LOCUS       NZ_CP102975            22113 bp    DNA     circular CON 10-JUL-2024
DEFINITION  Staphylococcus aureus strain 16CS0209 chromosome, complete genome.
ACCESSION   NZ_CP102975
VERSION     NZ_CP102975.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 2769676)
  AUTHORS   Monecke,S., Roberts,M.C., Braun,S.D., Diezel,C., Muller,E.,
            Reinicke,M., Linde,J., Joshi,P.R., Paudel,S., Acharya,M.,
            Chalise,M.K., Fessler,A.T., Hotzel,H., Khanal,L., Koju,N.P.,
            Schwarz,S., Kyes,R.C. and Ehricht,R.
  TITLE     Sequence Analysis of Novel Staphylococcus aureus Lineages from Wild
            and Captive Macaques
  JOURNAL   Int J Mol Sci 23 (19), 11225 (2022)
   PUBMED   36232529
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2769676)
  AUTHORS   Braun,S.D., Diezel,C., Reinicke,M., Linde,J. and Monecke,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-AUG-2022) Optisch-Molekulare Diagnostik und
            Systemtechnologien, Leibniz Institute of Photonic Technology (IPHT),
            Philosophenweg 7, Jena 07743, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. v2.8.3-b1695
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 181x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024741735.1-RS_2024_07_10
            Annotation Date                   :: 07/10/2024 04:01:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,704
            CDSs (total)                      :: 2,622
            Genes (coding)                    :: 2,539
            CDSs (with protein)               :: 2,539
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 40 of 83
            Pseudo Genes (incomplete)         :: 40 of 83
            Pseudo Genes (internal stop)      :: 17 of 83
            Pseudo Genes (multiple problems)  :: 14 of 83
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:15:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2476944
            Orig. end                         :: 2499057
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102975.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22113
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="opine-like-metallophore"
                     /region_number="9"
                     /rules="(CntL and CntM)"
                     /tool="antismash"
     cand_cluster    1..22113
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(CntL and CntM)"
                     /kind="single"
                     /product="opine-like-metallophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22113
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:12113](-)"
                     /cutoff="5000"
                     /detection_rule="(CntL and CntM)"
                     /neighbourhood="10000"
                     /product="opine-like-metallophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12113)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(CntL and CntM)"
                     /neighbourhood="10000"
                     /product="opine-like-metallophore"
                     /protocluster_number="1"
     misc_feature    167..176
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 15.26"
                     /tool="antismash"
     gene            181..636
                     /locus_tag="NW953_RS12195"
                     /old_locus_tag="NW953_12195"
     CDS             181..636
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501218.1"
                     /locus_tag="NW953_RS12195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12195"
                     /product="YehR family lipoprotein"
                     /protein_id="WP_000732090.1"
                     /transl_table=11
                     /translation="MKKLCSLIVVALVCVIALSACGKEQTKTYEGDVSGKHVLTSITYK
                     DDKVLKQSTINTIKYDDLGMDKDEAKKLFAKSESIFKDLKGVKYKVDYKDKKAIEHLDI
                     DYTEVDMKKLNKRLGVSTKENKDISFEKLEKQLKHRGLKEKDKMDDK"
     misc_feature    complement(221..231)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(804..2381)
                     /locus_tag="NW953_RS12200"
                     /old_locus_tag="NW953_12200"
     CDS             complement(804..2381)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501219.1"
                     /locus_tag="NW953_RS12200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12200"
                     /product="FMN-binding glutamate synthase family protein"
                     /protein_id="WP_258409399.1"
                     /transl_table=11
                     /translation="MTFLTVMQFIVNIIIIGFMLTVIVIGLIWLIKDKRQSQHSVLRNY
                     PLLARIRYISEKMGPELRQYLFSGDNEGKPFSRNDYKNIVLAGKYNSRMTSFGTTKDYQ
                     DGFYIQNTMFPMQRNEISVDNTTLLSTFIYKIANERLFSREEYRVPTKIDPYYLSDDHA
                     IKLGEHLKHPFILKRIVGQSGMSYGALGKNAITALSKGLAKAGTWMNTGEGGLSEYHLK
                     GNGDIIFQIGPGLFGVRDKEGNFSEGLFKEVAQLSNVRAFELKLAQGAKTRGGHMEAEK
                     VNEEIAKIRNVEPYKTINSPNRYEFIHNAEDLIRFVDQLQQLGQKPVGFKIVVSKVSEI
                     ETLVRTMVELDKYPSFITIDGGEGGTGATFQELQDGVGLPLFTALPIVSGMLEKYGIRD
                     KVKLAASGKLVTPDKIAIALGLGADFVNIARGMMISVGCIMSQQCHMNTCPVGVATTDA
                     KKEKALIVGEKQYRVTNYVTSLHEGLFNIAAAVGVSSPTEITADHIVYRKVDGELQTIH
                     DYKLKLIS"
     gene            2576..3325
                     /gene="lnsB"
                     /locus_tag="NW953_RS12205"
                     /old_locus_tag="NW953_12205"
     CDS             2576..3325
                     /codon_start=1
                     /gene="lnsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501220.1"
                     /locus_tag="NW953_RS12205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12205"
                     /product="CPBP family lipoprotein N-acylation protein LnsB"
                     /protein_id="WP_000072452.1"
                     /transl_table=11
                     /translation="MSNTNKHYIEEEYATEQSRFFKRDIGFIFLYIFLVNILPIIIVFL
                     TFGLVAVFTQQAPWGFSFPISMNISYLLAVIISLAIFRRMHEDAFVPMIRSQIVASAKY
                     KWHILISFTLSIVLFLLLNHFDIFALNVDSFTVFDIYPLIREYGSISLIAIFSLTIILN
                     TLICQLIFRHILIQELSRLIPLKITIVLSVILETLYYYPYINTWWEFIPALILASSATY
                     LYLKSNRNFMVSYFYQLAVILVLHIFM"
     gene            complement(3687..4880)
                     /locus_tag="NW953_RS12210"
                     /old_locus_tag="NW953_12210"
     CDS             complement(3687..4880)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501221.1"
                     /locus_tag="NW953_RS12210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12210"
                     /product="MFS transporter"
                     /protein_id="WP_000675402.1"
                     /transl_table=11
                     /translation="MKGAMAWPFLRLYILTLMFFSANAILNVFIPLRGHDLGATNTVIG
                     IVMGAYMLTAMVFRPWAGQIIARVGPIKVLRIILIINAIALIIYGFTGLEGYFVARVMQ
                     GVCTAFFSMSLQLGIIDALPEEHRSEGVSLYSLFSTIPNLIGPLVAVGIWNANNISLFA
                     IVIIFIALTTTFFGYRVTFAEQEPDTSDKIEKMPFNAVTVFAQFFKNKELLNSGIIMIV
