LOCUS       NZ_CP102415            24194 bp    DNA     circular CON 26-AUG-2024
DEFINITION  Amycolatopsis roodepoortensis strain ZEL-1 chromosome, complete
            genome.
ACCESSION   NZ_CP102415
VERSION     NZ_CP102415.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis roodepoortensis
  ORGANISM  Amycolatopsis roodepoortensis
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 9489959)
  AUTHORS   Gao,T., Li,J., Ni,W., Xiong,S., Qiu,H., Li,W., Xia,W., Tao,X.,
            He,X., Yong,B., Wu,B. and Shao,H.
  TITLE     Biodegradation of petroleum hydrocarbons by Amycolatopsis orientalis
            ZEL-1, genome analysis and its potential in plant protection
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9489959)
  AUTHORS   Gao,T., Li,J., Ni,W., Xiong,S., Qiu,H., Li,W., Xia,W., Tao,X.,
            He,X., Yong,B., Wu,B. and Shao,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2022) College of Life Sciences, Sichuan Normal
            University, No. 1819, Section 2, Chenglong Avenue, Longquan
            District, Chengdu 610101, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. 0.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024628825.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 06:13:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,064
            CDSs (total)                      :: 8,994
            Genes (coding)                    :: 8,928
            CDSs (with protein)               :: 8,928
            Genes (RNA)                       :: 70
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 27 of 66
            Pseudo Genes (incomplete)         :: 44 of 66
            Pseudo Genes (internal stop)      :: 4 of 66
            Pseudo Genes (multiple problems)  :: 9 of 66
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:48:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1288685
            Orig. end                         :: 1312879
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102415.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24194
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24194
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24194
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14194](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14194
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(565..580)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.72"
                     /tool="antismash"
     misc_feature    1111..1125
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     misc_feature    2466..2480
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.84"
                     /tool="antismash"
     misc_feature    2492..2505
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.25"
                     /tool="antismash"
     gene            complement(2569..3294)
                     /locus_tag="NQK81_RS06070"
                     /old_locus_tag="NQK81_06070"
     CDS             complement(2569..3294)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (93-220). E-value:
                     1.8e-13. Score: 43.1. Matches aSDomain:
                     nrpspksdomains_NQK81_RS06070_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022072.5"
                     /locus_tag="NQK81_RS06070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06070"
                     /product="SRPBCC family protein"
                     /protein_id="WP_257487420.1"
                     /transl_table=11
                     /translation="MGEQWWWGAIGAVMVVGGLLMRRPSDRKWRSFAVGIVTSAGWMLV
                     ALFVIAPLIPANVLGITILIVIVLGVLAVPLIVRLGAVSRTSRGVPGRMTEYRHTATIE
                     MPAADLFAYLREPRNLPRYFPRMSRAEPEGGEAVHVEADVHGEHVEGEAWLKVDEANRS
                     LRWGAQGPHDYQGELSIEDAGPAASRLTVTLHSVRDADDEDVQRGLEETVAALAHTVTA
                     DADVDAAEKEGGWAGHRDS"
     aSDomain        complement(2635..3015)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NQK81_RS06070_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.80E-13"
                     /label="NQK81_RS06070_Polyketide_cyc2.1"
                     /locus_tag="NQK81_RS06070"
                     /protein_end="220"
                     /protein_start="93"
                     /score="43.1"
                     /tool="antismash"
                     /translation="MTEYRHTATIEMPAADLFAYLREPRNLPRYFPRMSRAEPEGGEAV
                     HVEADVHGEHVEGEAWLKVDEANRSLRWGAQGPHDYQGELSIEDAGPAASRLTVTLHSV
                     RDADDEDVQRGLEETVAALAHTV"
     gene            complement(3324..4193)
                     /locus_tag="NQK81_RS06075"
                     /old_locus_tag="NQK81_06075"
     CDS             complement(3324..4193)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334991.1"
                     /locus_tag="NQK81_RS06075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06075"
                     /product="sucrase ferredoxin"
                     /protein_id="WP_257487421.1"
                     /transl_table=11
                     /translation="MTAAQRCAELAEAAGDPGEGTAPPAEHWLLIEHPGPWGRFALKES
                     GIDPAAVAHLGSWAARVGGRIALVRRVARRPSTRDRPFRWFRVDARPGHEQIRTGEFTD
                     AAELSRVTSAAGSVWPEPLALVCVHGRHDTCCAVRGRSLATALAAEFPGATWECSHLGG
                     CRFAPSMVLLPHGFTFGGLRPDDAIGLYHQYVDGILDPRFLRGRSSYPPIVQAAHHHAR
                     AATGAAGIDDLRLTKTTRAGDTWQVGFAEPDCTVYLREGRIPAGRRLTCASEPVRTIRV
                     FELVDLRY"
     gene            complement(4190..5473)
                     /locus_tag="NQK81_RS06080"
                     /old_locus_tag="NQK81_06080"
     CDS             complement(4190..5473)
                     /EC_number="1.14.11.47"
                     /GO_process="GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020500226.1"
                     /locus_tag="NQK81_RS06080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06080"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_257487422.1"
                     /transl_table=11
                     /translation="MARAELSGPSTGSGESVPEPVDGHVPTSVLSRLVGSDVAEFATRH
                     WGREPLLRRTGGDFGDLLDLDGVDEMLSRRGLRTPFLRLARDGAVVDSRSFTGGAGVGA
                     EIGDQVRDDRVAALFAEGSTIVLQGLHRIWPAIIDFTTRLTGELGHPAQVNAYITPPSS
                     QGFSAHYDVHDVFVLQAAGRKRWKVHAPVHPSPLRDQPWGEHADAVAGRARDDAPVIDE
                     VLAPGDVLYLPRGWLHSATALGDVSAHLTVGVHVITAFALVEALTALAGSEERLRKSLP
                     LGIDVADPSLLEAHVESVREDLIAALRAVPGDAVARHVRDRTWRGNRPEPLAPIATARF
                     VLGLGDGDSVRRRDGLRFRIGGPADGRIVLELPDRRLSLPASTSTALAALLDGRTWRLG
                     EIPGMDRADQLVLVRRLLREGVLMASTA"
     gene            complement(5460..5669)
                     /locus_tag="NQK81_RS06085"
                     /old_locus_tag="NQK81_06085"
     CDS             complement(5460..5669)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334993.1"
                     /locus_tag="NQK81_RS06085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06085"
                     /product="hypothetical protein"
                     /protein_id="WP_126731016.1"
                     /transl_table=11
                     /translation="MSLNDDDISTTSGEDREGPADAGAGQGTPGEHDGGADGGAEGPAD
