LOCUS       NZ_CP104098            25151 bp    DNA     linear   CON 08-NOV-2024
DEFINITION  Streptomyces noursei strain IFO14147 chromosome, complete genome.
ACCESSION   NZ_CP104098
VERSION     NZ_CP104098.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces noursei
  ORGANISM  Streptomyces noursei
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9223378)
  AUTHORS   Zeng,X.
  TITLE     Transcriptome and Metabolome Analysis Revealing the Improved
            epsilon-Poly-l-Lysine Production Induced by a Microbial Call from
            Botrytis cinerea
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9223378)
  AUTHORS   Zeng,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2022) College of life science, Huaibei Normal
            University, Dongshan road 100#, Huaibei, Anhui 235000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: PGCGAP v. 1.0.34
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025163575.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 12:09:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,195
            CDSs (total)                      :: 8,101
            Genes (coding)                    :: 7,883
            CDSs (with protein)               :: 7,883
            Genes (RNA)                       :: 94
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 218
            CDSs (without protein)            :: 218
            Pseudo Genes (ambiguous residues) :: 0 of 218
            Pseudo Genes (frameshifted)       :: 93 of 218
            Pseudo Genes (incomplete)         :: 149 of 218
            Pseudo Genes (internal stop)      :: 11 of 218
            Pseudo Genes (multiple problems)  :: 33 of 218
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:04:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8843866
            Orig. end                         :: 8869017
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP104098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25151
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="aureonuclemycin"
                     /region_number="34"
                     /rules="(her4 and her5 and her6 and her7)"
                     /tool="antismash"
     cand_cluster    1..25151
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(her4 and her5 and her6 and her7)"
                     /kind="single"
                     /product="aureonuclemycin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25151
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:15151](-)"
                     /cutoff="10000"
                     /detection_rule="(her4 and her5 and her6 and her7)"
                     /neighbourhood="10000"
                     /product="aureonuclemycin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15151)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(her4 and her5 and her6 and her7)"
                     /neighbourhood="10000"
                     /product="aureonuclemycin"
                     /protocluster_number="1"
     misc_feature    complement(166..181)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.3"
                     /tool="antismash"
     misc_feature    169..184
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.51"
                     /tool="antismash"
     misc_feature    complement(219..234)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.58"
                     /tool="antismash"
     misc_feature    complement(237..252)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     misc_feature    610..628
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.56"
                     /tool="antismash"
     misc_feature    complement(705..718)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.42"
                     /tool="antismash"
     misc_feature    complement(814..825)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.45"
                     /tool="antismash"
     misc_feature    complement(997..1017)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    1181..1195
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.65"
                     /tool="antismash"
     misc_feature    complement(1183..1194)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.78"
                     /tool="antismash"
     misc_feature    1741..1750
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.02"
                     /tool="antismash"
     misc_feature    1882..1895
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.28"
                     /tool="antismash"
     gene            2065..2271
                     /locus_tag="N1H47_RS38815"
                     /old_locus_tag="N1H47_38810"
     CDS             2065..2271
                     /GO_process="GO:0061077 - chaperone-mediated protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012314.5"
                     /locus_tag="N1H47_RS38815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_38810"
                     /product="co-chaperone YbbN"
                     /protein_id="WP_260222787.1"
                     /transl_table=11
                     /translation="METTAQNYGSRLTVAYLDNDQNPAALKKYNPSGIPAFYLFKNGQA
                     VSYRIGYYTAAQIKEWLRSNGVA"
     gene            complement(2430..>2952)
                     /locus_tag="N1H47_RS38820"
                     /old_locus_tag="N1H47_38815"
                     /pseudo=""
     CDS             complement(2430..>2952)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019984222.1"
                     /locus_tag="N1H47_RS38820"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="N1H47_38815"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="AQSVKTSTGVPAAVRALTRGRRSWAASAASSPIPSACCWRLLSRP
                     RVCRAQWPAHTWSTPWPPPIPPFGKSGWTAATASISSNMQPAWASTWKSFSAPPEPEAS
                     PHPEAMGCRTHLWMADAPPPPGTRLRSPPRTLRSHDPPGHDRPHGPPPHRRSHHLLAQL
                     HKPASTTESRM"
     gene            complement(3185..4327)
                     /locus_tag="N1H47_RS38825"
                     /old_locus_tag="N1H47_38820"
     CDS             complement(3185..4327)
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013345.5"
                     /locus_tag="N1H47_RS38825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_38820"
                     /product="alanine racemase"
                     /protein_id="WP_037635182.1"
                     /transl_table=11
                     /translation="MTTDKGRARLPELRLDRGTLEHNVQVMAAWCRNHRVELAPHIKTT
                     MTRPVVERQLSAGAWGVTVATVAQAAIALEWGARRVIVANQVIHPTDLEIVRQWLGEVS
                     DLELYCFVDSTTGIDLAREALAGAASPLRILIDIGTEGGRTGVRDPATAGALARDVHAA
                     PELLLAGVAGYEGIRSNLRDAATLAAVDEHCRTAIKVFRNLASLFEVTQPVFSMGGSAF
                     PDRVVRAVAAYLQRPDALGMVPVLRSGCYVTHDHGTYEHVSPVPDLKPALTVRAVVLST
                     PEPQRAVIGAGRRELPYDAGLPVLVRAHDAHGAPRPSAAATASQIYDHHLVLTQAHGLR
                     VGDQVDLGISHPCSAFDRWPGITVVDGDDRTDEVWHPQFH"
     gene            4473..5066
