LOCUS       NZ_CP102512            21131 bp    DNA     linear   CON 11-FEB-2024
DEFINITION  Streptomyces sp. CA-210063 chromosome, complete genome.
ACCESSION   NZ_CP102512
VERSION     NZ_CP102512.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CA-210063
  ORGANISM  Streptomyces sp. CA-210063
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10859970)
  AUTHORS   Nielsen,J.B., Gren,T., Mohite,O.S., Jorgensen,T.S., Klitgaard,A.K.,
            Mourched,A.S., Blin,K., Oves-Costales,D., Genilloud,O., Larsen,T.O.,
            Tanner,D., Weber,T., Gotfredsen,C.H. and Charusanti,P.
  TITLE     Identification of the Biosynthetic Gene Cluster for Pyracrimycin A,
            an Antibiotic Produced by Streptomyces sp
  JOURNAL   ACS Chem Biol 17 (9), 2411-2417 (2022)
   PUBMED   36040247
REFERENCE   2  (bases 1 to 10859970)
  AUTHORS   Joergensen,T.S., Gren,T., Blin,K. and Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2022) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 05-AUG-2022
            Assembly Method :: Flye v. 2.9-b1768; Polypolish v. 0.5.0; POLCA
            polisher from MaSuRCA v. 4.0.5
            Assembly Name                     :: M642_aaa1.6.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 55.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 11:12:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,501
            CDSs (total)                      :: 9,410
            Genes (coding)                    :: 9,051
            CDSs (with protein)               :: 9,051
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 359
            CDSs (without protein)            :: 359
            Pseudo Genes (ambiguous residues) :: 0 of 359
            Pseudo Genes (frameshifted)       :: 141 of 359
            Pseudo Genes (incomplete)         :: 302 of 359
            Pseudo Genes (internal stop)      :: 23 of 359
            Pseudo Genes (multiple problems)  :: 101 of 359
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:19:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9651543
            Orig. end                         :: 9672674
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102512.1.
            Bacteria and source DNA available from Tilmann Weber, Dr.
            Professor, Novo Nordisk Foundation Center for Biosustainability,
            Kemitorvet, 220, 327D 2800 Kgs. Lyngby, Denmark.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21131
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="32"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21131
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21131
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11131](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11131)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(374..958)
                     /locus_tag="JIX56_RS42335"
                     /old_locus_tag="JIX56_42335"
     CDS             complement(374..958)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474918.1"
                     /locus_tag="JIX56_RS42335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42335"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_257549038.1"
                     /transl_table=11
                     /translation="MRQKKDSPLRSDAQRNRERILAVALTELTRSADAPLSRIARKACV
                     GQGTFYRHFPNREALVLEVYRFEIRQVADAAAELLATREPDRALREWMDRLALFAMAKA
                     GLADAIRQAISGLSAPDRPGHAPVSEAAELLLRAGEKAGTIRPGVTHEDFFLAIAGLWQ
                     IDPQQDWQPRATRLLDLVMDGLRTGAPGTEK"
     gene            1200..1766
                     /locus_tag="JIX56_RS42340"
                     /old_locus_tag="JIX56_42340"
     CDS             1200..1766
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474916.1"
                     /locus_tag="JIX56_RS42340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42340"
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="WP_257549039.1"
                     /transl_table=11
                     /translation="MSPATSSTYSAITLNINGEKHTLSVDHRTTLLDALRERLDLTGTK
                     KGCDQGQCGACTVLVDGRRNVSCLQLAVAAEGREITTIEGVAEGERLHPVQQAFLDLDG
                     YQCGYCTPGQICSAIAVIEEHAAGWPSAVTDDVRPEATPPPLSAEEIRERMSGNLCRCG
                     AYVSIVEAVARAAADTTAKSKEAVA"
     gene            1763..2755
                     /locus_tag="JIX56_RS42345"
                     /old_locus_tag="JIX56_42345"
     CDS             1763..2755
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027599.1"
                     /locus_tag="JIX56_RS42345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42345"
                     /product="xanthine dehydrogenase family protein subunit M"
                     /protein_id="WP_257549041.1"
                     /transl_table=11
                     /translation="MREFDYRRAYDVSGAVALLGADPEARFLGGGTNLVDLMKSGVERP
                     ARLVDVRELPLDGIEPTEDGGLRIGATVTNSDLAAHPEVRRRYPALTQAVLAGASGQLR
                     NMATVGGNLLQRTRCGYFADVTKPCNKRVPGSGCPAIEGEHHNHAILGASEHCVATHPS
                     DMGVALTAFDAVVTYETADGPGELPFADFYLPVGDTPHIETALPPGALITGVTLPPAEV
                     AAHSRYRKVRERASYAFAIGSIAAALDVQDGVVREVRLAFGAVASRPWRAYAAERALTG
                     APADAETFAAAADAELAEAKPLPHNGYKVPLMRNLVVAVLSELTEEATR"
     gene            2752..4872
                     /locus_tag="JIX56_RS42350"
                     /old_locus_tag="JIX56_42350"
     CDS             2752..4872
                     /GO_function="GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1293: aldehyde oxidase and xanthine dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005607.1"
                     /locus_tag="JIX56_RS42350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42350"
                     /product="xanthine dehydrogenase family protein
                     molybdopterin-binding subunit"
                     /protein_id="WP_257549042.1"
                     /transl_table=11
