LOCUS       NZ_CP102512            21029 bp    DNA     linear   CON 11-FEB-2024
DEFINITION  Streptomyces sp. CA-210063 chromosome, complete genome.
ACCESSION   NZ_CP102512
VERSION     NZ_CP102512.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CA-210063
  ORGANISM  Streptomyces sp. CA-210063
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10859970)
  AUTHORS   Nielsen,J.B., Gren,T., Mohite,O.S., Jorgensen,T.S., Klitgaard,A.K.,
            Mourched,A.S., Blin,K., Oves-Costales,D., Genilloud,O., Larsen,T.O.,
            Tanner,D., Weber,T., Gotfredsen,C.H. and Charusanti,P.
  TITLE     Identification of the Biosynthetic Gene Cluster for Pyracrimycin A,
            an Antibiotic Produced by Streptomyces sp
  JOURNAL   ACS Chem Biol 17 (9), 2411-2417 (2022)
   PUBMED   36040247
REFERENCE   2  (bases 1 to 10859970)
  AUTHORS   Joergensen,T.S., Gren,T., Blin,K. and Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2022) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 05-AUG-2022
            Assembly Method :: Flye v. 2.9-b1768; Polypolish v. 0.5.0; POLCA
            polisher from MaSuRCA v. 4.0.5
            Assembly Name                     :: M642_aaa1.6.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 55.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 11:12:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,501
            CDSs (total)                      :: 9,410
            Genes (coding)                    :: 9,051
            CDSs (with protein)               :: 9,051
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 359
            CDSs (without protein)            :: 359
            Pseudo Genes (ambiguous residues) :: 0 of 359
            Pseudo Genes (frameshifted)       :: 141 of 359
            Pseudo Genes (incomplete)         :: 302 of 359
            Pseudo Genes (internal stop)      :: 23 of 359
            Pseudo Genes (multiple problems)  :: 101 of 359
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:19:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3344935
            Orig. end                         :: 3365964
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102512.1.
            Bacteria and source DNA available from Tilmann Weber, Dr.
            Professor, Novo Nordisk Foundation Center for Biosustainability,
            Kemitorvet, 220, 327D 2800 Kgs. Lyngby, Denmark.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21029
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="14"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21029
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21029
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11029](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11029)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    1093..1104
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.42"
                     /tool="antismash"
     gene            1181..2200
                     /locus_tag="JIX56_RS14255"
                     /old_locus_tag="JIX56_14255"
     CDS             1181..2200
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480384.1"
                     /locus_tag="JIX56_RS14255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14255"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_257540743.1"
                     /transl_table=11
                     /translation="MTARITDVARAAGVSASTVSRALRGRPGVSDEVRTQIAAVAAQLG
                     YTASRSASSLASGRTYTIGVVAPYIGRWFFGTVLDAAEQVFSAAGYDVLLYNLGSAEAR
                     KRFFTKLPVRKRVDAVLSLLIPDEDESAALRSLGVPLASTVGGPRPGFTVVGIDDRAGA
                     ESAVRHLVNLGHRRIGMISGASGPLHWTTPVDRRAAYLHVLAEAGIEHDPALVADGDYT
                     VDGGERAMTELLAASRPPTAVFAQSDEMAMGALRALRRHRLRVPDDVSVVGFDDHELAD
                     VVGLTTVAQPVAGQGAEAARLLLSRLDEPDVEQPGHVQMPIRLVLRETTAPPRPRGPQ"
     gene            2294..3745
                     /locus_tag="JIX56_RS14260"
                     /old_locus_tag="JIX56_14260"
     CDS             2294..3745
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480385.1"