                     /locus_tag="N1H47_RS38830"
                     /old_locus_tag="N1H47_38825"
     CDS             4473..5066
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF019498.5"
                     /locus_tag="N1H47_RS38830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_38825"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_016579251.1"
                     /transl_table=11
                     /translation="MSTEESVPAAPGTSENNGIGQHLRRERLARGLTLEKLAEKTGLSR
                     SYLSNVEREVNSPTINTLRTIVDALGTTLSRLFRELDREPSVLTRPDQRVELTRAGVPG
                     VTYALLNPKHGGQLEMMLLEVAPGASSGDNPHTHGGEEVGLLLSGELDYWIAGVQYHLT
                     PGDCVSFNSSVPHRYSNPGDIPAVCVWSETPPGR"
     misc_feature    complement(5618..5632)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.98"
                     /tool="antismash"
     misc_feature    5619..5633
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 24.07"
                     /tool="antismash"
     misc_feature    complement(5674..5685)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.59"
                     /tool="antismash"
     gene            5686..6036
                     /locus_tag="N1H47_RS38835"
                     /old_locus_tag="N1H47_38830"
     CDS             5686..6036
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N1H47_RS38835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="N1H47_38830"
                     /product="hypothetical protein"
                     /protein_id="WP_124428011.1"
                     /transl_table=11
                     /translation="MGVMMSIKLAASSAVRKAATCGALAVAALTLSAAPALADAPTVVK
                     GPDARGDISYAACPGGTHLIGGGYSWNPIYTNGGSPSDTVDINSPSGAKANTWAAKAHK
                     GVIAAYALCAKD"
     misc_feature    complement(5695..5708)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
     gene            complement(6056..6343)
                     /locus_tag="N1H47_RS41560"
     CDS             complement(6056..6343)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039695.4"
                     /locus_tag="N1H47_RS41560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6233 domain-containing protein"
                     /protein_id="WP_368730780.1"
                     /transl_table=11
                     /translation="MWRRPRTPPHAPPVTPPAASSSRVTDSTTSPGSRSVPPGLISDVR
                     LLPCPGPGQPCPVARSATAGDCSLAGRRARPNSREHAIRALTEGLEPCTL"
     gene            complement(6366..7466)
                     /locus_tag="N1H47_RS38840"
                     /old_locus_tag="N1H47_38835"
     CDS             complement(6366..7466)
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016579249.1"
                     /locus_tag="N1H47_RS38840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_38835"
                     /product="methyltransferase"
                     /protein_id="WP_016579249.1"
                     /transl_table=11
                     /translation="MTTPQPEAAFPADSPHAIIDVAVAFWKSKALLSAVELGVFEELAV
                     RPATRAELTGRLEIAGRGAADFLDALVSLGLLERDGGVYRNSPVADRYLDPRKPATDIS
                     GYLSFLNAGFGCWAGLTDALRSGGRLDFSAALAASRSADQGGAGDPKLVGADATDDTFG
                     EAYAAPDQVTGFLRAMTGYSMGANQAIAERYDWSRSRTVADVGCAEGSLLAQVLSRNPH
                     LQGIGFDLPVVGPGFDAHLERVGLTDRACFAGGDFFTDPLPTADAIVMGHVLHDWDLDT
                     KKTLIGKAYEALPEDGRLLVYESLIDDDRRERTTGLLISLNVSTVSAGGLGYTGAECGD
                     WMRAAGFRDIAVSHLDGPEYLVVGVK"
     misc_feature    7437..7446
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(7525..9147)
                     /locus_tag="N1H47_RS38845"
                     /old_locus_tag="N1H47_38840"
     CDS             complement(7525..9147)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004941300.1"
                     /locus_tag="N1H47_RS38845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_38840"
                     /product="serine hydrolase"
                     /protein_id="WP_020930509.1"
                     /transl_table=11
                     /translation="MSAACTAPHGSGTAAPAAHPLFSREWLRHAEAAAGQRPEAGEALR
                     LGLRLTDPPVGVAGQILVLTDLATGALWFRAGEWDERPTLVLTLRHEEAAVLLFGDGER
                     RVRLFEHGRLVLEGVFLFIFFLDRLLQQDPSGALARLRGFTADPPQAAGPWPGAAAAVT
                     APDAEADAVRAATEALPRTMAALRTELGRTTPGAQLHVSHAPSGTTVSAALGSCRPGVP
                     FTRASLPIWYCCSKTLGAVAIGQLWERGLLDPAAPVARYLPWYDGDGRERVTLYQLLTH
                     TSAVPMGLDPLHGAMAAPVALRREQLRNMTVPAGTPPGARINYGPWWAWFLIAEVVRAV
                     DGRDYERYLAEEILAPCGMTDTRVVLTPQEYRAEADRLPLIHITGGGLPAQPTHWYATE
                     SSCTRPIPGLNIRGPMSDLALFFAALAEGGRGRHGRILLPQTVMALTAHHRVGLVDPFG
                     NADWGLGFRVESRHLGDECTAFSRHASPRTFGHYGLWTSAAFADPDAGLVVALHLNGKT
                     WQEEHQERMITIGDAVYQDLRLT"
     gene            complement(9144..10004)
                     /locus_tag="N1H47_RS38850"
                     /old_locus_tag="N1H47_38845"
     CDS             complement(9144..10004)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576689.1"
                     /locus_tag="N1H47_RS38850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_38845"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_016576689.1"
                     /sec_met_domain="PCMT (E-value: 6.7e-09, bitscore: 34.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGTLRHPAPDEHKQALARLFDRSAPTYEKVGVSHFGALGRQLVE
                     EARVREGERVLDVGCGTGAVLVPAARAVGPSGSVTGIDLSAGMVERSRAAIADEGLGNA
                     RALVADAETAHWQPGPPVDGTFDAVLAGISMFFFPHPRAAAARYRRLLADGGRFAISWW
                     GRQDERWNPVFAASAPYGGASSHRLPPDSPFRSVEDLHAMLSEEGFSSVDTVERTCVTR
                     FRGPHQWWQWVWSTAGRQFWESVPEDAMTDAVKAVDAELAELRAPDGSLTSRNIVRFTV
                     AEVAR"
     gene            complement(10001..11113)
                     /locus_tag="N1H47_RS38855"
                     /old_locus_tag="N1H47_38850"
     CDS             complement(10001..11113)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aureonuclemycin: her7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576688.1"
                     /locus_tag="N1H47_RS38855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_38850"
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_016576688.1"
                     /sec_met_domain="her7 (E-value: 1.2e-208, bitscore: 691.5,
                     seeds: 189, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.5e-23, bitscore:
                     82.6, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 6.4e-29,
                     bitscore: 99.3, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRFGILGCGSIGGFLGRLLARPDGPLRERARLVAVAGRDPVRAH
                     RLAAELGCEALAVPELLARTDIDAVAVCTPSGTHAELGTAALRAGKHVLVEKPVDVTPE
                     AADRLIAAARHTGRTLGVISQHRFDPAAEVARAAIEDGTLGRITSVLIEVPLWRARSYY
                     ASGQWRGTRALDGGGALMNQAVHAVDLAQWLAGPVVEAAAHTGLLAHDGIEVEDVATAS
                     LKFADGALGALLATTAAYPGRPTRVAVNGERGSVVIDNDELAYFHTAREGERPTAYGAY
