LOCUS       NZ_CP104794            24726 bp    DNA     linear   CON 09-JUL-2024
DEFINITION  Streptomyces sp. FZ201 chromosome, complete genome.
ACCESSION   NZ_CP104794
VERSION     NZ_CP104794.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. FZ201
  ORGANISM  Streptomyces sp. FZ201
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8604396)
  AUTHORS   Zhang,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2022) College of Life Science and Technology,
            Jinan University, Guangzhou, Guangzhou, Guangdong 510632, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2021
            Assembly Method                   :: unicycler v. 3.14.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 235.1x
            Sequencing Technology             :: Illumina NovaSeq6000; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025402955.1-RS_2024_07_09
            Annotation Date                   :: 07/09/2024 06:54:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,562
            CDSs (total)                      :: 7,471
            Genes (coding)                    :: 7,336
            CDSs (with protein)               :: 7,336
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 55 of 135
            Pseudo Genes (incomplete)         :: 92 of 135
            Pseudo Genes (internal stop)      :: 7 of 135
            Pseudo Genes (multiple problems)  :: 18 of 135
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:45:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 466281
            Orig. end                         :: 491007
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP104794.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zhang Fei, College of Life
            Science and Technology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24726
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /product="melanin"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /rules="melC"
                     /tool="antismash"
     cand_cluster    1..24726
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /detection_rules="melC"
                     /kind="neighbouring"
                     /product="terpene-precursor"
                     /product="melanin"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..21026
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21026
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11026](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11026
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            535..1977
                     /locus_tag="N6J21_RS02115"
     CDS             535..1977
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126225.1"
                     /locus_tag="N6J21_RS02115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_261720557.1"
                     /transl_table=11
                     /translation="MPCSPAEISSLFLFEKLAPEQLGRLCAEGRVERFEPGPVYTEGDP
                     ATCFYVMIEGTVVLSRRVGGDDVEVIRSSQRGVYSGAMQAYLGDRARQVYNNSMRVTEP
                     TRFFVLPADTFAAVMQEWFPMAVHLLEGLFFGAKNTQQVIGQRERLLALGSLSAGLTHE
                     LNNPAAAAVRATATLRERVAKMRHKLAMIASGPYPREQLAGLIEIQERTAELVGKAPAL
                     SPLEASDREDTLTDWLDDHGIPDGWRLAPTFVQAGLDIDWLEQVAAAVPEEVLPGAVGW
                     LNYTVETELLMSEIEDSTTRVSHLVDAAKQYSQLDRAPFRTVDVHELLDSTLMMLAGKI
                     GPRIKVVKEYDRTLPEIPAYPAELNQVWTNLVDNAVAAINSAGGEGTLTVRTATDHDRL
                     LVEFRDTGTGIPPEIRGRIFDPFFTTKPVGEGTGLGLDISWRIVVNKHHGTLQVESEPG
                     DTRFQVLLPLTAADHENPEESP"
     gene            1974..2324
                     /locus_tag="N6J21_RS02120"
     CDS             1974..2324
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662987.1"
                     /locus_tag="N6J21_RS02120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_261717452.1"
                     /transl_table=11
                     /translation="MTDGIDPSVPPSGTGCAECDEVGGWWFHLRRCAQCGHIGCCDSSP
                     GKHATAHFRATGHPIVQSFEPGEGWFWDYGASDLYESGPELAPPASHPADQPAPGPAGR
                     VPGNWAQVLRGA"
     gene            2363..5296
                     /locus_tag="N6J21_RS02125"
     CDS             2363..5296
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662986.1"
                     /locus_tag="N6J21_RS02125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_261717453.1"
                     /transl_table=11
                     /translation="MTQNVTSAPLIGRTQELDRLLGVLERARAGEARAVLIAGDAGVGK
                     TRLLDEVAARAARDGMTVLTGHCVDLGDVGLPYLPFTEVLGVLAGDPRFAPVLAAHPVV
                     ERMLGGAADTARDSRLRLFEGMAALLTDLADAAPLLLVLEDLHWADQSSRDLLRFLLSR
                     GVLHRPSGGVAVLASYRADDLHRRHPLRPLLAELVRLPSVERLELRPLADAEVAQLVRA
                     LEERPLPDTTVRRIVERAEGNAFYAEELLAATDAEAGGVPSGLADVLLIRFEQLSDTAQ
                     QVLRTAAVAGRRVEHDLLRETVGIPEDELESALREAVGRQLLVPGDGDTYAFRHALARE
                     AVYADLLPGERSRLHGAFARLLAARPRRAETAAERAHHYRESHDPAEALAASLEAADHA
                     ARVGAPAEELRHLETALDLWPSVDPSARPSGEGVDRVALTLRASSAAAHAGAAHRAVAL
                     TRSALAGLDQEADSELAARVRYTLAGNLLTVDNLSAAYAHSSEALALIPAEPPTATWVW
                     AAATHVLVARQVGEKETALELAREALAVAERLGVTDAAADLLISVAVLEGTGRRSLEGR
                     ARLRQARELARASGNAPVEMRALFSLAVGAFEAGELEESLPWLTEGLDRARRAGLLSSA
                     YPLEMRYLRLLVLYTLGRWDECLRSSAADADLLPALGRFTSGPAWYVSLARGDLSVADT
                     AGALLKGPFDWMGTLVAGIVRTDAAALAGDAEAAVERMRATVTALTDETGALPDVTVRL
                     AALALSAVADRAAGLRSAGDEDGALRWTETATQLVEAARESAGRGKERAPQGPEGMAWL
                     ARAEAEWARATSGPDVDAWAAAVAAFDYGDTYELARCRFRLAEALLTADRREEAATEAR
                     AVRETAERLGAAPLLERVEQLIRRGRLADAPADGTSPLTAREQDVLRLLAQGRTNRQIG
                     EALFISGKTASVHVSNILAKLGAASRGEAVAIAYREGLIAPEHTSSG"
     gene            5517..6713
                     /locus_tag="N6J21_RS02130"
     CDS             5517..6713
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662985.1"
                     /locus_tag="N6J21_RS02130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_261717454.1"
                     /transl_table=11
                     /translation="MNSVSAGKVTAFGTAVLLSLLAAPAHAAPQAPDPDLASLRGVLRT
                     AMKQGAPGAVARIDDEGTVVTTSAGIADRGTERSLAATDRFRIGSVTKIFSAVVLLQLV
                     DEKKLKLDTPVNRYLPGLLPDDRITVRHVLGHRSGLYDYTNDMFARTVPGFEAVRSKVF
                     TYRQLVDRSLRKPRTTAPGGPYSYSNTNFVVAGMLIEKLTGNPVGTEYQQRIVVPLGLK
                     DTFYVHPGKKIPGRYARGYLTPDTSGAALVDATEQTASWAQSAGALISSTRDLNVFLTA
                     LMEGRLMSGTQLTQMRKWVPAGTGQAYGLGLRRRDLSCGVSVYGHTGAVQGYYTYAFAS
                     KDGKRSLAAFVNTSNNGAVHTTMLRSLESAFCGKKTKAVRGKSVGERAEAVDPGAAAH"
     gene            6784..8061