                     /translation="MTIAPTAHKGAVGTAHTRVEGRDKVTGAARYAGEIPFAGLVHGWL
                     ALSTVARGRIRAIETADALGMPGVLSVLTHENAPRVDTDYTGLMGTKPDPTTAVFQHDR
                     VPHLGWPVALVVAETSEQAREAAEALVVHYEQEPHDVAFAAEHPDAYALDTFGPAVIEK
                     GDLGAELAASAVVLDAEYTTPEEHHNPMEPHAVTARWDGGRLEVVDSNQGTMWVAGELA
                     NLFSLDPASVRVLSEHVGGGFGSKGVRAHQVAAVMAATVLRRPVRVVMTRRQMFSLAGY
                     RSPTTQRVRLGADADGRLRALEHRSQSLTSTVHEFIEPGAGPARVMYDADAHHTANKVV
                     RLDVPTPTWMRAPGEAPGSFALESAFDELAEKLGIDPIELRARNEPERGPVSGLPFASR
                     RLHACFREGAGRFGWADRDPRPGLRRDGRWLLGTGTAAASFGAGAAPSTAGVTAEADGT
                     FTVRVNAADIGTGARTALTLVAADALEVAPERVRVRIGDSDFGPAMIAGGSMGTRSWAW
                     AVTAAATELRERLVLSDGIPPEGIMVRSDTTAAIGALAQKERHSYGAQFAEVAVDPATG
                     EVRVRRMLGIFAAGRIVNPLTARSQFIGGMTWGISMALHEEAVRDQASGGHYGADLAGY
                     HVAAHADVPAIEADWVDDPDPDDPVGIKGIGEIGIVGAAAAVANAVWHATGVRHRHLPI
                     RPDRVLMAGRDA"
     gene            4865..6082
                     /locus_tag="JIX56_RS42355"
                     /old_locus_tag="JIX56_42355"
     CDS             4865..6082
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474912.1"
                     /locus_tag="JIX56_RS42355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42355"
                     /product="XdhC/CoxI family protein"
                     /protein_id="WP_257549043.1"
                     /transl_table=11
                     /translation="MLDLATELSAWAEEGRDFAVATVVAVSGSAPRGPGAALAVDSEGT
                     AIGSVSGGCVEGAVYELCQQALADGETVLQRFGYSDEDAFAVGLTCGGVIDILVTPVTA
                     RSPARAVLSAALSAACKDEPTAVARVVRGPAELLGQALLVRPAGSREQGDSGVGVGSYE
                     GGLGGHPELDRTAAAEARAMLDSGRTGTIELSASGARWGSPRTESGGGSHCSGGLTLLV
                     ETRVPPPRMIVFGAIDFAAALVRAGKFLGYHVTVCDARPVFATRTRFPEADDIVVDWPH
                     RYLRRTETDSRTVLCVLTHDAKFDVPLLKTALRMPVAFVGAMGSRRTHADRDRRLREVG
                     LTDGELARLRSPIGLDLGARTPEETALSIAAEIVATRRGGTGVPLTGSGTPIHREAGER
                     GAVAAA"
     gene            6153..6476
                     /locus_tag="JIX56_RS42360"
                     /old_locus_tag="JIX56_42360"
     CDS             6153..6476
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044328.1"
                     /locus_tag="JIX56_RS42360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42360"
                     /product="hypothetical protein"
                     /protein_id="WP_257549044.1"
                     /transl_table=11
                     /translation="MDTHTSRPRPLRNVTATATATGSALAVALLPLVVGALVARSVGGD
                     PMASVNALIAGGGERAKLCRSQLPVLRRIRRTGSRTGRHPALRRLLAGREDVRVEVPHG
                     RER"
     gene            complement(6420..7805)
                     /locus_tag="JIX56_RS42365"
                     /old_locus_tag="JIX56_42365"
     CDS             complement(6420..7805)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313586.1"
                     /locus_tag="JIX56_RS42365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42365"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_257549045.1"
                     /transl_table=11
                     /translation="MSLTRTRTRARARARALCTVAALALGVPVAFSGPAVAAVPTYAVY
                     LQNSVTGLNAADNGGTVAAHNPKGNEDHQQWTPVAVSGGHQLRNADESGICLGRGGTSA
                     VTTTCGADGTTWTITEAANSTYTIGVPGTSQYLTGASSDSSVVQIGSSGTYARWYLTPV
                     TYATTAMPSTDTRTLDQVSFLTSHNAYANGVDGNFASFPVSLFPNQSRGVAQQLTDGVR
                     GFMLDAYTVSGQAVLCHNSCDGVSSPVPLATDLQRMVDFLEAHPGEVVTVFLEDYTASD
                     ILKSSLASVSGLSDVLYRPDQEGVATSGWPTMADLAARGKQLLIFSDRTRASDVSSGYT
                     TRDTFGVMYQREWTVENYWSMGGGIGDSDWSCYSRWGTSRPLTTDSPAFHPLFVMNHFR
                     DYTVSGTAETDNAKLLNRAQTFCTPAARKKPNYLAVDRYDLGSPSPLTTVGNLNTYVLT
                     AGQ"
     misc_feature    7957..7972
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 20.59"
                     /tool="antismash"
     gene            7994..8944
                     /locus_tag="JIX56_RS42370"
                     /old_locus_tag="JIX56_42370"
     CDS             7994..8944
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386733.1"
                     /locus_tag="JIX56_RS42370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42370"
                     /product="peptidoglycan-binding domain-containing protein"
                     /protein_id="WP_257549047.1"
                     /transl_table=11
                     /translation="MSEPTAPVCPQCGTPRATDGTPACSCGRLASDAHRDTRTAQAEAV
                     EDFDPVRIRPFVKVGDDTEPADSSADSSADAEGTPEPGPLKDGDEPPLPGGSTGGTPAL
                     LDLDERPPVDSDPGGQRRRRRAVSAAGVGVAAVAVLVTGGIIGGLFSYDGPSRDGSGPE
                     DIRANLPEAAPGQEASSSSASPSGTASSASPSGNPSTSPAATPTESRTTPTGSATPTRT
                     PSNSGSTATAAPAPTPSDSQDPVLGTGDSGPEVTELQLRLRQIGFYNGVIDGDYDPEVE
                     SAVRGYQLTRVVVEDESGVYGPATRTSLESETTEP"
     gene            complement(9051..9917)
                     /locus_tag="JIX56_RS42375"
                     /old_locus_tag="JIX56_42375"
     CDS             complement(9051..9917)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574303.1"
                     /locus_tag="JIX56_RS42375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42375"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_257551439.1"
                     /transl_table=11
                     /translation="MPAQPPTSSPARSTYQNRVADYWNAEENPVNLELGKIDDLYHHHY
                     GIGDADWSVLDDDPDPARRRDRVTAELHRLEQAQADLLAHHLGPLSPTDRVFDAGCGRG
                     GGSVVAHLRYGCQADGVTISRKQAEFANEQARKRDIDDRVRYHHRDMLDTGLPSGEYAA
                     SWNNESTMYVELDLLFAEHARLLRRGGRYVTITGCYNDTYGRASREVSLINAHYICDIH
                     PRSEYFRAMARNRLVPVHVVDLTAAALPYWELRKQADHLVTGIEDTFITAYENGSFQYL
                     LIVADRV"