                     GDGNQAADRCPPPREPPPRDRIGLLHQPHRDQLADFCDAVRTGRPPLVDGAAGRRAVAV
                     VHAVYTSARTGRTVRLDESGNLTQDKGRTP"
     gene            complement(11124..12431)
                     /locus_tag="N1H47_RS38860"
                     /old_locus_tag="N1H47_38855"
     CDS             complement(11124..12431)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aureonuclemycin: her6"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004941308.1"
                     /locus_tag="N1H47_RS38860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_38855"
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="WP_020930510.1"
                     /sec_met_domain="her6 (E-value: 2e-253, bitscore: 839.6,
                     seeds: 189, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRICLVIPSNKFDQYFIQLPLDAVTAAGHLRAEGHTVTVWDQRL
                     QEAPDGEEFDLLVVFSAIADRAQCYPLELDSVRAAVERAASRYPTARTVAVGPHGTHLP
                     ASTRDELGVDHIACGETDSATVGAVRALLAGADAPVLPGATTPHNLLDSPEPRPRPFPN
                     LPLEELAFPAYDLVPTADYTAEVISGGLPLPGPCGMVLAARGCTYGCTFCHLPFGTKMR
                     NQPLDRVVREIEAQQAAGLEFVFFLDYVFGINRAFYSELCARLEGRGVGWVGQTRAEVV
                     LKNDVTAWARAGCQGMWLGAESPAIADTGVHKRVSEAQIEEAVLKLRDAGITPFAFVLL
                     GLPQDQACISGRLVDWAAKLPAWFGINQLYLRPGTTLYDQLAPQYNGGVLPATWREVQE
                     VTRRYRAAYPTDLDHQQQLLTELPNYLGNTIAPVAG"
     gene            complement(12445..13566)
                     /locus_tag="N1H47_RS38865"
                     /old_locus_tag="N1H47_38860"
     CDS             complement(12445..13566)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aureonuclemycin: her5"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004941309.1"
                     /locus_tag="N1H47_RS38865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_38860"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_037635184.1"
                     /sec_met_domain="her5 (E-value: 5.7e-183, bitscore: 606.9,
                     seeds: 189, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGRPHVCVVGHGVAGRLHHQLLDGMGMSVSVVDPTAPGCGAPFP
                     TAATVGELSTDRPVDVWSVCTPTAGHVQAVAAVLARDPEARILLEKPACRSWEGPELTA
                     LLGAYDRARLVVMNQYAHAKAPAMLEAVRAEFAPRHPVAAIRIAFCKDRREDIAAGRFV
                     DLDYGVFGYEWLHMLAVLGGFLPTRAFHHYLLAGPEPQAVRIARDPHLVSTAAHDTTTL
                     SAGAGPAGEVEVELYSTIVGPDAPHAAPAPSWARRTAPAADSRLRLARIEAGPVLLTLE
                     LDPVFLPNGTRLPRNTHRLTMDGPHGHREWLIPDSPMDNALRHGIAALLGPGPRPALDL
                     RPLDRIGRLAELARAEHPAPSGPLTPAALPTRL"
     gene            complement(13556..15151)
                     /locus_tag="N1H47_RS38870"
                     /old_locus_tag="N1H47_38865"
     CDS             complement(13556..15151)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aureonuclemycin: her4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004941311.1"
                     /locus_tag="N1H47_RS38870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_38865"
                     /product="hypothetical protein"
                     /protein_id="WP_236664455.1"
                     /sec_met_domain="her4 (E-value: 1.1e-285, bitscore: 947.4,
                     seeds: 189, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEGPLGIGDLLAAVRAVLDGHGGAPARPELTVHGPGQYTVRVGG
                     DRLDIRSRPLSDQPPGTLDPVLDGPGVRRIVLTASDTPSERARDLFTALTEAIGRRARC
                     YTEAEAAAIAAGMPLTGRYAQPEPALAGWALIFRDHYVENSVGFLLAMERAGLDPEWIF
                     ALSKGDRTQHRERVHSWFLRRGYASDTLDNSVINGTAGAAETARARAVDAQVADFVRRA
                     HVAGRKVLVIDDGGLLAQGYGADRPGARVDAAIELTVSGLKRITAAPGELAIPVLNMAR
                     SQLKSRLGYNEIADSCVRRLRAIVPGQKFIGRHVLLLGYGTLGARAARSLRALGCRVAV
                     VDTDILALITAAEDGFETHRSIAEALDRQRPFLILGSSGGTAVTAEDVPLLPDGVLLAG
                     FATKDFSVLTDGYPGATAQRIPHVGVRYDLPHATTATVLGDGRSLNLFEYEGIANRGYD
                     AYRAGTLLAALALCRDPERFPPGLHLEPVDSIIDDAGLFDAYYTQYLCARSAPLGTGAF
                     SGTAETSGEDAHAR"
     gene            complement(15414..18167)
                     /locus_tag="N1H47_RS38875"
                     /old_locus_tag="N1H47_38870"
     CDS             complement(15414..18167)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.5"
                     /locus_tag="N1H47_RS38875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_38870"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_020930514.1"
                     /transl_table=11
                     /translation="MGSVLLEREEALAAAARAGESARSGVGRWLVFGAAAGTGRTALLR
                     EAAGREAAGGAMRVLRADCSPEESGFPFALVRQLFPEDGEVPFADLPAAEEQMVFHRLV
                     TRLARTADRRPVLLAVDDLHDADMASRRWLGYLARRLADLPVLLVLTECREKGTAVLPS
                     ATGTSVVLRPLGPEAVARLVSARGHGSDRAELCIRACAGNPVLVHALLADLREGPLPGS
                     LSELGGSRYRDAIVHWIRARATPWSRRLALALAVAGDGAALLGGALLHEAAGLRPDHRA
                     ASAGASALRRLFSHPLAREAALAAVDPAELCALRGRIARLLDERGAPTADVAAQLLHLD
                     RPGEEWMTQSLEDAAEDAVRGGRVDEATAFLRHALTAPLTPGRRAGLTLRLGALELPGS
                     ADAGIRRLRAALELHADRHERAAVAPALGAALVARGRTATAMRVMSQVGSAVDDGELVR
                     VLQTTAAVMASHDAVAWRNAVARMRELAATAPAAVEPLACGLVTEYEVGTGRLSAAEAL
                     GRVLPRLAAPVDPRLRDGWLGTAATLLQWADRLDEARALAEEALPAPPALPDLTDIGRQ
                     CLISVRAEAALWTGDFRRVIAENAPLLDACAGQGIRMPHLASMVALAHCELGHRAHARR
                     LLAGLDEESADSSWEWNELHYARASLHMAEGNWQAALDDYLSCGRGQSARDFVSPVATP
                     WRSGAALALVGLGQPARALDLAEEELRHARTWGTPRTVSRALRAHAAAVGGRRGLESLG
                     EAATVLRTAPAPVELVETLLDLGHARIHAGNSRKGREDLHEAHALALRLLAPDPTEHPD
                     APATGRLLRATGNALRASGARGTRRHATGSAALTRAERRIVELAAQGQTNAQIGEVLHL
                     ARRTVETHLTNAYRKLGVTRRTQLASRLTGTGTAASSSARSLTASG"
     misc_feature    complement(17583..17585)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(18225..18243)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            complement(<18317..>18412)
                     /locus_tag="N1H47_RS38880"
                     /old_locus_tag="N1H47_38875"
                     /pseudo=""
     CDS             complement(<18317..18412)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558180.1"
                     /locus_tag="N1H47_RS38880"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="N1H47_38875"
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGRVRVARPEGGRPRTRPDRLLGDKAYSASRS"
     misc_feature    complement(18460..18473)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            complement(18925..20049)
                     /locus_tag="N1H47_RS38885"
                     /old_locus_tag="N1H47_38880"
     CDS             complement(18925..20049)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N1H47_RS38885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="N1H47_38880"
                     /product="hypothetical protein"
                     /protein_id="WP_016576640.1"
                     /transl_table=11
