagca ggacaatgct ggacatcccc tcacgagtgc
      181 gtgtacatgt ggagacactg ctagcggcgc agaatgacat gggggtttgc gatgcttttg
      241 agcaatacgc accggtcgga aagccggacg ccatgaacgc ccctcaccct ccgaaagtgg
      301 ccggaatcga ttcaacggtt ccctcgcccg cacacactgt cgcgcccgcg cccgtggcat
      361 cggaaagcgc agaaagcaca gcagacgcag aacgctccgt cgccaccgcc gtcgccgcga
      421 ccggcgccgc cggactcctc ctccaggacc gtctcgccgg ctgggtctcc gacctcacca
      481 ccctgcacga actgaccgag cgactggcgc gaaccgactc cctctccgac gccctccagg
      541 aactgctccg cgccggagcc gccctcgtcg gcgcccggcg cggactcgtc gtcctggagc
      601 ccgccgacgg acggggcccg gacaccaccg tcggcctcgg cctcggccgc gccgacctcg
      661 gcaccatcga gaccgtgccg cgcggcgcca tgtcgtacgg gaagatcctc gacgggctgc
      721 ccggcgggga cagggagatc gcccagcccg acctgttcgc cgaggacggc ctcgaccccc
      781 ggcaccgcga ggtggccgcc cgcctcggct acgccgcgag ctacgccctc cccctgagca
      841 ccgaggccgc cggccggctc ggcgccgccg tgtggctcta cgacgagccc gccgaacccg
      901 ccgagcggca gcggcacctc gtcggcctct acaccagcca cgccaccgag cacctggccc
      961 ggctgctgga agtggagcgc acgcgcgcgt gcatggcgac gatggcggag gaactgctgc
     1021 cgtcccggct gccccgggtg gccggggtcc agctcgccgc ccggcaccgc accggcccgc
     1081 tcggcggcgg cgactggtac gacgcgctgc cgctgcccga cgccgccctc gggctcgccg
     1141 tgggctcggt caccggctcg gggccgagcg cgatcgccgc gatggggcga ctgcgcgcct
     1201 cgctcagggc gtacgcggtg atggagggcg aggacccggt cgcggtcctg tccgacctgg
     1261 aactgctgct gcgtctcacc gagcccgccc gctccgccac cgccctgttc gcctactgcg
     1321 aacccgcgct gcgcaagatc accctcgccg gggccgggca ctgcccgccg ctgctgatcg
     1381 gcgagcgccg caccgagttc gtggagacct ccgtctccgc cccgctcggc atgctggcct
     1441 gctgggaggc gcccagcgtg gagttccagg tggagcccgg agagacggtt ctgctctact
     1501 ccgacgggct gctgcaccgt accggcgacg ccacggaccg ggccttcgcc cggctgcaca
     1561 ccgcggcggc cggagtaccc cgctcgatcc gcaacgaccc ggacgccgtc gccgagcacg
     1621 tcctgcgcac ggtgctcccc gacggcctgg acgcggcgga ccactccgag gacgtggtgc
     1681 tgctcgcggc ccgcttcgag taggagtacg tgagcccggt aacaggtcct tcgcccctgg
     1741 gcccccttcc tcgcgaccgt acgatggagg gggtccagtg ccgtatctag gaggatgacc
     1801 gtgtcggaag aactcacgcc ggagaccccg gaagagtccg aagagccgat caagcagcgc
     1861 aagaacggcc tgtacccggg cgtctccgac gagctggccg agaacatgaa gtccggctgg
     1921 gccgacaccg agctgcgcga cctggagccg atcccccagg ccgccgagac cgccgcccgg
     1981 cgcgccgcgc tctccgcccg cttccccggt gagcgtctgg tgatccccgc gggcaatctg
     2041 aagacccgct ccaacgacac ggagtacccc ttccgcgcgt cggtggagta cgcctacctc
     2101 accggcaacc agaccgagga cggcgtcctg gtcctggagc ccgtggccga cggtcacgag
     2161 gccacgatct acctgctgcc gcgctccgac cgggagaacg gcgagttctg gctctccggc
     2221 cagggcgagc tgtgggtcgg ccgccggcac tccctcaccg aggccgggac gctgtacggc
     2281 atccccgcct ccgacgtgcg cgagctggcg gacaagctgc gcgaggccac cggcccggtc
     2341 cgcgtcgtac gcggctacga cgccgggatc gaggccgcgc tgaccgacaa ggtcaccgcc
     2401 gagcgggacg aggagctgcg ggtcttcctc tccgaggcgc ggctggtgaa ggacgacttc
     2461 gagatcggcg agctgcagaa ggccgtcgac tccaccgtgc gcggcttcga ggacgtggtg
     2521 aaggtcctcg acaaggccga ggcgacctcg gagcgctaca tcgagggcac gttcttcctc
     2581 cgcgcccgcg tcgagggcaa cgacgtcggc tacggctcca tctgcgcggc cggtccgcac
     2641 gcctgcaccc tgcactgggt gcgcaacgac ggcccggtgc gctccggcga cctgctgctg
     2701 ctggacgcgg gcgtggagac gcacacgtac tacacggccg acgtcacccg caccctgccg
