LOCUS       NZ_CP104098            23348 bp    DNA     linear   CON 08-NOV-2024
DEFINITION  Streptomyces noursei strain IFO14147 chromosome, complete genome.
ACCESSION   NZ_CP104098
VERSION     NZ_CP104098.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces noursei
  ORGANISM  Streptomyces noursei
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9223378)
  AUTHORS   Zeng,X.
  TITLE     Transcriptome and Metabolome Analysis Revealing the Improved
            epsilon-Poly-l-Lysine Production Induced by a Microbial Call from
            Botrytis cinerea
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9223378)
  AUTHORS   Zeng,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2022) College of life science, Huaibei Normal
            University, Dongshan road 100#, Huaibei, Anhui 235000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: PGCGAP v. 1.0.34
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025163575.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 12:09:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,195
            CDSs (total)                      :: 8,101
            Genes (coding)                    :: 7,883
            CDSs (with protein)               :: 7,883
            Genes (RNA)                       :: 94
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 218
            CDSs (without protein)            :: 218
            Pseudo Genes (ambiguous residues) :: 0 of 218
            Pseudo Genes (frameshifted)       :: 93 of 218
            Pseudo Genes (incomplete)         :: 149 of 218
            Pseudo Genes (internal stop)      :: 11 of 218
            Pseudo Genes (multiple problems)  :: 33 of 218
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:04:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4664336
            Orig. end                         :: 4687684
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP104098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23348
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="15"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23348
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23348
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13348](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13348
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(392..407)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.4"
                     /tool="antismash"
     misc_feature    406..420
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.58"
                     /tool="antismash"
     misc_feature    complement(502..516)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.91"
                     /tool="antismash"
     misc_feature    complement(601..614)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            696..968
                     /locus_tag="N1H47_RS20625"
                     /old_locus_tag="N1H47_20625"
     CDS             696..968
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018854168.1"
                     /locus_tag="N1H47_RS20625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20625"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_016572904.1"
                     /transl_table=11
                     /translation="MGSVRWRKSSYSNGMENCVEVADDVSADWGKSSYSGSDGGQCVEI
                     SPSFASAEVIPVRDSKVPQGPTLVFPADGWASFVSAVRHGEFVAF"
     gene            1288..2412
                     /locus_tag="N1H47_RS20630"
                     /old_locus_tag="N1H47_20630"
     CDS             1288..2412
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572903.1"
                     /locus_tag="N1H47_RS20630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20630"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_016572903.1"
                     /sec_met_domain="PCMT (E-value: 8.9e-30, bitscore: 102.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVARLVADGVLTAEWEPVFEGLPRAGFLPDAVWQHHVATGEVEAV
                     NRGRDPQRWREAADSVHPLVTQWDDGGHEGPGRGRVASSSASAPPVVAAMLRDLTVRSG
                     QRVLEIGTGTGWNAALLASRLGAENVTTVEVDTSVAEAARGALQRQGMGAVTVVRGDGF
                     QGYPPRAPYDRIIATCGVHTFPRAWREQCRPGGVIVVPWGTRFTSTEATVALTVAADGR
                     SASGTFKDLVQFMSLRAQRREVPEYADYVTAESRDKAERGATTLTWDETIAGEWDISRF
                     VLGLLVPDCTVILDEPQEGQRPVWLCSLAGDRSWACVLFREDRPESTVYQHGDRRLWDE
                     VEAAYGWWQGQGRPGLGRLGLTVDDDGQHVWVEK"
     gene            complement(2489..2965)
                     /locus_tag="N1H47_RS20635"
                     /old_locus_tag="N1H47_20635"
     CDS             complement(2489..2965)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572902.1"
                     /locus_tag="N1H47_RS20635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20635"
                     /product="VOC family protein"
                     /protein_id="WP_016572902.1"
                     /transl_table=11
                     /translation="MPKITPNLWFDTQGMEAAEFYCSVFPNSKIKNVTHYTEGSPGTPG
                     TVLTVEFELDGREFIALNGGPQFTFDEAISFVVTCADQEEIDHYWAKLSEGGEEGPCGW
                     LKDKYGLSWQVAPDGMADILNDPDRARAARAMQAVMGMKKLDIAAIRAAADGKG"
     misc_feature    complement(2983..2997)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 24.27"
                     /tool="antismash"
     gene            <3225..3745
                     /locus_tag="N1H47_RS20640"
                     /old_locus_tag="N1H47_20640"
                     /pseudo=""
     CDS             <3225..3745
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007824777.1"
                     /locus_tag="N1H47_RS20640"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="N1H47_20640"
                     /product="UTRA domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="LRRRGVQRLAREGWGAGRSVWSVDVGARELVVDQVAVTEEAAPAA
                     VAHVLGMASGSRCACAGVGSSSTASRCCGPRASCPPRWWPVPRSSTRTPDPAAFTRAWP
                     NWAARPCTSGRRSAAGCRPRERWTGCGSVRARR"
     gene            complement(3788..4585)
                     /locus_tag="N1H47_RS20645"
                     /old_locus_tag="N1H47_20645"
     CDS             complement(3788..4585)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536612.1"
                     /locus_tag="N1H47_RS20645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20645"
                     /product="hypothetical protein"
                     /protein_id="WP_020930779.1"
                     /transl_table=11
                     /translation="MRRTTPVAYVATASAAVFCLGGVLTGCGSAAGSGYAAVGAAGPAD
                     PSAPTRPAPPRDGVELTPLDGGGATGPSTPPGSPGSSGPSRPTAPGTTGTTPPGTPGAS
                     DGSGTPPSAPPGSTTGQGSNPPGTKNPAPPGGSPAPGPGGSTTPEPPAPPSPTIPAGPN
                     APSGLVVGKPVLADTDVRWCQRVTIDFLNTGQHPVTAGTVTFGSHVIGALGIDWATLDS
                     TRDLPLPLSPGKPETGTWRVCVDAWRVPLGMHLNTKDVTFKWK"
     gene            complement(4853..5692)
                     /locus_tag="N1H47_RS20650"
                     /old_locus_tag="N1H47_20650"
     CDS             complement(4853..5692)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604265.1"
                     /locus_tag="N1H47_RS20650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20650"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_037635852.1"
                     /transl_table=11
                     /translation="MSVELGSSKVLPAIPAPAPHVHDDVDAINTRSLSRSLFLRLATLD
                     KDSAERAYVRDTLIELNLPLVRYAAARFRSRNEPMEDIVQVGTIGLIKAIDRFDCERGV
                     EFPTFAMPTVVGEIKRFFRDTSWSVRVPRRLQELRLALTKASDELSQKLDRSPTVPELA