                     ASIVFGAVSTFVPLYTVSLGFANAGIFLTIQAIAVVAARFYLRKYIPSDGMWHPKYMVS
                     VLSLLVIASFVVAFGPQVGAIIFYGSAILIGMTQAMVYPTLTSYLSFVLPKVGRNMLLG
                     LFIACADLGISLGGALMGPISDLVGFKWMYLICGMLVIVIMIMSLLKKPTPRPANSL"
     gene            complement(4892..5641)
                     /locus_tag="NW953_RS12215"
                     /old_locus_tag="NW953_12215"
     CDS             complement(4892..5641)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501222.1"
                     /locus_tag="NW953_RS12215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12215"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000590515.1"
                     /transl_table=11
                     /translation="MIKIKDVEKSYQSAHVFKRRRTPIVKGVSFECPIGATIAIIGESG
                     SGKSTLSRMILGIEKPDKGCVTLNDQPMHKKKVRRHQIGAVFQDYTSSLHPFQTVREIL
                     FEVMCQCDGQPKDVMEVQAITLLEEVGLSKAYMDKYPNMLSGGEAQRVAIARAICINPK
                     YILFDEAISSLDMSIQTQILDLLIHLRETRQLSYIFITHDIQAATYLCDQLIIFKNGKI
                     EEQIPTSALHKSDNAYTRELIEKQLSF"
     gene            complement(5634..6449)
                     /locus_tag="NW953_RS12220"
                     /old_locus_tag="NW953_12220"
     CDS             complement(5634..6449)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501223.1"
                     /locus_tag="NW953_RS12220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12220"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000173873.1"
                     /transl_table=11
                     /translation="MTLLTVKHLTITDTWTDQPLVSDVNFTLTKGETLGVIGESGSGKS
                     ITCKSIVGLNPERLRVTGDITFDGKPMLSLSEAQLKKYRGKDIAMVMQQGSRAFDPSTT
                     VGKQMFETMKVHTSMSTQEIEKTLIEYMDYLSLKDPKRILKSYPYMLSGGMLQRLMIAL
                     ALALKPKLIIADEPTTALDTITQYDVLEAFIDIKKHFDCAMIFISHDLTVINKIADRVV
                     VMKNGQLIEHGTRESVLHHPEHVYTKYLLSTKKKINDHFKHVMRGDVHD"
     gene            complement(6446..7315)
                     /gene="opp1C"
                     /locus_tag="NW953_RS12225"
                     /old_locus_tag="NW953_12225"
     CDS             complement(6446..7315)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="opp1C"
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501224.1"
                     /locus_tag="NW953_RS12225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12225"
                     /product="nickel/cobalt ABC transporter permease"
                     /protein_id="WP_000584759.1"
                     /transl_table=11
                     /translation="MIILKRLLQDKGAVIALGIIVLYVFLGLAAPLVTFYDPNHIDTAN
                     KFAGISFQHLLGTDHLGRDILTRLIYAIRPSLLYVFVALFVSVLIGSILGFLSGYFQGF
                     VDALIMRACDVMLAFPSYVVTLALIALFGMGAENIIMAFILTRWAWFCRVIRTSVMQYT
                     ASDHVRFAKTIGMNDMKIIHKHIMPLTLADIAIISSSSMCSMILQISGFSFLGLGVKAP
                     TAEWGMMLNEARKVMFTHPEMMFAPGIAIVIIVMAFNFLSDALQIAIDPRISSKDKLRS
                     VKKGVVQS"
     gene            complement(7312..8247)
                     /gene="opp1B"
                     /locus_tag="NW953_RS12230"
                     /old_locus_tag="NW953_12230"
     CDS             complement(7312..8247)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="opp1B"
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501225.1"
                     /locus_tag="NW953_RS12230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12230"
                     /product="nickel/cobalt ABC transporter permease"
                     /protein_id="WP_000472235.1"
                     /transl_table=11
                     /translation="MFKFILKRIALMFPLMIVVSFMTFLLTYITNENPAVTILHAQGTP
                     NVTPELIAETNEKYGFNDPLLIQYKNWLLEAMQFNFGTSYITGDPVAERIGPAFMNTLK
                     LTIISSVMVMITSIILGVVSALKRGKFTDRAIRSVAFFLTALPSYWIASILIIYVSVKL
                     NILPTSGLTGPESYILPVIVITIAYAGIYFRNVRRSMVEQLNEDYVLYLRASGVKSITL
                     MLHVLRNALQVAVSIFCMSIPMIMGGLVVIEYIFAWPGLGQLSLKAILEHDFPVIQAYV
                     LIVAVLFIVFNTLADIINALLNPRLREGAR"
     gene            complement(8260..9858)
                     /gene="cntA"
                     /locus_tag="NW953_RS12235"
                     /old_locus_tag="NW953_12235"
     CDS             complement(8260..9858)
                     /codon_start=1
                     /gene="cntA"
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501226.1"
                     /locus_tag="NW953_RS12235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12235"
                     /product="staphylopine-dependent metal ABC transporter
                     substrate-binding protein CntA"
                     /protein_id="WP_001229078.1"
                     /transl_table=11
                     /translation="MRKLTKMSAMLLASGLILTGCGGNKGLEEKKENKQLTYTTVKDIG
                     DMNPHVYGGSMSAESMIYEPLVRNTKDGIKPLLAKKWDVSEDGKTYTFHLRDDVKFHDG
                     TPFDADAVKKNIDAVQENKKLHSWLKISTLIDNVKVKDKYTVELNLKEAYQPALAELAM
                     PRPYVFVSPKDFKNGTTKDGVKKFDGTGPFKLGEHKKDESADFNKNDQYWGEKSKLNKV
                     QAKVMPAGETAFLSMKKGETNFAFTDDRGTDSLDKDSLKQLKDTGDYQVKRSQPMNTKM
                     LVVNSGKKDNAVSDKTVRQAIGHMVNRDKIAKEILDGQEKPATQLFAKNVTDINFDMPT
                     RKYDLKKAESLLDEAGWKKGKDSDVRQKDGKNLEMAMYYDKGSSSQKEQAEYLQAEFKK
                     MGIKLNINGETSDKIAERRTSGDYDLMFNQTWGLLYDPQSTIAAFKAKNGYESATSGIE
                     NKDKIYNSIDDAFKIQNGKERSDAYKNILKQVDDEGIFIPISHGSMTVVAPKDLEKVSF
                     TQSQYELPFNEMQYK"
     misc_feature    complement(9825..9835)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            complement(10001..11302)
                     /gene="cntM"
                     /locus_tag="NW953_RS12240"
                     /old_locus_tag="NW953_12240"
     CDS             complement(10001..11302)
                     /codon_start=1
                     /gene="cntM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     opine-like-metallophore: CntM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040598.1"
                     /locus_tag="NW953_RS12240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12240"
                     /product="staphylopine dehydrogenase CntM"
                     /protein_id="WP_258409400.1"
                     /sec_met_domain="CntM (E-value: 8.4e-214, bitscore: 707.4,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLLMIGTGPVAIQLANICYLKSDYEIDMVGRASTSEKSKRLYQ
                     AYKKEKQFEVKIQNEAHQHLEGKFEINRLYKDVKNVKGEYETVVMACTADAYYDTLQQL
                     SLETLQSVKHVILISPTFGSQMIVEQFMSKFNQDIEVISFSTYLGDTRIVDKEAPNHVL
                     TTGVKKKLYMGSTHSNSTMCQRISALAEQLKIQLEVVESPLHAETRNSSLYVHPPLFMN
                     DFSLKAIFEGTDVPVYVYKLFPEGPITMTLIREMRLMWKEMMAILQAFRVPSVNLLQFM
                     VKENYPVRPETLDEGDIEHFEILPDILQEYLLYVRYTAILIDPFSQPDENGHYFDFSAV
                     PFKQVYKNEQDVVQIPRMPSEDYYRTAMIQHIGKMLGIKTPMIDQFLNRYEASCKAYKE
                     THEDQQLSSQFNTNLFEGDKALVTKFLEINRTLS"
     gene            complement(11295..12113)