                     /locus_tag="N6J21_RS02135"
     CDS             6784..8061
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1296: tellurium
                     resistance protein, TerD"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662984.1"
                     /locus_tag="N6J21_RS02135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CAP domain-containing protein"
                     /protein_id="WP_261717455.1"
                     /transl_table=11
                     /translation="MSELVPGGNVPLPGGAVAVRVPGPFDVSALVTDDSGKVGGDTDFV
                     FYNQPSAPGVRLDGDTLTVDPARLRAGATRVTVVVSPAEPGTALGALPAPALRVTGAGG
                     RTLARFAPPRPRQETVLLLAELYRRGGGWKLRALGQGYADGLAGLARDFGVDVVDEPPA
                     AAAAPDHDGIAGLVNSARAGAGSPPVTLDARLTAAAREHAAAMAAAGRLGVEGRDGVSV
                     YQRVTAAGYAYLTIGEHLVSGPRSPAEFVDYCLRTGQTRVTLCDPEFTHAGLAHVPARS
                     GDVYWTALWARPFSPADLARTAARVVDLTNRERAGAGLRPLRTDSALTAAAQAHSADMV
                     ARSFYSHTSPEGSQPWDRAAAAGARRRSIGENIACGQRSPAEVVRGWMNSPGHRANILK
                     PGFTHIGIGFAGGGPSGMYWTQLFGA"
     gene            8117..8788
                     /locus_tag="N6J21_RS02140"
     CDS             8117..8788
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662983.1"
                     /locus_tag="N6J21_RS02140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AIM24 family protein"
                     /protein_id="WP_093720717.1"
                     /transl_table=11
                     /translation="MKGDLFSSEHMVQPATAPGMTVENAKCIRYAVSGEMLARQGAMVA
                     YRGSLQFERKGQGVGGMLKRAVTGEGLPLMAVRGQGEAWFAHEAQNCFIVELDPGDEFT
                     VNGRNVLCFDATLSYRISTVKGAGITGGGLFNSVFTGHGRLGLVCDGNPLVIPVSAQYP
                     VYVDTDAVVGWSAGLGTSLHRSQSIGSMLRGGSGEAVQLMLSGEGFVVVRPSEVTPPKT
                     Q"
     gene            8970..10004
                     /locus_tag="N6J21_RS02145"
     CDS             8970..10004
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662982.1"
                     /locus_tag="N6J21_RS02145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_093720718.1"
                     /transl_table=11
                     /translation="MYGKAFAPEYQGALTTLSVNSSLTDVLAAGTEELRAAERTGRHGE
                     AARSGLAVAEAHRRLGQIGEADRAWKASYRSARTAGDTAAMAWALWSGGTLARQRGAFA
                     LARRLLQLAADLGERGGDVVVRGYSLAGLAETGRIQGDYAAVTRLHEQLLAEARRRGEA
                     RHTVWALEGIAQIHRNTGSYDTAFALFEEAAEIAARAEDRRGHAWALRGLADIVSVRDG
                     DIERALELLTEAEATCRQMKLSSALAYNHKMRGNVLYRAGRYTEARDLYTQALDEFRAM
                     GEPRGEALSRLGLAKSRARLGRDHAETAAELAELAGTLERIGLRHAREMVARAQEELGT
                     EAAR"
     gene            10001..11026
                     /locus_tag="N6J21_RS02150"
     CDS             10001..11026
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662981.1"
                     /locus_tag="N6J21_RS02150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_093720719.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 8.7e-62, bitscore:
                     207.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAPSTAPPTAAQVLHRCRDLVRPELERAVARLHPWVGEMAAYS
                     FGWCEVGGAPATAPGGKGVRQALAVLGAEAVGGPARAGTTAAVAVELVHAFSLLHDDIM
                     DGDPTRRGRPTAWRAYGTGPAVLAGDALFALAVETIAEAPAGAPGLRLLSTALGDLVRG
                     QADDLQFADRPWLGPDRVRPEEYRALAEHKTGALLGCAAALGAALGGAPPTTVAALDRA
                     GRELGIAFQIVDDVLGVWGDPAVTGKPVHNDLRARKKTYPVLVALDTPVAGRLAGLLDS
                     GERPEAAAALIEEAGGRSAALREARRRIAAARSALAAVPLDAGTERELGALLEFLVGRQ
                     L"
     misc_feature    10448..10450
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11203..12768
                     /locus_tag="N6J21_RS02155"
     CDS             11203..12768
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003977.1"
                     /locus_tag="N6J21_RS02155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_093720720.1"
                     /sec_met_domain="Pkinase (E-value: 8.7e-20, bitscore: 69.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMVKAHVSTPVWVAGRYRLVDIVHRETNRVCWYAEDSQAERPCL
                     VTGVGLPEDPGGEEAPQVVNRVLRTSERLSLMMPDRVAEVVDVVVESDTLWVVTRWIDG
                     QPLGELLTQRGALNHVRAARIGLELLDVLEAAHGQGVTHGELSPAQVFVRDQGPVVVSG
                     FGLAGATLAPRLAAPAYASPEQARDEGIGPATDLWALGALLYTMVEGRPPFRDRGRPQA
                     TLKAVDRLPLRTPVRAGSLGPTLQGLLRKDPVERLPRSVVREALLDVLDEGTSGAETPD
                     PGLPGRPLGPARWSRRTMVAGTALAVVTVAVAVLAVTGGLPGGSDSTAADSSPRPAPTR
                     TPTSPPAAPPSAPATPTPTATATPSPEGKSPFSRYESPEGFSVTLPEGWKPLSTDRVQD
                     LAYRIVLGAKGDDRTLTVTYSERVGPDPVEVWRDVEPGLKQDGGYRRIGDIRATTYRGR
                     EAAEMEWLMNADGTQVRTLGRGFLLGGSRGYSLRWTAPADAWEDPDNREALATALRTFR
                     EPSE"
     gene            complement(12760..14160)
                     /locus_tag="N6J21_RS02160"
     CDS             complement(12760..14160)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662979.1"
                     /locus_tag="N6J21_RS02160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine hydrolase"
                     /protein_id="WP_093720721.1"
                     /transl_table=11
                     /translation="MTTRALLTSTPAAQGVDSSRVHAFLDALESDPDIEPHSLMILRHD
                     HLVAAGWWAPCAPDRPQLLYSLSKSFTSTAAGFAVAEGLMSLDDPVISYFPEYDAEVTD
                     PRTRAMLVRHVASMASGHEDETLDRARAIDPDDLVHGFLLLPPDRDPGTVFAYNQPATF
                     TLAAIVQRVTGRTLTDYLRPRLFDPIGIGEVAWLRDRAGRELGFSGLHATTDAIARLGQ
                     LYLRGGTWDGRQVLPRSWVAEASRVHTPNADGPMAGADWRQGYGLQFWKSRHGYRGDGA
                     YGQYCLVLPEQDAVIALTSATVEMQRVLDLVWTHLLPACGPDPLTGRERADAALAERLA
                     ALALPPAPGKHAPEPWTAVSFGSDWVSAEVDTAPDGYRLTLVEDGHRIDLRLVPGEWTV
                     TEEPVPTAVSGGWSDADTLEAEVLFLETPHRLAVTCSLPDRTCTARWRTVPLHPRPLRR
                     TGAPRRSL"
     gene            14224..15195
                     /locus_tag="N6J21_RS02165"
     CDS             14224..15195
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987907.1"
                     /locus_tag="N6J21_RS02165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_261717456.1"
                     /transl_table=11
                     /translation="MVQIGYTMMTEQAGPRDLVDHVVRAEEAGFDFSVTSDHYFPWLRA
                     QGHSPYAWSVLGAAAQATRRIPLMTYVTCPTFRYHPAVVAQKAATVQLLSEGRFRLGLG
                     SGENLNEHVVGGGWPSVEVRHEMLEEAIGIIRALFEGGHVSRHGTHYDVDSARLWDLPD
                     PPPPIGVAVSGERSCALAGRLADLVIATEPKPGLLDSFDRLGGSGKPRVGQLPVCHDAD
                     RDTAVRRAHAQFRWFGGGWKVNSELPHPDSFEAATQYVTPDDVAAAIPCGDDPDDFVEA
                     VRPYVEAGFDEVALVQIGGESQPAYLDWSEKTLLPALRNAFG"
     cand_cluster    14349..24726
