LOCUS       NZ_CP090125            21588 bp    DNA     circular CON 16-SEP-2024
DEFINITION  Bacillus subtilis strain Bs96 chromosome, complete genome.
ACCESSION   NZ_CP090125
VERSION     NZ_CP090125.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4050098)
  AUTHORS   Lu,S. and Yu,J.
  TITLE     Plant growth promoting Bacillus subtilis Bs96
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4050098)
  AUTHORS   Lu,S. and Yu,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-DEC-2021) Research Center of Plant Ecology and
            Enviroment, Institute of Botany, Jiangsu Province and Chinese
            Academy of Sciences, Qianhuhoucun 1#, Nanjing 210014, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: DEC-2021
            Assembly Method :: HGAP v. Dec-2021; Canu v. Dec-2021
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024706255.1-RS_2024_09_16
            Annotation Date                   :: 09/16/2024 08:29:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,301
            CDSs (total)                      :: 4,180
            Genes (coding)                    :: 3,965
            CDSs (with protein)               :: 3,965
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 215
            CDSs (without protein)            :: 215
            Pseudo Genes (ambiguous residues) :: 0 of 215
            Pseudo Genes (frameshifted)       :: 141 of 215
            Pseudo Genes (incomplete)         :: 68 of 215
            Pseudo Genes (internal stop)      :: 37 of 215
            Pseudo Genes (multiple problems)  :: 27 of 215
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:55:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3652697
            Orig. end                         :: 3674285
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP090125.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Institute of Botany, Jiangsu
            Province and Chinese Academy of Sciences.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21588
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="7"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21588
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21588
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11588](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11588
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(2354..2369)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(2378..2391)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    2378..2392
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     gene            complement(2507..2983)
                     /gene="arfM"
                     /locus_tag="LXE94_RS19470"
                     /old_locus_tag="LXE94_19420"
     CDS             complement(2507..2983)
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="LXE94_RS19470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19420"
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_003243032.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     misc_feature    complement(3041..3056)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            3127..3846
                     /gene="ywiC"
                     /locus_tag="LXE94_RS19475"
                     /old_locus_tag="LXE94_19425"
     CDS             3127..3846
                     /codon_start=1
                     /gene="ywiC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="LXE94_RS19475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19425"
                     /product="YwiC-like family protein"
                     /protein_id="WP_014481214.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRAFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     gene            complement(3976..5328)
                     /locus_tag="LXE94_RS19480"
                     /old_locus_tag="LXE94_19430"
     CDS             complement(3976..5328)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611967.1"
                     /locus_tag="LXE94_RS19480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19430"
                     /product="IS1182 family transposase"
                     /protein_id="WP_129137591.1"
                     /transl_table=11
                     /translation="MFHTRNSSQNTAEFVLLDQLVEEDHLLRKIDKHIDFSFIIEKVKP
                     YYSENKGRPSLDPLILFKMMFIGYLYGIRSERQLEKEIYYNMAYRWFLGLNINDPVPHH
                     STISWNRRTRFKDTTIFQDIFDEIVLQAINHDMVGGRVLFTDSTHLKANANKHKYTRKT
                     IAQDTQNYIKDLNEAIQEDREEHGKKPLTAKEEVKAEKEIRHSTTDPESGYLYRENKPE
                     GFFYLDHRTTDMKYNIITDAYVTPGNVHDSVPYLDRLDHQIARFGFQVEAVALDSGYLT
                     TPICKGLSDRQIFGVIAHRRYHPIRGLFPKWKFHYDSEQDRYICPNHQTLTYSTTDRKG
                     YRSYKSNPEICSSCPLLENCTKSKNRQKVITRHVWEDHKEKIRQNRLSVSGKNLYKKRK
                     EKIERSFADSKQLHGLRYCRLRGKRNVSEQVLLTAACQNMKKIATYLAKQG"
     misc_feature    5357..5373
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.82"
                     /tool="antismash"
     gene            complement(5456..6172)
                     /gene="fnr"
                     /locus_tag="LXE94_RS19485"
                     /old_locus_tag="LXE94_19435"
     CDS             complement(5456..6172)
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="LXE94_RS19485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19435"
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="WP_003243241.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLYELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6270..7457)
                     /gene="narK"
                     /locus_tag="LXE94_RS19490"
                     /old_locus_tag="LXE94_19440"
