MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
AAD21216.2 BacR BGC0000310.5 NRPS:Type I 43.0 98.7 194.0 8.2e-62
AEE65494.1 response_regulator BGC0000223.5 PKS:Type II 40.0 97.8 181.0 8.46e-57
ABI75119.1 transcriptional_regulator_OmpR_family BGC0000188.5 other:other 42.0 100.0 169.0 1.37e-51
ALJ99879.1 FlsR3 BGC0001904.2 PKS:Type II aromatic 38.0 97.4 167.0 2.25e-51
AAS79471.1 putative_two-component_system_response_regulator BGC0000035.5 PKS 44.0 99.1 164.0 3.5e-50
CAH60130.1 putative_two-component_response_regulator BGC0000700.5 saccharide 41.0 102.6 163.0 8.33e-50
AAX57187.2 atypical_response_regulator BGC0000201.5 PKS+saccharide:hybrid/tailoring 41.0 95.7 161.0 6.21e-49
MUL41494.1 response_regulator_transcription_factor BGC0002045.3 PKS:Type II 43.0 97.0 159.0 1.63e-48
CAJ34389.1 putative_response_regulator BGC0000445.5 NRPS:Type I 40.0 97.4 159.0 3.25e-48
AEG64695.1 response_regulator BGC0000379.5 NRPS:Type I 44.0 97.4 157.0 1.16e-47
QCT05734.1 Tri1 BGC0001983.3 other:other 41.0 97.4 154.0 1.84e-46
KON97034.1 DNA-binding_protein BGC0002122.2 NRPS:Type I 36.0 96.1 152.0 9.73e-46
BAQ25486.1 two-component_system_response_regulator BGC0001288.5 PKS 42.0 97.4 152.0 1.67e-45
EDY47143.1 two-component_system_response_regulator BGC0000845.5 other:non-nrp beta-lactam 41.0 97.4 152.0 3.57e-45
ABO65653.1 Subtilin_biosynthesis_regulatory_protein_SpaR BGC0000515.4 ribosomal:RiPP:Lanthipeptide 34.0 96.6 149.0 2e-44
AEE65471.1 two_component_regulater BGC0000223.5 PKS:Type II 40.0 98.3 149.0 2.53e-44
ADM69285.1 transcriptional_response_regulator BGC0001727.3 ribosomal:RiPP 35.0 100.4 149.0 3.43e-44
CAB60254.1 MrsR2_protein BGC0000527.5 ribosomal:RiPP:Lanthipeptide 34.0 98.3 148.0 7.03e-44
AGU42430.1 Cmm22 BGC0000842.5 other:non-nrp beta-lactam 39.0 97.4 145.0 5.49e-43
CAK15802.1 putative_DNA-binding_response_regulator,_OmpR_family BGC0000344.5 NRPS:Type I 41.0 91.8 145.0 6.2e-43
ACN38369.1 putative_two-component_system_response_regulator BGC0000714.5 saccharide 41.0 97.8 144.0 2.44e-42
BBA97247.1 putative_two-component_system_response_regulator BGC0002383.3 PKS 38.0 96.1 142.0 4.78e-42
CAF31457.2 putative_two-component_system_response_regulator BGC0000696.5 saccharide 41.0 96.1 143.0 4.85e-42
ARV75734.1 putative_two-component_system_response_regulator BGC0001603.3 saccharide 41.0 96.1 143.0 4.85e-42
KON97026.1 PhoP_family_transcriptional_regulator BGC0002122.2 NRPS:Type I 35.0 98.3 143.0 6.37e-42
OKI59850.1 transcriptional_regulator BGC0002477.3 PKS 39.0 95.7 139.0 8.9e-41
ASY03210.1 NsoR1 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 34.0 97.0 139.0 1.59e-40
QKW60381.1 response_regulator_transcription_factor BGC0002288.2 NRPS:Type I 38.0 99.1 139.0 2.39e-40
WP_078621122.1 response_regulator_transcription_factor BGC0002000.4 PKS 36.0 101.7 139.0 4.09e-40
CAD91201.1 putative_response_regulator BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 41.0 96.6 136.0 1.16e-39
BAJ07866.1 putative_repressor-response_regulator BGC0000232.5 PKS 37.0 95.3 137.0 1.52e-39
WP_237282926.1 response_regulator_transcription_factor BGC0001596.3 PKS:Type II aromatic 39.0 95.3 136.0 3.19e-39