                     /gene="cntL"
                     /locus_tag="NW953_RS12245"
                     /old_locus_tag="NW953_12245"
     CDS             complement(11295..12113)
                     /codon_start=1
                     /gene="cntL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     opine-like-metallophore: CntL"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501228.1"
                     /locus_tag="NW953_RS12245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12245"
                     /product="D-histidine (S)-2-aminobutanoyltransferase CntL"
                     /protein_id="WP_001058843.1"
                     /sec_met_domain="CntL (E-value: 9.6e-130, bitscore: 429.1,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFNNEIKLILQQYLEKFEAHYERVLQDDQYIEALETLMDDYSE
                     FILNPIYEQQFNAWRDVEEKAQLIKSLQYITAQCVKQVEVIRARRLLDGQASTTGYFDN
                     IEHCIDEEFGQCSIASNDKLLLVGSGAYPMTLIQVAKETGASVIGIDIDPQAVDLGRRI
                     VNVLAPNEDITITDQKVSELKDIKDVTHIIFSSTIPLKYSILEELYDLTNENVVVAMRF
                     GDGIKAIFNYPSQETAEDKWQCVNKHMRPQQIFDIALYKKAAIKVGITDV"
     gene            complement(12124..12945)
                     /gene="cntK"
                     /locus_tag="NW953_RS12250"
                     /old_locus_tag="NW953_12250"
     CDS             complement(12124..12945)
                     /codon_start=1
                     /gene="cntK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501229.1"
                     /locus_tag="NW953_RS12250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12250"
                     /product="histidine racemase CntK"
                     /protein_id="WP_001081690.1"
                     /transl_table=11
                     /translation="MNRQVIEFSKYNPSGNMTILVHSKHDASEYASIANQLMAATHVCC
                     EQVGFIESTQNDDGNDFHLVMSGNEFCGNATMSYIHHLQESHLLKDQQFKVKVSGCSDL
                     VQCAIHDCQYYEVQMPQAHRVVPTTINMGNHSWKAIEIIYETYVHYVIPVNQVTTEIQH
                     LVETYVREQQWNHKYKTVGMMLFDEQRQFLQPLIYIPEIQSLIWENSCGSGTASIGVFN
                     NYQRNDACKDFTVHQPGGSILVTSKRCHQLGYQTSIKGQVTTVATGKAYIE"
     misc_feature    13151..13164
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.65"
                     /tool="antismash"
     misc_feature    complement(13331..13349)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 27.24"
                     /tool="antismash"
     misc_feature    complement(13334..13349)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.06"
                     /tool="antismash"
     misc_feature    13357..13368
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.59"
                     /tool="antismash"
     gene            complement(13520..14287)
                     /locus_tag="NW953_RS12255"
                     /old_locus_tag="NW953_12255"
     CDS             complement(13520..14287)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001599343.1"
                     /locus_tag="NW953_RS12255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12255"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_258409401.1"
                     /transl_table=11
                     /translation="MNIRHIRNATAVIEYGGKRILIDPMLSDKGAFEPFPNSPRQDENN
                     PLVELPLAIEDIINNIDLVILTHLHIDHFDLKAIEVLPKDIKIYTQNEADASEVEGYDF
                     TNVSVFNDVTHIGEIELIKTDAQHGHGEILKMTGHVHGLVLKHSEEPTLYLAADTVWFD
                     GVEKTLKAHHPDIVVLNGGANQFFEGGPLVMDEHDVLKVAHTLPLAQIVVVHMEAVNHW
                     HLSREDLHAFLESHELTNRVVAPNDGELLTFEK"
     gene            complement(14388..15206)
                     /locus_tag="NW953_RS12260"
                     /old_locus_tag="NW953_12260"
     CDS             complement(14388..15206)
                     /NRPS_PKS="Domain: PKS_KR (7-161). E-value: 1.5e-06. Score:
                     20.1. Matches aSDomain:
                     nrpspksdomains_NW953_RS12260_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001620216.1"
                     /locus_tag="NW953_RS12260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12260"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_258409402.1"
                     /sec_met_domain="adh_short (E-value: 5.2e-30, bitscore:
                     102.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1e-36, bitscore:
                     124.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRLENKVAVVTGASTGIGQASAIALAQEGAYVLAVDIAEAVSET
                     VDKIKSNGDKAKAYIVDIASEQQIDNFASEIREQFGHVDALFNNAGVDNAAGRIHEYPT
                     DVYDKIMNVDMRGTFLMTRMMLPLMMTKGGSIVNTASFSGQAADLYRSGYNAAKGAVIN
                     FTKSIAIEYGRDGIRANAIAPGTIETPLVDKLTGTSEDEEGKAFRENQKWMTPLGRLGK
                     PEEVGKLVVFLASDESSFITGETIRIDGGVMAYTWPGEMLSDDAWKRTLE"
     aSDomain        complement(14724..15185)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NW953_RS12260_PKS_KR.1"
                     /evalue="1.50E-06"
                     /label="NW953_RS12260_PKS_KR.1"
                     /locus_tag="NW953_RS12260"
                     /protein_end="161"
                     /protein_start="7"
                     /score="20.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAVVTGASTGIGQASAIALAQEGAYVLAVDIAEAVSETVDKIKSN
                     GDKAKAYIVDIASEQQIDNFASEIREQFGHVDALFNNAGVDNAAGRIHEYPTDVYDKIM
                     NVDMRGTFLMTRMMLPLMMTKGGSIVNTASFSGQAADLYRSGYNAAKGAV"
     CDS_motif       complement(15114..15179)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NW953_RS12260_0001"
                     /evalue="1.80E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="NW953_RS12260"
                     /protein_end="31"
                     /protein_start="9"
                     /score="11.0"
                     /tool="antismash"
                     /translation="VVTGASTGIGQASAIALAQEGA"
     misc_feature    complement(15366..15380)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 25.67"
                     /tool="antismash"
     gene            15441..16979
                     /locus_tag="NW953_RS12265"
                     /old_locus_tag="NW953_12265"
     CDS             15441..16979
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501232.1"
                     /locus_tag="NW953_RS12265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12265"
                     /product="AbgT family transporter"
                     /protein_id="WP_258409403.1"
                     /transl_table=11
                     /translation="MTSKHQQKGSIVNRFLNSVEKIGNKLPDPSVLFFLMCVGLAIMTW
                     VISLFNVSVKHPGTHQTIYIKNIISHDGFTMIMNDTIKNFSEFPALGLVLAVMIGIGVA
                     EKTGYFDKLMISVVNRAPRFLILPTIILIGILGSTAGDAATIILPPLAAMLFIKIGYHP
                     IAGLTMAYASAVGGFAANIVVGMQDALVYSFTESATRIVSDSIKTNVAMNWYFIAASVV
                     VLLPTILLVTTKLIIPRLGQYDDRLMHDDHEETSSHITDKEAHALKWANISFIVTIILL
                     IITAIPEHSFLRNAKTGSLLDDAPLINGVGLIILVVFLVPGLVYGILSKEIKNTKDLGK
                     MFGDAVGSMGTFIVIVFFAAQLLAYLKWSNLGIIAAVKGAKLLEHQNGIVLILGIIVLS