     gene            complement(10001..11131)
                     /locus_tag="JIX56_RS42380"
                     /old_locus_tag="JIX56_42380"
     CDS             complement(10001..11131)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031839.1"
                     /locus_tag="JIX56_RS42380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42380"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_257549048.1"
                     /sec_met_domain="T1TS (E-value: 1.3e-53, bitscore: 182.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASAGPPSPAVTSAGLPSADLPSPGLPSVCAPARRRLPGPPSPAR
                     SRRARGGGAIPGLRYRPAVPADPAKAAEVDRRLEAWAERMDLFPREWRGQFARFGLGRA
                     IVLAHPGAAGPEHLTAAGKLLLAEHLVDNLYCEVDEGKGGSPRGLGGRLLMAQSALDPL
                     HSTPEVENRWRHGVRGDGPLRSYHFALRDYAALATPSQTDRLVHDLARLHLGYLGEAAW
                     AETDHMPRIWEYLVMRQFNNFRPCLAIVDAVDGWELPEAVYARPEVQRITALAGNASTI
                     VNDLYSFTKEMSNDPDHLNLPMVIAANERCGLKAAYLEAVEIHNRIMEAFEEESAALSA
                     TSPLIERYATALAAWVAGNHEWHATNTDRYSLPDYW"
     gene            complement(11260..12687)
                     /locus_tag="JIX56_RS42385"
                     /old_locus_tag="JIX56_42385"
     CDS             complement(11260..12687)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005613.1"
                     /locus_tag="JIX56_RS42385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42385"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_257549049.1"
                     /transl_table=11
                     /translation="MTAPVSSSESAPEPADAQQFTSLSTRAARQLATTTKSEPQMQAIT
                     SRWLLKTLPWVDVKGGTYRVNRRLQLRIGRGRVQFDQNGADDVKVIPETLTELPALRGY
                     SDIPALREISSRFRVREVRAGQVLVDAGQPVTEAYLVVHGRFTRYTIGKYGEEEVLGLL
                     TDGDGLGDEAIGHADPLWLSSVRAETAGVVLALNWDALMAFVERTPSLAAQFDAFADRQ
                     RKPMNRKGEADVPLEAGHVGELALPGGFVDYDLAPREYELSLTQTVLRVHTRVADLYNH
                     PMDQTEQQLRLTIEEIRERQEWELVNNREFGLLHNIDYGQRISTFSGPPTPDDMDELLS
                     MRRKTRLYLAHPKAIAAFFRQCNRRGLVPGTVNVDGHEVPAWRGVPLFPCSKIPITPQH
                     TTSIIALRTGEKDQGVVGLHQTGIPEEYEPSLNVRFMGVDTTAIMSYLVTAYYSLAVLV
                     PDAAGILENVQVGWMPE"
     gene            complement(13111..14370)
                     /locus_tag="JIX56_RS42390"
                     /old_locus_tag="JIX56_42390"
     CDS             complement(13111..14370)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326608.1"
                     /locus_tag="JIX56_RS42390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42390"
                     /product="glucarate dehydratase family protein"
                     /protein_id="WP_257549050.1"
                     /transl_table=11
                     /translation="MTGTPGTRIRELIVTPIAFRDPPLLNSSGVHEPLALRTILQLVLE
                     DGTVGLGESTGGTVRLERLEAAAKAVVGLDVFDTTAVSAAIDAVLLPTVPSSHERGWTT
                     SVVEVACLDAQGKLLGRPVSDLLGGRVRDSVPFAAYLFYKWAEHPALDGRPAVGDDWGE
                     ALDPAGVVEQARLMRQRYGFRSFKLKGGVFPPDEEIAAIKALAEAFPGQPLRLDPNTAW
                     TVETSKYVARELDGVLEYLEDPTATIPGMAEVAKDAPMPLATNMCVVAWEHLRPAIERD
                     AIQVLLTDHHYWGGLRRTRELAAVCEAFGIALSMHSNSHLGISLAAMTHVAAAIPHLDH
                     SCDTHYPWNSADDVIVPGVLEFRDGEVAVPTGPGLGVELDHDALGRLHRLYVDSGMRSR
                     DDTGYMRRIQPGYELRLPRW"
     gene            complement(14435..15343)
                     /locus_tag="JIX56_RS42395"
                     /old_locus_tag="JIX56_42395"
     CDS             complement(14435..15343)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326609.1"
                     /locus_tag="JIX56_RS42395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42395"
                     /product="5-dehydro-4-deoxyglucarate dehydratase"
                     /protein_id="WP_257549051.1"
                     /transl_table=11
                     /translation="MKFQGVLFFPVTPFASDGSLDEERLAQHIEAGVAAGAGGVFVACG
                     TGEFHALTPEEIERATRVAVTVTAGRVPVLAAAGGPPPVARDQAARVERAGADGILLLP
                     PYLVSAPQRGLVRYVEEVTAATGLPVIFYQRGTARLTADTAAEIATLPGVVGLKDGIGD
                     IERMHRIVRAVRAVPGTEGFQFFNGLPTAEMTAPAYRGIGVGLYSSAVFAFAPEIALAF
                     HRALADGDEALVSTLLDEFYGPLVELRDEVPGYAVALIKAGVTLRGLDVGGVRAPLIDP
                     APEHVSRLAKLIDHGLGVVGA"
     gene            complement(15373..16326)
                     /locus_tag="JIX56_RS42400"
                     /old_locus_tag="JIX56_42400"
     CDS             complement(15373..16326)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380209.1"
                     /locus_tag="JIX56_RS42400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42400"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_257549052.1"
                     /transl_table=11
                     /translation="MSAPALDPVRTPSSDEAVASSGRAGKRARTTPARFDTALGWNDRP
                     GVSWALRILLCATALGIFAAPFLTIVSGALSTHPSGSSLSFLPHDSTLLNFRVAGERGI
                     WDYFTNSLVIAGGGLLLQLVVCVLAAYALARHRFRGQAIVMTLFMLTMMLPEEVIAIPL
                     SLVLGHVPVVGIDLKGTVWGVILPLGAWGFSVMLLTEFMKDIPGEIEEAARLDGVGELR
                     MLWQVVLPLCRPALGVAGVLGFIMIWDQYLLPLIAAKDPTDYTVTVALSILRTDPEVGS
                     GVVLAGAVIALLPSLVVYLLLQRSLVTGIAAGATKG"
     gene            complement(16323..17243)
                     /locus_tag="JIX56_RS42405"
                     /old_locus_tag="JIX56_42405"
     CDS             complement(16323..17243)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326610.1"
                     /locus_tag="JIX56_RS42405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42405"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_257549053.1"
                     /transl_table=11
                     /translation="MTATTIAPRRRGALTKRVFGKKAVLPWLFLAPGLLLALVFKFLPM
                     GKGIWLSFFDVRPFLGDQWVGLDNYTRVLTDHRFQDAVGHTLLLGIGQSLGAIVVGFFL