     CDS             complement(6270..7457)
                     /codon_start=1
                     /gene="narK"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="LXE94_RS19490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19440"
                     /product="nitrate transporter NarK"
                     /protein_id="WP_014478287.1"
                     /transl_table=11
                     /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAAPVIAQAVGWKSTVQ
                     MYLVLLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSPLRILMFVFAGLTLS
                     GIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKTHTERNSQSIN"
     misc_feature    complement(7522..7537)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(7593..9263)
                     /gene="argS"
                     /locus_tag="LXE94_RS19495"
                     /old_locus_tag="LXE94_19445"
     CDS             complement(7593..9263)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="LXE94_RS19495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19445"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_003227570.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9260..9688)
                     /gene="ywiB"
                     /locus_tag="LXE94_RS19500"
                     /old_locus_tag="LXE94_19450"
     CDS             complement(9260..9688)
                     /codon_start=1
                     /gene="ywiB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="LXE94_RS19500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19450"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_014481216.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVKGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="LXE94_RS19505"
                     /old_locus_tag="LXE94_19455"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="LXE94_RS19505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19455"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 9.1e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="LXE94_RS19505_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="LXE94_RS19505_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10217
                     /locus_tag="LXE94_RS19510"
                     /old_locus_tag="LXE94_19460"
     CDS             10089..10217
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="LXE94_RS19510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19460"
                     /product="bacteriocin biosynthesis protein"
                     /protein_id="WP_257986280.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSYLLDIHTQPFFI"
     gene            10242..11588
                     /gene="albA"
                     /locus_tag="LXE94_RS19515"
                     /old_locus_tag="LXE94_19465"
     CDS             10242..11588
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="LXE94_RS19515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19465"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_024573031.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1083.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5.1e-29,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.3e-07, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1.2e-44, bitscore:
                     150.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.5e-06, bitscore: 24.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.1e-21, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.2e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.6e-09, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10257..10532
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_LXE94_RS19515_Subtilosin_rSAM_RRE.1"
                     /evalue="3.40E-31"
                     /identifier="RREFam018.1"
                     /label="LXE94_RS19515"
                     /locus_tag="LXE94_RS19515"
                     /protein_end="97"
                     /protein_start="5"
                     /score="98.4"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            11601..11762
                     /gene="albB"
                     /locus_tag="LXE94_RS19520"
                     /old_locus_tag="LXE94_19470"
     CDS             11601..11762
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="LXE94_RS19520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19470"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            11759..12478
                     /gene="albC"
                     /locus_tag="LXE94_RS19525"
                     /old_locus_tag="LXE94_19475"
     CDS             11759..12478
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="albC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="LXE94_RS19525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19475"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_129093489.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKTREYCEAGGTILFSSHLLDVVQRFCDYAAILDNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12471..13781
                     /gene="albD"
                     /locus_tag="LXE94_RS19530"
                     /old_locus_tag="LXE94_19480"
     CDS             12471..13781
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="LXE94_RS19530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19480"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /protein_id="WP_038829818.1"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCISAALMPAATLPLCAVHMLWAVIIDFPVFLQAPPQQSKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVVYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     gene            13771..14931