     2761 atcaacggca cgtacaccga gctgcagaag aagatctacg acgcggtgta cgacgcccag
     2821 gaggccggta tcgcggccgt gaagccgggc gcgaagtacc gggacttcca cgacgccgcc
     2881 cagcgggtgc tcgccgagcg gctggtggag tggggtctgg tcgagggtcc cgtggagcgg
     2941 gtccttgagc tgggcctcca gcgccgctgg acgctgcacg gcacgggcca catgctcggc
     3001 atggacgtcc acgactgcgc tgccgcgcgg gtcgagtcgt acgtcgacgg cacgctggag
     3061 ccgggcatgg tcctcacggt cgagcccggc ctgtacttcc aggccgacga cctcaccgtc
     3121 ccggaggagt accgcggcat cggcgtccgg atcgaggacg acatcctcgt cacggagaac
     3181 ggcaaccgga acctgtcggc ggcgctgccg cggcggtcgg acgaggtcga ggcttggatg
     3241 gcggggctga agggctgacg gtccgccccg tgggatgact cgatgtacac cctcggtacg
     3301 gagaaatgct tggtgtgttc gaggggcgcg ctctagcgtg ccgcaccatg cgaccacgat
     3361 ccgtgttatc cactgccgca cttctcctcg tcgccgtcac cggctgcgtc agctccaccg
     3421 actcgctcgg cgaagcaccg gaggtggagg tgaccgacta cggcacccgc tggcgcgagg
     3481 agaagttcgt ggcggaagcg gagtacacca ttcgcaaccc ctactccgac ccggtcgagt
     3541 tccgggtcgg gttcagcttc accagcgacg gcagcgacac ccttgagtgg gccacgcgca
     3601 cggtggatgc cgggacgacg gtcaccggaa cggtgttcgt gccgtgggag aagcaccttc
     3661 cgtccccgcg ggtcgaggtg gagtcggtac gcgaggaacg gcgctcttag cggggagttc
     3721 tgtggacctg cacgtggagc tcgcccccgg tgaggggcgg cgggacgggc tggagcgggc
     3781 tctgcgggat gccgtgcggg acgggcggct ggcggccggg gaacggttgc ctgcgacgcg
     3841 gcggctcgcg gaggagctgg gggtttcgcg gaacaccgtg aaggcggcgt acgaccagct
     3901 cgtcgccgag gggtacttca ccgcgcggca ggggtccggg acgcgggttg ccgagcttgc
     3961 ctcccccggt gctggggcgg tggagacagc ggcacgcgtg cgtgcgccga agttcgatct
     4021 gcggccgggg agtcccgatg tgggggcgtt tccggcggcg gcctggctgc gggcgttgcg
     4081 gcgggccgtg gcgacagcgc cgtccctcgc atacgactac ggcgatccgc ggggacggat
     4141 cgaactgcgg accgcgctgt ccgggtatct ggggcgggcg cgaggcgtca tcgcgccgcc
     4201 cgagcggatc gtggtcacct ccgggtacgt gcaggggctg gcgttgctca cgcgggtgct
     4261 cgacgagggc ggggggttcg ggatggagga tcccgggctg ccctttcatc gggaggtcgt
     4321 gcggcgcaat ggcgggactg tcgtgccggt gccggtggac gagcgcgggg ccgtggcgga
     4381 cgggctcggg gacgcggcgg cggtcgtcgt gacgcccgcg catcagtacc cgaccggggt
     4441 caccctccat ccggaacggc ggcgggcgct caccgactgg gcacgcgcgc gtggcgcgct
     4501 gatcgtcgag gacgactacg acggggagtt ccggtacgac cggcagcccg tgggggcgct
     4561 gcaagggatg gcgccggggt gcgtggtgta tctcgggacc gcctccaaga cgctcgggcc
     4621 cgcgttgcgg ctcgggtgga tggtgctgcc gcccgccctt gtggacgcgg tcgtcgacgc
     4681 caagctgcac agcgatcatc acaccgagac cctggggcag ttggcactcg ccgagctgat
     4741 cgacagccat gcctacgacc gtcatgtgcg ggcctgccgg ttgcggtacc gcaggcggcg
     4801 ggacctgctc gtggagcgga tcgcggggcg gccgggagtg cgcggggtgc ggggcatcgc
     4861 ggccgggctg cacgcgctgg tggaggtcga cgacgaggcg gaggtgctgg cgcgggcgcg
     4921 ggtggaaggg cttgcggtgg gagcgctggg ggagcactgg catggggagg gggaccagga
     4981 ccgccggggg ccggttcagg ggctggtcgt ggggtacggg acgcctcggg agcgggtgta
     5041 tccggaggcg gtggaggtgt tggggagggt gttgggcggg gcgtaggggg ccgggcggcg
     5101 ggcgtaattg ggccaaggtt ttcggttgtt agtggtcctg tttacgggtc cagttggttc
     5161 ctagtgtcgt ctgtatgacg aactcactcg ttccgcccgc gggtccgcaa cgcgtcctgg
     5221 cgctggccca gttgtccaac tcggtcggtg acggtgcctt ctatgtcacc tcggcgctgt
     5281 acttcaccta cgtcgtcggg ctcgaccccg cgcgggtcgg gctcgggctg accgtcgcgt
     5341 gggcggtcgg gtcgctggcg ggggtgccgc tggggcggct cgcggaccgg cgtggggcgc
