LOCUS       NZ_CP103352            21612 bp    DNA     circular CON 06-NOV-2024
DEFINITION  Bacillus subtilis strain SRCM117508 chromosome, complete genome.
ACCESSION   NZ_CP103352
VERSION     NZ_CP103352.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus.
REFERENCE   1  (bases 1 to 4125816)
  AUTHORS   Yang,H.-G., Kim,J.-W., Ha,G.-S., Yang,H.-J. and Jeong,D.-Y.
  TITLE     Complete genome sequence of Bacillus subtilis SRCM117508 isolated
            from Cheonggukjang
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4125816)
  AUTHORS   Yang,H.-G., Kim,J.-W., Ha,G.-S., Yang,H.-J. and Jeong,D.-Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2022) Functionality Evaluation Team, Microbial
            Institute for Fermentation Industry, Minsokmaeul-gil 61-27, Sunchang
            56048, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 179.3x
            Sequencing Technology             :: PacBio Sequel; Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024800645.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 10:34:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,390
            CDSs (total)                      :: 4,269
            Genes (coding)                    :: 4,029
            CDSs (with protein)               :: 4,029
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 240
            CDSs (without protein)            :: 240
            Pseudo Genes (ambiguous residues) :: 0 of 240
            Pseudo Genes (frameshifted)       :: 147 of 240
            Pseudo Genes (incomplete)         :: 97 of 240
            Pseudo Genes (internal stop)      :: 45 of 240
            Pseudo Genes (multiple problems)  :: 43 of 240
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:55:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3700780
            Orig. end                         :: 3722392
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP103352.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from (56048) 61-27
            Minsokmaeul-gil Sunchang county, Jeonbuk, South Korea.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="8"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     gene            complement(29..1168)
                     /gene="acdA"
                     /locus_tag="NX823_RS19740"
                     /old_locus_tag="NX823_19740"
     CDS             complement(29..1168)
                     /EC_number="1.3.99.-"
                     /codon_start=1
                     /gene="acdA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391598.1"
                     /locus_tag="NX823_RS19740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19740"
                     /product="acyl-CoA dehydrogenase AcdA"
                     /protein_id="WP_069837822.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.2e-40, bitscore:
                     136.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.8e-26, bitscore:
                     89.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.4e-52, bitscore:
                     175.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFSLSEEHQMIRKLVRDFAKHEVAPTAAERDEQERFDRELFREM
                     ANLGLTGIPWPEDYGGIGSDYLAYVIAVEELSKVCASTGVTLSAHISLCSWPLFAFGTE
                     EQKTEYLTQLALGEKIGAFALTEARSGSDAGSMKTTAERIGDDYVLNGSKVFITNGGVA
                     DIYIVFAVTDPEKKKKGITAFIVEKDFEGFFTGKKEKKLGIRSSPTTEIMFEDCVVPAS
                     KRLGQEGEGFKIAMKTLDGGRNGIAAQAVGIAQGALDAALQYAKERKQFGKSIGEQQGI
                     AFKLADMATMIEALRLLTYQAAWLESSGLPYGKASAMSKLMAGDTAMKVTTEAVQIFGG
                     YGYTKDYPVERYMRDAKITQIYEGTQEIQRLVISRMLAD"
     gene            complement(1165..3282)
                     /gene="fadF"
                     /locus_tag="NX823_RS19745"
                     /old_locus_tag="NX823_19745"
     CDS             complement(1165..3282)
                     /codon_start=1
                     /gene="fadF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391599.1"
                     /locus_tag="NX823_RS19745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19745"
                     /product="heterodisulfide reductase-related iron-sulfur
                     binding cluster"
                     /protein_id="WP_069837823.1"
                     /transl_table=11
                     /translation="MSGFLIANTLLFLIVTAYAVYLFVYLVKTRLAYIKLGQKEQFDQR
                     FKERLHDIWVNVFGQKKLLKDKKSGIIHVMFFYGFILVQFGAIDFIIKGLAPGRNLPLG
                     PVYPAFTFFQEIVTFLILIAVGWAFYRRYIEKLVRLKRGFKAGLVLIFIGGLMLTVLLG
                     NGMNLIWHEHGLSWSEPIASGIAFMLSGVGKTGAAVIFYIAWWIHLLFLLSFLVYVPQS
                     KHAHLIAGPANVFFNRMESAGKLEKIDFTDETKESYGAGKIEDFRQSQLLDLYACVECG
                     RCTNMCPATGTGKMLSPMDLILRLRDHLTEKGAAVTSCSPWVPAAAFRHTRGNQLAAAS
                     AGSGSQEAAAALDYNPSLIGDVITEEEIWACTTCRNCEDQCPVMNEHVDKIIDLRRYLV
                     LTEGKMDSDAQRAMTSIERQGNPWGLNRKERENWRDEAPDAEIPTVKEMKKEGKEFEYL
                     FWVGSMGSYDNRSQKIAISFAKLLNHAGVSFAILGNKEKNSGDTPRRLGNEFLFQELAE
                     KNISEFEKNDVKKIVTIDPHAYNLFKNEYPDFGFEGEVYHHTEVLAELVKNGKLKPQHP
                     LHETITFHDSCYLGRYNEVYDPPREILKGIPGVQLVEMERNRETGMCCGAGGGLMWMEE
                     ETGNRINVARTEQALAVNPSVISSGCPYCLTMLGDGTKAMEAEDQVKTYDVVELLAQSV
                     LGADLKMGEKQ"
     gene            3437..4633
                     /gene="cls"
                     /locus_tag="NX823_RS19750"
                     /old_locus_tag="NX823_19750"
     CDS             3437..4633
                     /GO_function="GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cls"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391600.1"
                     /locus_tag="NX823_RS19750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19750"
                     /product="cardiolipin synthase"
                     /protein_id="WP_017696271.1"
                     /transl_table=11