                     VCLGVSEEDVVDGLAVGNAYTASSLDSPSPEDDGGEGSLADRLGYEDSALEGVEYRESL
                     KPLLAKLPPRERQIIMLRFFANMTQSQIGEEVGISQMHVSRLLTRTLAQLREGLISD"
     gene            complement(5883..6692)
                     /locus_tag="N1H47_RS20655"
                     /old_locus_tag="N1H47_20655"
     CDS             complement(5883..6692)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014177816.1"
                     /locus_tag="N1H47_RS20655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20655"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_016575579.1"
                     /transl_table=11
                     /translation="MTVTARTAPKAPARESRSADTRALTQVLFAELAGLTPGTPEHSRV
                     RAALIEANLPLVRYAAARFRSRNEPMEDVIQVGTIGLINAIDRFDPERGVQFPTFAMPT
                     VVGEIKRYFRDNVRTVHVPRRLHELWVQVNGATEDLTVLHGRSPTTAEIAERLKIGEDE
                     VLACLEAGRSYHATSLEAAQEGDGLPGLLDRLGYEDPELAGVEHRDLVRHLLVQLPERE
                     QRILLLRYYSNLTQSQISAELGVSQMHVSRLLSRSFARLRSANRIDA"
     misc_feature    complement(6754..6770)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.34"
                     /tool="antismash"
     gene            complement(6957..7250)
                     /locus_tag="N1H47_RS20660"
                     /old_locus_tag="N1H47_20660"
     CDS             complement(6957..7250)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056642.1"
                     /locus_tag="N1H47_RS20660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20660"
                     /product="Dabb family protein"
                     /protein_id="WP_016574700.1"
                     /transl_table=11
                     /translation="MIRHLVLFKLNEGVSRDEERVQAGVRAFAALEKEIPELTFWECAW
                     NITDRPIAYDFAINSAVADTDALKRYIEHPAHQAAAAQWREFATWVIADYEF"
     gene            complement(7307..7471)
                     /locus_tag="N1H47_RS20665"
                     /old_locus_tag="N1H47_20665"
     CDS             complement(7307..7471)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019887721.1"
                     /locus_tag="N1H47_RS20665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20665"
                     /product="hypothetical protein"
                     /protein_id="WP_016574699.1"
                     /transl_table=11
                     /translation="MATAKKVALYLVVIFVLWTIIATPKRAAGLVQIGFEGISTAAQSV
                     GQFMTQLVS"
     misc_feature    7608..7622
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: strong, score: 29.3"
                     /tool="antismash"
     misc_feature    7944..7964
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.93"
                     /tool="antismash"
     misc_feature    7985..8000
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.79"
                     /tool="antismash"
     gene            8098..8883
                     /locus_tag="N1H47_RS20670"
                     /old_locus_tag="N1H47_20670"
     CDS             8098..8883
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536607.1"
                     /locus_tag="N1H47_RS20670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20670"
                     /product="DUF2127 domain-containing protein"
                     /protein_id="WP_016574698.1"
                     /transl_table=11
                     /translation="MKIDWNRRTCARRGHITYLPDETHLQERLHAGTALGTAWRCLRCG
                     DFVLGEPHGSGPACDAPLVPRGKALRDLFILRFLAVERALRGLFVVLAALAVWQFSNSQ
                     DAVRQFFDKNLDVVRPIAVHFHYDLDHSPVVDTIRKTFGYQHSTLLLVAGLLLAYALVE
                     IVEGVGLWWSQRWAEYLAVVATAAFLPLEIYELTEKVSWLKIATLVINILAVLYIAVAK
                     RLFGLRGGRAAFDEERHSASLMEVETSAGVSAPAPAHNG"
     gene            8912..9391
                     /locus_tag="N1H47_RS20675"
                     /old_locus_tag="N1H47_20675"
     CDS             8912..9391
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574697.1"
                     /locus_tag="N1H47_RS20675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20675"
                     /product="hypothetical protein"
                     /protein_id="WP_016574697.1"
                     /transl_table=11
                     /translation="MRPKHTNSAHRQSGSPHAPVRRTWGRRPMVVLALLFGMVAAAAGP
                     AAAAGLSDAAAARPAAVAAPHAPSGARTTPVDAERVEAAAAAPAKWRHSTHSSHHQVTH
                     QASFTSHDKPKKKKMGFFKKLGVFLIVIVVVIIVIVILLIWLIVHFIRKAFRRRG"
     misc_feature    complement(9469..9480)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.61"
                     /tool="antismash"
     misc_feature    complement(9505..9519)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.64"
                     /tool="antismash"
     misc_feature    9631..9646
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            9793..9912
                     /locus_tag="N1H47_RS20680"
                     /old_locus_tag="N1H47_20680"
     CDS             9793..9912
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033434.1"
                     /locus_tag="N1H47_RS20680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20680"
                     /product="azolemycin family RiPP peptide"
                     /protein_id="WP_020930782.1"
                     /transl_table=11
                     /translation="MAEEDDLFEEMAIPESETAFAGHSCLCFVTEYDDTESAE"
     gene            10001..12124
                     /locus_tag="N1H47_RS20685"
                     /old_locus_tag="N1H47_20685"
     CDS             10001..12124
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536604.1"
                     /locus_tag="N1H47_RS20685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20685"
                     /product="YcaO-like family protein"
                     /protein_id="WP_020930783.1"
                     /sec_met_domain="TIGR03604 (E-value: 5.4e-80, bitscore:
                     267.9, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 7.2e-71, bitscore: 238.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METPRPPAPLTLRRDVRLVSRGRHLYVCASTGTLRVPVQLPTDDA
                     DHRTVALDAVPGRVAEGLHARGLAHPGDGRLPHPLYGTGAERGRRPVVVVGDGPLATEA
                     VALLERAGARTAPADTTDQPAAVVLPLDLPEDELRRRTALVLDRGTPLVTYLSTPTRLL
                     LATLSPPRTPCPVCLVRRIRANHTWQPVAGLPLDLLLGAAQSEAWPTTAVAAGAVAHAV
                     LTALAAPEAPTGPPELTELDHATWERTGHALFHTPGCPACASAAVPPKRDGTAAVDVAE
                     SWRLMRGAVDPLTGLVPELRVDEPSGPDGTTYARTAGMTTTTWFSPVAAEARGGAVKSD
                     PVNARVCAVGETMERYAAGVYDPDRLVRATLAELGDAAVDPRSLPLGSDQEYAAQRRYA
                     PFDPAVPIDWVAGTSLTTGRPRYVPACAVYLPYRFPRAHKPWFDPISTGLAAGGSYHHA
                     VLGGLMESVERDATLVFWENRLTLPGLDLTGLPDGPARRIVDRITAEGATVTCKDLTTD
                     LGIPAVAVRFAGGTAERPVVVHAARADLDPHTALLGALEEACLCRTGAGIWLEEGEVPA
                     ADAALSSLSEFCLYYCAPDRQHHLAFWADGPLHPLPAARPAGSLQDDVAEAVRRLAARG
                     HEAIAVDLTPIDVAECGVSVVRTVVPGLCPLTLRSDFHRRGGPRVRQAPVAMGVRATAL
                     TEDQLNPWPLPFL"
     gene            12182..13348
                     /locus_tag="N1H47_RS20690"
                     /old_locus_tag="N1H47_20690"
     CDS             12182..13348
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572558.1"
                     /locus_tag="N1H47_RS20690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20690"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_016572558.1"
                     /sec_met_domain="PF00881 (E-value: 2e-15, bitscore: 56.1,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDTTAHDAPGAPNGAPDHDARPYRRNPDLLLEWADGGGPVLVDC
