LOCUS       NZ_CP104098            20708 bp    DNA     linear   CON 08-NOV-2024
DEFINITION  Streptomyces noursei strain IFO14147 chromosome, complete genome.
ACCESSION   NZ_CP104098
VERSION     NZ_CP104098.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces noursei
  ORGANISM  Streptomyces noursei
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9223378)
  AUTHORS   Zeng,X.
  TITLE     Transcriptome and Metabolome Analysis Revealing the Improved
            epsilon-Poly-l-Lysine Production Induced by a Microbial Call from
            Botrytis cinerea
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9223378)
  AUTHORS   Zeng,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2022) College of life science, Huaibei Normal
            University, Dongshan road 100#, Huaibei, Anhui 235000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: PGCGAP v. 1.0.34
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025163575.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 12:09:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,195
            CDSs (total)                      :: 8,101
            Genes (coding)                    :: 7,883
            CDSs (with protein)               :: 7,883
            Genes (RNA)                       :: 94
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 218
            CDSs (without protein)            :: 218
            Pseudo Genes (ambiguous residues) :: 0 of 218
            Pseudo Genes (frameshifted)       :: 93 of 218
            Pseudo Genes (incomplete)         :: 149 of 218
            Pseudo Genes (internal stop)      :: 11 of 218
            Pseudo Genes (multiple problems)  :: 33 of 218
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:04:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8109193
            Orig. end                         :: 8129901
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP104098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20708
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="28"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20708
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20708
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10708](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10708)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     misc_feature    complement(412..425)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.72"
                     /tool="antismash"
     gene            complement(419..757)
                     /locus_tag="N1H47_RS35875"
                     /old_locus_tag="N1H47_35870"
     CDS             complement(419..757)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009309525.1"
                     /locus_tag="N1H47_RS35875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35870"
                     /product="hypothetical protein"
                     /protein_id="WP_020930311.1"
                     /transl_table=11
                     /translation="MPELRIHAGRHYAVQFHYALPNDAWCVELSEAVPAPAAWAEVPNA
                     QTHLPGAAFMVAVIPDEDPSLEPTVHIHSHDEHVIPYEIMRWLMEQVAEQVEHCRLAFE
                     QGAPEAVE"
     gene            1402..1803
                     /locus_tag="N1H47_RS35880"
                     /old_locus_tag="N1H47_35875"
     CDS             1402..1803
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N1H47_RS35880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="N1H47_35875"
                     /product="hypothetical protein"
                     /protein_id="WP_124428240.1"
                     /transl_table=11
                     /translation="MENKQRSTRRKAALVAGVVLAATVAGTVPSWAEGSWSSYMSNWTN
                     GAESRRWQDNHSDGNATTIGFSGCNFGGAGAVNITLYRAVDYWPDDAQGMKFMDCGTTS
                     WGAMSIAGSYYFAYGGNHTINVNNVVVKY"
     gene            1885..2628
                     /locus_tag="N1H47_RS35885"
                     /old_locus_tag="N1H47_35880"
     CDS             1885..2628
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572533.1"
                     /locus_tag="N1H47_RS35885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35880"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_016572533.1"
                     /transl_table=11
                     /translation="MPISISDCSFMYRRGLPVLEGLSLSLGYGATVLLGPNGAGKSTLL
                     GLAASALRPASGHVRIGALDTRNRKDVKEYRRKVGWLPQQVKAIPGLRVREQVAHAGWL
                     KGMSRIQAWEASAGALEAVGLTDLSARRSSELSGGQKRRLGIAQALVHSAEVVLMDEPT
                     AGLDPRQRATFRDLVARLSSTVAVVVSTHQTEDLADIYQSVVVLDQGRVRHQGAVSSFL
                     DLAPAGSPRERQAEAAYASICTVEA"
     gene            2625..3869
                     /locus_tag="N1H47_RS35890"
                     /old_locus_tag="N1H47_35885"
     CDS             2625..3869
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N1H47_RS35890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="N1H47_35885"
                     /product="hypothetical protein"
                     /protein_id="WP_124428241.1"
                     /transl_table=11
                     /translation="MSMYLRTLLRTSTAPRAAFVLVPWLLAYSGNISNWITTGYWASVT
                     AQSSFLLGFIAPACAACAAWEGARIKRSAMLGGAPSRSRLAIAFSVLWPVMLLGVLSVV
                     LGVAVSASQASGLPRWSSFVMLTVEACVVVAHTTAGYVAGLTLPRLLAAPAALVASFVW
                     MAYPAAMNNPPWLRQLNGHNFNECCALDQVPDVRGFAAAAVVAVGVASACALWINLHGV
                     LRLLAPVSVGLALVVGCVVATPMGYQAARPRDLAELDCRTGPSGICLWPEQHGAAKEIE
                     EWGLQARRSLEAAGVRPARKVKVMTVAPRPGDVVTVMAFSAVPQDIPSCARTGQWPGSQ
                     ATGPVMAWLALTAGAQPQDLEGHYIEGDVHLARKVRRLPLAGQQRWFHRNVATLTGCDK
                     APDLAPEHFVAGAAL"
     misc_feature    4638..4652
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            4868..5164