                     SGAGEGTAGQHDGGADGGADSGAS"
     misc_feature    complement(5686..5699)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            6005..6373
                     /locus_tag="NQK81_RS06090"
                     /old_locus_tag="NQK81_06090"
     CDS             6005..6373
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.5"
                     /locus_tag="NQK81_RS06090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06090"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_257487423.1"
                     /transl_table=11
                     /translation="MPSPHRKTPAPVLGHEHATGLLILTVTGELDASTAPLLDRHLDGN
                     LHDRTVIDLSRVTFLGVAGLQVLEAAVTRAGHERRRLALVSSSPTDLRILRLFGLDVRV
                     PVYPRLSDAIREIASQVP"
     gene            complement(6359..7582)
                     /locus_tag="NQK81_RS06095"
                     /old_locus_tag="NQK81_06095"
     CDS             complement(6359..7582)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033020.1"
                     /locus_tag="NQK81_RS06095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06095"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_257487424.1"
                     /transl_table=11
                     /translation="MPVHETEVVVIGAGLAGLSAALHLHRAGVVCTVLEAGDEVGGRVR
                     TDVVDGFRLDRGFQILNPAYPAIQRLVDVDALRLGRFWRAVRVADDDRLSLLGNPLDTP
                     KALRDVAARRYLSAKDLAALGAFTARAAGGPARSIVQGRDGTTADELRGAGLSDRAVET
                     VLRPFLSGVFLEAGLSTSSRFFRLVWRSFLRSAPSLPSLGMGELPRQLARLLPVSAVRT
                     GTRVERVGDGEVRTSGGDVWTARAVVVATDGTTAAGLVDGVPEPRWNSVTTWYFAPPRS
                     PLREPVIVVDARGGPILNTSVLSEVCPAYAPEGSALVSASALMPLGESEVRRELSRMYR
                     VDASRWPLVARYEIPRALPAMPPPHDVRGEIRFGERLYVCGDHRDTSSLQGALASGGRT
                     ARAVLRDL"
     gene            complement(7618..8631)
                     /locus_tag="NQK81_RS06100"
                     /old_locus_tag="NQK81_06100"
     CDS             complement(7618..8631)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016331951.1"
                     /locus_tag="NQK81_RS06100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06100"
                     /product="Rieske (2Fe-2S) protein"
                     /protein_id="WP_257489705.1"
                     /transl_table=11
                     /translation="MDLRRQVLERWPSNWPVQPFREPAWARQEPTYRECAPALIDAAVK
                     RADARVAGNWFVVAASREIRADKPLGLRAGGRELVAWRGPDGALTIGPGACPHLGAPLA
                     EARVHCGELVCRWHGLRVGSDRPGWTSLPSYDDGVLAWVRLDRFGGEAPTERPVVPDRP
                     LGDLAVDAVATLTGICEPMDVVANRLDPWHGAWFHPYSFTRLRVVSAPQGNEVADADDK
                     FVVEVTFRLAGKLGVPVIAEFTCPEPRTVLMTIVEGEGTGSVVETHATPLGTGPDGRPR
                     TAVIEATIATSERPGFAKAARIAPALRPLMRRASARLWRDDLAYAERRYALRAGHV"
     gene            complement(8701..9582)
                     /locus_tag="NQK81_RS06105"
                     /old_locus_tag="NQK81_06105"
     CDS             complement(8701..9582)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226309.1"
                     /locus_tag="NQK81_RS06105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06105"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_257487425.1"
                     /transl_table=11
                     /translation="MEVDEENGLRPTGSWTPGKVAEVLGISPVTLRTWATRYGVGPSLR
                     ADGRHRRYSDADVRRLQHMQRLIDRGIRAREAAAAAFSGAAAALPEVPADRRVDELERA
                     AEDLEFASIAALLDETLDSLGAAATWTDVLLPILRNLGGRWQRGDVCFESEWALTTEVS
                     LALQRYVARFATAPSERGALLSCCPDERHSLPVEILRASMVEIGIPAVYLGQMVPAETV
                     AGMASKLDPVLIVLWSMSVTTVDDLLRRRLQQQGFEVVVAGPGWEGLDVHGTPWVNDLD
                     GALEVAAERLKS"
     gene            10001..11083
                     /locus_tag="NQK81_RS06110"
                     /old_locus_tag="NQK81_06110"
     CDS             10001..11083
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016331949.1"
                     /locus_tag="NQK81_RS06110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06110"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_257487426.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.3e-42, bitscore:
                     144.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASIMAEEAPAAWLDTLGRRCLAEAYGFVEARAAEHFAGHGEGEL
                     AETVIPEFVAGGKFLRPMFAYVGWRCGGPESDAALRAAASLELLHCFALAQDDVMDGSP
                     LRRGRPALHVRFARWHTEQGWSGSADRFGESAATLSGDLFLVWSERMLRESGLDAAALA
                     RGWPRYDLMRAELAVGQLADLVNDARTLPDWETLLDVLRRKSGNYTVRRPLEFGAALAG
                     CGPDVLAALAEYGGLVGEAFQFRDDLLGVFGDPAVTGKPAGQDLRDRKASSVVVLAAEM
                     ADRRQRAELGELLAPSTVDDEAVARWRALITATGARERLGELIRERAEKAQAVIDPAVF
                     PRHAADSLAVLATKCTERDQ"
     gene            11080..12576
                     /gene="crtI"
                     /locus_tag="NQK81_RS06115"
                     /old_locus_tag="NQK81_06115"
     CDS             11080..12576
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016331948.1"
                     /locus_tag="NQK81_RS06115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06115"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_257487427.1"
                     /sec_met_domain="DAO (E-value: 4.4e-23, bitscore: 81.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTVPGPTDRVVVVGAGLSGLAAALHLAGRGRSVTVLERDPGPGG
                     RAGRVERKGYLLDTGPTVLTMPSILRDTFGAVGAELSEELPLIRLDPAYVAQFADGSTL
                     PVHTDAAAMTDAVREFAGPAEAAGYVRLREWLTRLYRTEFSRFIDSNIDSPPGMLRPEL
                     ARLVALGGFRRLDPKIGSFLSDERLKRVFTFQALYAGESPMRALALYAVISYMDTVGGV
                     YFPPGGVAALPQALARVAAANGVVFHYGDPVNALERDGGRIRAVRTAGGERHPCDAVVL
                     TTEPPESYRLLGRHPKRPVPLRPAPSALILHTGGPGEHSAIGHHTISFGQGWASTFDEL
                     ISTGRRMTDPSLLITRPTATDPGLAPPGRQLFSILAPVPNLDRGPADWTADAGPYAEEI
                     LSVARERLLPDFEPEFTEVISPADWADRGLVAGTPFGYAHSFGQTGPFRPRNFPRGTEN
                     VVLAGGGTVPGVGVPTVLISGRLAADRITGTPMRGAEANR"
     gene            12573..13535
                     /locus_tag="NQK81_RS06120"
                     /old_locus_tag="NQK81_06120"
     CDS             12573..13535
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020647222.1"
                     /locus_tag="NQK81_RS06120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06120"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_257487428.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.1e-118,
                     bitscore: 392.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.8e-61,
                     bitscore: 206.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKHELDAAGIRDPHLRAAYTWCRGLNARHGRTYFLATRMLTAPQ
                     RPAVHALYGFARWLDDIVDEPDPAATPRSLAARLSEVEGRFRADLASGTSTDPLLRAVI
                     DTAARYELEEHLFRAFLTSMRMDLSVTGYATRDDLDVYVHGSAEVIGLQVLPILGAVTH
                     REEAAPRAAALGKAFQLTNFLRDVAEDFARGRVYLPADELKVHDVDRDRLAWCAEHGRA
                     DAPVRAAIRDQIAVTRRIYAEARPGIAMLHPVSRPCVATAATLYGEILDRIEDAGHDVF
                     ARRVRVTRRRRLGVACGAFARSQWARRRHPAPAPPAAVS"
     gene            13536..13877