                     GSWRKFAAKPVLVDLLNHLDRPHTADQLQDRWRESAPGGDVRRLLDRLAAAGILRRCAP
                     PPTDAADAADTEDAAEGAAKDPGAGWTAYERAVHARSGLGPDAAAGRGTPPPARLHHPG
                     VDAVVALPDGADAPSRPLVDVLAARRSVRGYAPDPVPLPLLAALLARAARVRGHLAPRA
                     YQQTQRPAPSGGARHSLEVHLVARAVAGLAPGAYHYDPFAHALHRLAPWTDDLAAFQQR
                     TVTDPALLDHAPPASLCLTAVAARTTWKYEGMALSLIYRDTGCLMQTLSLTATDLGLAS
                     CLTGRMEAPFTAPFLPPSLRAHLSHVGNMALGLPTSPLAAPDVTPLDP"
     misc_feature    complement(13469..13482)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.98"
                     /tool="antismash"
     gene            13553..14329
                     /locus_tag="N1H47_RS20695"
                     /old_locus_tag="N1H47_20695"
     CDS             13553..14329
                     /NRPS_PKS="Domain: PKS_KR (18-168). E-value: 1.6e-09.
                     Score: 29.9. Matches aSDomain:
                     nrpspksdomains_N1H47_RS20695_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572557.1"
                     /locus_tag="N1H47_RS20695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20695"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_016572557.1"
                     /sec_met_domain="adh_short_C2 (E-value: 1.7e-31, bitscore:
                     108.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSETGRGTRELAGKRALVTGGTRGIGAAVVRQLLAAGAEVLTT
                     ARTAPDTVPQGAAFVAADVQTRAGAEALAAAAQETLGGVDVVVHNAGGARPHAGASAIP
                     DEEWQAALDLNFLSSVRLDSLLVPGMRERRSGAIVHVSSAAVRTPVGQFLHYTTAKAAL
                     ENYSRGLSSELAPFGIRVNTVSPGRTATPGGEATREQWARLNAAPGQTNAADAPPLGRD
                     GRPDDIADAVLFLVSDRAGWLTGSNLVVDGGEFPRG"
     CDS_motif       13607..13675
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_N1H47_RS20695_0001"
                     /evalue="6.70E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="N1H47_RS20695"
                     /protein_end="41"
                     /protein_start="18"
                     /score="18.8"
                     /tool="antismash"
                     /translation="LVTGGTRGIGAAVVRQLLAAGAE"
     aSDomain        13607..14056
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_N1H47_RS20695_PKS_KR.1"
                     /evalue="1.60E-09"
                     /label="N1H47_RS20695_PKS_KR.1"
                     /locus_tag="N1H47_RS20695"
                     /protein_end="168"
                     /protein_start="18"
                     /score="29.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LVTGGTRGIGAAVVRQLLAAGAEVLTTARTAPDTVPQGAAFVAAD
                     VQTRAGAEALAAAAQETLGGVDVVVHNAGGARPHAGASAIPDEEWQAALDLNFLSSVRL
                     DSLLVPGMRERRSGAIVHVSSAAVRTPVGQFLHYTTAKAALENYSR"
     misc_feature    14351..14364
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.08"
                     /tool="antismash"
     misc_feature    complement(14351..14365)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.46"
                     /tool="antismash"
     misc_feature    14352..14365
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.81"
                     /tool="antismash"
     misc_feature    14353..14366
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.44"
                     /tool="antismash"
     misc_feature    complement(14354..14367)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.78"
                     /tool="antismash"
     misc_feature    complement(14377..14393)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.72"
                     /tool="antismash"
     gene            14428..15171
                     /locus_tag="N1H47_RS20700"
                     /old_locus_tag="N1H47_20700"
     CDS             14428..15171
                     /NRPS_PKS="Domain: PKS_KR (9-173). E-value: 1.5e-18. Score:
                     59.3. Matches aSDomain:
                     nrpspksdomains_N1H47_RS20700_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028373.1"
                     /locus_tag="N1H47_RS20700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20700"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_016572556.1"
                     /sec_met_domain="adh_short (E-value: 7.1e-34, bitscore:
                     116.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 2.1e-32, bitscore:
                     111.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKYSGKNAVITGGGSGIGLATAKLLVDEGARVVITGRSRTTLDA
                     ALEHLGPHAVAVRGDVAALPDLDALADRVRGEFGTLDALFVNAGIATLTPFASTTEKAY
                     DELFAINVKGAYFSVQKLAPLLNTGAGVVLTTSVANVLGVPETSVYAAGKAALRSMARS
                     LSRELLPRGIRVNAVSPGPVDTGVLEGTLTPEAAEEFKAQQVAGNPMRRFGTPEEIAGA
                     AAFLAFDATYTAGAEFVVDGGATQL"
     CDS_motif       14455..14544
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_N1H47_RS20700_0001"
                     /evalue="1.10E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="N1H47_RS20700"
                     /protein_end="39"
                     /protein_start="9"
                     /score="27.7"
                     /tool="antismash"
                     /translation="VITGGGSGIGLATAKLLVDEGARVVITGRS"
     aSDomain        14455..14946
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_N1H47_RS20700_PKS_KR.1"
                     /evalue="1.50E-18"
                     /label="N1H47_RS20700_PKS_KR.1"
                     /locus_tag="N1H47_RS20700"
                     /protein_end="173"
                     /protein_start="9"
                     /score="59.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VITGGGSGIGLATAKLLVDEGARVVITGRSRTTLDAALEHLGPHA
                     VAVRGDVAALPDLDALADRVRGEFGTLDALFVNAGIATLTPFASTTEKAYDELFAINVK
                     GAYFSVQKLAPLLNTGAGVVLTTSVANVLGVPETSVYAAGKAALRSMARSLSRELLPRG
                     I"
     gene            complement(15179..16066)
                     /locus_tag="N1H47_RS20705"
                     /old_locus_tag="N1H47_20705"
     CDS             complement(15179..16066)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572555.1"
                     /locus_tag="N1H47_RS20705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20705"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_016572555.1"
                     /transl_table=11
                     /translation="MSLRQFEYALAVAEEGSVTAAAERLRVAQPSVSQQIRGLERELGV
                     ELFARTPTGLVPTVVGRAFLRDAEAAVHAARRARATARAGAEELVGELVVTVQMGFGTR
                     QLPGALGALRRRFPRVEVTVFEEPSSAEMDRLCRRGALDLALMAKCERTPANAHHLGDE
                     EFVVVLGAGHPQLAAERVELRELAGEPWVRFDRDSALDGVLLQVLRDNGLTPTTVARVS
                     QTATAVRWAAHGLGATLVPASAVPRGHEHLVRPVFPAVSQPVIAVVRPVAGPAETALLE
                     LLRQETWSEPVAQR"
     misc_feature    16272..16286
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.01"
                     /tool="antismash"
     tRNA            complement(16306..16393)
                     /anticodon=(pos:complement(4680693..4680695),aa:Ser,
                     seq:cga)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="N1H47_RS20710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="N1H47_20710"
                     /product="tRNA-Ser"
     gene            complement(16306..16393)
                     /locus_tag="N1H47_RS20710"
                     /old_locus_tag="N1H47_20710"
     gene            complement(16462..16962)
                     /gene="tadA"
                     /locus_tag="N1H47_RS20715"
                     /old_locus_tag="N1H47_20715"