                     /locus_tag="N1H47_RS35895"
                     /old_locus_tag="N1H47_35890"
     CDS             4868..5164
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540305.1"
                     /locus_tag="N1H47_RS35895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35890"
                     /product="hypothetical protein"
                     /protein_id="WP_037634729.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGYFKVETDGLGRLLKDLHDSQDNMRKALGALKDTGPKSMGAEA
                     LDNACDEFHDSWDNAIKKIADGTQAIEEKLKQVKQNYESLEHALRDAFAKNAK"
     gene            5225..6676
                     /locus_tag="N1H47_RS35900"
                     /old_locus_tag="N1H47_35895"
     CDS             5225..6676
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088841.1"
                     /locus_tag="N1H47_RS35900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35895"
                     /product="putative T7SS-secreted protein"
                     /protein_id="WP_016572538.1"
                     /transl_table=11
                     /translation="MTTRDFPALGFNPAPGELSSVDDVTGKLDAAKRSLDSAHAVLSRI
                     GKGDGEWQGDAANAFAKNVGDLPKYVSDSRDAMRDAVTQLRSWHTALSSYQSKGIQYES
                     EAAAAKQTVATRKTEREHAVQAYNEAAAHPDLRLAGTYYADQTALDAAQKRIDAASDRL
                     DKADRALDAARSRLDSATEELESIVKKAEELLGHHQDEARGIADRIRRATENAPDPGFW
                     ESLGDFFTRMGHSIQEWCAKHADLLKEIGDWLSIASSILGVASLLTMWCPPLSGALALA
                     SAGASLGALATHGAAKLGGADVGVMDLVGDGIGVVPFGKLGAVAMKGAKVPMKLVQVEG
                     RTVASIDKVNKIRALRDAGFTGQALEGKSLFGMGKEYVGGSKAFTTTGFGNRVKLAWNS
                     HVQDVAGASIKEAGISKGLNKVLDSGLTPDAIKRSLRGAMRNDGSIDPISWWSKGPQVA
                     QQVPGIAIDTHTQITDTGTPAAGRL"
     gene            6676..7329
                     /locus_tag="N1H47_RS35905"
                     /old_locus_tag="N1H47_35900"
     CDS             6676..7329
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572539.1"
                     /locus_tag="N1H47_RS35905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35900"
                     /product="hypothetical protein"
                     /protein_id="WP_016572539.1"
                     /transl_table=11
                     /translation="MALSPQSISITLDTPEGFHDLPLHLPAEVLDAALWELAQKIWPGG
                     TEFQRETTAIVYSDLTMALTADDVLHAAVALYETEDGAASTAHLLVHAKAVDPEAPEIV
                     TASFQEALSFDEHRNVARVDLPCGPAVLSLHATETEGSATLPALEFAQIELYVPAPVRG
                     WLIVLALTTPCFADLPRYTGILRQIGESLVVGPAQQETELSKAPVAGDVRAVFG"
     gene            complement(8408..9883)
                     /locus_tag="N1H47_RS35910"
                     /old_locus_tag="N1H47_35905"
     CDS             complement(8408..9883)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572540.1"
                     /locus_tag="N1H47_RS35910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35905"
                     /product="MFS transporter"
                     /protein_id="WP_016572540.1"
                     /transl_table=11
                     /translation="MSLISFLGCIDLTIVNTAAPQIQKDLGASVTDLQLIVNMFIVALS
                     MFMVTMGRLADSYGRRRVLYIGTVVFGLASLGAGFAPTTGWLIAFRFLQGAAGAILYTS
                     TGAIVQNAFPESQRGRAIGALYGVNGVGLAIGPMLGGVLVSAAGWHWVFWLNVPLVALA
                     LSLCSFSVRESRNEEATTGVDWPGLILISLGIPAVVLAFTLGGTWGWTSLPTLGLLAFA
                     LIVLIAFYLVEKRAADPIIRFSLFKHRAFLAAIVSDFALASFYATVLFLLPLYLDEVRG
                     YDGYATGALLLPCTAVMAVLSPFVGRLTDRYGPRKILIAGFTAFTVSALLFTQLTADTS
                     LFLIVVALVAMGLAWGSVLGPATVSALSSVPERQAGLAMGSSWTFHNLGGAIGLAAGIV
                     LYRVQAESHLTDTLSAKGVAIGPWTRDAVADPERAAELLKEHTSLNAHDITDVFNQMFA
                     HGTQSAMWMLVGTSAAALIILGLLSLTDRRQAA"
     misc_feature    complement(9752..9754)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9966..9983)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.11"
                     /tool="antismash"
     gene            complement(10001..10708)
                     /locus_tag="N1H47_RS35915"
                     /old_locus_tag="N1H47_35910"
     CDS             complement(10001..10708)
                     /GO_function="GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572541.1"
                     /locus_tag="N1H47_RS35915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35910"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_016572541.1"
                     /sec_met_domain="CDPS (E-value: 2.6e-34, bitscore: 117.7,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSYLVDGRTKANFGEAAKKLTLAGTRAILLVSVGQRYHEGDKLR
                     ATVELVNRSEFKQLTIAVADTLQRSNYIDASPEQAYARSLREGDEWLERNDKILGQLSV
                     PNEVLRWDEALKDPDYPQFRQRIERAYAEIAEYRQAVDSTIKKFIDRLTARTPEADTEK
                     AFKGCLEYLIEECPIIMPMWAHQGYDHVIYPQPMTAAMAESQRLFVTTEYPGKGGWLSL
                     RFKKRAAAADQLA"
     gene            complement(10716..11498)
                     /locus_tag="N1H47_RS35920"
                     /old_locus_tag="N1H47_35915"
     CDS             complement(10716..11498)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF047266.1"
                     /locus_tag="N1H47_RS35920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35915"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="WP_037634728.1"
                     /transl_table=11
                     /translation="MSITRRATFRELTHEDILALIEGTVLAVHIPGFAPAEVVTSARDH
                     LVDHPDKGGLSQDTTFQRIGFAYSEISDDASRERYHSEARDNIQRMRDLFSPYASPSDT
                     LRLLLEETWNPGASLLSVEGRKAFIGICRFQDQGVDLNPHTDALERNLPSTDAHELVAQ
                     LSANIYINIPHTGGELELWGTEPGEHAYNELKGERVWGLERDQLGPPKAVIKPAPGDLL
                     LLNPRQIHAVRPSSDEPRITLGHFIGYHGADRPLTLWS"
     misc_feature    complement(11421..11423)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    11611..11628