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    14349..24726
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[19348:19726](+)"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      19349..19726
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
     gene            15284..16309
                     /locus_tag="N6J21_RS02170"
     CDS             15284..16309
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662978.1"
                     /locus_tag="N6J21_RS02170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_093720723.1"
                     /transl_table=11
                     /translation="MTLALVPSETSPVPLSDLVARDAREFGAYARTGGWAFALMVARSV
                     RPGGQGAEETPKVSAKEFAELAGCSPERVMRYYRAWDRAADDGLVPQFEALRPGAEVEL
                     PDADVWLSYYVSRNSATSERGTAIAEAAEAEGIRPTKALEVAENPTALRAAILADPSTA
                     RAARSALLDRVKEDPELQVELARDVVRTDDLKKAVASESRAADRIGYVRQIAESGQVKT
                     PAGQTIEAPVELRQEAERHLSLIDELDEDEDTGEWATEAYDTLRSLVAETVEADPELRV
                     QERRTKFYSSLQRATKVFEELTFDDVQEFAEDDMVRQLEDLQQAITSCIAALKGGQSRE
                     V"
     gene            complement(16291..16785)
                     /locus_tag="N6J21_RS02175"
     CDS             complement(16291..16785)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069195.1"
                     /locus_tag="N6J21_RS02175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6328 family protein"
                     /protein_id="WP_261717457.1"
                     /transl_table=11
                     /translation="MATQEPAKRTGRNETEDERADRMWGELMQEVRVAQMGVQILFGFL
                     LTVVFTPKYDDLGDTEKTIYLVTVVVGAAATGALIGPVSLHRIVSGRRIKPRAVEWASR
                     LTFIGLVLLLITMASSLLLILRVATHDGYVPWIVTGIVLWYLVCWFGLGWWIRRRYTSR
                     D"
     misc_feature    16809..16823
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.72"
                     /tool="antismash"
     gene            complement(16822..17805)
                     /locus_tag="N6J21_RS02180"
     CDS             complement(16822..17805)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433219.1"
                     /locus_tag="N6J21_RS02180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldo/keto reductase"
                     /protein_id="WP_250754935.1"
                     /transl_table=11
                     /translation="MEERTFSRSQQHASVIGLGTWQLGADWGDVDDKEALKVLETAAET
                     GVTFFDTADVYGDGRSEQTIAAFLSGRPDLHVMVATKMGRRVEQIPENYVLDNFRAWND
                     RSRRNLGVDRIDLVQLHCPPTPVYSSDEVFDALDTLVAEERIAAYGVSVETCAEALTAI
                     ARPGVASVQIILNPFRMKPLYEVLPAAREAGVGIIARVPLASGLLSGKYTKDTVFPEND
                     HRTYNRHGESFDQGETFSGVDYATGVEAAAEFSALAPEGFTPAQLALRWIVQQPGVTTV
                     IPGARSPEQARANASAAALPELSAETLDAIRELYERRIKEQVEARW"
     gene            complement(17810..19000)
                     /locus_tag="N6J21_RS02185"
     CDS             complement(17810..19000)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662975.1"
                     /locus_tag="N6J21_RS02185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_250754933.1"
                     /transl_table=11
                     /translation="MKVVCVGGGPAGLYLSILLKLADPSHDITVYERNPEGSTYGWGVT
                     YWRGLLDKLQMHDPVSARAIADHSVTWNEGVARVRDQVTRHRGDQGFGIGRHRLLELLA
                     ARARSLGVHLEYAHEIDADGPLPEADLVVAADGVHSALRTRHAEHFGARLTPGRNHYIW
                     LGTSKVFDTFTFSFVETEHGWIWAYGYGFSPERSTCVIECSPETFTGLGLDRADEADGL
                     VLLEKLFADTLDGHALIGRAPADGSSPWLHFRTLTNRTWHRDNLVLLGDAAHTTHYSIG
                     AGTTLALEDALALAGALRDHTDLPQALAHYERARKQELLPLQSAARHSAQWYENLTRYI
                     DLPPEQMFALLGQRHSPLLPYVPPQLYYRLDRAAGRLEALRRLKRWLGPKLARVTD"
     misc_feature    19015..19029
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     misc_feature    19228..19242
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.66"
                     /tool="antismash"
     gene            19349..19726
                     /locus_tag="N6J21_RS02190"
     CDS             19349..19726
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138613.1"
                     /locus_tag="N6J21_RS02190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosinase cofactor"
                     /protein_id="WP_093720727.1"
                     /sec_met_domain="melC (E-value: 2.3e-48, bitscore: 162.7,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPELTRRRALTAAAALAAASGAATLAAPAARAAGHHPDPSPAAFD
                     EVYKGRRIQGRVRSGGGHHHDHGGGYGVYIDDVELHVMRNADGSWISVVSHYDPVATPR
                     AAARAAVDELQGAELLPFPAN"
     gene            19761..20585
                     /locus_tag="N6J21_RS02195"
     CDS             19761..20585
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662973.1"
                     /locus_tag="N6J21_RS02195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosinase family protein"
                     /protein_id="WP_261717458.1"
                     /transl_table=11
                     /translation="MTVRKNQANLTADEKRRLVAALLELKRSGRYDDFVRIHNDFIVGD
                     TDNGERTGHRSPSFLPWHRRFLLEFEAALQEVDASVALPYWDWTTDRTPRASLWAPDFL
                     GGTGRSLDGRVMDGPFAASTGNWPINVRVDGRTYLRRSLGSGGRPLPTRAEVESVLAIE
                     TYDMPPWNSGSDGFRNHLEGWRGVNLHNRVHVWVGGQMATGVSPNDPVFWLHHAYVDKL
                     WSQWQRRHPNSPYLPATGTPDVVHLNGTMKPWNNVRPAELLDHTRHYTFDVA"
     gene            complement(20592..21275)
                     /locus_tag="N6J21_RS02200"
     CDS             complement(20592..21275)
                     /EC_number="3.1.26.4"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126205.1"
                     /locus_tag="N6J21_RS02200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribonuclease H"
                     /protein_id="WP_250754932.1"
                     /transl_table=11
                     /translation="MRERVVAACDGASKGNPGPAGWAWVVADESETPARWEAGPLGRAT
                     NNVAELTALERLLAATDPEVPLEVRMDSQYAMKAVTTWLPGWKRNGWKTSAGKPVANQE
                     LVVRIDELLAGRSVEFRYVPAHQVDGDKLNDFADRAASQAATVQEPAGSELGSPEPPPS
                     PDTPVKAPRRRPAAAKKSGGGSSARTIKAKFPGRCVCGRSYAAGEQIAKNAQGWGHPEC
                     RTAEA"
     gene            complement(21311..22111)
                     /locus_tag="N6J21_RS02205"
     CDS             complement(21311..22111)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670773.1"
                     /locus_tag="N6J21_RS02205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_093720793.1"
                     /transl_table=11
                     /translation="MAVQPEGTPCWADAMFSDFEGAKSFYGDVLGWTFGESSSEFGNYT
                     QAYADGKAAAAVVPPMPGQEGMSQWCLYLASPDAAETARRIRDNGGEVLMEPMQVSDFG