     CDS             complement(16462..16962)
                     /EC_number="3.5.4.33"
                     /GO_function="GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /gene="tadA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1240: riboflavin biosynthesis protein RibD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010467966.1"
                     /locus_tag="N1H47_RS20715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20715"
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="WP_020930784.1"
                     /transl_table=11
                     /translation="MTVPPSASLPSPTPDPLRDPWTGPMRRALAEAARAPGTGDVPVGA
                     VVLSADGTVLGTGHNEREATGDPTAHAEVLALRAAARTVGQWRLTGCTLLVTLEPCTMC
                     AGAIVLSRVDRVVYGARDAKAGAVGSLWDVVRDRRLNHRPEVVTGVLEADCAALLTAFF
                     RDR"
     gene            complement(17030..17554)
                     /locus_tag="N1H47_RS20720"
                     /old_locus_tag="N1H47_20720"
     CDS             complement(17030..17554)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003974923.1"
                     /locus_tag="N1H47_RS20720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20720"
                     /product="hypothetical protein"
                     /protein_id="WP_016572553.1"
                     /transl_table=11
                     /translation="MYFAALLARTEDGWEASDTELDDVETLTDLADLAREAAADDTVVV
                     LIEQEDAWFGVVRIDGEDDPRVFVSNAALAARSSYGTMLTDELLGRDDDADDLDLLDLD
                     GTEDGEPETEDEDPEGRDADEEPVARGPLGDARLLEDVGVGERELLALDGDALGSIAEA
                     LGCSDLLEAVR"
     gene            17771..18406
                     /gene="upp"
                     /locus_tag="N1H47_RS20725"
                     /old_locus_tag="N1H47_20725"
     CDS             17771..18406
                     /EC_number="2.4.2.9"
                     /GO_function="GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="upp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004943140.1"
                     /locus_tag="N1H47_RS20725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20725"
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="WP_016572552.1"
                     /transl_table=11
                     /translation="MRIHVVDHPLVAHKLTTLRDKRTDSPTFRRLADELVTLLAYEATR
                     DVRTEQVDIETPVTATTGVRLSHPRPMVVPILRAGLGMLDGMVRLLPTAEVGFMGMVRN
                     EETYEAHTYATRMPDDLSGRQVYVVDPMLATGGTLVAAIKELIKRGADDVTAICLLAAP
                     EGVEVMERELAGTPVTVVTAAVDEQLNADRYIVPGLGDAGDRMYGTAG"
     misc_feature    17816..17829
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.05"
                     /tool="antismash"
     gene            complement(18478..19119)
                     /locus_tag="N1H47_RS20730"
                     /old_locus_tag="N1H47_20730"
     CDS             complement(18478..19119)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240524.1"
                     /locus_tag="N1H47_RS20730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20730"
                     /product="LytR C-terminal domain-containing protein"
                     /protein_id="WP_078487174.1"
                     /transl_table=11
                     /translation="MSMLTPPGMGGKYRITGDRYPRMRRPRHRRRIILSIVASACALGL
                     VGWGTLQLIDVFGGRGSTAQAAQDTRPCPDGTGGPTKAAPSAAKPPAPASLTVNVYNAT
                     PRSGLAKRTADELQKRGFKIGKVGNAPAAYDKKVAGTGMLLGPAAATGGALKVLATQLA
                     GAQLKTDDRKGADLDLIIGGAFKELTAPQQAAKALALLSRPAQAPAPAKC"
     misc_feature    complement(19149..19165)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.24"
                     /tool="antismash"
     gene            complement(19265..19564)
                     /locus_tag="N1H47_RS20735"
                     /old_locus_tag="N1H47_20735"
     CDS             complement(19265..19564)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572550.1"
                     /locus_tag="N1H47_RS20735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20735"
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="WP_016572550.1"
                     /transl_table=11
                     /translation="MIFKRIGNGRPYPDHGRESTRQWADVAPRPVRLDQLVTTKQQLDL
                     ETLLAEDSTFYGDLFAHVVKWEGDLYLEDGLHRAVRAALQQRQVLHARVLELDN"
     misc_feature    19536..19552
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.99"
                     /tool="antismash"
     gene            complement(19743..20393)
                     /locus_tag="N1H47_RS20740"
                     /old_locus_tag="N1H47_20740"
     CDS             complement(19743..20393)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572549.1"
                     /locus_tag="N1H47_RS20740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20740"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_016572549.1"
                     /transl_table=11
                     /translation="MPLRPAPSPPTPSGCTGAARRARTLVAAVLAAAAALPLAACQNAG
                     GERDAAGPRTVAAPTPTAGAHPRDRHACTPDMLRFHAGAEPHRDRRMLLTVTNVADRTC
                     TFAAQPYPLLHFGDRLPGPLPPLPYSRPRTPVVLPPDGTAYAEVLTAAAPGGPGGRSAP
                     ASTTEKASQFGIALTARTTPAQVGVDGRAPIRVDPGTAAVTYWQPGPPAPGRW"
     gene            complement(20439..21032)
                     /locus_tag="N1H47_RS20745"
                     /old_locus_tag="N1H47_20745"
     CDS             complement(20439..21032)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N1H47_RS20745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="N1H47_20745"
                     /product="hypothetical protein"
                     /protein_id="WP_020930785.1"
                     /transl_table=11
                     /translation="MSTRDTAPWDATGERPVEDRLRRALAARADAVDVHDLRPAAPPGP
                     RPGRSRPTWLALRTAFRPRRLALPLAAAATAAVVALAAHLATTSDRAPAPPQPAAPPAP
                     STPSPRGATPTPVPSPSAPGHSAEPGRGPLGTAPSSPSRRPTPSTAPPAPTSRPSGRAT
                     SGASGGAEPSRLPTPATSTPSAPPATATASPGVR"
     gene            complement(21029..21703)
                     /locus_tag="N1H47_RS20750"
                     /old_locus_tag="N1H47_20750"
     CDS             complement(21029..21703)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016577449.1"
                     /locus_tag="N1H47_RS20750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="N1H47_20750"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_016577449.1"
                     /transl_table=11
                     /translation="MAHYAPHPAPAGFALPGLRRAAWRRLLRAVRRESPARHSASVHQL
                     PASARQSAHAWDDAPEPHRPTLTELYHAHRLKMVRLAVLLVDDRATAEDVVQDAFAALY
                     KRHGEQLGEVDNALAYLRTAVVNAARSVLRRRRTAREYTPPHEADAPSAEERVVLDEEH
                     REVLAALGALTARRREVLVLRYWGDLTEAQIATTLGISRGAVKSLASRALDALEKILEE
                     RS"
     gene            complement(21729..22274)
                     /locus_tag="N1H47_RS20755"
                     /old_locus_tag="N1H47_20755"
     CDS             complement(21729..22274)
                     /GO_component="GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="N1H47_RS20755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="N1H47_20755"
                     /product="LPXTG cell wall anchor domain-containing protein"
                     /protein_id="WP_124428156.1"
                     /transl_table=11
                     /translation="MRAPPGATVDELEQPTVNPSRTARPSRTRRAAGAGLLAAMALAAV
                     STTGTAYAAPASAHASGPAASASPSPVPTQPPGHGSGPSAEPTQPPSHSSAPSAEPTYP
                     PGHSATPSPVPPGGTATPSPVPSQPGSRPAPGKDTGDGQQLAKTGASSGTTLALGAGAA