                     AMVNMLIGSASAKWGILGPIFVPMLILIGFHPAFTQVIYRVGDSITNPITPMMPYLPLL
                     LTYAQKYDKRMKLGALLSSLMPYSIALSIVWTVFVIIWFLLGIPVGPGGPIFVK"
     gene            complement(17090..17512)
                     /locus_tag="NW953_RS12270"
                     /old_locus_tag="NW953_12270"
     CDS             complement(17090..17512)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501233.1"
                     /locus_tag="NW953_RS12270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12270"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_258409404.1"
                     /transl_table=11
                     /translation="MPYNYKKQNGELMSVMSQGEKFIHQSPVNDELSALIKLLISKING
                     CHYCVDIHKKELKELGVTQMKIDEVLSFRHLDLFTDQEKVTLEFAEMLNSIKDFKKFGI
                     IDRLKSFYDEEQIIDLVFVVNQINGWNRLNIISDRL"
     misc_feature    complement(17704..17717)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.03"
                     /tool="antismash"
     gene            complement(17964..18383)
                     /locus_tag="NW953_RS12275"
                     /old_locus_tag="NW953_12275"
     CDS             complement(17964..18383)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501234.1"
                     /locus_tag="NW953_RS12275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12275"
                     /product="DUF1433 domain-containing protein"
                     /protein_id="WP_258409405.1"
                     /transl_table=11
                     /translation="MNKKHVFVIIGVILCICIVATVIYLKVKYDEKEKQKSIYYKEQQE
                     RITLYLKHNTKEPNTIKSVHFTSLKRGPMGDAVIEGYINENKKADFVAYGSPEHNYQFG
                     GDMIESEKLSELLKPANQLKSPDEIKEELDKKEGH"
     gene            complement(18410..18905)
                     /locus_tag="NW953_RS12280"
                     /old_locus_tag="NW953_12280"
                     /pseudo=""
     CDS             complement(18410..18905)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034754.1"
                     /locus_tag="NW953_RS12280"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="NW953_12280"
                     /product="DUF1433 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTKKHVFIIIGVILCICIVATVIYLKVKHDEKENFNIN"
     misc_feature    complement(18998..19007)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.8"
                     /tool="antismash"
     gene            complement(19157..19852)
                     /locus_tag="NW953_RS12285"
                     /old_locus_tag="NW953_12285"
     CDS             complement(19157..19852)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-161). E-value: 1.2e-11. Score:
                     36.8. Matches aSDomain:
                     nrpspksdomains_NW953_RS12285_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501238.1"
                     /locus_tag="NW953_RS12285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12285"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_258409406.1"
                     /sec_met_domain="adh_short (E-value: 2.9e-33, bitscore:
                     112.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVLTDKVAVVTGAGSGIGEAIATLLHEEGVKVILAGRNKDKLQN
                     VANQLAQDSVKVVPTDVTKKEEVDELIKIAQQTFGGLDIVINSAGQMLSSKITDYQVDE
                     WDSMIDVNIKGTIYTAQAALPTMLEQSSGHLINIASISGFEVTKSSTIYSATKAAVHTI
                     TQGLEKELAKTGVKVTSISPGMVDTAITAAYNPTDRKKLEPQDIAEAVLYALTQPKHVN
                     VNEITVRPV"
     aSDomain        complement(19370..19831)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NW953_RS12285_PKS_KR.1"
                     /evalue="1.20E-11"
                     /label="NW953_RS12285_PKS_KR.1"
                     /locus_tag="NW953_RS12285"
                     /protein_end="161"
                     /protein_start="7"
                     /score="36.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAVVTGAGSGIGEAIATLLHEEGVKVILAGRNKDKLQNVANQLAQ
                     DSVKVVPTDVTKKEEVDELIKIAQQTFGGLDIVINSAGQMLSSKITDYQVDEWDSMIDV
                     NIKGTIYTAQAALPTMLEQSSGHLINIASISGFEVTKSSTIYSATKAAVH"
     CDS_motif       complement(19589..19612)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NW953_RS12285_0002"
                     /evalue="5.70E-02"
                     /label="PKSI-ER_m7"
                     /locus_tag="NW953_RS12285"
                     /protein_end="88"
                     /protein_start="80"
                     /score="6.6"
                     /tool="antismash"
                     /translation="GLDIVINS"
     CDS_motif       complement(19736..19825)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NW953_RS12285_0001"
                     /evalue="4.00E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="NW953_RS12285"
                     /protein_end="39"
                     /protein_start="9"
                     /score="13.1"
                     /tool="antismash"
                     /translation="VVTGAGSGIGEAIATLLHEEGVKVILAGRN"
     misc_feature    complement(20036..20049)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.06"
                     /tool="antismash"
     gene            20152..20433
                     /locus_tag="NW953_RS12290"
                     /old_locus_tag="NW953_12290"
     CDS             20152..20433
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501239.1"
                     /locus_tag="NW953_RS12290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12290"
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_000220938.1"
                     /transl_table=11
                     /translation="MTYHERVLALRAESKRTAFDFRFEDLFSKEEWLSMSLAERQKAEK
                     AFRHEVKNMDDVRMPFSSVHDAQVKLYNVVYSYNGIKRNFKQVENEGF"
     gene            20369..20554
                     /locus_tag="NW953_RS12295"
                     /old_locus_tag="NW953_12295"
     CDS             20369..20554
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501240.1"
                     /locus_tag="NW953_RS12295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12295"
                     /product="hypothetical protein"
                     /protein_id="WP_001791851.1"
                     /transl_table=11
                     /translation="MLYILITALNVILNKLKMKDSNIISFIYSRHDRILYVNLVGNRFK
                     NNISMTKATSNIGRGF"
     gene            complement(20693..20884)
                     /locus_tag="NW953_RS12300"
                     /old_locus_tag="NW953_12300"
     CDS             complement(20693..20884)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501241.1"
                     /locus_tag="NW953_RS12300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NW953_12300"
                     /product="hypothetical protein"
                     /protein_id="WP_001224379.1"
                     /transl_table=11
                     /translation="MRKEIEALIFSDVSSYDIYVNTGVNQGLIGDIKDGYLTIDSMPYI
                     DAERLYHFAMERKSLVTN"
     misc_feature    complement(20997..21012)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