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.7"
                     /tool="antismash"
     misc_feature    11692..11706
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 23.18"
                     /tool="antismash"
     gene            complement(12119..12598)
                     /locus_tag="N1H47_RS35925"
                     /old_locus_tag="N1H47_35920"
     CDS             complement(12119..12598)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572543.1"
                     /locus_tag="N1H47_RS35925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35920"
                     /product="DinB family protein"
                     /protein_id="WP_016572543.1"
                     /transl_table=11
                     /translation="MGSFDVPLDDERTQLDAFIEEYRNAIELTLDGLTEEQARRQLVPS
                     ATTLLGLLKHVTWMQRVWFEECVGGTSRRELGLVPSPDASFQLSGDDTVASVTAAHREA
                     CATARTTIAGLPLDAVVTGHRTGPRTLRWVYLQVLRELAHHCGHADILREQVLAD"
     gene            complement(13393..13743)
                     /gene="trxA"
                     /locus_tag="N1H47_RS35935"
                     /old_locus_tag="N1H47_35930"
     CDS             complement(13393..13743)
                     /GO_function="GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="trxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572544.1"
                     /locus_tag="N1H47_RS35935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35930"
                     /product="thioredoxin"
                     /protein_id="WP_016572544.1"
                     /transl_table=11
                     /translation="MNTTETAVITVTDETFDQLVLHSTRPVLLEFWASWCGPCRQLAPV
                     LEHIAREQADRLTVAKLNTDENPATMIACNVLAAPTLQVYRGGELVKEMVGARPKRRLM
                     HELEDVLAHDQL"
     gene            complement(13781..14179)
                     /locus_tag="N1H47_RS35940"
                     /old_locus_tag="N1H47_35935"
     CDS             complement(13781..14179)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572545.1"
                     /locus_tag="N1H47_RS35940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35935"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_016572545.1"
                     /transl_table=11
                     /translation="MRIGELAERAGVSTRSLRYYEAQGLLRARRAANGYRDYGNEDLRI
                     VREIRSLLDLGFGLEEIRPFVECLRDGHETGDRCADSIAVYRHKIAELDACIAHLSEVR
                     QRVSGQLQRAIEVRTTDPRCEFSPCVSE"
     gene            complement(14365..14673)
                     /locus_tag="N1H47_RS35945"
                     /old_locus_tag="N1H47_35940"
     CDS             complement(14365..14673)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013006294.1"
                     /locus_tag="N1H47_RS35945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35940"
                     /product="hypothetical protein"
                     /protein_id="WP_016572546.1"
                     /transl_table=11
                     /translation="MSAALPRTIRAVDSDQLLLLEEEASRLRFSQRLPADWLREHIQAA
                     SAHYLFPVMEHWLAHRPDASPQWRCELLLMVRTGEMERSEARQGVPRHRGVRSRRAA"
     gene            complement(14910..15122)
                     /locus_tag="N1H47_RS35950"
                     /old_locus_tag="N1H47_35945"
     CDS             complement(14910..15122)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N1H47_RS35950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="N1H47_35945"
                     /product="hypothetical protein"
                     /protein_id="WP_016572547.1"
                     /transl_table=11
                     /translation="MTTCRTERPHPDWEVVLDHDRAEAEASRRRLVQLLSQDDAFGFGV
                     HFADQQLGTADAGHWRPWDDTTDNR"
     gene            complement(15241..15831)
                     /locus_tag="N1H47_RS35955"
                     /old_locus_tag="N1H47_35950"
     CDS             complement(15241..15831)
                     /EC_number="3.4.24.-"
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152088.1"
                     /locus_tag="N1H47_RS35955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35950"
                     /product="snapalysin family zinc-dependent metalloprotease"
                     /protein_id="WP_016572548.1"
                     /transl_table=11
                     /translation="MIKRIAALAALVPAMLGTSAGAPSAHPAAQATTSVVTLTYDASGA
                     GQWAGAIKQAVQNWNDAVHNVHLEPASSPGSADYVYEATSGWPQTTLGPIFPGGNGDVQ
                     LGQQAVDEGYDTTRITAHETGHILGLPDDYSGPCSELMSGHGPGTSCTNAKPNAAEAAQ
                     VDKNYAAGTPAVRPQHHQVVIDIWSGRTHTNPR"
     misc_feature    15879..15899
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.12"
                     /tool="antismash"
     gene            16435..17496
                     /locus_tag="N1H47_RS35960"
                     /old_locus_tag="N1H47_35955"
     CDS             16435..17496
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2OG-FeII_Oxy"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575715.1"
                     /locus_tag="N1H47_RS35960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35955"
                     /product="isopenicillin N synthase family oxygenase"
                     /protein_id="WP_016575715.1"
                     /sec_met_domain="2OG-FeII_Oxy (E-value: 5.2e-18, bitscore:
                     64.3, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRATAVDGVLDVPVIDISAWTDGTAADRAGIAGEIDQAARTVGF
                     MQIRGHGIPEAAGRAFAAALDGFFGLPMDEKKALCAPSPDVNRGYTPPRTEKLSLSLGV
                     PAAAEDLFEAFNVGAEAAAFPGLGLPEAHYPANLWPAVPGFRDAVTEWCAQAGGLARRL
                     TGIFAHALGLPVDYFAPFTDHSLDVLRMNHYLVPEQELVVDRDQMGMGAHTDYGIVTVL
                     WADRVPGLQILDTEGRWHDVLPEPGCLLVNLGDLLARWTNDQWLSTMHRVLPPTDASGR