                     /locus_tag="NQK81_RS06125"
                     /old_locus_tag="NQK81_06125"
     CDS             13536..13877
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225922.1"
                     /locus_tag="NQK81_RS06125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06125"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_126731004.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 4.3e-20,
                     bitscore: 71.0, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKFEYLIVLAACVLVTLPLEMAGARVYRQPKRLARALLPVALVF
                     LVWDALAIAAGVWGYAPEFMTGVHAPFAIPLEEILFFVVIPICGLLTYEMVQLSLTVAR
                     RRGERAVRR"
     gene            13874..14194
                     /locus_tag="NQK81_RS06130"
                     /old_locus_tag="NQK81_06130"
     CDS             13874..14194
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016331945.1"
                     /locus_tag="NQK81_RS06130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06130"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_126731003.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 2.4e-17,
                     bitscore: 62.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPWGYTVPAVVAVVVVVLAEVVVLKTGLFRKPAYWITMAIVLGF
                     QIPVDGWLTKLSAPIVLYAPEHVTGWRFPWDIPVEDFLFGYALVTAVLLLWERSRPREE
                     AR"
     gene            14191..14922
                     /locus_tag="NQK81_RS06135"
                     /old_locus_tag="NQK81_06135"
     CDS             14191..14922
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225920.1"
                     /locus_tag="NQK81_RS06135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06135"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_257487429.1"
                     /transl_table=11
                     /translation="MNALARDGLPRDTVPSAFDTEARFYDRLVRANPGYHRHLLLSAQR
                     LDLPYDGQHLRLLDAGCGTGASTAALVAAAPGAKITAFDASREMLARARDKTWPEGVEF
                     VHTSAEELAGVEGPFDAILAAYLLRNLADPTSQLRRLRGLLRPGGRIAVHEYSVRDSRR
                     ARWVWNAVCAAVIIPLGKVVTGDATLYRHLRRSVAEFDGIGSLAHRLTDAGFTDVHTAT
                     VPGWQRDIVHTVVGTAPEETP"
     gene            14919..16487
                     /locus_tag="NQK81_RS06140"
                     /old_locus_tag="NQK81_06140"
     CDS             14919..16487
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225919.1"
                     /locus_tag="NQK81_RS06140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06140"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_257487430.1"
                     /sec_met_domain="DAO (E-value: 3.6e-09, bitscore: 35.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPLDRRLVTYPASRGLADAGQLGARPTVAVVGGGIAGLTAATG
                     LAERGVTVTVFEREDHLGGRVGGWRERLPDGTPVTMSRGFHAFFRQYYNLRTLLTRTDP
                     HSERLTPLSDYPLLDAHGRIDTFAGLPRTPIWNAAVFALRSPTFTPRDLLRLSGREALP
                     LATVSVPETYHRLDHIDASTFLEAINFPAAARHLAFEVFSRSFFADPRDLSAAELAAMF
                     HLYFLGSSEGLVFDVPTEPFPQALWDPLASYLAGRRVEIRTGAAVTALGRTPDGFEVET
                     GGRTEGFDGVVLACDIAGLRDLVTASPDLATESWRRAIGELRTAPPFLVRRLWLDRPVE
                     RRRPPFLGTGSVPPLDNISLLDRYEGEARRWAARTGGSVVELHAYAAATADQSGLEKAL
                     EQRLHEIYPETRDARVAGESTLWREDCPLFGVGDFARRPAVRTPDPLLALAGDGIRIDL
                     PVALMERAAATGWAAANTLLGHWGLAGHPLRSVPNRGRIGLLNRLAASKYVGGGRRRRT
                     GLAAG"
     gene            complement(16507..16806)
                     /locus_tag="NQK81_RS06145"
                     /old_locus_tag="NQK81_06145"
     CDS             complement(16507..16806)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334983.1"
                     /locus_tag="NQK81_RS06145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06145"
                     /product="hypothetical protein"
                     /protein_id="WP_257487431.1"
                     /transl_table=11
                     /translation="MTEPDRTPDGRFVVIGGRRWRATDPEIPEETAARLRGLLMRARRD
                     VGAARRAQDPEAEREARARVHIAKVALGERGTPWWEQDQAERRQRWQRGLDLLS"
     gene            complement(16799..17152)
                     /locus_tag="NQK81_RS06150"
                     /old_locus_tag="NQK81_06150"
     CDS             complement(16799..17152)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023056.5"
                     /locus_tag="NQK81_RS06150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06150"
                     /product="DUF3253 domain-containing protein"
                     /protein_id="WP_257487432.1"
                     /transl_table=11
                     /translation="MTSRSGPRRELERILENAGPGAVHARTALGTGPVPDRLRAAILAL
                     AFARGECGSCCPSDAARALADEWRPLLPRARELARELARAGEVRLTQGARSLDPDAEWE
                     GPIRIRLAGDADD"
     gene            complement(17190..17417)
                     /locus_tag="NQK81_RS06155"
                     /old_locus_tag="NQK81_06155"
     CDS             complement(17190..17417)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005151521.1"
                     /locus_tag="NQK81_RS06155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06155"
                     /product="hypothetical protein"
                     /protein_id="WP_257487433.1"
                     /transl_table=11
                     /translation="MASFKVKPSKPVAVFGAVGGMAVLVFVLVSGTGRGNGFVWLWAAL
                     CVGVVGFNLWAAFSERGATEVVERSATDRS"
     gene            complement(17601..18173)
                     /locus_tag="NQK81_RS06160"
                     /old_locus_tag="NQK81_06160"
     CDS             complement(17601..18173)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334986.1"
                     /locus_tag="NQK81_RS06160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06160"
                     /product="hypothetical protein"
                     /protein_id="WP_257487434.1"
                     /transl_table=11
                     /translation="MAEQLSLTGYQRGLRARILAAPTVAAPPPWRPADRHVAAVGGLLG
                     VGFAADPGTGRDLLLVESTNGLGLFDTVTGERLARDPDPDQPEGNDLTCQGIGPIAGHR
                     VPMAGLDGGGLHTGTTGWSVHVAGPDWPHERVLLSTGNPYTGGAHGETWWHIFHSRHSE
                     LRAAGFSPSGATLVVATSSDVTLWTRA"
     gene            complement(18225..19166)
                     /locus_tag="NQK81_RS06165"
                     /old_locus_tag="NQK81_06165"
     CDS             complement(18225..19166)
                     /EC_number="2.7.1.15"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335635.1"
                     /locus_tag="NQK81_RS06165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06165"
                     /product="ribokinase"
                     /protein_id="WP_257487435.1"
                     /transl_table=11
                     /translation="MADRMSRAIAVVASLNVDHIVQAPRIPEPGETLMGFSASRELGGK
                     GGNQAVAAARLGAEVAVIGCVGKDEDGDEYLAALRAEGADVTHVHRSALPTGRAAITVD
                     AEGVNSIVVVSGANGDIPAEAAEAAIFDLPGLRVVAGQLEAAPEATERAFAAARSRGVL
                     TVLNTAPADDVAGKLVPLSDVVVSNEIEFRQLTGQDPFDDDGLRRGGADLFAAGCRWVI
