LOCUS       NZ_CP104794            26329 bp    DNA     linear   CON 09-JUL-2024
DEFINITION  Streptomyces sp. FZ201 chromosome, complete genome.
ACCESSION   NZ_CP104794
VERSION     NZ_CP104794.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. FZ201
  ORGANISM  Streptomyces sp. FZ201
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8604396)
  AUTHORS   Zhang,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2022) College of Life Science and Technology,
            Jinan University, Guangzhou, Guangzhou, Guangdong 510632, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2021
            Assembly Method                   :: unicycler v. 3.14.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 235.1x
            Sequencing Technology             :: Illumina NovaSeq6000; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025402955.1-RS_2024_07_09
            Annotation Date                   :: 07/09/2024 06:54:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,562
            CDSs (total)                      :: 7,471
            Genes (coding)                    :: 7,336
            CDSs (with protein)               :: 7,336
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 55 of 135
            Pseudo Genes (incomplete)         :: 92 of 135
            Pseudo Genes (internal stop)      :: 7 of 135
            Pseudo Genes (multiple problems)  :: 18 of 135
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:45:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4094910
            Orig. end                         :: 4121239
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP104794.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zhang Fei, College of Life
            Science and Technology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26329
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="12"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26329
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26329
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16329](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16329)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(706..2238)
                     /locus_tag="N6J21_RS18245"
     CDS             complement(706..2238)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018518287.1"
                     /locus_tag="N6J21_RS18245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /protein_id="WP_261718818.1"
                     /transl_table=11
                     /translation="MKGSTHRRCYCRDPHTDKPLGKKCPKLSSRKHGSYSIRQELPPRE
                     DGTRRSFSRAGYESLKDAQADLDHVRSLLALAEKDDPDSLQRLVDMLEEVAVEKAPLPA
                     IEETRRRLRAGLALRGSLTVGEWLDQWFAAKKRRKTTLNGYASHIRVHLKPRIGHVRLD
                     RLNVGHLVEMFDGIADDNEVIVAENEARREQIARCKPSKPGRPVGAERKLLAAERAKLE
                     EMKPFRKITGPASRQAIRRTLRAALNSAIAQQLITFNPASHVELESGKRPKPLLWTDER
                     VRRWRATDEIPGPVMVWTPQQFGAFLDAAEGDRLYAIFHLMGTRGLRRGEAVGQDWHEI
                     DLDAGLITPAKEIVVDGWDPYESEPKTDGSANTIALDSTTISELRDHKARQEKERAKWG
                     DAWQDTGKVFTKEDGSWLHPGTVSETFRRILATTDLPPITLRDLRHVAATLTHGGGGDI
                     HAVKETLRHSTITLTSDTYTSLLPELDREIAEKAAKLIPRSRPAGTDSSASA"
     gene            complement(2235..2921)
                     /locus_tag="N6J21_RS18250"
     CDS             complement(2235..2921)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009321526.1"
                     /locus_tag="N6J21_RS18250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_261718819.1"
                     /transl_table=11
                     /translation="MTQHGWDAGGDEDDVPEWVDQVMATVAAEVRRRRKELGMSAQDLA
                     DRCEEIGHPIPRNVIANMESGRRANLPLVDVIVLAEALRTYPICLLYPVGYVDRVQRLP
                     LQHSEPTWDAMRWFTGDSEDFGLEDDMLRSFRAHVRHQRAALAALKGEKHERWKAETAP
                     NHAEREEAVLAQADYAERALEAKYRLRSARAFIREDGGTPPHLPPELSDVDPPDTDPST
                     TEENDL"
     gene            3016..3246
                     /locus_tag="N6J21_RS18255"
     CDS             3016..3246
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961488.1"
                     /locus_tag="N6J21_RS18255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_261718820.1"
                     /transl_table=11
                     /translation="MRENELTGRVKGMSREELLELPAAVDLETGNRALGLGRSKGYELA
                     KRGQYPCKVLRLGNAYRVVTADLLALLGLAA"
     gene            3480..4793
                     /locus_tag="N6J21_RS18260"
     CDS             3480..4793
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999992.1"
                     /locus_tag="N6J21_RS18260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3631 domain-containing protein"
                     /protein_id="WP_261718821.1"
                     /transl_table=11
                     /translation="MQPENPESYSAPAQAVWPAAAIPGRPGAHLRAAQADGADPRPSGG
                     ADARSADEAEAPSGLEEIPDAGPTHGSKLLDELRAQIAQFVIPPSPEALDAITLWVAAT
                     HLQPAWQHAPRLAVVGPAKRCGKSRLLDVLTETVHEPMLTINTTPAAIFRSITEENPPT
                     LLVDEADTIFGTPKMAEKNEEMRGLLNAGHQRNRYVTRVVGNDHTPHRFATFAMAAIAG
                     IGDLPDTVMDRAIVIRMRRRAEGEKVKPFRSRRDIPALHELRDRIHAWAQPLLDEAANL
                     EPDMPVEDRAADTWEPLVTVADLAGGRWPRLARVACARMVAAEEAAEEDHPSGARILAD
                     IRRVFVAQREVDSLSTEELLHHLRQDPEAPWAEWGRGGLNARELGRMLSAYEIKSGNVR
                     MADRTQRKGYMRNKFLDAWRRYCPAVHPVDADTTHGED"
     misc_feature    complement(5203..5221)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            5219..6145
                     /locus_tag="N6J21_RS18265"
     CDS             5219..6145
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009327614.1"
                     /locus_tag="N6J21_RS18265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2637 domain-containing protein"
                     /protein_id="WP_261718822.1"
                     /transl_table=11
                     /translation="MSRRRDRPLRRDQPGLEQPAKTKLTAEQYVLRTAGVDIVALTAGA
                     FWLSYAHLADVAGQHGLRDSPTRRWAWPATLDAFIVAGELLMLRAGLRRVTDKWAISVT
                     AIGSVGSIGLNVAGVTGTREVGSVPLLDYVVAAVPPAAAMVAFGVLMRQIHELVAQPAV
                     DRSAPDSAQVPQPPSTPSVHRAEAPTTVVGPSAEVPAEGVRPADLLVQPGRTTEPPTAA
                     SVQPPESPADAAAGKPRGGRPPGAPLEVLVEIGRAAAAEQGKLTRTVVRTAVEDKGLTI
                     GSKRLTDVMDILRAEPEAPAETDRPDD"
     gene            6317..7060
                     /locus_tag="N6J21_RS18270"
     CDS             6317..7060
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002505.1"
                     /locus_tag="N6J21_RS18270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_261718823.1"