                     VVRRRSAAFFHDGNWDAEISCLPGCVPVGADPLYPPTTVGRHLAEKLGGSRAGKPNANS
                     PREAARLLAARSD"
     gene            17608..18963
                     /locus_tag="N1H47_RS35965"
                     /old_locus_tag="N1H47_35960"
     CDS             17608..18963
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009071802.1"
                     /locus_tag="N1H47_RS35965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35960"
                     /product="solute carrier family 23 protein"
                     /protein_id="WP_020930305.1"
                     /transl_table=11
                     /translation="MALTPRRAPLRRPRPVPADAAPHPGLGRTLGLGVQHALVMYAGAI
                     AVPLMFGAGAGLDEAAVSTLVNADIFVAGIVTVVQSLGAGRFLGVRLPLVTGGSFVCVT
                     PMIMIARQYGMPAVYGSMIAAGLFGMLVAFPFARALRTFPPLVSGVVITVVGLALIGAA
                     PGMIAGPDPAAADYAPPAHLALAGGVIGFLLLLRRFLRGFLAQVSVLLALLAGTLAALP
                     MGLTDFSGVADADWWGLVSPFRFGAPTFPLAGVVSLCVVMLVVFAESTAQMIAVSEAVE
                     RPLTDRALGRGLAADGLSGVLGGAMNSFPDTVFAGNIGLTLMTGIRSRYVTAAGGVVMV
                     FLGTLPKLGEAIASLPQPVIGGASLICFATVAAVGINILRRAGLDQGDNLLIAAAAIGT
                     GMLPVVAPRLYHRFPEWWQLVFGSPSTAALVVALGLHCAFHRGRRRVEGAEV"
     gene            complement(18975..20381)
                     /locus_tag="N1H47_RS35970"
                     /old_locus_tag="N1H47_35965"
     CDS             complement(18975..20381)
                     /EC_number="3.5.4.32"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575307.1"
                     /locus_tag="N1H47_RS35970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_35965"
                     /product="8-oxoguanine deaminase"
                     /protein_id="WP_016575307.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.5e-60, bitscore:
                     204.1, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADTHHHARPDGTADPTDHCDLLVRDARLLVIDGDTEVPGGWIAL
                     RDGRVAAYGPAGSEPAGATRTLSAAGRLVTPGLINTHHHMYQNLTRAYAPAVNGTLFTW
                     LTTLYPLWAALDEEAVHLATYVGIAELLLGGCTTSMDHHYVHPRPRLIDAQIRTAQEVG
                     FRFHATRGSMTRSTEDGGLPPRSVTQTAEEVLADSERLVQTYHDAAPGALTQVALAPCS
                     PFSVTRELMTATAELAERLDVRLHTHLAEDPDEDAYCLETYGCRPVEYFESVGWMTDRT
                     WVAHCIHPTKEERARLAAAGVGVAHCPSSNMLIAGGTAAVREMRGLGMPVGIGCDGSAS
                     TDHASLWLETRSALLLGRYRGGPSAMTARDALDIATRGSARCLGRADELGQLRPGACGD
                     LVVWDTPAVALAGALTDPVEAWLRCAPSRAWTTVVGGRVLVDEGELQLSSLEEKLDEHA
                     RVARRMQGLV"
     misc_feature    20366..20380
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
ORIGIN
        1 gtcaatgacg acctggtagt tggtggagta ccggtagtct ttcgactgct cggcgatggt
       61 gtaatcgcgg gtggggatca gggtgccgtc cacgatcagc acggtgtcct tgcggaaccg
      121 cttgcgttgc tggagcgcaa gcgagggcct gaggtggtcg atgatgcgat cggcagtcga
      181 cttcgatacc ccgaacagtg gtgccagctg ccgcaccgtg aagttggtgc gccagtacgc
      241 ggcgaccagc aggacctggt cctccagcgg caggctctac ggccggccct ggcgaacggg
      301 gtctgcaccc tcgcgtcgta acgcgacaat ccgcttgccg aactgtcgcg ggctcagtcc
      361 gctgaacggg gctatccagg caggctccga cgccgtgatc acactagtca ctgcatgatc
      421 attccaccgc ttcaggagct ccctgctcaa acgcgaggcg gcagtgttcg acctgctcgg
      481 ccacctgctc catgagccag cgcatgatct cgtaggggat gacgtgctcg tcgtggctgt
      541 ggatatggac ggtcggctcc aagctcgggt cctcgtcggg tatcaccgcc accatgaagg
      601 cagccccagg caggtgggtc tgtgcgttgg gaacctcagc ccacgcagct ggcgccggca
      661 cggcctcgct cagctccaca caccaggcgt cgttcggcaa cgcatagtgg aactggacgg
      721 cgtaatggcg gcctgcatga atgcgcagct ctggcatgcc cgcaggctgc cacagtcgcc
      781 acgccggagt ctcgcgagta tccgcccagc acctggtgcc gccgccccac caaccatttg
      841 tgcacgctgg agcgctgggc cgagacagga agacaccggc cgcagccggc tgcggctcca
      901 cgtcgacaag aaggccgcta cccagctctc catccctcag ctcctgtcca agacgaacgg
      961 ccacaccgag atcgagtcga agaaggccat gcgggcgcgc gggctgaaat caccagaccg
     1021 agctgagtcg gtgctgctgt ccatttacga gcccgagccg ttgcacaggc cgcggcaccg
     1081 cggcctcctc aactgaagag caccccccat cgtgggtccg ccagtcacag ttcgattcgg
     1141 ccatccttgc cttccgggcc ggttggcatt ccagccaaca atcgtgccaa cgggctcggt
     1201 ctggatagat atgagggtgg ttggaagaac attctccgtc agctgaccct gcccgccctg
     1261 acgtctcact gtggcgcatt actttccata tcggactgtt gccgctggcg tctgccatgc
     1321 tctcgccggt tcccactgtg gagccaggtg catcgcgcct tcgggggctg tgcaccttcc
     1381 gaatcaaggg gagggttgtt cgtggagaac aagcagagat caacgcgccg taaggcagca
     1441 ctggtcgcag gggtggtcct ggcggccacg gttgcaggaa ccgttccgtc ctgggccgag
     1501 gggagctggt cgagctacat gtccaactgg accaacggtg ccgaatctcg ccgttggcag
     1561 gacaaccact cggacggaaa cgcgaccacc atcggtttct ccggctgcaa cttcggtggc
     1621 gccggcgccg tgaacatcac cctgtaccgt gcggtcgact actggcccga cgacgctcag
     1681 ggaatgaagt tcatggactg cggcaccacc tcctggggcg cgatgagcat cgcggggagc
     1741 tactacttcg cctatggagg caaccacaca atcaacgtga acaacgtcgt ggtcaagtac
     1801 tagccgaacc cctgtcgccc ggcgtcccca gagaccctgg gagcgccggg cgctcagctc
     1861 tttcctacct cacctggaag caccgtgccg atcagtatca gtgactgttc attcatgtat
     1921 cgcagagggt tgcctgtcct tgaggggctg agcctgtccc tcggttacgg tgcaaccgtc
     1981 ctgctcgggc ctaacggcgc cggaaagtcc accttgctcg ggctcgcagc atccgcgttg
     2041 cgccccgcct ccgggcatgt ccgtatcggc gctctcgaca cccgaaaccg caaggacgtc
     2101 aaggagtacc gccgaaaggt cggttggctc ccccagcagg tcaaagcgat ccccggactg
     2161 cgggtccgcg agcaggtggc acacgcaggg tggctgaagg gcatgtcccg tatccaagcg
     2221 tgggaggcat ccgcgggggc tttggaagcg gttggtctca ccgatttgtc agcacggagg
     2281 agttcagagc tgtcaggtgg gcagaagcgg cgcctgggaa tcgcacaggc actggttcat
     2341 agcgccgagg tcgtcctgat ggatgagccg acggccgggc tcgaccccag acagcgagcg
     2401 acgttcaggg acctggtcgc gcggctgagt tcaacggtgg ccgtggtggt ctcaacccac