                     VTLGAEGCAVLDASSSTRVPAVPVRAVDTTAAGDSFVGALAARLAEVPGEPATADVVAA
                     CRFAARVAAVVVTRHGAHPSLPLLAEVPAFRR"
     gene            complement(19151..20185)
                     /locus_tag="NQK81_RS06170"
                     /old_locus_tag="NQK81_06170"
     CDS             complement(19151..20185)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335636.1"
                     /locus_tag="NQK81_RS06170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06170"
                     /product="phosphotriesterase"
                     /protein_id="WP_257487436.1"
                     /transl_table=11
                     /translation="MAEVRGVLGAVDAADLGLVLPHEHLFNDLSSAVAEPAYPSTRRLA
                     EAEVGPGWQFLLCQDPYCCADNVAPKDRASVVREVTAFAAAGGGTVVDATGSAAIGRDP
                     LALAAVAEATGVTIVMGTGAYLEKFEGERITAVAVDAQTERILAELDEGVGETGIRAGV
                     IGEVGVSPLFTDGERASLRAAALAQAARPTVGLNIHMPGWQRRGHEVLDLVLDECGALP
                     GKVALAHSDPSGEDPGYQRGLLERGVLLEFDMIGLDIAFPGEGVAPTVSQTARAVARWV
                     NEGFGDQIMLSHDLFLKQMWTRNGGNGLVFVPTIFADLLVAEGIAAEAVARLMRDVPAR
                     WLTA"
     gene            complement(20178..21173)
                     /locus_tag="NQK81_RS06175"
                     /old_locus_tag="NQK81_06175"
     CDS             complement(20178..21173)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335637.1"
                     /locus_tag="NQK81_RS06175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06175"
                     /product="DMT family transporter"
                     /protein_id="WP_257487437.1"
                     /transl_table=11
                     /translation="MSTSPTGRAASVVVLTIATVFAGMLGPLQSLVNGHLGTALADGHA
                     AALVSFGTGLVLMLIIVLARARTRDAFFRLPGQLVRGEIPRWNFFAGLCGAVIVLSEGV
                     TVGFLGVAIFQTSLISGMVISGVVCDRLGIGVPFKQAMSAPRVAGAILAICATVLVVSP
                     NWSAPHMIALAIMPFVGGLLAGWQPAGNSEVGLLSGSMFVSITWNFLIGFAALGLVYVV
                     RMVVSGAHFALPGTWWMYFGGPLGLLSIALMALLVRGLGLLLLGLASTAGQLIGSLLLE
                     VVAPAAGSSLHLVTVIGAVVALAAAAIAMIPSRHTAEPVVLAQPAEVRRG"
     gene            complement(21205..21957)
                     /locus_tag="NQK81_RS06180"
                     /old_locus_tag="NQK81_06180"
     CDS             complement(21205..21957)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335638.1"
                     /locus_tag="NQK81_RS06180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06180"
                     /product="glutamine amidotransferase"
                     /protein_id="WP_257487438.1"
                     /transl_table=11
                     /translation="MVKVLLAGESWVSATIDHKGYDPFAHTQVEIGCERLLAALAAEGV
                     EVTHLRSHDVAEKFPQTLEELGAYDVVLLSDVGSNTLLLHPDTFTRGRPTPNRLKLLRE
                     WVTNGGGLMMAGGYLSFQGFEGKANYHRTPIEEILPVDIDPYDDRVETPEGVRARVVRA
                     DHPVVAGLDQEWPILLGYQHTTLKPDAELLATVEGDVMLATRQVGSGRTLAFTSDISPH
                     WAPEEFMDWDGYRKLFAQAMTWLAGREL"
     gene            22067..23056
                     /locus_tag="NQK81_RS06185"
                     /old_locus_tag="NQK81_06185"
     CDS             22067..23056
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335639.1"
                     /locus_tag="NQK81_RS06185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06185"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_257487439.1"
                     /transl_table=11
                     /translation="MSLAKVAREAGVAVSTVSRYVKGELNVASETARRIDAALSAQGHP
                     PVQKQVTGLSLGLVVPSLDNPYFSTLADAVVDAAAADGIDVLTTLTGSSPLRERAAVER
                     LMRVPDVGGLVYLGMHNTNEAFASRLAGDFPVVFLDEYVEATGPRIAHVTANGFGGAYQ
                     ATTHLISLGHRRIAHVGGPAGLRTADQREAGYRAAMKTHGVEVDESMIVRGAFSSAFGM
                     NFFAHMARAGAEPTAVFTASDIAAVGLLEAARRAGVSVPGDLSVIGCDGITLGEWTSPR
                     LTTVAQPTEQMARKAVDEITRLAAGRVPADHVLSMQLVVRESTQEYPA"
     gene            23053..24111
                     /locus_tag="NQK81_RS06190"
                     /old_locus_tag="NQK81_06190"
     CDS             23053..24111
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335640.1"
                     /locus_tag="NQK81_RS06190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NQK81_06190"
                     /product="M20 family metallopeptidase"
                     /protein_id="WP_257487440.1"
                     /transl_table=11
                     /translation="MTDEALAFLRDLVRHDTTSGDSAAQAAAQELAVSYATATAGVRVL
                     RRSTTGRPWVLLGSHSGDGALFVCHIDTVPVGSPALWERAPFSADVDEEFLHGRGSVDM
                     KGGLVAALAALRNATEAGAGAQVLITSDEEIGCLGATEASASLDLTPRIVVVPEATRNR
                     VSLGHRGATWLRLTAEGKAAHGSTPQLGRNAIRLLADRALGALDSLPLAADDYLGGETV
                     NVGTFEGGTATNIVPASAVLTLDVRTVDGGAPAAAWASSLDPAITAEVDLDLPAVRTAR
                     LPELLAGRTTAPAATYFTDASALAGSVAGAPIVIWGPGDPRQMHAANEKLELESWRQAS
                     RDYLRLALSAAG"
ORIGIN
        1 catggccgtc aaggaggccg cccgcgcggc actgcggggt accgcggacg atcagtggcg
       61 cttcctgacc gtcgtgctct tcgccgagca caagaaggac gtcgaccggg tcatccagga
      121 cgacgccacc aaggacgaag cggccaaggc cgctgaacga gcgaaggccg ccaaggcgaa
      181 cgccgtgtcg cacacgctgg gatccgtgcc cccggcgcgg ctggagtacc tgatcaacct
      241 gaaggaccgg gatttcgtcg tcgaaatctg gaagtcggtc ccccgtgaca ccgaggtcca
      301 cggcgccgcc gaagacgccg tcggcagcct cgaccccgcc gactgggcct tcttcatcaa
      361 ccagggtgcc gaggaagcgc acctgcggga catcgtcaac gagctcgcca aacgcgacca
      421 ggagtacatc cggctgatca ccgaactgcg cacgcgcgcg gcgaaccagc tgatccggcc
      481 ggcgctggtc gccgccgcgg acgcggcact cgccgccaag cgcagcgatc gcgagaagtt
      541 ccttcgcacc ggccagtacg agaacctggt ccagaccttg cgggtcgacg cgtacagcgg
      601 tgtcgacgtc tacctcaccg accgcaacgg cgacgtcgtg ctcgagcagt ggcagccggg
      661 cgaccgtccg gaggcgcggt ggaggatcga gccggggctg agcaatcccg agtgcttctc
      721 gttccagtcg gtcagccgcc ccaaccacta ccttcgctgg cgttcgggag cgtcttccgc
      781 ggcgaacacg gcgatgatcc ccccgcagtc gcaacgtgtg cgggcctacg tcgacccgac
      841 cgacggctcc aacgccttca agggtgacgc gacctggtgc gtgcggggcg acgcctccag
      901 cgtctccatc cgcccctcgc gcagttccgc caagtacctg ttcgtcaccg gcgcgatcga
      961 tgacgacgcc tatgcgatcg cgacgaagtg gcacgccgag gctccgctgg ccccgcaccc
     1021 gatcgaccgg cgctacgccg cggagcagcc gctgcgcgac aagctcggca agcccgtcgg
     1081 cgacttcgtt cccgaaggga cttccaacgg ggtcggcctc ggccaccggt tgtacgaacg
     1141 gggcaggctc tacctcaccg ccgggaacga cgggaccact cagcgcttcg cggtgcaggc
     1201 ggtctacaac ggaccggtcc tcgacaagct actggcactc ggcgggcccg ccggcgtcgg
     1261 cggcgcgatg accgaccagg tgccgaccaa ggacggcaac ggccaggtcc tgcgggtcgt
     1321 caaacccacg atgggcgggc cgcacctcca catcgtgtgg agcgcgtcga cgggtgtcca
     1381 catcgtcttc ggcctgatcg gggagatctg ggcgaattcg ggcggggaaa cgggtcccta
     1441 cggctacccg ctcgccgacg agggcaccgt cagtggcacg aacgtccgct acagccggtt
     1501 cgccgcgggc accatctact acgtgcccgg tagcgcgatc cggcaggtca agggtgagct
     1561 ccaccggaag ttcgccgcca tgggcttcga ggcgggcatg ggttatcccc tggcggacgc
     1621 cggcacctac ggccccgacg ccagccccat gcagcgcttc acgtcgggct cggtgtacat
     1681 cacccgcaac ggaaccgtcg cgatcaacgg tgacatccac cggaagttcg ccgagcacgg