                     /locus_tag="JIX56_RS14260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14260"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_257540745.1"
                     /transl_table=11
                     /translation="MSPTISSTGSSTGSSTGNSTGNSTGSSTGNSTGNSVDSSARGRFR
                     RTARTSLALVLPLAALAACGGGGNGDTSAEAGSGEGTISVWAHQGQKSESEALQSAVES
                     FNSSQDKVKVELKLIPETDYTKTITATDADKLPDVLEFDGPTMANFVYNKKLAAIDDYV
                     SAKTLDNATDASKAQGEIDGKHYGLGMFDSGLGMYGSKKLLDAAGVTYPKGVDDAWTAD
                     EFDAALKALKAKDSDGKVIDLQEGTGYANEWGTYGFAPIVWSAGGSLLKDGKAEGALDT
                     PAVVSAMKTFQSWKTYTDANTDGNAFAKGRVALSWVGHWMYPAYSEALGDDLVVLPLPD
                     FGDGPKTGQGSWAWGVGAASKNAKAAGTFLDFLLNDASVGAMTKANGAPPATKSALAAS
                     ELYKQGGPLQLFADQLAKPCGDSDISESCVAVTRPVTAGYPVVTAKFSEAVNSIYGGTD
                     PKDALSEAARAIDRDFSDNAGYEIP"
     misc_feature    complement(2336..2351)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.15"
                     /tool="antismash"
     gene            3917..4903
                     /locus_tag="JIX56_RS14265"
                     /old_locus_tag="JIX56_14265"
     CDS             3917..4903
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009719635.1"
                     /locus_tag="JIX56_RS14265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14265"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_257540747.1"
                     /transl_table=11
                     /translation="MKTVEPAPAAAPGRKQASPVGAPARRPSRRNREWLHGLLMSAPAV
                     AGLIAFVGIPFCYAVVLSFYNVRLGSPLEPTFFGVEQYRRLFTDPDLSGPFLRALLNNL
                     TFAVVVVPLQTGLALGLAILLNRKLKAIGLFRSLFFMPVVFPMALVAVIWRLILARSDQ
                     GMLNSALDAVSFGNWGAFDWLGDGLTAMASIIVLSVWQGVGFQMVILLAGLQQIPGELY
                     EAAELDRASPWQQFRHVTLPGIRGTLVFVALLTSVLSFRVFDQVYVLVKGGGLDEDAAR
                     TVMYQAVTTAFDQNNIGQASAITVVFFLIVVVLTLIQRRLVRPDNED"
     gene            4911..5771
                     /locus_tag="JIX56_RS14270"
                     /old_locus_tag="JIX56_14270"
     CDS             4911..5771
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009306079.1"
                     /locus_tag="JIX56_RS14270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14270"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_257540749.1"
                     /transl_table=11
                     /translation="MSTSTSTGLSRGSLRRFLDYAVLSVLAFVFALPVLYLLLGSLKPS
                     DEVLDGLSGFLPTHLSFDNYSAVLDSLNSDSTGYFWQFMGVSLLLAFVVVTGGLFINSM
                     AAYGLSRLKWRGREAVFTLVLLLMLVPFESVAVPLFYMFNDQRNTLFIQALPFVANAFS
                     VYQFHTFFRSIPPSIEEAARLDGAGPWRTFFAIIVPMSKPAFASVAILTFLTQWGSFLW
                     PVLMVSDPSVRPLPLEMSVFQGQQPPDWGQILAFGVLLVLPVLIVFAFFQRWFVQGVAS
                     SAVKG"
     misc_feature    complement(5809..5828)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.44"
                     /tool="antismash"
     misc_feature    5968..5982
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            6016..6441
                     /locus_tag="JIX56_RS14275"
                     /old_locus_tag="JIX56_14275"
     CDS             6016..6441
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559754.1"
                     /locus_tag="JIX56_RS14275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14275"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_257540751.1"
                     /transl_table=11
                     /translation="MNRDDLVRLRRARDRMDREYAEPLDVTALARTALMSPGHFQRSFR
                     AAFGETPYGYLMTRRIERAKALLRRGDLTVTEVCLAVGCTSLGSFSSRFTELVGETPSA
                     YRARSHDESAVIPACVAKRLTRPARHRIRTAEPGEAS"
     gene            6475..6906
                     /locus_tag="JIX56_RS14280"
                     /old_locus_tag="JIX56_14280"
     CDS             6475..6906
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000781.1"
                     /locus_tag="JIX56_RS14280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14280"
                     /product="VOC family protein"
                     /protein_id="WP_257540753.1"
                     /transl_table=11