                     /transl_table=11
                     /translation="MTHDPLHPDDTPDELPMLTKSPTLMDRWRRAFGRAAPGGASSTPS
                     PTHGRSSGVSAPGVAEEAQRQGAPGQDVGTEGSPDEDTLRTVQRETLRPVRATDTAESV
                     GGEPVVKSVQPTIRRFTGDKRKERVGPLRFTTDQLGLLQEATAEHGYKGEGGFAADVVV
                     AFITGRFTANLPLSEDRRRTHHFRAQVLRQLNRIGVNVNQIARALNSDHTPTDIRQHLT
                     ELRQLLELIAEALRQPTDPDTEAAA"
     gene            7057..8772
                     /locus_tag="N6J21_RS18275"
     CDS             7057..8772
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002506.1"
                     /locus_tag="N6J21_RS18275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="WP_261718824.1"
                     /transl_table=11
                     /translation="MIAAIKPAGSNTRGLLAYLYGPGDHDEHLDPHIVAGFAMLGMPDP
                     GRDENATLTELARYLDQPVRLRNSEFGKKATDHVWHCPVRTAPEDRYLSDTEWGEIAQR
                     IVQAAGIAPAGDDLACRWIAVRHADDHIHILATTVREDGRRPKLHDSGIRVGDACREIE
                     KDYGLRQLKKGDRTGARRPTQAEMHKAERLGWEQPSPAWLQDRIRAAIPHVTNAEEFIA
                     YLEASGVEVQVRRGPSGDLLGYAAGRPGDVNEAGEQIYHPGSKISPDLSLPKITTRLES
                     SRPEEHPTARRNHPSTPWQQATDALDTLHTDLADDTHAQAHITALGELLEATAQRAPAN
                     LRTELQAAAKAFARAQRSQIRAEDRAAHALRSAARDIVHTATGPDGSALAAMVAALVWA
                     AIVTARWHEAKNHAHQADAARQAVQHLQMAADRALAPTLAELTARPPREQTRRVLANDV
                     RAAVPDHAERILADPAWPALATVLADADARGHQPHQLLKEAAAQRELTSARQPARVLIT
                     RIQHTGRNPAPNRRAEAARRRSTITPSVRVQQIQNGQTPSTTTTPAEQQHRRRR"
     gene            complement(8779..9912)
                     /locus_tag="N6J21_RS18280"
     CDS             complement(8779..9912)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999997.1"
                     /locus_tag="N6J21_RS18280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_261718825.1"
                     /transl_table=11
                     /translation="MDPHGSTAQRFPLVARFRPACLPLPERVRALVDLADTAVKETDQG
                     LASAAYNQAALIASDLDLPDLAREMCHQHAAAYLHACPLPGMSAIRGLEPVVNLARLQI
                     RAGHADESRQRLLNLYKAVEAGAAARFEHVTVPANLTATGEDRQEVRAWLWRVLLADGT
                     RTLTTEGRWAEALAHIEAHHGIGKRMLDGRQVAVLAALVAGDTAWAAALLADTMPGDPW
                     EQAVTTCLTVLCRRDAGQPIDGHLADLVTVHSGRKTEPGMIVFDTRLGLTVLDAIGSAE
                     ALTAHGVVEDLHRRTTDAEDGYAAREILAHPLYTEIATDRQVQNCRALVRACALGSGAL
                     PDELRGELTAALRASDRVIRESLARSSDPGGTQPLRL"
     gene            complement(10001..12082)
                     /gene="fxlM"
                     /locus_tag="N6J21_RS18285"
     CDS             complement(10001..12082)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543781.1"
                     /locus_tag="N6J21_RS18285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_261718826.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.6e-27, bitscore:
                     95.0, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 2.3e-45, bitscore: 153.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPDRWQQHNITFVDRDIAQRTIAERFGPTLIEAEADGQLTDWWF
                     MNKQPWPLRYLADKPSPAIESLLSDLIGDGVAASCLPCIYEPETDTFGGPEAMDTAHEL
                     FHSDSRHLLTYQPSPMRLGRRETAVLLASVMMRGAGLDWFEQGDVWAKVAALRPATAPQ
                     PPERAAALAPAMRKLMTADAHGLCRPDGPLHAHEEWVTAFERAGATLADLAGRGALTRG
                     LRAVIAHHVIFHANRAGLLRDDQSALSHIAREVVMGTSDHTEPSTEATADADSVGSVNT
                     DTITTPTADAERLRNALVDQLRADGHARTPAVETALRTVPRHVFVPDASLEDAYANAPV
                     HIKYDTDGTSISCASQPGVVALMLDQLEAQPGERILELGAGTGYNAGLLAHLVSENGHV
                     TTLDVDDDLVEGARAHLAAAGITNVQAVTRDGALGYVEAAPYDRIIATVGAHGVPHAWL
                     QQLAPGGRLLVPQRLKGTVSRSITYELRDGRWMSLGSEMNTFMPLRRGIADDDRRVIPL
                     STDGAVRLQAPAGLNIDAEALAGVLDQPRTEEWTGMTVRAMESPEWMELFVTCSLPSGL
                     IRMLFPQSTKGTLLTEDPYPSSTAVVDKGAVTYLARRLSEKRTPEGGKLWEFGVIGHGP
                     GSDELTAKVADAIRTWDREYRSREATFEIQPLDAPSIERRPGLFALETPLNRIVVDWQ"
     misc_feature    complement(12038..12052)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(12104..13378)
                     /locus_tag="N6J21_RS18290"
     CDS             complement(12104..13378)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543780.1"
                     /locus_tag="N6J21_RS18290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_261718827.1"
                     /sec_met_domain="LANC_like (E-value: 4.4e-43, bitscore:
                     146.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAHPPLGLVDAIAARLADPETMPHGSRTLCSDRQHLAYGPPGIA
                     LLHIELAANGLSPWHRAHDWLAAASRQPLTSGPDSHPFYGVPAFAHALSCAADHLPGSY
                     QRALDAMDAQIAVDVGRRLDAAHRRIDAGRLPQLAEFDAIRGLTGYGAYLLRRSPGSST
                     TRAVLDYCVRLTEPITHHGETLPGWWAGTGPSGSPDDRFPGGHANTGMAHGIGGVLALL
                     ALAARNGSVTDGHHAALHTILAWLDRWKEEADGGPVWPYWVTQGELRSGHLAPSAPRRP
                     SWCYGTAGLARAQQLAALALGDTRRQIDAENALVTALTDPEQLKATTDNGLCHGFSGLA
                     HVAARTADDARPSTGEKLRAAIPALLAAVIPPGTDPELTATAFIQDEESGPGFLDGAAG
                     IALALLAPSTAAPPRSPWDTCLLIA"
     gene            complement(13375..16329)
                     /locus_tag="N6J21_RS18295"
     CDS             complement(13375..16329)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543779.1"
                     /locus_tag="N6J21_RS18295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_261718828.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.5e-203,
                     bitscore: 674.4, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.2e-18,
                     bitscore: 65.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.7e-23, bitscore:
                     82.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAWLRAVWANKDVAEALRHSSPVLATQVRALCTAEHPALRDVQRA
                     AMSVARYLLRAQHRATPFGLFAGVATAEFGPQARADWSEEHVAVGRAGAEWLAAVVERL
                     ESCPDLLERLPVVVNHTVTYRGDRLVVPFQPDVQDDRTRAVEASLALTEPVRAVLAAGR
                     LPIRFGTLVEKLQAEFPEAGPEKAGQLLAELIRRRVLITGLHAPSTETDALGYLVSQLD
                     VIDAGSLAPVAETVRELHAVRAGLEECTTHGSRDSVAARMRDLIPGLRRHPVALDLRLN
                     AQIVLPEAVAREVERAVLVLTRLSSRPYGTAAWNEYHQRFYERYGIGTMVPLAEVVADS
                     GTGYPDGYPGAPASPRRPRVSARDDVLVRLAQAAALDGRDEVILTDEQIEALDVGPDEP
                     RLPPHLEIGVRVYAASLEELQRGRFRLEVVSVSRGAGVSMGRFLSVLAPADREALVTEL
                     ADLPAADGNTVPAQLSFPPLLSESAHVTRSPQVLPAVISLQEHRVPQDTVLTPEDLAVG
                     CDGRRMYLAVPERGHRVEAVGMHALNLRTHTPPLVRFLTELSRAQCAQVTVFDWGAAAA
                     MPFLPRVRYGRTVLAPARWRLEASELPGHARPRTEWDAALSNWRARRRLPRPVYLVEDD
                     RRLFLDLDEAGHRALLRRHLDHSRLAVLVEAPEREAYGWCGGRAHEVVVPLKATGPSVW