                     ALIAVGGGALYVVRRNRA"
     misc_feature    22317..22328
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.11"
                     /tool="antismash"
     misc_feature    complement(22603..22617)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.19"
                     /tool="antismash"
     misc_feature    complement(23248..23262)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.75"
                     /tool="antismash"
ORIGIN
        1 gttgagcgag gcgaacaact cccgtcggag aaaatggtgt gcgcactcga tgagttgttc
       61 gcgacggggg gaacgctggc tgacatcctt gaagtcatca gggctggggc gactcaagcg
      121 tatgtccgga gagctgccga gcaggaatcg aaggcggaac gtattcaggt cttcacgagc
      181 agcaccatcc cggcgctcct gcagacggaa gcctatgccg aagcgtttat ccgaactgag
      241 cgtccgaagg cgccggttgg cgatatcgcc gaggcggtgg gggcccggct cgggcgcaag
      301 cgtgtcttcg acaggcagga tcccccgccg tactgggcaa tcatggacga agcggcgcta
      361 aggcgaccaa tggggagtca gcagttaatg gctgaccagt tggtgcatat cttgaaagtt
      421 gtcgaagctc cgcatgtcac ccttcaggtg atgcccttcg accgtggcga gtactggatg
      481 ctcggaggta gcctgacgct gatcaccaag gctaatgggg cgaccatcgc ctacgttgaa
      541 tcgttcggat cgggcgagct ggtggagtcg acgcgacgag tcgttcaact gacccaacaa
      601 ttcgattcgg tccgccgctt ggcgctttct gaaccagact cattaaacct tgttggaaag
      661 tacctggagg agtaccggtg acgagaagcg gaagtatggg cagcgtccgg tggcgcaagt
      721 ccagttacag caatggaatg gaaaactgcg tcgaggtcgc ggacgacgtc tccgccgact
      781 ggggcaagtc ctcgtacagt ggctctgacg gaggccagtg cgttgagatc tccccgagct
      841 tcgcgtcggc cgaggtgatc ccggtccgcg acagcaaggt gccgcagggg ccgaccctgg
      901 tcttcccggc agacggctgg gcgtccttcg tatctgccgt taggcatggc gagttcgtcg
      961 ccttctgaag tccaactgtc gatcgcggca gtgaaccgcc ctttgtggat gggcaggttg
     1021 acgtgtcggc gtccgcgaag tgcaagcggc actgggcgct tcgtcagtgc cggcttccct
     1081 ccgccatccg tcgcctacta gcgtgcgtcg tctcgtaggt gcgaaaacgg gagagaccat
     1141 aggaaagcgc gacaagcttg atgacggcgg caggcccgac aaacttcccg ggcagccgtg
     1201 gaccccgccc aaggaaccgc cgcagaccga cggcggcgcg cccaagggcg gcgggaaaca
     1261 cggcaagtga gcgggcggtg gcggggaatg gttgcgcggc tggtggcgga cggagtgctg
     1321 accgccgaat gggagcccgt gttcgagggc ctgccccgag ccgggttcct gcccgatgcc
     1381 gtctggcaac accatgtggc gactggagaa gtcgaagccg tcaaccgggg gcgcgatccg
     1441 cagcgatggc gcgaggcggc cgattccgtc catcccctgg tgacgcagtg ggacgacggg
     1501 gggcacgaag gtccgggtag gggccgggtg gcgtcgtcgt cggcgtcggc gccacccgtc
     1561 gttgccgcga tgctgcgcga cctcaccgtg cgttccgggc aacgggtgct ggagatcggc
     1621 accgggacgg gctggaacgc cgctctcctc gcatcccgcc tcggtgccga gaacgtgacc
     1681 acggtggagg tagacacctc cgtggccgaa gcggcccgag gcgccctgca acgacagggg
     1741 atgggggcgg tcacggtcgt ccgcggcgac ggcttccagg ggtacccgcc ccgcgcgccg
     1801 tacgacagga tcatcgccac ctgcggggtg cacaccttcc ctcgtgcctg gcgggagcag
     1861 tgtcgccctg gcggcgtgat cgtggtgccg tggggcaccc gcttcacgtc cacggaagcc
     1921 acggtcgcgc tcacggtcgc ggcggacggc cggagcgcca gcgggacgtt caaggacctg
     1981 gtccagttca tgagtcttcg ggcccagcgt cgtgaagtgc ctgagtacgc ggattacgtg
     2041 accgccgagt cccgggacaa ggcggagcgc ggcgccacga cactcacgtg ggacgagacg
     2101 atcgccggtg aatgggacat cagccggttt gtcctcggcc tgctcgtccc cgactgcact
     2161 gtcatcctcg acgagccgca ggagggccaa cggcccgtgt ggctctgtag cttggccggt
     2221 gaccgctcct gggcgtgcgt actgtttcgg gaggataggc cggaatccac ggtctaccag
     2281 cacggtgacc ggcggctctg ggacgaggtc gaggccgctt acggctggtg gcaggggcag
     2341 ggccgccccg gcctcggccg cctcggtctg accgtcgatg acgacgggca gcacgtgtgg
     2401 gtggagaagt aggtccggct cacccgcgag gtggagagcc cctggaattc gtcagccggg
     2461 ggccgttgcc gtgtagctgc caggcggctc accccttccc gtcggccgcc gccctgatgg
     2521 ccgcgatgtc cagcttcttc atgcccatca cggcctgcat cgcgcgggcc gcacgggccc
     2581 ggtcggggtc gttcaggatg tcggccatcc cgtccggggc gacctgccag gacagcccgt
     2641 acttgtcctt cagccagccg caggggccct cctcgccgcc ctcggagagc ttggcccagt
     2701 agtggtcgat ctcctcctgg tcggcgcagg tgacgacgaa ggagatggcc tcgtcgaagg
     2761 tgaactgcgg cccgccgttg agcgcgatga actcccggcc gtccagttcg aactcgacgg
     2821 tcagcaccgt gccgggcgtg cccgggctgc cctccgtgta gtgcgtgacg ttcttgatct
     2881 tcgagttcgg gaagaccgag cagtagaact cggcggcctc catgccctgg gtgtcgaacc
     2941 agaggttggg ggtgatcttc ggcatgacgc gctcctggtg agggggccgg acggccggct
     3001 gacggtgatc ggttgatcgg cggcccgggg gccgtcctct gtatcgaccg tcgcgcggtg
     3061 ccggactcat cgccattcgg gtacgaattc cgccgacgag gtccccagtc ccgcgaggag
     3121 ggcgcatgaa cgccgaggag cagggtcagc cgcagccgca gtaccgagac cgcgccgagg
     3181 ggtgggacga ggtcgacgca gccctccggg acgccccgcc attgctgcgc cgccgaggcg
     3241 tccagcggct cgcgcgggag gggtggggag cggggcggtc ggtctggtcg gttgacgtcg
     3301 gggcgcggga gctggtcgtc gaccaggtcg ccgtcacgga ggaggcggcg cccgcggccg
     3361 tcgcgcacgt gctcggcatg gcatcgggga gccggtgtgc gtgcgccggc gtcggttcgt
     3421 cctcgacggc aagccggtgc tgtgggccac gagcttcctg cccgccgcgt tggtggccgg
     3481 ttccgcggtc gtcgacgagg acaccggacc cggcggcatt tacgcgcgcc tggccgaact
     3541 gggcagcgcg cccgtgcact tccgggagga ggtccgcagc cggatgccgt ccgagggaga
     3601 ggtggaccgg ctgcggctcg gtgcgggcac gccggtgatc gtcatcgtcc gcaccgcctt
     3661 cgcggacggc gggcgcgcgg tggaggtcaa cgagatggtc ctggactcgg ccgcgtacgt
     3721 cctcgaatac gacgtgcgcg cgtaacggtg gccggccggc cgtcgtctgt catgaaccgc
     3781 cgcccgctca cttccacttg aacgtgacgt ccttggtgtt caggtgcatg ccgagcggta
     3841 cgcgccaggc gtccacgcag acccgccagg tgccggtctc cggttttccg ggggacaggg
     3901 ggagcgggag gtcgcgggtg gagtcgaggg tggcccagtc gatgccgagg gcgccgatga
     3961 cgtggctgcc gaaggtgacg gtgcccgcgg tgaccgggtg ttggccggtg ttgaggaagt
     4021 cgatggtgac ccgctggcac cagcggacgt cggtgtccgc gagcacgggt ttgccgacga
     4081 ccaggccgga cggggcgttg gggccggccg ggatggtggg ggagggtggg gcgggcggct
     4141 cgggggtggt ggaaccgccg ggtccgggtg cgggtgaacc gccgggaggg gcagggttct
     4201 tggtgccggg aggattgctg ccctgacccg tcgttgagcc gggcggggct gagggcgggg
     4261 tgccggagcc gtcggacgcg ccgggtgtgc cgggcggggt ggtgcccgtg gtgcccggtg
     4321 cggtcgggcg ggaagggccg gaagagcccg gggagccggg aggggtggaa gggccggtgg
     4381 cgccgccgcc gtccaggggc gtcagttcga cgccgtcccg tgggggcgcg ggtctcgtgg
     4441 gtgcgctcgg gtcggcgggg cctgccgcgc ccactgcggc gtagccggat ccggccgcgc
     4501 tgccgcagcc ggtgaggacg ccgcccaggc agaacacggc cgccgaggcg gtggcaacgt
     4561 aggcaacagg cgtggtccgt cgcatggtgc ggacacctcc cagcggtagc tgggcacagt
     4621 gttgctgacg aaccatcaga agagaagggt ggcggagcgc agggctgcgc cgcgcgaagg
     4681 gtcggcgcgg ggccgaaggg gtgggggcga aggggtgggg gcgtcacggg agtcacggca
     4741 cgcggccggt ggaggcggag tcgggcgtcg cgcgagggcg cgccgtcgtc ttggttgctg
     4801 tccgccgagc gaccggatcg gcgctcgccg atgcccctcg gcggaccgtg cctcagtccg
     4861 agatcagacc ttcccggagt tgtgccagcg tgcgggtgag cagccgggag acgtgcatct
     4921 gggagatgcc gacctcctcg ccgatctggg actgcgtcat gttggcgaag aaccgcagca
     4981 tgatgatctg gcgctcccgg ggcgggagtt tggccagcag cggcttgagg gactcgcggt
     5041 actccacgcc ctccagcgca ctgtcctcgt agccgaggcg gtccgcaagg gagccctcgc
     5101 cgccgtcgtc ctcgggcgag ggggagtcga gcgaggaggc ggtgtaggcg ttgcccaccg
     5161 ccaggccgtc gacgacgtcc tcctccgaca cccccaggca cacggcgagt tcgggcaccg
     5221 tgggcgagcg gtccagcttc tgggagagct cgtcgctggc cttggtgagg gccaggcgga
     5281 gctcctggag gcgacgcggg acgcgcacgg accacgacgt gtcgcggaag aagcgcttga
     5341 tctcgccgac cacggtcggc atcgcgaacg tcgggaattc caccccgcgt tcgcagtcga
     5401 aacggtcgat ggccttgatc agaccgatgg tgccgacctg gacgatgtcc tccatcggct
     5461 cgttgcggct gcggaagcgc gcggccgcgt aacgcacgag cgggaggttg agttcgatga
     5521 gtgtgtcgcg cacatacgcg cgctcggcgg agtccttgtc gagcgtggcg agccgcagga