                     TMCLARDPSGVVFGVWQAGTHEGFEAPPEQPGAFAWAEVFTREPDKSDAFFPAVFPRYT
                     AQQMEDDGMDFRVFNIADTPVLGRMKMTEEFPPEVPAYINVYFSVPDVDATVAKATERG
                     GVLRFGPVDTPFGRIAALSDPQGANFSVIDVTTTEGEMPKLTDV"
     gene            22261..23268
                     /locus_tag="N6J21_RS02210"
     CDS             22261..23268
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0004024 - alcohol dehydrogenase (NAD+)
                     activity, zinc-dependent [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433225.1"
                     /locus_tag="N6J21_RS02210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_261720558.1"
                     /sec_met_domain="ADH_N (E-value: 2.3e-31, bitscore: 106.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAWSVVAPGPVEEGALRLVEKPVPAPGDGELLVRVLACGVCRTD
                     LHVTEGDLPVRRAGVTPGHEVVGEVAGLGAGVSGFTVGDRVGVAWLRWTDGTCAYCLRG
                     AENLCPGSRYTGWDTDGGYAEYTTVPADFAHPLPAGLTDLALAPLLCAGIIGYRALRRA
                     SLPAGGRLGLYGFGGSAHLCAQVALAEGARVHVLTRGAAARRLALELGAASAGEAHTMP
                     PEPLDSAILFAPVGDLVPVALRALDRGGVLAVAGIHLTDTPPLHYETDLFYEKELRSVT
                     SNTRADARKFLTLAARYKVHATTHAYPLSRADVALRDLKAGRFDGAAVLVNDLS"
     gene            23371..24267
                     /locus_tag="N6J21_RS02215"
     CDS             23371..24267
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662964.1"
                     /locus_tag="N6J21_RS02215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_261717459.1"
                     /transl_table=11
                     /translation="MRRAWMAGLALGVALLGGCGDPASEPERAPAPAKPRASATTQQRA
                     PASPKAPAKPPKVLYLGDSLAMEAQNVLGAELRGRLRAAYTSAPYSGTTVCDYLEGTGE
                     RSLVPDADKAAALVRAHRPDFVVLQFWGNSWGYTPCMDGITHDAGPRAYFDRYTADLDR
                     LTSQIAAAGGEHRPRIVWVLQGPDPITPDRVRKVNALYEERAGAAGDLVADAGRTVSAD
                     GARYTWVRQLPCTAYERAHPDYCTDPGRDRTALHREDDYLHFCLAPTTSTPKPCPVRSP
                     GILRMAQEVTRVIRGAR"
ORIGIN
        1 acctgtccaa gggcgccaag tcggtgacgc tgctggtgcg cggggccgat ctgtcggcgt
       61 ccatgtcgca ctacctgatc cagcagatca acgaggcacc caacatctcc gtccgcccgc
      121 gcaccgtcgt ggacgccgcc cacggcgagg gccacctcca gcagctcacc ctgcgcgacg
      181 tggacaccgg ggagagcgaa ctcgtcgacg cccagtggct gttcgtgttc atcggcgcgg
      241 ccccgctgac cgactggctg gacggcaccg tgctgcgcga cgcgaacggc ttcatcctcg
      301 ccgggcccga cctcaccccc gacggacggc cccccgcggg ctgggagctg gaccggccgc
      361 cgtaccacct ggagaccaat gtgcccgggg tgttcgtggc cggtgacgcg cgcgccgagt
      421 ccgccaagcg cgtcgcctcc gccgtgggcg agggggcgat ggccgtgatg ctcgtccacc
      481 gctatctgga gcagtcgtga accgacgtca ggagcagtcg tgagcggaat gcccatgccg
      541 tgcagtccgg cggagatcag ctcgctgttc ctgttcgaga agctcgcccc ggagcagctc
      601 ggccgactgt gcgcggaagg gcgggtggag cggttcgagc cgggcccggt ctacaccgag
      661 ggggatccgg cgacctgctt ctacgtcatg atcgagggca ccgtcgtgct ctcccgccgg
      721 gtcggcgggg acgacgtcga ggtgatccgc agctcccagc gcggggtgta ctcgggggcg
      781 atgcaggcct acctcggcga ccgggcgcgc caggtctaca acaactccat gcgggtgacc
      841 gaaccgaccc ggttcttcgt gctgcccgcg gacaccttcg cggccgtcat gcaggagtgg
      901 ttcccgatgg ccgtgcatct gctggaggga ctgttcttcg gcgcgaagaa cacccagcag
      961 gtgatcgggc agcgggaacg gctgctggcg ctcggctcac tgtccgccgg gctcacccac
     1021 gagctcaaca accccgccgc cgcggccgtc cgggcgaccg ccaccctgcg ggagcgggtg
     1081 gcgaagatgc ggcacaagct ggcgatgatc gcctccggcc cgtatccgcg ggagcagctg
     1141 gccgggctga tcgagatcca ggaacgcacc gccgaactgg tcggcaaggc gcccgcgctc
     1201 agcccgctgg aggcgtccga ccgggaggac acgctcaccg actggctgga cgaccacggc
     1261 atccccgacg gctggcggct cgccccgacc ttcgtacagg ccgggctcga catcgactgg
     1321 ctggagcagg tcgcggcggc cgtgcccgag gaggtcctgc cgggcgccgt cggctggctc
     1381 aactacacgg tcgagaccga gctgttgatg agcgagatcg aggactccac cacccgggtc
     1441 tcgcacctgg tcgacgcggc caagcagtac tcccagctcg accgcgcccc cttccgcacc
     1501 gtcgacgtcc acgaactcct cgacagcacc ctgatgatgc tcgccgggaa gatcggcccg
     1561 cggatcaagg tcgtcaagga gtacgaccgt acgctcccgg agatccccgc ctacccggcg
     1621 gagctcaacc aggtgtggac gaacctcgtc gacaacgcgg tcgccgccat caacagcgcg
     1681 ggcggggaag ggacgttgac cgtccggacg gcgaccgacc acgaccggct gctggtggag
     1741 ttccgggaca cgggcaccgg tatcccgccg gagatccgcg gccggatctt cgatccgttc
     1801 ttcaccacca agccggtggg cgagggcacc gggctcggtc tggacatctc ctggcggatc
     1861 gtggtcaaca agcaccacgg cacactccag gtcgagtccg agccgggcga cacccgtttc
     1921 caggtgctgc tcccgctcac cgccgcggac cacgagaacc ccgaggagag cccatgaccg
     1981 acggcatcga tccgagcgtc ccgccgagcg gcaccggctg cgcggagtgc gacgaggtcg
     2041 ggggctggtg gttccatctg cggcggtgcg cccagtgcgg gcacatcggc tgctgcgact
     2101 cctcgcccgg caagcacgcc accgcgcact tccgggccac cgggcatccg atcgtgcaga
     2161 gcttcgagcc cggcgagggc tggttctggg actacggcgc ctccgacctg tacgaatcgg
     2221 gcccggaact ggcgcccccg gccagccatc cggccgacca gcccgcaccg gggcccgcgg
     2281 gccgggtgcc cggcaactgg gcgcaggtgc tgcggggcgc ctgactccgt gaccgctccg
     2341 gcgcgtctgg caggattggc cagtgacaca gaacgtgacc tccgccccgc tcatcggccg
     2401 tacgcaggaa ctcgaccggc tcctgggtgt gttggagcgg gcgagggccg gtgaggcacg
     2461 ggccgtactg atcgcggggg acgccggggt cggcaagacc cgtctgctgg acgaggtcgc
     2521 cgcgcgggcc gcgcgcgacg ggatgaccgt gctcaccggg cactgtgtcg acctgggcga
     2581 tgtgggtctg ccgtatctgc cgttcaccga ggtgctcggg gtactggccg gggacccgcg
     2641 gttcgcgccg gtgctggcgg cgcatccggt ggtcgagcgg atgctgggcg gcgccgcgga
     2701 caccgcccgc gactcccggc tgcggctgtt cgagggcatg gccgcgctgc tgacggacct
     2761 cgcggacgcg gccccgctgc tgctggtcct ggaggacctg cactgggccg accagtcctc
     2821 ccgggacctg ctgcggttcc tgctcagccg gggcgtgctg caccggccgt ccggcggggt
     2881 cgcggtcctg gcctcctacc gcgccgacga cctgcaccgc cgccaccccc tgcgccctct
     2941 gctggcggaa ctggtccggc tgccctccgt ggagcgcctg gagctgcggc cgctggccga
     3001 cgccgaggtc gcccagctcg tacgggccct ggaggaaagg ccgctgccgg acaccacggt
     3061 ccggcggatc gtcgagcgcg ccgagggcaa cgccttctac gccgaggaac tcctcgccgc
     3121 caccgacgcc gaggccggcg gggtgcccag cgggctcgcc gacgtcctgc tgatccgctt
     3181 cgagcaactg tccgacaccg cccagcaggt gctgcgcacc gccgcggtcg ccggacgccg
     3241 ggtcgagcac gacctgctgc gggagacggt cggcatcccc gaggacgagc tggagtcggc
     3301 gctgcgcgag gcggtgggcc gccaactgct ggtccccggc gacggagaca cctacgcctt
     3361 ccggcacgcc ctggcccgcg aggcggtcta cgccgatctg ctgcccggcg aacggtcccg
     3421 gctgcacggc gcgttcgccc ggctgctcgc cgcccggccc cggcgcgccg agaccgccgc
     3481 cgagcgcgcc caccactatc gcgagagcca cgacccggcc gaggcgctcg ccgcttccct
     3541 ggaggccgcc gaccacgccg cccgggtcgg cgcccccgcc gaggagctgc ggcacctgga
     3601 gaccgccctg gacctgtggc cgtcggtgga tccgtccgcg cgcccctcgg gcgagggcgt