ORIGIN
        1 acgttcccta ccgctttatc gttttcaggc ttaataattt taaaaacttt gtgaggaatc
       61 cgcttcaaaa aactcatatt tacaaaaaaa ttatcaaaat ttaaattttt gaataacatc
      121 attttttagt aaatgttata atttctttat aatacaaata tcgaaagaag gcgactgact
      181 ttgaaaaaat tatgttcatt aattgtagta gcattagttt gtgtcattgc attatcagct
      241 tgtggtaaag aacaaaccaa aacatatgaa ggtgatgtta gtggtaaaca tgtactaact
      301 tctatcacat ataaagatga taaagtttta aaacagtcta caatcaacac aattaaatat
      361 gacgatctag gtatggataa agacgaagcc aaaaagttat tcgccaaatc tgaaagtatt
      421 ttcaaagacc ttaaaggcgt aaaatacaaa gtagactata aagataaaaa agcaattgaa
      481 cacttagaca tagattacac agaagttgac atgaaaaaat taaataaacg tcttggtgtt
      541 tcaactaaag aaaataaaga tattagtttt gaaaaacttg aaaagcaatt aaagcacaga
      601 ggtttaaaag aaaaagataa aatggacgac aaatagttta taacataaaa atgccctcag
      661 ataagactaa ggttacaaac cttaatccat attctgaggg ctttaatatt tgaaattctt
      721 gtgtgaccag catccactac taatataaaa ttatttgcag taacgctaaa atccgccgct
      781 ttcattttcc cgaaataaat aagttaacta atgagtttta atttataatc atgtatcgtt
      841 tgcaactcac catcgacttt tcgatataca atatgatcag cagtaatttc tgtaggactg
      901 gatacgccaa cagctgctgc aatattgaat aagccttcat gcaaacttgt tacatagttt
      961 gtgacacgat attgcttttc tccaacaatc aatgcttttt cttttttcgc atctgtcgtt
     1021 gcaacaccta caggacatgt attcatatga cattgttgac tcataataca accgacacta
     1081 atcatcatgc cacgtgcaat attaacaaaa tctgcaccta aacctagtgc aatcgcaatt
     1141 ttatctggtg tcactaactt accagatgcc gccaatttca ctttatctcg aataccatat
     1201 ttttctaaca tgccagacac aataggtaaa gctgtaaata gcggtaagcc aacaccatct
     1261 tgtaattctt ggaatgttgc accagtacca ccttcaccac catcaatcgt aataaagctt
     1321 ggatacttat ctagttccac catcgtacgt acaagtgttt caatttctga aactttgctt
     1381 actacaattt tgaatcctac tggtttttga cctaattgct gcaactgatc gacgaaacga
     1441 atcaaatctt cagcattatg aataaattcg taacggttag gtgaattgat tgttttataa
     1501 ggttcaacat ttcggatttt agcaatttct tcgtttacct tttcagcttc catatgacca
     1561 ccacgagtct tagcaccttg tgccaacttc agctcaaatg cacgtacgtt agataactgt
     1621 gcgacctctt taaataaacc ttcactaaaa ttaccttctt tatcacgaac accaaataaa
     1681 ccgggaccaa tttggaaaat gatatcccca ttacctttta aatgatattc tgataagcca
     1741 ccttcacctg tattcatcca agtgcccgct ttagctagac ctttagataa agctgtaatg
     1801 gcattttttc ctaaagcgcc gtaactcata ccagattgtc ctacgatacg ttttaaaata
     1861 aatggatgtt ttaaatgttc acctaatttt attgcatgat catcacttaa gtaataagga
     1921 tcaatctttg tcggtacacg atattcttca cgactaaata aacgctcatt cgcgatttta
     1981 taaatgaatg ttgataacaa tgttgtatta tctactgaaa tctcattacg ttgcatcgga
     2041 aacattgtgt tctgtatgta aaagccgtct tgataatctt tagtagtacc gaagctggtc
     2101 atacgagagt tatattttcc agccaaaacg atatttttat aatcattacg tgaaaaaggt
     2161 ttcccttcat tatccccaga aaataaatac tgacgtaatt ccggtcccat tttttctgaa
     2221 atatatctaa tacgtgctag taaaggataa ttccttaata cactatgttg tgattgtctt
     2281 ttatctttaa ttaaccaaat aagcccgata acaataaccg taagcatgaa gcctataatg
     2341 ataatattaa ctataaattg catgactgta agaaacgtca ttacaatccc tccccccaaa
     2401 atttcaattc aatatttatg atacacctta caaaataaaa cacaatggaa gcgcttcatt
     2461 ttataaaaca attttatgat atgtttttca ttttaaattt taatgtataa aacatacaat
     2521 acaaagtaat atgtgctaaa gtatctatat aatacaacta tttaagaggt atactatgtc
     2581 aaatacaaat aaacattaca tagaagaaga atacgctacc gaacaatcgc gttttttcaa
     2641 acgtgatatt ggatttattt tcctttatat atttttggtt aacatcttac cgatcattat
     2701 cgtcttttta acttttgggt tagtagctgt attcactcaa caagccccat ggggtttctc
     2761 ttttcctatt tcaatgaaca ttagctattt actcgcagtt attatttcac tagctatttt
     2821 tcgtcggatg catgaagatg catttgttcc aatgatacgt tcgcaaatcg ttgccagtgc
     2881 taaatataaa tggcatattc ttatatcatt tacattaagt atcgtactct ttttactttt
     2941 aaatcatttc gatattttcg cactaaatgt agattccttt actgtctttg acatttatcc
     3001 gctcattaga gaatatggtt ccatcagttt aatagctata ttttcgttaa ccattatatt
     3061 aaatactttg atttgtcaac ttattttccg tcatatttta attcaagaat taagcagatt
     3121 aataccttta aagattacaa tagtattatc cgttatcctt gaaacactgt actattatcc
     3181 atacattaat acatggtggg aattcattcc agcattgata ctagctagta gtgcgactta
     3241 cttatattta aaatcaaacc gtaattttat ggtgagctat ttctatcaat tagcagttat
     3301 actcgttttg catattttca tgtaaaattt ttcagagtat tatccattat ccatacacat
     3361 caaaaagcac acttaaaagt cagtatcaca actcactttt aagcgtgctt tatttagata
     3421 tactatcgtt ctaaaaacga gccatataga gagcctgaga cataaatcaa tgtttaatgc
     3481 tctacaaagt tatattggca gtagttgact gaacgaaaat gcgcttgtaa caagcttttt
     3541 tcaattctag tcaaccttgc cggggtggga cgacgaaata aatttttcga aaatatcatt
     3601 tctgtcccac tcccatgaat cgccatgctc aatatacctt ttaaaattta aatattcatt
     3661 aacttaatat gctttaattc acttcattaa agactatttg ctgggcgtgg tgttggtttt
     3721 ttcaataaac tcataatcat tattacaatg actaacatac cacaaattag atacatccat
     3781 ttaaatccta ctaaatcgga aataggtccc atcaatgcgc cacctaacga tatacctaag
     3841 tctgcacagg caataaataa acctaacaac atattacgac ctacttttgg taagacgaaa
     3901 cttaagtatg atgttaatgt tggatacacc attgcttgtg tcattcctat taatattgca
     3961 ctgccataga aaataattgc acctacttgc ggaccaaatg ccactacaaa tgacgcgatc
     4021 actaataatg atagtacaga taccatatat ttaggatgcc acataccatc tgacggaatg
     4081 tatttcctta agtaaaatct tgccgcaaca actgcgatgg cctgtattgt caaaaagatt
     4141 cccgcattcg cgaatcctaa actcactgtg tataacggta caaatgtact aactgcacca
     4201 aatacaatcg atgcaacaat catgataata ccactgttca acaactcttt atttttgaaa
     4261 aattgcgcaa aaacagttac agcgttaaac ggcatttttt caatcttatc tgacgtatcg
     4321 ggttcctgtt cagcaaaggt cacgcgatag ccaaagaatg ttgttgttaa tgcgataaag
     4381 ataatgacaa ttgcaaatag tgaaatatta tttgcattcc aaatacctac ggcaactaat
     4441 ggtccgatta agtttggaat cgttgaaaat agcgagtaca atgatacacc ttcagaacga
     4501 tgttcctccg gtaatgcatc aataatacct agctgtaaag acatagaaaa gaatgccgta
     4561 cacacacctt gcataacacg tgctacgaaa taaccttcta agccagtaaa accataaata
     4621 attaaagcta tggcattgat aatcaaaata attcttaata ctttaatggg accgacacga
     4681 gcaataattt gtcctgccca tggtcgaaat accattgctg ttaacatgta tgcccccata
     4741 acgataccga taacagtatt cgttgcgcct aaatcatgcc ctcgtaaagg tataaacacg
     4801 tttaagattg cattggcact aaagaacatc aatgttaata tatataatct caaaaagggc
     4861 caagccattg cacctttcat tatctcactc cttagaatga tagttgtttt tctattaatt
     4921 ctcttgtata agcattgtca cttttatgca atgcgcttgt cggaatttgt tcttctattt
     4981 ttccgttttt aaaaataatt aattgatcac ataaatacgt ggcagcttga atatcatgtg
     5041 tgataaaaat ataactcaac tgacgcgttt cacgtaaatg aatcaataaa tctaatattt
     5101 gtgtttgaat tgacatgtcg agtgaactaa tagcttcatc aaacaaaata tatttagggt
     5161 taatacatat tgcacgcgca atcgcaacac gctgtgcctc tccacctgat aacatattag
     5221 gatatttatc catgtatgcc ttagatagac caacttcttc caacaatgta attgcttgga
     5281 cttccataac atctttaggt tgtccatcac attgacacat cacttcaaat aagatttctc
     5341 taacagtctg aaatgggtgt aatgatgacg tataatcttg aaatacagca ccaatttgat
     5401 gacgtctcac tttcttctta tgcatcggtt gatcatttaa ggttacacag cctttatccg
     5461 gtttctcaat acctaatatc atacgactca acgtcgattt accgctacca ctttctccga