                     /translation="MKVFIVIMIIVVIFFALILLDIFMGRAGYRKKAYEPVFSKKKSDI
                     ELIHCGADLVERMMKDIRQAASSVHMMFFIMKNDEVSHNMYTLLKAKAQAGVSVYLLLD
                     WSGSQKIKKPALQTMKNAGVQVHFLNKPRFPFFFFHMQKRNHRKITVIDGKIGYIGGFN
                     IAEEYLGKKAKFGNWEDYHLRMKGEGVHDLQTVFASDLKRNTGIELGSEVWPKLQQGTI
                     SHKIYATDGYSLENKYLANIAQAKNRLTVCTPYYIPSKPLQEALINARKNGVSVRIIVP
                     MKSDHPLVREAAFTYYSELLDAGCLIYRYYQGFYHVKALIIDDHLSIIGSANFDKRSLF
                     LNEEVNVEIDDEAFTSEVYATIEEDMKKSERLTMEDFSKRTFRQRPAEWLGRALSYFL"
     gene            4646..5608
                     /gene="uvsE"
                     /locus_tag="NX823_RS19755"
                     /old_locus_tag="NX823_19755"
     CDS             4646..5608
                     /GO_function="GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0009650 - UV protection [Evidence IEA]"
                     /codon_start=1
                     /gene="uvsE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391601.1"
                     /locus_tag="NX823_RS19755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19755"
                     /product="UV DNA damage repair endonuclease UvsE"
                     /protein_id="WP_069837824.1"
                     /transl_table=11
                     /translation="MIFRFGFVSNAMSLWDASPAKTLTFARYSKLSKTERKEALLTVTK
                     ANLRNTMRTLHYIIGHGIPLYRFSSSIVPLATHPDVMWDFVTPFQKEFREIGELVKTHQ
                     LRTSFHPNQFTLFTSPKESLTKNAVTDMAYHYRMLEAMGIADRSVINIHIGGAYGNKDT
                     ATAQFHQNIKQLPQEIKDRMTLENDDKTYTTEETLQVCEQEDVPFVFDFHHFYANPDDH
                     VDLNVALPRMIKTWERIGLQPKVHLSSPKSEQAIRSHADYVDANFLLPLLERFRQWGTN
                     IDFMIEAKQKDKALLRLMDELSSIRGVKRLGGGALQWKS"
     gene            5689..5961
                     /locus_tag="NX823_RS19760"
                     /old_locus_tag="NX823_19760"
     CDS             5689..5961
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391602.1"
                     /locus_tag="NX823_RS19760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19760"
                     /product="hypothetical protein"
                     /protein_id="WP_003227597.1"
                     /transl_table=11
                     /translation="MKNIKSLKVAAQAFTLRNLIHLYKMCHSGSHEVYIYSKKTMCKIK
                     SLIELETFRMAHNEKEYLIVVEGTKASQLIEKFQNLIEPAEREAL"
     misc_feature    complement(6053..6069)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.82"
                     /tool="antismash"
     gene            6098..7449
                     /locus_tag="NX823_RS19765"
                     /old_locus_tag="NX823_19765"
                     /pseudo=""
     CDS             6098..7449
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611967.1"
                     /locus_tag="NX823_RS19765"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="NX823_19765"
                     /product="IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFHTRNSSQNTAEFVLLDQLVEEDHLLRKIDKHIDSLSSLKR"
     gene            complement(7591..9261)
                     /gene="argS"
                     /locus_tag="NX823_RS19770"
                     /old_locus_tag="NX823_19770"
     CDS             complement(7591..9261)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="NX823_RS19770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19770"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_003227570.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9258..9686)
                     /gene="ywiB"
                     /locus_tag="NX823_RS19775"
                     /old_locus_tag="NX823_19775"
     CDS             complement(9258..9686)
                     /codon_start=1
                     /gene="ywiB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="NX823_RS19775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19775"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_014481216.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVKGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     misc_feature    9893..9908
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="NX823_RS19780"
                     /old_locus_tag="NX823_19780"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="NX823_RS19780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19780"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 9.3e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="NX823_RS19780_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="NX823_RS19780_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10241
                     /gene="sboX"
                     /locus_tag="NX823_RS19785"
                     /old_locus_tag="NX823_19785"
     CDS             10089..10241
                     /codon_start=1
                     /gene="sboX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="NX823_RS19785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19785"
                     /product="bacteriocin-like protein SboX"
                     /protein_id="WP_010886632.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIHT
                     QPFFI"
     gene            10266..11612
                     /gene="albA"
                     /locus_tag="NX823_RS19790"
                     /old_locus_tag="NX823_19790"
     CDS             10266..11612
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="NX823_RS19790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19790"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_069837825.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1081.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5.2e-29,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.4e-07, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1.5e-44, bitscore:
                     150.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.4e-06, bitscore: 24.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.1e-21, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.3e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.7e-09, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRAIR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIIHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10281..10556
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_NX823_RS19790_Subtilosin_rSAM_RRE.1"
                     /evalue="3.40E-31"
                     /identifier="RREFam018.1"
                     /label="NX823_RS19790"
                     /locus_tag="NX823_RS19790"
                     /protein_end="97"
                     /protein_start="5"
                     /score="98.4"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            11625..11786
                     /gene="albB"
                     /locus_tag="NX823_RS19795"
                     /old_locus_tag="NX823_19795"
     CDS             11625..11786
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="NX823_RS19795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19795"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            11783..12502
                     /gene="albC"
                     /locus_tag="NX823_RS19800"
                     /old_locus_tag="NX823_19800"
     CDS             11783..12502
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="albC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="NX823_RS19800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19800"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_069837826.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQQKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKTREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12495..13805
                     /gene="albD"
                     /locus_tag="NX823_RS19805"
                     /old_locus_tag="NX823_19805"
     CDS             12495..13805
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="NX823_RS19805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19805"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /protein_id="WP_258994137.1"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLSAALMPAATLPLCAVHMLWAVVIDFPVFLQAPPQQSRMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKGKTMFWAKYRFYSGLLAGEFLLVVMIVGFISGHPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPFFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     gene            13795..14955
                     /gene="albE"
                     /locus_tag="NX823_RS19810"
                     /old_locus_tag="NX823_19810"
     CDS             13795..14955
                     /codon_start=1
                     /gene="albE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="NX823_RS19810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19810"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_080480890.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 5.3e-05,
                     bitscore: 21.3, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDDFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKTFADLSFPS
                     SLSFEAVEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRKDRIKAIHP
                     KRFHDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRHVFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            14960..16240
                     /gene="albF"
                     /locus_tag="NX823_RS19815"
                     /old_locus_tag="NX823_19815"
     CDS             14960..16240
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="albF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="NX823_RS19815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19815"
                     /product="pitrilysin family protein"
                     /protein_id="WP_069837829.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.6e-13, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQTHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLLTIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQAAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     gene            16237..16938
                     /gene="albG"
                     /locus_tag="NX823_RS19820"
                     /old_locus_tag="NX823_19820"
     CDS             16237..16938
                     /codon_start=1
                     /gene="albG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="NX823_RS19820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19820"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbG"
                     /protein_id="WP_069837830.1"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMAAYSFGWVQAVAEAAAHYIQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDGYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGVLAAAGIWWMLSFTISELLFLIILAAIQQIRSFIYKR
                     FSYRSTASLDL"
     gene            complement(16944..18320)
                     /gene="ywhL"
                     /locus_tag="NX823_RS19825"
                     /old_locus_tag="NX823_19825"
     CDS             complement(16944..18320)
                     /codon_start=1
                     /gene="ywhL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="NX823_RS19825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19825"
                     /product="YncE family protein"
                     /protein_id="WP_069837831.1"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPKGFKVDSAEAS
                     AAVTWSTDNLSCVSEPCLIQTGPETEDIGVRYAVRVQGTIMLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSDRCPDFSQMTVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTILFSAVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEYAYVMAAGSIYMIDTANQSVIDVIAIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFNRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVPLPGAFDPAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVKVIPVGAGPSAIVM
                     "
     misc_feature    18287..18304