                     ALLLEGQARSLKIMRTAVFLPVVTATAVVGELWRLMYYPTSDGLVNSALGFLGLGPTPF
                     LDNPDTALWATMVMGIWMVAPYNMVIILAGLAGVDRTLYEAAAMDGVSLWQRLRHVTLP
                     AIRPAIGIVLTLAAIRGLRVFTEVYVLTGGGPAGSTEVWMTRAYTLGFTRNDIGGASAA
                     SVVLLAVTLLLTVTVNHFRKRGDVR"
     gene            complement(17240..18565)
                     /locus_tag="JIX56_RS42410"
                     /old_locus_tag="JIX56_42410"
     CDS             complement(17240..18565)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380201.1"
                     /locus_tag="JIX56_RS42410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42410"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_257549055.1"
                     /transl_table=11
                     /translation="MGVRRRSHRLAAMITVAGLAFGAAGCGSGSDSAGGDDPNTLEVWT
                     RSNPDPAATYERVFAAFTEKTGIKIDYQPVINFDQQLQSRASTRDLPDVMINDTALMGS
                     YQSQGLLETIDPAAIEGHDQITDKTWSSTVGIDGEHYGIPYSRQAQTLMIRKDWLRKLG
                     LQAPTTWAEMIGVAKAFADRDPDGDGKKDTYGMVVPGSAQNGYAAWWGASFLWSGGAKI
                     IEPDGKGYRPAMDSAAAVRTVTWMKDNLFCGDNGVIQPGAITAVTGTATNFQDGDAGMY
                     LTGPYNIATYDATPGKDTFDVVPFPAGPAGSTVLADGENIYFGARTGKTRQEQALAAFL
                     ISPEGQKLAMTGDNQPVVRIPVNSTLDAAQVRDDPRWSVVQKAYEDASEQFPNAPDFAP
                     IKQDTADALNAVFTYCGSDVGSSLKELNDTLAGDLKDQDLLK"
     gene            18767..19630
                     /locus_tag="JIX56_RS42415"
                     /old_locus_tag="JIX56_42415"
     CDS             18767..19630
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640663.1"
                     /locus_tag="JIX56_RS42415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_42415"
                     /product="fructosamine kinase family protein"
                     /protein_id="WP_257549056.1"
                     /sec_met_domain="APH (E-value: 3.8e-12, bitscore: 45.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDRTAPGALAARLTGRPATGERRLSGTLAEVTLDDGRVVLVKLG
                     DGPGAAQAEAAGLRWLAEAGTVRVPTLYGHDKGRLVIDRVAQGAPSAAAATRFGAALAV
                     LHATGAPSFGAPPPGGPREAYIGRAPMRNLPGTDWPAWYAEHRVLPYLRRAVDDGTIRP
                     AEAPLIEDVCDRLPDLAGPAEPPARLHGDLWNGNVLWGADGHTWLIDPAAHGGHRETDL
                     AMLALFGCPHLGHILDGYQRAAPLADGWADRIGLHQLFPLLVHAVLFGRGYAEQALAVA
                     RATLTW"
     misc_feature    19744..19764
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.56"
                     /tool="antismash"
     misc_feature    complement(19834..19849)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.75"
                     /tool="antismash"
ORIGIN
        1 ggcgggttca tcgacaacgc caacccgggc gcactggtgg ccgagcgctg cacggcgtgg
       61 cgcaacaagg gcaccggatt cgacttcgcc gacgccgacg gcacactgac gaagaacctg
      121 gcggtggcca acgggacgaa tgtctcgctg ggctcgaact ccggtggcag cggcaactcc
      181 tggaacctcg gcggcacctg gtccttcgtg agcaccgacg cggccacgat caccggggcc
      241 agggcggccg acggctccct cccggcctcg cacttcctgc gccccgcgaa cggcgcggac
      301 gtcggggcgc ggctctgacg aaaggccctt gcccggtgtt cctcgtgcgc cgcccggccg
      361 gaccgggcgg cgctcatttc tccgttcccg gtgccccggt acgcaggccg tccatgacga
      421 ggtcgaggag gcgggtggcg cgcggctgcc agtcctgctg ggggtcgatc tgccagaggc
      481 cggcgatggc gaggaagaag tcctcgtggg tgactccggg gcggatggtt ccggccttct
      541 cgcccgcgcg gagcagcagt tcggcggcct cgctcaccgg ggcgtgcccc ggcctgtccg
      601 gggcgctcag gccgctgatg gcctggcgga tcgcgtccgc gaggcccgcc ttggccatgg
      661 cgaacagggc gaggcggtcc atccactcgc ggagcgcccg gtccggctca cgggtcgcga
      721 gcagttccgc ggcggcgtcg gcgacctgcc gtatctcgaa ccggtagacc tccaggacga
      781 gcgcctcccg gttcgggaag tggcggtaga acgtgccctg cccgacacac gccttcctgg
      841 cgattctgct cagcggcgcg tccgcggagc gcgtcaactc ggtcagggcg actgccagga
      901 tgcgctcgcg gttccgctgc gcgtccgagc gcagagggga gtccttcttc tgccgcacgc
      961 gtcctcctca cgggttcatg gccgaaaccc gtccttgtta accggacaac tgtccgttac
     1021 gtttttccgg agaggacagc tgtccggttg gttcatcgta gcgtcggtgt ggccggcgcc
     1081 agtaccccgg ctgccccgca tccctgactc gaccgcctgc cggagcgcgt acctttttcc
     1141 ctgttttccc tgttcttcct gttttccctg tgtcccggat acgcgaaaga aggctgatca
     1201 tgtccccagc cacctcctcg acgtacagcg ccatcaccct gaacatcaac ggcgagaagc
     1261 acacgctctc cgtcgaccac cgcaccaccc tgctcgacgc gctgcgcgag cgactcgatc
     1321 tgaccggcac caagaagggc tgcgaccagg gacagtgcgg cgcctgcacc gtcctcgtcg
     1381 acggacgccg caacgtgtcc tgtctgcagt tggcggtggc ggccgaggga cgtgagatca
     1441 ccaccatcga aggtgtcgcc gagggcgagc gactccaccc ggtgcagcag gcgttcctcg
     1501 atctggacgg ctaccagtgc ggctactgca caccgggcca gatctgttcg gccatcgcgg
     1561 tcatcgagga gcacgcggcg ggctggccca gcgccgtcac cgacgacgtc cgccccgagg
     1621 cgacgccgcc acccctgagc gccgaggaga tccgggagcg gatgagcggc aacctgtgcc
     1681 gctgcggcgc ctacgtgtcg atcgtcgagg ccgtcgcccg cgccgccgcc gacaccacgg
     1741 cgaagtccaa ggaggccgtg gcatgaggga gttcgactac cggcgcgcgt acgacgtctc
     1801 cggcgccgtc gccctcctcg gcgccgaccc cgaggcccgt ttcctcggcg gcggcaccaa
     1861 cctcgtcgac ctgatgaaga gcggcgtcga gcggcccgcg cgcctcgtcg acgtccgcga
     1921 actcccgctc gacgggatcg agcccaccga ggacggcgga ctgcgcatcg gcgcgaccgt
     1981 caccaacagc gacctcgccg cccaccccga agtccggcgc cgctacccgg cgttgaccca
     2041 ggcggtgctg gccggcgcct cggggcagct gcgcaacatg gccaccgtcg gcggcaacct
     2101 gctccagcgc acccgctgcg gctacttcgc cgacgtcacc aaaccctgca acaagcgggt
     2161 gcccggcagc ggttgccccg cgatcgaggg cgagcaccac aaccacgcga tcctcggcgc
     2221 ctccgagcac tgcgtggcca cccacccctc cgacatgggt gtcgccctga cggccttcga
     2281 cgccgtcgtg acgtacgaaa cggccgacgg gccgggcgag ttgccgttcg ccgacttcta
     2341 tctcccggtc ggggacaccc cgcacatcga gacggccctg ccgccgggtg ccctgatcac
     2401 cggcgtgacc ctgccgcccg ccgaggtcgc cgcccactcc cgctaccgca aggtccgcga
     2461 gcgcgcctcg tacgccttcg ccatcggctc catcgccgcc gcgctcgacg tccaggacgg
     2521 tgtcgtacgc gaggtgcggc tggccttcgg ggcggtcgcg tcccggccgt ggcgggcgta