     5521 taatcgcaat cgtcgcaccg attgggcact caaatgacac acctttcaca ataggtgttc
     5581 gacgacgctt aaaaacatgt gcgctttgat atgacttttc aacatcttta attttaatca
     5641 tgtacatcac ccctcatcac atgtttaaaa tgatcattaa tcttcttctt agtggataat
     5701 aaatacttcg tataaacatg ttctggatga tgcaagactg attcacgcgt accatgctca
     5761 atcagttgac catttttcat cacaacaaca cggtctgcaa tcttgttaat aaccgttaaa
     5821 tcatgtgaaa tgaaaatcat cgcacagtca aagtgttttt taatatctat aaatgcttcc
     5881 agtacatcat attgtgtaat tgtatctaaa gccgttgtcg gctcatcagc aatgattaac
     5941 tttggtttca aagctaacgc taaagcaatc atcaatcgct gtaacattcc tcctgataac
     6001 atgtaaggat atgattttaa tatacgttta ggatctttca aacttaaata atccatatat
     6061 tcaatcaatg tcttttcaat ttcttgtgta gacattgacg tatgtacttt catagtctca
     6121 aacatttgtt taccgacagt agttgatggg tcaaaggcac gactaccttg ttgcatgacc
     6181 atcgcaatat ctttaccacg gtattttttc aattgtgctt ccgataacga caacattggc
     6241 ttaccatcaa aggttatatc acctgttacg cgtaatcgtt ctggatttaa acctacaatc
     6301 gatttgcatg taattgattt accgctacca ctttctccaa taacgcctaa agtttcaccc
     6361 ttagttaatg taaaattcac atcactcacg agtggttgat ctgtccaggt atctgtaatc
     6421 gtcaaatgct taactgttaa caatgtcatg attgcaccac tccttttttc acagaacgaa
     6481 gtttatcttt agaagagatg cggggatcaa tggcaatttg taaagcatcg gataagaagt
     6541 taaatgccat cactataatc actatggcaa tacctggcgc aaacatcatt tcaggatgtg
     6601 taaacatcac ttttctagct tcgttaagca tcatgcccca ctctgcagta ggcgctttga
     6661 cacctaatcc taaaaatgaa aagccagata tttgcaagat cattgaacac atcgaactac
     6721 tagagataat agcaatatct gctaatgtta acggcataat atgtttgtga ataattttca
     6781 tatcattcat accgattgtt ttagcaaatc ttacatggtc agaagcagtg tactgcataa
     6841 cacttgtacg tataacacga cagaaccatg cccaacgcgt caaaataaat gccatgataa
     6901 tattttcggc acccatacca aacaatgcaa tcaatgctaa cgttacaaca taacttggga
     6961 atgccaacat aacatcacac gcacgcatga ttaaggcgtc aacaaaccct tggaaatatc
     7021 ctgataagaa tcctaaaata gatccaataa gtacagaaac aaatagcgct acaaagacat
     7081 ataacaaact tggtctaatc gcataaatta acctagttaa aatatctcta cctaaatggt
     7141 ccgtacctag tagatgttga aaacttatgc cagcaaattt gtttgctgta tcgatatggt
     7201 taggatcata aaatgtcaca agtggtgctg ctaatcctaa aaagacatat aatacaataa
     7261 tgcctaaagc aatcactgca cctttatctt gtaataatcg ttttaaaatt atcatcgtgc
     7321 gccctccctt aatcttggat ttaatagcgc attaatgata tctgctaatg tattaaatac
     7381 aataaataat accgctacaa ttaatacata tgcttgaatg actggaaaat catgttcaag
     7441 tattgctttt aaacttaatt gacctagtcc aggccatgca aagatatact cgataacaac
     7501 tagtccaccc attatcattg gtatagacat acaaaagatt gataccgcaa cttgtaaagc
     7561 attacgcaac acatgcaaca ttaatgtgat agatttcaca ccgcttgctc ttaaataaag
     7621 tacataatct tcatttaatt gttccaccat cgagcgtcta acatttctaa agtaaatacc
     7681 agcataggca atcgtaataa cgatcactgg caatatgtaa ctttctggac ctgttaatcc
     7741 agaagtcggc aatatgttta acttcactga aacgtaaata ataagtattg aagctatcca
     7801 atatgatggt aatgcagtta gaaagaaagc cactgaacgt atcgcacgat cagtgaactt
     7861 tcctcttttt aatgcactaa ctacacctaa aataattgat gtaatcatca ccataacact
     7921 tgaaattatt gttaatttca atgtattcat aaatgctgga ccaatgcgtt cagcaacagg
     7981 atcacctgta atgtagcttg taccaaaatt aaattgcatc gcttcaagta accaattttt
     8041 atattgaatt aataatggat cattgaaacc gtacttctca ttcgtttctg caatcaactc
     8101 tggtgttaca tttggcgttc cttgtgcatg taaaattgtc acagctggat tttcatttgt
     8161 aatatacgtc aatagaaatg tcataaaact tactacaatc atcaatggaa acatgagcgc
     8221 aatacgtttt aagataaatt tgaacatcta aacgctcctt tatttatact gcatttcatt
     8281 gaatggtaat tcatactgtg attgtgtgaa tgatactttt tctaaatctt tcggcgcaac
     8341 aactgtcata ctaccgtgtg aaatagggat aaagatacct tcatcatcaa cttgtttcaa
     8401 aatgttttta taagcgtctg aacgctcttt accgttttgg attttaaatg cgtcatcaat
     8461 gctgttgtat attttatctt tattctcaat gcctgatgtt gcactttcat aaccattttt
     8521 cgctttaaat gctgcaatag tactttgtgg atcgtacaat aatccccaag tttggttgaa
     8581 cattaagtca taatcaccag aagtacgacg ttcagcaatt ttatctgatg tttcgccatt
     8641 gatgtttaac ttaataccca ttttcttaaa ttctgcttgt aagtattctg cttgttcttt
     8701 ttgacttgaa gaacctttgt catagtacat tgccatttca aggtttttac catctttttg
     8761 acgaacatcg ctgtctttac ctttcttcca accagcttca tctaataatg attctgcttt
     8821 tttaaggtca tacttacgtg ttggcatatc gaaattaatg tctgttacat ttttcgcaaa
     8881 taattgagtt gctggttttt cttgaccatc taaaatttct ttggcaattt tatctctgtt
     8941 taccatatga ccaatcgctt gtctgactgt tttgtcactg acagcgttat cttttttacc
     9001 agaattgaca actaacattt tcgtattcat aggttgacta cgcttaactt gatagtcacc
     9061 tgtatctttc aattgtttta aagagtcttt gtctaagcta tctgtacctc tatcatctgt
     9121 gaaggcaaag ttcgtttcac cttttttcat tgataggaat gctgtttcac cagcaggcat
     9181 tacttttgct tgtactttgt taagtttaga cttttcgccc cagtattgat catttttgtt
     9241 aaagtctgca gactcatctt ttttgtgttc acctaattta aatggaccag taccatcgaa
     9301 ctttttaacg ccatcttttg ttgtgccgtt tttaaagtct tttggagaca caaatacata
     9361 tggacgaggc atcgctaatt cagccaatgc aggttgatat gcttctttca aattcaattc
     9421 aaccgtgtac ttatctttaa ctttaacatt gtcaattaat gttgaaatct ttaaccaaga
     9481 atgcaatttt ttgttttctt gaactgcgtc aatatttttc ttaactgcgt cagcatcaaa
     9541 tggcgtacca tcatggaatt taacgtcatc tctcaaatgg aacgtgtatg tcttcccatc
     9601 ttcagacaca tcccattttt tagctagtaa aggcttaatc ccatctttcg tgttacgtac
     9661 aagcggctcg tatatcatac tttcagcaga catcgatcca ccgtaaacat gcggattcat
     9721 atccccgata tctttaaccg tcgtatacgt taattgcttg ttttcttttt tctcctctaa
     9781 acctttatta ccgccacaac cagttaaaat tagccctgat gcaagtaaca ttgcactcat
     9841 tttagttagt tttctcattt gcttttcctc tttctaaatt gataagttgc attacttaat
     9901 caaatcgtaa tgattatttt tctcaattat ttgcttattt ttatgtaaat gtcaaacata
     9961 attcaataat ttttttctat tataaaactt caaaccctta ttatgaaagc gttctattga
    10021 tttccaaaaa ttttgtgacg agtgccttat ctccttcaaa tagatttgta ttaaattgag
    10081 aagatagttg ttgatcttca tgtgtctcct tgtacgcctt acaacttgct tcatagcgat
    10141 ttaggaactg atcaatcatt ggcgttttga tacctagcat tttcccaata tgctgaatca
    10201 tcgctgttct gtaataatct tcacttggca ttcttggaat ttgaacaaca tcctgttcat
    10261 ttttatagac ttgcttaaat ggtacagctg aaaaatcaaa gtaatgtccg ttttcgtctg
    10321 gctgtgaaaa tggatcaatg aggattgcgg tatatcttac ataaagcaga tattcttgta
    10381 agatatctgg caagatttcg aaatgctcaa tatcaccttc atccaaagtt tcaggacgta
    10441 ctggataatt ttccttcacc ataaattgaa gcaggttgac tgacggcact ctaaatgctt
    10501 gtaaaatagc catcatttcc ttccacatta aacgcatttc acggattaat gtcatcgtta
    10561 tcggtccttc aggaaataac ttatacacat aaaccggtac atccgttcct tcgaaaatgg
    10621 ctttcaatga aaagtcattc ataaatagtg gtgggtgcac ataaagcgaa ctgttacgtg
    10681 tttcagcatg cagtggtgat tcaacgactt ctaattgaat cttcaattgt tcagctaaag
    10741 cagagattcg ttgacacatt gttgagtttg aatgtgtcga tcccatgtac aatttctttt
    10801 ttacacctgt tgtcaacaca tgattaggtg cttctttatc aacaatacgt gtatcgccaa
    10861 gataagttga aaatgaaatc acttcgatat cctgattgaa cttagacata aattgttcca
    10921 caatcatttg cgatccaaat gtcggtgaaa ttaaaatgac atgtttgaca ctttgcaaag
    10981 tttctaacga caattgctgt agtgtgtcat aataagcatc tgctgtgcat gccatgacaa