                     PPLPAPSRGRALSSTQMQTPAASSVLLAALYGAPRRQDVLVSQHLPGLLERLGNPSWWF
                     IRFRDPDQHLRVRIALPDAQAFADTARTVSAWADELRSIGLLADLRYPTSYREMGRWGS
                     GAAWEAAEEVFRADSRAVLAQLAQPQRPSQRTLVAAHTVAIASAFLGTTEAGMRWLIDR
                     VSPTATMPVPRPQFTEAVRLADPSDDWSALRSVPGGDAIVSGWVDREAALATYRPHLPG
                     PDTQGIAVDDVLTSLLHVHFVRHVAVNFPEEEVCLYLARAAALAWTARPRGRAS"
     aSDomain        complement(15709..15984)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_N6J21_RS18295_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.20E-20"
                     /identifier="RREFam001.1"
                     /label="N6J21_RS18295"
                     /locus_tag="N6J21_RS18295"
                     /protein_end="207"
                     /protein_start="115"
                     /score="65.0"
                     /tool="antismash"
                     /translation="VVVNHTVTYRGDRLVVPFQPDVQDDRTRAVEASLALTEPVRAVLA
                     AGRLPIRFGTLVEKLQAEFPEAGPEKAGQLLAELIRRRVLITGLHAP"
     gene            complement(16551..16730)
                     /locus_tag="N6J21_RS18300"
     CDS             complement(16551..16730)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825826.1"
                     /locus_tag="N6J21_RS18300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_030750825.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 5.2e-13, bitscore:
                     47.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSTVVPSRTEVRPHIPGASDGFDLDVSLVEIADPAGLVNLTDD
                     NCGSTCGACTTNVA"
     misc_feature    complement(16907..16923)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            complement(16921..17109)
                     /locus_tag="N6J21_RS18305"
     CDS             complement(16921..17109)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337811.1"
                     /locus_tag="N6J21_RS18305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_261718829.1"
                     /transl_table=11
                     /translation="MEWPWITGDCWLGCGRTGVLVIWLGPVQWDGQHAPFYTCEPCLDR
                     LKAQALAYFMERRPASA"
     gene            complement(17336..17782)
                     /locus_tag="N6J21_RS18310"
     CDS             complement(17336..17782)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337800.1"
                     /locus_tag="N6J21_RS18310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_261718830.1"
                     /transl_table=11
                     /translation="MTSLRTPVEALPVGHPTYSQTFPCEPSTAELGRDLVRDVLGVWHL
                     DGLADRAALIITELIANASRHTPCPEIRLMVRRPSATRLRVGVLDREPSRLPILSQAAD
                     DDESGRGLLLVDAVADRWGYDLHGSDRRPWGKEVWAELRTEGGK"
     gene            18024..19307
                     /locus_tag="N6J21_RS18315"
     CDS             18024..19307
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000004.1"
                     /locus_tag="N6J21_RS18315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_261718831.1"
                     /transl_table=11
                     /translation="MDTTRNTVLEAWMTEHGYSSNSLAEAVNRAIERLTGRPGGLDGSS
                     VRAWKAGRVTWPKSAARKALEDVTGLPAVALGFVPRGRPSSTPAPPQQEDPDMKRRTLV
                     GSIAAAAAAAAAPGTASPRRIGMSDVNRLNKRFAEIIASDHRHGGQLGIEQRAAALADE
                     ALNLQNAGSATQRVRSNLYASAAAFRSSAMWAAIDGRRYDVAKAHMREAQALAEMSGDQ
                     AIKFRIWSHAGTMYRHMGRPADAFAANDVARNLHLTRRDPLFASLGLARQGAIHGTAQD
                     RTGTRRAFEQAQDAMLRADPADYRPVWMLAFYDQAELDSLALSAHLALGDYSTAEYHAH
                     RCLSALRPHMIRSRAITTTRLAHAQLAQGAPDAATATAMKVPAEAATQHARVTRMLQEF
                     GAALRATAPGSSSVQTWTEHAAAWRMAA"
     misc_feature    18249..18251
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19304..19843
                     /locus_tag="N6J21_RS18320"
     CDS             19304..19843
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337821.1"
                     /locus_tag="N6J21_RS18320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_261718832.1"
                     /transl_table=11
                     /translation="MTTAPAIELRTFTTLDTARGDLLDVYADVRAPLLHLPNYAVTAFG
                     ERLDRHGTEPGFTAVLAYAEGHPVGYAYGNTIEHGDRYWQRTSPTPAEKYTERPAVALK
                     EIGVRPTWRKTGTARRIHDTLLATRDEPYVTLMVNSTAGDGKVHALYLSWGYEDIGQSQ
                     PSPASPVLTVMIRTIR"
     misc_feature    19891..19906
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.76"
                     /tool="antismash"
     misc_feature    20287..20302
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 22.28"
                     /tool="antismash"
     misc_feature    20328..20342
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.8"
                     /tool="antismash"
     misc_feature    22563..22579
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.28"
                     /tool="antismash"
     misc_feature    complement(22913..22922)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.29"
                     /tool="antismash"
     misc_feature    22948..22968
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.19"
                     /tool="antismash"
     misc_feature    complement(22966..22986)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.77"
                     /tool="antismash"
     misc_feature    complement(23163..23178)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.19"
                     /tool="antismash"
     misc_feature    23164..23177
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.87"
                     /tool="antismash"
     misc_feature    23347..23361
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.0"
                     /tool="antismash"
     misc_feature    23366..23381
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.83"
                     /tool="antismash"
     misc_feature    complement(23416..23430)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.6"
                     /tool="antismash"
     misc_feature    complement(23781..23796)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.9"
                     /tool="antismash"
     misc_feature    complement(25461..25476)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.03"
                     /tool="antismash"
     misc_feature    complement(25914..25927)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.93"
                     /tool="antismash"
     misc_feature    26299..26313
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
ORIGIN
        1 cagttcgtgg tggccacggt gacctcgggc cggttcgaag catgcgttgt cgacctcgat
       61 gatgaggcgc ccttcacgga atggggcgaa ttcgaacaag gtctcagctc gccggtcgtg