                     /gene="albE"
                     /locus_tag="LXE94_RS19535"
                     /old_locus_tag="LXE94_19485"
     CDS             13771..14931
                     /codon_start=1
                     /gene="albE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="LXE94_RS19535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19485"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_080015532.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 5.4e-05,
                     bitscore: 21.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALLKTFADLSFPS
                     SLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRKDRIKAIHP
                     KRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRHVFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            14936..16216
                     /gene="albF"
                     /locus_tag="LXE94_RS19540"
                     /old_locus_tag="LXE94_19490"
     CDS             14936..16216
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="albF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="LXE94_RS19540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19490"
                     /product="pitrilysin family protein"
                     /protein_id="WP_129093491.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 9e-13, bitscore:
                     46.4, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNDQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQTHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLWVIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     gene            16213..16914
                     /gene="albG"
                     /locus_tag="LXE94_RS19545"
                     /old_locus_tag="LXE94_19495"
     CDS             16213..16914
                     /codon_start=1
                     /gene="albG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="LXE94_RS19545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19495"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbG"
                     /protein_id="WP_029318695.1"
                     /transl_table=11
                     /translation="MKKSTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILATIQQIGSFIYKR
                     FSYRSTASLDL"
     gene            complement(16920..18287)
                     /gene="ywhL"
                     /locus_tag="LXE94_RS19550"
                     /old_locus_tag="LXE94_19500"
     CDS             complement(16920..18287)
                     /codon_start=1
                     /gene="ywhL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017696256.1"
                     /locus_tag="LXE94_RS19550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19500"
                     /product="YncE family protein"
                     /protein_id="WP_017696256.1"
                     /transl_table=11
                     /translation="MDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEASAAV
                     TWSTDNVSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGNGAVSV
                     IHTEEIDQVVYYAAQSGRCPDFSQITVEDLLIVPPFYGSPLTVTGTLVLPPSPDPQSYV
                     FTANTGDSTVSVIDADLNTVVKTIPFSDVPTNLGVTFDKAFTYVLHGNTNLVSVIDNKT
                     LTIINTITVGGGPRKIEFDPKDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFALDP
                     NGQYVYTANGSSWSVDKYDINTGQLVESIIDTFEFPSLIATPYAGNFAYVLNGELWPKG
                     VTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTARQRI
                     IANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM"
     misc_feature    18263..18280
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(18336..19691)
                     /gene="ywhK"
                     /locus_tag="LXE94_RS19555"
                     /old_locus_tag="LXE94_19505"
     CDS             complement(18336..19691)
                     /codon_start=1
                     /gene="ywhK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="LXE94_RS19555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19505"
                     /product="YncE family protein"
                     /protein_id="WP_095844024.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANSNDQSVSVIDTNTHSIVTTIALPYNPAGIEITPDKSAVFVSHPNNNV
                     ISVIDYDTLTVTASILLDQPPRLIRFIPNHEFAYVFTGTAVSVIGIDTLTVDRSIPVEG
                     YDVAIDPNGLFAYVLNFGIVQKVDLTTGEVTGTIERELIVSTIETNWPERYAYVLEQEF
                     FFNYLTVIDLNTFAISSTQELEYEGEYRMFTSGAEVYLYDGFTGNLYSVSPNGAGVIGN
                     VPQSARDFAFTPNGEFLYATHVLEQSITVYNTDDYSVETVISLGVSPGAITI"
     gene            complement(19688..19918)
                     /locus_tag="LXE94_RS21500"
     CDS             complement(19688..19918)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="LXE94_RS21500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_024572000.1"
                     /transl_table=11
                     /translation="MQIPPFIILYMSYFIINILVRSAKKPQFFLSLHRMFGDIFSKRSF
                     YPQQFVQANTLPFHILLYLREQCMSEKEVKE"
     misc_feature    19872..19888
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19921..21066
                     /locus_tag="LXE94_RS19560"
                     /old_locus_tag="LXE94_19510"
     CDS             19921..21066
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="LXE94_RS19560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19510"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_095844025.1"
                     /transl_table=11