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(18359..19710)
                     /gene="ywhK"
                     /locus_tag="NX823_RS19830"
                     /old_locus_tag="NX823_19830"
                     /pseudo=""
     CDS             complement(18359..19710)
                     /codon_start=1
                     /gene="ywhK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="NX823_RS19830"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19830"
                     /product="YncE family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISNITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSI"
     gene            complement(19707..19937)
                     /locus_tag="NX823_RS21985"
                     /pseudo=""
     CDS             complement(19707..19937)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="NX823_RS21985"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQIPPFIILYMSYFIINILVRSAKKPQFFLSLHRMFGDIFSKRSF
                     YPQ"
     misc_feature    19891..19907
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19940..21085
                     /gene="rapF"
                     /locus_tag="NX823_RS19835"
                     /old_locus_tag="NX823_19835"
     CDS             19940..21085
                     /codon_start=1
                     /gene="rapF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="NX823_RS19835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19835"
                     /product="response regulator aspartate phosphatase RapF"
                     /protein_id="WP_069837832.1"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAVSHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAITYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYADLEDFT
                     IDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     gene            21069..21188
                     /gene="phrF"
                     /locus_tag="NX823_RS19840"
                     /old_locus_tag="NX823_19840"
     CDS             21069..21188
                     /codon_start=1
                     /gene="phrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391627.1"
                     /locus_tag="NX823_RS19840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NX823_19840"
                     /product="phosphatase RapF inhibitor PhrF"
                     /protein_id="WP_009968329.1"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFVATTIANAPTHQIEVAQRGMI"
     misc_feature    complement(21262..21278)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.82"
                     /tool="antismash"
ORIGIN
        1 gagtgatccg actgagagat gttttccgtt aatccgcgag cattctggag atgaccagtc
       61 tttgaatttc ttgagtgcct tcatagattt gcgtgatttt tgcatcacgc atatagcgtt
      121 ctaccggata atcttttgta tagccgtagc cgccgaaaat ctgcacggct tcagtcgtta
      181 ccttcatcgc cgtatcccca gccatcagtt tggacatagc ggaagctttt ccatatggaa
      241 ggcccgatga ttctaaccac gcagcctgat aggtcaatag ccttaaggct tctatcattg
      301 tcgccatatc cgcgagttta aaagcgatgc cctgctgctc gccgatcgat tttccgaatt
      361 gctttcgctc ttttgcatat tgaagcgccg catcaagcgc tccttgggcg atgcctacgg
      421 cttgtgcagc tatgccgttt ctgcctccgt caagcgtctt catcgcgatt ttgaagcctt
      481 ctccttcttg tccaagacgc tttgatgcgg gcactacaca atcttcgaac atgatttccg
      541 ttgtcggtga agaacggatg cccagcttct tttctttctt gcctgtaaaa aatccttcaa
      601 aatccttttc tactataaaa gcggtaatgc cttttttctt tttctcggga tcggtgacgg
      661 caaaaacaat gtaaatatca gcaacgccgc cgtttgtgat aaacactttg gaaccattta
      721 acacatagtc atcgccgatt cgttcagcag ttgttttcat gctgccggcg tcagatccag
      781 accgtgcttc ggtcaatgcg aatgcgccga ttttctctcc gagggccagt tgtgttaagt
      841 actctgtctt ctgttcctcc gtcccaaagg caaacagggg ccagctgcaa agagagatat
      901 gggcggaaag cgtcactccg gtggaggcgc acacttttga cagctcctcc accgcgatga
      961 cgtaggccaa atagtcactt ccgattccgc cgtaatcttc aggccatgga attcccgtca
     1021 gccccagatt tgccatttcc cgaaacagct cgcgatcgaa gcgttcttgt tcgtcccgtt
     1081 ctgccgcagt cggggccacc tcatgcttcg caaaatcgcg caccaatttt cgtatcatct
     1141 ggtgttcttc tgataatgaa aaattcattg cttctccccc attttcagat cagcgcctaa
     1201 aacggattga gccagaagct cgacgacgtc gtacgttttg acttggtctt cagcttccat
     1261 cgcctttgtg ccgtccccaa gcattgtgag acagtacgga cagccggaac tgatcaccga
     1321 tgggttgact gcgagcgctt gctctgtcct ggcgacatta atcctgttgc ctgtttcttc
     1381 ctccatccac attaatcccc cgccagctcc gcagcacatg ccggtttccc ggtttctctc
     1441 catttcaaca agctgcacgc ccggaatgcc tttcaaaatc tctctcggcg gatcatagac
     1501 ttcattgtac cggcccaaat agcatgaatc atggaaggta atcgtctcat gaagcgggtg
     1561 ctgcggcttt aattttccgt ttttcacaag ctcggccagc acttctgtat gatgataaac
     1621 ctcgccttca aatccgaaat ccggatattc gtttttaaat aaattgtatg catggggatc
     1681 gatcgtaacg atttttttga catcattttt ttcaaattca gaaatattct tctcagccag
     1741 ctcttggaac aaaaattcat ttccgaggcg gcgcggcgtg tctcctgaat ttttttcttt
     1801 attgccgagg atcgcgaagg acacgcccgc gtgattgagc agcttggcaa aggaaattgc
     1861 gattttctgg cttctgttgt cgtaagaccc catggagcct acccagaaaa ggtactcaaa
     1921 ttcttttcct tcttttttca tttcttttac agtcggaatc tcagcatccg gcgcctcatc
     1981 acgccaattt tcacgttcct tgcggttgag tccccacgga ttcccctgcc gctcaatact
     2041 tgtcattgcg cgctgggcgt cactgtccat ttttccttct gtcagtacga ggtagcggcg
     2101 gaggtcgatg attttatcca cgtgctcatt catgaccggg cattgatcct cacagtttcg
     2161 gcaagtggtg catgcccaaa tttcttcctc tgtgatgacg tcgccgatca agcttggatt
     2221 gtaatcaagc gccgctgcgg cttcctgcga tccgctgccc gctgacgccg cagccagctg
     2281 attgcctctc gtatgccgaa acgctgctgc gggcacccat ggggagcacg aggtgacggc
     2341 agcgcctttt tccgtgagat ggtctctgag acgtaaaatc aagtccatcg gagacagcat
     2401 ttttccggtg cctgttgcag ggcacatatt ggtacagcgg ccgcactcga cacacgcgta
     2461 cagatcaagc agctgagact gcctgaaatc ctcaattttt cccgctccgt agctttcttt
     2521 cgtttcgtcg gtaaaatcaa ttttttcaag ttttccggca gattccattc tattgaaaaa
     2581 gacgtttgcc gggccggcga ttaaatgggc atgcttagac tgaggcacgt acactaaaaa