     2581 cgcggcggag cgggcgctga cgggggcgcc ggccgacgcc gagaccttcg cggccgccgc
     2641 ggacgccgaa ctggcggagg ccaagccgct gccgcacaac ggatacaagg tgccgctgat
     2701 gcgcaacctc gtcgtggccg tcctgtccga actcaccgag gaggccaccc gatgaccatc
     2761 gcccccacgg cacacaaggg cgccgtcggc accgcgcaca cccgcgtcga aggccgcgac
     2821 aaggtcaccg gagcggcccg ctacgcgggc gagatcccct tcgccggact cgtccacggc
     2881 tggctggcgc tgtccaccgt ggcccgcggc cggatccgcg ccatcgagac cgccgacgcg
     2941 ctcgggatgc cgggcgtgct cagcgtcctg acccacgaga acgccccgcg cgtcgacacc
     3001 gactacacgg gtctcatggg cacgaaaccg gacccgacca cggccgtctt ccagcacgac
     3061 cgggtgccgc acctgggctg gccggtcgcg ctggtcgtcg ccgagacctc cgagcaggcc
     3121 cgcgaggccg ccgaggcact cgtggtgcac tacgaacagg aaccgcacga cgtcgcgttc
     3181 gccgccgagc acccggacgc gtacgcgttg gacaccttcg gacccgcggt gatcgagaag
     3241 ggcgacctgg gggccgaact cgccgcgtcc gccgtcgtcc tggacgccga gtacaccacc
     3301 cccgaggaac accacaaccc gatggagccg cacgcggtga cggcccgctg ggacgggggc
     3361 cggctcgaag tcgtcgactc caaccagggc accatgtggg tcgcgggcga gctcgccaac
     3421 ctgttctccc tcgacccggc ctcggtgcgg gtcctctccg aacacgtcgg cggcggcttc
     3481 ggcagcaagg gcgtccgtgc ccaccaggtc gccgcggtga tggccgcgac cgtcctccgg
     3541 cgcccggtcc gggtcgtcat gacccggcgt cagatgttct ccctggccgg ctaccgcagc
     3601 cccaccaccc agcgggtcag gctcggcgcc gacgccgacg ggcggctccg cgccctggaa
     3661 caccgctccc agagcctcac ctcgaccgtc cacgagttca tcgagccggg tgccggaccg
     3721 gcccgcgtga tgtacgacgc cgacgcccac cacaccgcca acaaggtcgt acggctcgac
     3781 gtgcccaccc cgacgtggat gcgcgcgccg ggtgaggcgc cggggtcgtt cgccctggag
     3841 tcggcgttcg acgagctcgc cgagaagctg ggcatcgacc cgatcgagct gcgcgcccgc
     3901 aacgagcccg agcggggccc cgtctccggg ctgccgttcg ccagtcgccg tctgcacgcc
     3961 tgcttccgcg agggcgcagg caggttcggc tgggccgacc gcgacccgcg ccccggtctg
     4021 cgccgcgacg gccgctggct gctcggcacc ggcaccgccg cggcctcctt cggcgcggga
     4081 gccgccccct ccaccgccgg ggtgacggcc gaggcggacg gcaccttcac cgtgcgcgtc
     4141 aacgccgccg acatcggcac cggcgcccgc accgcgctca ccctggtggc cgccgacgcg
     4201 ctggaggtgg caccggagcg ggtccgggtc cgcatcggtg acagcgactt cggaccggcc
     4261 atgatcgccg gcggctcgat gggcacccgc tcctgggcct gggcggtcac ggccgccgcg
     4321 accgaactgc gggaacggct cgtcctgagc gacggcatcc cgccggaggg catcatggtc
     4381 cgctcggaca ccacggccgc catcggcgcc ctcgcccaga aggaacgcca ctcctacggc
     4441 gcccagttcg cggaggtcgc cgtggacccc gccaccggcg aggtacgcgt ccgccgcatg
     4501 ctcggcatct tcgcggccgg ccgcatcgtc aaccccctca ccgcacgcag ccagttcatc
     4561 ggcggcatga cctggggcat ctccatggcc ctgcacgagg aggcggtacg cgaccaggcc
     4621 tccggcggcc actacggcgc cgacctcgcc ggctaccacg tcgccgccca cgccgacgtc
     4681 cccgccatcg aggcggactg ggtggacgac cccgaccccg acgaccccgt cggcatcaag
     4741 ggcatcggcg agatcggcat cgtcggcgcg gcggccgccg tcgccaacgc cgtctggcac
     4801 gccaccggcg tacgccaccg ccatctgccg atccggcccg accgcgtcct gatggcaggc
     4861 cgggatgctt gacctggcca ccgagctgag cgcgtgggcc gaggagggcc gggacttcgc
     4921 cgtcgccacc gtcgtggcgg tgagcggcag cgccccgcgc ggtcccggcg cggccctcgc
     4981 cgtcgacagc gagggcacgg ccatcggctc ggtctccggc gggtgcgtcg agggcgccgt
     5041 gtacgagctg tgccaacagg cgctggcgga cggcgagacc gtcctgcagc gcttcgggta
     5101 cagcgacgag gacgccttcg ccgtcggcct gacctgcggc ggggtgatcg acatcctggt
     5161 cacccccgtc accgcccggt cacccgcccg agccgtcctg agcgccgcgc tctcggccgc
     5221 ctgcaaggac gagccgacgg ccgtcgcccg cgtcgtccgg ggcccggccg aactcctcgg
     5281 acaggccctg ctcgtacggc ccgccgggtc gcgcgagcag ggcgacagcg gtgtgggtgt
     5341 cggctcgtac gaaggcggtc tcggcggtca ccccgagctg gaccggacgg ccgccgccga
     5401 ggcgcgggcc atgctggaca gtggccgcac cggcacgatc gagctctccg cgagcggagc
     5461 gagatggggg tccccccgga cggagtctgg gggaggatcg cactgctccg gcggcctcac
     5521 gctgctcgtc gagacgaggg tgccgccgcc ccgcatgatc gtgttcgggg cgatcgactt
     5581 cgcggcggcg ctggtgcgcg cgggcaagtt cctcggctac cacgtcaccg tgtgcgacgc
     5641 ccgcccggtc ttcgccacgc ggacccgctt ccccgaggcc gacgacatcg tggtggactg
     5701 gccgcaccgc tacctccggc gcaccgagac cgacagccgg acggtcctgt gcgtgctcac
     5761 ccacgacgcc aagttcgacg tacccctgct gaagacggcc ctgcggatgc cggtcgcctt
     5821 cgtgggagcg atgggctcgc gccgcaccca cgccgaccgc gaccggcgac tgcgcgaagt
     5881 cggcctgacc gatggggagt tggcccggct caggtccccg atcgggctcg acctcggcgc
     5941 tcgtacgccc gaggagaccg ccctgtccat cgcggcggag atcgtcgcga cccggcgcgg
     6001 cggcacgggc gtaccgctga ccgggtcggg gacgccgatc catcgggagg cgggggagcg
     6061 gggagcggtg gcggcggcct gagtacccgg ggcggggcga ctgagtacgt ggtcggatac
     6121 cccgcgcccc gggccgctgc tgaactgtcg tcatggacac gcacacctcg cgcccgcgcc
     6181 ccctccgcaa cgtcaccgcc acggccaccg ccaccggttc ggccctggcg gtggccttgc
     6241 tcccgctggt cgtcggggcg ttggtggcac ggtcggtcgg cggtgacccg atggcgtcgg
     6301 tcaacgccct gatcgcgggc ggcggcgaac gggcgaaact gtgccggagc cagttgcccg
     6361 tcctgcggcg catccgcagg acgggcagca ggacgggtcg gcacccggcc ctgcgacggc
     6421 tactggccgg ccgtgaggac gtacgtgttg aggttcccca cggtcgtgag cggtgacggc
     6481 gagcccaggt cgtagcggtc cacggcaagg tagttgggct tcttgcgggc ggctggtgtg
     6541 cagaaggtct gcgcgcggtt gagcagcttg gcgttgtccg tctcggccgt gccgctgacc
     6601 gtgtagtcgc ggaagtggtt catgacgaac agcgggtgga aggcgggcga gtccgtggtg
     6661 agcggtcggc tcgtgcccca gcggctgtag caggaccagt cggagtcacc gatcccaccg
     6721 cccatggacc agtagttctc cacggtccac tcgcgctggt acatcacacc gaacgtgtca
     6781 cgggtcgtgt atccgctgga gacgtcactc gcgcgcgtac ggtcactgaa gatcagcagc
     6841 tgcttgcccc gggcggcgag atccgccatc gtcggccagc cgctcgtcgc gacgccctcc
     6901 tggtcgggcc ggtacagcac gtccgagaga ccgctgacgg aggccagcga cgacttcagt
     6961 atgtcggagg ccgtgtagtc ctccaggaag acggtgacca cctcacccgg atgggcctcc
     7021 aggaagtcga ccatgcgctg gaggtccgtg gcgagcggaa ccggactgct gaccccgtca
     7081 caactgttgt ggcacagcac ggcctgcccc gacacggtgt aggcgtcgag catgaacccc
     7141 cgtacgccgt cggtgagttg ctgagcgacg ccccgcgact ggttggggaa gagactgacc