      121 gagatcctca gctggagcga ccaagccgaa tacgtcgccg ctgatgtctc ccgccttgct
      181 gcgacggtcc gggtactcgc ggctggcttc gcgcgccggc tcgatccctg gcagtcggag
      241 gtgctggtcg cgttcacgct ggacgtgcgc gtggtgttcg gtgcagagtc gcccacagcc
      301 ctgtcggtga gcggctcccg gccggtcgag gacgctgagg aacctgctgc catggctgct
      361 gcggagcgcg cccgtctcac gctcaggtgg tagtgcgaag gctcagcgaa atcgcccgcc
      421 aacccactga tcggggcaag ggtcaccaga ggccagtgtc agccgtgtcc ggtccgtccc
      481 ggtgcaccag gtgccgcgag agtgcccgca gcgtgggttt tccccgcgag aactccgcga
      541 cctgcaattt cccacgactt gctggaggag accgtccggc aggctccggc cgtcctctga
      601 gcccagatcg gccaactaga agacaccggc gcttctgggt ggctcaaccc tacgaatgga
      661 tcggcctacc cgtcccagga acgtaaggcc aactagcgct cctagtcacg ctgaagcgga
      721 agaatcggta cctgccggac gtgaccgggg gatcagcttc gctgccttct cggcgatttc
      781 acggtccagc tcggggagca ggctcgtgta tgtgtccgag gtcaacgtga tggtggagtg
      841 ccgcagggtt tctttcacgg cgtggatgtc gccgccgcct ccgtgcgtga gcgttgcggc
      901 gacgtggcgc aggtcccgca gggtgatggg cggtaggtcg gtcgtggcga ggatgcggcg
      961 gaaggtctcg gagaccgtcc cggggtggag ccacgagccg tcttccttcg tgaagacctt
     1021 gccggtgtcc tgccaggcgt cgccccactt cgcgcgctcc ttctcctggc gggctttgtg
     1081 gtcgcgcagt tcggagatgg tcgtgctgtc gagcgcgatc gtgttcgcgc tgccgtccgt
     1141 cttgggctcg gattcgtagg ggtcccagcc gtccaccacg atctccttgg cgggagtgat
     1201 gaggccggcg tcgaggtcga tctcgtgcca gtcctggccg accgcctcgc cgcgacggag
     1261 gccgcgggta cccatgaggt ggaagatcgc gtacagccgg tcgccctcgg ctgcgtcgag
     1321 gaaggcgccg aactgctgcg gggtccacac catgaccggg ccgggtatct cgtccgtcgc
     1381 gcgccagcgc cggactcgct catcggtcca gagaagtggc ttcggacgct tgccggactc
     1441 caactcgaca tgggacgccg ggttgaaggt aatgagctgc tgggcgatcg cggagttcag
     1501 ggccgcgcgc agggtgcggc ggatcgcctg acgggatgcc gggccggtga tcttccggaa
     1561 cggcttcatc tcctccagct tggctcgttc ggctgcgagc agtttccgct cggcgcccac
     1621 ggggcggccg ggcttactcg gcttgcagcg ggcgatctgc tcgcggcggg cctcgttctc
     1681 ggccacgatg acctcgttgt cgtcggctat cccgtcgaac atctccacca agtggccgac
     1741 gttgaggcgg tcgaggcgta cgtggccgat gcgtggcttc aggtggacgc ggatgtggga
     1801 ggcgtagccg ttgagcgtgg tcttgcggcg cttcttcgcg gcgaaccact ggtcgagcca
     1861 ctcgccgacg gtgaggctgc cacggagggc caggcccgcc ctcagacggc gtcgggtctc
     1921 ctcgatggcc gggagtgggg ccttctcgac cgcgacctcc tccagcatgt cgacgaggcg
     1981 ctgaagactg tccgggtcgt ccttctccgc cagggcgagc agggagcgga cgtggtcgag
     2041 gtcggcctgc gcgtccttga gggactcgta gccggcgcgg ctgaaggaac ggcgggtgcc
     2101 gtcttcgcgg ggcgggagtt cctggcgtat ggagtacgag ccgtgcttgc ggctggagag
     2161 cttggggcac ttcttgccga gcggcttatc ggtgtggggg tcgcggcagt agcagcggcg
     2221 gtgggtggaa cccttcaaag atcgttctcc tcggtggtgc tggggtcggt gtcaggtggg
     2281 tcgacatcag agagttccgg cggcaggtgc ggtggggtgc cgccgtcttc gcggatgaag
     2341 gcgcgggcgc tgcggagccg gtacttggct tccaacgctc tttctgcgta gtcggcttgg
     2401 gcgagtacgg cttcctcgcg ttctgcgtgg ttgggtgcgg tctcggcctt ccagcgctcg
     2461 tgcttctcgc ccttcagggc ggccagggcg gcgcgttggt ggcggacgtg ggcacggaag
     2521 gaacggagca tgtcgtcttc caagccgaag tcctcgctgt caccggtgaa ccagcgcatg
     2581 gcatcccagg tcggttcgga gtgctgaagg ggaaggcgct ggactcggtc gacgtagccg
     2641 acggggtaga gcaggcagat cgggtaggtc cgcagggctt cggcgaggac gatgacgtcg
     2701 accaggggca ggttggctcg gcggccggat tccatgttgg cgatcacgtt gcgcgggatc
     2761 gggtgcccga tctcctcaca gcggtccgcc aggtcctggg cgctcatccc tagctccttc
     2821 cttcgtctgc ggacttcggc ggccacggtg gccatcacct ggtccaccca ctccgggacg
     2881 tcgtcctcgt cccctccagc atcccaacca tgttgtgtca tgaagacaca ttaacttacc
     2941 taacgttgat tccatggcct ggagacgagc gcgattgccg tgttcgccga gggctcagtc
     3001 atggatggag cgcgtatgcg cgagaacgaa ctcaccggac gagtgaaagg catgagtcga
     3061 gaggagctgc tggagcttcc cgccgccgtt gacctggaga cgggtaatcg ggcgctgggg
     3121 ctcgggcgga gcaaggggta cgagctggcg aagcgcggcc agtacccgtg caaggtgctg
     3181 cggcttggca acgcctaccg ggtggtgacc gccgacctgc tggctctgct gggcctggcc
     3241 gcgtgagagc ggggagtcat agcagcccgt tctgcgctga gctgacacag aaacgctgga
     3301 ctgttgccgg gcgtcgacgt acggtccgtg ttccctcgcg atggcctggc gcccgcgaga
     3361 aaggggtgga cccccggcgg tgcaacgccg gaggcccgag caaccccgaa cggccctgga
     3421 agaaccaacc cggcggcaag ggcgtgcgag cccgccaccg ccagacgagg agctgccgag
     3481 tgcaacccga gaaccccgag tcctattccg ccccagccca ggctgtctgg cccgcagcgg
     3541 ccatccccgg ccgacccggc gcccacctgc gcgccgcgca ggctgacggc gccgatcctc
     3601 gccccagcgg tggtgcggac gcccggagtg ccgacgaggc ggaggcgccg agcggcctgg
     3661 aggagatacc cgatgcgggg ccgacccacg gctcgaagct gctggatgaa ctgcgtgcac
     3721 agatcgccca gttcgtgatc ccgccctcgc cggaggccct ggacgccatc accctgtggg
     3781 tggcggcgac gcacctacag cccgcgtggc agcacgcacc gcgcctggcg gtggtggggc
     3841 cggcgaagcg gtgcggcaag tcgcgtctcc tcgacgtgct gaccgagacg gtccacgaac
     3901 cgatgctcac catcaacacc acaccggcgg ccatcttccg gtcgatcacc gaggagaacc
     3961 cgccaacact cctggtggac gaggccgaca ccatcttcgg caccccgaag atggccgaga
     4021 agaacgagga gatgcgtggt ctgctcaacg ccggccacca gcgcaaccgg tacgtcaccc
     4081 gggtcgtcgg aaacgaccac accccgcacc gcttcgcgac gttcgccatg gcggccatcg
     4141 cagggatcgg ggacctgccc gacacggtca tggaccgggc catcgtgatc cgcatgcggc
     4201 gccgggccga gggcgagaag gtcaagccct tccggtcgcg gcgcgacatc ccggccttgc
     4261 acgagctccg cgaccgcatc catgcgtggg cccagccgct cctggatgag gccgcgaacc
     4321 tggagccaga catgccggtc gaggaccgtg ccgccgacac ctgggagcct ctggtgaccg
     4381 tcgccgacct ggccggtggg cgttggcccc ggctggcgcg ggtcgcctgt gcgcggatgg
     4441 tcgccgccga agaggcggcc gaggaggacc accccagcgg tgcccgtatc ctcgccgaca
     4501 tccgccgggt cttcgtcgcc cagcgcgagg tggacagcct gtccaccgag gaactcctcc
     4561 atcacctgcg ccaggacccc gaggccccgt gggcggaatg gggacgcggc gggctgaacg
     4621 cccgtgaact gggcaggatg ctcagcgcgt acgagatcaa gtccggcaac gtgcgcatgg
     4681 ccgaccggac ccagcgcaag ggctacatgc gcaacaagtt cctcgatgcc tggcgccggt
     4741 actgccccgc cgtccacccc gtcgacgccg acactactca cggcgaggac tgaggcccgc
     4801 ccccggttgc cgtacctgcc gtccctgccg tgatctcgca ggtcaaaggg catgcaggca
     4861 agacgggaac cggggccaag acggcaccgc gctccaccat tcgcagcccg ccgccaagac
     4921 ggtgcccgca tccgtcttgc gccgtccccc gccgtcctgc cgtatcaccg caggtcacag
     4981 ccctgcccac cgggacggaa ggcgtaacgc ctctgtcccg actcaggaca cggcccaccc
     5041 cgggcccgcc agacgccccg acgtcgtgtt ccgactcgga acacgacgtc ggcggcaccc
     5101 gccaggacgg agagccgagg cgttgccgta cctgctctga cctgcgcttg caacggccaa
     5161 gacggcaaag acgcaccaca ccactacccc aggagtaccc cgcttgagga tccctcgcat
     5221 gtcccgtcgc cgagaccgcc cgctgcggcg agaccagccc ggcctggagc agccggcgaa
     5281 gacgaagctg actgcggagc agtacgtgct ccgcacggcc ggcgtcgaca tcgtggccct