    11041 ccgtttcgta ttcaccctta acgtttttta catctttata caaacgatta atttcaaact
    11101 taccttccag atgttgatgc gcctcgtttt gtattttgac ttcaaattgt ttctcttttt
    11161 tatacgcttg atataagcgt tttgattttt ctgatgttga ggcacgtcca accatatcaa
    11221 tctcataatc tgattttaaa tagcaaatat tcgctaattg gattgcgacc ggaccagtgc
    11281 ctatcattaa taatttagac atccgtaata cctaccttta tagctgcttt tttataaagt
    11341 gctatatcaa aaatttgctg tggtctcata tgtttattca cacattgcca cttatcttcc
    11401 gctgtttctt gtgacggata attaaatatt gctttgatgc catcaccaaa gcgcattgca
    11461 actacgacat tttcatttgt taaatcatat aattcttcta aaatgctgta ctttaaagga
    11521 attgtcgagc tgaatatgat atgcgtcaca tctttgatat ctttaagttc agataccttt
    11581 tgatccgtaa ttgttatatc ttcatttggt gctaagacgt taacgattct gcgtcctagg
    11641 tcaacggctt gtggatcaat atcaataccg ataactgaag cacctgtttc ttttgctact
    11701 tgaattaacg tcattggata tgcacctgaa ccaactagca ataatttgtc attgctagct
    11761 atactacatt gtccaaactc ttcatcaata caatgttcta tattgtcaaa gtaacctgtg
    11821 gtagacgcct gtccgtctaa tagacgtcta gctctaatga cttccacttg tttaacacac
    11881 tgcgctgtaa tatattgcag cgattttatt aattgtgctt tttcttcaac gtcacgccaa
    11941 gcattaaatt gttgttcata aataggattt aaaataaatt cactatagtc atccatcaat
    12001 gtttctaatg cttcgatata ttgatcgtct tgtaatacac gctcgtaatg cgcttcaaac
    12061 ttttctagat attgttgtaa tatcaatttg atttcattat taaagttatt cattgtaggc
    12121 tccttattct atatatgctt ttcctgtagc tacagttgta acctgtcctt taattgaagt
    12181 ttgatatccc aattgatgac atcgctttga tgtcactaaa atactgcccc ctggctgatg
    12241 tactgtaaaa tctttgcatg cgtcattacg ttgataatta ttaaaaaccc caattgatgc
    12301 tgtaccagaa ccacagctat tttcccaaat taaactttga atttctggta tatagattaa
    12361 tggctgtaaa aattgacgtt gttcatcaaa aagcatcata cctactgttt tatatttgtg
    12421 attccattgt tgctcacgca catatgtttc aaccaaatgt tgaatttctg ttgttacttg
    12481 attaactgga atcacataat gtacatatgt ttcataaata atttctattg ctttccatga
    12541 atgattaccc atattaattg ttgttggcac aacacgatgg gcttgtggca tttgaacttc
    12601 atagtattgg caatcatgaa ttgcgcattg cactaaatcc gaacagccag ataccttcac
    12661 cttaaactgt tggtctttaa gcaaatgact ttcctgcaaa tgatgtatat atgacatcgt
    12721 cgcattaccg caaaattcat taccgctcat aactaagtga aaatcattgc catcatcatt
    12781 ttgtgttgat tctataaagc ctacctgttc acaacataca tgtgttgcgg ccatcaactg
    12841 attggcgata gatgcatatt cactagcatc atgttttgaa tgaacaagta tcgtcatatt
    12901 ccccgaagga ttatacttag aaaattctat aacctgccga ttcatacgac actcctttag
    12961 atgtattttt agagcctctg taattttaat tactagaggc tcttatgcag ttgttgcgaa
    13021 gcaagcaact gtattcctct agctctttta ccttaagtga tttttcagaa gatgaaccta
    13081 atagtttccc atctattagg taagtcatgc taatccgcaa agtggaaagc atgacttagt
    13141 aatcggttgt tgcatcaaca tgcaaccgta aaccttattt aaagttgctt cttgtggctc
    13201 tacaagcgaa tgcagttgtc cgttaactac attcacttag atgcttttac tgttttcacc
    13261 tcaactaaaa cttcaaaaaa gttgcagaaa acaaatcgta actattacga tttgtttata
    13321 tactatatta gttgagaatc attgtcaata aaggttgtaa atgaatgcac atttatattt
    13381 tgataatccc tccataaact ttgtattctc agcacattca agtctttttg aaaattttta
    13441 tcaaacaaaa aagccagctt caacgtaaaa tacgttaaaa ctagccttaa gcaatacact
    13501 tcatcaaata aacaaacatt tatttttcga aagttaataa ttcaccatca tttggcgcaa
    13561 ctactctgtt agttaattca tgtgattcta aaaatgcatg taagtcttca cgagataaat
    13621 gccaatgatt gaccgcttcc atatgcacaa caactatttg agcaagcggc aatgtatgag
    13681 cgactttcaa tacatcatgt tcatccatca ctaacggccc gccttcaaag aattgatttg
    13741 caccaccatt aagtactacg atatctggat gatgcgcttt taaagtcttc tcaacaccgt
    13801 cgaaccaaac cgtatcagca gctaaatata acgttggctc ttcagaatgt ttcagcacta
    13861 aaccgtgaac atgtcctgtc attttcaaga tttcaccatg accatgttga gcatctgttt
    13921 taatcaactc aatttctcca atgtgtgtca catcattaaa taccgaaacg tttgtaaagt
    13981 cataaccctc cacttcacta gcgtctgctt cgttttgtgt ataaatttta atatcttttg
    14041 gcaatacttc aatcgctttc agatcaaaat gatcaatatg caaatgtgtt aaaattacta
    14101 aatcgatgtt gttaatgata tcttcaattg ctaatggtag ttctacaagt ggattgtttt
    14161 catcttgtct cggtgaattc ggaaatggtt caaatgcgcc tttgtcactt aacattggat
    14221 caatcaaaat gcgtttacct ccatactcaa tcacggccgt ggcatttctt atatgtctaa
    14281 tattcatgtt aaatccccct attttatatg tctgtcattg cgacaatatg catacattgc
    14341 ctacttcatg ccaaattatt ttccactgga tatcgatttt aaaacaatta ttccaatgtc
    14401 cgcttccacg catcatcact caacatctcg ccaggccatg tgtaagccat aacaccaccg
    14461 tcaatgcgaa ttgtttcacc agtaataaat gaactctcat cagatgctaa aaagacaacg
    14521 agcttgccta cttcttctgg tttacctaaa cgtcccagcg gtgtcatcca tttctgattt
    14581 tctctaaacg ctttgccttc ctcatcttcg ctagtacctg tcagtttatc tactaacggg
    14641 gtttcaatcg tacctggtgc aatcgcatta gctcgaatgc catctctacc atattcgatt
    14701 gcaatggatt tcgtaaaatt aatcactgcc cctttcgcag cattatatcc tgagcgatac
    14761 aaatctgctg cctgtcctga aaatgaagct gtgttaacaa tagaaccacc tttagtcatc
    14821 attaaaggta acatcattct cgtcatcaaa aatgttccac gcatatctac attcataatc
    14881 ttgtcatata cgtctgttgg atactcatga attctaccag ccgcattatc cacaccggca
    14941 ttattaaata acgcatcaac atgcccaaac tgttctctaa tttctgatgc aaaattgtca
    15001 atttgttgtt cgcttgcaat atccacaata taagcctttg ctttgtcacc attactttta
    15061 attttatcga cagtctccga taccgcttca gctatgtcta ccgccaatac atacgcacct
    15121 tcttgagcta aagcgattgc agaagcttgt ccgatacctg tacttgctcc tgttacgact
    15181 gcaactttat tttccaaacg tttcattcag tcactcctat acaacatatc ttaaacttac
    15241 agtccttatt ttccactgtt caatgcttca taaacctaat agctaagtct ccaggcagtc
    15301 ttagctactc tctgctatac aatttctatt gagtaactca aaatatttaa caatattaga
    15361 tttttcattt tctgaaaatt gttacttttg agagtatttt ttgttacact ttaaatattt
    15421 aacaaagggg ggaatcattg atgacatcaa aacatcaaca aaaggggtct atcgtcaatc
    15481 gtttcttgaa tagtgttgaa aaaattggaa ataaattgcc agatcctagc gttttattct
    15541 ttttaatgtg tgtgggctta gccattatga cgtgggttat ctcattattt aatgtatctg
    15601 ttaagcatcc aggtacgcat caaaccattt atattaaaaa tataattagc catgatggat
    15661 ttacgatgat aatgaatgat acgattaaaa atttctcaga gttcccagca ttaggcttag
    15721 tactagcagt gatgattggt attggtgttg cagagaaaac aggatacttc gacaagttaa
    15781 tgatttctgt tgtgaatcgc gcaccacgtt tcttaatttt accgactatt atattaattg
    15841 gtattttagg tagtacagcc ggcgatgctg ctacaattat cttgccaccg ctcgcagcga
    15901 tgctttttat taaaattggc tatcacccta tcgctggact aacgatggca tatgcttccg
    15961 ctgtaggtgg ctttgccgca aatatagttg ttggtatgca agatgctttg gtctattcat
    16021 ttacagaatc agcaacacgt atcgtttcag attctattaa aacaaacgtt gctatgaact
    16081 ggtactttat cgcagcgagt gtcgttgtat tacttcctac gatattgcta gttacaacta
    16141 aactgattat tcctaggtta ggtcaatatg atgatcgttt aatgcatgat gatcatgaag
    16201 aaacgtcttc acatattact gacaaagaag cacatgcttt aaaatgggca aatatcagtt
    16261 tcatagtcac aattatttta ttaattatta cagccattcc tgaacatagc tttttaagaa
    16321 atgctaaaac aggcagctta ctagacgatg cgccattaat taacggcgtc ggattaatta
    16381 ttcttgtcgt atttttagta cctggattag tttatgggat tttaagcaaa gaaattaaaa
    16441 atacaaaaga cttaggtaaa atgttcggcg atgctgtagg atcaatggga acatttatcg
    16501 ttattgtgtt ttttgcagca cagctacttg cgtatttaaa gtggagtaat ttaggaatta