     1741 ttacgagacc ggtcctctcg ggaatccgac gggcgatatc cggtccactt cggacggtgt
     1801 gggcaaggtc gccgacttcg ccgtcggttc gggctcgatc tactggcatc ccagcaccgg
     1861 cgcacgcctg gtctacggga gcatcagcgc gaagtacaag tcgctggggg ccgagcgttc
     1921 gtacctcggc tacccgaagt ccgacgagac cgccctcccc atgggcaggc gcaacctgtt
     1981 ccagaacggc cggatcgact ggagcaatga gaccggctcg accgtcgcat accgggtcgc
     2041 ggcggtcccc cacaagacgg tcgatctcag gggagccaag tctggccgct gcatccagac
     2101 ggccggtctc atcggggaag gcgcgttgaa cgacctcgcc ggcatggaac tgtgggactg
     2161 cgtcggcggt gtcaagcagc tttgggacgt gacccatctc ggcaacaacg tctacgtcct
     2221 gaagaaccgc cactcgggga agtgcctcga cctgcggtac ggcgaactgc acaacggcaa
     2281 ctcgatcgtc cagtaccagt gccacaacgg gacgacgcag cagtgggagt tcaccaccac
     2341 cgcggacggc tcggtcgccc tgcgcagcgt gcattcggcg aagatcgtcg aagccgcggg
     2401 tggcgcggac cccaacgcca ccgccgtcgt ccagcaggtg gacagcggtc aggcgcacca
     2461 gcgatggacc gtccggccct actgatcgac gacaacgctt cgtgaggagc gagtgcgatg
     2521 acggccgcga cccggatcag ggtcgcggcc gttccgcacc tgaggccgtc acgaatcccg
     2581 gtgtcccgcc cagcctcctt ctttttcggc ggcgtccaca tcggcatcgg cggtcacggt
     2641 gtgcgccagc gcggcaacgg tctcctcgag cccgcgctgc acgtcctcgt catccgcgtc
     2701 ccggacgctg tgcagtgtca ccgtgaggcg ggacgccgcg ggaccggcgt cctcgatcga
     2761 cagttccccc tgatagtcgt gtggcccttg ggctccccag cgcagtgaac gattggcctc
     2821 gtcgaccttc agccacgcct cgccttccac atgttcaccg tggacgtcgg cttcgacgtg
     2881 caccgcctcg ccgccttcag gctcggcacg actcatccga gggaagtagc gaggcaggtt
     2941 ccgcggctct cgcaagtagg cgaacagatc cgcggcgggc atctcgatgg tcgcggtgtg
     3001 ccggtattcg gtcatgcggc cgggtacccc gcggcttgtg cgcgaaacgg caccgagccg
     3061 gactatcagc ggaaccgcga ggacgcccag cacgatcacg atcaggatcg tgatcccgag
     3121 tacgttcgcc gggatcagcg gcgcgatcac gaacagggcg accagcatcc agcccgccga
     3181 cgtgacgatc ccgacggcga acgatcgcca cttccggtcg ctcggccggc gcatcagcaa
     3241 gccgccgacg accatcaccg cgccgatcgc gccccaccac cactgctccc ccatgggctc
     3301 cccaccttcc tggcggcccc cggtcagtac cggagatcca ccaattcgaa cactcttatc
     3361 gtccgcacgg gctcggacgc gcacgtgagc cgcctgcccg ccgggattcg gccttcgcgc
     3421 aggtacacgg tgcagtcggg ttcggcgaag cccacctgcc aggtatcacc tgcacgcgtg
     3481 gtcttcgtca gccggagatc gtcgattcca gcggcgcccg tggcggcgcg ggcgtggtgg
     3541 tgagccgctt ggacgatcgg cggatacgag gaacggccac gcaggaacct gggatcgagg
     3601 atgccgtcca cgtactggtg atagagaccg atcgcgtcgt ccggacgcag gccgccgaag
     3661 gtgaaaccgt gtggcagcaa caccatcgag ggagcgaagc ggcagccgcc gaggtggctg
     3721 cattcccagg tggccccggg gaactccgcc gccagcgcgg tcgcgagcga acggccgcgc
     3781 accgcgcagc aggtgtcgtg tctgccgtgg acgcatacca gcgcgagggg ttccggccac
     3841 acgctccccg ccgcggaggt gacgcgggag agttccgcgg cgtcggtgaa ttccccggtc
     3901 cggatctgct cgtggccggg gcgagcgtcg acccggaacc agcggaaggg acggtcgcga
     3961 gtggacggac gccgggcgac ccggcggacc agagcgatcc ggccaccgac ccgcgccgcc
     4021 cacgaaccga ggtgggcgac cgccgccgga tcgatcccgg actccttgag cgcgaaccgg
     4081 ccccacgggc ccggatgctc gatcaggagc caatgctccg cgggcggggc cgttccttcc
     4141 ccgggatcgc ccgcggcttc ggccagttcc gcgcaccgtt gcgccgcggt catgcggtcg
     4201 aggccatcag cacgccttcc cggagcaggc ggcgcacgag tacgagctgg tcggcccggt
     4261 ccattcccgg gatctctccc agccgccacg tccttccgtc cagcagcgcc gccaaggcgg
     4321 tcgaggtgga ggcaggcaac gagaggcggc gatccgggag ttcgagaacg atccggccgt
     4381 ccgccggccc accgatacgg aagcgcaagc cgtcgcgacg ccgcaccgaa tccccgtcgc
     4441 cgaggcccag cacgaacctg gccgtcgcga tcggcgccag cggttccgga cgatttccgc
     4501 gccatgtcct gtcccggacg tgccgcgcga cggcgtcgcc gggcaccgcc cgcagggcgg
     4561 cgatcaggtc ttcccggacg gactcgacat gggcttccaa caggctcggg tccgcgacgt
     4621 cgatccccag cgggagcgat ttgcgcagcc gttcctcgga accggcgagc gcggtgagcg
     4681 cttccaccag ggcgaaggcg gtgatcacgt ggacgccgac ggtcagatgc gcggagacgt
     4741 cacccagcgc cgtcgccgaa tgcagccagc cgcgaggcag atacagcacg tccccgggcg
     4801 cgaggacttc gtcgatgacc ggagcatcgt cgcgggcccg tccggcgacg gcgtcggcgt
     4861 gctcgcccca cggctggtca cgcagaggcg acgggtggac gggcgcgtgc accttccacc
     4921 gcttgcggcc cgccgcctga agcacgaaga catcgtgcac gtcgtagtgc gccgagaagc
     4981 cctgcgacga cggcggggtg atgtaggcgt tgacctgcgc ggggtggccg agttcgccgg
     5041 tcaaccgcgt ggtgaagtcg atgatggcag gccagatgcg gtgcaatccc tggagcacga
     5101 tggtgctgcc ttcggcgaac agggcggcga cccggtcgtc acggacctgg tcgccgattt
     5161 ccgcgccgac accggctcca ccggtgaacg aacgggaatc gaccaccgcc ccgtcgcggg
     5221 ccagccgcag gaacggcgtc cgcaacccgc ggcgggacag catttcgtcg acgccgtcca
     5281 gatcgagcag atcaccgaag tcgccgccgg ttcgccgcag caacggttcc ctgccccagt
     5341 gccgggtggc gaactccgcg acgtcggaac cgaccagacg cgacaggaca cttgtcggca
     5401 cgtggccgtc caccggctcc gggacgcttt ccccggagcc ggtggacggc ccgctcagct
     5461 cagctcgcgc cactgtcggc gccgccgtcg gctccaccgt cgtgctggcc cgcggtgcct
     5521 tcgccggcgc cggaatcggc aggcccctcg gcgccaccgt cggccccgcc gtcgtgttcg
     5581 ccgggagtcc cctggccggc accggcgtcg gccggtcctt cccggtcctc gcccgaggtg
     5641 gtggagatgt cgtcgtcgtt caggctcatg tcgattccct ttcccatgat ccggatgaat
     5701 cagtggccgg ttaccccggt tcttcccgga gcacacgtgc gcggccatca cgatcggctt
     5761 acccgccacc acccgtcgca aaccgattcg agaccgattc accgcgtcgg atttccttgt
     5821 cccgcagact gcggaggcgg ctccggcgac gtacggtgag agcacgtgag gttcaactcg
     5881 cagcttcgcg tgttcggcga ccttgcccgg cctcgcaccg tccggccgaa gaccgggtgc
     5941 gtccggcgac gtgctgctgc gggcactcga agtgcgcgtc ataccgcttc ccgaggagac
     6001 ctccatgcca tcaccgcacc gaaaaacacc tgcccccgta ctggggcacg agcacgccac
     6061 cggtctgctg atcctcaccg tgaccggcga gctggacgcg agcacagccc cgctactgga
     6121 ccggcatctg gacgggaacc tccacgatcg gacggtgatc gatctgtccc gggtgacctt
     6181 tctcggcgtg gcggggcttc aggtgctgga ggccgccgtc acccgggccg gtcacgagcg
     6241 ccgtcggctg gccttggtca gttcgtcgcc gacggacctc aggatcttgc ggctcttcgg
     6301 cctcgacgtg cgggtgccgg tgtatccgcg gctgtcggac gcgatccggg aaatcgcctc
     6361 acaggtcccg tagcaccgcg cgagcggtcc gtcccccgga ggcgagcgcg ccctgcagcg
     6421 aactggtgtc gcggtgatcc ccgcagacgt aaagccgttc accgaaccgg atctcgccgc
     6481 ggacgtcgtg cggcggaggc atggccggga gcgcgcgggg gatctcgtag cgcgcgacca
     6541 acggccagcg cgaagcgtcc acacggtaca tccggctcag ttcccgccgc acttccgatt
     6601 ccccgagcgg catgagcgcc gaggcgctga cgagcgccga gccttccggg gcgtaagccg
     6661 ggcagacctc gctcagtaca gaggtgttga ggatcgggcc gccgcgggcg tcgaccacga
     6721 tgaccggctc tcgcaacggt gaccgtggtg gcgcgaaata ccaagtcgtg acgctgttcc
     6781 accgcggttc ggggacgccg tcgaccaggc ccgcggcggt ggtgccgtcc gtggcgacga
     6841 cgacggcgcg cgcggtccag acgtctccgc cggaggtgcg tacctcaccg tcgccgactc
     6901 gctcgacgcg cgttccggtc cgcaccgcgg aaacgggcag cagccgggcg agttgccggg
     6961 gcagctcgcc catgcccagc gacggcaacg acggcgcgga tcgcaggaaa ctgcgccaga
     7021 cgagccggaa gaaccgcgag gaggtactca acccggcctc caggaagacc ccggacagga
     7081 acgggcggag cacggtttcc accgcgcggt ccgacaatcc cgcaccgcgc agttcgtcgg
     7141 cggtcgtgcc gtcgcgtccc tggacgatcg accgcgccgg accgcccgcc gcccgcgcgg
     7201 tgaaggcacc gagcgcggct aggtccttcg ccgacagata gcgcctagcc gcgacgtccc
     7261 gcagcgcctt gggtgtgtcg agcgggtttc cgaggaggct gagccggtcg tcgtcggcca
     7321 cccggaccgc gcgccagaac ctgcccagcc gcagcgcgtc gacgtccacc aagcgctgga