                     /translation="MSGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDRREYVLAIQFFKKAESKLVFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYSEQTTYDIRMIQCQSLFGANFLDLKQYEKAIAHFQKAFTLAKTEQQPQLMG
                     RTLYNIALCKQNQNSFESAIEYVKKSIQVFEGSKMLPSLPQAFFLITQIYFKLGKIDNA
                     CEYHKKGKEYSAAAGDTVYLTEFEFLESLYLSGPDEERIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASHYFLKVEEARQHIQGGVNLYEMEV"
     gene            21050..21169
                     /locus_tag="LXE94_RS19565"
                     /old_locus_tag="LXE94_19515"
     CDS             21050..21169
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022581.5"
                     /locus_tag="LXE94_RS19565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LXE94_19515"
                     /product="PhrC/PhrF family phosphatase-inhibitory
                     pheromone"
                     /protein_id="WP_014665774.1"
                     /transl_table=11
                     /translation="MKWKYKLLLACLAVSAVFITVEVSNSSTEHFDVAQRAMI"
ORIGIN
        1 agattgatta acaagtcgag ctttccttcc ggcgcctgct cccgccattt gatttcttca
       61 gggcggatgc tgtcgctgtc gtcattcatt aaaccgttcg ttgtccccag caaatgcttg
      121 agaaaatatt catgcccttt tcctgagctt gagatcagat ttgcccgcca tacgaagaga
      181 tttcttggga aattcacttc attgtcggga tcttcaatcg cgaatttcag ttttttctct
      241 tgaagctgtg aggccacgta cgcacctacg tcttcgggtg ttactgcccc tgctttttca
      301 gcttctttat acagatcgat gccattttga ttgaaagtcg ggtaagacgg aagccacccc
      361 agccgcgccg ccagcacatt gtaatcagcg tggtgcttgt agcgggatga cgcagcaatc
      421 ggtgatgcca aatcactgat cggctggtcc tcataacgcc actgatctgt cgcaaagtag
      481 aaaaatgaag tgccgttttg cagcttgggc acgccctccc agtcctttgc agttgcaatc
      541 gtctgccatc cttcagcagg tcggagcttt tcctgcccga cgtaatgggc ccagcctccg
      601 ccatttacgc cttgggcgcc tacaagcaaa acaagattta acactgctcg gtagatcgtg
      661 tcggagttga accagtggtt aatgccggct cctacgataa tcatagaccg gccgtctgta
      721 tcgatcgcat tttgggcaaa ctctctggca atcttaacga cagcttcttt tttgattcct
      781 gtcatttgtt cctgccaggc aggcgtaaac ggctcaggat catcatagga gacagcttgt
      841 tgttcgccga tgccccgatt tacgccgtag ttagccagta tcaagtcaaa cacggtcgtg
      901 acgtacgtct cttcaccgtt caggttcatt tttttaatag gaagatcccg ctcgagcact
      961 ttgtttccgt catttgaaaa ataagggatg cgcaccgtgc cgatttcatc ctctattccg
     1021 agcacagaga gacggggttc aatcggttcc ccggtttctt catcaatcat gtgcaggttc
     1081 catttctgct gcccgtccca gcgcgagccc attgtccctt ggggtatggc aaatgaactt
     1141 gtctgttcat cccaaaccgc aggcttccac tgatcatgct ttgtcttccg cccgatgtcc
     1201 ttcgcatgca gaaaccgtcc cgctgtgtat acgccatttt cttttgacag ggtgacgaga
     1261 aatggaaaat cagtgtattg cttcgcgtac tcaataaaac gttcagtttc ttggttcacg
     1321 taaaattcct gcaaaatgac gtgacccatc gccatcgcaa gcgccccgtc agtcccttgg
     1381 cgaatactca gccagtcatc cgcgaacttt gaggattccg caaaatctgg actgatcgaa
     1441 atgaccttag cgcctttata gcgggcctcc gccaaaaaat gcgcgtcagg cgttctcgtt
     1501 aacggaacgt tggagcccca tgtgatgata tagccggaat tgtaccaatc actgctttcc
     1561 ggaacgtccg tctggtcacc ccaaatttgc ggggatgccg gaggaagatc cgcataccag
     1621 tcataaaaac tgagcatagg gcctccgatt aacgacataa accgggagcc tgatgcatgg
     1681 ctgatcatgg acatggccgg aatcggagaa aaaccgacgt ttctgtcagg cccgtatttc
     1741 atcactgtat acagcagaga ggctgaaatc agcttcagca cctccggcca ttcagcgcgc
     1801 acaaaaccgc ctttccctct cgcctgttta taggacttcg ctttttcagg gttttcgacg
     1861 atcgatttcc aggcttccaa tggattttga tgttcttgca gtgcctcccg ccataaatta
     1921 atcagtacac cgcgcacgta tggatatttc acacgcagcg ggctgtagat ataccatgaa
     1981 aaactggccc cccgcgggca gcctctcggt tcaaaatcag gcatatccgg gcctgttgat
     2041 ggataattca aattttgccc ttcccacgtg acaattccgt ttttcacata aatattccag
     2101 ctgcaagacc ctgtacagtt aacaccgtgg gtggagcgaa cgactttgtc gtactgccat
     2161 ctgtttctgt atacattctc ccaatcgcga tcttcgcggg tggtttggct atgtttattt
     2221 gaatggtgtt cgataggaga gaaataattc aatctcctaa acaacggact ccttttcttt
     2281 ttcttcatga gagttcactc cttccgagtc aggtgatgct aagttcacta taaacagaga
     2341 cagcgtgttt ccttgtgaac tatgtcacac actccgcttt tttcacaaaa tgttcacaca
     2401 aaggagaagg aaggcttttc acaggatgtg aggaaggctg cgttcaggca gaacgcttgg
     2461 gtcattagct gcctttcatt caaagatcaa aaaaaaccgg ctctatttaa gaaccgggct
     2521 cggcgttttc atcctgtgat gtatgcaaat accgcaaaaa taattgatag gaacaaaaaa
     2581 cattttgctg aagcatagcc aaaaagttca tttgcagctg cggatgataa gacatcattt
     2641 tcttaaatat gtaatatggg atgttgagaa tcagaatgtc tgaagtggca ttgactgaga
     2701 taaagggcga taaataaagc ccgccttttt catcaatcgg aaacacatcg cctttttccc
     2761 acagcgcaac ggttttcgac ccttcaggga gccttgtgtc cataaaacgg acactgcctt
     2821 ttaatacaat ataaacagat tgagaatgaa gaaaagatgg agactgatca catgaaccgc
     2881 ggataaacgt gccgtttttc agcaaggttt cgacaatgga tagaggcact tcattaaaca
     2941 taggaagttg tttcagaaat aataaatagt cacactgatt cataggaaaa cctcctgtgc
     3001 taaggatagc tttagtgtag ctcgactgag cctgtacagc agtgatgtat ttcacagcct
     3061 gtatgatgaa tgtcacttat caggagggtg aatgcattta taatgaaaga aaaaaggagg
     3121 atttcgatga aggcgctgat tccgaagcag cacggggcgt gggcgatgct gctgatccca
     3181 tttttactcg gcatggtcaa gggaggcccc gttatttggc atattccgct cttccttggt
     3241 tggcttttcc tatacttagc ggtttatccc gttacgcttg ccttaaaaaa gaaacaaagc
     3301 aaaccatatc aaaagtggat gtgttattac ggttttcccg cctgctgctt tttgatgatc
     3361 tcggtctttc ataagccgcc tctcatctgg gtgggcgttt ctttactgcc gctgtttctc
     3421 atacatatgt attttgcccg cagaaaaaac gaacgagcct tattgaatga tgttgcaggt
     3481 gtcttgttct tttgttcggg cgggtttgcg agctgctggc tggggatggg aacccttgac
     3541 ggctgggctt ggtttatttt cttgcagtct gctttatttt ttatcgggag ttccttttat
     3601 gtgaaatcgg tgatccgcga gagaaaaaac agggcatttg catactggtc atggggatat
     3661 cacctgctgc tccccttttt atccgctctt ttcggagcag gatgggcgtt tctcgctttt