     5341 taccgccggt gcgttctggc tctcctacgc acacctggcg gacgtcgctg gccagcacgg
     5401 gctccgcgac tcgccgaccc gccgatgggc gtggcccgcg acgctggacg cgttcatcgt
     5461 cgcgggcgag ctgctcatgc tccgtgcggg cctgcgtcgc gtcaccgaca aatgggccat
     5521 cagcgtcacc gccatcggat cggtcggctc catcgggctc aacgtggccg gggtgacagg
     5581 cacgcgcgaa gtcggcagcg tgccgctgct cgactacgtg gtcgccgcgg ttcccccggc
     5641 cgccgcgatg gtggccttcg gcgtgctgat gcggcagatc cacgaactcg tcgcacagcc
     5701 tgctgtcgac cgttcggccc ccgattcagc gcaggtgccg caaccaccgt ccaccccatc
     5761 cgtccaccgc gccgaggcgc cgaccaccgt agtcggcccg tctgccgagg ttccggccga
     5821 gggcgtccgg cctgccgacc tactggttca gcccggtcgg accactgagc cgccgaccgc
     5881 cgcatccgtc cagccgccgg aatcgcccgc tgatgccgca gcaggcaagc cgcgcggtgg
     5941 ccgtccgccc ggcgccccgc ttgaggtact cgtggagatc ggccgggctg cagccgctga
     6001 gcagggcaag ctcacccgga cggtcgtccg aacggcagtt gaggacaaag ggctgacgat
     6061 cggcagcaag cggctgaccg acgtgatgga catcctccgg gccgaacccg aagccccagc
     6121 cgagaccgac cggcccgacg actgaccgga accgccgccg ggtgaccgga acccttccgg
     6181 tcacccggct cgccagccac cgccccgcgc aacgcgcgag cgtccacacc tgtggacgag
     6241 gcggcagccg ctcgagctcg atctgatctc tgcggtgacc cgcacgccct cccacctctt
     6301 ctccggagaa ccgtccatga cgcacgaccc gctccacccc gacgacacgc ccgacgagct
     6361 gccgatgctg acgaagtccc ctacgctgat ggaccgttgg cgccgcgcgt tcgggcgggc
     6421 tgccccgggc ggagccagta gtaccccgag tccgactcac ggccggtctt cgggagtctc
     6481 cgccccgggg gtggcggagg aggcccagcg ccagggggcg ccaggccagg atgtcgggac
     6541 cgagggcagc cccgacgagg acacgctccg caccgtccag cgcgagaccc tgcgccccgt
     6601 acgtgccacc gacaccgccg agagcgttgg cggtgagccc gtcgtgaaga gcgtccagcc
     6661 cacgatccgc cgtttcaccg gagacaaacg caaggagcgt gtcggccccc tgcgcttcac
     6721 gaccgatcag ctcggcctcc tccaggaggc cactgccgag cacggctaca agggcgaggg
     6781 cggcttcgcc gccgacgtcg tcgtcgcctt catcaccggc cggttcacag ccaacctgcc
     6841 cctgtccgag gaccgccgcc gcacccacca cttccgcgcc caggtcctgc gccagctcaa
     6901 ccggatcggc gtcaacgtca accagatcgc ccgcgccctc aacagcgacc acaccccaac
     6961 cgacatccgc cagcatctga ccgaactccg ccaactcctg gagctgatcg ccgaggccct
     7021 gcgccaaccc accgacccgg acacggaggc agccgcgtga tcgccgccat caaaccggcc
     7081 ggatccaaca cccgcggcct gctcgcctac ctatacggtc ccggcgacca cgacgagcac
     7141 ctcgaccccc acatcgtcgc cggattcgcc atgctcggca tgcccgaccc cggccgcgac
     7201 gagaacgcca ccctcaccga actcgcccgc tacctcgacc agcccgtgcg gctgcgcaac
     7261 agcgagttcg gcaagaaggc caccgaccac gtctggcact gccccgtgcg caccgccccc
     7321 gaggaccgct acctctccga caccgagtgg ggcgagatcg cccagcgcat cgtccaggcc
     7381 gccggcatcg cccctgccgg tgacgacctc gcctgccgtt ggatcgccgt gcgccacgcc
     7441 gatgaccaca tccacatcct ggccaccacc gttcgcgaag acggccggcg ccccaaactc
     7501 cacgacagcg gcatccgcgt cggcgatgcc tgccgcgaga tcgaaaagga ctacgggctc
     7561 aggcagctga agaagggcga ccgcaccggc gcccgccgcc ccacccaggc cgagatgcac
     7621 aaggccgaac gcctcggctg ggaacagccc agccctgcat ggctccagga ccgtatccgc
     7681 gccgccatcc cgcacgtgac caacgccgag gaattcatcg cctacctcga agccagcggc
     7741 gtcgaggtcc aggtccggcg cggcccgtca ggcgacctcc tcggctacgc cgccggccgc
     7801 cccggcgacg tcaacgaggc cggcgagcag atctaccacc ccggaagcaa gatctcccct
     7861 gacctctccc tgcccaagat cacgacccgc ctcgaatcca gccggcccga ggaacacccc
     7921 accgcccgcc gcaaccaccc cagcaccccc tggcagcagg cgaccgacgc cctcgacacc
     7981 ctccacaccg acctcgccga cgacacccac gcccaggccc acatcaccgc cctcggcgaa
     8041 ctgctcgaag ccaccgccca gagggcaccc gccaacctgc gcaccgaact ccaggccgcc
     8101 gccaaggcgt tcgcccgagc ccagcgctcc cagatccgag ctgaagaccg tgccgcccac
     8161 gccctgcgca gcgcggcccg cgacatcgtc cacaccgcca ccggccccga cggcagcgca
     8221 ctggcagcca tggtcgcagc cctcgtctgg gccgccatcg tcaccgcacg ctggcacgaa
     8281 gcgaagaacc acgcccacca ggctgacgcc gcccgccagg ccgtccagca cctccagatg
     8341 gccgccgacc gtgcccttgc tccgactctc gccgaactca cagcccgacc gcccagggag
     8401 caaacccgcc gcgttctcgc gaacgacgta cgagcagccg tccccgacca cgccgagcgc
     8461 atcctcgccg acccggcctg gccagcactt gccaccgtcc tcgccgacgc cgacgcccgc
     8521 ggccaccaac cccaccagct cctcaaggag gctgctgccc agcgcgagtt gaccagcgcc
     8581 cgccaacctg cccgggtgct gatcacccgt attcagcaca ccggccggaa ccctgccccg
     8641 aaccgccgcg ctgaagctgc ccgccgacgc tcgaccatca caccctcggt ccgcgtccag
     8701 cagatccaaa acggtcagac tccatcgacg actacgacgc ctgccgaaca gcagcaccga
     8761 cggcgccgtt agacaccgtc agagccgcag gggttgcgtt cctccgggat cggaggaacg
     8821 tgcgaggctt tcccggatca cgcgatcact ggcgcgcaga gccgccgtca gttctcctcg
     8881 cagctcgtcc gggagggccc ctgagccgag ggcgcaggcg cgcaccagcg cgcgacagtt
     8941 ctgcacttgc cggtccgtgg cgatctcggt gtacagaggg tgagccaaga tctcgcgggc
     9001 cgcatagccg tcttcggcgt ccgtcgtcct gcggtggagg tcctcgacga cgccgtgcgc
     9061 ggtgagcgcc tcggcggaac cgatcgcgtc aaggaccgta agtccgagcc gggtgtcgaa
     9121 gacgatcatc ccgggttcgg tcttccgtcc ggagtggacc gtcaccaggt ccgccaggtg
     9181 cccgtcgatc ggctgcccgg cgtcgcggcg gcataggacg gtcaggcatg tcgtgacggc
     9241 ttgttcccat gggtcgccgg gcatcgtgtc ggcaaggagg gcagcggccc acgcggtgtc
     9301 acccgcaacg agagcggcga ggacggcgac ctgccgaccg tcgagcatcc gctttccgat
     9361 gccatggtgg gcctcgatgt gcgccagcgc ttcggcccat cgtccctcgg tggtgagggt
     9421 gcgcgtgccg tctgcgagga ggacgcgcca cagccacgcg cgaacctcct ggcggtcttc
     9481 gccggtcgca gtgaggttcg cgggtacggt gacgtgctcg aaccgggcgg ctgcgcccgc
     9541 ctcgacggcc ttgtacaagt tgaggagtcg ctgccgactc tcatcggcgt gaccggcgcg
     9601 gatctggagg cgagcgaggt tgacgaccgg ttccagtcct cggatcgcgc tcatgccggg
     9661 cagggggcag gcatgaaggt aggcggcggc gtgctggtgg cacatctcgc gggcgaggtc
     9721 ggggaggtcg aggtcggagg cgatgagcgc ggcctggttg taggcggccg atgcgagccc
     9781 ctggtcagtc tctttcaccg cggtgtcggc caggtcgacg agtgcgcgta cgcgttcagg
     9841 caggggcagg caggcgggtc ggaatcgggc gacgagcggg aagcgctggg ctgtggagcc
     9901 gtgtgggtcc atggatcccc cttgtcgaag gtgaggaatg ctgaggcggc ggtgcccgcc
     9961 agccacgtgt cgacgggcac cgtccgctac gcgtggggcc tcactgccag tcgacgacga
    10021 tgcggttcag cggggtctcg agagcgaaga ggccggggcg ccgctcgatg ctgggggcgt
    10081 cgaggggctg gatttcgaac gtggcttcgc ggctgcggta ttcgcggtcc caggtgcgga
    10141 tggcgtcggc gaccttcgcg gtcagttcgt cgctgccggg accgtggccg atgacgccga
    10201 actcccagag cttgccgccc tcgggggtcc tcttctccga cagccgccgc gccaggtagg
    10261 tgacggcgcc cttgtcgacg acggcggtcg acgaggggta gggatcctcg gtgagcagag
    10321 tgcccttggt gctctgaggg aacagcatcc ggatcaggcc ggaagggagg gagcaggtga
    10381 cgaacagctc catccactcc ggtgactcca tggcgcggac cgtcatgccg gtccactcct
    10441 cggtgcgcgg ctggtcgagt acgcctgcga gggcttcggc gtcgatgttg agcccggcgg
    10501 gggcctgaag gcgtacggcg ccgtcggtgc tgagcgggat cactcggcgg tcgtcgtcgg
    10561 cgatgccgcg ccgaagcggc atgaaggtgt tcatctcgct gccgagggac atccatcggc