     7201 gggaacgagg cgaagttgcc gtccactccg ttcgcgtagg cgttgtgcga ggtgaggaac
     7261 gagacctggt cgagggtgcg cgtgtcggtg gacggcatgg ccgtcgtggc gtaggtgacc
     7321 ggcgtgaggt accagcgggc gtaggtgccg ctcgacccga tctggacgac cgaggagtcc
     7381 gaggaggcgc ccgtcagata ctgcgaggtc ccgggcacgc cgatggtgta cgtgctgttc
     7441 gcggcctcgg tgatcgtcca cgtggtgccg tccgcgccac aggtcgtggt caccgccgag
     7501 gtgccgccgc gcccgaggca gatccccgac tcgtcggcgt tccgcaactg atggccgccg
     7561 ctgacggcga ccggagtcca ctgctggtgg tcctcgttgc ccttggggtt gtgcgcggcg
     7621 accgtaccgc cgttgtccgc cgcgttgagc ccggtgacgg agttctgcag atagaccgcg
     7681 tacgtgggga ccgccgcgac ggcggggccc gagaacgcga cgggcacgcc cagggcgagc
     7741 gcggcgaccg tgcacagggc acgggcacgg gcacgggcac gggtacgggt acgggtgagg
     7801 ctcacggggt tccttccact ccggcgcacc ggcattgatg tcattgatgt cagaggcatg
     7861 acacaccgag cgtcgggtcg cgcaccagtc ccgccacatg aagacatgat gagcgcgaac
     7921 tcgcctttgt tcttggggat tctgtggaga agatccgttt aaactcggaa acccgttcga
     7981 agagagaccg cacgtgagtg aaccgacagc ccctgtctgc ccgcagtgcg gtacgccccg
     8041 ggcgacggac ggcactccgg cctgctcctg cggccgtctc gcctcggacg cccaccgcga
     8101 cacccgtacg gcgcaggcgg aggccgtgga ggacttcgac ccggtacgca tacggccgtt
     8161 tgtgaaggtc ggtgacgaca ccgagccggc cgactcctcg gccgactcct cggcggacgc
     8221 cgaaggcacg ccggagccgg ggccgttgaa agacggcgat gaacccccgc tccctggcgg
     8281 gtcgaccggc ggcacacctg ccctcctcga cctcgacgag cgacctcccg tcgacagcga
     8341 cccgggcggt cagcggcggc gacgccgagc ggtgtcggcc gcaggggtgg gagtcgccgc
     8401 ggtggccgtc ctggtgacgg gcggaatcat cggcggactg ttctcgtacg acggaccgtc
     8461 gcgggacggc tccggacccg aggacatacg ggcgaacctc ccggaggccg cgcccggcca
     8521 ggaggcgtcg tcgtcatcgg cgtccccgtc cggtacggcc tcctcggcgt cgccgtccgg
     8581 gaacccgtcc acctcaccgg ccgcgacccc gaccgagagc cgaaccaccc cgaccggctc
     8641 cgccaccccg accagaaccc cctccaacag cggctccacc gccacggcgg ctcccgcgcc
     8701 gaccccgtcc gacagccagg accccgtcct cggcaccggc gacagcggac ccgaggtcac
     8761 cgaactccag ctccgcctgc gccagatcgg cttctacaac ggcgtcatcg acggcgacta
     8821 cgaccccgag gtcgagagcg ccgtccgcgg ctaccagctg acccgtgtcg tcgtggagga
     8881 cgagtcgggc gtctacggcc cggcgacccg cacctcactc gaatccgaga ccacggaacc
     8941 gtgacccgcc ctggctgacg ccggccgcgc tcgcggacgc gagcgaccgc gcgaccgggg
     9001 ggcggtcggc ggaacggacc cccgatccgc cggccgtccg cgccgggcgg tcagacccgg
     9061 tcggcgacga tcagcaggta ctggaaactg ccgttctcgt aggcggtgat gaaggtgtcc
     9121 tcgatgcccg tgaccaggtg gtcggcctgc ttgcggagct cccagtaggg cagggcggcg
     9181 gcggtcagat ccaccacgtg gacggggacg aggcggttgc gggccatcgc gcggaagtac
     9241 tcggagcgcg ggtggatgtc gcagatgtag tgggcgttga tgagggacac ctcgcgggag
     9301 gcccggccgt aggtgtcgtt gtagcagccg gtgatggtga catagcggcc gccgcggcgc
     9361 agcagccggg cgtgctcggc gaagagcagg tccagctcga cgtacatggt ggactcgttg
     9421 ttccaggacg ccgcgtactc cccggacggc agacccgtgt cgagcatgtc gcggtggtgg
     9481 tagcggaccc ggtcgtcgat gtcccgcttg cgggcctgct cattggcgaa ctcggcctgc
     9541 ttgcgggaga tggtgacacc gtcggcctgg cagccgtacc gcagatgggc caccacgctg
     9601 ccgccgccgc gcccgcagcc ggcgtcgaag acgcggtcgg tgggggagag ggggcccaga
     9661 tggtgggcga gcaggtcggc ctgggcctgt tccaggcggt gcagttcggc ggtgacccgg
     9721 tcgcggcggc gcgccggatc ggggtcgtcg tccaggacgg accagtccgc gtcgccgatg
     9781 ccgtagtggt ggtggtagag gtcgtcgatc ttgccgagtt cgaggttgac cgggttctcc
     9841 tcggcgttcc agtagtccgc gacacggttc tggtacgtgg accgggccgg ggaggacgtc
     9901 gggggctggg ccggcagggg cgtggcggtc gtggtgacgg cgtcgatgat ggtcaacggt
     9961 ggctcctccg gtgctgtggg gcgtcggcca tgcccgggcg ttaccagtag tcgggcaggc
    10021 tgtagcggtc ggtgttggtg gcgtgccact cgtggttgcc ggccacccag gcggcgagag
    10081 cggtggcgta gcgctcgatc aggggcgagg tggcggacag ggccgcggac tcctcctcga
    10141 acgcctccat gatccggttg tggatctcga cggcctccag atacgccgcc ttcagcccgc
    10201 accgctcgtt ggcggcgatg accatgggca gattgagatg gtccgggtcg ttcgacatct
    10261 ccttggtgaa ggagtacagg tcgttgacga tcgtggacgc gttcccggcc agcgcggtga
    10321 tccgctggac ctcgggccgg gcgtagacgg cctccggcag ttcccagccg tccaccgcgt
    10381 cgacgatcgc cagacagggg cggaagttgt tgaactgccg catcaccagg tactcccaga
    10441 tccgcggcat gtggtcggtc tcggcccagg cggcctcgcc gagatagccc agatgcagcc
    10501 gggcgagatc gtggacgagc cggtcggtct ggctgggggt ggcgagggcg gcgtagtccc
    10561 gcagcgcgaa gtggtacgaa cgcagcggac cgtcgccccg tacgccgtgc cgccaccgat
    10621 tctccacctc gggtgtgctg tggagggggt cgagcgccga ctgggccatg agcagccgac
    10681 cgccgaggcc gcgcggcgag ccgcccttgc cctcgtcgac ctcgcagtac aggttgtcga
    10741 cgaggtgctc ggcgagcagc aacttcccgg cggcggtgag gtgttcgggg ccggccgcgc
    10801 cagggtgcgc gagcacgatc gcccggccga gaccgaaccg cgcgaactgc ccccgccact
    10861 cccgggggaa cagatccatg cgctccgccc aggcctccag cctgcggtcg acctccgcgg
    10921 ccttcgcggg gtcggcgggc acggcgggcc ggtacctcag cccggggatc gcaccgccgc
    10981 cccgggcccg ccgggaccgg gcaggactcg gcggccccgg cagccgcctc cgggccggcg
    11041 cgcagaccga cggcagaccg ggcgacggga gatcggctga cggcagaccg gccgatgtca
    11101 cagccgggga cggcggaccg gctgacgcca taccgaccga cggcagaccg ggcgacggga
    11161 gatcggctga cggcggaccg gccgatggcg gaccggccga tggcggaccg gccgatggca
    11221 gaccggccga cgacacggca ccggacactg acggttcgtt cattccggca tccacccgac
    11281 ctgcacgttc tccaggatcc cggccgcgtc gggcaccagc acggccaacg agtagtaggc
    11341 ggtgaccaga taactcatga tcgcggtggt gtcgacgccc atgaaccgca cgttcagcga
    11401 cggctcgtac tcctcgggga tacccgtctg gtgcaggccg acgaccccct ggtccttctc
    11461 gccggtgcgc agcgcgatga tgctggtggt gtgctgcggc gtgatcggga tcttgctgca
    11521 cgggaagagc ggcaccccgc gccacgccgg cacctcgtgc ccgtcgacgt tcaccgtgcc
    11581 cggcaccaga ccgcgccggt tgcactgtcg gaagaaggcc gcgatcgcct tcggatgggc
    11641 caggtacagc cgggtcttgc ggcgcatgga cagcagctcg tccatgtcgt ccggggtcgg
    11701 cggcccggag aaggtgctga tccgctggcc gtagtcgatg ttgtgcagca gcccgaactc
    11761 gcggttgttg accagctccc actcctggcg ttcgcggatc tcctcgatgg tcaggcggag
    11821 ttgctgctcc gtctggtcca tcgggtggtt gtagagatcg gcgacccggg tatggacgcg