     3661 ggaccgggtg gcgctcaccc tgcgcgcctc ctcggcggcg gcgcacgccg gggccgcgca
     3721 ccgcgcggtc gccctgaccc ggtccgcgct cgcgggcctc gaccaggagg cggactcgga
     3781 gctggccgcc cgggtccgct acaccctcgc gggcaacctc ctcaccgttg acaacctgag
     3841 cgccgcctac gcgcacagca gcgaggcgct cgccctgatc cccgccgagc cgcccacggc
     3901 gacctgggtg tgggcggcgg ccacccatgt gctggtggca cggcaggtcg gggagaagga
     3961 gacggcgttg gagctggccc gagaggcgct ggcggtcgcc gagcggctgg gggtgaccga
     4021 cgccgcggcc gatctgctga tctcggtggc ggtgctggag ggcaccggac ggcgcagcct
     4081 tgagggccgg gcccggctgc ggcaggcgcg ggagctggcc cgcgcctcgg gcaacgcgcc
     4141 ggtggagatg cgcgccctgt tcagcctcgc cgtgggcgcc ttcgaggcgg gcgagctgga
     4201 ggagtccctg ccgtggctga ccgagggcct ggaccgggcc cggcgtgccg ggctgctgtc
     4261 ctcggcgtac ccgctggaga tgcgctatct gcggctgctg gtgctgtaca cgctgggccg
     4321 ctgggacgag tgcctgcggt cctcggcggc cgacgcggac ctgctgcccg ccctgggccg
     4381 gttcacctcg gggcccgcct ggtacgtgtc gctggcgcgc ggagacctgt ccgtcgccga
     4441 cacggcgggg gcgctgctca aggggccgtt cgactggatg ggcacgctgg tcgcgggcat
     4501 cgtgcggacc gacgcggccg cgctcgcggg cgatgcggag gcggcggtgg agcggatgcg
     4561 ggccacggtg accgcgctga ccgacgagac gggcgcgctg cccgatgtga cggtccgtct
     4621 ggccgcgctg gcgctgtccg ccgtggccga ccgtgcggcc ggcctgcgct cggccgggga
     4681 cgaggacggg gcactgcgct ggacggagac cgcgacacaa ctcgtcgagg cggcgcggga
     4741 gtcggcggga cgcggcaagg aacgggcgcc gcagggcccg gaggggatgg cgtggctggc
     4801 ccgcgccgag gccgagtggg cgcgggcgac gtcgggtccg gacgtggacg cctgggccgc
     4861 ggcggtggcg gccttcgact acggcgacac ctacgagctg gcgcgctgcc ggttccgtct
     4921 tgccgaggca ctgctcaccg ccgaccggcg cgaggaggcc gcgacggagg cgcgggcggt
     4981 ccgggagacc gccgaacggc tcggcgcggc gccgctgctg gaacgcgtgg agcagctgat
     5041 ccggcgcgga cggctggccg acgcgcccgc cgacggcacg tcaccgctga ccgcgcgcga
     5101 gcaggacgta ctgcggctgc tcgcccaggg ccgcaccaac cggcagatcg gcgaggccct
     5161 gttcatcagc ggcaagaccg cgagcgtcca tgtctccaac atcctcgcca agctgggcgc
     5221 cgcgagccgc ggcgaggcgg tggcgatcgc ctaccgcgaa gggctgatcg cgccggagca
     5281 cacctcctcc ggctgatccg gccgggacct gcccccgccg ggacccgagc acccctcccg
     5341 gccgaccctg ccggggccgg agcacacctc ccctgctgac cctgccgcca ccggaccgtc
     5401 cgtcccccag tcgggcgatc cctgcccgcc cctgccctga atggccatcc ttctttctcc
     5461 tgccggcact actgtgcgtc gccgtgacgg tgtgtcagcg aggagagagg aaccggatga
     5521 actcggtatc ggcgggcaag gtcacggcgt tcgggacagc ggtcctgctc tccctcctgg
     5581 cggcaccggc gcacgcggca ccccaggcac ccgacccgga cctggcgtcc ctgcggggcg
     5641 tgctgcgcac cgcgatgaag cagggcgcgc cgggcgcggt ggcgcggatc gacgacgagg
     5701 gcacggtcgt caccacgtcc gccggtatcg ccgaccgcgg caccgaacgg tctctggccg
     5761 ccaccgaccg cttccgcatc ggcagcgtga ccaagatctt ctccgccgtc gtgctgctgc
     5821 aactggtcga cgagaagaag ctcaagctcg acaccccggt caaccgctat ctgcccgggc
     5881 tgctgccgga cgaccggatc accgtgcgcc atgttctcgg ccaccgcagc ggcctgtacg
     5941 actacaccaa cgacatgttc gccaggacgg ttcccggctt cgaggcggtc cgttccaagg
     6001 tcttcaccta ccgccagctc gtggaccgct ccctgcgcaa gccgcgcacc accgcgccgg
     6061 gcggcccgta ctcgtactcc aacaccaatt tcgtcgtcgc cgggatgctc atcgagaagc
     6121 tgaccgggaa cccggtgggt accgagtacc agcagcggat cgtcgtgccg ctggggctga
     6181 aggacacctt ctacgtgcac cccgggaaga agatcccggg acggtacgcg cgcggctacc
     6241 tcaccccgga cacgtccggc gcggcgctgg tcgacgccac cgagcagacg gcgtcctggg
     6301 cgcagagcgc gggcgcgctg atctccagca cccgggacct gaacgtcttc ctgaccgccc
     6361 tgatggaggg caggctgatg tcgggcacgc agctcacaca gatgcgcaag tgggtgccgg
     6421 cgggcaccgg ccaggcgtac gggctggggc tgcggcggcg cgatctgtcc tgcggggtct
     6481 cggtgtacgg gcacaccggg gccgtccagg gctactacac ctacgcgttc gcctccaagg
     6541 acggcaagcg gagcctggcg gccttcgtca acacctccaa caacggcgcc gtgcacacca
     6601 ccatgctccg ctcgctggag tcggcgttct gcgggaagaa gaccaaggcg gtgcgcggca
     6661 aatcggtggg tgagcgggcc gaggccgtcg atccgggggc cgccgcgcac tgaccggccg
     6721 ggaacccgag ccgggtcgtc cgcgttgtcc gagcaccacg tacgacgaca cctggacggc
     6781 ctgatgagcg agttggtccc cgggggcaat gtgcctctcc cgggcggtgc cgtggccgtc
     6841 cgggtgcccg gccccttcga tgtgtccgcg ctggtcacgg acgacagcgg gaaggtgggc
     6901 ggggacaccg acttcgtgtt ctacaaccag ccgtccgccc ccggtgtgcg gctggacggc
     6961 gacaccctga ccgtcgaccc ggcccggctg cgcgcgggcg ccacccgggt cacggtcgtg
     7021 gtcagccccg ccgagcccgg caccgccctg ggcgcgctgc ccgcccccgc gctccgcgtc
     7081 accggtgcgg gcggccgtac cctcgcccgg ttcgccccgc cgcgcccccg gcaggagacg
     7141 gtgctgctgc tcgccgaact gtaccggcgc ggcggcggct ggaagctgcg ggcactgggc
     7201 caagggtacg ccgacggact ggcgggactg gcccgggact tcggggtgga cgtcgtagac
     7261 gagccgcccg ccgcggccgc ggcacccgac cacgacggca tcgcgggact ggtcaactcg
     7321 gcccgtgcgg gcgccggttc gccgccggtg acgttggacg cccggctcac cgccgccgcc
     7381 cgggagcacg ccgccgccat ggccgcggcg ggacggctgg gtgtggaggg ccgggacggg
     7441 gtctccgtct accagcgggt gacggcagcc gggtacgcgt acctcaccat cggggagcac
     7501 ctggtgtccg gaccgcgctc ccccgccgag ttcgtcgact actgcctgcg caccggccag
     7561 acgcgcgtaa ccctgtgcga cccggagttc acgcacgccg gactggccca cgtgcccgcc
     7621 cgctccggcg atgtgtactg gacggcgctg tgggcccgcc ctttcagccc ggcggacctg
     7681 gcccggaccg ccgcgcgggt cgtcgacctc accaaccggg agcgcgccgg ggccggtctg
     7741 cgcccgctcc ggaccgactc cgccctcacg gccgccgccc aggcgcacag cgcggacatg
     7801 gtggcgcggt ccttctactc gcacacctcg cccgaggggt cgcagccctg ggaccgggct
     7861 gccgcggcgg gcgcccggcg ccggtcgatc ggcgagaaca tagcctgcgg gcagcgctcc
     7921 cccgccgaag tcgtacgagg ctggatgaac agtcccggcc accgcgccaa catcctcaag
     7981 ccgggcttca cgcacatcgg catcggtttc gcgggcggcg gcccgtccgg tatgtactgg
     8041 acccaactct tcggcgcctg aaggatcgtg ggacgcgatc ttggcggagg gacctcgtcc
     8101 gcgacacgat gcccgcatga agggtgacct gttttccagc gagcacatgg tccagcccgc
     8161 cacggcgccg ggcatgacgg tcgagaacgc caagtgcatc cggtacgcgg tgagcggcga
     8221 gatgctggcc cggcaggggg cgatggtcgc ctaccggggc agtctccagt tcgagcgcaa
     8281 gggccagggc gtgggcggga tgctcaagcg cgcggtcacc ggggaggggc tgccgctgat
     8341 ggcggtgcgc gggcagggtg aggcgtggtt cgcgcacgag gcgcagaact gtttcatcgt
     8401 cgagctcgac cccggtgacg agttcacggt caacggccgc aacgtgctgt gcttcgacgc
     8461 cacactgtcc taccggatat ccaccgtgaa gggggcgggc atcaccggcg gcgggctgtt
     8521 caacagcgtg ttcaccgggc acgggcggct cgggctggtc tgcgacggga atccgctggt
     8581 gataccggtg tccgcgcagt acccggtcta cgtcgacacc gacgcggtgg tcggctggag
     8641 cgcgggcctg gggacctcgc tgcaccgctc gcagtccatc ggctcgatgc tgcgcggcgg
     8701 ttccggcgag gccgtgcagc tgatgctcag cggcgagggc ttcgtggtgg tccggccgag
     8761 cgaggtgaca ccgcccaaga cccagtagcc cgagggcccg tgaggtgatc tgcgcctcac
     8821 gggcaacccc gtacgcccgg tccgcgtctt gatcgacaac agatgacacc cccctggccc
     8881 cctggggccg ggggtggttt ccgttgctct atacacacca tgtatacatg caatgtatag