     3721 atcccgagca gcttgcgggc atggtttttt catggaaggg attggcccgt aaaaacgatt
     3781 ggcattctgg aaatcgtgaa tgcctgcttc tttcttgccg tcatgtgcct gtttatcaca
     3841 aggtaaaaaa acaaggacac cgctgtcctt gtcagcttgt agagaaaacg cgttttttct
     3901 acaagctttt ttgttttata cagtttcttt agatattcat caggtttcag atgcagaaaa
     3961 agcgctccca catgcctagc cctgcttggc taggtatgtg gcaattttct tcatgttctg
     4021 gcatgcggct gtgaggagaa cttgttcact cacatttcgt tttcccctca acctgcaata
     4081 gcgaagccca tgcagctgtt ttgaatctgc aaagcttcgc tctatttttt cttttctttt
     4141 tttgtagagg ttttttcctg aaacagacaa gcgattttgt ctgatctttt ctttatgatc
     4201 ttcccataca tgtcgagtaa tcactttctg ccgattcttt gattttgtac agttttcaag
     4261 cagtgggcat gaggaacata tttcaggatt tgatttatat gaccggtagc cttttcggtc
     4321 agttgttgag tatgtaagtg tttggtgatt tggacaaatg tatctgtctt gttcactgtc
     4381 ataatgaaat ttccattttg gaaacaagcc tcggataggg tgataacgtc tatgtgcgat
     4441 gacaccaaag atttggcggt cagataatcc tttacagatc ggagtcgtta aatatccgga
     4501 atcaagggcg acggcttcta cttgaaaacc aaatcgtgcg atttggtggt ctaatcggtc
     4561 aagataaggc acagaatcat ggacatttcc aggtgtgacg taggcatcgg tgataatgtt
     4621 gtatttcata tctgttgtgc ggtgatctaa atagaaaaaa ccttctggtt tgttttcacg
     4681 atacagatag ccactttccg gatcggttgt actgtggcgg atctcttttt cagctttcac
     4741 ctcctctttg gctgttaatg gcttttttcc gtgttcctcc cgatcctctt gaatggcttc
     4801 atttaaatcc ttgatatagt tttgggtatc ctgcgcaatt gtttttcttg tgtatttatg
     4861 cttgttggca ttggctttaa ggtgtgtgga gtcggtgaat aggactcgtc cgcccaccat
     4921 gtcatgattg atggcctgaa gaacgatctc atcaaaaatg tcttggaaga tggtcgtatc
     4981 tttaaagcgt gtgcgtctgt tccagctgat ggtggagtgg tgtggaaccg ggtcgtttat
     5041 gttcaatccg agaaaccatc tgtacgccat attgtagtaa atttcttttt caagctgtct
     5101 ttctgaacgg ataccataga ggtatccgat aaacatcatt ttaaataaaa taagcggatc
     5161 aagtgagggg cggcctttgt tttcactgta gtaaggtttc accttttcaa tgatgaaaga
     5221 gaagtctatg tgtttatcaa ttttccgaag caggtgatcc tcttcaacga gttggtcaag
     5281 cagaacaaat tcggctgtgt tttgagaaga gtttcttgtg tggaacatga gaaagacacc
     5341 gtccttttaa gtctttcttt tattttatta cagaagaatg gatattttaa ggaaaaataa
     5401 aggctgtcga gattttctcg acagcctgac aaggacaccg ctgtccttgt ttttttcagt
     5461 caatattgca aatctccagc gggcaatttt cacactcaat ctcacatcgt aaatagtccc
     5521 gcttgtgcaa aataattttt ccggattcgt ctatcgaaat aacccctttt ttgcggagat
     5581 ctccgagcat acgattgacg ctttcccgtg cagccgcgca aaactttgcc aaatcctgat
     5641 ttgtcaggac aatgttaatc agaatgccgt cgcttcgctc cactccgtag ctgtttgata
     5701 aacggataag ggtagaatag agcgccccct ttttgccatg aagaagcaga tccctgattt
     5761 tggactgaat cttccggagg tgcgtgctca tccatttcat gaactcaaat gtcaaagcgc
     5821 cgttttggat taattctttt tccagcttat ttttattaat gacgagcacc tcgccatcct
     5881 ctagcacttt tgcactgagc atataccttg gttcttcagt gaaaagtgtt aattctccga
     5941 cgatatcatg cttttggcag attctaagcg tcaggtcttt tccatcagat gtcagcttgc
     6001 cgatttcaat gagtcctgat tgaatcagat aaagctcttc tgcatccatg ccttcccgaa
     6061 acaaatacgt gtgtttttcc atttttcttt tcgtgctgat cgattccagc aattcataca
     6121 gatcgctgga tataagatca ctatcagatg gtcgaacaga gagaaaattc atgagctcac
     6181 ctcgaagaaa gtcacgttgt gtgtttattg taacgtgaat tgatttgtac ccatcgagaa
     6241 aaaactaaca atcttgtgaa tgcccagtgt tagttgatgc tctggctgtt tctctccgtg
     6301 tgtgttttca ttctttcctg ccaatacatc catatgacaa ggacaaaact ggctaacgcc
     6361 acctctgaaa gcgccataaa cccgatcgcg tactggcctg ttgcctgaaa cacactcgcc
     6421 aatatgagcg gaggaaaaaa gccgcctaat ccgcccatgg cagacacaat cccattagca
     6481 atccccgctt gctttgaaaa atagaaaggc accagtttaa aaacagtccc gtttcctatt
     6541 cctgagcaga cggccacggt taatgatcca aacgtataaa ggccaattgt cggcgagaac
     6601 gataggataa tgcctgataa tgtaagcccg gcaaaaacaa acatcaagat gcggagcggg
     6661 ctcattttat cagccaggaa tccgcccgca ggcctgagca gcgtagaaac cgcaataaag
     6721 ccagccgtcc gcaagccggc atctgcagga ttcagcccaa aatgctccac cagaaagttc
     6781 ggcagataga tagtgaaggc gacaaaggca ccgaacgtaa taaaataaaa caggctcaga
     6841 aaccatagca catgatttcg gtaaacggct ttgatttgag tcttaacaga aactttgacc
     6901 ttcttctcat gcctgtcgcc aaacaaaacg tgcagtaagg caaagacagc tagcaaaacc
     6961 aaatacatct gcacggttga tttccacccg acggcttgag cgataaccgg cgctgcaaat
     7021 gtcgtaacgg ctgtcccgat atttcctgca ccgtaaatcc cattgacgac accgtgcttt
     7081 tctttcggat aatatttcgg gagggaggtc accccaatgg aaaacaccgc tcccccgatc
     7141 cctaagaaaa agccgcctgc gattaaatca aacagagaat ccgcgatact gatccaaaat
     7201 acaggaaata aaagcaggat gaagctgacc ataaacatga gccgcgcgcc aaacctgttc
     7261 gttaaatacc ctaaaggaat gcggagaagc gacccgagga tcacaggaat cgcggtcact
     7321 aaagaaatct cgcccttgct taaatgaata tctaatgtga tttgggaaat gagtgatgaa
     7381 atcagcaccc aaaccataaa ccctgccacc aagcttaatg actgtaacga taattgaatg
     7441 tgttgacggt tgatcatttg gcttgcccct ttcaatgatt caataatcag tcttatcata
     7501 caaaaactcg gcaaacagga ttgtgaatta catcacacgt ttttctcata aaaaaaggac
     7561 aaagcccgaa gactttgtcc ttttgttcgt gattacattt tttccggagc cgatacgccg
     7621 atcagctgaa gcgcattgtt cagcgtaatt tgcgttgcct tcattaaagc caggcgcgcg
     7681 cggcttttct cttcattttc agggtcgatg actttctctg cgttgtagaa gctgtgcaga
     7741 gcagaagcca gatcataaat atagtttgtg acacggtgcg gaattcgctt ttccgctgct
     7801 tccgccactg cctctgggaa gccgccgatc gttttcagca gatcgtattc tttttctgat
     7861 tgaatatggc tgaaatcaag atctgccgcc ggtttaagtc cctgctcttc cccttggcga
     7921 agcatgctgc aaatacgggc atgcgcgtat tgtgcataat acacagggtt ttcgttagat
     7981 gttgatacag caagatctaa gtcaaaatcc atatgggtgt ccgcacttcg catcgcaaag
     8041 aagtaacgaa cggcatccaa gccgacttct tctatcaggt cacgcatcgt tacggcttta
     8101 ccggtccgtt tgctcatttt cattttctcg ccgtttttgt aaaggtgaac gagctgaatg