    11881 caacaccgtc tgggtgaggg agagttcgta ctcgcggggc gcgaggtcgt agtcgacgaa
    11941 gccgcccggg agcgccaact cgcccacgtg tcccgcctcc aggggcacat cggcctcgcc
    12001 cttgcggttc atgggcttgc gctgccgatc ggcgaaggcg tcgaactggg ccgcgaggga
    12061 cggcgtgcgc tccacgaacg ccatgagcgc gtcccagttg agggccagta ccacccccgc
    12121 cgtctcggcc cgcaccgagc tgagccagag cgggtcggcg tggccgatgg cctcgtcgcc
    12181 cagcccgtcg ccgtcggtga ggaggccgag gacctcctcc tcgccgtact tgccgatggt
    12241 gtaccgcgtg aaccggccgt gcaccacgag atacgcctcg gtcaccggct gcccggcgtc
    12301 caccagcacc tggccggcgc gcacttcacg cacccggaac cgggaggaga tctccctcag
    12361 ggcagggatg tcggagtagc cgcgcagcgc ggggagttcg gtcagtgtct ccgggatgac
    12421 cttgacgtcg tcggcgccgt tctggtcgaa ctgcacccgg ccccggccga tgcgcagctg
    12481 gaggcggcgg ttgacccggt aggtgccgcc cttgacgtcc acccacggca gcgtcttgag
    12541 cagccatcgc gaggtgatgg cctgcatctg cggttcggac ttggtggtcg tcgcgagctg
    12601 ccgcgcggcc ctggtgctga gactggtgaa ctgctgtgcg tcggcgggct ccggtgcact
    12661 ttcggaggag cttacggggg cggtcacatt ccctcccgat aggtgagcgg atgtgcgggg
    12721 acgtacgggg acacgcctgg acaccggcga aacgcggtgc tgtcgggaca cggaactcgg
    12781 gtggcgcgca tacgacttgg ccgtgggcgg attccgaggc gacggtcgcc ggagaggcga
    12841 ctgtgaggcg acatgtgcgg atgggcggaa cgtgtcgcgg ataagccaaa caggcgggac
    12901 ggccggtcgg gcaccgcgtg aagggggcga cttcgcgtcc tggggatgcg gaaaccaccg
    12961 actgaggcag agcaccgacc gctccgtgct cccgcgcccc tcgctcgcct cccgcgaccg
    13021 gcgcggaggg cgcacgacgc cgcccatgcg aaaggggccg cccatgcgaa aagggccgcc
    13081 cggaggcggc ccctttcggt cagcggtggt tcaccagcgg ggcagtcgca gctcgtaccc
    13141 cggctggatc cggcgcatgt accccgtgtc gtcccgggaa cgcatgcccg agtcgacata
    13201 cagccggtgc agccggccga gggcgtcgtg gtccagctcc acacccagcc cgggccccgt
    13261 gggcaccgcg acctccccgt cccggaactc cagtacgccg gggacgatca cgtcgtccgc
    13321 cgagttccac gggtagtgcg tgtcgcacga gtggtcgagg tgggggatgg ccgccgcgac
    13381 atgggtcatc gcggccaggc tgatgcccag gtgcgagttg gagtgcatgg acagcgcgat
    13441 cccgaacgcc tcgcagacgg cggccagttc acgggtgcgg cgcagtccgc cccagtagtg
    13501 gtggtcggtg agcagcacct ggatcgcgtc ccgctcgatc gccggcctca gatgctccca
    13561 ggcgaccacg cacatattgg tcgccagcgg catcggcgca tccttcgcca cctccgccat
    13621 accggggatg gtggcggtcg ggtcctccaa gtactccagt acgccgtcca gttcacgggc
    13681 gacgtacttc gaggtctcca ccgtccaggc cgtgttggga tcgaggcgca gcggctgccc
    13741 ggggaaggcc tcggcgaggg ccttgatcgc cgcgatctcc tcgtccggtg ggaagacacc
    13801 gcccttgagc ttgaacgacc ggaacccgta ccgctgtcgc atcagccgtg cctgctcgac
    13861 gacaccggcc gggtccagcg cctcgcccca gtcgtcgccg accgccgggc ggccgtcgag
    13921 cgccgggtgt tcggcccact tgtagaagag gtacgcggcg aagggcacgg agtcgcggac
    13981 ccggccgccg agcagatcgc tgaccgggcg gccgagcagc ttgccctgcg cgtcgaggca
    14041 ggccacctcg accaccgagg tggtccagcc gcgttcgtgg gagctgggca cggtcggcag
    14101 cagtacggcg tcgatcgcgg ccgagacggc ggtggtgtcg aagacgtcca ggccgaccac
    14161 cgccttcgcc gccgcttcaa gtcgctccag ccgcacggtg ccgcccgtag actcgccgag
    14221 ccccaccgtg ccgtcctcga ggacgagttg gaggatggtc cgcagcgcga gcggttcgtg
    14281 gacgccgctc gagttgagca gcggcgggtc gcggaaggcg atcggggtga cgatcagctc
    14341 ccggatccgg gtccccggcg tgccggtcat acgctcatcc tctcccggcc gtgaaggcca
    14401 aggccatgac gatcagggtc ctggcggttc ggcatcacgc gcccaccacc cccaggccgt
    14461 ggtcgatcag cttcgccagc cgggagacat gctccggtgc cgggtcgatc aggggagccc
    14521 gtacaccgcc gacgtccagg ccgcgcaggg tcacccccgc cttgatcagc gccacggcgt
    14581 acccgggcac ctcgtcccgc agttcgacga gcgggccgta gaactcgtcg aggagcgtgg
    14641 agaccagtgc ctcgtcgccg tcggcgagcg cccggtggaa ggcgagggcg atctccgggg
    14701 cgaaggcgaa cacggcggag gagtacaggc cgacgccgat gccccggtag gcgggcgcgg
    14761 tcatctcggc cgtgggcagc ccgttgaaga actggaagcc ctccgtgccc ggcacggccc
    14821 gtaccgcgcg gacgatgcgg tgcatccgct cgatgtcgcc gatgccgtcc ttgaggccga
    14881 cgacccctgg cagggtggcg atctcggcag cggtgtccgc ggtgagccgg gcggtgccgc
    14941 gctggtagaa gatgacgggc aggccggtgg ccgccgtgac ctcctcgacg taccggacga
    15001 gtccccgctg cggtgcgctc accagatacg gcggcagcag caggatgccg tcggcgccgg
    15061 cgcgttcgac ccgggcggcc tggtcgcggg cgaccggggg cgggccaccg gccgcggcca
    15121 ggacgggcac ccgcccggcc gtcaccgtga ccgcgacccg cgtggcccgc tcgatctcct
    15181 cgggcgtcag cgcgtggaac tccccggtgc cgcaggcgac gaacacgccc ccggcaccgg
    15241 ccgcgacccc ggcctcgatg tgctgtgcga gccgttcctc gtccagcgaa ccgtccgatg
    15301 cgaacggcgt gaccggaaag aacagcactc cttggaactt catgtctccc tcaaacgtgg
    15361 ggggttggca gatcagccct tggtggcccc ggcggcgatg ccggtgacca gcgagcgctg
    15421 gaggagcaga tagacgacaa ggctgggcag gagcgcgatg accgcgccgg cgaggacgac
    15481 gcccgagccg acctcgggat cggtgcgcag gatggagagg gccacggtga ccgtgtagtc
    15541 ggtcgggtcc ttggcggcga tcaacggcag cagatactga tcccagatca tgatgaagcc
    15601 gaggaccccg gccaccccga gcgcgggcct gcacagcggc agcacgacct gccacagcat
    15661 ccgcagttcg cccacgccgt cgaggcgggc ggcctcctcg atctccccgg gtatgtcctt
    15721 catgaactcg gtcagcagca tcaccgagaa gccccaggcc ccgagcggca ggatgacacc
    15781 ccagacggtg cccttcaggt cgatgccgac caccggcaca tggccgagga ccagggacag
    15841 cgggatggcg atgacctcct ccgggagcat catcgtcagc atgaacagcg tcatgacgat
    15901 cgcctgaccg cggaaccggt gacgggccag cgcgtacgcg gcgagcacgc acaccacgag
    15961 ctggagaagc agtccgccgc ccgcgatgac gagcgagttg gtgaagtagt cccagatgcc
    16021 gcgctccccg gccacccgga agttcagcag tgtgctgtcg tgcgggagga aggacagcga
    16081 cgagccgctg gggtgggtgc tgagggcacc ggagacgatc gtcaggaagg gcgccgcgaa
    16141 gatgccgagc gctgtcgcgc acagcaggat ccgcagggcc caggagacgc cgggccggtc
    16201 gttccagccg agcgcggtgt cgaagcgggc gggggtcgtc cgggcccgct tgccggctct
    16261 cccggatgac gcgacggcct cgtcggacga cggcgtccgg acggggtcga gggcgggtgc
    16321 gctcatcgca cgtctcccct cttgcggaag tggttgacgg tgacggtgag cagcagcgtc
    16381 accgcgagca ggacgacgga ggccgccgac gcgccgccga tgtcgttgcg ggtgaagccg
    16441 agggtgtagg cgcgggtcat ccacacctcg gtggacccgg cggggccgcc gcccgtgagg