    10621 cgtcgcgcag ctcgtaggtg atggagcggg acaccgtgcc cttgagacgc tgggggacga
    10681 ggagccggcc gccgggtgcg agctgctgca gccaggcgtg cggtacgccg tgcgcgccga
    10741 cggtggcgat gatccggtcg tacggcgctg cttcgacgta gccgagcgcc ccgtcgcggg
    10801 tcacggcctg gacgttggtg atcccggcgg cggcgaggtg cgcgcgggcg ccttccacga
    10861 ggtcgtcgtc gacgtcgagg gtggtcacgt gtccgttctc gctgaccagg tgggcgagca
    10921 gaccggcgtt gtagccagtg ccggcgccga gttcgaggat gcgctcgccg ggctgggctt
    10981 cgagctggtc aagcatgagg gcgacgacgc ccggctggga ggcgcaggag atggacgtgc
    11041 cgtcggtgtc gtacttgatg tgcacgggtg cgttggcgta ggcgtcttcg agtgacgcgt
    11101 cgggcacgaa cacgtggcgg ggtacggtcc gcaacgcggt ctcgacggcg ggcgtgcggg
    11161 cgtgtccgtc cgcgcggagc tggtcgacaa gggcgttgcg gaggcgctcg gcgtccgccg
    11221 tgggagtggt gatcgtgtcg gtgttcaccg agccgacgct atcggcgtcg gccgttgcct
    11281 cggtggacgg ttcggtgtgg tcactcgttc ccatgactac ctctcgtgcg atgtgggaca
    11341 gggcgctctg gtcgtcccgt aggagaccgg cgcggttggc gtggaagatc acgtggtggg
    11401 cgatgacggc tcgcaggccg cgggtgaggg cgccgcggcc tgcgaggtct gcgagcgtgg
    11461 cgccggcccg ttcaaaggcg gtcacccatt cctcgtgagc gtggagtggg ccatccgggc
    11521 ggcagaggcc gtgggcgtcg gcggtcatga gcttgcgcat ggccggagcc agtgcagcgg
    11581 ctcgttcggg cggttgtgga gcggtggccg gtcgaagggc cgcgaccttc gcccatacgt
    11641 cgccctgctc gaaccagtcg agtccagcac cgcgcatcat gacgcttgcc aacaggacgg
    11701 cggtctcccg gcgtcccagg cgcatcgggc tcggctggta ggtgagcagg tggcgggaat
    11761 cgctgtggaa cagttcgtgg gctgtgtcca tggcctccgg gccgccgaac gtgtcagtct
    11821 cgggctcgta gatgcagggc aggcacgacg cggccacgcc gtcgccgatg agatcgctca
    11881 ggagcgactc gatggctggt gagggcttgt ccgcgaggta acgcagcggc cagggctgct
    11941 tgttcatgaa ccaccagtcg gtgagctgcc cgtcggcctc cgcctcgatc agggtggggc
    12001 cgaagcgttc ggcgatggtg cgctgggcaa tatcgcggtc gacgaaggtg atgttgtgct
    12061 gctgccagcg gtcaggaggc attgaggtcc ttcggtcggt ggatcaggcg ataaggaggc
    12121 atgtgtccca gggggaccgg ggtggtgcgg cggtgctggg cgcgaggagg gccagggcta
    12181 tgccggcggc gccgtcgagg aagccggggc cgctttcctc gtcctggatg aacgccgtgg
    12241 ccgtgagttc ggggtcggtg cccggtggga tgaccgcagc caggagggcc gggatcgcgg
    12301 cgcggagttt ctccccggtc gaggggcggg cgtcgtcggc cgtacgcgcg gcgacgtgag
    12361 ccaggccgga gaagccgtgg cagaggccgt tgtccgtcgt ggccttcagc tgctcggggt
    12421 cggtgagggc ggtcacgagt gcgttctccg cgtcgatctg gcggcgggtg tcgccgaggg
    12481 cgagcgcggc aagttgctgg gcgcgggcga ggccggcggt gccgtagcac caggatggcc
    12541 gccggggcgc ggagggggcg agatgcccgc ttcgcagctc tccctgagtg acccagtacg
    12601 gccagaccgg tccgccgtca gcctcctcct tccagcggtc cagccaggcc aggatggtgt
    12661 gcagtgctgc gtggtgccca tcggtgacgg agccgttccg agcggcaagg gccaggagcg
    12721 cgagaacgcc gccgatgccg tgcgccatac cggtgttggc gtgcccgccg gggaatcggt
    12781 cgtccgggct gcccgagggc ccggtccccg cccaccagcc cggaagggtc tcgccgtggt
    12841 gggtgatcgg ttcggtcagg cgcacgcagt agtcgagaac ggcgcgcgtc gtggagctgc
    12901 cggggcttcg gcgcagtagg taggcgccgt atccggtgag gccccggata gcgtcgaact
    12961 cagcgagctg tggcaggcgt ccggcgtcga tgcggcggtg tgcggcgtcg agacggcgtc
    13021 cgacgtcgac cgcgatctgg gcgtccatcg cgtcgagggc gcgctggtag gagccgggaa
    13081 ggtggtcggc ggcacaggac agggcgtggg cgaaggcagg cactccgtag aacgggtggc
    13141 tgtctgggcc gctggtgagc ggctgccggg aggcggcggc gagccagtcg tgggcgcggt
    13201 gccacgggct gaggccgttc gcggccagct cgatgtgcag gagcgcgatg ccgggtggcc
    13261 cgtaagcgag atgctgccgg tccgagcaca gcgtcctgga gccgtgaggc atggtctcgg
    13321 ggtcggcgag ccgggcggcg atggcgtcga ccaggccgag cggagggtgg gcggtcacga
    13381 ggccctccca cgggggcggg cggtccaggc cagggcggcg gcgcgcgcca ggtagaggca
    13441 cacctcttcc tccgggaagt tcacggcgac gtggcgtacg aagtggacgt gcagcaggga
    13501 ggtcaggacg tcgtcgacgg cgatgccctg ggtgtccggg ccgggcaggt gtggccggta
    13561 cgtggcgagt gccgcttccc ggtcgaccca tccggacacg atggcgtctc cgcccgggac
    13621 actgcgcaag gccgaccagt cgtcgctcgg gtcggcgagc cgtacggcct cggtgaactg
    13681 cgggcgcgga acgggcatgg ttgcggtcgg cgagacacgg tcgatcagcc accgcatccc
    13741 ggcctcggtg gtgccgagga aggcggaggc gatggcgacc gtgtgggccg ccaccagcgt
    13801 gcgctgactg gggcgctgtg gctgcgcgag ctgggccagg acggcgcgcg agtccgcccg
    13861 gaacacctcc tcggccgcct cccatgcggc gccggagccc cagcggccca tctcgcggta
    13921 ggaggtggga tagcgcagat cggccagcag gccgatgctt cgtagctcgt cggcccaggc
    13981 gctcaccgtt cgggccgtgt cggcgaaggc ttgcgcgtcg ggtagggcga tgcgtacgcg
    14041 gaggtgttgg tccgggtcgc ggaagcggat gaaccaccac gacgggttgc caagccgttc
    14101 gaggaggccg ggcaagtgct gggagaccaa gacgtcttgg cggcgggggg cgccgtacag
    14161 ggcggccaga aggactgagg aagcggcagg cgtctgcatc tgggtcgaag acagggcacg
    14221 gccccggctg ggggccggca gtggcggcca taccgacggc ccggttgctt tgaggggcac
    14281 cacgacctcg tgggctcgcc cgccgcacca gccatacgcc tctcgttccg gggcctcgac
    14341 gagtacggcc aggcgcgaat ggtcgaggtg ccgacgcagg agtgcacggt ggccggcctc
    14401 gtcgaggtcg aggaaaaggc gccggtcgtc ctctacgagg taaacggggc gcggcagcct
    14461 ccgccgggca cgccagttgc tgagcgcggc gtcccactcg gtccgagggc gggcatggcc
    14521 gggcagttcg gacgcttcca gccgccagcg cgccggggcc agcacggtcc ggccgtaccg
    14581 cacacgtgga aggaacggca tcgccgctgc ggcgccccag tcgaagacgg tgacctgcgc
    14641 gcactgggcg cgggacagtt cggtgaggaa ccgcaccagc ggcggggtgt gggtgcgcag
    14701 gttcagcgcg tgcatcccga cggcctcaac gcggtggcct cgctcgggga cggcgaggta
    14761 catgcggcgg ccgtcgcacc ccacagccaa gtcctccggg gtcaggacgg tgtcttgcgg
    14821 gacgcggtgc tcctgaaggc tgatcacggc gggtagaacc tgtggggagc gggtgacgtg
    14881 ggcgctctcg gagagcagcg gcgggaaaga cagctgcgcg gggacggtgt tgccgtctgc
    14941 ggccgggagg tcggcaagct ctgtgaccag ggcctcccgg tcggcggggg ccagcacgct
    15001 gaggaaccgg cccatggaga cgccggcacc acgggacaca ctcacgacct cgagccggaa
    15061 ccgcccacgc tgcaactcct ccaggctggc cgcatacacc cgcaccccga tctccaagtg
    15121 cggcggcagc cgaggctcgt caggacccac gtccagggcc tcaatctgtt cgtccgtgag
    15181 gatcacttcg tcacggccgt cgagcgcggc ggcctgggcc agccgtacga ggacgtcatc
    15241 ccgagcggag acgcggggcc tgcgtgggct ggccggagcg cctgggtagc cgtcgggata
    15301 gccggtgccg ctgtccgcga cgacctccgc gagcggcacc atcgtgccga tgccgtaccg
    15361 ctcgtagaac cgctggtggt actcgttcca ggcggcggtc ccgtacgggc ggctgctcaa
    15421 gcgggtcagg acaagaacgg cgcgctcgac ctcgcgggcg accgcttccg gcagaacgat
    15481 ctgtgcgttc aggcggaggt cgagcgcgac ggggtggcgg cgcaggcccg ggatgaggtc
    15541 tcgcatccgc gccgcgacgc tgtcccggct gccgtgcgtg gtgcactcct ccaggcccgc
    15601 ccggaccgcg tggagttcgc gtacggtctc cgcgaccggg gcgaggcttc cagcgtcgat
    15661 cacgtcgagc tggctcacca gatacccgag ggcatcggtc tcggtgctcg gagcgtgcag
    15721 gcccgtgatc agcacccgcc gccggatcag ctccgccagc agttgacccg ccttctcggg
    15781 accggcctcg gggaactccg cctggagctt ttccacgagg gtgccgaacc ggatcggtag