     5401 gggggacggc ggtgctgctc gcgctcgcga ccgggctgtc ggtggcgtcc ttccttgtcg
     5461 tgcgggggtt ctggccgttc gtggcggccg ccgtcgtcta tgccaccgcg cagtccgggc
     5521 tggcggcggc tcggcaggcc ctgctggcgg ggctggtgtc cgccgaggag cggaccgggt
     5581 tgctggcaca tctgcagtcc acgctgaacg cggggctcgc ggtgggggcg gggctgggtg
     5641 ggctggcgct gcatgtgggg tcgcggggcg cgtatctcgg ggtgttcgcg ttggacgcgg
     5701 tgagttttct gctgtgcgcg ggggtgttgt cgcggttgcc ctcggtggcg ccggtggccg
     5761 tgaatcgttc cgctggggcg tccgtgacgg tgctgcggga tcggccgtat gtggtcgtgg
     5821 ccgcgttgaa cgccgtgctg ctgctgcgga tgccgttgtt gagtctgggg ttgccgctgt
     5881 gggttgccga gcggacggcg gcgccggagt gggtggtgtc cgtgctgttc gtgctcaaca
     5941 ccgttgccgt gatgctgttt caggtgcgga tggctcgggg ggtgaccggg atcctgtccg
     6001 cggtgggggt gttgcggcgg tcggggtggg tgatgggcgc ggcgtgcggg gtgttcgcgg
     6061 tgtcggggcc cgctgggtcg gcgtgggttg cggtgggggt gctggtggtg ggggctgtgc
     6121 tgcttgtcgt gggggagatg gggcagtcgg cgggggcttg gcagttgtcg ttcgatctgg
     6181 cgccggggga tcgggtcggg gagtaccaag ggttcttcgg gacgggggtg actgtggcgc
     6241 ggactgcggg gccgctggtg ctgacgttgc tgttggtgga gtgggggcct tggggtgggg
     6301 ctgttggggg cggcgacctt gggggctcgt atgcgatggg gccggcggcg cggtgggctt
     6361 cggcgcggcg ggaggcggtc ctggtgccgg ctgcgtgacc ggtgcgctgg gctggggcgg
     6421 ggggtgcgct tacgggtgcc ctgggctggg gcgggcgggg ggtgcgctca ccggcgctgg
     6481 ccgggtgccg ctgcgcccac ccgtgccgcc ccagcggcac gactgcccgc agctacgggg
     6541 gtttcgcggc gcagcgacgc tacgaacagt gcccccgtca gtagtgtcgc gctccccctc
     6601 ggggtccagc cccgttcgtg taggtccgtg ttcagggctg acagggccct ggctcccgca
     6661 agggtgtccg tgccgcccgt cgacaggatg tcggccgcgc gggcctggac gtggtggagg
     6721 ccgtgggggc ctgcggtgta caggagttct gtgtcgcgga gggtggacat gatggtgagg
     6781 agggcgtctc ggcgggaggc gggggactcc gtgaggagcg ggagtgttct gcggatgtgc
     6841 gggaagcccg cgcgggcctc gccgcgggcg ccctgggcgc cgtacttggc ggacatcgtg
     6901 gagccccggg acgggcggcg cggggcgcct cggtcgggga gggcggcaag gcgcttcgcc
     6961 gtcggcagta cgtcggccgg ggtcatcgcc gccgcggcca ccagcaggcc cagcgtccac
     7021 agcgcgcccc ggtgtccgcc gcccgcaaga caaacggagt gctccgtgcc gcgggctatc
     7081 gcgccgagtt ccgcgcgcag ggcgggggtc ggctcgccgg tgcggcgggc cgccgccgcg
     7141 atggccgcga ggccgggggc cagggccttc gccgaccagc gcagggtgtg gtggtccggg
     7201 tgggaggggt cgggcaggcc cggtttcgac gtcagggcca gttgttccgt cagcgcggtc
     7261 accgccgtcc gcgccagctc ctcatcctcg tggcttcccg tcatgggccc gaacgtagga
     7321 cccgtggctg tgcgcgagct gggagtcggg tgagagacgc ggccacaggg gccagttgtg
     7381 gcggcgggcc tgttcgcgca tttccgggtc ctcgcccacc acgaccgccc ggcccgtcgt
     7441 acggagcagg ggcaggtcgg agacgtggtc gccgtaggac gtggaggcca tgaggtccag
     7501 ggcggcccgg tcggtcaggg cgtggatcgc ctccgccttc gcctcgccga tcatcgggcg
     7561 ggccacccgg cccgtgtacc ggccgtgtgc cgtctccggg tccgtgcaca ggaccacgtc
     7621 cgcgtcgagg tggcgggcga tcggggccag gcagtcccgg aaggaacccg agaccaggac
     7681 gatcaggtcc ccggcccgtc ggtgggcgcg cagggcctcc accacctggt cgttgtagaa
     7741 gccgccccgg tccagttccg cccggaacca ttcctccgcc agcgcggcga cggcccgtac
     7801 gtccgctccc gcgtacgagg cgaagtacgc gcggttcgtc tccgagcgcg gcacccccgc
     7861 cgcggtcatc gccttgaggc gctggcgttc gtggcggtac gccgacggcg ggtggccctc
     7921 ggcggccagg cggaactcca ggaagcggaa catgctggtg gcgttgatga cggtgccgtc