     2461 cagaccgaag acctcgccga catctaccag agcgtggtcg ttctcgacca agggcgtgtc
     2521 aggcaccaag gggctgtcag ttcctttctg gacctggccc ctgcaggttc tcccagagag
     2581 cgacaggcag aagccgccta cgccagcatc tgcacggtgg aggcgtgagt atgtacttga
     2641 ggacactcct gcggacctcc actgcaccgc gagcagcctt cgttctggtt ccctggcttc
     2701 tcgcctacag cgggaacatc agcaactgga tcaccaccgg atactgggcg tcggtcaccg
     2761 cgcagagcag cttcctgctg gggttcatcg ccccggcgtg tgcagcgtgt gcagcgtggg
     2821 aaggtgcgcg gatcaagcgt tcggcgatgc tgggcggagc cccttctcgg tcccggctgg
     2881 ccatcgcttt ttcggtgctg tggcccgtca tgctcctcgg cgtcctttcg gtcgtcttgg
     2941 gggtggcggt ctcggcttcg caggcttcag gactaccccg atggtcgtcc ttcgtcatgc
     3001 tcaccgttga agcctgcgtg gtggtcgcgc acaccactgc gggatatgtg gccgggctga
     3061 ctcttccgcg gctactggcc gcccccgcgg ccctcgtcgc cagcttcgtg tggatggcct
     3121 acccggctgc catgaacaac ccgccatggc tgcggcaact caacggccac aacttcaatg
     3181 aatgttgcgc acttgaccag gtgcctgacg taaggggatt cgctgctgcc gccgtcgtgg
     3241 cagtcggtgt ggcaagcgcc tgcgcactgt ggatcaacct gcacggcgtg ttgcggcttc
     3301 tggccccagt ttctgtggga ctggctctag tcgtaggttg cgtcgtggcc actccaatgg
     3361 ggtaccaggc ggcgcgacct cgtgacctcg ccgaactcga ctgccgtacc ggaccgagcg
     3421 ggatctgcct gtggccggaa caacacggcg ccgccaaaga aatagaggag tggggcctcc
     3481 aggctcggcg gagcctggag gcagccggag tgcgtcccgc gcgcaaggtc aaagtgatga
     3541 ccgttgcgcc ccgcccaggc gacgtcgtca ccgtcatggc gttcagcgcc gttccccagg
     3601 acattccgtc gtgcgcccgt accgggcaat ggccgggcag ccaggcgacc ggaccggtga
     3661 tggcatggct ggcgctcact gctggggcgc agccccagga ccttgagggg cactacatcg
     3721 agggcgacgt gcacctcgca cgaaaggtac gccgacttcc cctggccgga cagcaacgct
     3781 ggttccaccg caacgtcgcc acactgaccg gatgcgacaa ggcccccgac ctcgcccccg
     3841 aacacttcgt cgcaggtgct gccctgtgat cttctgggca cgtgtccgga tgctgcccgc
     3901 ggtatgcggc gcactggcaa tcgtaatgat cgcaggagca gcagctccgt cagtggcatt
     3961 gccgatccca ctggtattcg gaacggtgtc gttccccttg ccagtgcctc tcctgctgcc
     4021 actgctgccc gtatgtctga tgctgcacgg gcagtccagg ggggacttgg aagcggagaa
     4081 ggtagcagcg cggccagttg gggtgtggga cgcattgacc atggtcggct tcgtggcgct
     4141 ggcttgcgtg gtgggtgcat tcgaggcgtg gtccggccgt acgacggggc tcgcgatggc
     4201 ccgggacttc gccggctacc tgggcctggc cctcctgatg cggcgagtcg gcggaccagg
     4261 cgccgccaac atcgcagtcg cattgttccc gttcgcgtgc gcgtccttcg gtatgaggcc
     4321 cagcggacaa ccacgttcgt gggcatggcc attccacgac cccggatcgg tcccggctgc
     4381 cttgatggca atcgtcctct tcctggcagg tctggcgctg tctcggcacg ctcctttgat
     4441 caagcgatgg ggcgaagaag aatagggcgg cttccccgag caagttcacc aggtcgagcc
     4501 gctgttcccg ctaggcgaac gccactcgct gacggacgat cccctggagt tgcgcggctg
     4561 atgaaggcgc tcttgcgctg accgagccca tcgctggctc ccgtcgcgcc acgctcccac
     4621 ccatcgcggg cccgttcctc acagctctcg atcaggccac tcgaaccgcc gtcgcgcgtg
     4681 tccgcgggca actggcagct gccacgtcag cagggacagc cgccgaaagc ctcagcagga
     4741 gactgagggc cttggagcgg tccagcacct cgccctgcca acacccaggc gctggcaaac
     4801 cgttgggcaa gcaagggtaa tgtacgaagg cggtcatgcc gaagtacgga caccaccagg
     4861 ggggcgcatg ggcggctatt tcaaggttga aacagatggg ctcgggcgcc tgctgaagga
     4921 tctgcacgac agtcaggaca atatgcgcaa ggcgctgggt gctctcaagg acaccggacc
     4981 gaagtcgatg ggggcggagg ctcttgacaa cgcctgcgac gagttccacg acagctggga
     5041 caatgcgatc aagaagatcg ccgacggtac ccaggccatt gaggagaagc tcaagcaggt
     5101 caagcagaac tacgagtcgc tggagcatgc cctgcgcgac gccttcgcga agaacgccaa
     5161 gtagccccgc gcagcttgta ttcagcaaga ccgtaattct cttcaacctc caacaggtga
     5221 tttcatgact acgcgggact tccccgctct cggcttcaac ccggcgcccg gcgagctgag
     5281 ttccgtcgac gacgtcacgg gcaagctcga tgcagccaag cgctccctgg attctgccca
     5341 tgccgtactg tcccgcatcg gcaagggcga cggcgagtgg cagggtgacg cagcgaacgc
     5401 gttcgcaaag aacgtcggcg acttgccgaa atacgtgagt gacagtcgcg acgcgatgcg
     5461 tgatgccgtc acccagctcc gatcctggca tacagcgctc tcctcgtacc aaagcaaggg
     5521 gattcagtac gagtcggagg ccgcggcggc caagcagacg gtggccacgc gcaagaccga
     5581 gagggagcac gcggtacagg cctacaacga ggccgccgct catccggacc tacgccttgc
     5641 cggcacctac tatgccgacc agactgccct ggatgccgcg cagaagagga tcgacgcagc
     5701 aagcgaccga ctggacaagg cagatagagc tctcgacgcc gcccgcagcc gccttgattc
     5761 cgccaccgag gaactcgaga gcatcgtcaa gaaggctgag gaactcctcg gccaccacca
     5821 ggacgaggcg cgtggcatcg ccgatcgcat tcggcgagcc acggagaacg cgccggaccc
     5881 agggttctgg gagagccttg gtgacttctt cacccgcatg ggacacagca ttcaagaatg
     5941 gtgcgctaag cacgctgacc tgctgaagga gatcggcgac tggctttcaa tcgcgtccag
     6001 catcctgggg gtcgcctcgc tcctgaccat gtggtgcccg ccgctctccg gcgccctggc
     6061 gctcgccagt gcaggagctt cccttggtgc cctcgccact catggagcgg cgaagctcgg
     6121 gggcgccgac gtaggggtta tggacctggt gggggacgga atcggagtgg tcccgttcgg
     6181 gaagttgggc gcggtcgcga tgaaaggggc caaagtgccc atgaagctgg tgcaggtgga
     6241 aggccgcacc gtcgcctcga tcgacaaggt aaacaagatc cgcgccctgc gtgacgccgg
     6301 tttcaccggt caggcgctgg aggggaagtc gctcttcgga atggggaagg agtacgtggg
     6361 cggcagcaag gcattcacca ccacagggtt cggcaatcgc gtgaaactgg cctggaacag
     6421 ccatgtccag gacgttgctg gcgcgagcat caaggaggca ggaatcagca agggcctgaa
     6481 caaggtcctc gacagcggcc tcactcccga tgcgatcaag aggtccctgc gcggtgccat
     6541 gaggaacgac ggctccattg acccgatttc ctggtggtcc aaaggtccgc aggtggcgca
     6601 gcaagtgcca ggcatcgcca tcgacactca cactcagatc accgataccg gcacaccggc
     6661 tgcggggagg ctctgatggc gctgtccccg cagagcatat cgatcaccct ggatactcct
     6721 gaaggattcc acgatctacc gctgcacctc cctgcggagg tcctcgacgc cgccctgtgg
     6781 gagctggcac agaagatctg gccaggtggt acggagttcc agcgagaaac caccgcgatc
     6841 gtctactccg acctcaccat ggcgctgacc gccgacgatg tcctgcacgc ggctgtcgcc
     6901 ctctatgaga cagaggacgg tgccgcaagc accgctcatc tcctcgtaca cgcaaaggct
     6961 gtggacccgg aggccccgga aatcgttacc gcctccttcc aggaggcgct ctccttcgac