     5581 acagggaccg ggagagcgag cgggtgttga tggcgtcgac gtcgtcatgc acgtgtggtg
     5641 ccggcgcggg aatcgcggga agcaccttcg agctgcccag ttctacggac atgccacccc
     5701 cttgaggtcg cggacgggtc gctgcggcgt ccccggccca gggcggaccg aggagttatg
     5761 cctccacctg aataccggag gcagcaccac ggcaaacgcg gttccagcag aatgtcacat
     5821 gtcggcaacg cgctgtagcg tcttgtcgac atatccgtgc aggaacgggt cgcccgtgcc
     5881 ggttaggcgt cgatcctgtt tgcggatcgc agtcgggcga agctccgcga cagtagccgg
     5941 gacacgtgca tctgcgaaac cccgagttcc gcactgatct gggactgcgt cagattgctg
     6001 tagtaacgaa gcaggaggat gcgctgctcg cgctccggga gctggacgag gaggtgccgc
     6061 acgaggtccc ggtgctcgac gccggccagt tcggggtcct cgtagccgag gcggtccagc
     6121 aggccgggca ggccgtcgcc ctcctgggcg gcctccagcg atgtggcgtg gtacgaacgg
     6181 cccgcctcca ggcaggccag cacctcgtcc tcgccgatct tcagccgctc ggcgatctcg
     6241 gcggtggtgg gggagcggcc gtgcagcacc gtgaggtcct cggtggcgcc gttgacctgg
     6301 acccacagct cgtgcaggcg gcgcgggacg tgcacggtgc ggacgttgtc ccggaagtag
     6361 cgcttgatct cgccgacgac ggtgggcatc gcgaaggtgg ggaactgcac gccgcgctcc
     6421 gggtcgaacc ggtcgatggc gttgatcagg ccgatggtgc cgacctggat cacgtcctcc
     6481 atgggttcgt tgcggctgcg gaagcgggcc gcggcgtagc ggaccagcgg gaggttggcc
     6541 tcgatcagtg cggcacggac gcgggagtgc tcgggggtgc cgggtgtcag gcccgccagc
     6601 tccgcgaaga gcacctgcgt cagcgcccgg gtgtccgcgc tacggctctc gcgggccgga
     6661 gccttgggcg cagtacgggc cgtcacggtc acgccaccct tcacagtgca tgtatcgcag
     6721 catgtatcgc gtatcgcatg tatccggcaa aagcggtcat agcatcacaa gacatgtgca
     6781 ctgtgtgcaa gcaccccata acgccgtgtt gaagagagag ttggcgtcac gtgcggggcg
     6841 cgcgcgggtt gcgcgcgacg ggggtgcggt ggggggcccg ggagcatggc gaagcccccc
     6901 gtccgggcgg gcggggggcc gggacgccgg cggcggcgcg gtggcgccgg ccggggtcag
     6961 aactcgtagt cggcgatcac ccaggtggcg aattcgcgcc actgggcggc ggccgcctgg
     7021 tgggccgggt gctcgatgta gcgcttgagg gcgtcggtgt cggcgacggc cgagttgatc
     7081 gcgaagtcgt aggcgatcgg ccggtcggtg atgttccagg cgcactccca gaacgtcagc
     7141 tccgggatct ccttctccag cgcggcgaag gcgcggacgc cggcctgcac gcgctcctcg
     7201 tcgcgcgaga cgccctcgtt gagcttgaac aggaccaggt ggcggatcac gggtggcctc
     7261 cgtgcggcgg gacgatgcgc agccggtccg gcgggccgac tgggacctag ctgaccagct
     7321 gggtcatgaa ctggccgacg ctctgcgcgg cggtcgagat gccttcgaag cctatctgga
     7381 ccagcccggc ggcacgcttg ggggtggcga tgatcgtcca gagcacgaag atgacgacca
     7441 ggtacaacgc cactttcttc gctgtcgcca tcagttccgt ctcccctgcg gcgggaccct
     7501 gtgcccctac ggcgttccgc gtgggccccc tggcccccgt ggccgctccg gttgccggtg
     7561 cggtcgggcg agtgtaacca caggtgttcg accggggcag gcggtgcggg ccgtccggcc
     7621 ctgcccttca cgcgggtctt atggaccaaa ggcccaccaa ggggggtcct tcgcccggct
     7681 gttggggtgg cccgcgggcg gcaggatgga ggcacgggtc acggcgggtc tggcaggaat
     7741 ccgcggggcc ctgggaccag cgccccactg cggggtccgc gtcgcgcgtt ccctgacggt
     7801 gcggcgtgga catcggggcc ggtcctcatc gggggaggcg gatccaaccc cctggcccgc
     7861 ctcccccggc caacgccccg cgccccgcgc gccgggcgcg cgcaccagtc cggaccgtcg
     7921 tcccggcaac ctcaggaccg ttcttctcgt ccctctgtcc gtaaggcatc cccgtacgcc
     7981 ggcgatttgc gcatgtacgc gacaatcacc cggcacggag cgcggacccg cgccgcggcc
     8041 gaccgccgcg gtgcgacggc ccgcgcggga cgacgagagg aacacggggc tccaacggtg
     8101 aagatcgact ggaaccggcg cacctgtgcg cggcgcggac acatcaccta cctcccggac
     8161 gagacgcacc tccaagagag actgcacgcc ggcaccgccc tgggcacggc ctggcggtgc
     8221 ctgcgctgcg gggacttcgt gctgggcgag ccgcacggct ccgggccggc ctgcgacgcc
     8281 ccgctggtgc cgcgcgggaa ggcgctgcgg gacctgttca tcctgcggtt cctggccgtc
     8341 gagcgggcgc tgcgcgggct gttcgtcgtg ctggcggcgc tcgccgtctg gcagttcagc
     8401 aacagccagg acgcggtacg ccagttcttc gacaagaacc tggacgtggt ccgtccgatc
     8461 gccgtgcact tccactacga cctggaccac tccccggtcg tcgacaccat ccggaagacc
     8521 ttcggctacc agcactccac cctgctgctg gtggccgggc tcctgctggc gtacgccctg
     8581 gtggagatcg tcgagggcgt gggcctgtgg tggtcccagc gctgggcgga gtacctggcg
     8641 gtggtggcga ccgcggcgtt cctgcccctg gagatctacg agctgaccga gaaggtcagc
     8701 tggctcaaga tcgccaccct ggtcatcaac atcctcgcgg tgctctacat cgcggtcgcc
     8761 aagcggctgt tcggcctgcg gggcggtcgc gcggccttcg acgaggagcg gcacagcgcc
     8821 tccttgatgg aggtcgagac gtccgccggg gtgtccgcgc ccgcgcccgc ccataatggc
     8881 tgaacgcacc gtacgagggg gaaagcaacc catgcgaccc aagcacacga actccgcgca
     8941 ccggcagtcc ggttcgccgc acgcacccgt ccgccggacc tgggggcgcc gcccgatggt
     9001 ggtgctggcg ctgctgttcg gcatggtggc cgccgctgcc ggccccgcgg ccgccgccgg
     9061 actgtccgac gccgccgcgg cccgcccggc cgccgtggcc gccccgcacg ctccgtcggg
     9121 cgcccggacg acccccgtcg acgccgagcg cgtcgaggcg gccgccgcgg cccccgcgaa
     9181 gtggcggcac agcacgcaca gcagccacca ccaggtgacg caccaggcgt ccttcacgtc
     9241 ccacgacaag ccgaagaaaa agaagatggg cttcttcaag aagctcggcg tcttcctgat
     9301 cgtgatcgtc gtggtcatca tcgtcatcgt gatcctgttg atctggctga tcgtgcactt
     9361 catccggaag gctttccgcc gccggggctg acggatcacg tcaattcctt ctgcgccgtc
     9421 cgcgcactgc ggggcggtcg gagtccgcaa cggactccga ccgcccccgt tttcgttttc
     9481 cgtgcgattt tcccggggat ttctgagtga ctgaaaagag ggtgtcgccg gccggcggcc
     9541 ggttcgcgcg cttgcgccgc cggaggtctc cgtgagtggc cgcgccgtcg gaagaagtcc
     9601 cagctcaggg gcgtatgtaa agcgcaaaga aatgcgtcgc actatcgtgc taatggggaa
     9661 tcgagtcatt tcatcggttt ttcttgacga ggattacccg ggtccgcagc aatagttgtc
     9721 gagcgctcac ccggagtgtt ggcgggtgtg actcgtgggg taattgagaa atccacggaa
     9781 aggggaatca ccatggccga ggaagacgac ctgttcgagg agatggccat tccggagtcg
     9841 gagacggcct tcgccggcca cagctgtctt tgtttcgtca ccgaatacga cgacacggag
     9901 tcggcggagt aacggcgaga cgtgcctccc ggccggcgga agaaccggcc gggaggcact
     9961 tctcgcgccc ccaccccacg gctcccgaag gcggacagca ttggaaaccc cccggccccc
    10021 cgccccgctc accctccgcc gcgacgtccg gctcgtcagc cgcggccggc acctctacgt
    10081 ctgcgccagc accggcaccc tgcgggtccc cgtccagctg ccgaccgacg acgcggacca
    10141 ccggacggtc gccctcgacg cggtgcccgg gcgggtggcc gaggggctgc acgcccgcgg
    10201 cctggcccac cccggggacg gccgactgcc gcacccgctc tacgggaccg gcgccgaacg
    10261 cgggcgccgg ccggtcgtgg tcgtgggaga cggcccgttg gccaccgagg cggtcgccct
    10321 cctcgaaagg gccggggcac ggaccgcacc ggccgacacc accgaccaac ccgccgcggt
    10381 ggtcctcccg ttggacctgc ccgaagacga actccgccgc cgcaccgccc tggtgctgga
    10441 ccgcgggaca ccgctcgtga cgtacctcag cacccccacc cggctgctgc tcgccaccct
    10501 cagccccccg cgcacgccct gcccggtctg cctcgtgcgg cggatccggg ccaaccacac
    10561 ctggcagccg gtggccggac tgccgctgga cctgctgctg ggcgcggcac agagcgaggc
    10621 gtggccgacc accgccgtcg cggccggcgc ggtggcccac gcggtgctca ccgccctcgc
    10681 cgcccccgag gcacccaccg ggcccccgga gctgaccgaa ctcgaccacg ccacctggga
    10741 gcgcaccggg cacgccctgt tccacacccc cggctgcccc gcgtgcgcga gcgccgccgt
    10801 gccccccaaa cgggacggga cggccgccgt ggacgtcgcg gagagctggc ggctgatgcg
    10861 cggcgcggtc gacccgctga ccgggctggt gcccgaactc cgggtggacg agccgagcgg
    10921 ccccgacggc accacctatg cgcgcaccgc cggcatgacc accaccacgt ggttctcccc
    10981 ggtggccgcc gaagcccgcg gcggcgcggt caagagcgac ccggtcaacg cccgggtctg
    11041 cgcggtgggc gagaccatgg agcggtacgc ggccggggtg tacgaccccg accggctggt
    11101 ccgcgccacc ctcgcggaac tcggcgacgc cgcggtcgac ccgcgcagcc tgccgctggg
    11161 ctccgaccag gagtacgccg cccagcgccg ctacgccccc ttcgaccccg ccgtgccgat
    11221 cgactgggtg gcggggacgt ccctgaccac cggccgcccg cggtacgtcc cggcctgcgc
    11281 cgtctacctg ccctaccgct tcccgcgcgc ccacaagccg tggttcgacc cgatctccac
    11341 cgggctcgcc gccggcggct cgtaccacca cgccgtcctc ggtggcctga tggagagcgt
    11401 cgaacgcgac gccaccctgg tcttctggga gaaccggctg accctgcccg gcctcgacct