                     /translation="MAIVTQQRVGNGTASDFTGEIDWSIDTVPDPVTVSPASGSVELAD
                     IILVGSRSIPGEIQVSQIDVDIDHGNEAWHLALDLGGIQASNNLGWTHTVSGNRITFKP
                     TSGHAVIDNERGITLQVNKLRISRKVGTGAVIIGTKWRANESSGWRTDEAVKAVGKFPP
                     GFYLDNFKADPLIIENGDSVTLTWDRSSGATQTLLYENAEIDVTDYTKFEVKNLSRNTM
                     FYLRSRVQQGTDYAERVLNTYVTVNQPDLEIRNLTVRGRVHGNLNADKVTAAVVSEPGS
                     LPWQRKNTITATAGYQTTAPTYGFLQCNNKGNGNYQGTVVLEVGTTGVMSRFEVEARQC
                     STILVKEGDTIKITAVGSVNHETSWYSIGRLAFG"
     gene            complement(20086..23529)
                     /locus_tag="N1H47_RS38890"
                     /old_locus_tag="N1H47_38885"
     CDS             complement(20086..23529)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N1H47_RS38890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="N1H47_38885"
                     /product="hypothetical protein"
                     /protein_id="WP_020930515.1"
                     /transl_table=11
                     /translation="MPARSSNNHLVVPVEVAALAVNARMQNPDGAFVWHRWIANFFHTQ
                     DTAAPAEPSPFSIDADWPARPENRGVYLQWQLPEALTRGRHDTETDEDDFPLVPNRWLV
                     VRYRAASRNVRAWLIESDHLGLDSGTVSALDPRAERTTATKMGRCHELTTSSPWREPGD
                     APTPFLTALGPGLLTFSAFQPYNTNVFSLHDGLDDVAGDERLDYYVAGFYSTPDSDVLD
                     DAEDLRELLDDLEWLAPMAGSNTRRSLYTGSALGVDWQPAGPLPASDIPAVNSIAVSVG
                     NNTAEAATALTDAAAGPGALSDDDSRLVRAFALGTLDALDRADGDDLTDAAAHQSGFGP
                     VPGGFTWRIVERGEDRETGPVRLGARERARTRTAEADIVAALNRAQAEHDGVERDLAAA
                     QDRLYVLWALSNADRQPRDFQNRVDDELDPANQAGAAGKVAALAADLCAKRNALPWGDT
                     PEELEASAAEYARGKGLPPNRVLQRVPKSPFLHVADPVVLLQGGHVHAPLSRDTPLPCR
                     TEDRLVTAVGPIDAAAVRSDVDQVNTANLPAPFTDLLTEFFILARARHTGTGLDDVTGT
                     LPEYGTAAWRQPWQPLFLVWDIECWPLPYSEHDGTRHWTFDGNRYRWQGTGTVPESFVL
                     TGRIPLTPSAGPILEGELDAYAAGRQDLPDLRNLRTQLSDLDMLSQRLEGLTAHLDQRD
                     PRSTARPLEAMGDLIGHGDRHFPVPGTVPSHPSRPPESEPFHEVRTGQFAFRQLSLVDR
                     FGRTLNLIGDNRRWPYVRPDAMVPDHTVETDDPDRFLELSPRLFQPARLAFDFLHATTD
                     QPIDLTPGANPVCAWLLHNRLDRTLACYDPDGQALGELRTVLKPDGTKSVVWLPLPGSS
                     VATLAELEDVAPHAHHFLHALAERGPATFDALRATLDDALTTIDPDSPDDASLGFLLGR
                     PLALLRARLDLELCGPPRTSVGWNEVLDPDDHAPAMPDWKWIVRLGQPRATDDGLVGYV
                     LNDDYAHFDTITPPADGSSGYLRPIDNGERLQLAFAGTSTATVTLLADPRAAVHATTDV
                     LPASAVHIPPAFTDTALARMAVCFRTGPLMAGTTADPRTAVLPHPATASGTWAWAEPTD
                     TQGTWQHLPITAPDPGELPLGDPELRSGYLVLNDAAEATR"
     misc_feature    complement(23870..23884)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.94"
                     /tool="antismash"
     misc_feature    complement(24445..24460)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.12"
                     /tool="antismash"
ORIGIN
        1 ggtgccggac gacccgttcg cacaaccgct gacgacgagc agggacgtga cggtgagcgc
       61 cggtaaaacg gcgtatctga tgctcttgcg cactgttggt tcctcagggg cgtggcgtgg
      121 gggtggccga agggaggaag cactccgacc gggcggttac ccgcaggtaa tgattggcat
      181 gatcgtgcca cgtgtcatac gcccgcagag ccgaacaacc gaccacatgg tgatgatgtg
      241 agcgcaatca cctccgccag agcgctgacc agcgcaaggc tgactcgcgg gggggcgatg
      301 agggcccgtg ggatttctct gggactttgg ggcgcgacgt gcggttcccg ccgctctggc
      361 gccgcctccg cttcctgcgc gtcgcgctcc cacgccgtgc cgccgatggc acaggcaagg
      421 agctgagtcg ctacgcgcaa agcgcggccc cgcagggggc tggcgagagt ccgtcaggcc
      481 gtttgcctta gccaggcgtt gcgaacgttc tgcggagccg gctgcggtca cgccccgctg
      541 gcggcatttc ctgaagagcc gcagtagacg actgccctac cggctggtga gtcatcgggc
      601 atgtcagaag caggttgcgc tcaccgaaca ccctcgctcc gtggcggcaa ttgaccgccg
      661 cctcgcaggt agccgcgaaa aacagccgac gaacaccggt tagccaaatc ggcgtttcct
      721 cggacgatga gatggtcgcc accgagtcgg tgcggcaacg ccacttggcc tgttcttcga
      781 tccctgcgga gctacctcca tgaccgcttg cccgtcagct ttttccccga ttgtcagtga
      841 ccttgtttca ggtaacggtg ccgcgacgct gaggggattt ctgactgtga gcggcgcggg
      901 agaatagctc ggcctttcgc ctcgaacact ctacgtctgg cggcgtcgcc gccagggccc
      961 ccgaactttc gtatgggacc tcgggggcga ctttactgat cctcgcgacg gcgctatcaa
     1021 ggccaaggat tacgttgagt tgcattggtg gcccacgcag agcggggacc cgggaacgtg
     1081 tattggccgt cagggaggtg ttgccgatgc gatatcgaat cctgatcgaa attggccggg
     1141 ctggggctac gtcaaggaga agcgttcggc ctggccctgg aggacatcga tttcacccgt
     1201 gaggtgatcc atgttcggcg tcaggtcaag atcatcggca ctcgaccgtg tttcgcatgg
     1261 tcaaagggta aaagtgtgcg gaaagtgcca cttcctccga gcgttgctgc tgcgctacag
     1321 cgacacatcg acagcaggag gcgctgggag ccggtacctg tccgccctct cacctgggac
     1381 atcatcgggg ccattggtga gcggcagacg ttcagtcaga gtgtgccccc ccgtggacga
     1441 ctgccagcgc gatgcgccgc gcagccgcgc ggagctactg agggcgggga ggcagatatc
     1501 gcagcactcc ccaggaagct ccacgacaac ggccggaatt gaggtgcggg agcgaccatc
     1561 gccgcgggcc cgcccagtga tcgccggcag gggcgagggc gcagtggtcg ctaccgacga
     1621 gcgccgggcg agaagccgca ccgcaaccgg atggccaccc tggcctgcgt cttcgacgcc
     1681 gacctggcga ttcgcttatc tatggcgcga aatctcctaa catgcggcaa ggcactttca
     1741 tgattcttta cctaaggtga tcgcttgagt acccgccgtc gcgtcacggg gtgaaaggcg
     1801 tcgatactcc cggaccgcgt acatgagctg attcgtgttc gcgccgaccg ccctcctggc
     1861 ccgatgtcga acgaggggaa gagaacagag gttcacgctt ctgcggcagg ggccgccccg
     1921 agggccgccg cggcggcagg gggcgtgatc gccactgccg acgccaggtt cgaccgggat
     1981 gcggtggggt ccggcgtccc ggctctgatc gagttctgcg tcggtaggtc ggcctcgtga
     2041 ggacgcatca ggcggacccg ggtactggag accaccgccc agaactacgg cagccgtctg
     2101 acggtggcct acctcgacaa cgaccagaac cctgccgcgc tcaagaagta caacccgagt
     2161 ggcatcccgg ccttctacct gttcaagaac gggcaggccg tcagctaccg gatcgggtac
     2221 tacaccgccg ctcagatcaa ggaatggctc cggagcaatg gtgtcgcctg acctgcccga
     2281 caccagtctt ctcgggccgt gcagcctggc gccccggaac cgtgtgcggg cattccgtgc
     2341 tgccgctcac tcctgtattc ggattccgca gggtcacatc tcttgtcgat cgctcctgga
     2401 aggcgtagat ggaagagcct cccgttgttt catcctggat tctgtggttg atgctggttt
     2461 atggagttgc gccaggagat ggtggcttcg ccggtggggc ggcgggccat gaggtcggtc
     2521 atggccaggt ggatcatggc ttcggagcgt tcggggaggg cttcgtagtc gcgtgccagg
     2581 cggcggtgga gcatcggcca tccataggtg cgttcgacaa cccatcgctt cgggatgggg
     2641 tgaagcctct ggctccgggg gtgcgctgaa cgatttccac gtcgatgccc aggcgggctg
     2701 catgttcgac gagatgctgg cggtagccgc cgtccaccca gactttccga atggtgggat
     2761 gggcggtggc cagggcgttg accaggtgtg tgccggccac tgagccctgc acacccgcgg
     2821 ccgtgacaac aaccgccagc agcaagccga gggtatcggt gacgatgctg cgcttgcggc
     2881 ccacgatctt cttccccgcg tcaacgccct gactgccgcg gggacaccgg tggaggtttt
     2941 cacgctctgc gcgccttcgc ccgcggcctg gaacgagacc gcgacgccgt gatcgccgcg
     3001 ctcacactcc cgtacggcaa cggccccacc gagggcgtca ttaccaagac caaacggatt
     3061 gcgcgctccg tcaccaccga aagtgagaca gggccgttaa gttgacactc cctcttcgaa
     3121 cggatcatgc ccggagcatg gatcctggcg gcgaatgccg gagtggggcg ggtggacttg
     3181 acgatcagtg gaattgcggg tgccacacct cgtcggtgcg gtcgtcgccg tcgacgacgg