     2641 gctaagcaag aacagaagat ggatccacca tgcgatatag aaaatcaccg ccgcacctgt
     2701 tttcccgact ccgctaagca taaacgcaat acctgaggca attggctcgc tccaagaaag
     2761 cccatgctca tgccaaatca gattcatccc gttcccaagc agaacggtca gcattaaacc
     2821 tccgataaaa atgagaacga gtccggcttt gaaaccgcgt ttcagcctca cgagcttttc
     2881 gatgtaacgt ctgtagaatg cccacccaac agcaattaaa atgagaaacg taacaatttc
     2941 ctgaaaaaag gtgaaggcgg gatagaccgg gccaagcggc agattccggc cgggagccag
     3001 tcctttaatg ataaagtcaa ttgctccgaa ctgaaccaat ataaatccgt agaaaaacat
     3061 gacgtgaatg attccgcttt tcttgtcctt gagcagtttt ttctgtccga atacattcac
     3121 ccatatgtcg tgaagccgtt ccttgaaccg ttgatcaaat tgttctttct ggccgagctt
     3181 gatgtaggcc agtctcgttt tgaccaaata cacaaacaaa tagacagcgt aagcggttac
     3241 aatcagaaat aataatgtat ttgcgatgag aaagccgctc attccaattc ccccttttta
     3301 ctgataaaga ccgcgatcct ctacccccga atctgtataa gattatcttt atgataaata
     3361 atgaatgagt gttcagtcaa taattaaatt cctgctgttc gggcacacta cctttactac
     3421 ggaaaggagt gccggtatga aagtatttat cgtgattatg atcattgtcg ttattttctt
     3481 tgccttgatt ctgcttgata tcttcatggg ccgtgccgga tacagaaaaa aggcgtacga
     3541 gcctgttttt tcaaaaaaga agagtgacat cgaattgatc cactgcggcg ctgatctcgt
     3601 tgagcggatg atgaaggata ttcgccaggc cgcctcttct gttcacatga tgttttttat
     3661 tatgaaaaat gatgaggtca gccacaatat gtataccttg ctgaaagcaa aagcacaagc
     3721 cggtgtttct gtttatttgc tgctggattg gtccggcagc caaaaaatta aaaagccggc
     3781 gctgcagacg atgaaaaatg ccggggttca ggttcatttt cttaacaagc ctcgttttcc
     3841 ttttttcttt tttcatatgc aaaaacggaa tcaccggaag attacggtga tagacggaaa
     3901 aatcggttat atcggcgggt ttaacatcgc cgaagaatat cttggaaaga aagcgaagtt
     3961 cggcaattgg gaggattatc atttgcgtat gaagggagaa ggcgtacatg atcttcaaac
     4021 ggtttttgct tctgatctaa aacgaaatac cggaatcgaa cttggttcgg aagtttggcc
     4081 aaagcttcag caagggacta tttctcacaa aatatatgcg actgacggtt attcccttga
     4141 aaacaaatac ttggccaaca ttgcccaagc gaagaatcgc cttacggttt gcacgcctta
     4201 ttacattcca tcaaagccgc ttcaagaggc ccttattaac gcaagaaaaa acggcgtatc
     4261 cgtgagaatc attgtaccga tgaaatcaga ccatccgctg gtacgagaag cagcttttac
     4321 gtattattcg gagctcttgg atgccggctg tcttatttat cgttattatc aaggatttta
     4381 tcatgtaaaa gccctcatca tagacgacca tctcagcata atcggatcag ccaacttcga
     4441 taaacggagc ctgtttttaa atgaagaggt gaatgtcgaa attgatgacg aagcgtttac
     4501 aagtgaagtc tatgccacga ttgaggagga tatgaaaaag tcagagcggc tgaccatgga
     4561 ggatttcagc aagcgcacat tcaggcagcg cccggcggaa tggctcggca gggcattatc
     4621 ttatttctta taaaggagag ttcctatgat tttcagattc gggttcgttt caaatgcgat
     4681 gagcctttgg gatgcgtctc ccgctaaaac attgacattc gcgcgttatt caaagctttc
     4741 aaagactgaa agaaaagaag cgcttctgac tgtgacaaaa gccaatttgc gtaatacgat
     4801 gagaaccctt cactatatca tcggccacgg cattcctttg taccgttttt ccagttcgat
     4861 tgtgccgctg gctacgcatc ccgacgtgat gtgggatttt gtaacaccgt ttcaaaaaga
     4921 gtttcgggag attggagagc ttgttaaaac acatcaactg cgaacaagct ttcatccaaa
     4981 tcaattcact ctgtttacga gcccgaagga atccctcaca aaaaatgcgg taaccgatat
     5041 ggcgtatcac taccgcatgc ttgaggccat gggcattgct gatcgctccg ttatcaacat
     5101 tcatattggc ggcgcttacg gaaataaaga caccgccact gcacaatttc atcaaaatat
     5161 aaaacagctg ccgcaggaga tcaaagatcg gatgacgctt gaaaatgatg ataaaacata
     5221 tacaacggaa gaaacgcttc aggtctgtga gcaggaggat gttccgtttg tctttgactt
     5281 tcatcatttt tacgccaatc cagacgatca cgtcgacctg aatgtagcac tgccccgcat
     5341 gatcaaaacg tgggagcgga tcggccttca gccaaaggtt cacttgtctt ccccaaaatc
     5401 ggaacaagcg atacgcagcc atgccgatta tgttgacgcc aactttttgc tgccgctgtt
     5461 ggaacgcttt aggcaatggg gaacgaatat tgatttcatg attgaagcaa agcagaaaga
     5521 caaggcgctt ctccgcttga tggatgaatt aagctccatc cgcggtgtca aacgcctcgg
     5581 gggcggtgcg ctgcaatgga aatcataaat gtgcaaaaat aggtttacga cttgtcagct
     5641 ttgggaactt aggctatata agacaacaat cgatggagga gaaagatcat taaaaatatc
     5701 aagtctctga aagtagccgc acaggccttt actttaagaa atttgattca tctttataaa
     5761 atgtgccatt ccggaagcca cgaggtttat atttattcaa agaaaacgat gtgcaaaatc
     5821 aaaagcttaa ttgagcttga aacattccgc atggctcata atgaaaagga atatttgatc
     5881 gtagttgaag gaacaaaagc atcacagctc attgaaaaat tccaaaatct catcgagcct
     5941 gctgagagag aagcgctcta acttacatac aaaaaaggat agacatctgt ctatcctcag
     6001 gctgtcgaga aaatctcgac agcctttatt tttccttaaa atatccattc ttctgtaata
     6061 aaataaaaga aagacttaaa aggacggtgt ctttctcatg ttccacacaa gaaactcttc
     6121 tcaaaacaca gccgaatttg ttctgcttga ccaactcgtt gaagaggatc acctgcttcg
     6181 gaaaattgat aaacacatag actctctttc atcattgaaa aggtgaaacc ttactacagt
     6241 gaaaacaaag accgcccctc acttgatccg cttattttat ttaaaatgat gtttatcgga
     6301 tacctctatg gtatccgttc agaaagacag cttgaaaaag aaatttacta caatatggcg
     6361 tacagatggt ttctcggatt gaacataaac gacccggttc cacaccactc caccatcagc
     6421 tggaacagac gcacacgctt taaagataca accatcttcc aagacatttt tgatgagatc
     6481 gttcttcagg ccatcaatca tgacatggtg ggcggacgag tcctattcac cgactccaca
     6541 caccttaaag ccaatgccaa caagcataaa tacacaagaa aaacaattgc gcaggatacc
     6601 caaaactata tcaaggattt aaatgaagcc attcaagagg atcgggagga acacggaaaa
     6661 aagccattaa cagccaaaga ggaggtgaaa gctgaaaaag agatccgcca cagtacaacc
     6721 gatccggaaa gtggctatct gtatcgtgaa aacaaaccag aaggtttttt ctatttagat
     6781 caccgcacaa cagatatgaa atacaacatt atcaccgatg cctacgtcac accttgaaat
     6841 gtccatgatt ctgtgcctta tcttgaccga ttagaccacc aaatcgcacg atttggtttt
     6901 caagtagaag ccgtcgctct tgattccgga tatttaacga ctccgatctg taaaggatta
     6961 tctgaccgcc aaatctttgg tgtcatcgca catagacgtt atcaccctat ccgaggcttg
     7021 tttccaaaat ggaaatttca ttatgacagt gaacaagaca gatacatttg tccaaatcac
     7081 caaacactta catactcaac aactgaccga aaaggctacc ggtcatacaa atcaaatcct
     7141 gaaatatgtt cctcatgccc actgcttgaa aactgtacaa aatcaaagaa tcggcagaaa
     7201 gtgattactc gacatgtatg ggaagaacat aaagaaaagg tcagacaaaa tcgcttgtct