     8161 atttctactt caagcgttcc tttttcatag cccagcgctt cgattgccgc tttcatacgc
     8221 gggatgtagc cgtggtgatc ggcgccccaa acgttgatca gcttatcaaa gccgcggtca
     8281 agcttgtcct tatgatacgc gatatcagga agcaggtacg tgtacgtgcc gtccttcttg
     8341 atcaatacgc ggtctttatc atcgccaaac gtcgtggaac ggaaccaagt cgcgccgtct
     8401 tcttcataga catggccttt ttcgcggagc gcttcaagcg ccttgtcgat ttttccattt
     8461 tggtacagtg aagtttctga ataccacaca tcaaacggca cacggaagtt ttccaagtcc
     8521 ttgcgaagct tttccagctc atatttcagg ccgtattcac ggaaaaacgc gaggcgttca
     8581 ctttcttctt cgttaacgaa acgatcaccg tattcctcag cgagacgctt tccgatcgca
     8641 atgatatcct cgccgcggta gccatcctcc ggcatcggtt tttccaatcc gagtgcttca
     8701 aagtaacgga cttcaacaga aagcgccaga ttgttgattt ggttacccgc atcgttaatg
     8761 tagtattcgc ggcttacatc gtaacccgct tttgaaagca cgttgcacaa ggaatcgccg
     8821 acagccgccc cgcgcgcatg cccgaggtga aggtctcccg tcggattcgc tgatacgaat
     8881 tctacctgaa ctcgttcacc gtttccgatg ttcgtttccc cgtatgcttc ccctgcttcc
     8941 agtacagacg gaatcagctt tgttaaatat tgattgttca tatagaaatt gataaaaccc
     9001 gggccggcga tatccagttt ttcaatcgaa gcctttcctt tatcaaaatg ggcgacaatc
     9061 tcttcagcga tttggcgcgg cgcttttttt gccactcttg ccagctgcat cgccatattc
     9121 gttgagtagt cgccgtgtgt tttatctttc ggtgtttcta aaacaacatt gggaatctgg
     9181 ctttcttcag ccagtcccgc tttcagaacg gccgctttga tttcttcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtgag ttcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctc ctgctcgtct ccgacatgca tgtcatatgc gatgctgata cggccttttt
     9361 cttcatcgag atcagattga atcgattttg tgcttgtttt cagctcaagc tcaccaaatg
     9421 acattttata tttagcaatt gtggaagctc cctttacgaa acgctgattc attttgacag
     9481 cgcctgacct catgaccagg acttcgcctt cgcttacttt cacaatcgtt ttgactttgc
     9541 ctaagtcgtg ttcttcataa taagatagat acactttatt ttgttttaca tagtaaaatc
     9601 cggtggtgcg gaattcgatg acttcttggt ttccgtcatc ctcgatcaca gacttcacat
     9661 ggagtgttat cggtgtctct tgcttcattc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc ggtttgtaaa cttcaactgt ttctatctta ccatcattgc
     9781 tcatcagatt tgaagataaa cctcataaaa agcatttcct tatatagaag agaaaatcat
     9841 atcactaatt acctttagga aatgttacat ttttccgaaa tctatcattt ccttttcaca
     9901 tttttttcaa aatatatgta ttgaattagt aatttgatag ttttaagata aaagtacaac
     9961 atagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaggatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtta cctcttggat atacatacac
    10201 aaccgttttt catttgaatc atatgtatag gggatggtat tttgtttata gagcagatgt
    10261 ttccatttat taatgaaagt gtaagagttc accagcttcc tgagggcggc gtgttagaaa
    10321 tcgactactt gcgcgataat gtctccattt ctgactttga gtatttggat ctcaacaaaa
    10381 cggcttacga gctctgcatg cgcatggatg gccaaaaaac agctgagcag attttagctg
    10441 agcaatgtgc agtgtatgat gaatcaccgg aagaccataa agattggtat tacgacatgc
    10501 tcaacatgct ccagaacaag caggtgatcc agcttggaaa ccgggccagc cgccatacaa
    10561 tcaccacgag cggaagcaat gaatttccga tgcccctgca cgccaccttt gaactgacgc
    10621 accgctgtaa tttgaaatgc gcccactgtt atttggaaag ctcacctgaa gcgctcggca
    10681 ccgtgtcgat tgagcaattc aaaaaaacgg ctgatatgct gtttgataac ggtgtattga
    10741 catgcgaaat cacaggcgga gaaatttttg tccatccaaa cgccaatgag attcttgact
    10801 atgtgtgtaa aaagttcaaa aaagtcgctg tcttaacaaa cggaacactc atgcgaaaag
    10861 agagcctgga gcttttgaag acttacaagc aaaaaatcat cgtcggcatt tctcttgata
    10921 gtgtcaattc cgaggtccat gactccttta gagggagaaa aggctctttt gcccaaactt
    10981 gtaaaacgat aaaattgttg agtgaccacg gtatatttgt cagagtcgcc atgtctgtct
    11041 tcgaaaaaaa catgtgggaa atccacgata tggcccaaaa ggttcgggat ctcggggcga
    11101 aggcattttc ttacaattgg gttgacgatt tcggaagagg cagggatatt gtccatccaa
    11161 cgaaagacgc cgagcagcac cgcaagttta tggaatacga gcaaaatgtg attgatgagt
    11221 ttaaagatct gattccgatt attccctatg agagaaaacg cgcggcaaat tgcggcgctg
    11281 gctggaagtc cattgtgatc agcccgttcg gcgaagtacg tccttgcgcc ctctttccaa
    11341 aggaattttc attgggaaat atttttcatg attcctatga aagcatcttt aactcccctc
    11401 tcgtccataa actgtggcaa gcgcaggcgc cgcgcttcag tgaacattgc atgaaagaca
    11461 aatgcccgtt cagcggctat tgcggaggct gttacttaaa agggctgaac tctaacaaat
    11521 atcaccgaaa aaacatttgc tcttgggcga aaaatgaaca attagaagac gtggtccagc
    11581 ttatttagga gggaaacgat ttgtcaccag cacaaagaag aattttactg tatatccttt
    11641 catttatctt tgtcatcggc gcagtcgtct attttgtcaa aagcgattat ctgtttacgc
    11701 tgattttcat tgccattgcc attctgttcg ggatgcgcgc gcggaaggct gactcgcgat
    11761 gagcattttg gatatacacg atgtatccgt ttggtatgaa cgggacaacg tcatcttaga
    11821 acaagtagat ttacatttag aaaaaggcgc cgtttacggg ttgcttgggg taaacggcgc
    11881 cggaaaaacg acactgatta atacgctgac aggcgtgaac cgcaatttca gcgggcgctt
    11941 tacactgtgc ggaattgaag cggaggccgg catgccgcag aaaacatcag atcagctgaa
    12001 gactcaccgt tacttcgccg ccgattatcc gctgctattt acagaaatta cggcgaagga
    12061 ctatgtgtct ttcgtccatt cgctttatca aaaggatttt tcagagcagc agtttgccag
    12121 tttggccgag gcctttcatt tttcgaaata catcaacagg agaatttcgg agctgtcctt
    12181 ggggaacagg caaaaggttg tattgatgac aggcttattg ctgcgcgctc ccctatttat
    12241 tttggatgag ccgctcgtcg gtttggatgt ggaatcgata gaggtctttt atcagaaaac
    12301 gcgcgagtac tgtgaagcag gcgggaccat tttgttttct tctcatctgc tcgatgtcgt
    12361 gcaaagattt tgtgattacg cggctattct tgacaacaaa cagatccaaa aggtcattcc
    12421 gattggagag gagaccgatc tgcggcggga atttttcgag gtgatcggcc atgaataaca
    12481 taatccccat catgtctttg ctgttcaaac agctttacag ccggcaaggg aaaaaggacg
    12541 ccatccgcat tgccgcaggc cttgtcattc tggccgtgtt tgaaatcggg ctgattcgcc
    12601 aggccggcat tgatgaatcg gtgttgcgca aaacgtatat catactcgcg cttctcttaa
    12661 tgaacgcata tatggtgttt ctttctgtga catctcaatg gaaggaatct tatatgaaac