     3241 tgatgccggg ccagcggtcg aaagctgagc aggggtggga gatgccgagg tcgacctggt
     3301 ctccgacccg cagtccgtgt gcctgggtga ggacgaggtg gtggtcgtag atctgggacg
     3361 ccgttgccgc ggcggacggc cgcggcgcgc cgtgtgcgtc gtgggcgcga acgaggacgg
     3421 gcaggcccgc gtcgtagggc agttcacgcc tcccggcgcc gatgacggca cgctgcggtt
     3481 ccggggtgga gagtacgacc gcccggacgg tgagcgctgg cttcaggtcg ggcacgggcg
     3541 agacgtgctc gtaggtgccg tggtcgtggg tgacgtagca gccggagcgg agcacgggca
     3601 ccatccccag ggcgtcggga cgttggaggt aagcagccac ggcgcgcacg acacggtcgg
     3661 ggaaggcgga gccgcccatg ctgaagaccg gctgcgtgac ctcgaacagt gaggcgaggt
     3721 tgcgaaacac cttgatcgcc gtccggcagt gctcgtcgac ggccgcgagg gtggcggcat
     3781 cccgcaggtt gctgcggatt ccctcgtagc cggcgacgcc ggcgaggagt agttccggcg
     3841 cggcatggac gtcccgggcg agtgcaccgg cggtagctgg gtcgcgcacg ccggtgcggc
     3901 ctccttcggt gccgatgtcg atgaggatcc gcagcgggct ggcggccccc gccagggctt
     3961 cacgggcgag gtcgatgccg gttgtggagt cgacgaagca gtacagctca agatccgaca
     4021 cctcacccag ccattgccgg acgatttcaa gatcagtggg gtggatcacc tggttcgcca
     4081 cgatgacgcg ccgcgccccc cattccaggg cgatggcggc ttgggcaacg gtggcgaccg
     4141 tgacgcccca tgccccggcg gacagctgcc gttcgacgac cgggcgcgtc atggtggtct
     4201 tgatgtgcgg agccagctca acacgatggt tgcggcacca ggcagccatg acctggacat
     4261 tgtgctccag cgtgccacgg tccaggcgca gttccggcag tcgggcccgg cccttgtctg
     4321 tagtcatgtc gcgatccatc cgatctccaa agccaggagt aggcgcagac acacaggtgc
     4381 gtcgtatata cacgacggag cgtaaaccat tcaggacatc ccctccaaac actatgatgg
     4441 acgcagtgac gtatttactg gaggaggggt cggtgtcgac cgaagaatcc gtgcccgcag
     4501 cgccggggac ctcggaaaac aacgggatcg gccagcacct gcgccgtgag cgcctggcgc
     4561 gcggcctcac gctggagaag ttggccgaga agacggggtt gtcccgcagc tacctcagca
     4621 acgtcgagcg tgaggtgaac agcccgacga tcaacacgtt gcgcaccatc gtcgacgccc
     4681 tcggcaccac actcagccga ctgttccgcg aactcgaccg ggaaccctcg gtgctcaccc
     4741 ggcccgacca gcgagtcgaa ctcactcggg cgggggtgcc cggagtgacc tacgccctcc
     4801 tcaaccccaa acacggcggc caactcgaaa tgatgctgtt ggaggtcgcg ccaggcgctt
     4861 cctcaggcga caacccccac actcacggag gcgaagaagt cggactcctc ctgagcggcg
     4921 aactcgacta ctggatcgcc ggtgtgcagt accacctcac gcccggtgac tgcgtcagct
     4981 tcaactcctc cgtaccgcat cgctacagca acccgggcga catccccgcg gtctgtgtct
     5041 ggtccgagac tcctcccggc cgctgaaggg tcgccccccc gacgaagcgg gccgagggtg
     5101 tcgagcccac gttctgcact ggtcgggttg gggccgcaga cgccaacgcc ggtcccgcat
     5161 cagccactgc gaacgacgcg gccacagctc atgaaactgc ccgaccatca gcgaagacac
     5221 cgttggccta ctagccccga cgcggactcg ggccgcgcgg gccgcaccgc gcctatcgcc
     5281 cagcgatgag cgcgccgcca ggctcgggat gctgcccgca accgaagcgg tgacctggga
     5341 acgcctcaag ctacgtgcct cttgaatgtg gtcgagcatg gagttgcccg aggagtcgca
     5401 ctccgtggtg acgctcttcg cggatgcaga cgcgcgtcag ttgcccgcag cggtagcgcg
     5461 tgaccacctg tttcgaacgg aacaaggggg ccaccgggga tgggggaccg ctgtcagaag
     5521 gcagggaatt cgaacgggaa gccgcggaat gtggcagccg ttcaggctta caggtgactg
     5581 catgcacacc aaggagtgat cgccttgggg gaggggcctg ggagcgcttc cggcgggaca
     5641 gtatgtccgc acggcgcaga tggagcgcca actacgttca tttacatggg agttatgatg
     5701 tcgatcaagc tcgccgcctc ctcggccgtc cgcaaggcgg cgacgtgtgg cgccctcgcg
     5761 gttgccgcct tgacgctctc ggccgccccc gcactggccg acgccccgac cgtggtgaag
     5821 ggcccggacg cacgaggcga catctcgtac gcggcgtgcc ccggcggaac gcacctgatc
     5881 ggcgggggct attcctggaa tcccatctac accaacggcg gctctcccag cgacaccgta
     5941 gacatcaact ccccctctgg ggccaaggcg aacacctggg cggcaaaggc gcataagggc
     6001 gtcatcgcgg cctacgctct ctgcgccaag gactgacaag ttcggtgtcg ggccttcaca
     6061 acgtgcatgg ctccaagccc tccgtgagcg cccgtatggc gtgctcgcga ctgtttgggc
     6121 gcgcccgccg tccggcaagg gagcagtcgc ccgcggtcgc gctgcgcgct accgggcagg
     6181 gctgacccgg acccgggcag gggaggaggc gaacgtcgct gatcaggccc ggaggaacgg
     6241 accgagagcc gggtgaggtc gtcgagtcgg tcacccggct gctggacgcc gcggggggcg
     6301 tgacgggagg cgcgtggggt ggggtacgcg gccggcgcca cacggcaccg gccgggtacc
     6361 cggtgctact tgacgccgac gacgaggtac tccgggccgt ccaggtggct cacggcaatg
     6421 tcccggaagc ccgccgcgcg catccagtcg ccgcactcgg caccggtgta acccagtccg
     6481 ccggccgaga ccgtggagac gttgagactg atcagcaggc ccgtggtgcg ttcgcggcgg
     6541 tcgtcgtcga tcagggactc gtagaccagc agccggccgt cctccggcag cgcctcgtac
     6601 gccttgccga tgagggtctt cttggtgtcc aggtcccagt cgtgcaggac gtgtcccatc
     6661 acgatcgcgt cggcggtcgg cagcgggtcg gtgaagaagt cgccgccggc gaagcacgcc
     6721 cggtcggtga ggccgacccg ttcgaggtgg gcgtcgaagc cggggccgac cactggcagg
     6781 tcgaagccga tgccctggag gtgtgggttc cgggacagca cctgggccag cagtgagccc
     6841 tcggcgcagc ccacatcggc gaccgtccgc gaccgcgacc agtcgtaccg ttccgcgatg
     6901 gcctggttgg cgcccatgct gtagccggtc atcgcccgca ggaatccggt cacctggtcc
     6961 ggtgcggcgt acgcctcgcc gaaggtgtcg tccgtggcgt cggcgcccac cagcttcggg
     7021 tcgccggcgc cgccctggtc tgcggaccgc gaggcggcca gcgccgcgga gaagtccagt
     7081 cggccgccgc tgcgcagcgc gtcggtcagc cccgcccagc agccgaagcc cgcgttgagg
     7141 aaggagaggt agccggagat gtcggtggcg ggcttgcgag ggtccaggta gcggtcggcg
     7201 acgggggagt tgcggtagac gccgccgtcg cgctccagca gtcccaggga caccagggcg
     7261 tcgaggaagt cggcggcgcc gcggccggcg atctccagcc tcccggtgag ttcggcgcgg
     7321 gtggcgggac gtacggcaag ctcctcgaac acgcccagtt cgaccgcgct cagcagcgcc
     7381 ttggacttcc agaaggcgac cgcgacgtcg atgatggcat gcggtgagtc ggccgggaag
     7441 gcggcctcgg gctgcggggt ggtcatgctc ggttctccgt tcgtgcggtg tgggcgtgtg
     7501 cgggcgcttc aaggggcccc ggcatcaggt cagccggagg tcctggtaga cggcgtcacc
     7561 gatggtgatc attcgttcct ggtgctcttc ctgccaggtc ttgccgttga ggtgcagcgc
     7621 gaccaccagg ccggcgtccg ggtcggcgaa ggccgccgag gtccacagcc cgtagtggcc
     7681 gaaggtgcgc ggcgaggcgt ggcggctgaa ggccgtgcac tcgtcgccga ggtggcggga
     7741 ctcgacgcgg aagcccagcc cccagtcggc gttgccgaac gggtccacca ggccgacccg
     7801 gtggtgcgcg gtgagcgcca tgacggtctg cggcagcagg atgcgcccgt ggcgcccccg
     7861 gccgccctcc gccagcgcgg cgaagaacag cgccaggtcg gacatcggcc cgcggatgtt
     7921 caggccgggg atgggccggg tgcaggagga ctcggtggcg taccagtggg tgggctgggc
     7981 aggtaggccg ccgccggtga tgtggatgag tggcagccgg tccgcctcgg cgcggtactc
     8041 ctgcggggtg agcaccacgc gggtgtcggt catcccgcag ggcgccagga tctcctcggc
     8101 gagatagcgc tcgtagtcgc gaccgtccac ggcgcggacg acctcggcga tcaggaacca
     8161 cgcccaccac ggcccgtagt tgatccgcgc gccgggtggc gtccccgccg ggaccgtcat
     8221 gttccgcagc tgctcacggc ggagcgcgac cggggcggcc atggccccgt gcagcgggtc
     8281 caggcccatg gggacggccg aggtgtgggt gagcagttgg tagagggtga cccgttcgcg
     8341 gccgtcgccg tcgtaccagg gaaggtagcg tgcgaccggc gccgccgggt ccagcaggcc
     8401 ccgctcccac aactggccga tcgccaccgc gcccagcgtc ttggagcagc agtaccagat
     8461 gggcagggag gcgcgggtga agggcactcc ggggcggcag ctgcccaggg cggcggagac
     8521 ggtggtgccg ctcggggcgt ggctgacgtg gagctgggcg ccgggggtgg ttcggccgag
     8581 ttcggtgcgc agggcggcca tcgtacgggg cagcgcctcg gtggcggcgc ggaccgcgtc
     8641 ggcctcggcg tccggcgcgg tgaccgccgc ggcggcgccc ggccacgggc ccgccgcctg