     7261 gtttcaggaa aaaacctcta caaaaaaaga aaagaaaaaa tagagcgaag ctttgcagat
     7321 tcaaaacagc tgcatgggct tcgctattgc aggttgaggg gaaaacgaaa tgtgagtgaa
     7381 caagttctcc tcacagccgc atgccagaac atgaagaaaa ttgccacata cctagccaag
     7441 cagggctagg catgtgggag cgctttttct gcatctgaaa cctgatgaat atctaaagaa
     7501 actgtataaa acaaaaaagc ttgtagaaaa aacgtcgttt tctctacaag ctaaggacaa
     7561 agcccgaaga ctttgtcctt ttgatcgtga ttacattttt tccggagccg atacgccgat
     7621 cagctgaagc gcattgttca gcgtaatttg cgttgccttc attaaagcca ggcgcgcacg
     7681 gcttttctct tcattttcag ggtcgatgac tttctctgcg ttgtagaagc tgtgcagagc
     7741 agaggccaga tcataaatat agtttgtgac acggtgcgga attcgttttt ccgctgcttc
     7801 cgccactgcc tctgggaagc cgccgatcgt tttcagcaga tcgtattctt tttctgattg
     7861 aatatggctg aaatcaagat ccgccgccgg tttaagtccc tgctcttccc cttggcgaag
     7921 catgctgcag attcgggcat gtgcatattg tgcataatac acagggtttt cgttagatgt
     7981 tgatacagca agatctaagt caaaatccat atgggtgtcc gcacttcgca tcgcaaagaa
     8041 gtaacgaacg gcatccaagc cgacttcttc aatcaggtca cgcatcgtta cggctttacc
     8101 ggtccgtttg ctcattttca ttttctcgcc gtttttgtaa aggtgaacga gctgaatgat
     8161 ttctacttca agcgttcctt tttcatagcc cagcgcttcg attgccgctt tcatacgcgg
     8221 gatgtagccg tggtgatcgg cgccccaaac gttgatcagc ttatcaaagc cgcggtcaag
     8281 cttgtcctta tgatacgcga tatcaggaag caggtacgtg tacgtgccgt ccttcttgat
     8341 caatacgcgg tctttatcat cgccaaacgt cgtggaacgg aaccaagtcg cgccgtcttc
     8401 ttcatagaca tggccttttt cgcggagcgc ttcaagcgcc ttgtcgattt ttccattttg
     8461 gtacagtgaa gtttctgaat accacacatc aaacggcaca cggaagtttt ccaagtcctt
     8521 gcgaagcttt tccagctcat atttcaggcc gtattcacgg aaaaacgcga ggcgttcact
     8581 ttcttcttcg ttaacgaaac gatcaccgta ttcctcagcg agacgctttc cgatcgcaat
     8641 gatatcctcg ccgcggtagc catcctccgg catcggtttt tccaatccga gtgcttcaaa
     8701 gtaacggact tcaacagaaa gcgccagatt gttgatttgg ttacccgcat cgttaatgta
     8761 gtattcgcgg cttacatcgt aacccgcttt tgaaagcacg ttgcacaagg aatcgccgac
     8821 agccgccccg cgcgcatgcc cgaggtgaag gtctcccgtc ggattcgctg atacgaattc
     8881 tacctgaact cgttcaccgt ttccgatgtt cgtttccccg tatgcttccc ctgcttccag
     8941 tacagacgga atcagctttg ttaaatattg attgttcata tagaaattga taaaacccgg
     9001 gccggcgata tccagttttt caatcgaagc ctttccttta tcaaaatggg cgacaatctc
     9061 ttcagcgatt tggcgcggcg ctttttttgc cactcttgcc agctgcatcg ccatattcgt
     9121 tgagtagtcg ccgtgtgttt tatctttcgg tgtttctaaa acaacattgg gaatctggct
     9181 ttcttcagcc agtcccgctt tcagaacggc cgctttgatt tcttctttca gcacgtcctt
     9241 catttgttcc gcaatgttca tgcgtgagtt cctccctcat acgtgatcgt catattatgt
     9301 aaatgctcct gctcgtctcc gacatgcatg tcatatgcga tgctgatacg gcctttttct
     9361 tcatcgagat cagattgaat cgattttgtg cttgttttca gctcaagctc accaaatgac
     9421 attttatatt tagcaattgt ggaagctccc tttacgaaac gctgattcat tttgacagcg
     9481 cctgacctca tgaccaggac ttcgccttcg cttactttca caatcgtttt gactttgcct
     9541 aagtcgtgtt cttcataata agatagatac actttatttt gttttacata gtaaaatccg
     9601 gtggtgcgga attcgatgac ttcttggttt ccgtcatcct cgatcacaga cttcacatgg
     9661 agtgttatcg gtgtctcttg cttcattctg acacgtcctt ttcatcattc cactttgact
     9721 tgaatagtat aatcattcgg tttgtaaact tcaactgctt ctatcttacc atcattgctc
     9781 atcagatttg aagataaacc tcataaaaag catttcctta tatagaagag aaaatcatat
     9841 cactaattac ctttagtaaa tgttacattt ttccgaaatc tatcatttcc ttttcacatt
     9901 tttttcaaaa tatatgtatt gaattagtaa tttgatagtt ttaagataaa agtacaacat
     9961 agatctgtta gaaaaacaaa aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaggatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggatatacat acacaaccgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaatga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttctgact
    10381 ttgagtattt ggatctcaac aaaacagctt acgagctctg catgcgcatg gatggccaaa
    10441 aaacagctga gcagatttta gctgagcaat gtgcagtgta tgatgaatca ccggaagacc
    10501 ataaagattg gtattacgac atgctcaaca tgctccagaa caagcaggtt atccagcttg
    10561 gaaaccgggc catccgccat accatcacca cgagcggaag caatgaattt ccgatgcccc
    10621 tgcacgccac ctttgaactg acgcaccgct gtaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcgcc tgaagcgctc ggcaccgtgt cgattgagca attcaaaaaa acggctgata
    10741 tgctgtttga taacggtgta ttgacatgcg aaatcacagg cggagaaatt tttgtccatc
    10801 caaacgccaa tgagattctt gactatgtgt gtaaaaagtt caaaaaagtc gctgtcttaa
    10861 caaacggaac actcatgcga aaagagagcc tggagctttt gaagacttac aagcaaaaaa
    10921 tcatcgtcgg catttctctt gatagtgtca attccgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgccatgtct gtcttcgaaa aaaacatgtg ggaaatccac gatatggccc
    11101 aaaaggttcg ggatctcgga gcgaaggcgt tttcttacaa ttgggttgac gatttcggaa
    11161 gaggcaggga tattatccat ccaacgaaag acgccgagca gcaccgcaag tttatggaat
    11221 acgagcaaaa tgtgattgat gagtttaaag atctgattcc gattattccc tatgagagaa
    11281 aacgcgcggc aaattgcggc gctggctgga agtccattgt gatcagcccg ttcggcgaag
    11341 tacgtccttg cgccctcttt ccaaaggaat tttcattggg aaatattttt catgattcct
    11401 atgaaagcat ctttaactcc cctctcgtcc ataaactgtg gcaagcgcag gcgccgcggt
    11461 tcagcgaaca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc gaaaaaacat ttgctcttgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgatttgtca ccagcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tctttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ttatctgttt acgctgattt tcattgccat tgccattctg ttcggaatgc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacaagt ggatttacat ttagaaaaag gcgccgttta
    11881 cgggctgctt ggggtaaacg gcgccggaaa aacgacactg attaatacgc tgacaggcgt
    11941 gaaccgcaat ttcagcgggc gctttacact gtgcggaatt gaagcggagg ccggcatgcc
    12001 gcagaaaaca tcagatcagc agaagactca ccgttacttc gccgccgatt atccgctgct
    12061 atttacagaa attacggcga aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 tttttcagag cagcagtttg ccagtttggc cgaggccttt catttttcga aatacatcaa
    12181 caggagaatt tcggagctgt ccttggggaa caggcaaaag gttgtattga tgacaggctt
    12241 attgctgcgc gctcccctat ttattttgga tgagccgctc gtcggtttgg atgtggaatc