    15841 tcggcccgcg gcaaggacgg cgcgcaccgg ttcggtcagg gccaaggacg cctcgaccgc
    15901 gcgagtccgg tcgtcctgga cgtcgggctg gaacggcacg acgagccggt ctccccggta
    15961 cgtcacggtg tggttgacga caacgggtag ccgttcgagg aggtctgggc acgactccag
    16021 ccgttcaacc acggcagcca gccactctgc ccccgcgcgg ccgacggcca cgtgctcctc
    16081 gctccagtcg gcccgggcct gcgggccgaa ctcggcggtg gccacgccgg cgaacaggcc
    16141 gaagggtgtc gcccggtgct gggcccgcag gaggtagcgg gccacggaca tcgctgcgcg
    16201 ctgcacatca cggagcgcgg gatgctcagc cgtgcacagg gcccgtacct gcgtggccag
    16261 gacagggctg gagtgccgga gcgcctcggc gacgtccttg ttcgcccaga ccgcgcgtag
    16321 ccacgccacg cgggcagatg aaccgcaggg tgaacggtca tcgaggtcag ggcatggcgg
    16381 gaacggcagc gagggccggg ccacggcgcg cacgagagcg gtggaaccgg tgcggaacgc
    16441 tgcaggcgaa gcaaccacca agtacctccg taagcgaggg ggcgggcggc tggtgccgcc
    16501 gcgcggagac gcggcggcac caggccgggg tgacctgggg cgcgcccagg tcaggcgacg
    16561 ttggtggtgc aggcgccgca ggtggacccg cagttgtcgt cggtcaggtt gaccaagccc
    16621 gccgggtcgg caatctcgac gagggagacg tccaggtcga agccgtcgga tgccccaggg
    16681 atgtgcgggc gtacttcggt gcggctggga actacggtgc tgcgcgtcat gcttcaactc
    16741 ctcgtaatcg ttgtggtgtt actgggctgg agcgcccacc aggtgccgtc acgggagcgt
    16801 tgccagacgg ctgctcaccg gacggcgcct ggccgcccag cacgagggga cgtgctccgc
    16861 gtaggaaagt ccttgcgggc tgcctgcctc acgccgggaa gtcatgtgcc gggattctga
    16921 tcaagcggat gccggtcgcc gctccatgaa gtaggcgagc gcctgagcct tgaggcgatc
    16981 gaggcacggc tcgcacgtgt agaagggagc gtgctgcccg tcccactgca ccgggccgag
    17041 ccagatcacc aggacgccgg tacgcccgca gccgagccag cagtcgccgg tgatccacgg
    17101 ccactccatg gaggaacgtc ccctttctca gctggtcggg atggtcgatc tggcggcctg
    17161 gcagttggga acgcaggccc agagctggaa cggcacgccc ctgtggcgta tctcgcccag
    17221 ccgtcgtcgc tcgctcccaa cggccaggcg cagagggcgc agtccacggc catctgctgg
    17281 cggggccgga gtcgtgccag atccgaaagg ggcgaggatg ccgtggccgg gatgctcact
    17341 tgccaccctc ggtacggagt tccgcccaga cctctttgcc ccaagggcgc ctgtccgagc
    17401 cgtgcaggtc gtagccccag cggtcggcga cagcatcgac gaggagcagc ccgcgccccg
    17461 actcgtcgtc gtcagccgcc tggctgagta tgggaagacg cgatggttcc cggtccagga
    17521 ccccgacacg cagtcgagtc gcgctcggcc gcctaaccat gaggcgaatc tcgggacacg
    17581 gagtgtgcct ggaggcgttc gcgatgagct ccgtgatgat cagggcggca cggtcggcga
    17641 ggccatcgag gtgccacacg ccgaggacgt cccgaacgag atcgcggccg agctcggccg
    17701 tggacggctc gcacgggaag gtctggctgt acgtgggatg gccgacgggg agggcctcaa
    17761 ctggtgttct cagactcgtc attggggtgg agccttcgtg tcgtctcggc gcccggcccg
    17821 cccccgcggg ggaacctcag gggcgggccg ggccgtcaac agccacccgc acggtggggc
    17881 gcggcgggcg accagcaccc agacaactcc cttcaccagc aggctggtta ggacgttcag
    17941 gcactcagcc gacggaccgg cctagggcgt tttgacctct cctttacctg gcgggcaggg
    18001 atcgcgcggg ctaccgtgcc cgcatggaca ccacccgcaa caccgttctt gaggcgtgga
    18061 tgaccgaaca cggctacagc tccaacagcc tcgccgaggc cgtgaacagg gccattgaac
    18121 ggttgaccgg gcgccctggt ggactcgacg gctcatcggt ccgggcatgg aaagcgggcc
    18181 gggtgacctg gccaaagtca gctgcccgca aggcacttga agacgtcacc gggctacccg
    18241 ccgtcgcttt agggttcgtg ccacggggcc ggccgtcgtc caccccggcc ccaccgcagc
    18301 aggaggaccc cgacatgaag cgccgcaccc ttgtcggcag catcgcggcg gctgccgccg
    18361 cagcagccgc acctggcacc gcatcgccgc gccgtatcgg tatgagcgac gtcaaccgcc
    18421 tcaacaagcg cttcgccgag atcatcgcca gcgaccaccg ccacggcgga caactcggca
    18481 tcgaacagcg ggccgccgcc ctcgccgacg aggcactcaa cctccagaac gccggcagcg
    18541 ccacccagcg cgtacgaagc aacctctacg cctcagcagc tgccttccgc tcctccgcaa
    18601 tgtgggccgc catcgacggc cggcgctacg acgtcgccaa ggcgcacatg cgcgaagccc
    18661 aggccctcgc cgagatgtcc ggcgaccagg cgatcaagtt ccgcatctgg agccacgcgg
    18721 gcaccatgta ccgccacatg ggccgccccg ccgacgcgtt cgccgccaac gacgtcgccc
    18781 gcaacctgca cctcacccgc cgggaccccc tgttcgcctc cctcggcctg gcccgccagg
    18841 gcgccatcca cggcacggca caggaccgca ccggcacgcg ccgggccttc gagcaggcgc
    18901 aggacgccat gctgcgcgcc gaccctgccg actaccggcc ggtgtggatg ctcgccttct
    18961 acgaccaggc cgaactggac tccctggccc tctccgcaca cttggcgctc ggcgactact
    19021 cgaccgccga ataccacgcc caccgctgcc tgtccgccct ccggccccac atgatccgtt
    19081 cccgcgccat caccaccacc cggctcgccc acgcccagct cgcccagggc gcccccgacg
    19141 ccgccacggc caccgcgatg aaggtccccg ccgaagccgc tacccagcac gcccgggtca
    19201 cgcgcatgct gcaggagttc ggggccgcac tgcgcgccac cgcgccgggc agctccagcg
    19261 tgcagacctg gaccgagcac gctgccgcct ggaggatggc tgcatgacca cggcgcccgc
    19321 catcgaactg cgcaccttca ccaccctcga caccgcccgc ggcgacctcc tcgacgtgta
    19381 cgccgacgta cgcgccccac tcctccacct gccgaactac gcggtcaccg cgttcggcga
    19441 acgcctggac cgacacggca ccgagccggg gttcacggcc gtcctcgcgt acgcggaagg
    19501 gcatccggtc ggctacgcct acggcaacac catcgagcac ggcgaccgct actggcagcg
    19561 caccagcccg acgccggccg agaagtacac cgagcgcccg gccgtagccc tgaaggagat
    19621 cggcgtccgt ccgacctggc ggaagaccgg gaccgcccgt cgtatccatg acaccctcct
    19681 cgccacacgg gacgagccgt acgtgacgct catggtcaac tcgaccgccg gggatggaaa
    19741 ggtccacgcg ctctacctgt cgtgggggta cgaggacatc gggcagagcc aaccgtcacc
    19801 ggcctcaccg gtcctcacgg tgatgatccg taccattcgc tgatcggctc ccgacgtctc
    19861 cattcgtcac agggccgatc gcagtagatc ttgaccgtca gttcgggatc gcttcccgtt
    19921 cctcgggccc ttggcagctg atctggggga caatgaacca ggtctgctag tagcgcgcat
    19981 tgcgtgcccg atccatccgg agcgcgtcat ttctgttcgc gaatcacgag ccggggatga
    20041 tttccacctt ctatgggcgg cccggcgcgc attgcagctc ctgctccccc gaactgacct
    20101 gaagattctg cgactggagg ggctatcccc agctgacgca gccgaagaag atgatcgcta
    20161 cttgggctgc gacctgagtg aatactacgg cggagagacc ttcacgacag cgaatcgcct
    20221 ggttttggct cagctgaaat acagcgtcaa gcactcaggc cgagcctgga cggcggccag
    20281 actgtgccag gtcaagacca ctggtggtac gcctccgctt cgccgcctgg cagacatgtt
    20341 cagcgggctg gtagaagact gggatgcgtc gaccgtagta agcaaggtca atatcgcact
    20401 ggtgagtaac cagccagccg acgccgatct cctcaacgcg ctgaaatcgg cccaggcagc
    20461 gctggcggac cgaccgctgg gtgtgcacgc aggacgtgcc tttgcttcac tggtcaattc
    20521 tcaccagcag atcttggcca aactgcgttc agcgtccggg ctgaagagtg gtcattttac
    20581 tgattttgtt cgggtattgg acctttctgg ctgcggcgct gacagtcggg cgctgcagac
    20641 gctgacactc caccaggagg catccgcctt ccttgtcggc tcggcccgtc ctggagtcat
    20701 cgggctgata gagctcatgc gccagcagat gctcccagaa acagcgggtg accctgggct
    20761 gagtcgcgct gacatcatcg ttgctttggg tgcaagcggg gaacgatcgc tatttcccta
    20821 tcctgcactt gtggcgaagc ccaaagagct tgtaccaacg gcccagccgc ggagcctggc
    20881 cgcagctgta acggctgcac cggccggaaa gcttctggcg cacggtgggc cgggtgtcgg
    20941 caagacaacc gtcctgactg cgttggaagc cgaactgcca ccgggatcga tcctcgttgc
    21001 gtacgactgc tacggcgacg gccagtacct caatccagcc aacgaccggc acagcgaacg
    21061 ggccgttgtc cagatcgcaa acgacgtcgc ggttcggggc ggcgctctgc ccgttgtggt