CCH32754.1 Transcriptional_regulator BGC0002070.3 PKS 38.0 94.8 135.0 8.92e-39
WP_002554192.1 heavy_metal_response_regulator_transcription_factor BGC0002571.2 NRPS:Type I 37.0 94.8 134.0 8.93e-39
AAB91594.1 SpaR BGC0000559.4 ribosomal:RiPP:Lanthipeptide 34.0 97.0 134.0 9.89e-39
AVO00817.1 May18 BGC0001661.5 PKS 37.0 97.8 134.0 1.1e-38
AEK64499.1 EtnR BGC0000506.4 ribosomal:RiPP:Lanthipeptide 34.0 97.0 133.0 1.97e-38
AHW57766.1 PgaR1 BGC0000262.5 PKS:Type II+saccharide:hybrid/tailoring 38.0 95.7 134.0 2.15e-38
QYC40300.1 Response_regulator BGC0002344.2 NRPS:Type I 39.0 96.6 133.0 2.56e-38
ABB69091.1 hypothetical_protein BGC0000260.3 PKS 35.0 98.7 134.0 3.23e-38
BAC79018.1 repressor-response_regulator BGC0000245.5 PKS 37.0 100.0 133.0 3.26e-38
AQZ69221.1 DNA-binding_response_regulator BGC0001635.4 NRPS:Type I+PKS 40.0 96.6 132.0 3.61e-38
AFI57015.1 QmnRg3 BGC0000133.5 PKS 39.0 96.1 130.0 4.58e-37
QDG00829.1 two-component_system_response_regulator BGC0002028.4 PKS 36.0 96.1 130.0 7.41e-37
AZF85922.1 DNA-binding_response_regulator BGC0001963.2 PKS:Type I 35.0 98.3 129.0 7.76e-37
QDG00834.1 two-component_system_response_regulator BGC0002028.4 PKS 35.0 97.4 131.0 2.03e-36
OWA25481.1 DNA-binding_response_regulator BGC0001438.5 PKS+saccharide:hybrid/tailoring 34.0 100.0 128.0 3.35e-36
ALJ99857.1 FlsR1 BGC0001904.2 PKS:Type II aromatic 38.0 90.1 126.0 6.94e-36
QHZ32185.1 sensory_transduction_protein_regX3 BGC0002047.2 PKS 35.0 97.4 127.0 1.22e-35
CAB93669.1 RumR_protein BGC0000545.5 ribosomal:RiPP:Lanthipeptide 35.0 96.1 126.0 1.34e-35
POM23776.1 Transcriptional_regulatory_protein_SrrA BGC0002369.2 PKS 35.0 95.3 125.0 2.52e-35
AAK06808.1 putative_regulator_SimReg1 BGC0001072.5 PKS:Type I+saccharide+other:aminocoumarin 35.0 99.6 126.0 2.95e-35
AAL15573.1 putative_response_regulator BGC0000511.5 ribosomal:RiPP:Lanthipeptide 33.0 97.0 125.0 3.76e-35
ARO44672.1 positive_regulation_regulator BGC0001769.5 PKS 33.0 95.7 125.0 4.47e-35
MBW8699708.1 Transcriptional_regulatory_protein_YycF BGC0002140.2 PKS 33.0 95.7 125.0 4.47e-35
AAL15604.1 Sim1 BGC0000270.5 PKS 35.0 98.7 124.0 1.63e-34
ADI71440.1 putative_transcriptional_regulator BGC0000203.3 PKS 36.0 97.0 123.0 2.37e-34
BAG71485.1 response_regulator BGC0000536.3 ribosomal:RiPP:Lanthipeptide 29.0 98.7 122.0 3.61e-34
BAV17023.1 putative_transcriptional_regulator BGC0001384.5 PKS 32.0 95.7 122.0 1.11e-33
ALK27911.1 putative_two_component_transcription_regulator BGC0001233.5 NRPS:Type I 38.0 96.6 120.0 2.12e-33
AGS77305.1 Two_component_response_regulator BGC0001178.5 NRPS:Type I 35.0 96.6 119.0 5.84e-33
ADJ56358.1 NisR BGC0000535.4 ribosomal:RiPP:Lanthipeptide 29.0 98.7 119.0 1.1e-32
AGO50631.1 positive_regulation_regulator BGC0000229.5 PKS:Type II+saccharide:hybrid/tailoring 32.0 95.7 119.0 1.34e-32
AZM50118.1 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 38.0 96.1 118.0 1.65e-32
ASY03216.1 NsoR2 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 31.0 96.1 118.0 1.83e-32
OKI81334.1 transcriptional_regulator BGC0002478.3 PKS 32.0 98.7 118.0 2.72e-32
TRO56970.1 response_regulator_transcription_factor BGC0002361.3 PKS+saccharide 35.0 97.0 118.0 4.96e-32
AWR88437.1 putative_response_regulator BGC0001522.5 PKS 36.0 98.3 116.0 9.13e-32