    11461 gaccggcctg cccgacgggc ccgcccggcg catcgtggac cggatcaccg ccgagggcgc
    11521 gacggtcacc tgcaaggacc tcaccaccga cctgggcatc ccggccgtcg cggtgcggtt
    11581 cgccgggggc accgccgagc ggccggtcgt ggtgcacgcc gcgcgcgccg acctcgaccc
    11641 gcacaccgcg ctgctgggcg cgttggagga ggcgtgcctg tgccggaccg gcgccggcat
    11701 ctggctcgaa gagggcgaag tgccggcggc cgacgccgcg ttgagcagcc tgagcgagtt
    11761 ctgcctctac tactgcgcgc ccgaccgcca gcaccacctg gccttctggg cggacgggcc
    11821 gctgcacccg ctgcccgcgg cccggccggc cggcagcctc caggacgacg tcgccgaggc
    11881 cgtccgccgg ctcgccgcgc gcggccacga ggcgatcgcc gtcgacctga cccccatcga
    11941 cgtcgccgaa tgcggcgtca gcgtggtccg cacggtggtc ccgggcctgt gcccgctcac
    12001 cctgcgcagc gacttccacc ggcgcggcgg cccccgcgtc cgccaggccc cggtcgcgat
    12061 gggcgtgcgc gccaccgcgc tgacggagga ccaactcaac ccctggccgc tgccgttcct
    12121 gtgacacccg ccgacctccc ccaccgaccg ccgacgaccc gccggaggac cggaccgccg
    12181 catggacgac accacggccc acgacgcacc gggcgccccg aacggcgccc ccgaccacga
    12241 cgcccgcccc taccgccgca accccgacct gctgctggag tgggcggacg gcggcggccc
    12301 ggtcctcgtc gactgcggca gctggcggaa gttcgccgcc aagcccgtcc tcgtcgacct
    12361 gctcaaccac ctcgaccgcc cgcacaccgc cgaccaactc caggaccgct ggcgggagtc
    12421 cgccccgggc ggcgacgtcc gcaggctgct ggaccggctc gccgcagccg gcatcctccg
    12481 ccgctgcgcc ccgcccccga cggacgccgc agacgccgca gacactgagg acgccgccga
    12541 gggcgccgcg aaggaccccg gcgccggttg gaccgcgtac gagcgcgccg tgcacgcccg
    12601 ctcgggcctc ggcccggacg ccgcggccgg ccgcggcacc ccgccgccgg cccgcctcca
    12661 ccaccccggc gtcgacgcgg tggtcgccct tcccgacggc gccgacgcgc ccagccgtcc
    12721 gctggtcgac gtcctggccg cgcggcgcag cgtccgcggc tacgcccccg accccgtgcc
    12781 gctgccgctc ctcgccgctc tgctggcccg cgccgcgcgg gtccgcgggc acctggcgcc
    12841 gcgggcctac cagcagaccc agcgcccggc gccgtccggc ggcgcccgcc acagcctgga
    12901 ggtccacctg gtggcccggg cggtcgccgg actggccccc ggcgcctacc actacgaccc
    12961 gttcgcccat gccctgcacc ggctcgcccc ctggaccgac gacctggccg ccttccagca
    13021 gcgcaccgtc accgaccccg cactgctgga ccacgcgccc ccggccagcc tctgcctgac
    13081 cgccgtggcg gcgcgcacca cctggaagta cgaggggatg gccctcagcc tgatctaccg
    13141 cgacaccggc tgcctgatgc agaccctctc gctgaccgcc accgacctgg gcctggcctc
    13201 ctgcctcacc ggccgcatgg aggccccgtt caccgccccc ttcctgcccc cgtccctgcg
    13261 cgcccacctc agccacgtcg gcaacatggc cctcggcctc cccacgagcc ccctggcggc
    13321 ccccgacgtc acccccctcg atccctgacg cacagtcagt tcccgggtgc cataggaatc
    13381 ccctatggca cccgctggaa tttgctcttt gcctcgtgtt cttttccgga tctaccgtga
    13441 aacggctcga cgaggtgcgc agcgcgactt ctctcgaaga atcgcgcccg gcgcacgccg
    13501 atttctcctt tccgtcgagc ggatccgcac gcgagcgaaa aggaacggtg gcatgaccac
    13561 gagcgaaacc ggacggggaa cgcgcgaact cgcaggaaag cgggcgctgg tcacgggcgg
    13621 cacccgcggc atcggcgcgg ccgtggtgcg ccaactcctg gccgcgggcg ccgaggtgct
    13681 cacgaccgcc agaacggcgc cggacaccgt gccgcaggga gccgccttcg tggcggccga
    13741 cgtgcagacg cgggccggcg cggaggcgct cgccgccgcc gcgcaggaga cgctcggcgg
    13801 ggtggacgtc gtcgtccaca acgcgggcgg ggcgcgcccg cacgcgggcg cctcggccat
    13861 ccccgacgag gagtggcagg cggcgctgga cctgaacttc ctgtcgtcgg tgcggctgga
    13921 ctcgctgctg gtgccgggga tgcgggaacg gcgttcgggg gcgatcgtgc acgtctcctc
    13981 ggccgcggtc cgcaccccgg tgggccagtt cctgcactac acgacggcga aggcggcgct
    14041 ggagaactac agccggggcc tgtcctcgga gctggccccg ttcggaatcc gggtcaacac
    14101 cgtgtccccc ggccggaccg ccacccccgg cggcgaggcg acgcgggagc agtgggcgcg
    14161 cctgaacgcg gcgccgggcc agaccaacgc cgcggacgcc ccgccgttgg ggcgcgacgg
    14221 ccggcccgac gacatcgccg acgcggtgct gttcctcgtc tccgaccggg cgggctggct
    14281 gaccgggagc aacctcgtcg tggacggcgg cgaattcccc cggggatgac accggcggaa
    14341 ttccggaacg ccgttttaga aaaaaggaat gcacgggtgc gagttgatcg cagcccgcgc
    14401 tcacgagaaa gcagaagaaa tccagtcatg ggcaagtaca gcggcaagaa cgcagtgatc
    14461 acgggcggcg gcagcggcat agggctcgcg acggcgaagc tgctcgtgga cgagggggcc
    14521 cgcgtggtga tcaccggtcg ctcccggacc acgctcgacg cggcgctgga gcacctcggc
    14581 ccgcacgcgg tggccgtccg gggcgacgtg gccgcgctcc cggacctgga cgcgctggcc
    14641 gaccgggtgc ggggcgaatt cggcacactc gacgccctgt tcgtcaacgc tggcatcgcc
    14701 accctcacgc ccttcgcctc gacgacggag aaggcgtacg acgaactgtt cgcgatcaac
    14761 gtcaagggcg cctacttcag cgtgcagaag ctcgccccgc tgctgaacac gggtgccggc
    14821 gtcgtcctca ccacctcggt cgcgaacgtc ctcggcgtgc cggagaccag cgtctacgcg
    14881 gccggcaagg cggccctgcg ctcgatggcc cgcagcctct cccgcgaact gctgccgcgc
    14941 gggatccgcg tcaacgcggt cagccccggc cccgtcgaca ccggggtcct ggagggcacg
    15001 ctgaccccgg aggccgccga ggagttcaag gcgcagcagg tcgcgggcaa tcccatgcgg
    15061 cgcttcggca cccccgagga gatcgccggg gcggccgcgt tcctcgcctt cgacgccacg
    15121 tacaccgccg gcgccgaatt cgtcgtggac ggcggcgcca cccagctctg agcccgtcct
    15181 accgttgtgc cacgggctcg gaccaggtct cctgacgcag gagttcgagc agggcggtct
    15241 ccgccgggcc cgcgacgggc cggaccacgg cgatcacggg ctgggacacc gccgggaaca
    15301 ccggacgcac gaggtgctcg tgcccgcggg gcaccgcgga ggccgggacg agcgtcgccc
    15361 ccagcccgtg ggcggcccag cgcacggccg tcgccgtctg ggacacgcgg gcgaccgtgg
    15421 tcggggtcag cccgttgtcc cgcagcacct gcagcagcac gccgtcgagg gcgctgtcac
    15481 ggtcgaaccg cacccacggc tcgcccgcca gctcccgcag ctcgacccgc tccgcggcga
    15541 gctgcgggtg cccggcgccc agcaccacca cgaactcctc gtcgccgagg tggtgggcgt
    15601 tggcgggagt ccgctcgcac ttcgccatca gggcgaggtc cagcgcgccc cggcggcaca
    15661 gccgatccat ctcggcggag ctcggctcct cgaagacggt gacctccacc cgcgggaagc
    15721 ggcgacgcag cgcgcccagc gcccccggca gctgccgcgt gccgaagccc atctgcacgg
    15781 tgaccaccag ctcgcccacc agctcctcgg caccggcccg cgccgtcgcc cgcgcccgcc
    15841 gcgccgcgtg caccgcggcc tccgcgtccc gcaggaacgc gcggccgacc acggtcggca
    15901 ccagccccgt cggcgtccgc gcgaacagct ccacaccgag ctcccgctcc aggccgcgga
    15961 tctgctggga caccgagggc tgggcgacgc gcagccgctc cgccgccgcg gtcaccgaac
    16021 cctcctcggc aacggccagg gcgtactcga actgacgaag gctcatcgga ccccgtcccc
    16081 tccccgcggg gaccgcggcc cccgtcgtcc tcgctgtcac agcgggcaac tcggttccgc
    16141 cggcggagat tcccgccgcg agcggcaact ccgttgaccg tcgaagaaga tgaggggcgg
    16201 gacggctgcc gcgaggacgc ctcaacgccc cagcaccgat caccacgcgg ccctcacgca
    16261 caacaccccc ctgatctgcg tttccacagt tcaggggggt gttactggcg gtagcggagg
    16321 gatttgaacc ctcggtgact tgcgccacac tcgctttcga ggcgagctcc ttcggccgct
    16381 cggacacgct accgagagag agcttagccc aaagggcccc gtgcgccgaa atcggattgc
    16441 ggtcagtggg gcgcgcggcg gtcagcggtc gcggaagaag gcggtcagga gggccgcgca
    16501 gtccgcttcc aggacaccgg tgacgacctc gggacggtgg ttgagccggc ggtcgcggac
    16561 cacgtcccag agggagccga ccgcgccggc cttggcgtcc cgggcgccgt agacgacccg
    16621 gtcgacgcgg gagagcacga tcgcgccggc gcacatcgtg cacggttcga gggtgacgag
    16681 gagcgtgcag ccggtcagcc gccactgtcc gacggtccgg gcggcggcgc gcagggcgag
    16741 gacctcggcg tgtgcggtgg ggtcgccggt ggcctcgcgt tcgttgtggc cggtgcccaa
    16801 caccgtgccg tcggcggaca gcacgacggc gcccaccggg acgtctccgg tcccgggggc
    16861 gcgggcggcc tccgccagcg cccggcgcat cggcccggtc caggggtcgc gcagcgggtc
    16921 gggtgtgggg gaggggaggg aggcggacgg agggacggtc atgtccccag tgtcggggac
    16981 ggggtggtgc ggccggtgcc gggcccggcg gtgcgagggc ccggcgggtt cagcggacgg
    17041 cttccaggag gtcggagcag cccagggcct cggcgatcga cccgagggcg tcgccgtcga
    17101 gggccaacag ctcccgttcg cctacgccta cgtcctccag gagccgggcg tcgccgagcg
    17161 ggccgcgggc cacgggttcc tcgtcggcgt cccggccctc tgggtcctcg tcctccgttt
    17221 ccggttcgcc gtcctcggtg ccgtccaggt cgagcaggtc gaggtcgtcc gcgtcgtcgt
    17281 cgcggccgag cagctcgtcc gtcagcatgg tgccgtacga gctcctggcc gccagcgcgg
    17341 cgttggagac gaagaccctc gggtcgtcct cgccgtcgat ccggacgacg ccgaaccagg