     8701 cggcgggtcg gcggtgaacc cccgcagccg ggccagcgcc ccggacgggt cctgttgcag
     8761 cagccggtcc aggaagaaga tgaagaggaa caccccttcc aggaccagcc gtccgtgctc
     8821 gaagagccgc acccgccgct cgccgtcccc gaacagcagg acggcggcct cctcgtgccg
     8881 gagggtcagg acgagggtgg gccgttcgtc ccactcgccg gcgcggaacc acagggcgcc
     8941 ggtggccaga tccgtcagga cgagaatctg cccggccacc ccgacaggcg gatcggtcag
     9001 gcgcaggccg agccggaggg cctcgcctgc ttcgggccgc tgcccggccg cggcctcggc
     9061 gtgccgcagc cactcccggg agaacagcgg gtgggcggcg ggtgccgccg taccggaccc
     9121 gtgcggcgct gtgcaggcgg cgctcaccga gcgacctcgg cgacggtgaa gcggacgatg
     9181 ttccggctgg tcaggcttcc gtcgggggcg cgcagttcgg ccagctcggc gtcgaccgcc
     9241 ttgaccgcgt cggtcatcgc gtcctcgggc acgctctccc agaactgccg gcccgcggtg
     9301 gaccacaccc actgccacca ctggtggggg ccgcggaagc gggtgacaca ggtccgctcc
     9361 acggtgtcga cggagctgaa gccctcctcg gacagcatgg cgtgcaggtc ctcgacggag
     9421 cggaacgggc tgtccggcgg gagccggtgg gaggaggcac cgccgtaggg ggcactggcg
     9481 gcgaagaccg ggttccagcg ctcgtcctgg cggccccacc aggagatggc gaaccggcca
     9541 ccgtcggcaa ggagtcggcg gtagcgggcg gccgcggccc tggggtgggg gaagaagaac
     9601 atcgagatcc cggcgagtac cgcgtcgaag gtaccgtcga cgggcggtcc gggctgccag
     9661 tgggcggtct cggcgtcggc gacgagggcg cgggcgttgc ccagcccttc gtccgcgatg
     9721 gccgcgcggg accgctccac catgcccgcg gacaggtcga ttccggtcac cgagccgctc
     9781 ggcccgacgg cccgcgccgc gggaacgagc acggcgccgg tgccacaccc cacgtccagg
     9841 acccgctcgc cctcccggac gcgggcctcc tccaccaact ggcggccgag ggcgccgaag
     9901 tgcgagacac ctaccttttc gtacgtcggg gcgctgcggt cgaagagccg ggccagggcc
     9961 tgcttgtgct cgtccggcgc cgggtgccga agggtcccgc tcatggggtc ctccccttgt
    10021 cctgtgtgag gttgccgctc tcgtcgagcc gtacggtgcg cccggtgcgg gcggaggtgt
    10081 acacggcgtg caccaccgcc accgcccgcc gtcccgcggc gccgtcgacc aggggtggcc
    10141 ggccggtgcg gaccgcgtcg cagaagtcgg cgagctggtc gcggtggggc tggtggagca
    10201 ggccgatgcg gtcgcgcggc gggggctccc gcggcggcgg gcaccggtcg gcggcctggt
    10261 tgccgtcgcc atacgcgcca taggcggtgg gccgctcgcc ctcgcgggcg gtgtggaagt
    10321 aggccagctc gtcgttgtcg atgacgaccg agccgcgctc gccgttgacc gcgacccggg
    10381 tgggacgccc cgggtaggcg gcggtggtgg ccagcagcgc gccgagcgcg ccgtcggcga
    10441 acttcaggct ggcggtggcc acgtcctcga cctcgatgcc gtcgtgggcg agcaggccgg
    10501 tgtgggcggc ggcctccacc acggggccgg ccagccactg ggcgaggtcg acggcgtgca
    10561 cggcctggtt catcagggcg ccgccgccgt ccagggcgcg ggtgccgcgc cactgccccg
    10621 acgcgtagta ggaccgcgcc cgccacaggg ggacctcgat gaggaccgag gtgatccggc
    10681 ccagggtgcc gtcctcgatg gcggccctgg ccacttcggc ggcggggtcg aagcggtgct
    10741 gggagatgac gccgagggtg cggccggtgt gccgggcggc ggcgatcagc cggtcggcgg
    10801 cctccggtgt gacgtcgacg ggcttttcga ccaggacgtg cttgcccgcg cgcagggctg
    10861 cggtgcccag ttcggcgtgg gtgccggagg gagtgcacac ggcgacggcg tcgatgtccg
    10921 tgcgggccag cagctcgggc acggcgagtg cctcgcagcc cagttcggcg gcgagccggt
    10981 gtgcccgtac ggggtcccgt ccggcgaccg ccaccagacg ggcccgctca cgcagcgggc
    11041 cgtcgggccg ggccagcaag cggccgagga agccaccgat cgagccgcag ccgaggatgc
    11101 cgaagcgcag cacggccgcc tcctcagccc gccaccgggg caatggtgtt gcccaggtag
    11161 ttggggagtt cggtgagcag ctgctgctgg tggtccaggt cggtggggta ggcggcgcgg
    11221 tagcggcggg tgacctcctg gacctcgcgc caggtggcgg gcagcacccc gccgttgtac
    11281 tggggggcga gctggtcgta gagggtggtg ccgggccgca ggtagagctg gttgatgccg
    11341 aaccaggcgg gcagcttcgc ggcccagtcg accaggcggc cggagatgca cgcctggtcc
    11401 tgcggcagcc ccagcaggac gaaggcgaag ggggtgatgc cggcgtcccg cagcttgagg
    11461 acggcctcct cgatctgtgc ctcgctgacc cgcttgtgga cgccggtgtc ggcgatggcg
    11521 ggcgattcgg cgcccagcca catgccctgg cagccggccc gcgcccaggc ggtgacgtcg
    11581 ttcttcagga cgacctcggc gcgggtctgg ccgacccagc ccaccccgcg gccctccagc
    11641 cgggcgcaca gctcgctgta gaaggcgcgg ttgatgccga agacgtagtc gaggaagaac
    11701 acgaactcca ggcccgcggc ctgctgggcc tcgatctcgc gcaccacccg gtccagcggc
    11761 tggttgcgca tcttggtgcc gaacggcaga tggcagaagg tgcagccgta ggtgcagccg
    11821 cgggcggcga gcaccatgcc gcaggggccg ggcagcggca gcccaccgga gatgacctcg
    11881 gccgtgtagt cggcggtggg caccaggtcg taggcgggga aggcgagttc ctccaggggg
    11941 aggttgggga agggacgggg gcggggctcg ggtgagtcca gcaggttgtg gggggtggtg
    12001 gcgcccggga gcacgggtgc gtcggcgccg gccagcaggg cgcggaccgc gccgacggtg
    12061 gccgaatcgg tctcgccgca ggcgatgtgg tccacgccca gctcgtcgcg ggtggaggcg
    12121 ggcaggtggg tgccgtgcgg gccgaccgcg acggtgcggg ccgtggggta gcgggacgcg
    12181 gcgcgctcga cggcggcccg tacggagtcc agctccagcg ggtagcactg ggcacggtcg
    12241 gcgatcgcgg agaagacgac cagcaggtcg aactcctcgc cgtcgggcgc ctcctggagc
    12301 cgctggtccc acacggtgac ggtgtggccc tccgccctca ggtggccggc ggcggtgacg
    12361 gcgtccaggg ggagctggat gaagtactgg tcgaacttgt tgctggggat gacgaggcag
    12421 atccggctca tgggcggttc actctcacag tcgggtcggc agggcggcgg gggtcagggg
    12481 gccggagggc gcggggtgtt cggcgcgggc cagttcggcc agccggccga tgcggtcgag
    12541 gggccgcagg tccagtgcgg ggcgcgggcc ggggccgagc agggccgcga tgccgtgccg
    12601 cagcgcgttg tccatcgggg agtcggggat cagccactcg cggtggccgt gcggcccgtc
    12661 catggtcagc cggtgggtgt tgcggggcag ccgggtgccg ttgggcagga agaccgggtc
    12721 gagttccagg gtgaggagga ccggtccggc ctcgatccgg gccagccgca gccggctgtc
    12781 ggcggcgggt gcggtgcgcc gggcccagga gggcgcgggg gccgcgtgcg gggcgtcggg
    12841 gccgacgatg gtggagtaca gctcgacctc gacctcgccc gcggggccgg cacccgcgct
    12901 cagtgtcgtg gtgtcgtggg ccgcggtgct gaccaggtgg gggtcacggg cgatccgtac
    12961 ggcctgtggc tcgggcccgg ccagcagata gtggtggaag gcccgggtgg gcaggaagcc
    13021 gccgaggacg gcgagcatgt gcagccactc gtagccgaag acgccgtagt cgaggtcgac
    13081 gaagcggccg gccgcgatgt cctcgcggcg gtccttgcag aaggcgatgc ggatggccgc
    13141 caccgggtgc cggggggcga actcggcgcg tacggcctca agcatggcgg gagccttggc
    13201 gtgcgcgtac tggttcatca ccaccaggcg ggcccggtcg tacgcgccga gcagcgcggt
    13261 gagttcgggg ccctcccagg accggcaggc cggcttctcc agcaggatgc gggcctcggg
    13321 gtcgcgggcg aggacggcgg ccacggcctg tacgtggccg gcggtcgggg tgcagaccga
    13381 ccagacgtcc accggccggt ccgtggacag ttcccccacg gtggcggcgg tggggaaggg
    13441 ggcgccgcag ccgggcgcgg tggggtccac gacggacacg gacatgccca tgccgtcgag
    13501 cagttggtgg tgcagtcggc cggccacgcc gtggccgacg acgcacacat gcggcctacc
    13561 gggcatgggc gtcctcaccg gaggtctcag cggtgccgga gaacgctccc gtgcccagcg
    13621 gggcggaccg cgcgcacagg tactgggtgt agtacgcgtc gaacagcccg gcgtcgtcga
    13681 tgatcgagtc caccggctcc aggtggaggc cgggcgggaa ccgctccgga tcgcggcaga
    13741 gggcgagcgc ggcgagcagg gtgccggcgc ggtaggcgtc gtagccgcgg ttggcgatgc
    13801 cctcgtactc gaagaggttc agcgagcggc cgtcgcccag cacagtggcg gtggtggcgt
    13861 gcggcaggtc gtagcgcacg ccgacgtgcg ggatgcgctg cgcggtggca ccggggtagc
    13921 cgtcggtcag cacgctgaag tcctttgtgg cgaagccggc caacagcacg ccgtcgggca
    13981 gcagcggcac gtcctcggcg gtgacggcgg tgccgccgct gctgccgagg atgaggaacg
    14041 gccgctgccg gtcgagggcc tcggcgatgc tgcggtgggt ctcgaagccg tcctcggcgg
    14101 cggtgatcag cgccaggatg tcggtgtcca ccacggcgac ccggcagccc agcgcccgca