     8941 atggtgtgca tacggaccga aaggcatcca tgtacggcaa ggcattcgcc ccggagtacc
     9001 agggggccct gaccaccctc tccgtgaact cctcgctcac cgacgtactc gcggccggca
     9061 ccgaggaact gcgggccgcc gagcggaccg ggcggcacgg cgaggcggcg cgatccgggc
     9121 tggcggtcgc cgaggcgcac cgcaggctgg ggcagatcgg ggaggcggac cgggcgtgga
     9181 aggcgagcta ccgctccgcc cgcacggccg gggacaccgc ggcgatggcg tgggcgctgt
     9241 ggagcggcgg caccctggcc cggcagcgcg gcgcgttcgc gctggcccgg cggctgctcc
     9301 agctcgccgc cgacctcggt gagcgcggcg gcgacgtcgt cgtacgcggc tactcgctgg
     9361 ccgggctcgc cgagaccggc cggatccagg gcgactacgc ggccgtgacc cggctgcacg
     9421 agcagttgct ggccgaggcc cggcggcgcg gcgaggcccg ccacacggtg tgggcgctgg
     9481 agggcatcgc gcagatccac cgcaacaccg gttcctacga caccgcgttc gcgctgttcg
     9541 aggaggccgc cgagatcgcc gcgcgcgccg aggaccggcg cgggcacgcc tgggcgctgc
     9601 gcggactcgc cgacatcgtc tcggtgcgtg acggcgacat cgagcgcgct ctggagctgc
     9661 tgacggaggc ggaggcgacc tgccggcaga tgaagctgtc cagcgcgctg gcctacaacc
     9721 acaagatgcg cggcaacgtc ctgtaccgcg cgggccgtta caccgaggcc cgcgacctgt
     9781 acacgcaggc gctcgacgag ttccgtgcca tgggtgagcc gcgcggcgag gcgctgtccc
     9841 ggctcgggct cgccaagtcc cgggcccggc tgggccgcga ccacgccgag acggccgccg
     9901 aactggcgga gctggcaggc acgttggagc gcatcggcct gcggcacgcc cgggagatgg
     9961 tggcccgcgc ccaggaggag ctgggtacgg aggcggcacg gtgaccgcgg ccccgtcgac
    10021 ggcgcccccg accgccgccc aagtactgca ccgctgccgg gacttggtcc gcccggagct
    10081 ggaacgggcc gtggcccggc tgcatccctg ggtcggtgag atggccgcct actccttcgg
    10141 ctggtgcgag gtgggcggcg ccccggccac cgccccggga ggcaagggag tgcggcaggc
    10201 gctggccgtg ctgggcgccg aggcggtcgg cggcccggcc cgggccggta ccacggcggc
    10261 cgtcgccgtg gaactcgtgc acgccttctc cctgctgcac gacgacatca tggacggcga
    10321 cccgacccgc cgcggccgcc cgaccgcgtg gcgggcctac ggcaccggcc cggccgtcct
    10381 cgcgggcgac gccctgttcg ccctcgccgt ggagacgatc gccgaggccc cggccggcgc
    10441 acccggttta cggctgctgt ccacggcgct cggggacctg gtgcgcggac aggcggacga
    10501 tctgcagttc gcggaccggc cctggctggg cccggaccgg gtgcggccgg aggagtaccg
    10561 ggcgctggcc gagcacaaga cgggcgccct gctgggctgc gccgccgccc tgggcgccgc
    10621 gctcggcggg gccccgccca ccacggtcgc cgcgctcgac cgggccggac gcgaactggg
    10681 catcgccttc cagatcgtcg acgacgtgct cggcgtgtgg ggcgacccgg ccgtcaccgg
    10741 caagcctgtg cacaacgatc tgcgggcccg caagaagacc tacccggtgc tggtcgccct
    10801 ggacacgccg gtcgcggggc ggctggccgg gctgctggac tcgggcgagc ggccggaggc
    10861 agcggcggcg ctgatcgagg aggcgggcgg ccggtcggcg gccctgcgcg aggcgcggcg
    10921 ccggatcgcc gccgcccggt ccgccctggc cgccgtaccc ctggacgcgg gcacggaacg
    10981 ggagttgggg gcgctgctgg agttcctggt gggcagacag ctctgaaccg cgcgttcgat
    11041 ccgccggccg gcgcccaccg gatcaccccc ggtccgggac gcgtgttcga cccaccggtc
    11101 ggcgtacggg agttggcgca tatcggtcga cggatccttg aacggacccg gtcacgcgcg
    11161 ccgtacctct gggaaaggtg agagcccggg gttcagcgag ggatgaccat ggtcaaggcg
    11221 cacgtctcca cgcccgtgtg ggtcgccggg aggtaccggc tcgtcgacat cgtccaccgg
    11281 gagaccaacc gcgtctgctg gtacgccgag gacagccagg cggaacggcc ctgtctggtg
    11341 accggggtcg ggctgccgga ggatcccggc ggcgaggagg cgccgcaggt cgtcaaccgc
    11401 gttctgcgca cgtccgagcg gctgtcgctg atgatgcccg accgggtcgc cgaagttgtc
    11461 gacgtggtcg tggagtcgga caccctgtgg gtggtgaccc ggtggatcga cggtcagccg
    11521 ctgggcgaac tcctcaccca gcggggcgcg ttgaaccacg tgcgggcggc ccggatcggg
    11581 ctggagctgc tcgacgtact ggaggcggcg cacgggcagg gcgtcaccca cggcgaactc
    11641 agcccggcgc aggtgttcgt gcgcgaccag ggccccgtgg tggtctccgg tttcggactg
    11701 gccggggcca ccctggcacc ccggctggcc gcgcccgcgt acgcctcccc cgagcaggcc
    11761 cgcgacgagg ggatcggccc ggccaccgat ctgtgggcgc tcggcgcgct gctctacacg
    11821 atggtggagg gccgcccgcc gttccgggac cggggccgcc cgcaggccac gttgaaggcg
    11881 gtcgaccggt tgccgctgcg caccccggtc cgggccgggt cgctcggccc gacgttgcag
    11941 ggcctgctcc gcaaggaccc cgtggagcgg ctgccccgtt cggtggtccg tgaggcgctg
    12001 ctggacgtcc tggacgaagg cacctcgggg gcggagacgc cggacccggg gctgccgggc
    12061 cggcccctcg gcccggcgcg ctggagccgg cggaccatgg tcgccgggac cgcgctggcc
    12121 gtggtcacgg tcgcggtggc cgtgctcgcg gtcacgggcg ggctgcccgg cggctcggac
    12181 tccaccgccg ccgattcctc gccccgcccg gccccgacgc gcaccccgac gtcccctcct
    12241 gcagctccgc cgtccgcccc ggccaccccc acccccaccg ccaccgccac ccccagcccg
    12301 gaggggaagt ccccgttcag ccgctacgag tcgcccgagg gcttctccgt cacgctcccc
    12361 gaggggtgga agccgctcag caccgaccgg gtccaggacc tggcgtaccg gatcgtgctc
    12421 ggcgccaagg gcgacgaccg cacgctgacc gtcacctaca gcgaacgggt gggtccggac
    12481 cccgtcgagg tgtggcggga cgtggagccc ggcctgaagc aggacggcgg gtaccgccgg
    12541 atcggcgaca tccgggcgac gacctaccgg ggccgggagg ccgccgagat ggagtggctc
    12601 atgaacgccg acggcaccca ggtccgcacc ctgggccgcg gtttcctcct cggcggcagc
    12661 cgcggctact cgctgcgctg gacggccccc gcggatgcct gggaggaccc ggacaaccgc
    12721 gaggccctgg ccacggccct gcgcacgttc cgggagccgt cagagtgacc tgcggggcgc
    12781 gccggtcctg cgcagcgggc gcgggtgcag gggcacggtg cgccagcggg cggtgcaggt
    12841 gcggtccggg agcgagcagg tcacggcgag ccggtgcggg gtctccagga acagcacctc
    12901 cgcctccagg gtgtcggcgt cgctccagcc gccgctgacc gcggtgggca ccggctcctc
    12961 ggtgacggtc cactcgcccg gcaccagacg gagatcgatc cggtgcccgt cctccaccag
    13021 cgtcagccgg tagccgtcgg gcgcggtgtc gacctccgcg gagacccagt cggagccgaa
    13081 ggagacggcc gtccacggct cgggcgcgtg cttgccgggg gccgggggaa gcgcgagggc
    13141 cgccagccgt tcggcgaggg cggcgtcggc ccgctcgcgg ccggtgagcg ggtcggggcc
    13201 gcaggcgggc agcaggtgcg tccagaccag gtccagcacc cgctgcatct ccacggtggc
    13261 ggaggtcagg gcgatcacgg cgtcctgctc gggcaggacc aggcagtact gcccgtaggc
    13321 gccgtccccg cggtagccgt gccgggactt ccagaactgc agcccgtacc cctgccgcca
    13381 gtcggcaccg gccatcggcc cgtcggcgtt cggggtgtgg acacggctcg cctcggccac
    13441 ccaggagcgc ggcagcacct gccgcccgtc ccacgtccca ccccgcagat acagctgccc
    13501 cagccgggcg atcgcgtcgg tcgtggcgtg cagcccgctg aaccccagct cccggcccgc
    13561 ccggtcgcgc agccacgcca cctcgccgat gccgatcggg tcgaacagtc gggggcgcag
    13621 atagtcggtg agcgtccggc cggtcacgcg ctggacgatc gcggcgagcg tgaaggtggc
    13681 gggctggttg tacgcgaaca cggtgcccgg gtcacggtcg ggcggcagca gcaggaagcc
    13741 gtgcaccagg tcgtcggggt cgatcgcgcg ggcccggtcg agggtctcgt cctcgtgtcc
    13801 gctggccatg gaggccacgt gccggaccag catggcgcgg gtgcgcgggt cggtgacctc
    13861 ggcgtcgtac tccgggaagt aggagatcac cggatcgtcc aggctcatca gtccctcggc
    13921 gacggcgaac ccggccgccg tggaggtgaa gctcttgctg agggagtaca gcagctgggg
    13981 ccggtcgggg gcgcagggcg cccaccagcc ggcggccacc aggtggtcgt ggcgcaggat
    14041 catcaggctg tgcggctcga tgtcggggtc ggactccagg gcgtccagga aggcgtgcac
    14101 acgggaggag tcgacgccct gggccgcggg cgtactggtg aggagcgcgc gtgtcgtcat
    14161 gccgtcatcc gtacccgccc cggcggatcg ttttccccga cgcgggccgg ggactcgggg