CAE53348.1 response_regulator BGC0000440.5 NRPS:Type I 34.0 96.6 116.0 1.14e-31
CAG15007.1 two_component_response_regulator BGC0000441.4 NRPS:Type I 34.0 96.6 116.0 1.14e-31
CAH10125.1 putative_repressor-response_regulator BGC0000268.5 PKS 34.0 97.0 117.0 1.52e-31
AAM80541.1 VanRst BGC0000290.5 NRPS:Type I 35.0 95.7 115.0 2.55e-31
ADB02841.1 AzicR3 BGC0000202.5 PKS 33.0 100.4 113.0 1.33e-30
AOT85874.1 response_regulator BGC0001789.3 ribosomal:RiPP 30.0 97.8 113.0 1.43e-30
CCC21118.1 two_component_transcriptional_regulator BGC0000171.5 PKS:Type I 36.0 97.8 113.0 2.11e-30
CAG25752.1 putative_two-component_system_response_regulator BGC0000311.6 saccharide+NRPS:Type I 34.0 96.1 112.0 2.39e-30
ABA00873.1 NsuR BGC0000537.3 ribosomal:RiPP:Lanthipeptide 27.0 97.4 112.0 3.98e-30
AEX55159.1 putative_response_regulator_SlvR BGC0000549.3 ribosomal:RiPP:Lanthipeptide 27.0 98.7 112.0 5.08e-30
AKA59107.1 two-component_system_regulator BGC0001619.5 PKS 32.0 97.8 105.0 1.7e-27
QUS58949.1 response_regulator_transcription_factor BGC0002123.3 NRPS:Type I+PKS:Trans-AT type I 31.0 96.1 104.0 3.83e-27
CQR60474.1 Transcriptional_regulator,_atypical_response_regulator BGC0001287.5 PKS 33.0 92.7 99.0 7.41e-25
CAD91233.1 hypothetical_protein BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 43.0 52.6 95.0 2.4e-24
DMB38_33825 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 45.0 51.3 92.0 3.22e-23
AGG35708.1 two-component_system_response_regulator BGC0000883.5 other:other 43.0 52.6 92.0 4.54e-23
CYV09491.1 NisR BGC0002575.2 ribosomal:RiPP 26.0 96.6 94.0 5.48e-23
QXJ26481.1 response_regulator BGC0002370.2 NRPS:Type I 44.0 46.6 87.0 1.31e-21
AHI58828.1 WelR3 BGC0000668.5 terpene:Monoterpene+other:other 40.0 47.4 89.0 2.1e-20
ABK32284.1 Jer4 BGC0000080.5 PKS 36.0 70.3 83.0 3.94e-18
ABK32252.1 Amb4 BGC0000014.5 PKS 35.0 70.3 81.0 1.83e-17
AAZ23070.1 possible_response_regulator BGC0000291.5 NRPS:Type I 31.0 89.2 74.0 1.04e-15
CAL80818.1 two-component_hybrid_sensor/regulator BGC0000997.4 NRPS:Type I+PKS 35.0 53.0 70.0 1.99e-13
AFL68048.1 response_regulator_with_CheY-like_receiver_domain_and_winged-helix_DNA-binding_domain BGC0001524.3 NRPS:Type I+PKS 37.0 45.3 66.0 1.1e-12
AKA59096.1 LuxR-family_response_regulator BGC0001619.5 PKS 30.0 88.4 66.0 1.21e-12
QDF63356.1 KyaR BGC0002346.3 ribosomal:RiPP 32.0 87.1 66.0 1.21e-12
ABB05090.1 LipReg1 BGC0001003.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 30.0 90.1 65.0 2.57e-12
QBK47604.1 CebA BGC0002316.2 ribosomal:RiPP 36.0 50.4 65.0 2.91e-12
AUA09456.1 Transcriptional_regulatory_protein_LiaR BGC0002291.3 PKS 29.0 90.1 65.0 3.24e-12
CAB38597.1 two_component_system_response_regulator BGC0000315.5 NRPS:Type I 30.0 78.9 64.0 6.51e-12
QUQ72331.1 response_regulator_transcription_factor BGC0002349.3 PKS:Type I 33.0 50.4 64.0 7.11e-12
ALV82366.1 regulator BGC0001370.4 NRPS:Type I 30.0 78.9 63.0 8.96e-12
AEG64693.1 two_component_system_response_regulator BGC0000379.5 NRPS:Type I 36.0 50.9 63.0 1.31e-11
CAF05631.1 hypothetical_protein BGC0001053.5 NRPS:Type I+PKS 30.0 51.3 64.0 1.58e-11
QWT72285.1 response_regulator_transcription_factor BGC0002430.3 NRPS:Type I+saccharide 31.0 78.4 62.0 1.63e-11