    21121 gcccgatgga ccagtcgtcc acagtgagct ttggcgaggt cttgagggaa cgctcaccgt
    21181 ggtagcagac gcgctaccag agtccgccct cctcgttgtc gcagtcgatg ctgctgataa
    21241 cgccgttttc gcggcgcacc gtagtggagc tgaaccgttc gtgcgtgggc tatggcacat
    21301 gcaactgcca cctaacgtgc gggtactgat gactgcacgc agcgctcgtc gcgcggacgt
    21361 cttggctgga gctgaagaga caggtatcac cgagacagca cttggcgctt tcgatgcctc
    21421 ggccagcgcc gcgatgttgc gttcgatgta tccgaacgca acggagaacc aatgcgcggc
    21481 cttccacgcc gccagtaacg gagtggcacg cgttcagaca tacgcactcg gcgctgggga
    21541 gcagtcgcaa ggcacaggcg aaaccccggc catgctggat atcgaggacg tactcgtacg
    21601 cgcggaagcc ggcctggcag ccatcttcga cgaggtccta gatagcgcct tctccaccgt
    21661 ccatgaccgc gacgtgcggc agcagcacat gggcatcctt gccgccatgg cccgccctgc
    21721 gcggccctcg acactcgccc gggtactgaa gatcaacgaa ggccgcgtgc ggcagctgtg
    21781 cgacgacttg tttccggcgc tgcgaatctc cgacggtgcc gtcggctttg ccgacgagga
    21841 cttcgagaat cacttgcgtc aaaagttgtc agtgtccgat gtacgccagg cccacgatct
    21901 ctttgctcag gacttccttc accaccgcca tgtcgacgag gaagcagcac gactggttgg
    21961 tgagcacctt ttcaactccg gccgccacga agaactgctc acgatggcac ttgatgaagg
    22021 cgcgccagag gcgatcacag acggcatagc acgtgcccaa gctctacgag tccggctcac
    22081 gctggcgcta cgcgcggtca tggagcgcaa tgacaacaag gtatccggag atgcggttcg
    22141 cctcctgctg gctgcagggg acgcagcccg caccgattcc agcctcgttg acacggtgcg
    22201 tcagcggccg gaactcgcat tgctccacgc agatgcaagc acagtcgccg agatcttgtt
    22261 gcgagaagaa tcgggaactt ggcgaggccg cgctcacctc cgggccgcag ccatgcttgc
    22321 atggctgaac ggacgtacgg cagaggccgt cgagcaactc gaccttgcct acgcgtggct
    22381 acgggcctgg tcgcggcagg acgcgggctg ggatctgagc gcagaggaca tcgcctacgg
    22441 cgtacacgcg gcatacgtgc tgcgtgacct aaatgccgcc tatcgcctgg cggctggctg
    22501 gaatccaccc caattcgttg acaaggtaac gtggcacgtg gctcagcatg cacctgcaca
    22561 tgtgcccgta aagcaggcaa ttcaggatct aaatcaggta cgagccagcg catggacgca
    22621 ggctcagttc gcagttgcct atggacgggc cggggaaagt ctgcccgtca ggtgggtacg
    22681 gcagcttgcg acccggttgg accggctgcc gctgcgcccg gtgagccgtc cagtcgagtg
    22741 gggtatgtcg ttctgtgaga tcgcgctggc gcatggtgtc gccaaaacca aggtgcgacg
    22801 tctaatccag cgttttgcgc cgtcagtacc gtctcacctc aacagttaca ccggtagcag
    22861 cgagatgctt agtccgttga aggcggcatg cctggaagcc gccatccgcg gctccaaaat
    22921 cacagctgaa cagctactcc cagaggattt gcggccacct aacgataata ggcgcagtta
    22981 cgacaagaat gagtccacgc gtcggctttt cctgcagatt gccaatgact tgcttcctgt
    23041 agtaactgca caggccgaat gtgtggcagt tgccactgat cgtcaatcct gcgctgacga
    23101 tgtcgagctg gcaactgcag aagtcgtaca ggtcgtgcgc ggccggctag aggcccaagg
    23161 ctcagaacat agattcgacc aacccggtaa tcgccaacgc gtctggttca tggctgcggt
    23221 cgaggcattg gtatcagctg cacgagccat ggacgcgttc acccgaaaag gcagcggcca
    23281 ccacagcgat caaccctcga caaatgccat gaagatgcag atcgaaaatc tgttggcaga
    23341 cgtaggggac agcatcggac agctgttggc cgacgggtcg gcatacgcgt gggtgcaaat
    23401 gagccgtatc ctccttgaaa atgaggtcgc ccgagaagtt gcgcttcagc tacttcagca
    23461 ggtgggtgac gtcatggatg gggcgacgct cccggcaaca gaacggcggg acgtactcct
    23521 ggacgcagcg gcggcagcgc aacacgctga cgcagctctg gccgcggacc tgttcgctgc
    23581 cgcagtagac gccgccagcg gcgtggacgt ggatgtcgcc ctgaggctac gggctctgct
    23641 cacgatcgcc gaccggatcc ccgatcgggc aacagacgct acaaccggcg gagatcgtgc
    23701 acacatcgcc cgtcggctcg cccacgcagt tgaagacgcc acccccttcg tgccggagcc
    23761 tcgggaacaa ctgccacacc ggctcgctct cagcgtggcg agccgacttc acgggccgtc
    23821 tggtctagct ctcgcctgcc ggtgggagga cgacggacac gtgggtctgt ctgaaggcat
    23881 tggcacagtc attcctctcc tcgtcgagac aggaacagtc ggcggcttta aggctttctg
    23941 gatgctgcgg cttctcagtc aacactccga tgtggtaacc cctgcggtca ctgtcatcag
    24001 atgcctcctc aaccagggac cagcgggtcg cagccaggcc gtcacgtgcc tcgaaacgct
    24061 aaccgactgg gtcgttcgcg acctaccacc gaaccaacaa cctgacgctg cccgtaatct
    24121 caatgctgcc attcaggaaa tggggctggg tcagattcag gccgcgcagc ggttgcagtc
    24181 ccgcgcacag gcactttccg ctctaactgc aaatagggaa gtcatccgct cttcacggga
    24241 ctggggagga ttcagtgaag agcgaacagt ggacattact agcctagtca atgcggcgag
    24301 tttcacccga gccgatcagg atctccccga acttgtcgcc cgttatgcct ctgatgaacg
    24361 cgtagtcacc tacctgacta ctgcggctca tcgcgctggc ccgtcggggc gtactatggc
    24421 gctggaggag ctcctaagac tcgccgatcg tggagtgcgg ggcgcccgcg caacccaggt
    24481 agcacgcgta gtgagcgggc tatgctacga atggcgtgcg agcgcgagcg tgcgcgactg
    24541 gactagccag cacctgccga tgtgggtatc gcgacatctg ctcgacctat tcaccaccgg
    24601 actagatcgg catggcaact acggcctatt gctacaattg ccgagtaacg cccctggatg
    24661 gtcaaattgg ctccttccgg cagcatctgc tcaccttgat gagttgactg ccaaccagct
    24721 ctacacgctg gcagcatcac tggcagaaac gctgccggcc acatcaacac tttcgcaaat
    24781 catcgaatgg gctttgaatt cccgtccgtc tctacccaac gctgccgcta tcacacggct
    24841 tcccgctact tcggcgatca gtaattctgc agctgacgtc aaggccgccc gcgagacctt
    24901 gcctgaacca cctgaggacc cgagcgcgct ttttgcagcg gcattgtggg ccctgctcgg
    24961 ccatgccgac cggcgtgtgc gatggcgagc tgcacacacg gcacgaatta tcctgactcg
    25021 aagcagcgac ggcagcgctg tggctgacgc gctctggcgc tgcgcaacgg aatcccccac
    25081 tggcggtagt ttccgctccg ccacgcttga attctttccg ctttcagctc aacagtggct
    25141 gctcatcgtc tttgcgcggg tagccagaga agtcccagtg gtcctagtgc cgctggccac
    25201 tgagctagcc gcaatggcag tagaccgaag tcagccccat gcagctattc gcgagttggc
    25261 acgccaagcg gcactcgacg tggccgcagc ccatcctgat gcgctacctg cgcacgttgt
    25321 cagcgacctc gcgttcgcga atcggcctcg gttgtgcagc acctcacgcg aggtacggaa
    25381 cgttggatcg cggtatggcg actacggcac gcgcttccac ttcgactcta tggacgtcgt
    25441 accgtactgg tactcccctc tggcagaggc tttcgacgga gtgtttctcg ccgacgtcat
    25501 gcagagtgca gacaagtgga tcagcgagcg gtggggccgg agctcagagg aaacgcggcg
    25561 ggatcccagg gttccccaac acgagcggtc gtgggcgctg atcagtgctg accatggttc
    25621 cttgccaatc gtggaaacgc tccagaaata cctggagtac cacgcgctcc acatggtggc
    25681 tggcgagctt gtcgacgggg aaaaccccgt gctcaggcac tggcgggaca acgacgagtg
    25741 gacgggctgg ctgaccggtc atcttcctca ctcatcaacc cactggctgg cagatatccg
    25801 cgaaccagtt ccggctcgct cgctcacgct cggtatgtgg gatcggctgc agctagacaa
    25861 cgccattacc tcagagcaga cggcgacgtc tcagcatggt tccacgtctg ctgttgatcc
    25921 ggatccagca gcgcggaggg gattcgacgg agccgctgta gcgcgacagg catgccgcga
    25981 actggacatg ctcgatgacg atcccgaaat gatcgtagtg tctgcatccg tcaccaccta
    26041 ttctgaccgc cattcgtgta cggcctggtt gaccagcgct ctagtaaccc cagaagccag
    26101 tactgcccta ctcgctgctc tggcgagcag cgcacgtccg cagggcctgc ctggggtcgg
    26161 cgaggggccg ccatggggag acgaaataga tgaacccaag ctgcaactgc tcggctggat
    26221 cgtttatcgc gagtcagacg acggcggcct agaccgcgac gacccgctga cgggtggcat
    26281 cactacctct cgacgctcac ttttcacaga cttcttcact tgggctcgt
//