    14221 cccatggtgc agatcggata cacgatgatg accgagcagg ccggcccgcg tgacctcgtc
    14281 gaccacgtgg tgcgcgccga ggaggccggc ttcgacttct ccgtgacctc ggaccactac
    14341 tttccgtggc tgcgcgcgca ggggcactcg ccgtacgcgt ggagcgtgct cggcgcggcc
    14401 gcacaggcga cccggcggat tccgctgatg acgtacgtga cctgtcccac gttccgctac
    14461 cacccggcgg tggtggcgca gaaggcggcg acggtgcagt tgctctccga ggggcggttc
    14521 cggctggggc tcggctccgg ggagaacctc aacgagcatg tggtgggcgg gggctggccg
    14581 tcggtggagg tgcggcacga gatgcttgag gaggcgatcg ggatcatccg ggcgctcttc
    14641 gagggcggcc atgtctcccg gcacggcacc cattacgacg tggactccgc ccggctgtgg
    14701 gacctgcccg acccgccgcc gccgatcggc gtcgccgtct ccggggagcg gtcctgcgcg
    14761 ctggccgggc ggctcgcgga cctggtgatc gccaccgagc cgaagccggg gctgctggac
    14821 tccttcgacc ggctcggcgg gagcgggaag ccgcgggtcg gccagttgcc ggtctgccac
    14881 gacgccgacc gggacaccgc ggtcaggcgt gcccacgccc agttccgctg gttcggcggc
    14941 ggctggaagg tgaactccga gctgccgcac ccggattcct tcgaggcggc cacccagtac
    15001 gtcacccccg acgacgtcgc cgccgcgata ccgtgcggcg acgacccgga cgacttcgtc
    15061 gaggcggtac ggccctatgt cgaggccggg ttcgacgagg tggccctggt gcagatcggc
    15121 ggggagtcgc aaccggccta tctggactgg tcggagaaga ccctgctgcc cgctctccgg
    15181 aacgccttcg gatgacacgc ccccggggcg gtcaaaccgc cgcatgcggg cgcatatagg
    15241 ctgcctgtct gcacttgcgg ttccagcctc aggagagtca tccgtgaccc tagccctcgt
    15301 cccgtccgag acgtcacccg tgcccctgtc cgacctcgtc gcgcgggacg cgcgtgagtt
    15361 cggggcgtac gcgcgcaccg gcggctgggc ctttgccctg atggtggcgc ggagcgtacg
    15421 gcccggcggc cagggcgccg aggagacgcc gaaggtgtcc gcgaaggagt tcgcggagct
    15481 ggcgggctgc tccccggagc gggtcatgcg ctactacagg gcctgggacc gggccgccga
    15541 cgacggcctg gtcccgcagt tcgaggcgct ccggccgggc gccgaggtgg aactgccgga
    15601 cgcggacgtg tggctgagct actacgtctc ccgcaacagc gccacctccg agcgcggcac
    15661 cgcgatcgcc gaggcggccg aggcggaggg catccggccg acgaaggcgc tggaggtcgc
    15721 ggagaacccc accgcgctgc gcgcggcgat cctcgccgac ccctccaccg cccgcgcggc
    15781 ccgcagcgcg ctgctcgacc gcgtcaagga ggaccccgag ctccaggtcg agctggcgcg
    15841 ggacgtggtg cgcaccgacg atctgaagaa ggccgtcgcc agtgagagcc gggccgccga
    15901 ccggatcggc tatgtccgcc agatcgccga gtcggggcag gtgaagacgc ctgccgggca
    15961 gaccatcgag gcgcccgtgg aactgcgcca ggaggccgag cggcatctgt ccctcatcga
    16021 cgagctggac gaggacgagg acaccggcga gtgggccacc gaggcctacg acaccctgcg
    16081 cagcctcgtc gccgagaccg tggaggccga ccccgaactg cgcgtccagg aacgccggac
    16141 gaagttctac agcagcctcc agcgggccac gaaggtgttc gaggagctga ccttcgacga
    16201 tgtgcaggag ttcgccgagg acgacatggt gcggcagctg gaggacctcc agcaggccat
    16261 cacctcgtgc atcgccgcgc tgaagggcgg tcagtcccgc gaggtgtagc ggcgcctgat
    16321 ccaccagccc aggccgaacc agcacaccag gtaccagagc acgatgccgg tgacgatcca
    16381 gggcacatag ccgtcgtggg tggcgacccg gaggatcagc agcagcgagg acgccatggt
    16441 gatcagcagc agcaccaggc cgatgaaggt gagccgggag gcccattcga ccgcgcgcgg
    16501 tttgatgcgc ctcccggaca ctatgcggtg cagggacacc ggtccgatga gggcgccggt
    16561 ggcggcggcg cccaccacca ccgtcaccag gtagatcgtc ttctcggtgt ctccgaggtc
    16621 gtcgtacttc ggggtgaaga cgacggtgag caggaaaccg aagaggatct ggacgcccat
    16681 ctgggcgacc cggacctctt gcatgagctc gccccacatg cggtcggcac gctcgtcctc
    16741 ggtctcgttg cggccggtgc gtttcgcggg ttcctgcgtc gccatacggt ccgggtctcc
    16801 cggtgttgat ccttcaaaca gttaccagcg ggcctcgacc tgctccttga tccgccgctc
    16861 gtacagctca cggatcgcgt ccagggtctc ggcggacagc tccggcagcg cggcggccga
    16921 ggcgttggcg cgggcctgct cgggtgagcg ggcgccgggg atcaccgtgg tcactccggg
    16981 ctgctggacg atccagcgca gggcgagctg ggccggggtg aagccctcgg gggcgagggc
    17041 ggagaactcg gcggcggctt cgacgccggt ggcgtagtcg acgccggaga aggtctcgcc
    17101 ctggtcgaag gactcgccgt gccggttgta ggtgcggtgg tcgttctccg ggaagacggt
    17161 gtccttggtg tacttgccgg acagcaggcc ggaggcgagc ggaacgcggg cgatgatgcc
    17221 gacgcccgcc tcccgcgcgg cgggcaggac ctcgtacagg ggcttcatcc ggaacgggtt
    17281 gaggatgatc tgcacgctcg ccacgcccgg ccgggcgatc gcggtgagcg cctcggcgca
    17341 ggtctccacg ctcacgccgt aggcggcgat gcgctcctcg gcgacgaggg tgtcgagggc
    17401 gtcgaagacc tcgtcgctgg agtagacggg ggtgggcggg cagtgcagct gcaccaggtc
    17461 gatccggtcg acgccgaggt tgcggcggga acggtcgttc caggcccgga agttgtccag
    17521 gacgtagttc tcggggatct gctcgacccg gcggcccatc ttggtggcga ccatgacatg
    17581 caggtccgga cggccgctga ggaacgcggc gatggtctgt tcgctgcggc cgtcgccgta
    17641 gacgtcggcg gtgtcgaaga aggtcacccc ggtctcggcg gccgtctcca gcaccttgag
    17701 ggcttccttg tcgtcgacgt cgccccagtc ggctcccagt tgccaggtgc cgaggccgat
    17761 gacggaggcg tgctgctgcg acctgctgaa tgtgcgctct tccatggcgt cagtctgtca
    17821 cccgcgcgag cttcgggccg agccagcgct tcaggcggcg cagtgcctcc agccgccccg
    17881 ccgcccggtc caggcggtag tagagctgcg gcgggacgta cggcagcagg ggtgagtggc
    17941 gctggcccag cagggcgaac atctgctccg gcgggaggtc gatgtagcgg gtgaggttct
    18001 cgtaccactg ggcgctgtgc cgggcggcgc tctgcagcgg gagcagttcc tgcttgcgtg
    18061 cgcgttcgta gtgggcgagg gcctgcggga ggtcggtgtg gtcgcgcagg gcgccggcca
    18121 gggcgagggc gtcctccagg gcgagggtgg tgccggcgcc gatggagtag tgggtggtgt
    18181 gggcggcgtc gccgagcagg acgaggttgt cgcggtgcca ggtgcggttg gtgagggtgc
    18241 ggaagtgcag ccagggggag ctgccgtcgg ccggtgcccg gccgatcagg gcgtggccgt
    18301 cgagggtgtc ggcgaacagc ttctccagca gcacgagccc gtcggcctcg tcggcccggt
    18361 ccaggccgag gccggtgaag gtctcggggg agcactcgat gacgcaggtg ctgcgctcgg
    18421 ggctgaatcc gtagccgtag gcccagatcc agccgtgctc ggtctcgacg aaggagaagg
    18481 tgaaggtgtc gaagaccttg ctggtgccga gccagatgta gtggttgcgg cccggagtga
    18541 gccgggcgcc gaaatgctcc gcgtgccggg tgcgcagggc gctgtgcacg ccgtcggcgg
    18601 cgacgacgag gtcggcctcg gggagcggcc cgtcggcgtc gatctcgtgc gcgtactcca
    18661 ggtggacgcc gagggagcgg gcgcgggcgg cgagcagttc gagcagccgg tggcggccaa
    18721 tgccgaagcc ctggtcgccg cggtgccggg tgacctggtc gcggacccgg gcgacgcctt
    18781 cgttccaggt gaccgagtgg tcggcgatcg cccgggcgga gacggggtcg tgcatctgca
    18841 gtttgtcgag cagtccgcgc cagtaggtga cgccccagcc gtaggtggag ccctccgggt
    18901 tgcgctcgta cacggtgatg tcgtgggacg ggtccgccag cttcagcagg atcgacaggt
    18961 acagcccggc gggccctccg ccgacacaga cgaccttcac gcgcgcccct cggtatcact
    19021 cgtagcgatc attgcgagac ggagagtagc agcgcgcgga ggcgagtccc ggcttccgga
    19081 tcgcgtcact ttcccggcgt gacgcaggcc acgagccgtg cgcccgcccg tcaagaacca
    19141 cccgaatcgg gggcccgagg agaaggaatt acccgttccg cgcgcacgcg gcatatgcgt
    19201 ggagcaagat catcttggtt caaccttaca ccacatgtgg gtaattgtcc ggatcacagc
    19261 caaccactcc ggaccgattt ctccccatct cggcggcccc gataggcata cggaagtcac
    19321 cagcccacat ccgaaccggg agatccgtat gcccgaactc acccgccgcc gcgcgctcac
    19381 ggccgctgcc gcactcgccg ccgcatcggg ggccgccacc ctcgccgccc ccgccgcacg