    12301 gatagaggtt ttttatcaga aaacgcgcga gtactgtgaa gcaggcggga ccattttgtt
    12361 ttcttctcat ctgctcgatg tcgtgcaaag attttgtgat tacgcggcca ttcttcacaa
    12421 caaacagatc caaaaggtca ttccgattgg agaggagacc gatctgcggc gggaattttt
    12481 cgaggtgatc ggccatgaat aacataatcc ccatcatgtc tttgctgttc aaacagcttt
    12541 acagccggca agggaaaaag gacgccatcc gcattgccgc aggccttgtc attctggccg
    12601 tatttgaaat cgggctgatc cgccaggccg gcattgatga atcggtgttg cgcaaaacgt
    12661 atatcatact cgcgcttctc ttaatgaacg catatatggt gtttctttct gtgacatctc
    12721 aatggaagga atcttatatg aaactgagct gcctgctgcc gatttcttca cggagctttt
    12781 ggctcgccca gagtgtcgtt ttgtttgtcg atacctgttt gagaagaacg ttattctttt
    12841 ttattttacc gctgttctta tttggaaacg gaacgctgtc aggggcgcaa acattgtttt
    12901 ggctcggcag gttttcgttt tttaccgttt actccattat tttcggagtt gtgctaagca
    12961 accacttcgt caaaaagaag aacttgatgt ttctgctgca tgcggcgata ttcgcctgtg
    13021 tatgtctcag cgccgctttg atgccggccg ccacgcttcc gctttgcgcg gtgcatatgc
    13081 tgtgggcggt ggtcattgac tttcctgtct ttctgcaggc gcctccgcag cagagcagga
    13141 tgcattcatt tatgcggcga tctgagtttt cgttttacaa aagagaatgg aaccgattta
    13201 tctcttctaa agcgatgctg ttaaattacg cggtaatggc ggcgttcagc ggcttctttt
    13261 cgttccagat gatgaatacc ggcatcttca atcagcaagt gatttatatc gtgatttccg
    13321 cgcttctgct catctgctcg ccgatcgccc ttttgtactc gattgaaaaa aatgaccgga
    13381 tgctgctcat cacgcttccg atcaagggga aaacgatgtt ttgggcgaaa tatcgctttt
    13441 attcaggcct attggcaggc gaatttctcc ttgtcgtgat gattgtgggt ttcatcagcg
    13501 gccatccgat ttcagttctc acttttttgc agtgcattga gttgctgctg gcgggagctt
    13561 ttatcaggtt aactgcggat gaaaaaaggc ccttcttcag ctggcagacg gagcagcagc
    13621 tatggagcgg tttctcaaaa tatcggtctt atctgttttg tcttccccta ttcttagcca
    13681 cattagccgg caccgctgta tccttggcgg tcattccgat agccggtctg gtcatagtct
    13741 attacctgca aaaacaggat ggtggtttct ttgatacaag caaaagagaa cggcttggaa
    13801 gttaacctgc tgaagactca tcaattttca actatatcaa tcgccgcgag ctttctgaaa
    13861 ccgatcgaaa gcgcggcgga acctgaggaa gaaacgattt atttttacgg cgccgccgca
    13921 tacctgaagg agcaaatcat tgacgatttc ggttgtgctg ccggcagccg tttcatgtac
    13981 tcagcgaatc tcttttttga tcagcagctg aaaacctgcg ggacccgttt gattcaccca
    14041 ttatataatg ggaatcttca tgttgacgcc ctgatgaaaa cttttgcaga cttgtctttc
    14101 ccttcttctc tttcattcga agcagttgaa aaggccagga atgagctgct gctgaaaatc
    14161 gaaaagaaat tcactgatcc cttctcctac tcggcggcgc gcttggctga ggaggtcttc
    14221 ggaaacccga tgtacggcac aggcatgttt ggccggaaag acaggataaa ggcgattcat
    14281 cctaaacggt ttcacgacgc aacggacttt atcgttgatt tagtgtccca gcaaaaacag
    14341 ctgaacatat tgggacaagt acaagcatgt gatgttcggg gacatgcccc gcaaacgtcc
    14401 gctgtaacgt ccgaaagaat acccgtaaac cggcatgttt ttgaaacaga gacacgcagc
    14461 gctgcaggtc cttccgtctt gacactcgga tttgactgcg gagagatgaa agatgccagc
    14521 gattatatca aaatacagct aatagacgga ttactgggaa agtacggcca ttccgcttta
    14581 ttcaagcact tcagagagaa agatctggca gtctatcacg ttatcacccg ttacgatgtc
    14641 atgaacaatt tgctgcttgt ttcaatatgt acagatcagc ttcatgagat agacattccc
    14701 ccgcgcgttt tggaagctgt ctcagctttt catacagatg agcgggaact agaacaggca
    14761 aagcagtttt tacgcaatga attgctgctg caattcgatt ctcccgaagg tctattggcc
    14821 tatatgggga tcctgcgccg cttctcctgc acgaaagaag ccttgctgga tggcatctca
    14881 gcggttacat gccgtgatgt attgcaattc atagcgacca tcaattatat cggagctcat
    14941 gtagtaaggg gatgaaaaga tggaaaagaa agcctttttt caacagctgg atgaacgaac
    15001 cgatatcaga tacacagaca gcggactaaa aatattcaga ttgaaattcc cccgcgccca
    15061 cctgcggctg tgcaatgtaa aaatcgattt tggaagccgg gatgtatgta tacgggcaga
    15121 atccggtgat acactgcttc cgtatggcac agcgcatttt ttagagcatc ttctcttctg
    15181 gcataacggc cgcaatctgt acagtgattt ttttgcgcat ggcgcgcttt taaacgcatt
    15241 cactacctac accgatacca atttcatgtt tacctcatta ccggatcggc tcagacaaac
    15301 gatccccatc ctgcttgatg ctttatggaa ccactcattt gacaagaaga ttgtcgctca
    15361 ggaaaaagct gtgattacaa gcgaaattca aacagcacac cttaaccatc agctctcata
    15421 tcattatcag ctgatcagca tgctttctcc ctcctcacca gctgccgttt tccccgcagg
    15481 cagaatcgaa gatattgagg cgcttgacat cagtgattta caaaaagcct ataaggctgc
    15541 ctaccaaacc catcggatga cgctgttttt gattgggggc tcagaaaata cagaaacgct
    15601 attgcctcct cacctccagc tggaaaagcg tccggattat catgctgaaa gaaaaatcat
    15661 cccggcatgc cctccagccc tctcacaaaa aatgatgctg ggtgatgagg agcggatgga
    15721 agatacatgg accggattac agatcggcgc acttcccggg caaaacgatc tgttgacgat
    15781 caaactttat tgggatatcg cggctcgtat tctatttcaa ttagattcac cgttttttca
    15841 agagattcag caaacgtacc gcctggaaat cgatcgtttg tcagccgaga cttatatcta
    15901 tgaggatggc ggtttcttga tccttcacag tcaagggacc cattcttcag cttatatcga
    15961 tgtggcttca tactatgtca cacagaagaa agaacaggct gccgcctggc ttcaatacgg
    16021 caaggactct ttgacagacg cgatcattta tgacagcgat tatgtgcgta aatgcttcga
    16081 gtgggcagcc gagtgtgaca ggtgcgattg ctcgtttctt gacatgtacc acatcattca
    16141 agatatggat gcgcaggttt tcttgtctct cattgatgca atggcatctt ctaacaaagc
    16201 gatcattcac gtttctcaga aagaggcgat cagacaatga aaaaaaacac tgtctttacc
    16261 cttttattgc tgcttatagg tatggcggct tattccttcg gctgggttca ggccgttgcc
    16321 gaagccgccg cccactatat acagatgatc aacaatgatg ctgtacggct cggactgctg
    16381 gcttgtaccg ctgccctcct gatgctgcct gcttttctct atcttcacta tgtcacccaa
    16441 tctgtgaaaa acatgacagc agcttttcag aaactcacac agtctcatca aagctgctgt
    16501 gactttcagc aacacaactt gtgcagccga tatgcagaag acgtcaaatc gctgcgtgac
    16561 ggctataaaa acgtccgcca aacatacgtg atggctgccg tgttgtgcca agtcatcata
    16621 ttcggctgca tgttcgaaat cgttaaagcc gtccctttcc gccttcacac gccccctgcc
    16681 ctttcaatgg gacttgcgat gctactgatc ctgtatttat tgttttgcat gcgaacgtat
    16741 ttgcggcagc ttttccggca cggcagcctg ttcagaaaag tgtttgcggg agtgctggca
    16801 gcagccggga tttggtggat gctcagtttc actataagtg aactgctgtt tctgattatc
    16861 ctggctgcca tccagcaaat cagatcattt atttataagc gattctctta tcgcagcacc
    16921 gcttctcttg atctataaaa tagctacatc acaatcgcag acgggcccgc gccaaccgga