    16501 acgtacacct cggtgaagac acgcagacca cggatcgcgg ccagtgtgag gacgatgccg
    16561 atggccgggc ggatcgccgg cagggtgacg tggcgaagcc gctgccacag ggacaccccg
    16621 tccatcgcgg cggcctcgta caacgtgcgg tccacgcccg cgagtccggc gaggatgatc
    16681 accatgttgt acggggcgac catccagatg cccatgacca tcgtcgccca gagcgcggtg
    16741 tccgggttgt cgaggaacgg agtcgggccg agccccagga agcccagggc gctgttcacg
    16801 aggccgtcgg aggtcgggta gtacatcagc cgccacagct caccgacgac ggcggtcgcg
    16861 gtgacgaccg gcaggaagac ggccgtgcgc atgatcttca gcgagcgggc ctggccctcg
    16921 agcagcagcg ccaggaagaa gccgacgacg atcgcgccga gcgactgccc gatgccgagg
    16981 aggagggtgt ggccgaccgc gtcctggaag cggtggtcgg tcaggacccg cgtgtagttg
    17041 tcgaggccga cccactggtc gccgaggaac ggccgtacgt cgaagaagct gagccagatg
    17101 cccttgccca tcgggaggaa cttgaagacg agggcgagca gcaggccggg ggccaggaac
    17161 agccagggga ggacggcctt cttgccgaag acccgcttgg tgagcgctcc gcgccgccgg
    17221 ggcgcgatgg tggtcgcggt catttcaaca ggtcctggtc cttgaggtca ccggcgaggg
    17281 tgtcgttgag ttccttgagg cttgagccga cgtcgctgcc gcagtaggtg aagaccgcgt
    17341 tgagggcgtc ggcggtgtcc tgcttgatcg gcgcgaagtc gggtgcgttc gggaactgct
    17401 cggaggcgtc ctcgtaggcc ttctgtacga cgctccagcg cgggtcgtcc cgcacctggg
    17461 ccgcgtcgag cgtggagttg acggggatgc ggaccacggg ctggttgtcg ccggtcatgg
    17521 cgagcttctg gccctcgggg gagatcagga aggcggcgag ggcctgctcc tgccgcgtct
    17581 tgccggtcct cgcgccgaag tagatgttct ccccgtcggc cagcacggtg gacccggccg
    17641 ggcccgccgg gaacgggacg acgtcgaacg tgtccttgcc gggcgtcgcg tcgtaggtgg
    17701 cgatgttgta cgggccggtg aggtacatcc cggcgtcgcc gtcctggaag ttggtggccg
    17761 tgccggtgac ggcggtgatg gcgccgggct ggatgacacc gttgtcaccg cagaagaggt
    17821 tgtccttcat ccaggtgacg gtgcgtacgg cggcggccga gtccatggcg gggcggtagc
    17881 ccttgccgtc cggctcgatg atcttcgcgc cgccggacca gaggaagctg gcgccccacc
    17941 aggcggcgta gccgttctgg gcgctgcccg ggacgaccat gccgtaggtg tccttcttgc
    18001 cgtcgccgtc cgggtcgcgg tcggcgaagg ccttcgccac gccgatcatc tccgcccagg
    18061 tcgtcggcgc ctggaggccg agtttccgca gccagtcctt gcggatcatc agggtctggg
    18121 cctggcggga gtacgggatg ccgtagtgct cgccgtcgat gcccacggtg gaggaccagg
    18181 tcttgtcggt gatctggtcg tggccctcga tcgcggccgg atcgatggtc tcgagcaggc
    18241 cctggctctg gtaactgccc atcagcgccg tgtcgttgat catcacgtcc gggaggtccc
    18301 tggtggacgc ccggctctgg agctgctggt cgaagttgat gaccggctgg taatcgatct
    18361 tgatgccggt cttctcggtg aaggcggcga acacccgctc gtacgtggcg gccgggtccg
    18421 gattgctccg ggtccagacc tccagcgtgt tcgggtcatc gcccccggcg ctgtcggacc
    18481 ccgatccgca gcccgcggcc ccgaacgcga gccccgcgac ggtgatcatg gcggccaggc
    18541 ggtgacttcg tcggcgaacg cccatgggca cactccgttg ttcttccggg ccgtccgccc
    18601 gggtgttcat attcgtgaac tcgcttcacg aatctaaatg atcggccaag ctacggagcg
    18661 tttcgttcgc acgtcaagac atgggtagga gatttcaccg gcgccacaca tgggcatacg
    18721 ggatcctgtc gggcgcctga gggcagggat ctggaggtgg tacgccgtga ccgatcgcac
    18781 ggcacccggt gccctggcgg cccgactcac cggccgcccg gcgaccggtg aacgccggct
    18841 gtccgggacg ctcgccgaag tcaccctcga cgacgggcgg gtggtgctcg tcaagctggg
    18901 cgacggcccc ggcgcggccc aggccgaggc ggcggggctg cgctggctgg ccgaggcggg
    18961 cacggtccgc gtcccgacgc tgtacggcca cgacaagggc cgcctggtga tcgaccgggt
    19021 ggcgcagggg gcaccgagtg ccgcggcggc gacccgcttc ggcgcggccc tcgccgtcct
    19081 gcacgccacc ggcgcgccct ccttcggcgc cccgccgccc ggcggcccga gggaggcgta
    19141 catcgggcgc gcacccatgc ggaacctccc cggcaccgac tggccggcct ggtatgccga
    19201 gcaccgcgtg ctgccgtatc tgcgccgcgc ggtcgacgac ggcacgatcc gcccggccga
    19261 ggcgcccctg atcgaggacg tctgcgaccg cctgcccgac ctcgcgggcc ccgccgagcc
    19321 gcccgcccgg ctccacggcg acctctggaa cggcaacgtc ctgtggggtg ccgacggcca
    19381 cacctggctc atcgacccgg cggcccacgg cggccaccgc gagaccgacc tggcgatgct
    19441 cgccctcttc ggctgccccc acctgggcca catcctcgac ggctaccagc gggcggcgcc
    19501 cctcgccgac ggctgggcgg accggatcgg actgcaccag ctcttcccgc tgctggtgca
    19561 cgccgtgctc ttcggccgtg gctacgcgga acaggcgctc gcggtggcgc gggcgacgct
    19621 cacgtggtga cccggcccgc atgcgggaag tggtgacctg ctcggccgcc gccgtccgcg
    19681 cgcacgcgaa accgggaggc gccgtatcgg cgccccccgg ttcgaggtca agggcgagga
    19741 aagcgaaaga gctgaggctc tatgaatgag atgagaagga agccccttca tggcctcgcc
    19801 acgggcaacg ttagcagtca ggcagggatc aagtcgcgca gattttcgag ggtggtgacc
    19861 tgggagtccg ggtgcagccc ctccgggcgt tcgagaccga tgtaggtgac gggcccgtcc
    19921 gggacggact tcccgtccca cggcgtcatg gctgtggcgc cgtcggcggt catgaggtcg
    19981 acaaggtggc ggaccgtcag ctggtcacgc tcgacgatgg cgcgcagcag cgccgcgacc
    20041 gtcacccggt tgccctccac ccggttctcc gacggactgc ccgtgagata caggtgcagc
    20101 cacttcgccc gccaccggcc gtcctcgccc cgctggaacg ccagcggcag cgcgacccgg
    20161 cccggccctc gcagctccga cttcatacgg acggtgcgcg cctcgaacgg ccgcccatgc
    20221 tgctcgccct cacgcagcat gaagccgaag aacgactcct cgacacgctc gaagctctcc
    20281 ccggagaaga tgttgacctc cgggacgatg aacgtgcccc ggacggcgtc caggcgcagg
    20341 ttgatgaact ccgaggcgcc gtgcggcgcc tcggtgatgt caccggaatg ctcgccgccg
    20401 atgtcggtga gctcggtgta ggagagccag gagacggttt cgtagttctc gtcgagcatc
    20461 agcgccgaca ggtcgtagtc ggtgtcgtgg gccgactgct tccagtggac gaagaagcgc
    20521 agcagttgcc cgtcgaccgg tgacagggag ccgcgcggca gtacgccgag accggccgcc
    20581 gtcgccttcc cgctcagcgg cagcgcgacg tccaggacgc cggggtcgac caacaggtgg
    20641 tccggcgtcg ggagccggtg gcgtatttcg gcgtccaggg cggcgatcag gcgctcgcgc
    20701 tccggcaccg gcaccggcgg gcgctggtcg tcggtgaccc aggcgccgcc gaggcggttg
    20761 acgaagaccc ggtgctcccc ggcgtcccgg gagcggttgt ggaggtgttc gcgcaccgac
    20821 agcacgagcc ggccggagac ctgcggggcc acctcctcgg cggccaccac gacggcgtcc
    20881 cgctcctcct gggtgcgcgc cgtccgcagc agccggtcca gcgcgcggaa cagcttgccg
    20941 ggagcggact tcagcagctt cacggcaccg aggacgtcga actcgtcgag cagcttctcg
    21001 acccggctgt cgaaggaccg cgcctccttc tcgccccgcg cgacggcgaa cacatcggcg
    21061 gcgtgcggcc agcgcgggta ctcgtgcggg tggagacgct caccgagccg cttgaacggc
    21121 tcgcggtgcg c
//