    14161 gcgagcgggc cgcccgtgcg cccagggtgc cgtagcccag cagcaggacg tgccggccga
    14221 tgaatttctg gccgggcacg atcgctcgca gccggcgcac gcaggagtcg gcgatctcgt
    14281 tgtagcccag ccgtgacttc agctgggagc gggccatgtt cagcacgggg atggccagtt
    14341 cgccgggggc ggccgtgatg cgcttgagcc cgctgaccgt cagctcgatg gcggcgtcca
    14401 cccgtgctcc cggcctgtcg gcgccgtagc cctgggcgag caggccgccg tcgtcgatga
    14461 ccaggacctt gcggccggcg acgtgcgccc ggcggacgaa gtcggccacc tgggcgtcca
    14521 ccgcccgtgc gcgggccgtt tccgccgctc cggccgtgcc gttgatgacg gagttgtcca
    14581 gggtgtcgct ggcgtagccg cggcgcagga accaggagtg cacccgctcg cggtgctgcg
    14641 tccggtcgcc cttggacagc gcgaagatcc actcggggtc gagtccggcg cgctccatgg
    14701 ccagcaggaa gccgacgctg ttctccacgt agtggtcccg gaagatcaac gcccatccgg
    14761 cgagcgcggg ttcgggctgg gcatatcggc ccgtcagcgg catgccggcc gcgatggcgg
    14821 cggcctcggc ctcggtgtag caccgggccc gccggccgat cgcctcggtc agcgcggtga
    14881 acaggtcacg ggcccgctcc gagggggtgt cggaggcggt gagcacgatg cggcggaccc
    14941 ccggcccgtc gaggacgggg tccagggtgc cgggcggctg gtcggacagc ggccggctgc
    15001 ggatgtccag ccggtcgccg cccacccgca ccgtgtactg gccgggcccg tgcacggtca
    15061 gctccggtcg cgccggcgcc ccgccgtggc cgtcgaggac cgcgcgcacg gccgccagca
    15121 ggtcaccgat gccgagcggc ccctccaaca cttcgcacgg gcccggcgga tggggatccc
    15181 ccagtcccct gtcggggacg gtgcgacgcg aagcaacatc agataccgac atatatccac
    15241 ccacgccagg cgtgtattcc tcgtgagaac ggacgtgttg cggccgggcc ggagtcagga
    15301 ggtgctcctg gtccggctgg tgttctcagg tcagcctgcc gtgcggggga tcttgacgac
    15361 catcgtggag atccacgatc ccggcggtcg cccggcccgg gcgacggccc tggtcagccg
    15421 gatgcggtga ggctccgcgc gctggaggag gccgccgtgc ccgtcccggt cagccgggag
    15481 gcgagctggg tgcggcgggt cacgccgagt ttgcggtagg cgttggtgag gtgggtctcc
    15541 acggtgcggc gggccaggtg gagtacctcg ccgatctggg cgttcgtctg gccctgggcc
    15601 gccagctcga cgatgcgccg ctctgcccgg gtgagtgcgg cgctgcccgt cgcgtgccgg
    15661 cgggtcccgc gggcgccgct ggcccgcagg gcgttaccgg tggcgcggag caggcgtccg
    15721 gtggcgggcg cgtcggggtg ttcggtgggg tcgggggcca gcaggcgcag tgccagggcg
    15781 tgggcctcgt gcaggtcctc gcggcccttg cggctgttcc cggcgtggat ccgcgcgtgg
    15841 cccaggtcga ggagggtctc gacgagttcg acgggggccg gtgcggtcct cagcacggtc
    15901 gcggcctcgc ccagcgactc aagcccccgg cggccgccca cggccgcggc gtgggcccgc
    15961 agggcccggc taaccgtgcg gggtgtcccc caggtccgcg cgtggcgcag ttcctcctcg
    16021 gcgaggtcca gggctctcgc cggctgaccg agtccgacca gggcgagggc ggcaccggag
    16081 cgccaggggg tggccacggg gctgacgaag tcgcgggcgc tctgaccgcg gccgcaggac
    16141 aggtagtcgt cgagggcggc ctgccagttg ccctcggcca tgtgcagaga ggctctggcg
    16201 tagtgcagtt cgttccattc ccaggagctg tcggcgctct cctcgtcgag gccggccagc
    16261 agccgccggg cgtgggcacg gtggccgagt tcgcagtggg cgagtgccac catggacgcc
    16321 aggtggggca tgcggatacc ctgcccggcg cacgcgtcga ggagcggggc gttctcggcg
    16381 atcacgcgcc ggaagtcacc tgtccacagg gccgcttcgg cccgcacgct gatcaggcac
    16441 tgccggccga tgtccgtcag atccgggagc gcgggcgggg cggggagggc ctcttcggcg
    16501 agggcgcgtg cctcgtccag ccggtcggcc cactgcagca aggtggccgc ggttcccagc
    16561 cagccgtcgc ggagccgggg gtccaccggc gcggccagcc gcggcagcac acggccgagg
    16621 gcctcggccg ccgacagccg gccggtcccg acctcgtact cggtgaccag gccgcaggcg
    16681 agcggctcga cggcggcggg ggccgtcgcc gccagttccc gcatgcgggc gacggcgttg
    16741 cgccatgcga ccgcgtcgtg ggaggccatg acggcggcgg tggtctgcag cacacggaca
    16801 agctcgccgt cgtccacggc gctgcccact tggctcatga cgcgcatggc ggtggccgtg
    16861 cggccccggg cgacgagcgc agcgccgagg gcgggtgcga cggctgcgcg ttcatgacgg
    16921 tcggcgtgca gctccagcgc cgctcgcagc ctgcggatac cggcatccgc gctgcccggc
    16981 agctccaggg cgccgaggcg cagggtgagc ccggcgcggc ggccgggggt gagcggagcg
    17041 gtgagggcgt ggcggaggaa agcggtggcc tcgtcgaccc ggccgccgcg tacggcgtcc
    17101 tcggccgcgt cctccagcga ctgcgtcatc cactcctcgc cgggccggtc gaggtggaga
    17161 agctgggcgg cgacgtccgc cgtgggcgcg ccgcgctcgt cgagcaggcg cgcgatacgg
    17221 ccgcgcagcg cgcacagttc ggccggatcg accgccgcga gggcggcctc gcgtgccagc
    17281 gggtgcgaga agaggcggcg gagggccgac gcgcccgcgg acgcggcgcg atggtccggg
    17341 cggaggccgg cggcctcgtg gagcagggct cctccgagca gcgccgcgcc gtccccggcc
    17401 acggcgagcg ccagggcgag gcggcgcgac cacggggtcg cccgggcccg tatccaatgg
    17461 acgatcgcgt cacggtagcg gcttccgccc agctcggaca ggctgcctgg cagcggcccc
    17521 tcacggaggt cggcgaggag agcgtgcacc agcaccggat tgccggcgca cgcccggatg
    17581 cataactcgg cccggtcgga gccgtgtccg cgggcggaca ccagacgggc cacggcctcc
    17641 gggcccagcg ggcggagcac cacggacgtg cccgtcgcac tgggcagcac ggcggtgccc
    17701 ttctcccggc actcggtcag gaccagcagc acgggcaggt ccgccagccg acgggccaga
    17761 tagccgagcc aacggcgtga cgccatgtcg gcatcgtgca ggtcgtcgac ggccagaagc
    17821 acgggccgac ggtcggcggt ccgcgccaag cgggtcacaa ggcggtggaa gaccatctgc
    17881 tcctcggccg ccggtaggtc tgcgaagggc acctccccgt cctcgggaaa gagctggcgc
    17941 acgagagcga aggggaaccc cgactcctcc ggcgaacagt ccgcgcgcag cacacgcatc
    18001 gccccgcccg ccgcctcccg ccccgccgcc tcccgcaaca gggcggtgcg gcccgtcccc
    18061 gccgccgcac cgaacaccag ccaacggccc acaccggacc gcgcggactc tccggccctc
    18121 gccgcggccg ccagcgcttc ctcgcgttcg agaagcacac tgcccatacc cacactcctc
    18181 cgcctcggtg cacacgacgc ccctgcggtg cagggcgccc gagatgaata ctgcatgccg
    18241 aaagtagcga aatcccctat tccgggccag tattcgtctc cgggcgccat ctcgcatgac
    18301 ctggccagac atgtaatgat cttgatgcgg agtacgcctt gtcgccgagc aggcggtcgg
    18361 gccgtgtgcg gggccgtccg ccctccggcc gggcaacgcg gacgcgcccg agggccgccg
    18421 ggccgagcgc cgcgcccctc gatgcgggct cggtcctcct tggacgcggc ccacggaggc
    18481 atctggggcc tgacgttcga tgcgatgccg tgcggcggca tcacgcacag cagccccacc
    18541 ccgagtgccg ggcgagaaaa taccctgcgg aaacctcggt tttcactcaa ggaactcaag
    18601 agaggaacag cgggctcagc tgacgcagtt ggcgcggaag gtggtgcgcg ccggggcggc
    18661 gggtgtgatc gtgcgggtga acgatggtgg ctctgttctc gtgcagtcgc tgccagaccc
    18721 cggcgttgtt cggctcgatt ctcgaccaca actcgtcgtc aactagccag ggttgaggat
    18781 tgcgtttgct cacacgaaac caaccgccgc acccattcag aattaacggc taccggagtt
    18841 gcgttagaga ctcttagacc cacgcaacag gtcgggtgcc ccgcgcactg cgcggggcac
    18901 ccgacccctt cgtcgccggg cggctcagcc gaaggcgagc ctgccgatgg agtaccagct
    18961 cgtctcgtgg ttgacgctac cgaccgctgt gatcttgatg gtgtcgccct ccttgacgag
    19021 gatggtggag cattggcgcg cctcgacttc gaagcggctc atgacgccgg tcgttccgac
    19081 ttcgaggacg accgtgccct ggtagttccc attccccttg ttgttgcact gaaggaagcc
    19141 gtaggtgggc gcggttgtct ggtacccggc cgtcgcggtg atggtgttct tccgttgcca
    19201 gggcaggctg cccggctcgg acaccaccgc cgcggtcacc ttgtcggcgt tgaggttgcc
    19261 gtggaccctt ccgcgcacgg tcaggttgcg gatttccagg tccggttggt tgacggtgac
    19321 gtaggtgttg aggacgcgtt cggcgtagtc ggtgccctgc tggacgcgac tgcggaggta
    19381 gaacatggtg ttgcgggaga ggttcttgac ttcgaacttg gtgtagtcgg tgacgtcgat
    19441 ctcggcgttc tcgtagagca gtgtctgtgt ggcgccggag gaacggtccc aggtgagggt
    19501 gaccgagtcg ccgttctcga tgatgagcgg gtcggccttg aagttgtcga ggtagaagcc
    19561 cggggggaat tttccgacgg ccttgacggc ctcgtcggtc cgccagcccg aggattcgtt
    19621 ggcgcgccat ttggtgccga tgatgacggc gccggttccc accttgcggc tgatgcggag