    19441 ggccgccggt caccaccccg acccctcccc cgcggccttc gacgaggtct acaagggccg
    19501 ccggatacag ggccgggtgc gctccggcgg gggccaccac cacgaccacg gcggcggcta
    19561 cggcgtctac atcgacgacg tggagctgca tgtgatgcgc aacgccgacg gcagctggat
    19621 cagcgtcgtc agccactacg acccggtggc caccccgcgc gccgcggcgc gggccgcggt
    19681 cgacgaactc cagggcgccg agctcctgcc gttccccgcc aactgaaccg cccctcacgc
    19741 actacctgga gcatccgcac atgaccgtcc gcaagaacca ggcgaacctg accgccgacg
    19801 agaagcgccg cctcgtcgcc gccctcctgg agctcaagcg cagcggccgc tacgacgact
    19861 tcgtccgcat ccacaacgac ttcatcgtcg gcgacaccga caacggcgag cgcacgggcc
    19921 accgttcgcc gtccttcctg ccctggcacc gcagattcct gctggagttc gaggccgccc
    19981 tgcaggaggt ggacgcctcg gtggcgctgc cctactggga ctggacgacc gaccgcacac
    20041 cgcgcgcctc gctgtgggcg ccggacttcc tcggcggcac cgggcgcagc ctggacgggc
    20101 gggtgatgga cgggccgttc gccgcctcga ccggcaactg gcccatcaac gtccgtgtcg
    20161 acggccgcac ttacctgcgc cgctccctcg gctccggcgg ccgtccgctg cccacgcggg
    20221 ccgaggtgga gtcggtgctg gccatcgaga cgtacgacat gccgccctgg aacagcggtt
    20281 cggacggctt ccgcaaccac ctggaggggt ggcgcggggt caacctgcac aacagggtgc
    20341 acgtctgggt cggcggccag atggccaccg gggtctcccc caacgacccc gtgttctggc
    20401 tgcaccacgc ctacgtggac aagctgtggt cccagtggca gcgccgccac ccgaactcgc
    20461 cctacctccc ggcgacgggc acgccggacg tggtccacct caacggcacg atgaagccgt
    20521 ggaacaacgt gcggcccgcc gaactgctgg accacacccg gcactacacc ttcgacgtgg
    20581 cctgaccggg ctcacgcctc ggcggtacgg cactccgggt ggccccagcc ctgcgcgttc
    20641 ttggcgatct gctcgcccgc cgcgtaggag cggccgcaca cacagcggcc ggggaacttc
    20701 gccttgatgg tgcgggcgga ggaaccgccg ccgctcttct tcgcggccgc ggggcggcgg
    20761 cgcggcgcct tgacgggggt gtccggggag ggcggcggct cgggtgagcc cagctcgctg
    20821 cccgcgggct cctgcacggt ggcggcctgg ctggcggcgc ggtccgcgaa gtcgttcagc
    20881 ttgtcgccgt cgacctggtg ggcggggacg tagcggaact ccaccgaccg tccggccagg
    20941 agttcgtcga tgcgtacgac gagctcctgg ttggcgaccg gcttgccggc cgaggtcttc
    21001 cagccgttgc gcttccagcc gggcagccag gtggtgaccg ccttcatggc gtactgggag
    21061 tccatccgga cctccagcgg cacctcgggg tcggtggccg ccaaaaggcg ctccagcgcg
    21121 gtcagttcgg cgacgttgtt ggtggccctg ccgagcggtc cggcctccca gcgggccggg
    21181 gtctcgctct cgtcggcgac gacccaggcc cagcccgcgg gtccggggtt gcccttggaa
    21241 gccccgtcgc acgcggccac tactcgttca cgcatgtgcc gatcatgcca cgggcccgag
    21301 ggtgccccgg tcagacgtcg gtgagcttgg gcatctcgcc ctcggtggtg gtgacgtcga
    21361 tcaccgagaa gttcgcgccc tgcgggtcac tgagcgccgc gatccggccg aacggcgtgt
    21421 ccaccggccc gaaccgcagc accccgcccc gctcggtcgc cttcgccacg gtcgcgtcga
    21481 cgtcggggac ggagaagtag acgttgatgt aggccggtac ctccggcggg aactcctccg
    21541 tcatcttcat ccggccgagg acgggggtgt cggcgatgtt gaagacccgg aagtccatgc
    21601 cgtcgtcctc catctgctgc gcggtgtagc gcgggaagac ggccgggaag aaggcgtcgg
    21661 acttgtccgg ctcccgggtg aagacctccg cccaggcgaa cgcgccgggc tgctcgggcg
    21721 gtgcctcgaa gccctcgtgg gtgccggcct gccagacacc gaagacgact ccgctcgggt
    21781 cgcgggccag gcacatggtg ccgaagtcac tgacctgcat cggctccatc agcacctcgc
    21841 cgccgttgtc ccggatccgg cgggcggtct cggccgcgtc cggggaggcg aggtacaggc
    21901 accactgcga catgccctcc tgtccgggca tgggcgggac gaccgcggcg gccgccttgc
    21961 cgtccgcgta cgcctgggtg tagttgccga actccgacga cgactcgccg aaggtccagc
    22021 cgaggacgtc tccgtagaag ctcttggctc cctcgaagtc gctgaacatc gcgtcggccc
    22081 aacagggggt tccctctggc tgtacggcca tgaccacggc ctcttccgca tcggtggtgg
    22141 ggtcggtacc tcacgctagc cacccgtggc gcgaaccgcg cgccgaaggc agccgtccgt
    22201 ttcacactgg gaggaaaggg tccagtggca ggacggggca gccctatggc ggacgggacg
    22261 atgcgcgcgt ggtcggtggt ggcgcccgga ccggtggagg aaggcgcgct gcggctggtg
    22321 gagaagccgg taccggcgcc cggggacggg gagctgctgg tccgggtgct ggcctgcggg
    22381 gtgtgccgca ccgatctgca tgtcacggag ggcgatctgc cggtgcgccg ggcgggggtg
    22441 acacccgggc acgaggtggt cggggaggtc gccgggctcg gcgccggggt cagcggcttc
    22501 acggtcggcg accgggtcgg ggtggcctgg ctgcggtgga cggacggcac ctgcgcctac
    22561 tgtctgcgcg gcgcggagaa cctgtgcccc ggatcgcggt acaccggctg ggacacggac
    22621 ggcggctacg ccgagtacac gaccgtcccc gccgacttcg cccacccgct ccccgcgggc
    22681 ctgaccgacc tggcgctggc gccgctgctg tgcgccggga tcatcggcta ccgggcgctg
    22741 cgccgggcct ccctcccggc gggcggacgg ctcggcctgt acggcttcgg gggcagcgcc
    22801 catctgtgcg cccaggtggc gctcgcggag ggcgcccggg tgcatgtgct gacccggggc
    22861 gctgcggcac ggcggctggc cctggagctg ggggcggcgt ccgcgggcga ggcgcacacg
    22921 atgccgccgg agcccctgga cagcgccatc ctgttcgccc cggtcggcga cctggtgccg
    22981 gtggcgctgc gcgcgctgga ccggggcggg gtgctcgccg tcgccgggat ccatctcacc
    23041 gacaccccgc cgctgcacta cgagaccgat ctgttctacg agaaggaact gcgcagcgtc
    23101 acctccaaca cccgcgcgga cgcacggaag ttcctcaccc tcgccgcccg gtacaaggtc
    23161 cacgccacca cgcacgccta tcccctgtcc cgggccgatg tggcgctgcg ggacctcaag
    23221 gcggggcggt tcgacggggc ggcggtgctc gtcaacgacc tgagctgaca gggcagttgg
    23281 cggtgtctgg ccgacacggg tcttccgcct gcggcgtggc tgtgcttgcc tggggagccg
    23341 tttctccgtt accggggcgg gagttgccgc atgcgcaggg cgtggatggc ggggttggcg
    23401 ctcggagtgg cactgctcgg cggctgcggg gacccggcgt cggagccgga gcgggcaccc
    23461 gcgcccgcca agccccgggc gtcggccacc acccagcaac gggcacccgc atcaccgaag
    23521 gccccggcga aaccccccaa ggtgctctac ctcggcgact ccctggcgat ggaggcgcag
    23581 aacgtgctcg gcgccgagct gcgcgggagg ctgcgcgccg cctacaccag tgccccgtac
    23641 tcgggcacga ccgtctgcga ctacctggag ggcaccggtg agcggtcgct ggtgccggac
    23701 gcggacaagg cggccgcgct ggtgcgcgcg caccggccgg acttcgtggt gctccagttc
    23761 tggggcaact cctggggcta cacgccctgc atggacggca tcacgcacga cgccggtccc
    23821 cgggcctact tcgaccggta caccgcggac ctggaccggc tcacctcgca gatcgccgcc
    23881 gcgggcgggg agcaccgccc gcggatcgta tgggtgctcc agggccccga cccgatcacc
    23941 ccggaccggg tgcggaaggt gaacgccctg tacgaggagc gggccggcgc ggcaggtgac
    24001 ctcgtcgcgg acgcgggacg gacggtgagc gccgacgggg cccgctacac ctgggtgcgg
    24061 cagctgccgt gcaccgccta cgagcgcgcg cacccggact actgcaccga tccgggccgc
    24121 gaccgcaccg ccctgcaccg cgaggacgac tatctgcact tctgtctggc gcccaccacc
    24181 tcgaccccga agccgtgccc ggtccgctcc cccggcatcc tgcggatggc ccaggaggtc
    24241 acccgggtga tccgcggcgc ccggtgagga cggggctcac tcgccgtcgt aggccttctt
    24301 cagggcggcg atgtcgagct tgcgcatgcc gagcatggcc tgggtggcgc gggacgcctt
    24361 ctccgggtcg gggtcgctga ccatggcgtc caggctctcc gggatgacct gccaggacac
    24421 cccgtacttg tccttcagcc agccgcaggg gccgggctcg ccgccgttct cggtgagctt
    24481 cgtccagtag tagtcgatct cctcctggtt ctcgcagtag atcatgaacg agatcgcctc
    24541 gttgaacgtg aaatcgggtc cgccgttgag ggcgaggaac gggtggccgt tggccgtgaa
    24601 cgccaccgtc atcaccatgc cggccgggcg catggagccc tcggggtagc gggcgatgct
    24661 gccgatgctg gagttcttga agacggagac gtagaagtgc gcggcctcct cggcctggtc
    24721 gtcgaa
//