     7381 tcgcggggta cgcgggattg aggatctgga agccgcggtc cagccggaag ccgtcgacga
     7441 cgtcggtccg cacgcggcca ccgacctcgt ccccggcctc caggacggtg cagacgacgc
     7501 ctgcgcggtg aaggtgcagc gcggccgaga gaccggcgag tccggcaccg atgaccacga
     7561 cttcggtttc gtgcacaggc atcggaaacg ctcctcggtg tcacggtgga cgcgaactca
     7621 gacgtgtcct gctcgcaagg cgtagcggcg ttccgcgtac gcgagatcgt cccgccacag
     7681 ccgcgcggac gcccggcgca tcaaaggccg cagtgccggg gcgatccggg cggccttcgc
     7741 gaacccagga cgttcggagg tcgcgatcgt cgcctcgatc acggcggtgc gcggacggcc
     7801 gtccgggccg gttccgagcg gggtggcatg cgtctccacc acgcttccgg tgccctcgcc
     7861 ttcgacgatg gtcatcagca cggtccgagg ctcggggcag gtgaattcgg cgatcaccgg
     7921 cacgcccagc ttcccggcga gccggaaggt cacttcgacc acgaacttgt cgtccgcgtc
     7981 ggcgacctcg tttccttgcg gcgccgaaac aacccgcagc cgcgtgaagg aatacgggtg
     8041 gaaccaggcg ccgtgccaag ggtcgagccg gttcgcgacg acgtccatcg gttcacagat
     8101 cccggtcagc gtcgcgaccg cgtcgaccgc gaggtctcct agcgggcggt ccggcacgac
     8161 cggccgttcc gtcggagcct caccgccgaa gcgatcgagg cggacccagg cgagcacacc
     8221 gtcgtcatag gacggcaacg acgtccagcc cggccgatcg gacccgaccc gaaggccgtg
     8281 ccatcggcag accaactctc cacaatggac acgcgcctcc gccagcggag cgcccagatg
     8341 aggacaggca ccgggaccga tggtcagggc accgtccgga ccgcgccagg cgaccagttc
     8401 ccggccgccc gcccgcaggc cgagtggctt gtccgcacgg atttcacggc tcgccgcgac
     8461 gacgaaccag ttgcccgcca cccgggcgtc ggcgcgtttg accgcggcgt cgatcagcgc
     8521 gggagcgcat tcccggtacg tcggttcctg ccgcgcccag gccggttccc ggaagggctg
     8581 gaccggccag ttcgacggcc accgctcgag cacctgccgc ctgagatcca ccacagactc
     8641 tcccgtcccg cgatatccga cggaaccatc ctctggcact tggagcgatc tcgcaacggt
     8701 tcaggacttc agccgctcgg cggcgacctc cagcgcgccg tcgagatcgt tgacccacgg
     8761 ggtgccgtgc acatcgagtc cttcccagcc gggccccgcg acgacgacct cgaaaccctg
     8821 ctgctggaga cgacggcgga gcaggtcgtc gaccgtggtg acggacatcg accagagcac
     8881 gatcagcacc ggatccagtt tcgaggccat gccggcgacg gtctccgcgg ggaccatctg
     8941 accgagatag accgcgggga taccgatctc gaccatcgac gcgcgaagga tctcgaccgg
     9001 caggctgtgc cgttcgtccg gacagcagga gaggagcgcg ccgcgttccg aaggtgccgt
     9061 ggcgaatcgg gcgacgtagc gctgcaacgc cagggagacc tcggtggtga gcgcccattc
     9121 cgattcgaag cagacgtcgc cccgctgcca gcggccgccg aggttccgca ggatgggcag
     9181 gagcacgtcg gtccacgtcg ccgccgcgcc gagcgagtcc agcgtttcgt cgagcaacgc
     9241 ggcgatggag gcgaactcca gatcttccgc ggcccgttcc agttcgtcga cccgccggtc
     9301 ggccgggact tcggggagcg cggctgcggc gccggagaac gcggccgcgg cggcctcacg
     9361 ggcacggata ccgcggtcga tcagccgctg catgtgctgg agcctgcgga cgtccgcgtc
     9421 cgagtaccgg cgatgacgcc cgtcggccct cagtgaaggt cccacgccgt accgcgtcgc
     9481 ccacgtccgg agcgtgaccg gcgagatgcc cagcacttcg gcgaccttgc cgggcgtcca
     9541 cgaacccgtg ggccgaaggc cgttctcctc gtcgacttcc attcagtacc acgtttcgca
     9601 cgaagacatc cgatgcccga gcttacgttg ctcaccgtcg gtcgaatctc gaacacggta
     9661 cgtatggcgt ccactgagga acgaacgccc ggcggtgccg agggcgatcg ggaggggacc
     9721 gatccgccag gcaccgccgg gcgtccggaa cccggctcag gggaggggcg ccggattccc
     9781 ggagggtggc gaggtcccgg ccacctccgt cgctgggcgg tcatcttcga ttcgtgagcg
     9841 atccggggtt tgagcccgga actcgaggga accccggctt ctggcgtcta ccggaggatc
     9901 ccgctcgagt tgcgaggctg tcacccgatc cagtagacaa ggtacaccgg caatgaaacg
     9961 gttgcgaatc gaatcaccgg atggcggaag ggacggtcgg atggcgtcga tcatggcgga
    10021 agaggcgccg gccgcctggc tggacaccct gggccgacgt tgcctcgccg aggcgtacgg
    10081 tttcgtcgag gcacgggccg ccgaacattt cgccggccac ggcgagggtg aactcgccga
    10141 gaccgtcatc ccggagttcg tcgcgggcgg gaaattcctt cgcccgatgt tcgcctacgt
    10201 gggctggcga tgcggcggac cggaatcgga cgcggccttg cgggccgcgg cgagtttgga
    10261 actgctccac tgtttcgcgc tggcgcagga cgacgtcatg gacggctcac cgctgcgccg
    10321 cggccgcccg gcgctgcacg tccggttcgc gcgctggcac accgaacagg gctggagcgg
    10381 atccgccgac cgcttcgggg aatccgcggc gaccctgtcc ggcgatctct tcctggtctg
    10441 gtcggagcgg atgctccggg aatccggcct cgacgcggcg gcgctggccc gcggctggcc
    10501 gcgatacgac ctcatgcgcg cggaactggc ggtcgggcag ctcgccgatc tcgtgaacga
    10561 cgccaggacg ctcccggact gggagacact gctcgacgtc ctgcgccgga agtccggcaa
    10621 ctacaccgtc cgcaggccgc tcgaattcgg cgccgcgctg gcggggtgcg ggccggacgt
    10681 cctggccgcc ctcgccgaat acggcggcct ggtcggtgag gcgttccagt tccgggacga
    10741 tctgctcggc gtcttcggcg atccggcggt caccggcaag cccgcgggcc aagacctccg
    10801 tgatcgcaag gcgtccagtg tcgtggtgct cgccgccgag atggccgacc ggcggcagcg
    10861 cgcggaactc ggcgaactgc tcgcgccgtc gacggtggac gacgaagccg tggcccgctg
    10921 gcgcgccctg atcacggcga ccggggcgcg ggaacgcctc ggcgagctca tccgggaacg
    10981 ggccgagaag gcccaggccg tgatcgaccc ggccgtgttc cctcggcacg ccgcggattc
    11041 gctggccgtc ctggccacca aatgcacgga gcgcgaccag tgaaaacggt gccggggccc
    11101 acggaccggg tcgtcgtggt gggagcgggg ctgtcgggac tcgcggccgc cctgcacttg
    11161 gcgggccgtg gacgctcggt caccgttctc gaacgcgacc ccggtccggg tggccgcgcg
    11221 ggacgcgtcg agcgtaaggg ctatctgctc gacaccgggc ccacggtgct caccatgcct
    11281 tcgatcctgc gggacacctt cggcgccgtc ggcgccgagc tgagcgagga attgccgctg
    11341 atccgtctcg acccggcgta cgtggcgcag ttcgccgacg gcagcacgct gcccgtgcac
    11401 acggacgccg cggcgatgac ggacgcggtc cgcgagttcg cgggcccggc ggaggccgcg
    11461 ggttacgtcc ggctccgcga atggctgact cgcctgtatc gcaccgagtt ctcccggttc
    11521 atcgactcga acatcgactc gccgccgggc atgctccggc cggaactggc gcggctggtg
    11581 gcgctcggcg gcttccggcg gctggatccc aagatcggct cgttcctgtc ggacgagcgg
    11641 ctgaagcggg tgttcacctt ccaggccctc tacgcgggcg agtcgccgat gcgggcactg
    11701 gcgctctacg cggtcatctc ctatatggac accgtcggtg gcgtgtattt cccgcccgga
    11761 ggtgtcgcgg cgctccccca ggccctcgcc cgcgtcgccg cggcgaacgg ggtcgtcttc
    11821 cactacggcg accccgtgaa cgcgctcgaa cgggacggcg gccggatccg cgcggtccgc
    11881 accgcgggcg gcgaacgcca cccgtgtgac gccgtcgtgc tgacgaccga gccacccgag
    11941 agctaccggc tcctcggccg gcacccgaag cggcccgtcc cgctgcggcc agcgccgtcc
    12001 gcgctgatcc tgcacaccgg aggcccaggt gagcactccg ccatcggcca ccacacgatt
    12061 tccttcgggc agggctgggc ttcgaccttc gacgagctca tctccaccgg gcgccgcatg
    12121 accgatccgt ccctgctgat cacccggccc accgcgaccg atccgggact cgccccgccg
    12181 gggcggcagc tcttctcgat cctcgcgccg gtacccaatc tcgaccgtgg cccggcggac
    12241 tggaccgccg atgcgggccc gtacgccgag gagatccttt ccgtggcccg ggaacgcctg
    12301 ctgccggatt tcgaacccga gttcaccgag gtgatcagcc cagccgattg ggcggaccgc
    12361 ggcctggtcg ccgggacccc cttcggctac gcgcactcgt tcggtcaaac cggaccgttc
    12421 cgtcctagga acttcccgcg cggtaccgaa aacgtcgtcc tcgccggcgg cgggacggtg
    12481 cccggcgtcg gagtcccgac cgtgctgatc tccggcaggc tggccgccga ccggatcacc
    12541 gggacaccga tgcgcggcgc ggaggcgaac cgatgaccaa gcacgaactc gacgccgccg
    12601 gcatccgcga tccacacctt cgtgccgcct atacgtggtg ccgcggcctc aatgcccgcc
    12661 acgggcgcac gtacttcctg gcgacccgca tgctgaccgc gccgcagcgg cccgcggtcc
    12721 acgcgctcta cggtttcgcc cgatggctgg acgacatcgt cgacgaaccg gatcccgccg
    12781 ccacgccgcg gtcactggcc gcgcgactgt ccgaagtgga gggtcgcttc cgcgccgatc
    12841 tggcctcggg cacgagtacg gatcccttgc tcagagcggt gatcgacacg gcggccaggt
    12901 acgagctcga agaacacctc ttccgcgcct tcctcacgtc gatgcggatg gatctgagcg