     7021 gagcaccgca acgttgcgcg ggtggacctg ccctgtggcc cggcggtgct ctctctgcac
     7081 gccaccgaga cggagggctc ggccacccta ccggcactgg agttcgccca gatcgagttg
     7141 tacgtccccg ctccggtccg agggtggctg attgtgcttg ccttgacgac accatgtttt
     7201 gccgaccttc ctcggtacac aggcatcctg cgccagatcg gagagtccct ggtggtgggc
     7261 ccagcccagc aggaaaccga gctgtcgaag gcgccggtgg ccggtgacgt gcgcgcggtg
     7321 ttcggttaag cacgagcatg ggtgaacgac ccaggacgcg tcgtgcctgt gggtacacat
     7381 cgtggcaccc ggtcgcagtc cctacccctc ggggctgtcg ctcgcacccg ttgcaccggc
     7441 cttcctcgcg cacacgttgg gatgcgagtc atcatctcgc ctattgaact ctgccatcgg
     7501 gaatggcatc cagaaccgac gcaacgaggc aggacaccat gacattggtc ttcacccgtc
     7561 acacggacgc taaatgttac gagctacgcc cccgaggcgc agcagccgtc tacgtgctgc
     7621 gcggcgtccc tgacagttgt ccagtccccc agggacataa gcctcgcttc accctcgctg
     7681 ccgaccctgc cggtacctcg ccgctggccg tgatcgcccg taagaacggc ggtgggctag
     7741 tcgtgcttac accagaccac gagcggctgg ccgaactacg cctgccacca aggaaaaagc
     7801 ggtggcgccg cacatacgag atccacctac ccgacggcat cgcactacgt gggcgggagg
     7861 ggacagtgcc atcgctgctc ctgtgtctgg ccctgctgcc gctcaccctg ctgtacatgg
     7921 ttgccctgac actcgccgac tccccagccg gcaccaccac cgccccactg aggacggcct
     7981 ggaagcaatc tggcaaaccc ttcagtcggg cagccctgtc cgagtccgca cgtggccggt
     8041 tccgcatcgg ccgcgaaggg ctcgaccaac gagtcgctta tgcacaggca gtggcgaagt
     8101 actgggagcg ttaatcttcc cagcacacgc gggggtggct cgttcagcgt cacgcagaag
     8161 gcggcgcatt ccctgtcgtc cccgcacgcg cgggcgtact tccgtcgcag tgcacacccc
     8221 acgcgccttc accgagtcgt ccccgcaagg gcggatgtcg tcccgtcacc tggagagact
     8281 ggcggtcagt tggccgtcgc agtggccgag ttgctgtccg gcgtcactgc gggctcctgg
     8341 tgagtgtgcg gaacgtcctg gaaggcgacg aggggagtgg ccggatgagg ccgctcccct
     8401 ctgcgtttca ggctgcttgg cggcggtcgg tgaggctcag taggccgagg atgatcaggg
     8461 cggccgcgga ggtgccgacg agcatccaca ttgccgactg ggtgccgtgc gcgaacatct
     8521 ggttgaagac gtcggtgatg tcgtgtgcgt tgagggaggt gtgctccttg aggagttcag
     8581 cggcgcgctc cgggtcggcc acggcgtccc gggtccaggg gccgatggcc acgcccttgg
     8641 ccgacagcgt gtcggtgagg tgggattcgg cctgcacccg gtagaggacg atgcctgctg
     8701 ccaggccgat ggctccgccg aggttgtgga acgtccagga ggagcccatg gcgaggccgg
     8761 cctgacgttc cggtaccgag gacagggcgg agacggtggc ggggccgagc acgctgcccc
     8821 aggccagtcc catcgcgacc agcgccacca cgatgaggaa gagggaggtg tcggcggtga
     8881 gttgggtgaa cagcagggcc gagacggtga atgcggtgaa gcccgcgatg aggatcttcc
     8941 gggggccgta gcggtcggtc agccgcccca cgaaggggga cagcaccgcc atcaccgccg
     9001 tgcagggcag caggagggca ccggtggcgt atccgtcgta gccgcgtact tcgtcgaggt
     9061 agaggggcag caggaagagc acggtggcgt agaaggaggc gagtgcgaag tccgagacga
     9121 tcgcggcgag gaaggcacgg tgcttgaaga ggctgaagcg gatgatgggg tccgcggcgc
     9181 gcttctccac gaggtagaag gcgatgagca cgatcagagc gaaggcgaga agtcccagcg
     9241 tgggaaggct tgtccagccc catgtgccgc cgagtgtgaa agcgagcacg acggcgggga
     9301 tgccgaggct gatgaggatg aggccgggcc agtccacgcc ggtggtggct tcctcgttgc
     9361 gggactcacg gacgctgaac gaacacagcg acagtgcgag tgcgacgagc ggtacgttga
     9421 gccagaacac ccagtgccag ccggcggcgg agacgagcac cccgccgagc atgggcccga
     9481 tggcgagacc gacaccgttg accccgtaca gggcaccgat ggcccggccg cgctgggatt
     9541 cggggaaggc gttctggacg atggcgccgg tggaggtgta gaggatcgcc ccggcggcgc
     9601 cctgcaggaa ccggaaggcg atgagccagc cggtggtggg ggcgaagccg gcgccgagcg
     9661 aggcgagtcc gaagacgacc gtgccgatgt agaggacacg acgccggccg taggagtcgg
     9721 ctagccgccc catggtcacc atgaacatgg ataaggcgac gatgaacatg ttgacgatga
     9781 gctggagatc ggtgacggac gcaccgagat ccttctggat ctgcggggcg gccgtgttca
     9841 cgatggtgag atcgatgcag ccgaggaagc tgatcaggct caccccggcg aaggcccacc
     9901 acctgcggtc cgatggggct ttcgtcgctg acttgggggt ggtggtcgat gacgtcacag
     9961 tgtcgtgtcc tctgtaccgg atggtgatga tcgtggagct ctaggcaagt tggtcagcag
    10021 cggcggcccg cttcttgaac ctcaaggaca accagcctcc ctttccgggg tattccgtcg
    10081 tgacgaacag ccgttgggat tcagccatgg cggccgtcat cggctgtggg tagatgacgt
    10141 ggtcgtagcc ctggtgtgcc cacatcggca tgatgatggg gcactcctct atgaggtatt
    10201 ccaggcatcc tttgaatgcc ttctcggtgt ccgcttccgg ggtacgtgcc gtgagtcggt
    10261 caatgaactt cttgatggtg gaatctaccg cctggcggta ctctgcgatc tccgcgtatg
    10321 cgcgttcgat gcgctgcctg aattgagggt agtcggggtc cttcagtgct tcgtcccacc
    10381 ggagcacctc gttgggcaca gaaagctggc ccaggatctt gtcgttgcgt tcaagccatt
    10441 cgtccccctc gcgcagggaa cgtgcgtatg cctgctcggg agatgcgtca atatagttgg
    10501 agcgctgcaa ggtgtcggcc accgcgatgg tcaactgctt gaattcgctg cggttcacca
    10561 gctccactgt ggctctgagc ttgtcaccct cgtgatagcg ctggccgaca ctcaccagta
    10621 gaatggctcg cgtgccggcg agggtgagtt tcttggcggc ctccccgaaa ttcgccttcg
    10681 tacgtccgtc gacgaggtag gagttcattc ctgcctcagc tccacagggt gagcggccgg
    10741 tcggcaccgt ggtagccgat gaaatggccc aaggtgatgc ggggctcgtc gctggacggc
    10801 cgtaccgcat ggatctggcg cgggttgagg agcagcagat cgcccggcgc aggcttgatg
    10861 accgccttcg gcgggcccaa ctgatcgcgt tcgaggcccc agacccgttc ccccttgagc
    10921 tcgttgtagg cgtgctcgcc aggttcggtg ccccacagtt cgagttcgcc gccggtgtgc
    10981 gggatgttga tgtagatgtt ggccgagagc tgtgcgacca gctcatgtgc gtccgtcgag
    11041 ggaaggttgc gttccagggc gtcggtatgc ggattgagat ccactccctg gtcctggaac
    11101 cggcagatgc cgatgaacgc cttccgccct tcaacgctca gcaggcttgc cccggggttc
    11161 caggtctctt cgaggaggag gcggagagtg tcactcggcg acgcgtaggg ggagaatagg
    11221 tctcgcattc tttggatgtt gtcccgggct tccgagtgat aacgctcgcg ggacgcgtca
    11281 tcgctgatct cggagtaggc gaagcctatg cgctggaacg ttgtgtcctg actcaggcca
    11341 cccttgtccg ggtggtcgac caggtgatcg cgtgcggatg tcacgacctc ggcgggggcg
    11401 aaccccggta tatgtacggc taataccgta ccttcgatga gtgcaagaat gtcctcatgg
    11461 gtgagctcgc gaaaagtcgc ccgtctcgta atagacattt cttcccttcc gggtcctcgg
    11521 gaaatgggtg gcggcccttc ttcgcatttc cgcttgagtt tgcttcgctc ccactacatc