    19681 cttgttgacc tggagggtga tgccgcgttc gttgtcgatg acggcgtggc cggaggtggg
    19741 cttgaaggtg atgcggttgc cgctgacggt gtgggtccag ccgaggttgt tgctggcctg
    19801 gattccgccg aggtcgagtg cgaggtgcca ggcctcgttg ccgtggtcga tgtcgacgtc
    19861 gatctggctg acctggatct cgccgggaat gctgcggctg ccgacgagga tgatgtcggc
    19921 gagctcgacg gagccgctgg cggggctgac ggtgacgggg tcggggacgg tgtcgatgct
    19981 ccagtcgatt tcgccggtga agtcggaggc cgtgccgttg ccgacgcgtt gctgggtgac
    20041 gatggccatg ctcgtggtgg tccttcctgg tgtgggcgcg gtggttcagc gggttgcttc
    20101 ggcggcgtcg ttgaggacga ggtagccgct gcggagttcg ggatcaccca ggggcagttc
    20161 gcccgggtcc ggggcggtga tgggcaggtg ctgccaggtg ccttgggtgt cggtgggttc
    20221 ggcccaggcc caggtgccgg atgccgtcgc agggtggggc agtacggccg ttcgcgggtc
    20281 ggcggtggtg ccggccatca gcgggccggt gcggaagcac acggccatgc gggccagggc
    20341 ggtgtccgtg aacgccgggg ggatgtggac ggcggaggcc gggaggacgt cggtggtggc
    20401 gtggacggcg gcacgggggt ctgcgagcag ggtgacggtg gcggtgctgg ttccggcgaa
    20461 ggcgagttgg aggcgttcgc cgttgtcgat cgggcgcagg tagccgctgg atccgtcggc
    20521 gggtggggtg atggtgtcga agtgggcgta gtcgtcgttg aggacgtatc cgacgaggcc
    20581 gtcgtcggtg gcgcgtggct ggccgagtcg gacgatccac ttccagtcgg gcatggccgg
    20641 tgcgtgatcg tcggggtcga ggacctcgtt ccaaccgacc gaggtgcggg gcgggccgca
    20701 cagttcgagg tcgaggcggg cgcggagcag ggcgaggggc cggccgagca ggaacccgag
    20761 actggcgtcg tcggggctgt cggggtcgat ggtggtcaag gcgtcgtcga gggtggcgcg
    20821 cagggcgtcg aaggtggccg gtccgcgctc ggcgagcgca tggaggaagt ggtgggcgtg
    20881 cggggcgacg tcttcgagtt cggcgagcgt ggccacggag gagccgggca gtggtagcca
    20941 gacgacggac ttggtgccgt cgggcttgag gacggtgcgt agttcaccca gggcctggcc
    21001 gtcggggtcg tagcaggcca gggtgcggtc gagccggttg tggagcagcc aggcacagac
    21061 cgggttggcg ccgggggtga ggtcgatggg ttggtcggtg gtggcgtgga ggaagtcgaa
    21121 ggccagccgg gcgggctgga agaggcgggg ggacagttcg aggaaccggt cggggtcgtc
    21181 ggtctcgacg gtgtggtccg gcaccatggc gtcgggccgt acgtagggcc aacggcggtt
    21241 gtcgccgatc aggttgaggg tgcggccgaa gcggtcgacc agggacagct ggcggaatgc
    21301 gaactgaccg gtgcggactt cgtggaaggg ttcggactcc ggtggccggc tcgggtggga
    21361 ggggacggtg ccgggcacgg ggaagtggcg gtcgccgtgt ccgatgaggt cgcccatggc
    21421 ttccaggggg cgggcggtgg aacgcgggtc gcgttggtcg aggtgggcgg tcaggccctc
    21481 caaccgctgg gagagcatgt cgaggtcgct gagctgtgtg cggaggttcc gaaggtcggg
    21541 gaggtcctgg cggccggcgg cgtaggcgtc gagttcgcct tcgaggatgg ggccggcgga
    21601 cggggtgagc gggatgcggc cggtgaggac gaaggactcg gggacggttc cggtgccttg
    21661 ccagcggtag cggttgccgt cgaacgtcca gtggcgggtg ccgtcgtgtt cgctgtaggg
    21721 cagcggccag cattcgatgt cccagacgag gaacagcggt tgccatggct gccgccaggc
    21781 ggccgtgccg tattcgggca gtgtgccggt gacgtcgtcg agtccggttc cggtgtggcg
    21841 ggcgcgggcc aggatgaaga actcggtcag caggtcggtg aacggcgcgg gaaggttggc
    21901 ggtgttgacc tggtccacgt cggagcgcac ggcggcggcg tcgatcgggc ccacggcggt
    21961 gaccaggcgg tcctcggtgc ggcagggcag cggggtgtca cggctgagcg gggcgtggac
    22021 gtgcccgccc tggagcagga ccaccgggtc ggcgacgtga aggaacgggg acttgggtac
    22081 ccgttgcagg acgcggttcg gcgggaggcc cttgccgcgg gcgtactccg ccgcgctcgc
    22141 ctccagctcc tcgggagtgt cgccccacgg cagggcgttg cgtttcgcgc acaagtcggc
    22201 ggcgagcgcg gcgacctttc cggccgcgcc agcctggttc gccgggtcga gttcgtcgtc
    22261 gacgcggttc tggaagtccc ggggctggcg gtcggcgttc gacagcgccc agagcacgta
    22321 gagccggtcc tgggctgctg ccaggtcgcg ttcgacgccg tcgtgctcgg cctgggcgcg
    22381 attgagcgcc gcgacgatgt cggcctcggc ggtgcgtgtg cgggcgcgtt ccctggcacc
    22441 gagtcggacc gggcccgttt cccggtcctc gccgcgttcg acgatgcgcc aggtgaagcc
    22501 gccgggtacg gggccgaatc cgctctggtg ggcggccgcg tcggtcaggt cgtcgccgtc
    22561 ggcgcggtcc agcgcgtcga gggtgcccag ggcgaacgcc cgcacgaggc gggagtcgtc
    22621 gtcggacagg gccccggggc cggccgcggc gtcggtcagt gcggtggccg cctcggcggt
    22681 gttgttcccg accgagaccg cgatgctgtt gacggcaggg atgtccgatg cggggagggg
    22741 accggccggc tgccagtcca cgcccagcgc gctgccggtg tagagcgagc ggcgggtgtt
    22801 gctgccggcc atcggggcga gccattcgag gtcgtccagc agttcccgga ggtcttcggc
    22861 gtcgtcgagg acgtcgctgt cgggggtgga gtagaagccg gcgacgtagt agtccagccg
    22921 ctcgtctccc gctacgtcgt ccaggccgtc gtggagggag aagacgttgg tgttgtaggg
    22981 ctggaaggcg gagaaggtca gcaggccggg cccgagcgcc gtcaggaacg gcgtcggcgc
    23041 gtcgccgggt tcgcgccagg gactggaggt ggtcagttcg tggcagcggc ccattttggt
    23101 ggcggtggtc cgctcggcgc gcgggtcgag cgcggagacg gtgccggagt ccaaaccgag
    23161 gtggtcgctc tcgatcagcc aggcgcggac gttccgcgag gcggcgcggt agcgcacgac
    23221 cagccagcgg ttgggcacca gggggaagtc gtcctcgtcg gtctcggtgt cgtgccggcc
    23281 gcgggtcagg gcttcgggca gctgccactg gaggtagaca ccgcggttct cggggcgggc
    23341 gggccagtcc gcatcgatgg agaacggcga gggctcggcg ggggccgcgg tgtcctgggt
    23401 gtggaagaag ttggcgatcc agcggtgcca gacgaacgcc ccgtcggggt tctgcatccg
    23461 ggcgttcacc gccagtgcgg cgacctcgac cggcacgacc agatggttgt tgctgctgcg
    23521 cgcgggcatc acgcgctcct ttcgaaacgg gggggggggc ggctcggtca ggggcgagtg
    23581 aaggtctgca cctgcggcgc cttgatcatc tgcagggtga gctgcgccga ggacagggcg
    23641 ggcacgccgt gcgcgcgggc gagcgccggc aggaggggat caccgggacc ggcgacgttc
    23701 aggacgtcgt acccgtcgcc acgcaggaac cgcccgaaac ggtcgtcgcc gggattctcg
    23761 gggaactcgc ccatcggata accgatgtcc gggccgctga gcttgcgcag ctcgatggtg
    23821 ccgatgtcgc tgaagccgaa gtgcagcccc tgcggcggct cggccagggt gaaagtgtcg
    23881 atcacttccg agaacagcag cagcaggacg tcgctgccgt aggaggcccg gtgaatctcc
    23941 tcgacgggcc ggtcgccacg gaaacccgtc atgacggtct tcggccagtt ccagacgagg
    24001 tcggaccgca gcagcagccc gcacggcgcg ggccgcggca cccgccgtgc cagcgcgttg
    24061 aggtcggcat ccacggcgtg ccccacgccg acgctcaacg caccgtcgac agccgcccgc
    24121 acccacgcgg catcgacgtg gaagaaccgc agcgactccg ggggaagcat tcgcgggtcg
    24181 ggcaccagat gctcgaacgg catcatctcc agcagcggga gccgggccag ccacgcactg
    24241 accggctcca actcgcgtgc cgtggcctgc cgcaggacat ccgccacctg cgcctcggcc
    24301 agcgccgacc ggactcccgc agcggtcagc gcggcgccgg atcccgtacg acggtgccgg
    24361 gcctggccac ggacccgccc ggcggtgagg tcggcacccg cgccggcaag cgccgacgcc
    24421 aaccgcgcgg tgccggaaga tccgtcgagc agccggtcga aggcgtcccg ggccggatgc
    24481 tcccggagca acagccccgc tgtggcggga gagacggcgc ggccgaccaa ctcggggtgg
    24541 gtgagcaggc ggcggaccgc gccacgtgcc gccttgcgga aggccagcag ggccgtgcgg
    24601 aactccgcgt cggccagggc gagcgtgcga ccgaggctga aggccgcggc gtaggaggca
    24661 tcgaagaccc cgtacggctg gacgtacgcc agcgcctcac ccgccgactc cagacgttcg
    24721 ccactcgacg gtgcgggcac cggctgggcg ggagcggccg tcagcgggcc ccggtagaag
    24781 ccgaagccgc gctcaccggt ctccaggcgc tgcggcagcg cggtggcacc gatgctgagc
    24841 cgctccagcg ccgctcgctg cgcggcggac gggttctgcg gcggagcggg gaccggcagg
    24901 cgcaacaaca gatcgggctg cgcggccagt tgctgtgcca ggtcgccgaa gcccatgccg
    24961 gtgtccggct cggtctcgaa ggcccaggac cacagggaaa ccatgcggag cccctggggc
    25021 ggggcggccg tgccaccgag gtgaccctcg aatccgtcga acgagagcag gtggacgacg
    25081 tgccgaccgc cggccgcgtc ggggaagcgg ttggcgacga cgaccgcctt gagctcgtcc
    25141 tcgtccgggg c
//