    12961 tcaccggcta cgccacgcga gacgacctcg acgtctacgt gcacggctcg gccgaggtga
    13021 tcggcctgca ggtgctgccg atcctcggcg cggtgaccca ccgcgaggag gccgccccgc
    13081 gagcggccgc gctgggcaag gcgttccagc tgaccaactt cctccgcgac gtcgccgagg
    13141 atttcgcgcg aggacgggtc tacctgcccg cggacgagct caaggtgcac gacgtcgacc
    13201 gggaccggct ggcctggtgc gccgagcacg gccgggccga cgcaccggta cgggcggcga
    13261 tcagggacca gatcgcggtc acccggcgga tctacgccga ggcacggccc ggaatcgcga
    13321 tgctgcaccc ggtctcgcgc ccttgtgtcg ccaccgccgc gaccctctac ggggagatcc
    13381 tcgaccggat cgaggacgca ggccacgacg tgttcgcccg ccgggtgagg gtgacacgcc
    13441 gccgacggct cggggtcgcc tgcggcgcat tcgctcgttc ccagtgggcc cgcaggcggc
    13501 atccggcgcc cgctcccccc gcggcggtga gctgagtggg caaattcgag tacctgatcg
    13561 tcctcgcggc ctgtgtcctg gtgaccctgc cgctggaaat ggcgggcgcc cgcgtctacc
    13621 ggcaaccgaa acggctcgcc cgcgccctgc tcccggtggc gctggtcttc ctggtctggg
    13681 acgcgctggc gatcgccgcc ggggtctggg gctacgcacc ggaattcatg accggcgtcc
    13741 acgccccgtt cgccatcccg ctggaggaga tcctgttctt cgtcgtcatc ccgatctgtg
    13801 gcttgctcac ctacgaaatg gtccagcttt cgctcaccgt ggcccggcgc cgcggcgaac
    13861 gggcggtccg ccggtgattc cctggggtta caccgttccg gccgtcgtcg cggtggtcgt
    13921 ggtcgtgctc gccgaggtcg tcgtgctgaa gaccggtctg ttccggaaac ccgcctactg
    13981 gatcacgatg gccatcgtcc tcggcttcca gatccccgtc gacggctggc tgacgaagtt
    14041 gtccgcgccg atcgtcctct acgcgcccga gcacgtcacc ggctggcgct tcccgtggga
    14101 catcccggtc gaggacttcc tcttcggcta tgcgctggtg accgccgttt tgctgctgtg
    14161 ggaacggtcc cggccacgcg aggaggcgcg gtgaacgccc tggcgcgtga cggcctgccg
    14221 cgggacaccg tgccgtcggc cttcgacacc gaagcccgct tctacgaccg tctggtgcgg
    14281 gcgaatcccg gctatcaccg gcatctgctg ctgtccgccc agcggctcga tctgccgtac
    14341 gacggccagc accttcgatt gctcgacgcg ggctgcggca ccggcgcgtc caccgccgcg
    14401 ctcgtcgcgg cggcacccgg agcgaagatc acggcgttcg acgcctcccg cgaaatgctg
    14461 gcgcgagccc gggacaagac ctggcccgaa ggggtcgagt tcgtccacac ctcagcggaa
    14521 gagctggcgg gggtggaggg gccgttcgac gcgatactgg cggcctatct cctgcgcaac
    14581 ctcgccgacc ccacgagcca gttgcgccgc ctgcgtggcc tgctgcgccc gggcggccgg
    14641 atcgccgtgc acgaatactc ggtccgggac tcccggcgag cccgctgggt ctggaacgcg
    14701 gtctgcgcgg ctgtgatcat ccctctcggg aaggtcgtca ccggcgacgc cacgctctac
    14761 cgccatcttc gccgcagcgt cgccgagttc gacggaatcg gctctctcgc ccaccgtctc
    14821 accgacgccg gcttcaccga cgtccacacc gccaccgtcc ccggctggca acgcgacatc
    14881 gtgcacaccg tcgtcggcac agctcccgag gagactccgt gacctctccc ctggaccgcc
    14941 gcctggtcac ctatccggcg tcgcgcggcc tcgcggacgc cgggcaactc ggcgcgcgcc
    15001 ccacggtggc cgtcgtgggc ggcggcatcg ccggtctcac cgcggcgacc ggactggccg
    15061 aacgcggcgt caccgtcacc gtcttcgaac gagaagacca tctcgggggc cgggtcggcg
    15121 gctggcggga gcggctgccg gacggcactc cggtgacgat gagccggggc ttccacgcct
    15181 tcttccgcca gtactacaac ctgcgtacct tgctgacccg cacggatccg cattcggagc
    15241 ggctcactcc gctctccgac tacccgctgt tggacgcgca cggccgcatc gacaccttcg
    15301 ccgggctccc tcgcacaccg atctggaacg cggcggtttt cgccttgcgg agcccgactt
    15361 tcacccccag ggacctcctg cggctcagtg gacgcgaggc gttgccactc gccacggtca
    15421 gcgtgcccga gacctatcac cggctcgatc acatcgacgc gtcgaccttc ctcgaagcga
    15481 tcaacttccc agcggccgca cggcatctcg cgttcgaggt gttctcgcgc agcttcttcg
    15541 ccgacccgcg ggacctgtcc gccgcggaac tggcggccat gttccacctc tatttcctcg
    15601 gctccagcga aggactcgtc ttcgacgtgc cgaccgagcc gttcccgcag gcactgtggg
    15661 atccgctcgc gagctacctc gccgggcgcc gcgtcgaaat ccgcaccggc gcggcggtca
    15721 ccgccctcgg ccggacgccg gacggtttcg aagtcgagac cggtggccgc acggagggct
    15781 tcgacggggt ggtgctcgcc tgcgacatcg ccgggctgcg cgacctcgtc accgcatccc
    15841 cggacctcgc gaccgagtcc tggcggcgcg cgatcgggga actgcgcacc gcgccgccct
    15901 tcctcgtccg gcggctctgg ctcgaccggc cggtcgagcg acgacgtccg cctttcctcg
    15961 gcaccggcag cgtcccgccg ctggacaaca tcagcctgct cgaccggtac gaaggcgaag
    16021 cacggcgctg ggcggcgcgc accggcggct ccgtcgtcga actgcacgcc tacgcggccg
    16081 ccaccgcgga tcaaagcggc ttggagaaag ccctcgaaca acggcttcac gagatctacc
    16141 cggagacccg ggacgcgcga gtggccgggg aaagcacgtt gtggcgcgag gattgcccac
    16201 tgttcggagt cggcgacttc gcccggcggc cggccgtgcg gactcccgac ccgctcctcg
    16261 cgctcgcggg cgacggcatc cggatcgacc tgccggtcgc cctcatggag cgcgcggccg
    16321 ccaccggctg ggccgcggcc aacacccttc tcgggcattg gggcctcgcc ggtcacccgc
    16381 ttcgttcggt ccccaaccga ggacggatcg gcctgttgaa ccggctggcc gcttcgaagt
    16441 acgtcggcgg gggccggaga cggcgaaccg ggctcgccgc gggctgaacg gccgccgtcc
    16501 tggtcttcag ctcaagaggt cgaggccgcg ctgccaccgc tgccgacgct ccgcctggtc
    16561 ctgctcccac cacggagttc cacgctcccc caaggcgacc ttggcgatgt gcacccgcgc
    16621 ccgggcctcc cgctcggctt cgggatcctg agctcgccgg gccgcgccga cgtcccggcg
    16681 ggcccgcatc agcaggccgc gcaaccgggc cgccgtctcc tccggtatct ccggatcggt
    16741 cgcgcgccag cgccggccgc cgatcacgac gaaacgcccg tcgggggtgc ggtccggctc
    16801 agtcatccgc gtccccggcc agccggatcc tgatgggccc ctcccattcc gcgtccgggt
    16861 cgagcgaccg ggcgccctgg gtcaaccgca cctcccccgc ccgcgcgagt tcgcgcgcca
    16921 gttcccgagc ccgcggcagc aacggacgcc actcgtccgc gagcgcccgg gccgcgtcgg
    16981 aagggcagca gctgccgcat tcgcctcgcg cgaaggccaa ggcgaggatc gccgcccgca
    17041 accgatcggg caccggcccg gtacccagcg ccgtccgggc atgaaccgcg cccggcccgg
    17101 cgttctccag gatccgctcc agttctcgtc gaggccctga cctgctcgtc ataccgccag
    17161 gatcgcaccg ccccgccgag tcagcccggt caagaccggt ccgtggcgct gcgttcgacg
    17221 acttcggtgg cgcctcgttc gctgaacgcc gcccacaggt tgaaccccac caccccgacg
    17281 cagagggccg cccacaacca gacgaagccg tttccgcggc cggttccgct gaccagaacg
    17341 aacaccagca ccgccatccc accgaccgct ccgaacacgg cgaccggttt ggagggtttc
    17401 accttgaacg acgccacccg gagactcctc gcgtagaacg aattacggcg agaccgtgat
    17461 gcccctgccc ggtaccgcct aaacaccttt cgtccggcag ctcggacgcg agggacatcc
    17521 agcgctgacg tgagccgaag ggcgccttca ccgcacgaca tggggcgaag aacgctttca
    17581 gcccacctcg ggggcctggg tcaggccctg gtccagaggg tgacgtcgct gctggtcgcc
    17641 acgaccagcg tcgccccgga cggcgagaac ccggccgccc gcagttcgga gtggcgcgaa
    17701 tggaagatat gccaccaggt ctcgccgtgc gccccaccgg tgtacggatt cccggtggac
    17761 agcagcaccc gctcgtgcgg ccagtccggg cctgcgacat gcaccgacca ccccgtggtg
    17821 ccggtgtgca ggccgccgcc gtccagcccg gccatcggca cgcgatgccc cgcgatcggc
    17881 ccgatccctt ggcacgtcaa gtcgttgccc tccggctgat ccggatcggg gtcgcgggcc
    17941 agccgttcac cggtgacggt gtcgaacagc ccgagcccgt tcgtcgactc caccaacagc
    18001 aagtcgcggc cagtgccggg gtcagcggcg aaaccgacac cgagcaaccc gccgacagcg
    18061 gccacgtggc ggtcggctgg acgccacggc gggggcgccg ccaccgtcgg cgcggccagg
    18121 atccttgccc gcaggccccg ttgatagccg gtgagcgaaa gttgttccgc catcccgcga
    18181 gtatgccgga ggccggacgc tggatcagcg catattcacc cggctcaccg ccggaatgcc
    18241 ggcacctcgg ccaagagcgg caaagaaggg tgcgctccgt gccgcgtcac gacgacagcg
    18301 gccaccctcg ccgcgaaacg gcaagccgcc accacgtccg cggtcgccgg ctcaccggga
    18361 acttccgcga gccgggcggc gagcgctccg acgaacgaat cgcccgcggc ggtggtgtcc
    18421 acggcccgta ccgggacggc cgggacgcgc gtggacgacg acgcgtcgag gacggcacat
    18481 ccttcggcgc ccagcgtcac gatcacccac cggcatcccg cggcgaacag atcggcaccg
    18541 ccgcgccgca aaccgtcgtc gtcgaacgga tcctggccgg tgagctgacg gaactcgatt