    11581 tgctggccgc gcaacaggtc aatggactta atgtgagtgc aatgtgaatg taaagaatcg
    11641 cggcttgaat cagtggacta aggcgctgtt gaattggcct atttcatcgc ctcggagcgg
    11701 tctcatcccg gctgcgcgca tctctgccga gtcgcatcca tcgaggtcag agacgcgaaa
    11761 ttggggggaa gcgaaggctg gcacaggtgc tcctggccga gatcgggctg gcgcgttctg
    11821 tgcgccgatc gggatcccgc cgaaagagac gcgacatact gccgcaacgg tgtttggtgt
    11881 cgaccgttcc gccatcagcc gggtcgtcgg ccagatccga ccgtgcatgg gcgggcggag
    11941 ccgtgcggtt caaggcaccg gcccgatccg tgccggcgaa ctctgggcgg cgtgttcgcc
    12001 tacgcccagg ccgagggcag cgagttgcgc cttgacgcca ccgagatccg ggcccgctgg
    12061 ccggcgaccg gccgcggcgg gcgccgtgcg ttcacctcgg cagacgtggt ctcaggactc
    12121 agtcagcgag tacctgttcg cgcaggatgt cggcgtgtcc gcaatggtgg gccagctctc
    12181 gcagaacttg caggtacacc cagcgaagcg tgcgcggccc ggtccgatgg cccgtcacga
    12241 cggcgtccag tggcaggccc gcgatcgtcg tccgggccgt ggcgcaggct tcccggtgcg
    12301 ctgccgtgac cgaggcgacg gtgtcgtcgc cggagagctg gaaggatgcg tccggactcg
    12361 gtaccaggcc gagctcgcgg cgggacgtgc cgccgacgca ctcttcgaac cacacccgct
    12421 gcatccacgt gacgtgcttg agcagaccga gcaacgtcgt tgccgacggg acgagttggc
    12481 ggcgggcctg ttcttcggtg agaccgtcga gagtcaactc gatggcgttg cggtattcct
    12541 cgatgaatgc atcgagctgg gtgcgttcgt cgtccagcgg tacatcgaac gaacccatca
    12601 gagtctcccc tcacaccgta ggccgaggcc catggcaact cgcgcgggcg acggcccgcg
    12661 gcgacgtcga caatcctggt cgcacgactc ttgccgcacg agtcgacgcc aggcaatccg
    12721 tgcacagccc gaggtgagca gccggcgcac agtggctgtg tgcggtcgag cgcagtccga
    12781 gaagtgcgca ccgcagcagc caggatacgg tgcgttcgac gagccagcgg tggcggccga
    12841 gcgaggtctc gtcctcggtc ccacgacgcg cgctgcggac cttgggcccg tgctggtgct
    12901 ggtgcgggtg gtgacggcga cggaggtggt cgtagccctt ggcggcgatc cgccccgagt
    12961 tgcggggcgg atcgcgccgg ggacgcccgg tgttcagtgc gaacgcgatg ccgagtgcgc
    13021 accgtcgtac gcctcggccg agtggcacat cgctcgacgt ccggacggcc accggcgttt
    13081 ccctcggctc gctcggcgac ccgagaacgc cccggagccg cgggactggt gggcaggacc
    13141 gctgagcgcc acggtggggc tcggccgctg gcgacggtgg cggacgtgtc ctgcctgaac
    13201 cggttggctg ggccgtaggt cgcttggtca gtggttctcg cggcgttcgg ctgttcccac
    13261 gcgccgggcc tggcttgtgt cgtcgcccgt gtcgaccggc gcatcctcgc catggcggcc
    13321 gtcgtctggc gcaacaactt gactggcgcg caagtaactt ggtcgctggt cgcctatgac
    13381 caccgaccgg ccctacagtt gatcgtgcgc caggacgtcc tccagttcat gcatcagccg
    13441 ccgcttcggt cgcgcgccta ccatttcctt caccagctcg ccaccgcggt agacctgcaa
    13501 ggtgggagcg gccagaacgt tgcaggcaat catcgtggcg gggttctcgt cggtgttgag
    13561 cttggcgacg gtcaggcgat ccgcctgctc gcgggcgatg tgttcgagga ccggtgcgag
    13621 ctgtcggcaa gggccgcacc aggatgccca gaactcgagg aggacgggcc gtgtgctgtg
    13681 cagtaccagc tggtcgaagg tctcgtcggt gacggtgatg acggcggttt cggtggtatt
    13741 cacaggtggt gtcctttgct cttgggcggg ccgggctgga tcattcggaa acgcaagggg
    13801 agaactcgca gcgcggatcg gtggtccgga cctcgatggc ccgttgcagt tgtccggaga
    13861 cccgctgacg cacctcgctc aggtgggcga tacacgcgtc cagctcggcg atcttgtggc
    13921 ggtagacagc gatggagtcc gcacagcgat cgccggtctc gtgaccgtcg cgcaaacact
    13981 ccacgaaggg ccgaatctcc tccagcccga agccgagatc cagcagcgag cggatctccc
    14041 gaacgatccg caggtcctcg ttcccgtagt cgcgatagcc attggcagcc cgccgggctc
    14101 gcagcagccc ctgcgcctcg tagtagcgca acgaccgagt gctcaccccg gcacgctcgg
    14161 ccaactcccc gatccgcatg gtggctcctc cctggttcac ccgagacgct agaccttgac
    14221 accggcgtca aggccagcgc tggggccagc atgccgccgg gaggtcgaga tcggacgatg
    14281 ttttggacca agtcatccag aagttggtgt gactgctggc ctggtgccca cggaccgtgg
    14341 cggctggctc cttgtgcctg cccgtcacgc cgcgcggcga gaccgtacgc ctcggtgcct
    14401 gggcacgcct tgacgggcct cggacctttc catctcgccg gtccggacca tgagcaacaa
    14461 ctcgcaccgc cactgcggtg acgcatccgg acggtgagcg agccagtgct ccatcaccgg
    14521 gaacaagtag tgcgctgagg ccgcctggat atgctcccgc agccaatcgg ccgggaggcg
    14581 ctggctgaac ctcagccgcg acgcttcctc ctccagcagg agcagctgat cggaatccac
    14641 ggcgcggatc gtccgcggca gcgctgctga catgctgcca tcgtgtcacc agatggcgcc
    14701 ggtgcgaccg cctcgcgccg acgaatgggg gcgcttgccg gcctcgggcc ggggctgcct
    14761 gcggtgcgag gaacgggcgc tcgaccgtcg ttgcgtagcc cagcacggcc gtcgtagccc
    14821 ggtgcgggag ccgcagttcg acgacgtcga tgacgaccag gagttggtgt tcgacgtgct
    14881 tcatgtcgag gccgcagcgg gtgggaggct taccggttgt ccgtcgtgtc gtcccaaggg
    14941 cgccagtggc cggcgtccgc ggttccgagt tgctggtcgg cgaagtgcac gccgaagccg
    15001 aaggcatcgt cctgggacag gagttgcacg agtcggcggc gtgaggcttc ggcctcggcc
    15061 cggtcgtggt cgaggacgac ttcccagtcg gggtgcggcc gttccgttct gcaggtggtc
    15121 atggagcaga caggccgttt cgccgtcgct ccgcgcgtct tgctgttgct ctacgccggt
    15181 ctaccgccct gtaggccggc gtaggccgcc ggtgttgagt gggtctgact cgctggccag
    15241 tcagcgtggg ttggtgtgcg tccggccgga ccagatgtcg atcaccacct ggtggtgttg
    15301 cgggcgtacg gctggtgtgc cggcggcgta gttcttgtcg acctgggccg cctcggccgc
    15361 gttcggcttg gcgttcgtgc aggacgtgcc ggggccgtgg ccggacatga gttctgagca
    15421 gggcccgctg tagtcgtcgg gcagcccgag gatgtgcccg gtttcgtgcg ccgtgatccg
    15481 ggtcgtgtcg tagccctcgt cgaccgcctg ctggcccagc tgcacgtcac cgttgccgcc
    15541 ggggaagatc ggccccaacg tggtctgtgg ccacccgctg gtcgcctcgt agacgtagtc
    15601 ggccgagccg ggggaactcg ccggctccaa gtgcacgttg tgcacggcgt cgttccagtt
    15661 ctgcacggct tgcttgatcg cgcctgccca ctgaccggca ccactggcgt cgtaggtcaa
    15721 ggtgaccacg gaggtggtgg cttgcgccgc ggggtgcgcc gaaggggcgc cggccgaggt
    15781 gcccaacatg gccgggacga gcgccgccag ggcggctatt cgcttgatca tcggactgat
    15841 acgcctcctt gggtttccgt tgctgtccga agtaaacgag ttcgtcgcgg acacgacaac
    15901 ctctctgtcg gcgatcgggt ccggttgttg ccaagttggc tcaaatggag aggagttgac
    15961 agtgggtagg gtgggggaag gagggcgagt gtcagtggcc ggtcgtgacg gtgggagatc
    16021 gagcgccgtc agcccgcctt gcggggcggc tgctgcggat tgcgccgggc tcgcctgcga
    16081 tcttgagggg agttctgggg ctggcgggtt ggtccggaag cagtacgcgc cgggatcgat