     7981 gacgtcgaag aacgcggccg ggcggcggcg catggcgggt ccctcctggg gcgtgggaaa
     8041 ggggcccgcc ccgcgcgtgc ccgacggggg gtgggggcgc gcacggggcg ggagtgtcag
     8101 ccggcctcgg cgagcggggc gtcggccgcc ggggcgtccg ccaccggcag caggccgcgc
     8161 tcggcgaaga cccgcttggc cgtgctgagg ccgttgaagg tgcgcgggaa gccgacgaag
     8221 gccaggccgt gcaccagggc gtccaccacc tcctgcgggg tgacgcccgc gttcagggcc
     8281 aggttcagat ggaaggcgaa ctgccgctcg gtgtccccga gcgcggtgag cagcgccagc
     8341 gtgaccaact gccgctgccg gtcgtccagt ccgcccctgc cgtacaggtc gccgaagacg
     8401 aactcggcga cgtagcggcc catgtcgggg gccacgtcgg cgagggcggt gaagatcgcg
     8461 tcaccgttgt cgccgagttc cagcagcttg gcgtggccgc gctcgaagcg ggggttgccg
     8521 cgctgctcct cacggatgtc gcgggtcatg cggcggcctg cgcgtgccgg tcggtgaagt
     8581 ccagcacccg ctgccaggcg tcggcgctga tgtcctgcca ctccggggcg ccgccgtcga
     8641 agaaggagtg cggggcgccg tcgtagacct tgtactcgta ggccttgccc gcgtcgtcca
     8701 gcttgccgcg gaacgcctcg aagtcctcct gggtggtggc gacgtcgtcg ccggcgagga
     8761 ggagcagcag cggcgcggag atgtccttca ggcggtcctc gacgagtccg gggaggccgt
     8821 agaagccgat ggagcccgcg aggggcagct cggtgcccgc gagccgccag gagtggccgc
     8881 cgcccaggca gaagccgacg gagaagacgg tgatgccggg gttcttcccg gtgaggtacg
     8941 cgaccgcggc ggccgcgtcg tcggccacgc tgtccgggac gagctgctgg aagtggggct
     9001 gccactcgaa ctcgtcgtcg cgcggcccga gtccggcggt gcggccgtag tagtcgagga
     9061 ccacggcggc gaacccggcc tcggcgaacc ggcgggccag gtcctggtag taggcgtgga
     9121 ccccgcggat gtccggcagg atcaccacgc cgcgtccgtt gggctcaccc ggatgcgcgt
     9181 ggaaggcgct gaacgtcgtc ccgtcctggg aggtcagctc gatcagcccc tcctcggcca
     9241 cgctgccggg gttctcgacg gcggggggcc tgctgtcggt gctgtggcac atggggtgtt
     9301 ggcctctctt cgatggtgat tgcgggggga gttccgggtc cctcacgccg tgcgcaggac
     9361 gtcgcgcgag cgggcgcgga cgctgacggc gcaggtcagc cgggcggtgc aggtgcgtcg
     9421 gccggaactg tcggtgatga cgatctcgta ggtggcggtg gtgcggccct cgtgcagggg
     9481 ccggcacact ccggtcaccg tgccgccggc cacccagcgg tggtgggtgc aggacaggtc
     9541 caggccgacg gcgcggccgc cgggtccggt gtacaggtac gcggctaggg atcccagggt
     9601 ctcggccagg acggcgttgg cgccgccgtg catgatgccg acgggctggc ggttgccgtc
     9661 cacgggcatg gtgccgatga ccaggcccgc ttcgcagcgc accagctcga tgcccatctt
     9721 cgtgacgagc tgctgatggc tgaactccgg tgtcacggcc caggggccga gcgtgctgtc
     9781 ggacatggtt gcctcccccg tgtgcggcac tggaatccgt gtccgcgaac accgtcgacg
     9841 ctagtcaatt cccgggcgga cggaaaagag cggcagctgg tggtgtccag ggtggtgttg
     9901 gcagtaaccg catgagccga ctctcgttgc gccgaaatat ttcggctagc gtcgggccgt
     9961 ccgaaaaacc ccagtggccc cgacgcaagg gagttaaact ttgtctggaa ctctgcctgc
    10021 caaggaattg ctcctcgact cggtcgacga ctatctgggg ccgggcgaaa agcgattctt
    10081 cggttccgga ttccggcgcg tgcgataccg ctacgacaag gccgagctga ccggcggccc
    10141 gggcgcgccc accgaactga gcagccggct cgatgtcgtc taccccgccg actggtcgcg
    10201 caaggcgacg gcgcgcggcg atctgcgtcc gcacctgagc accgtcgacg ggctgatcat
    10261 cgccgtgcac ctgagcgagg cggcgctgac ccactcgctc gggctggggc cggagagccg
    10321 gcgcgcgggc cgggtgctgt cggtgcggat caaggcgggc accgagccgg acgaggagct
    10381 gaccggcctg ccggtgcgca ccacggtgct cggcgagccg gtccggagcg gcgagggcga
    10441 ggcggtgtcg cggctgcaga ccctggtggg agccatgcgg gtccgcaccg acctgcgcca
    10501 tccgctgccc accccaccgc ccggcacccc ggtcgccacc gccgcttaca ccggtccggc
    10561 ggagctgctc gggccggtgg agcggcagta ctacggcacc gggttcactg cccgcacgca