    12721 tgagctgcct gctgccgatt tcttcacgga gcttttggct cgcccagagt gtcgttttgt
    12781 ttgtcgatac ctgtttgaga agaactttat tcttttttat tttaccgctg ttcttatttg
    12841 gaaacggaac gctgtcaggg gcgcaaacat tgttttggct cggcaggttt tcgtttttta
    12901 ccgtttactc cattattttc ggagttgtgc taagcaacca cttcgtcaaa aagaagaact
    12961 tgatgtttct gctgcatgcg gcgatattcg cctgtgtatg tatcagcgcc gctttgatgc
    13021 cggccgccac gcttccgctt tgcgcggtgc atatgctgtg ggcggtgatc attgactttc
    13081 ctgtctttct gcaggcgcct ccgcagcaga gcaagatgca ttcatttatg cggcgatctg
    13141 aattttcgtt ttacaaaaga gaatggaacc gatttatctc ttctaaagcg atgctgttaa
    13201 attacgcggt aatggcggcg ttcagcggct tcttttcgtt ccagatgatg aataccggca
    13261 tcttcaatca gcaagtggtt tatatcgtga tttccgcgct tttgctcatc tgctcgccga
    13321 tcgccctttt gtattcgatt gaaaaaaatg accggatgct gcttatcacg cttccgatca
    13381 agcggaaaac gatgttttgg gcgaaatatc gcttttattc aggcctattg gcaggcggat
    13441 ttctccttgt cgtgatgatt gtgggtttca tcagcggccg tccgatttca gttctcactt
    13501 ttttgcagtg cattgagttg ctgctggcgg gagcttttat caggttaact gcggatgaaa
    13561 aaaggccctc cttcagctgg cagacggagc agcagctatg gagcggtttc tcaaaatatc
    13621 ggtcttatct gttttgtctt cccctattct tagccacatt agccggcacc gctgtatcct
    13681 tggcggtcat tccgatagcc ggtctggtca tagtctatta cctgcaaaaa caggatggtg
    13741 gtttctttga tacaagcaaa agagaacggc ttggaagtta acctgctgaa gactcatcaa
    13801 ttttcaacta tttcaatcgc cgcgagcttt ctgaaaccga tcgaaagcgc ggcggaacct
    13861 gaggaagaaa cgatttattt ttacggcgcc gccgcatacc tgaaggagca aattattgac
    13921 gctttcggtt gtgctgccgg cagccgtttc atgtactcag cgaatctctt ttttgatcag
    13981 cagctgaaaa cctgcgggac ccgtttgatt cacccattat ataacgggaa tcttcatgtt
    14041 gacgccctgc tgaaaacttt tgcagacttg tctttccctt cttctctttc attcgaagca
    14101 gttgaaaagg ccaggaatga gctgctgctg agaatcgaaa agaaattcac tgatcctttc
    14161 tcctactcgg cggcgcgctt ggctgaggag gtcttcggaa acccgatgta cggcacaggc
    14221 atgtttggcc ggaaagacag gataaaggcg attcatccta aacggtttct cgacgcaacg
    14281 gactttatcg ttgatttagt gtcccagcaa aaacagctga acatattggg acaagtacaa
    14341 gcatgtgatg ttcggggaca tgccccgcaa acgtccgctg taacgtccga aagaataccc
    14401 gtaaaccggc atgtttttga aacagagaca cgcagcgctg caggtccttc cgtcttgaca
    14461 ctcggatttg actgcggaga gatgaaagat gccagcgatt atatcaaaat acagctaata
    14521 gacggattac tgggaaagta cggccattcc gctttattca agcacttcag agagaaggat
    14581 ctggcagtct atcacgttat cacccgttac gatgtcatga acaatttgct gcttgtttca
    14641 atatgtacag atcagcttca tgagatagac attcccccgc gcgttttgga agctgtctca
    14701 gcttttcata cagatgagcg ggaactagaa caggcaaagc agtttttacg caatgaattg
    14761 ctgctgcaat tcgattctcc cgaaggtcta ttggcctata tggggatcct gcgccgcttc
    14821 tcctgcacga aagaagcctt gctggatggc atctcagcgg ttacatgccg tgatgtattg
    14881 caattcatag cgaccatcaa ttatatcgga gctcatgtag taaggggatg aagagatgga
    14941 aaagaaagcc ttttttcaac aactggatga acgaaccgat atcagataca cagacagcgg
    15001 actaaaaata ttcagattga aattcccccg cgcccacctg cggctgtgca atgtaaaaat
    15061 cgattttgga agccgggatg tatgtatacg ggcagaatcc ggtgatacac tgcttccgta
    15121 tggcacagcg cattttttag agcatcttct cttctggcat aacggccgca atctgtacag
    15181 tgattttttt gcgcatggcg cgcttttaaa cgcattcact acctacaccg ataccaattt
    15241 catgtttacc tcattaccgg atcggctcag acaaacgatc cccatcctgc ttgatgcttt
    15301 atggaaccac tcatttgaca agaagattgt cgctcaggaa aaagctgtga ttacaagcga
    15361 aattcaaaca gcacacctta acgatcagct ctcatatcat tatcagctga tcagcatgct
    15421 ttctccctcc tcaccagctg ccgttttccc cgcaggcaga atcgaagata ttgaggcgct
    15481 ggacatcagt gatttacaaa aagcctataa ggctgcctac caaacccatc ggatgacgct
    15541 gtttttgatt gggggctcag aaaatacaga aacgcttttg cctcctcacc tccagctgga
    15601 aaagcgtccg gattatcatg ctgaaagaaa aatcatcccg gcatgccctc cagccctctc
    15661 acaaaaaatg atgctgggtg atgaggagcg gatggaagat acatggaccg gattacagat
    15721 cggcgcactt cccgggcaaa acgatctgtg ggtgataaag ctttattggg atatcgcggc
    15781 tcgtattcta tttcaattag attcaccgtt ttttcaagag attcagcaaa cgtaccgtct
    15841 ggaaatcgat cgcttgtcag ccgagactta tatatatgag gatggcggtt tcttgatcct
    15901 tcacagtcaa gggacccatt cttcagctta tatcgatgtg gcttcatact atgtcacaca
    15961 gaagaaagaa caggttgccg cctggcttca atacggcaag gactctttga cagacgcgat
    16021 catttatgac agcgattatg tgcgtaaatg cttcgagtgg gcagccgagt gtgacaggtg
    16081 cgattgctcg tttcttgaca tgtaccacat cattcaagat atggatgcgc aggttttctt
    16141 gtctctcatt gatgcaatgg catcttctaa caaagcgatc attcacgttt ctcagaaaga
    16201 ggcgatcaga caatgaaaaa aagcactgtc tttacccttt tattgctgct tataggtatg
    16261 gcggcttatt ccttcggatg ggttcaggcc gttgccgaag ccgccgccca atatgtacag
    16321 atgatcaaca atgatgctgt tcggctcgga ctgctggctt gtaccgctgc cctcctgatg
    16381 ctgcctgctt ttctatatct tcattatgtc acccaatccg tgaaaaacat gacagcagct
    16441 tttcagaaac tcacacagtc tcatcaaagc tgctgtgact ttcagcaaca caacttgtgc
    16501 agccgatatg cagaagacgt caaatcgctg cgtgacagct ataaaaacgt ccgccaaaca
    16561 tacgtgatgg ctgccgtgtt gtgccaagtc atcatattcg gctgcatgtt cgaaatcgtt
    16621 aaagccgtcc ctttccgcct tcacacgccc cctgcccttt caatgggact tgcgatgcta
    16681 ctgattctgt atttattgtt ttgcatgcga acttatttgc ggcagctttt ccggcacggc
    16741 agcctgttca gaaaagtgtt tgcgggagcg ctggcagcag ccgggatttg gtggatgctc
    16801 agtttctcta taagtgaact gctgtttctg attatcctgg ctaccattca gcaaatcgga
    16861 tcatttattt ataaacgatt ctcttatcgc agcaccgctt ctcttgatct ataaaatagc
    16921 tacatcgcaa tcgcagacgg acccgcgcca accggaatca ccgtcacggc tgtataatca
    16981 cttgtgcggt acacggtcac agcattgtcg ttgggctgtg ccgcataaat atactgtttg
    17041 tccggcgtta cggcgaggtc aaaagcgccg gggagagaca cgtttgcaat gatcctctgt
    17101 ctggccgtat taactacata taagttatta ataagaaacg gttcactata tggctctaga