                     /translation="MTRLPAPDVKLAQCFLAVDDHDKALAFYRDVLGMEVRGDVGFEGM
                     RWVTVGSPLQPDVEIVLEPPAADPDISPADRETIATLLAKGVLRGVNFTTTDCDALYAR
                     VESSGADVLQEPTDQPYGVRDCAFRDPAGNMLRFMERRP"
     gene            7103..7837
                     /locus_tag="JIX56_RS14285"
                     /old_locus_tag="JIX56_14285"
     CDS             7103..7837
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058264.1"
                     /locus_tag="JIX56_RS14285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14285"
                     /product="VOC family protein"
                     /protein_id="WP_257550854.1"
                     /transl_table=11
                     /translation="MRWTYAFVDRPAAGFERACAFWTAVTAAKLSEPRGERGEFVTLLP
                     ETGDACVKAQGVASGDGGAHLDFAAEDVPALVDRAVRLGAEVVTPNDGWAVLRSPAGHL
                     FCVVPWHGESVRTPVVEGSRLDQVCLDVSPAEFDGEVAFWAALSGWDSRAGSLPEFHVL
                     RPPTGLPIRILLQRLDTPRPASAHLDLACADIDATRTRHEHLGATFVAGHPHWTVMRDP
                     AGGTYCLTGRDPETGGLPPRAE"
     gene            complement(7891..8229)
                     /locus_tag="JIX56_RS14290"
                     /old_locus_tag="JIX56_14290"
     CDS             complement(7891..8229)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480393.1"
                     /locus_tag="JIX56_RS14290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14290"
                     /product="hypothetical protein"
                     /protein_id="WP_257540755.1"
                     /transl_table=11
                     /translation="MGIDEQVCPVCGQPVATVVRRHKTLGAWVPVWSPGPCRNPKCEAY
                     VDEAVEAQTAAAEKPRAVARRTHGSHGAHGGHDAHGGHDVHVGEADKQVEVTAETAETA
                     EASTEKKA"
     gene            complement(8360..8944)
                     /locus_tag="JIX56_RS14295"
                     /old_locus_tag="JIX56_14295"
     CDS             complement(8360..8944)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973718.1"
                     /locus_tag="JIX56_RS14295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14295"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_257540757.1"
                     /transl_table=11
                     /translation="MRKLTYLIACSIDGFIGDADGDASFMYPFVVGDFAEYLKAEHPDT
                     NPTQVRRLIGTDGLANKDYDTIIQGRASYDVALKEGITSPFAHLREYVASRTLKESPDP
                     NVEIISDDLVGKVRELKAEDGGLGIYLCGGSAVAGALVDEIDELIIKTYPIVLGTGMPM
                     FGSGFAVSEFTLDEVRSFDNGVLVRTYSRKR"
     misc_feature    complement(9004..9020)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.9"
                     /tool="antismash"
     misc_feature    complement(9004..9020)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.71"
                     /tool="antismash"
     misc_feature    complement(9007..9020)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.68"
                     /tool="antismash"
     gene            9070..9660
                     /locus_tag="JIX56_RS14300"
                     /old_locus_tag="JIX56_14300"
     CDS             9070..9660
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480397.1"
                     /locus_tag="JIX56_RS14300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14300"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_257540759.1"
                     /transl_table=11
                     /translation="MVRNPERRAALLDAAVAVLAREGARGLTFRAVDAEAGVPVGTASN
                     YFADRDALLHQIDTRLQERLTPDPAVVEELLKAPKDRSLVMAFMRDLLARVTGDRTGYL
                     AHLELRLEATRRPALHASYTESVRGELDFGMSFHREAGLPGGDETVMVLYLAMQGLLLE
                     HLTLPDVLDNALPGVPAPEGLMERIVESIVPEH"
     gene            complement(10001..11029)
                     /locus_tag="JIX56_RS14305"
                     /old_locus_tag="JIX56_14305"
     CDS             complement(10001..11029)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190571.1"
                     /locus_tag="JIX56_RS14305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14305"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_306819849.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.8e-58, bitscore:
                     196.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAFDGQEAAEILEQARVSVDPELRRAVGSLPGSMRRVARYHFGW
                     EHADGTPAAGNAGKAIRPALVLAAVAALGGRESAAVRAAAAVELVHNFTLLHDDVMDRD
                     TTRRHRATAWTVFGIPDAILAGDALQALAQQLLAEDPHPASAAAAARLASCVVELCAGQ
                     HTDTEMEGRRPQDVTLDEVLAMAEAKTGALLGCACALGALYAGAGEEDVQALDAFGREA
                     GLAFQLIDDVIGIWGDPSRTGKPAGADLMVRKKSLPVVAALASGTPEAAELAELYGLPY
                     EEGDLERTALVVERAGGRDWAQIQAADRMARAMHELSRAVPDPESAGGLLALAEFVTRR
                     SS"
     gene            complement(11338..12744)
                     /locus_tag="JIX56_RS14310"
                     /old_locus_tag="JIX56_14310"
     CDS             complement(11338..12744)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="JIX56_RS14310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14310"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_257540762.1"
                     /transl_table=11
                     /translation="MSVGEEVRSQQDRPQQSLGTAAARNLATTTKSTPQMQEISSRWLL
                     RTLPWVNVQGGTYRVNRRLTYAVGDGRVTFVKTGDRVAVIPAELGELPALRTYEDIDVL
                     GELAQRCEQREFSPGDVLAEFGSHAEEVFLLAHGKVEKIGTGPYGDDAVLGVLADGAYF
                     GDQSLLDPDAIWEYTARAVTACTVLVLPRAAVEQISERAETLSEHLQEQRSIPSQRTNK
                     YGEKEIDLAAGHSGEPDIPHTFVDYEAAPREYELSVAQTVLRIHTRVADLYNQPMNQTE
                     QQVRLTVEALKERQEHELINNREFGLLHNCEYDQRLQPHDGVPSPDDLDELLSRRRGTK
                     LLLAHPRAISAFGRELNKRGLVPETIDIAGNRIPTWRGVPIYPCNKIPVTEARTTSIIA
                     MRTGEEDQGVIGLRAANIPDEIEPSLSVRFMGINEQAIIKYLVTAYYSAAVLVPDALGV
                     LENVEIGRWR"
     gene            13037..13627
                     /locus_tag="JIX56_RS14315"
                     /old_locus_tag="JIX56_14315"
     CDS             13037..13627
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142330.1"
                     /locus_tag="JIX56_RS14315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14315"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_257540764.1"
                     /transl_table=11
                     /translation="MAPPMSAGRFLTVLKNEGVRVVEVGDWEHHNRNHKGPWGPVHGVM
                     IHHTVTSGSERTVRICRDGYSGLPGPLCHGVITKDGRVHLVGYGRANHAGFGDDDVLRA
                     VIAEKALPLDNEANTDGNRHFYGFECENLGDGKDPWPKAQLDAIERVSAAICRHHGWNQ
                     RSVIGHLEWQPGKVDPRGFTMASMRERIRARLK"
     misc_feature    13665..13679
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.02"
                     /tool="antismash"
     gene            13685..14602
                     /locus_tag="JIX56_RS14320"
                     /old_locus_tag="JIX56_14320"
     CDS             13685..14602
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000787.1"
                     /locus_tag="JIX56_RS14320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14320"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_257540766.1"
                     /sec_met_domain="PALP (E-value: 8.1e-18, bitscore: 63.9,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGHPRAPDPDPATALRPRLPSPLQEVADDRFARHGVRLLLKRDD
                     LIHPQLIGNKWRKLVPSLRAAAGRPLLTFGGAYSNHLRATAAAGRLLGVPTIGVVRGQE
                     LADRPLNPSLARCTADGMRLHFVDRSTYRHKTDPATLAAVLRAAGAEDAYVVPEGGSNA
                     LAVRGCQDLGTELRGRADVVAIACGTGGTLAGLAAGLAPDQRALGIPVLKGGFLEEEIR
                     RLQDQAFGGPRGDWRLDERFHFGGYARTTPELDAFAADFETRHGLPVERLYVAKLLHGL
                     VTLTSEGVFPRGTTITAVITGRPF"
     gene            complement(14599..16194)
                     /locus_tag="JIX56_RS14325"
                     /old_locus_tag="JIX56_14325"
     CDS             complement(14599..16194)
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072182.1"
                     /locus_tag="JIX56_RS14325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14325"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_257540767.1"
                     /transl_table=11
                     /translation="MHFLPLLLLVAGSATVAGAARRTPVPAPLLLVAVGLVVSYLPGVP
                     HYELDPEIVLPLILPPLLYTAAGDSSYLDLRAQLRPVALLSVGYVLFATLSVGWAAYMI