    10621 gagcgtgcgc aaggtcgcgg tgcgggccgc cgaggcgcgg gcgcgggccg tggtggacgt
    10681 ggcgcaggag cccggcaccg ccctggccac cgagggcttc gagggcctgt accagccctt
    10741 cgtcgggctg atcgacacct tcgtcaccag ccttcagctc ggtcagatcc tgctgtacga
    10801 gaccgacggg atctcccgcg gcgcgagcaa cacgctgtgg atgcgcacca ccgtcctcag
    10861 ggcgagtgcc gaacccgatc ccatccgcta cgaaaccccg ctcgacgtgc ggctggagaa
    10921 cagcacgctg ctgcggcggg agaacgagac ctggcgggcc gccgacattg tcggacggct
    10981 cgccggaaac accgtgcgct gttccgtggc gcaccggctg cccggctgat tcccgaccgt
    11041 ctctttcaag ggctccaaaa tcggccaccc ctttaagaaa ctggagcgcg tcatgcgtat
    11101 cgccatatcc ggtacctatt cctccggaaa aaccctcacg tcctatgcgc tcgcgcatta
    11161 cgtgggaatt ccgcgcaccc gggcccgcac catgcgcgag ctgctgcccg aggccgttcc
    11221 gggcaagacc ctggagcagt gcaccgcggc cgagctggtc cagctgatcg tccgccgcca
    11281 tgtggaccgg gcggtccacg agagcagctt cgagggctcg ttcatctccg acggctcctc
    11341 gctgcaggag tggatctacg gttccgtccg cgtcatcgtc ggcatcaacc ccaacgagtc
    11401 gctgcacctg agcgagctgg agagcgtcga acgcaccgcg gacatccggg tgttcgacgc
    11461 cgtcatggag cagctcggca tcgccttcaa gcagcacgtg aagcagacgt acgacgtgtt
    11521 cgtgcacctg cccaacgagc tggcgctggc tgccgacggg caccgcccgg tcaacgagcg
    11581 gttccgttcc atggccgacg agcggctgct ggaggtcgcc gccgaactcg gcatccccgc
    11641 gcacgtggtg ggcggcaccg tcgccgagcg gctggtggag atcgcccggc tgttcgacct
    11701 gccggcgctg atgtcgccgg aggaggccat cgcccgcgcc caggccgagt acgaggcgct
    11761 ggacatgcgc accgagtccg accgggcctc ggtgatcgtg cgatgaccgc gccgaccgcc
    11821 gttctggccg gtctcggctc cgcggtgccg ccccgggtgg tgaccaacga cgagctgacg
    11881 gcccggatgg acacctccga cgagtggatc cgcacccgga ccggaatcgc cgagcggcgg
    11941 atcgtcgacc ccggcaccgc caccagcgac ctcgccatcg aggccggacg gcgggccctg
    12001 gactccgcgg gcagccggga catcggtgcc gtggtggtcg ccaccgccac tccggaccac
    12061 ccctgcccgg cgaccggtcc gaccgtggcc gccggactcg ggctcggcac cgtgcccgcc
    12121 ttcgacgtcg gcgccgtctg ctcggggttc ctgtacgccc tggccaccgg cgccgggctg
    12181 atcgcctccc gggtggtgga cagcgtgctg gtcgtcggcg ccgatgcctt caccaccatc
    12241 gtcgacccct acgaccgcaa caccgcgccg atcttcgcgg acggtgccgg agcggtggtg
    12301 ctgcgcgcgg gccgggccga cgagccgggc gcgctgcgcc gtaccgaact ggccagcgac
    12361 ggcctgcagg ccgatctgat ccgggtcgcc gccgggggtt cacggcagcg cagccaccac
    12421 aacacggcac tgcgcgagga ccactacctg accatgcgcg gcggcgaggt gttcaagaac
    12481 gccgtcctgc gcatgacgga ggcctcccgc acggtcctgg agcgcaccgg ctggtccacc
    12541 gccgacgtgg acctgttcgt cggccaccag gccaacgtcc gcatcctgca cgccgtcgcc
    12601 gaccagctcg gcatcggaca ggagcgggcc tacgtgaaca tcggccacac cgggaacacg
    12661 gccgcggcct cgatcccgct ggccctggac gacgcgctcg gcgaagggcg gctgcgggcc
    12721 ggggacaagg tgctcctgac cgccttcggc gccggcacga cctggggcgc catcaccctg
    12781 acctggcccg acggactgcg gcccgccgac gcgccgcacc ccgccgccgc ctgatccgac
    12841 cggcgcccgc acacctcacc cccgcctcac cgaatccacg caacgccccg gagcacggct
    12901 ccgaggaggg agtaagagat gcccgtcacg gcatatcccc aactggtcgc gttcatagcc
    12961 gagaaggccg agatcgaggt cgaggagatc gacccggagc ggaccctgga ggacctctcg
    13021 ctggactcgc tcaccctgat cgagatcgcc ctgttcatcc agcgggagta cggcatcgag
    13081 gtgcccgagg gcgacctggt cctcagccag aagctggccg agtggaccgc ctacctggac
    13141 gagcggagcg gccgatgagc acgatgaagg ccgtcgtcac cacggcagtc ggtgagccgg