    17161 aaataagctc tagtgctatc gagagaaaat acaatcgtcc tcagcgtttc aaataaacgg
    17221 ctgaagtccc ctcccctgct taatggagac aaactaatct ccgttacacc tttcggccac
    17281 agctcaccat tcaacacgta cgcaaaattt ccagcgtaag gagttgcaat taaactggga
    17341 aattcaaatg tatctatgat actttctacc aactgcccag tatttatatc atatttatca
    17401 accgaccaac tgcttccatt agcggtatag acatactgtc cattcggatc aagagcaaag
    17461 tctaaagcgc cgggtatcgg aatgacatca atgaccgatt gagaggccgt gttaatcaca
    17521 tatatagatc cggcggccat cacgtacgcg aactcatctt ttggatcaaa ttcgatcttt
    17581 ctcggccctc ctccaacagt aatggtattt atgatggtta atgttttatt atcaatcact
    17641 gagacaaggt tggtatttcc atggaggaca tacgtgaatg ctttatcgaa agtaacgcct
    17701 agattagttg gcacgtcaga aaaagggatt gtttttacaa cagtgtttaa atctgcatca
    17761 ataaccgaaa ccgtgctgtc tccagtattg gcagtaaaca catacgattg agggtctggt
    17821 gatggcggta aaacaagtgt cccggtcacc gtaagcggac tgccgtagaa aggcggtaca
    17881 atgagcagat cttccactgt tatttgactg aaatcaggac agcggccaga ctgcgctgca
    17941 taataaacaa cttgatcaat ctcttcggta tgaatcacag aaaccgcccc attgccttgt
    18001 ccatattgat ttcgcacagg cgacacactg acaagaagcg taatggtccc ttgtactctc
    18061 acagcatatc gaacaccgat atcttctggt tccggcccag tctggattaa gcaaggctca
    18121 ctgatacagg acacattgtc tgtactccat gtaacagccg ctgacgcttc ggccgaatca
    18181 accttgaagc cctcagggat atctatcggc acttgaaacg gcgcttctcg gctaatttcc
    18241 tcatcacaaa aacagaaaca attttcctgt aaagcagaaa gatccattct ttttcatgat
    18301 ttcacgtcct tttagaaatg cacaacatgc agcggttaaa tcgtaatggc acccggtgaa
    18361 accccaagag atatcacagt ctccacggag taatcatccg tgttgtaaac agtgatgctc
    18421 tgttctagaa catgagttgc atacagaaat tcgccattcg gggtaaacgc aaagtctctt
    18481 gccgactgcg gaacatttcc tataacgcct gctccatttg gactgacaga atataaattg
    18541 ccagtgaagc cgtcatataa atacacctct gctccactcg taaacattcg atattcccct
    18601 tcatactcca gctcttgggt actgctgatg gcaaacgtat ttaaatcaat aaccgtcaaa
    18661 taattaaaaa agaattcttg ttctaataca taggcatacc gctccggcca atttgtttct
    18721 atggttgata cgataagctc tcgttcaatt gttcctgtga cttcaccggt agttaggtcc
    18781 actttttgca ctataccaaa atttagaaca taggcgaata acccattggg atcgattgca
    18841 acatcatacc cttccacagg aatcgaccta tccacagtta acgtatcaat tccaatcaca
    18901 gaaaccgcag taccggtgaa aacataagca aactcatgat tagggataaa tctaatcaat
    18961 cgaggcggct gatccagcaa tatagatgct gtcactgtta atgtgtcata atcgatgaca
    19021 gaaatcacat tattgttggg atgtgagaca aacacagcgc ttttatccgg ggtaatttca
    19081 atacctgccg gattgtacgg aagagcaatc gttgtcacaa tagaatgagt gtttgtatca
    19141 atcacagaaa ctgattgatc atttgaattc gctgtaaacg cgtaaacggg ttccggctcc
    19201 ggtacaagca caatcgtccc cgtcaccgat aaaggactgc cgtaaaacgg cggaacaaca
    19261 acaaggttct caatcgtgat gtcactgata tccgggcaat catccggttc atcggaataa
    19321 tagacgactt gatcgatctc tgcattgtga atgacggaaa cagccccgtc cccttgtcca
    19381 tattgatttc gcacaggtga gacactgacg agtagcgtaa cggttccctg caggcgcact
    19441 gcaaattgaa caccgacctc atcaggctca ggccccgttt gaattaagca acggtcactg
    19501 acacaagaaa ggctgtctgc attccacgtc acgtttgcaa cagcttcagc cggatcaacg
    19561 acaaaccctt caggtaattc aatcggtgct tgaaacatgg cttctcggct tgcttctccc
    19621 tcacaaaaac ataagcactc ttcttgttct gctcctgctt tttctttaaa ggaaagcttg
    19681 ttttttctca ttccttcact tccttttcag acatacactg ctcacgcaga tataacagaa
    19741 tatggaaggg taacgtgttt gcttgtacaa attgctgagg gtaaaagctt ctttttgaaa
    19801 atatatctcc aaacatgcgg tgtaacgaaa gaaaaaattg cggttttttt gcgcttctca
    19861 caagaatgtt gatgataaaa tatgacatat atagaattat gaagggaggg atttgcaaac
    19921 gtgtcaggtg tcatatcttc ttcttccatc ggagaaaaga ttaacgaatg gtatatgtac
    19981 atacgccgat tcagcatacc cgatgcagaa tatttgcgac gagaaatcaa gcaagagctg
    20041 gatcaaatgg aagaagatca agaccttcat ttgtactatt cactaatgga gtttcggcac
    20101 aacctgatgc ttgagtacct tgaaccgtta gaaaaaatga ggattgagga acagccgaga
    20161 ctgtctgatc tgctgcttga gattgataaa aaacaggctc gtttaactgg tctgcttgag
    20221 tactatttta atttcttcag aggcatgtat gagctggatc gccgtgaata tgtattagcc
    20281 attcaattct ttaaaaaagc tgagagcaag ctggtttttg tgaaagataa aatcgataaa
    20341 gctgaattct ttttcaaaat gtcagaagtc tattattata tgaaacaaac ttatgtctcc
    20401 atggactatg cacgtcaagc attcgaaata tacagtgaac agactacata tgatatcaga
    20461 atgattcaat gccagtcctt attcggagcc aactttttgg atttaaaaca atacgaaaaa
    20521 gcaattgccc attttcaaaa agcctttaca cttgcaaaaa cagagcagca gccccaatta
    20581 atgggaagaa cactttataa catagcactc tgcaagcaaa accaaaacag ttttgaatca
    20641 gcgatagagt atgtaaaaaa atctattcaa gtatttgaag gatctaaaat gcttccttca
    20701 ttgccacaag cttttttcct aattacacaa atttatttta aattaggtaa gattgataac
    20761 gcctgtgaat atcataaaaa aggaaaagag tattctgcag ctgcgggaga taccgtgtat
    20821 ctaacggagt ttgaattttt ggaatcttta tacttgtctg gaccggatga ggaacggata
    20881 gaaaaatgtt ttgtttttct tgaaagtaaa atgatgtatg cagatattga ggacttcgca
    20941 cttgatgttg ctaaatatta tcatcaacag gaaaattaca aaaaagcatc tcattacttt
    21001 ttaaaggttg aagaagcaag acagcacatt caaggggggg tgaatttata tgaaatggaa
    21061 gtataaatta ttactcgctt gtttagctgt gagtgctgta tttatcacag tcgaagtatc
    21121 aaattcatca acagaacatt ttgatgttgc gcaacgcgcc atgatctaaa ccgccgtcca
    21181 tcggcggttt ttttgtcccc tctttaccaa agtcccccaa tccacgctat gatcttttca
    21241 ataatcttga agagagtgga aatgcagcat gtctctggaa agtgtgaaaa cccactttac
    21301 acagtggaat ggagaaaatg atgtgacgga gttcgaaacg tcgagcgcga cagtgttgaa
    21361 cagacagctg agacgatcgg cgtaagcccg actagaatcg ccaagaccct gtccttcaga
    21421 ggggaaggag atcaggcgat tctgattgtg gcagccggcg atgccaagat taataacaaa
    21481 aagttcaggc aaacatttgg ctttaaagca agagtgctct ctcctaatga ggtactggag
    21541 cagacaggcc atgaaattgg aggtgtttgc ccatttgggt tggctcat
//