    18601 tcgttcgaca ccacgacatc gctcagtggc accagtttcc cggcgacgtc gtcggcgggc
    18661 gcggtgttga gcacggtcag cacgccccgc gagcgagcgg ccgcgaaagc gcgttccgtc
    18721 gcttcgggtg ccgcctccaa ctggcccgcg acgacccgaa gccccggcag gtcgaagatc
    18781 gccgcttcgg ccgcctccgc tgggatgtcg ccattcgccc cggacacgac gacgatcgag
    18841 ttgacgcctt ccgcgtcgac ggtgatcgcc gcccggccgg tgggcaaagc ggaccggtgc
    18901 acgtgggtca cgtcggcacc ttcggcgcgc agggctgcca ggtactcgtc gccgtcctcg
    18961 tccttgccga cgcacccgat cacggccact tccgcgccga gccgggcggc ggcgaccgct
    19021 tggttgccgc ctttaccgcc cagctcccgg ctcgccgaaa atcccatcag ggtctccccc
    19081 ggctccggga tgcgcggcgc ctggacgatg tgatcgacgt tgagcgacgc gaccaccgcg
    19141 atcgcgcggc tcatgcggtc agccatcggg cggggacgtc ccgcatcagc cgggcgacgg
    19201 cttcggccgc gattccttct gctacgagca gatcggcgaa gatcgtcggc acgaacacga
    19261 gcccgttccc gccgttgcgc gtccacatct gcttcaggaa caggtcgtgc gacagcatga
    19321 tctggtcacc gaagccctcg ttcacccacc gggccacggc gcgagcggtc tgggaaaccg
    19381 tcggggcgac gccttcgccc gggaacgcga tgtcgaggcc gatcatgtcg aactccagca
    19441 gcacaccgcg ttcgagaaga ccccgctgat atcccgggtc ttcgccggac ggatcgctgt
    19501 gcgccagcgc cacttttccc ggaagcgcac cgcattcgtc cagcacgagg tcgagcactt
    19561 cgtgcccgcg acgctgccag cccggcatgt ggatgttcag ccccacggtc ggccgcgccg
    19621 cctgcgcgag cgcggcggcc cgcaaggagg cccgctcccc gtcggtgaaa agcggcgaaa
    19681 caccgacctc gccgatgacc ccggcccgga tccccgtctc gccgacaccc tcgtccagtt
    19741 cggcgaggat gcgctcggtc tgcgcgtcga cggcgaccgc ggtgatgcgc tccccctcga
    19801 acttctccag atacgcaccg gtgcccatga cgatggtgac cccggtggcc tcggcgaccg
    19861 ccgccagggc gagcggatcc cggccgatcg ccgcgcttcc ggtcgcgtcg accaccgtgc
    19921 cgccgcccgc cgcggcgaac gcggtcacct cgcgcacgac gctcgcccgg tccttcggcg
    19981 ccacgttgtc ggcgcagcag tagggatcct gacagaggag gaactgccag cccggcccca
    20041 cttccgcctc ggcgagccgc cgcgtggagg gataggcggg ctcggcgacc gcggaggaca
    20101 gatcgttgaa gaggtgctcg tgcggcagca ccagcccgag atccgccgcg tcgaccgcgc
    20161 cgaggacacc gcgcacctca gccacggcgc acctcggcgg gctgggcgag gaccaccggt
    20221 tcggccgtgt gccgggacgg gatcatcgcg atcgccgcgg ccgccagcgc cacgaccgca
    20281 ccgatgacgg tgaccaggtg caggctggaa cccgccgcgg gagcgacgac ttcgagcagc
    20341 agcgacccga tgagctgacc ggccgtggag gccagcccca gcaacaggag cccgagacca
    20401 cgcaccagca aggccatcaa cgcgatcgac aggaggccga gcggtccgcc gaagtacatc
    20461 caccaggtgc ccggcaacgc gaaatgcgcg cccgagacga ccatgcgcac cacgtacacg
    20521 agaccgagcg ccgcgaagcc gatgaggaag ttccaggtga tggaaacgaa catcgagccg
    20581 gacagcaggc cgacctcgga gttgcccgcg ggctgccagc cggcgagcag gccgccgacg
    20641 aacggcatga tcgccagcgc gatcatgtgc ggggccgacc agttcgggga caccaccagc
    20701 accgtggcgc agatggcgag gatcgccccg gccacgcgcg gcgcgctcat cgcctgcttg
    20761 aacgggacgc cgatgcccag gcggtcgcac accacgccgg agatgaccat gccggagatc
    20821 agcgaagtct ggaagatcgc gactccgagg aaacccaccg tgacaccttc ggaaagcacg
    20881 atcaccgcac cgcacaggcc ggcgaagaag ttccaccgcg ggatctcgcc gcgcaccagc
    20941 tgaccgggca gccggaagaa cgcgtcgcgt gtccgggcgc gcgccagcac gatgatcagc
    21001 atcagcacca ggccggtgcc gaaggacacc agcgcggcgg cgtgcccgtc ggcgagcgcg
    21061 gtgccgagat gcccgttgac gagtgattgc aacgggccga gcattccggc gaagacggtc
    21121 gcgatcgtca ggacgacgac cgaggccgcg cggccggtgg gtgacgtact catcgaatcc
    21181 tccttgatcc cgagtgcgcg cggctcagag ttcgcggccg gcgagccagg tcatcgcctg
    21241 cgcgaagagt ttgcggtaac cgtcccagtc catgaactcc tccggagccc agtgcgggga
    21301 gatgtccgag gtgaacgcga gcgtgcggcc gctgccgacc tgacgcgtgg ccagcatgac
    21361 gtcgccttcg acggtggcga gcagctccgc gtccggtttc agcgtggtgt gctggtagcc
    21421 caggaggatc ggccactcct ggtcgagacc ggcgaccacg gggtggtcgg cccgcacgac
    21481 gcgggcacgg acgccctccg gcgtctcgac gcggtcgtcg taagggtcga tgtcgaccgg
    21541 caggatctcc tcgatcgggg tccggtggta gttggccttg ccctcgaagc cctggaagct
    21601 caggtagccg ccggccatca tcaggccgcc gccgttcgtg acccactcgc gcagcagctt
    21661 gagccggttg ggggtcggac ggccgcgggt gaaggtgtcc ggatgcagca gcagcgtgtt
    21721 ggagccgacg tcggagagca ggacgacgtc gtaggcgccg agttcctcca gcgtctgcgg
    21781 gaacttctcg gccacgtcgt gcgaacgcag gtgagtcacc tcgacccctt ccgccgccag
    21841 cgccgccagc agccgctcgc acccgatctc cacctgcgtg tgcgcgaacg ggtcgtatcc
    21901 cttgtggtcg atcgtcgcac tgacccacga ctccccggct agcaggacct tgaccatcga
    21961 cgactccttc gggcgaaagc ggtagcgttt gttgcgcaac atagcgcaac gccgccaata
    22021 taagatgcgc tgcagtcgcc gtcaacgctc aacggggagg agccggatgt cgctggcgaa
    22081 ggtggcccga gaggccggag tggccgtgtc gaccgtgtcg aggtacgtca agggagagct
    22141 caacgtcgcc tccgagacgg cccggcgcat cgacgccgca ctgtcggccc aagggcatcc
    22201 gcccgtgcag aaacaggtga ccggcctcag cctcggcctg gtggtccctt cgctggacaa
    22261 tccgtacttc tccacgctgg cggacgcggt ggtcgacgcc gccgcggccg acggcatcga
    22321 cgtgctcacc acgctcaccg gctcgtcgcc gttgcgggag cgcgccgccg tcgagcgcct
    22381 gatgcgggtg ccggacgtgg gcgggctggt ctacctgggg atgcacaaca ccaacgaagc
    22441 cttcgcgagc cggctggcag gggacttccc ggtcgtcttc ctcgacgagt acgtcgaagc
    22501 caccggtccg cggatcgcgc acgtcacggc gaacggtttc ggcggcgcct accaggcgac
    22561 cacccacctg atctccctgg gccaccggcg gatcgcccat gtcggcgggc cggccgggct
    22621 gcgcacggcc gaccagcgcg aggccggcta ccgggcggcc atgaagaccc acggggtcga
    22681 ggtggacgag tcgatgatcg tgcgcggcgc cttcagctcg gcgttcggca tgaacttctt
    22741 cgcgcatatg gcacgggccg gcgcggagcc gacggccgtg ttcaccgcca gcgacatcgc
    22801 cgcggtcggc ctgctcgaag cggcccgccg cgccggggtg tcggtgcccg gagacctttc
    22861 ggtgatcggc tgcgacggga tcaccctcgg cgaatggacg tcgccgcggc tgaccaccgt
    22921 cgcgcagccg accgagcaga tggcccgcaa ggcggtcgac gagatcaccc gcctcgcggc
    22981 cggccgcgtc cccgccgacc acgtgctctc catgcagctc gtcgtccgcg aatcgaccca
    23041 ggagtacccc gcatgaccga cgaagccctc gcgttcctgc gcgacctggt gcgccacgac
    23101 accacctccg gcgacagcgc cgcgcaggcc gccgcgcagg agctggccgt ctcctacgcc
    23161 accgccaccg cgggcgtccg cgtgctgcga cgctccacca ccgggcgacc gtgggtgctg
    23221 ctcggcagcc attccggcga cggagcgctg ttcgtgtgcc atatcgacac cgtccccgtc
    23281 ggctcccccg cgctgtggga acgcgcgcct ttctccgcgg acgtcgacga ggagttcctg
    23341 cacggccgcg gcagcgtcga catgaagggc gggctggtcg ccgcactggc cgcgttgcgc
    23401 aacgccacgg aagccggtgc cggcgcgcag gtcctcatca ccagtgacga agagatcggg
    23461 tgcctcggcg cgaccgaggc ttcggcctcg ctggacttga cgccgcggat cgtggtggtt
    23521 ccggaagcga cccggaaccg cgtctcactc ggacaccgcg gcgccacctg gctgcggctc
    23581 accgcggaag ggaaagcggc ccacggctcc acaccccagc tcggccgcaa cgcgatccgg
    23641 ttgctcgccg accgcgctct cggcgcgctc gattccctcc cgctggccgc cgacgactat
    23701 ctgggcgggg aaaccgtcaa cgtcggcacc ttcgagggcg ggaccgcgac gaacatcgtg
    23761 cccgcgtcgg ccgttctgac gctcgatgtg cgcactgtgg acggtggggc accggcggcc
    23821 gcctgggctt cgtcgctcga tccggccatc accgcggagg tggatctcga tctgcccgcc
    23881 gtccggaccg cgcgcctgcc cgagctgctc gccggccgga ccaccgcacc cgccgccacc
    23941 tatttcaccg atgcgtcggc cttggccgga tcggtggccg gagccccgat cgtgatctgg
    24001 gggccgggag atccccggca gatgcacgcg gccaacgaaa agctggaact ggaatcctgg
    24061 cggcaggctt cgcgcgacta tctgcggctg gcgttgtccg ccgcgggctg accggttcgg
    24121 tcacccgtgc cggatcccgt cgatcagcat gcgcacgagt tgctccacgc tgacctgcca
    24181 cgtgtccttc gcca
//