    13201 acgtgctgcg gctgaccggg gtggagcggc cagcacccct gccgaccgag gtactggtgc
    13261 gggtcgaggg cgcgggggtc aaccccgtgg actggaagat ccgttcgggt ctcttcccgt
    13321 ccggcgcgct cggcgcaccg ccgttcgtgc agggctggga cgtcgcgggg gtcgtggagt
    13381 ccgggccccg ggtgacgcgg ttcgagcccg gcgacgaggt gttcgggctg atcggcttcc
    13441 ccaggcccgg cggcgcctac gccgagtacg tgaccgcgcc cgcgcggcag ttcgcccgca
    13501 agccgacccg gctgagcttc gaggaggcgg ccgcgctgcc gctggcgggg ctcaccggct
    13561 ggcagacgct ggtggagacg gcccggatcc agcggggcga caaggtgctg gtcaccgcgg
    13621 cggcgggcgg cgtcggccac ctggccgcgc agatcgcccg cgcgcacgac gcggaggtca
    13681 ccggcacggc ccgcgccgag aagcacgact tcctgcgcga ggtcggcgtg gaccacccgg
    13741 tcgactaccg caccggcccg ctgcaccaca cggtcaccgg tcaggacgtg gtgctcgatc
    13801 tgctcggcgg ggagcacagc ttcgagctgc tgcgcaccct gcgcccgggc ggtctgctca
    13861 tcaccgtgat cggccacgtc agccccgaac tcgccacata cgccgccagc ctgggcgtcc
    13921 gggtcacggg cttcctggtc gagccggacc actccgggct ggaagccctc gccgcgctgg
    13981 tcgaggcggg ccggctgaag gtccgtgtgg accaggtgtt caagctcgcc gaagccgcca
    14041 aggcgcacga gtacggcgag tccgaccgca ccaccggaaa gatcgtgctg gtcccatgac
    14101 gtcacccttc gccgcgaacg gcccggccgg gcgccttctc gcccgtatcc gtccggcagt
    14161 tcaggtccgc cggaaggaac ggcagcgcac ggccgcgccg cacgacggcg agggaggcgt
    14221 ccccgccccg gcaacagccg ccgccgggac cctgcgcccc ggcggcggcc tgccggaccg
    14281 gctggtcacg gtgctcgccg tggccgccgg tctggcggtg gccaacatct actacgcgca
    14341 tccgctgctg acgtcgatcg ccgcctcgtt cggcgtcggc agcaccgccg cctcgctggt
    14401 ggtgaccgcc tccaccgccg ggtacaccgt gggcctggcc ctgctggtgc cgctcggcga
    14461 cacggtgaac cggcgccggc tgctggtggc gctgctgctg gtgaccgcgc tggggcaggc
    14521 cgcctcggcc gccgcgcccg gcatcggcgc gctggtggtg ctgtccgggc tgatggcggt
    14581 gacggcggtg ggcgccccgc tgctggtggc gttcgccgcc gccctcgccc ggcccgaaca
    14641 gcgcggccgg gtcaccggcc ggatgctcag cggggtcctg ctcggtgtgc tgctcgcgcg
    14701 gacgggcgcg ggtctgctcg ccgagtggac cggcacctgg cgctcggtgt tcgcggtcgc
    14761 cgcggccggg atgctggtgc tcgcggccct gctgtggcgg ctgctgcccg acctcgaacc
    14821 ggccgaacgg ctgggctacg gacggctgtt gcgctcggtg gcgtccgtgg tcgccgagga
    14881 gccgctgctc aggctgcgct gcctgtacgg cttcctcacc ttcgcctcct tcagcgtgtt
    14941 ctggacctcg gccgcgttcc tgctcgccga ggagccctac gcgtacggcg aggccctgat
    15001 cggcgcgttc gggctgctgg gggcagccgg ggcgatcgcc gctcgggcca tcggtccgct
    15061 ggtggaccgg ggccgggacc ggctggcctc gaccctgctg tacggggcga acctcgccgc
    15121 ctggggactg ctcgccctgg acggcggcca cctgctggtc tgcctggtgc tcggggtgct
    15181 gctgctcgac ttcggtgtgc agggcgccca ggtgaccaac ctcggcgtgc tctaccggct
    15241 gcggcccgag gcccgctccc ggatcacgat ggcctacatg accgcctact tcctgggcgg
    15301 ggcggcgggt tcggcgctgt cgggcgccgt gcactcggcc gccgggtggg ccggagtgtg
    15361 cgcggccggg ggcgggctcg ccgcactcgt actgctgctg tggggcctgg agcaggcgcg
    15421 ggcgtagcgc gtcccttttg tgcattcctc cgctcaggaa cattccaacc ctggagttct
    15481 cgtgtccact gcttcgacgg gtgccgctcg gtcccgtccc cttctcaccc tgatcgcggt
    15541 ctgtgtctcc tgcggactgc tgcccgcctc cctcaccgga acctccgtgg cgctgcccga
    15601 cctcggcagt gacctggacg cctcgctggt gaccgtgcag tgggtcgtca acgcctacaa
    15661 cctcaccttc gccagtgtga tgctggtggc cggctcgctg gccgatctgc tcggcaggcg
    15721 gcggatgttc acggccgggc tcgtggtgtt cgtgctgtgc acggccggtt cggcgctcgt
    15781 ctccgaggtc gtggtgatcg acgtgctgcg cggcgccgcg ggcgtcggcg cggcgatggt