    16141 ccggtgccgc cgagttgggt cggccggggc gtcacgcggc gcaggtgccc ccgggcgggg
    16201 atcgtggggg acgcgggcgg cccggtggtc gttcggtatg cggcgcggcc tcctcgcata
    16261 caggggaggc gaatcggcat ctcggccaac gggcggctgg tttcggcttg ttcgccgcgg
    16321 ggtcgttaac aggacgttca tcaaactgtt gaagcggata ggggtgggtg ggcgccgcgg
    16381 gggaccgcgg agcgccgccg gagaggaccg agcgcgacgg aaggacggca cgcgatgggc
    16441 agggccacgg ctgtggacgg ggtactcgac gtacccgtca tcgacatctc cgcctggacg
    16501 gacggcaccg ccgccgaccg ggccggcatt gcgggcgaga tcgaccaggc ggcgcgcacc
    16561 gtcgggttca tgcagatcag ggggcacggg attcccgagg ccgcggggcg ggcgttcgcc
    16621 gcggcgctgg acgggttctt cggcctcccg atggacgaga agaaggcgct gtgcgccccg
    16681 tcgccggacg tcaaccgcgg ctacaccccg ccgcgcaccg agaagctcag cctgagtctg
    16741 ggcgtccccg cggcggccga ggacctcttc gaggcgttca acgtcggtgc ggaagcggcc
    16801 gccttccccg gcctgggcct gcccgaggcg cactatccgg ccaacctctg gccggcggtg
    16861 ccggggttcc gggacgcggt gaccgagtgg tgtgcgcagg cgggcgggct ggctcggcgg
    16921 ctgaccggga tcttcgcgca cgcgctgggg ctccccgtcg actacttcgc cccgttcacc
    16981 gaccattcgc tcgacgtgct ccggatgaac cactacctgg ttcccgaaca ggagttggtc
    17041 gtcgaccgcg atcagatggg aatgggcgcc cacaccgact acggcatcgt caccgtgctg
    17101 tgggccgacc gggtccccgg gttgcagatc ctcgacaccg aggggcgctg gcacgacgtc
    17161 ctgccggaac cgggctgcct gctcgtcaac ctcggtgatt tgttggcccg ttggaccaac
    17221 gaccagtggc tgtcgaccat gcaccgggtg ctgccgccga ccgacgccag tgggcgcgtg
    17281 gtgcgccgcc ggtccgccgc gttcttccac gacggcaact gggacgccga gatcagctgt
    17341 ctgcccggct gcgtcccggt gggggccgac ccgctgtacc cgcccaccac cgtcggccgg
    17401 cacctcgccg agaagttggg cggctcgcgc gccgggaagc ccaacgccaa ctcgccgcgc
    17461 gaagccgccc ggctgctcgc tgcccgcagc gactgacatc aacgcgcccg taccgcaggt
    17521 cagttgtgac cggccccgcg ccgcaccggc agggggcggg tgctttcccc ccaccgcccg
    17581 gcccctccgt gcccgagagg ttctgtcatg gccctgacgc cacgccgcgc gccgctgcgc
    17641 cgcccccgcc ccgtcccggc agacgccgcc ccgcaccccg gtctcgggcg gaccctgggc
    17701 ctcggggtgc agcacgcact ggtgatgtac gcgggcgcga tcgcggtccc gctgatgttc
    17761 ggcgccggcg ccggactgga cgaagcggcg gtcagcaccc tggtcaacgc ggacatcttc
    17821 gtcgccggga tcgtcaccgt cgtgcagagc ctgggtgccg ggcggttcct cggcgtccgg
    17881 ctgcccctgg tgaccggcgg ctccttcgtc tgcgtcaccc ccatgatcat gatcgcccgg
    17941 cagtacggaa tgcccgcggt ctacggctcg atgatcgcgg cggggctctt cgggatgctg
    18001 gtcgcgttcc ccttcgcccg ggcgttgcgg accttcccgc cgctggtcag cggggtggtg
    18061 atcaccgtcg tcggactggc gctgatcggt gccgcccccg gcatgatcgc cgggccggac
    18121 cccgcggcgg cggactacgc cccgcccgcc catctggccc tggccggcgg ggtgatcggc
    18181 ttcctgctgc tgctccggcg gttcctgcgc ggcttcctgg cccaggtgag cgtgttgctg
    18241 gcgctgctgg ccgggacgct ggcggcgctg ccgatgggac tcaccgactt ctccggcgtc
    18301 gccgacgcgg actggtgggg gctggtctcc ccgttccgct tcggggcccc caccttccca
    18361 ctcgccggcg tggtctccct gtgcgtggtg atgttggtgg tgttcgccga gtcgaccgcg
    18421 cagatgatcg cggtcagtga ggcggtcgaa cggccgctga ccgaccgggc gttgggccgc
    18481 ggtctggccg ccgacggcct gtccggggtg ctcggcggcg ccatgaactc cttccccgac
    18541 acggtcttcg ccggcaacat cggactgacc ctcatgaccg gcatccgcag ccggtacgtc
    18601 accgccgccg gcggcgtggt gatggtgttc ctggggaccc tgcccaaatt gggcgaggcg
    18661 atcgcctccc tgccccaacc cgtgatcggc ggggcctcgt tgatctgctt cgccaccgtc
    18721 gccgcggtgg gcatcaacat cctgcgccgg gccgggctcg accaggggga caacctgctg
    18781 atcgcggcgg cggcgatcgg caccggcatg ctcccggtcg tcgccccgcg cctgtaccac
    18841 cgcttcccgg agtggtggca gctggtgttc ggcagcccct cgaccgcggc gctggtggtg
    18901 gcgctcggac tgcactgcgc gttccaccgc gggcggcgcc gggtcgaggg ggccgaggtc
    18961 tgacgggcgc agggtcagac gaggccctgc atccgccggg cgacccgggc gtgttcgtcc
    19021 aacttctctt cgagtgacga gagttggagt tctccctcgt cgacgaggac gcggccgccg
    19081 acgacagtcg tccaggcccg cgacggggcg cagcgcagcc atgcctcgac cgggtcggtg
    19141 agtgccccgg ccagtgccac cgcgggggtg tcccagacga cgaggtcccc gcaggcgccc
    19201 gggcgcagct gtcccaactc gtccgcgcgg cccaggcagc gggccgagcc gcgggtggcg
    19261 atatccaggg cgtcccgggc ggtcatcgcc gacgggccgc cgcggtagcg acccagcagc
    19321 agggcgctgc gggtctccag ccacagcgag gcgtggtcgg tggaggcgga gccgtcgcag
    19381 ccgatgccga ccggcatgcc cagtccgcgc atctcccgga ccgccgccgt cccgccggcg
    19441 atcagcatgt tggaactggg acagtgcgcc accccgaccc cggcggcggc gagccgggcg
    19501 cgctcctcct tggtggggtg gatgcagtgc gccacccacg tgcggtcggt catccagccg
    19561 accgactcga agtactcgac gggtcggcag ccgtaggtct ccaggcagta ggcgtcctcg
    19621 tccgggtcct cggcgaggtg ggtgtgcagc cggacgtcga gccgctcggc caactcggcg
    19681 gtcgcggtca tcagttcccg ggtcaccgag aacggtgagc agggcgcgag ggcgacttgg
    19741 gtcagcgcgc ccggggccgc atcgtggtag gtctgcacca gtcgctcgct gtccgccagc
    19801 acctcctcgg cggtctgggt gaccgagcgg ggcggcagcc cgccgtcctc ggtcgagcgg
    19861 gtcatcgagc cgcgggtggc gtggaagcgg aaacccacct cctgggcggt gcggatctgg
    19921 gcgtcgatca ggcgcggccg cggatggacg tagtggtggt ccatcgaggt ggtgcagccg
    19981 cccagcagca gttccgcgat gccgacgtag gtggcgaggt gcacggcctc ctcgtcgagg
    20041 gcggcccaca gcgggtagag ggtggtgagc caggtgaaga gggtgccgtt cacggccggg
    20101 gcgtaggcgc gggtgaggtt ctggtacatg tggtgatggg tgttgatcag cccgggggtg
    20161 accaggcgac cggcggcgga cagggtgcgg gtggcgcccg ccggctcgga gccggcgggc
    20221 ccgtacgccg cgacccggcc gtcccggagg gcgatccagc cgccgggtac ctcggtgtca
    20281 ccgtcgatga cgagcagccg ggcgtcccgg acgagcaggt cgcagtggtc cgtcgggtcg
    20341 gcggtgccgt ccggacgggc gtggtggtgg gtgtcggcca tgcgaggact cctgtgatgc
    20401 ggtgtgccga agctccggca cggggcacga tggatgcgcg cgggccctgt accggtgtgg
    20461 tgcgcggcca ccggatcgtc accgccgggc ctgccggcgg gcgggcggtc ctcctccttg
    20521 acgtctcacg tccctgggat ggggacgtaa ctcggcgcgg tgcacacgtc gttggagccc
    20581 tgcccggaat tcgccggacc agtccccggc ccgccccggc ggcgtcaggc cggtcggtgc
    20641 gccggcagcg ggcgccgcag cacgtacccg ccgaccgcca ccgccaccgc gatgacgcac
    20701 ccggcgaa
//