ctg1_orf18 BGC0000053.5 PKS 28.0 91.8 62.0 2.27e-11
AHX24716.1 LuxR_family_transcriptional_regulator BGC0000200.5 PKS:Type II+saccharide:hybrid/tailoring 30.0 72.4 62.0 2.47e-11
ADB02831.1 AzicR2 BGC0000202.5 PKS 30.0 69.8 61.0 3.96e-11
BBD82049.1 LuxR_family_transcriptional_regulator BGC0001920.4 ribosomal:RiPP 28.0 101.3 61.0 6.15e-11
WP_122215947.1 response_regulator_transcription_factor BGC0002015.4 ribosomal:RiPP 28.0 102.6 61.0 8.53e-11
BCD33686.1 bacterial_regulatory_proteins,_luxR_family BGC0002448.2 NRPS:Type I 33.0 50.4 60.0 1.06e-10
SFF02396.1 two_component_transcriptional_regulator,_LuxR_family BGC0001674.5 ribosomal:RiPP 28.0 101.3 60.0 1.58e-10
WP_030193597.1 response_regulator_transcription_factor BGC0002669.2 ribosomal:RiPP 33.0 65.1 59.0 1.91e-10
AXO35193.1 DNA-binding_response_regulator_LuxR_family BGC0001848.4 other:other 33.0 51.7 58.0 7.28e-10
QHZ32201.1 response_regulator_transcription_factor BGC0002307.3 ribosomal:RiPP 26.0 91.4 58.0 7.6e-10
EWM63043.1 two-component_system_response_regulator BGC0000679.5 terpene 33.0 51.7 57.0 9.96e-10
QBC75031.1 DNA-binding_response_regulator BGC0001968.3 NRPS:Type I 29.0 73.7 57.0 1.25e-09
ADC45530.1 two-component_system_response_regulator BGC0000093.5 PKS:Type I 35.0 52.6 57.0 1.51e-09
AQP25576.1 LuxR_family_response_regulator BGC0001590.5 PKS:Type II aromatic 31.0 50.0 57.0 1.86e-09
AAZ23059.1 probable_putative_response_regulator BGC0000291.5 NRPS:Type I 28.0 90.9 57.0 2e-09
ACI88885.1 AlnR6_two_component_response_regulator BGC0000195.5 PKS:Type II 34.0 50.0 56.0 2.49e-09
ABL09961.1 regulator BGC0000197.5 PKS:Type II+saccharide:hybrid/tailoring 31.0 70.3 56.0 2.84e-09
AAU34214.1 two_component_response_regulator_MppU BGC0000388.5 NRPS:Type I 25.0 98.3 56.0 4.84e-09
ARF06225.1 LuxR_family_transcriptional_regulator BGC0001593.5 NRPS:Type I 33.0 54.7 54.0 1.41e-08
BAW35603.1 putative_DNA-binding_response_regulator BGC0002357.3 PKS+other:other 26.0 88.4 52.0 5.14e-08
ATD51275.1 two-component_system_response_regulator BGC0001650.4 NRPS:Type I 34.0 53.4 52.0 5.4e-08
QWF78530.1 Transcriptional_regulatory_protein_LiaR BGC0002142.2 PKS 29.0 49.6 52.0 7.83e-08
ACX83628.1 putative_two-component_response_regulator BGC0000221.5 PKS 31.0 50.9 51.0 1.45e-07
EHK80177.1 two-component_system_response_regulator BGC0001447.3 PKS 32.0 50.0 51.0 1.8e-07
BAW27696.1 regulator BGC0001764.4 NRPS:Type I 26.0 88.8 51.0 1.97e-07
EAW09112.1 sensor_histidine_kinase/response_regulator,_putative BGC0000983.5 NRPS:Type I+PKS:Iterative type I 26.0 56.9 51.0 3.67e-07
CAN02021.1 putative_two-component_system,_response_regulator BGC0000528.5 ribosomal:RiPP:Lanthipeptide 31.0 50.9 50.0 3.68e-07
QDQ37907.1 two-component_system_response_regulator BGC0001979.4 PKS 28.0 70.3 50.0 4.16e-07
BBA21064.1 putative_two-component_response_regulator BGC0001740.5 NRPS:Type I+PKS 35.0 37.9 47.0 9.98e-07
ACI88882.1 AlnR5_two_component_response_regulator BGC0000195.5 PKS:Type II 28.0 70.3 49.0 1.03e-06
AKT74265.1 TxnRg4 BGC0002141.3 PKS 25.0 94.0 48.0 1.42e-06
MCG7203797.1 response_regulator_transcription_factor BGC0000248.5 PKS 28.0 70.7 46.0 6.49e-06