    15841 gctcaccgcg gcgaccgcgc tgctcgccca gtcctacgac ggcgccgccc gcgcgagggc
    15901 gttcgggttc ctcggctcct ccttcggcct cggcctcgcg ctcggcccgt ccctgtccgg
    15961 gttcctggtc ggcgcctggg gctggcgctc ggtgttcctc gcgcacgccg ccgtggccgc
    16021 cgccgtcctg ctgctgcgcc cggcgctgaa ggagtcgcgc gacccggagg ccgccggtgt
    16081 cgactacggc ggcgcgacca ccttcagcgg cgccctgttc tccttcaccc tcgccctggt
    16141 cgagggcccg caactgggct ggacgcaccc ggcggtactg gccctggcgg tgctgtcggt
    16201 ggccctgatg gcggcgttcg tacggatcga gaagcggcgc gcgaggccga tgctggagct
    16261 gtcgctgctg cgcgagccca agttcgccgc ggtcagtctg atgccggtgc tgctggcctt
    16321 cggcttcgtg tgcctgctgg tcttcctgcc gtcgttcttc atcggcgtga acggcatgag
    16381 ctcctcgcgc gccggtctga cgatgctgct gctcagcggt ccggtgctgg cgctgcccgt
    16441 ggtcagcggg gtgctcaccc gcagggtgtc cacctcggtg ctgctcgggg tgagcctgct
    16501 gctggtggcg ggcggcgcgg cctggctcac cgtcctcgac caggacgcca cgaccgccgt
    16561 gctcgccggt ccgttgctgg tcatcggcac cggtgtcggc atctccttcg gcctgctcga
    16621 cggtgccgcg gtcggctcgg tggacgcgag ccgggcgggc atggccgccg ggctgttcaa
    16681 caccatgcgg ctgaccggcg aggccgtcgc gatcgccgga atgggctcgg tgctggtcag
    16741 cctcacccag agcaatctgc gcggctggag cggcggcgac gtcgacggcc tcgccaacca
    16801 ggtcgtgcag ggcgagatcg gcgccgccgc cgacgaactg cccgccgccc agcaggcgga
    16861 cttcaccgcg ttcgccgccg acgcctacac cgacgccctg cacaccgtgc tgtggctgct
    16921 ggccgccgtg tgcgcgctgg gcgccccgct gatcatgcgg atgctgcgcc ccgccccggc
    16981 cgccgaggca ccggcggccg ccgaccgcga cgacacccgg gaaccgatca cgatgggaga
    17041 gacctcatga gcacacccga cacccggccg gtgctggtcg tcggcgcggg cccggtcggc
    17101 ctgaccgccg ccgccgaact ggcccggcgc ggcaccccgg tacgcctgat cgaccggacg
    17161 gacgcgccga gcccgctgac caaggcgctg atggtctggc cgcgcaccct ggaggtgttc
    17221 cgcggactcg gcgccgacgg ctacatcgac aagcacggcc tgccggtgca ctccttccgc
    17281 tacaactccg gcaccgaccc gatctgcgac atcgtcttcg gcgaccgcac ccggccgatg
    17341 gtgatcatcc agccggacgt ggaggagctg ctgcgcgagg cgttcacccg ggcgggcggc
    17401 cggatcgagt gggagaccga gctgacccgg ctcagccagg accccgacgg cgtgctggcc
    17461 accctgcgcg ccccggacgg caccgagacc accgaggagt acgcctacgt cgtcggcggc
    17521 gacggggcga gcagcaccgt ccgcaaggcg ctgggcatcg agttcaaggg cgccacctac
    17581 ccgaacgtgt tcatcctggc cgacaccgag atcgacggcg acctccagcg cgacgccgtg
    17641 cactactact gcaccgagaa cgggatcatg gtcctgatcc ccctctacaa cggccgcttc
    17701 cgcgtgttca ccgcgggccc gcccggtctg cgcggcgagg acctcaccga ggagctgctc
    17761 caggacttcg tcgacaagcg gggccccggc gggctgaagc tgtacgacgt ctcctggaag
    17821 accacgttcg cgatccacgc ccggcacgcc gagcggttcc gggccgggcg ggtcttcctc
    17881 gcgggcgacg ccgcgcacat ccacagcccg gccggcggtc agggcctgaa caccggggtg
    17941 accgacgccc acaacctcgc ctggaagctg gccctggtgc accgcggggc ggcggctccc
    18001 gagctgctgg acagctacgg cagcgagcgg gcggcggtcg cgcagggcgt ggtgaagcag
    18061 gccgaggtgc agacgaaggc gtggatgctc tccaagcgct ggcagatcca gctgcgggac
    18121 gtctccgccc ggatggccga gcgctccggc gtcttcgacc ggttctactc gccgtggctc
    18181 gcgggtctga ccaaccacta cccggcgggg ccggcggtcg acgaggagca gggccgccga
    18241 ctgcgccgca ccggaccgcg caacggccac ctggtggcgg acgcggccct gcgcgcctcg
    18301 ctgccggtcg accggtacac gctcctcgtc acgctcccct ccggcccccg ccccccgcgg
    18361 ctggccgagg tggagaagtc gtacgacgaa ctggtgacgg tccggacgaa gccgggccgg