    16981 atcaccttca cggctgtata atcacttgtg cggtacacag tcacagcatt gtcgttgggc
    17041 tgtgccgcat aaatatactg tttgtccggc gttacggcgg ggtcaaaagc gccggggaga
    17101 ggcacgtttg caatgatcct ctgtctggcc gtattaacta cgtataagtt attaatgaga
    17161 aacggttcac tatatggctc tagaaaataa gctctagtac tatcgagaga aaatacaatc
    17221 gtcctcagcg tttcaaataa acggttaaag tcccctcccc tgcttaatgg tgacaaacta
    17281 atctccgtta cacctttcgg ccacagctca ccattcaaca cgtacgcaaa atttccagcg
    17341 taaggagttg caattaaact gggaaattca aatgaatcta tgatactttc taccaactgc
    17401 ccagtattta catcatattt atcaaccgac caactgcttc cattagcggt atagacatac
    17461 tgtccattcg gatcaagagc aaagtctaaa gcgccgggta tcgcgattac atcaattact
    17521 gattgattgg ccgtgtcaat catatatata gatccggcgg ccatcacgta ggcgtactca
    17581 tctgttggat caaattcgat ctttctcggt cctcctccaa cagtaatggt atttatgatg
    17641 gttaatgttt tattatcaat cactgagaca aggttggtat tcccatggag gacatacgtg
    17701 aatgctttat cgaaagtaac gcctagatta gttggcacag cagaaaacag gattgttttt
    17761 acaacagtgt ttaaatctgc atcaatgacc gaaaccgtgc tgtctccagt attggcagta
    17821 aacacatacg attgagggtc tggcgatggc ggcaaaacaa gtgtcccggc caccgtgagc
    17881 ggactgccgt agaaaggcgg cacgatgaga agatcttcca ctgtcatctg actaaaatca
    17941 ggacagcggt cagactgtgc tgcataataa acaacttgat caatctcttc agtatgaatc
    18001 acagaaaccg ccccgtctcc ttgtccatat tgatttcgca caggcgacac actgacaaga
    18061 agcataatgg tcccttgtac tctcacagca tatcgaacac caatatcttc tgtttccggc
    18121 ccagtctgga ttaagcaagg ctcactgaca caggacaaat tgtctgtact ccatgtaaca
    18181 gccgctgacg cttcggctga atcaaccttg aagcccttag ggatatctat tggcacttga
    18241 aacggcgctt cccggctaat ttcctcatca caaaaacaga aacaattttc ctgtaaagca
    18301 gaaagatcat tctttttcat gaattcacgt ccttttaaaa atgcacaaca tgcagcggtt
    18361 aaatcgtaat ggcacccggt gaaaccccaa gagatatcac agtttcctca gaataatcat
    18421 ctgtgttgta aacaatgatg ctctgctcta taaaacgagt tgcatacaga aaatcgccat
    18481 tcggggtaaa cgcatagtct gttgctgatt gcggaagatt tccaattaca cctgctccat
    18541 tcggactgac agaatataaa ttgccggtaa agtcgtcata taaatacaca cctgttccgc
    18601 tcgtaaacat tctatattgg ccgtcaggct ccagttcttg ggtattgctg atcgtaaacg
    18661 tatttaagtc aataaccgtc aaataattga ataagaattc ttgttctaag acatacgcat
    18721 accgctccgg agaatctgtt tctatggatg atacgataag ctctcgttca atcgttcctg
    18781 tgacttcacc ggtggataag tccacttttt gcactaaccc aaaattaaga acataggcga
    18841 acaacccatt ggggtcaatt gcaatatcaa aaccttctat atagacctct caacagtcaa
    18901 cgtatcaatt ccaatcacat aaatggcagt accggtgaaa acataagcaa actcatgatt
    18961 agggataaat ctaatcaatc gaggcggctg atccagcaat atagttgctg tcactgttaa
    19021 tgtgtcataa tcgatgacag aaatcacatt attgttggga tgtaagacaa acacagcgct
    19081 tttatctggc gtaatttcaa tacctgccgg attgtacgga agagcaatcg ttgtcacaac
    19141 agtatgggtg tttgtatcaa tcacagaaac tgattgatca tttggattcg ctgtaaacgc
    19201 gtagacgggt tccggctccg gtacaagcac aatcgtcccc gtcaccgata aaggactgcc
    19261 gtaaaacggc ggaacaacaa caaggttctc aatcgtgatg ttactgatat ccgggcaatc
    19321 atccggttca tcggaataat agacgacttg atcgatttct gcattgtgaa tgacggaaac
    19381 agccccatcc ccttgtccat attgatttcg cacaggtgag acactgacga gcagcgtaac
    19441 ggttccctgc agacgcactg caaattgaac accgacctca tcaggctctg gccccgtttg
    19501 aattaagcaa cggtcactga cacaagaaag gctgtctgca ttccacgtca cgtttgcaac
    19561 agcttcagcc ggatcaacga caaatccttc aggtaattca atcggcgctt gaaacatggc
    19621 ttctcggctt gcttctccct cacaaaaaca taagcactct tcttgttctg ctcctgcttt
    19681 ttctttaaag gaaagcttgt tttttctcat tccttcactt ccttttcaga catacactgc
    19741 tcacgcagat ataacagaat atggaagagt aacgtgtttg cttgtacaaa ttactgaggg
    19801 taaaagcttc tttttgaaaa tatatctcca aacatgcggt gtaacgaaag aaaaaattgc
    19861 ggtttttttg cgcttctcac aagaatgttg atgataaaat atgacatata tagaattatg
    19921 aagggaggga tttgcaaacg tgacaggtgt catatcttct tcttccatcg gagaaaagat
    19981 taacgaatgg tatatgtaca tacgccgatt cagcataccc gatgcagaat atttgcgacg
    20041 agaaatcaag caagagctgg atcaaatgga agaagatcaa gaccttcatt tgtactattc
    20101 actgatggag tttcggcaca acctgatgct tgagtacctt gaaccgttag aaaaaatgag
    20161 gattgaggaa cagccgagac tgtctgatct gctgcttgag attgataaaa aacaggctcg
    20221 tttaacaggt ctgcttgagt actattttaa tttcttcaga ggcatgtatg agctggatca
    20281 gcgggaatat ctgtcggcta ttaaattttt caaaaaggcc gaaagcaagc tgatattcgt
    20341 taaggatcgg atagagaaag ctgagttttt ctttaagatg tctgaatctt attactatat
    20401 gaaacaaacg tatttttcaa tggactatgc acggcaagca tatgaaatat acaaagaaaa
    20461 tgaagcttat aatataagat tgctgcagtg tcattcttta tttgccacca attttttaga
    20521 tttaaaacag tatgaggatg ccgtctcaca ttttcaaaaa gcttattcta tggcagaagc
    20581 tgaaaagcag ccccaattaa tgggaagaac tttgtacaat atcgggcttt gtaaaaacag
    20641 ccaaagccaa tatgaggatg ccataacata tttcaaaaga gcaatagctg tttttgaaga
    20701 atcaaatatt cttccttcct tacctcaagc gtatttttta attacacaga tccattataa
    20761 attaggaaaa atggataaag ctcatgaata tcatagtaag ggaatggctt attcacaaaa
    20821 ggccggagat gtaatatatt tatcagagtt tgaatttttg aaatctttat acttatcagg
    20881 cccggatgaa gaagcaattc aaggattttt tgattttctc gaaagtaaaa tgttgtatgc
    20941 tgatcttgaa gatttcacta ttgatgtggc aaaatattat catgaacgta aaaattttca
    21001 aaaagcttct gcttattttt tgaaggtgga acaagtaagg caacttattc aaggaggagt
    21061 gagtttgtat gaaattgaag tctaaactat tactctcttg tctggctcta agcactgtgt
    21121 tcgtggcaac aactattgca aatgcaccta cacaccaaat tgaagttgca caacgaggaa
    21181 tgatttaacc gccgtccatc ggcggtcagg ctgtcgagaa aatctcgaca gcctttattt
    21241 ttccttaaaa tatccattct tctgtaataa aataaaagaa agacttaaaa ggacggtgtc
    21301 tttctcatgt tccacacaag aaactcttct caaaacacag ccgaatttgt tctgcttgac
    21361 caactcgttg aagaggatca cctgcttcgg aaaattgata aacacataga cttctctttc
    21421 atcattgaaa aggtgaaacc ttactacagt gaaaacaaag gccgcccctc acttgatccg
    21481 cttattttat ttaaaatgat gtttatcgga tacctctatg gtatccgttc agaaagacag
    21541 cttgaaaaag aaatttacta caatatggcg tacagatggt ttctcggatt gaacataaac
    21601 gacccggttc ca
//