                     VPGLPLTAALVLGAIVAPPDAVAATAVARRVGLPSRITTILQGESLVNDATAITAYRVA
                     LAAAVGEGASWTGGIVEFLVAAVGGVAVGLLLMMPIHWLRTHLKEALLQNTLSLLIPFV
                     AYGLAEWVHASGVLAVVVVGLYLGHRNWQVDFATRLQEEAVWKMVAFLLESAVFALIGL
                     QLQVVLEGLGEYEGVRAGWYAVAVFLVVVASRFIWVYPATFLPRMLSRRIREREGNPTW
                     KGPFVVAWAGMRGVVSLAIAFSIPLTVHGGEDFPERNLILFLTFTTVIGTLVIQGLTLP
                     PLIRVLKLPGRDQQAETLAEANAQAQASRAAEARLDELLANESNELPPPLVDRLRTVLE
                     RRRNAVWERLGAVNPVTGESVDDVYSRLSREMIGAEREMFVRLRDGRYIDDEMLRTLLR
                     RLDLEEAAVYREAS"
     gene            16255..16515
                     /locus_tag="JIX56_RS14330"
                     /old_locus_tag="JIX56_14330"
     CDS             16255..16515
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="JIX56_RS14330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14330"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_257540769.1"
                     /transl_table=11
                     /translation="MKQCTHADALPHPEPEPLSETCPECLAAGSHPVQLRMCLECGHVG
                     CCDSSPMRHATEHHKESGHPIMRTFEAGESWRWCFVDHVLV"
     misc_feature    complement(16716..16729)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            16867..17280
                     /locus_tag="JIX56_RS14335"
                     /old_locus_tag="JIX56_14335"
     CDS             16867..17280
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="JIX56_RS14335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14335"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_257540770.1"
                     /transl_table=11
                     /translation="MSQIAGEPGTQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCTFRLIDDSLEVTVSAPTTDGHAPARDTFAWTV
                     LSALAGKVSSAVADDKTVSISLYKQRGAGPGPA"
     gene            17277..18434
                     /locus_tag="JIX56_RS14340"
                     /old_locus_tag="JIX56_14340"
     CDS             17277..18434
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030133.1"
                     /locus_tag="JIX56_RS14340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14340"
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="WP_257540772.1"
                     /transl_table=11
                     /translation="MRNGDGPVRDEERGTRELPAEDDGGPSGPAHLADGVDGIPEQARP
                     HPEDDSSAAAGASRWAEPADGEEREALSDGQRDPESALRSTTSSRGRTGASPARAQSRA
                     GGTVTAGGTMSEHERHDEAGAQSVRSTQHDPQDRSGARALFVQLRALPDGSAEYAELRN
                     RLVRMHLPLVEHLARRFRNRGEPLDDLTQVATIGLIKSVDRFDPDRGVEFSTYATPTVV
                     GEIKRHFRDKGWAVRVPRRLQELRLALTTATAELSQQHGRSPTVHELAEKLAISEEEVL
                     EGLESANAYSTLSLDVPDTDDESPAVADTLGAEDEALEGVEYRESLKPLLEDLPPREKR
                     ILLLRFFGNMTQSQIAQEVGISQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(18543..18995)
                     /locus_tag="JIX56_RS14345"
                     /old_locus_tag="JIX56_14345"
     CDS             complement(18543..18995)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000792.1"
                     /locus_tag="JIX56_RS14345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14345"
                     /product="hypothetical protein"
                     /protein_id="WP_257540774.1"
                     /transl_table=11
                     /translation="MSPEQNPTPDTSDAEPRPGRLTAAAALAALEGVALLVGGGAMLVL
                     GFTGDSGDLSTGVTGGITLIALALLPLIAARGLLLRRGWSRGPAVITQIMALPVAYNLL
                     RADSLSIPAGIVLAAVAVAALVLLINPATTQALGIQGPGRAEETKR"
     gene            19169..20140
                     /locus_tag="JIX56_RS14350"
                     /old_locus_tag="JIX56_14350"
     CDS             19169..20140
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127486.1"
                     /locus_tag="JIX56_RS14350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14350"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_257540776.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LARRAAEGKDDIELVVALGGDGTVNEVVNGLLHHGPDPDRLPRLAVVPGGSTNVFARAL