    18421 cgcttctcgg cggtcctggt ccgcccggac cactacgtcg cagcccagga ccacgccccc
    18481 gaactgaccc gcgttctcgg ccatctggcc acgctggccc cggccgcact catcgaggaa
    18541 ggacacagcg catgacgcag cagcaggtcc gcggcaccgc ggacaccgtt caggagttct
    18601 tcggccggtt cggcacgggc gatctggccg ggcttgcgga gctgttcgcc gaggaggcgg
    18661 agctggtcgt ggcgggcgcc cccattgtcc cgtggacggg gcgcctggtc ggccgccgtg
    18721 aagtggaggg gtacttcgag cggttcgtgg cagccgtgga cacccagctc ttcgatgtgg
    18781 agcggatagc ggtggacggc gaggacgcct ttgtcctcgg ggagttctcg cacaaggtgg
    18841 tctcgaccgg gaagaccttc tcgggcccgt tcaccatccg gatcacggtc cgggacgggc
    18901 tcatccagcg gtaccagacc ttcgaggact cctacgccgc cgcgatggcc ttcggttccg
    18961 actgaccgtc gtcgcccgcg gtgtcctcgc cgggccggtc cggttcgtcc gggccggccg
    19021 cggcgaagaa ggcgtcgagc ctgtcccgcg tctcctgcac cgtcggcatg tgcaggacca
    19081 gctggacctc gtggtcggcg gccagctccc actcgtgcac gtcgaagctg agccctccga
    19141 cggtgtcgtg cgtgatctcc ttcgctcggc tcgggctcgg ttccagcacc tcgtgactgc
    19201 cccacagccg cttgaactcc gggctgcgct cggtcagctc ggccaggacc cgctccacct
    19261 cggggcgtcc gtagcagtcg gccacgtccg cgcggaagcg ggcgaccgtg ctgcgggcga
    19321 gcgcctcgga gtggacgtag cggcggcggc aggcctcgtt ggtgaagtac tccaccagga
    19381 tgttctgccc cggtcccccg atgcccagga actccgagac ggccgagttg gcggccagga
    19441 tgttccagca gcggtcccgc accagcgccg ggttggggaa ccagtggttc acgatctccg
    19501 cgagccgcgc cgggtcggcg ggaccgctgt tctcccgctg gtcgacgtcc ggtgtcttca
    19561 gaccggccag ccggtgcagg tagatctcct cggcggggtt gagccggagc gcgccgctga
    19621 tcgcgccgag cacggattcc gagacgttga tgtcccggcc ctgctccagc caggtgtacc
    19681 aggacgtgcc gacgcccgcg aggacggcga cctcctcccg gcgcagtccc ggagtacgcc
    19741 ggcgacccga ggcggtgagc ccgacttccg ccggggacag tcgcattcgc cgggtccgta
    19801 gaaagtgaga caactcttct agttgacgct ttcggcgacc tatcgtcatg aatcacgagg
    19861 ctgtatcaag ggcaataacc agtcaagcaa aaggttcgtc aagggtggct tgaaaacgcc
    19921 aactcaggct catctcccca cagaacagca ggtcttgagc gagcctcgac ccggtttcga
    19981 gcttgccgag tggctgaatc cgacccctgg ataaaggcgg atttgagacc tccactttca
    20041 gccaacgcgc aattctgatt cgcggttcac atacccacgt gcccgctttc ccgaaagggt
    20101 gacggaaaac actagacggc cagcaaagga gaggcgccct tccgccactt gaggatcttg
    20161 tcgaagctca ccacggcacc gcccagaccc ggctcggtgc cgaagtggac gtggtccgcg
    20221 agctcctgga tgagatacag cccccggccg ttctccgcct ccgcggacag ccgccccgcg
    20281 tccccgcccg cggcaccgaa gcccggcccg gagtcggcga cctcgatccg gcaggtctcg
    20341 ccgtccagat aggcggtgac ccggtacgcc tccgccgccc cgtcgagcgc gccgtccccg
    20401 ccgtgctcca ccgcgttcgc acaggcctcg ctgagcgcga cggacaggtc gtaggagatg
    20461 tccgggtcca cgcccgcgct ctccatcgtg ccgagcagca gccgccgggc gagcggcacg
    20521 ctggcagcct cacgccgcaa atggagtgac caccagatgc tcatgctcca gcctcccggc
    20581 cgcggctcga catacggtta cgtattgccg tccgcgcccg tgtgtaagcg cattgttgac
    20641 gtgataccgc ccatatgggc gatgcgccgg aagtcgtcaa cggtgtatgt ggggctggtt
    20701 cacacgtaag ggggattcca cgcgtaggtc atcttgcgga cctgccgtgt gggggcccag
    20761 gggccggtgc gatgatgggg ccgccatgag tgccccccac ccccagcgca cgacgcgcgc
    20821 cggacgggac gtccgggttc tgcgggccgc ggtgttcgcc gcggtctgcg tcgtgctggc
    20881 cgcgggcggg cacgcgctcg gctcctgtgt gtccatcccg ctgtggacgc tgggcgccgg
    20941 tttcctcgtg gtcctcgccg tcgccgtacc gctcgccggg cgggagcgct cgatgcccgg
    21001 catcgcggcg ctgctcgcgc tcggacaga
//