    16561 tcgctgctgt taaaggtgcc aaattattag aacatcaaaa cggtattgta ttgatactag
    16621 gtattattgt actgagtgca atggtcaaca tgttaatcgg aagcgcatcg gctaaatggg
    16681 gtattttagg accgatattc gtaccaatgt taatccttat cggctttcac cccgcattta
    16741 cacaagtcat ttaccgtgta ggagattcaa ttaccaatcc aattacaccg atgatgccgt
    16801 acttaccttt actattaact tatgcacaaa aatacgataa acgcatgaaa ctcggagcct
    16861 tactttctag tttaatgccg tattcaatcg cgctaagtat tgtgtggaca gtatttgtca
    16921 ttatttggtt cttattaggt atccctgttg gaccaggtgg accgatattc gttaaataat
    16981 agcattcaag gggataattt aaaatgccac tatacaagat ttgacctgta tagtggcatg
    17041 attttttatg atatagcgtt cgagatgaac tctgcattta tatgaacaat tatagtctat
    17101 cactaataat atttagtctg ttccaaccgt taatttggtt tacaacaaag acaagatcaa
    17161 taatttgttc ttcatcataa aatgatttta gccggtcaat aattccaaac ttcttaaagt
    17221 ctttgattga atttaacatt tctgcaaatt caagcgtcac tttttcttga tcagtaaata
    17281 aatctaaatg tctaaaactc aagacttcat caattttcat ttgtgttaca cccaattcct
    17341 ttaattcttt tttatggata tcaacacaat aatgacaacc gttaattttt gaaattaata
    17401 acttaatcaa tgcactaagt tcatcattaa cgggtgattg atgaataaac ttttcacctt
    17461 ggctcattac agacattaac tctccatttt gtttcttgta attatacggc atttgcaatc
    17521 tctcctttac attgtttaat accaatccag tgatactaca cttcgaacaa tattggatag
    17581 aatttgaaat tctgtataac atcttgtcaa tctgtgcttt agttaaaaca tttagcgctt
    17641 atatttaaaa aatatataaa atatgaaaac agattgaaag gatattatac cttgctctac
    17701 ccttttttat aaaaaatcac acacatttga gaaaatttga taatgtcaat aaatcacgtc
    17761 atcgacatcg ttattcggta tatattgttc ttataatggt caaactatta tttcatttaa
    17821 attaatgggg ttcgcttgtg ttaatgtact gtataaaact ggggaagtat tggtgatgat
    17881 gaagtgattt atattaattg cgaaacacct tcgatagcaa tgacatagat tattggaaga
    17941 ttaaatcaaa aataaagaag accctagtgg ccttcttttt tatctaattc ttctttgatt
    18001 tcgtcaggtg attttaattg atttgctggt tttagtaatt cacttaattt ttcactttct
    18061 atcatatctc caccaaattg ataattatgt tctggagacc catatgcaac aaaatcagct
    18121 tttttgtttt cattgatgta accttcaatt acggcatcgc ccataggtcc tctttttaaa
    18181 cttgtgaaat gcacagattt aatcgtgttt ggttctttag tattatgctt gagataaagt
    18241 gtaatacgct cctgttgttc tttatagtaa attgattttt gtttttcttt ttcgtcatat
    18301 ttcactttta aataaatgac tgtagcaact atacatatac ataatatgac accaataatt
    18361 acaaaaacat gttttttgtt cattaaagta actcctaact ttagtgactc tactttttat
    18421 ttagttcttt ttttatatca tctggtgatt ttaattgatg cgctggtttt agtaactcac
    18481 ttaatctttc acttttaatt aaatcaccta caaattgaaa gttattttca ggcgatgcat
    18541 aagcaacaaa atcatcttct ttatttttat tgatgtaacc ttcaatcact ttactaccca
    18601 taggacttgt ttccaaattt gtgaagtgta cagttttgat agtattcggt tctttggtat
    18661 tatgcttgag atagagtgtt atacgctctt gttgttcttt gtagtaatcc gctttttgtt
    18721 tttctttttc atcatatttc attttaaaat ggataccagc aacactaatt aatatgatta
    18781 atataatact agttaatatt aaaattttct ttttcgtcat gtttcacttt taaataaatg
    18841 actgtagcaa ctatacatat acataaaata acaccaataa ttataaaaac atgttttttg
    18901 gtcattaaag caactcctaa aatgtggtgg aaaatgaaaa agtttttata gttctgtaat
    18961 tatgaacatt atagattata aatcataaca ctaatatcgt cgccttcact cactcgattg
    19021 ttaaaatcac cagttactga gaattatgca aggaataatt tcctatcatg cttttatatc
    19081 attattgcct tactaatatt aacaaaaccg atagctatta cattaaatgc ctatctccca
    19141 cacttcaaac acctttttat acaggacgca ctgtaatttc attcacgtta acgtgctttg
    19201 gttgtgttaa tgcatataat actgcttctg caatatcttg tggttcaagt tttttacgat
    19261 ctgttggatt gtatgcggca gttatggctg tatctaccat tcctggagaa atacttgtta
    19321 ctttaacacc tgtctttgcc aactcttttt ctaatccttg agtaatagtg tgaactgctg
    19381 ctttcgtcgc actataaatc gtactgcttt tcgttacttc aaagccagaa atagatgcaa
    19441 tgttaataag atggccactt gattgttcta acatagttgg taatgcagcc tgtgccgtgt
    19501 atatagtgcc tttgatattc acatcaatca tactatccca ttcatctact tgataatcag
    19561 taatcttaga cgacaacatt tgccccgcac tattgataac aatatccaaa ccaccgaatg
    19621 tttgttgtgc aatttttatc aattcatcga cttcttcttt tttcgttaca tctgttggca
    19681 ctaccttcac actatcttga gctaattgat tcgccacatt ttgtagttta tctttatttc
    19741 taccggctaa gatgactttc acaccttctt catgtagtaa tgttgcaatt gcttctccaa
    19801 taccactacc tgcacctgta actactgcta ctttatctgt taatactgtc ataatgatca
    19861 actcctttga ttctttttta ttttttcagg gtaaatcata agtacatatt actatttata
    19921 cttttaaaaa gcgtatcaca attcatatgc tggttatact aactcgattt atttccgctg
    19981 ataaagtaca tttttaagtt attcgaaata tacaaatgat cgttgttcat attttttatt
    20041 tttaaaaatg ttgaaaaatc gtcacttctt tattgtaaaa acattatatt agtactaaag
    20101 ttaatactgt gatttatcat tcgattgaat gattagaggg aggaataaaa cgtgacatat
    20161 catgagcgtg ttttagcatt aagagcagaa agtaaaagaa ccgcatttga ttttcgattc
    20221 gaagatttat ttagcaaaga agaatggcta agtatgtcgc ttgcagaaag acaaaaagct
    20281 gaaaaagcat ttcgacacga agttaaaaat atggacgatg taagaatgcc cttctcaagt
    20341 gtccatgacg cccaagtaaa attatataat gttgtatatt cttataacgg cattaaacgt
    20401 aattttaaac aagttgaaaa tgaaggattc taatatcatt tcgtttatat atagcagaca
    20461 tgatagaatt ttatatgtaa atcttgtagg taatcgtttt aaaaataata taagcatgac
    20521 taaagccaca tccaatatag gacgtggctt ttagtatcgt ttcagatttg tggggagtta
    20581 gggtttactt aattaaaggg gtctgccctc aattgctcac caacgagggc aagttacatc
    20641 aatcacactt caattgccgc cgactagggg tagtaatcat tggcaataag aactagttag
    20701 tgactaacga tttacgttcc atagcaaagt gatacaaacg ctcagcatca atgtaaggca
    20761 tagaatcaat agttaggtaa ccatctttga tgtcaccaat taatccttga tttacaccag
    20821 tgttcacgta aatatcatag ctacttacgt ctgagaaaat aagcgcttca atctcttttc
    20881 tcataatcat cactccaatg tttatatatt atttatataa actctctcgt ctctctctat
    20941 ttattaactt cttacaagtc taatattaca tgaatttcca aataaataaa gagttttgtg
    21001 atgtatttca caaattcatc actattttgg aaaattaaga aatatttaat tatataaaag
    21061 tttaataagt aagaaaatat gataaaatgt agatgttctt tagacattaa aagcttctaa
    21121 catgatatgg aatccgaggt tccgatatca cattagaagc ttttttgttg tggtgattat
    21181 attaataatg gcaatatagt tttaattgct atttcaaacg ctttttctga aatttttcat
    21241 tatgtttctt taaatactct aatcgttttt catcgaaaat aatatcatct attttattgt
    21301 taccaaacat atctatatag tcaaatgata cttcttcact ataaattgga ttaccttgat
    21361 tatcaaacgt cattttataa gtgtcaaaat attggtctgt atttttttcg agtaaaattg
    21421 tatttttata atcataggct gcttcgtcat tcccctcatt catagcgtca ctaaacctcc
    21481 atatgtgaga agcagttaat ccttgtaaag actttttagt aaaatagcac aattttttac
    21541 cataaattct ttcgctttct gcataaagtt ccttacacgt taatctccat ctatattgat
    21601 ctctagtcgt atcaaatgtc gtactaacaa ctttttcatc attaatttca tgatatttaa
    21661 ttaatctttc cccttttttg ccaattatct caatcccatc aacatacttt aaaaaattaa
    21721 acagataagc aatttgattg tactttcgat cttcaaattt tatatggttt gcgaaattct
    21781 ttttttggtc tatttccttt ttagttaagt atccctttgt ataacttgat atattatatg
    21841 ctaacataag agccttaagt tcattttcat ctaactgttt atgcggatga tattgaagag
    21901 ttttgactaa aaatttaatt tgattttgcc ctgtattatc ttcattataa gatgaattaa
    21961 aagaagcatt cgtgtaaaag attttagaga ataatatttc tctttgttca ttattttttg
    22021 cattaagaaa ttttttagct tctttatgat aactactata aaaaggtttt acaaaaccta
    22081 atttaataaa ttgatttata cttttcctaa ctg
//