    17401 cgtcctcctg ctcgatgagg accactaccg tgtcgtcggc ggctgcttct cgggccaggt
    17461 cggccagatc ggtcagcgtt tccacatcgt cgagctctgt gtcgctcgct tcccacccgt
    17521 cttcggtgcg cgcgagcagt gcggcgaagt acaccgtgac tctcccactg gtagaggcgt
    17581 gccgggccgg gcggggcggc gctgcacgcc gctgcttccc gccccttcgg aatcgtggca
    17641 gaaacatccc gtccgcgcgg cgtcttcgac gctgcgtcgt gcggacgttg tgagagatgt
    17701 cgctcacgtg ccggagcgcg ggcggcatat gacgggcgcc ggggccttgc ggctcggtta
    17761 gtgtcgaggt atgcggatcc acgtcgtcga ccacccgctg gtggcgcaca aactcaccac
    17821 tctgcgcgac aagcgcaccg actccccgac tttccggcgg ctcgccgacg agctggtcac
    17881 cctgctcgcc tacgaggcca cccgtgatgt gcgcaccgag caggtcgaca tcgagacgcc
    17941 ggtgacggcg accaccggcg tgcggctgtc gcacccccgc cccatggtcg tgccgatcct
    18001 gcgggccggg ctgggcatgc tggacggcat ggtccggctg ctgcccaccg ccgaggtcgg
    18061 cttcatgggc atggtgcgca acgaggagac ctacgaggcg cacacctacg cgacgcggat
    18121 gcccgacgac ctgtcggggc ggcaggtgta cgtcgtcgac ccgatgctgg ccaccggcgg
    18181 cacgctggtc gcggcgatca aggagctgat caagcgcggg gcggacgacg tcaccgcgat
    18241 ctgcctgctc gccgcgcccg agggcgtcga ggtcatggag cgcgagctgg ccggcacgcc
    18301 ggtgacggtg gtcacggccg ccgtcgacga gcagctcaac gcggaccgct acatcgtgcc
    18361 gggcctgggc gacgcgggcg accgcatgta cggcacggcg ggctgagccc gtccttcgcg
    18421 gctgagccgc cggtagtcgc gggccccgca ccacgagtgg tgcggggccc gcggcgttca
    18481 gcacttcgcg ggggccggtg cctgggccgg gcgggacagc agggccaggg ccttggcggc
    18541 ctgctgcggg gcggtgagct ccttgaaggc gccgccgatg atcaggtcga ggtcggcgcc
    18601 cttgcggtcg tcggtcttca gctgggcgcc ggcgagctgg gtggccagca ccttcagcgc
    18661 gccgccggtg gccgccgcgg ggccgagcag catgccggtg ccggccacct tcttgtcgta
    18721 ggcggccggg gcgttgccca ccttgccgat cttgaagccg cgcttttgga gttcgtcggc
    18781 ggtgcgcttg gcgagaccgg agcgcggggt ggcgttgtag acgttgacgg tcagggacgc
    18841 cggggcgggc ggtttggcgg ccgacggggc ggccttggtg ggaccgccgg tgccgtccgg
    18901 gcacggtctg gtgtcctgcg cggcctgggc cgtgctgccc cggccgccga agacgtcgat
    18961 gagctgcaga gttccccagc cgaccagccc gagggcgcag gcgctggcga cgatgctgag
    19021 gatgatgcgg cgacggtggc gggggcggcg catccgcggg tacctgtcgc ccgtgatgcg
    19081 gtacttaccg cccattcccg gaggcgtcag catgctcatg gccgcagcgt agtcccgggc
    19141 gtgtgccgtg cctactagat gatcagtgcg ttgtgtgagg gaaacccgag tgggccaatt
    19201 cgactggcgc cgcggcgggt tcccgtgctg acgcccgaac ggcccagcgg gcgccgtccg
    19261 gccgtcagtt gtcgagttcg aggacgcggg cgtgcagcac ctggcgctgc tggagggccg
    19321 cgcggaccgc gcggtgcagg ccgtcctcca ggtagaggtc gccctcccac ttcacgacgt
    19381 gggcgaagag gtcgccgtag aacgtggagt cctcggcgag cagcgtttcg aggtcgagct
    19441 gctgcttggt ggtcaccaac tggtcgaggc gtaccgggcg cggggcgacg tccgcccact
    19501 ggcgggtgct ctcccggccg tggtcggggt acggccgccc atttccgatg cgcttgaaga
    19561 tcacacggaa agcctaccgg gccggaggca ccgggcgcag ccaggagggg gcggcgcaaa
    19621 ggagatcaat cacggcaaaa ttggatcttt ggtgggtgat gagctggctg atacggcacg
    19681 aacgggctat cgctcgctcg tccgctcgcg acggccggca gccgccccgg aacatggccg
    19741 gatcaccacc gtcccggggc cggtgggccc ggctgccagt aggtgaccgc ggcggtgccc
    19801 gggtccaccc ggatcggggc gcgaccgtcc acgccgacct gtgcgggggt ggtgcgggcg
    19861 gtcagggcga tgccgaattg ggacgccttt tcggtcgtgc tggccggggc gctgcggccg
    19921 cccggtccgc cgggcgcggc ggcggtgagc acttcggcgt aggcggtgcc gtcgggcggg
    19981 aggacgaccg gggtgcgcgg tctgctgtac ggcaggggcg ggagcgggcc ggggagccgg
    20041 tcgccgaagt gcagcagggg gtagggctgc gcggcgaagg tgcaggtgcg gtccgcgacg
    20101 ttggtgacgg tcagcagcat gcggcggtcc cggtgcggct ccgcgccggc gtggaaccgc
    20161 agcatgtcgg gcgtgcaggc gtgccggtcg cgggggtgcg ctccggccgt gggcgtcggg
    20221 gcggcgacgg tgcgcgggcc ggcggcgtcc cgttcgccgc cggcgttctg gcaggcggcg
    20281 agcgggaggg cggccgcggc ggccaggacg gcggcgacga gggttcgggc gcggcgggcg
    20341 gcgccggtgc acccggacgg ggtcgggggc gaaggtgcgg gccggagggg catgggcacg
    20401 attctcgggg aaggggggcc gaagcggaca gggaccggtc agcgaacgcc gggcgacgcc
    20461 gtggcggtgg ccgggggcgc ggacggcgtg gacgtggcgg gcgtggggag gcggctgggt
    20521 tccgcgccgc cgctggcgcc gctggtggcg cggccggacg gccgactggt cggggcgggc
    20581 ggggcggtgc tgggcgtcgg acgcctggag gggctgctcg gggcggtgcc gagggggccg
    20641 cggccgggtt cggcggagtg gcccggggcg gacggggacg ggacgggggt cggggtggcg
    20701 ccgcgcgggg acggcgtgga cggggccggc ggggccgccg gctgtggagg ggccggggcg
    20761 cggtcggagg tggtggcgag gtgcgcggcg agggcgacca cggcggcggt cgccgcggcg
    20821 gccagcggca gcgccaggcg gcgcggccgg aaggcggtgc gcagggccag ccaggtcggg
    20881 cggctgcggc ccgggcgcgg gccggggggc gccgccgggc gcaggtcgtg gacgtcgacg
    20941 gcgtcggctc gggccgcgag ggcgcggcgc agccggtcct cgacggggcg ttcgcccgtg
    21001 gcgtcccagg gggcggtgtc gcgggtgctc aagaccgttc ctccaggatc ttctccaggg
    21061 cgtccagggc gcggctggcc agggacttca ccgcgccgcg gctgatgccg agggtcgtgg
    21121 cgatctgtgc ttcggtgagg tcgccccagt agcgcaggac cagcacctcg cggcggcggg
    21181 cggtgagggc gccgagcgcg gcgaggacct cgcggtgctc ctcgtcgagc accacccgtt
    21241 cctcggcgga cggcgcgtcg gcctcgtgcg gcggggtgta ctcgcgggcg gtgcggcgcc
    21301 ggcgcagcac cgagcgggcg gcgttgacca ccgcggtccg caggtaggcg agggcgttgt
    21361 cgacctcgcc gagctgttcg ccgtggcgct tgtagagggc ggcgaaggcg tcctggacga
    21421 cgtcctcggc ggtggcgcgg tcgtcgacga ggaggaccgc cagccggacc atcttcagcc
    21481 ggtgggcgtg gtacagctcg gtgagggtgg gacggtgcgg ctccggggcg tcgtcccagg
    21541 cgtgggccga ctgccgtgcg gaagcgggga gttggtggac ggatgcggag tggcgggccg
    21601 gcgactcgcg gcggacggcg cgcagcaggc ggcgccaggc ggcgcgccgg agccccggca
    21661 gggcgaatcc tgccggggcc gggtgcggtg cgtagtgggc catcgttccc tcgggcgtac
    21721 ccggtcggtc aggcgcggtt ccggcgcacg acgtagagcg cgccgccgcc caccgcgatc
    21781 agggcggccg cgccggcgcc cagggcgagg gtggtgccgg aggaggcacc ggtcttggcg
    21841 agctgctggc cgtcaccggt gtccttgccg ggggccggcc ggctgccggg ctggctgggg
    21901 accggcgagg gggtggcggt gccaccgggc ggcaccgggg acggggtggc gctgtggccc
    21961 ggggggtagg tgggttcggc gctcggggcg ctgctgtggc tgggcggctg ggtgggttcg
    22021 gcgctcgggc cgctgccgtg gccgggcggc tgggtgggga cgggcgacgg gctggcgctg
    22081 gcggccgggc ccgaggcgtg tgcggaggcg ggggcggcgt acgcggtgcc ggtcgtcgag
    22141 acggcggcga gcgccatagc ggccaggagg ccggcaccgg ccgcacggcg cgtgcgggag
    22201 ggacgggcgg tacgggacgg gttcacggtc ggctgctcca gttcgtcgac ggtggcgccc
    22261 gggggcgccc tcacccgaga cgacgtgcgg ccgggggcgg ggttgccgcc cgcgccgaaa
    22321 aacttttcgc gggccggcac cgcgttcgtg accgtatccc gtgacggccg gccgccggcc
    22381 ggtgcgccgg ggtcggagtc ggccccggct agcccctcgc cgcggtggcc accggcgcgt
    22441 cggcgtggtc gtggtcgtgg tcgtgtgcgc aggcgtcggt ggggccgtgc acggcccagg
    22501 ccgggaacgg gtcgtcggcc gcggtgggga cgggctcgtc gggggcgagg aggcaggcgg
    22561 tcagggcggc gtgcaggggc gccgggcgca ggtcggtgcc gatgaagacg agttcctggc
    22621 cggacgggtc gagcggttcg gcggggccgg tggcgtcgtc ggcgccgtcg gtgtcgtcgg
    22681 cgtgcgtccc ggccggctcg aagcgggcga ccgcgcccgc ctgggaccac aggccggtga
    22741 cgccgggccg ggtggcgagc cggaagaatc ccttggagcg caggacgtcg ccgtaggcgc
    22801 cgctgtccat gccggtggtg acgaactgcc agaggcggcc cgggtggaag gggcgctcgg
    22861 cccggaagac ggtgctggag atgccgtact cctcggtctc ggggacgtgg tcgccgttga
    22921 gttcgcgcac ccagccgggg gcctgttggg cgcgttcgag gtcgaagcgg ccggtgtcca
    22981 ggacctcggc cagcgggacc cggccgtgcc gggcggggac gatccgggcg gccgggttga
    23041 ggcgggcgag ggcggccgca aggcggtccg cggcggccgc cccgaccagg tccgtcttgt
    23101 tgaggacgag gacgtcggcg aactcgatct ggtctatcag caggtcgctg accgtgcgct
    23161 cgtcgtcctc gtacggggcc aggccgcgct ccaccagggc gtcgccgccg gcgagttcgg
    23221 gcaggaacgc ggcggcgtcg acgacggtga ccatggtgtc caggcgcgcc aggtcgccca
    23281 gggtggcgcc gtcgtcgcgc gggacggcga aggtcgcggc gaccggcatc ggctcggaga
    23341 tcccgctg
//