                     GLPNDAVEATGVLLDALRESRERTVGLGMASGTPGTEDEAVPSRWFTFCAGLGFDAGVI
                     GRVEQQRERGRKSTHALYLRQVFRQFLEEPHRRLGTITLERAGEEPISDLVLSIVCNTS
                     PWTFLGNRPVYASPKASFDKGLDVLGLSRMSTPAVARYGTQLLTSSPERGPRGKHATTL
                     HDLTDFTLHSKAPLPLQMDGDHLGLRTSVTFTGVRRALRVIV"
     misc_feature    complement(20230..20239)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(20350..20365)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.73"
                     /tool="antismash"
     misc_feature    complement(20402..20417)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    20405..20416
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            20461..20718
                     /locus_tag="JIX56_RS14355"
                     /old_locus_tag="JIX56_14355"
     CDS             20461..20718
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="JIX56_RS14355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_14355"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_003992873.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVIEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA"
     misc_feature    20951..20965
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.43"
                     /tool="antismash"
ORIGIN
        1 cggggacctc caggtcgccg accgcgtgga gggtgggggc gatcgtctcc tcgcccagcc
       61 aggcctccag tcccggccac caggccaggt gtggggcgga atcctccggt acgacaaggg
      121 acttgggctg ggcgagcatg ccgcggcagc ggtcgcccgt gtcggtgagg ccgacacggc
      181 ggggggtggt gtggaggacg acccgggagc catcgggcgc ggggatcacg cggggggcgt
      241 acgcccccgt ggggccgagt tggccacggc gggtccaggg gccgcgcagg cgcggggccg
      301 tccacgcctc gaagccgcgc gtcgcgccga tggagccgag gaggagccag gtgccgtcgt
      361 cgaggcgttc caggacgggg cattccaact cgtccacgtc gccgggtgag atcagcggcg
      421 ggtggaccgt ccagtgctcc aggtcggggg aggtggcgag ggcgacgcag ccgctgactt
      481 cgacggggag ggaggcgtcg gcggcgcaga tcaccatcac ccagccgtcc gactcgtcgt
      541 caggtacgac gaacgggtcg cgccagccca tccgttcacc ggtgcggtac cagcgcgcgt
      601 ccgcctcgac gacgggtccg gtgccgtggc gccgccaccc cgtgccgtcg gtgcggtccg
      661 cgtacgccag gccgacggac tggagcggcc agccctccgg cgtcagtccg ctcacgcccg
      721 tgtagaacat cgccattccc gtgccgtggc ggaaggggtg catcgtccag accgcctgct
      781 ggtcgaagcg gccgggcagg ccgttgccga aggcggtgcc ctcgggccgc cagtggacca
      841 ggtcggcgga ggtggcccgg ccgtaggagg tctccatccg cagatggtcg aactcggcgg
      901 tccaggggcc ctggagatgc agcacggtgt aggtgccgtc gtcgtcgcgg agcagggcga
      961 agtcgttcac gcagaggccg ggcggggcgt atcgcatgcg cagcagtcct gtcggctcgc
     1021 agcgcccaaa cgcgtgcgct gaccatgaat ctggaaggtc tcacttgaga atcagcgcca
     1081 gtaaaactga acgcaaacgc ttgcgcaaca aggaggccgg gtttacggtc acgtcacccc
     1141 acagaccaca ccgacgtgaa accgatggga gaaatccgcc gtgacggctc gcatcaccga
     1201 tgtcgcccgc gccgccggtg tctcggcgtc caccgtgtcc cgcgccctgc gcggccggcc
     1261 gggcgtctcg gacgaggtgc gcacccagat cgcggccgtc gccgcccaac tcggttacac
     1321 ggcgtcccgc tcggcgtcca gcctcgccag tgggcgcacg tacacgatcg gggtcgtcgc
     1381 cccgtacatc ggccgctggt tcttcggcac cgtgctggac gccgccgagc aggtgttcag
     1441 cgccgccggg tacgacgtgc tgctctacaa cctgggctcg gccgaggcgc gcaagcgttt
     1501 cttcaccaag ctgccggtgc gcaagcgggt cgacgcggtg ctgtcgctgc tgatcccgga
     1561 cgaggacgag tccgccgccc tgcgctcgct cggggtgccg ctggcctcca cggtcggggg
     1621 ccctcggccc ggcttcaccg tggtcggcat cgacgaccgg gcgggcgcgg agagcgccgt
     1681 acggcatctg gtgaacctcg gccaccgccg gatcggcatg atctccgggg ccagcggtcc
     1741 gctgcactgg accacgcccg tcgaccgccg cgccgcctat ctgcacgtcc tcgccgaggc
     1801 cgggatcgag cacgacccgg cgctggtggc ggacggcgac tacaccgtcg acggcggcga
     1861 gcgggcgatg accgagttgc tggccgcgtc ccggccgccg accgccgtgt tcgcccagtc
     1921 cgacgagatg gcgatgggcg cgttgcgcgc gctcaggcgg caccgtctcc gggtgccgga
     1981 cgacgtgtcc gtggtgggct tcgacgacca cgagctcgcc gatgtggtcg ggctgaccac
     2041 cgtcgcccag ccggtcgcgg gtcagggcgc ggaggccgcc cggctgctgc tgagccgcct
     2101 ggacgagccg gacgtcgaac agccgggcca tgtgcagatg cccatccgac tcgtcctgcg
     2161 cgagacgacg gcgccgccgc gcccgcgcgg gccccagtaa gtcccctaag tccccgttct
     2221 ctcacttctc ttgagctcca ctcccccacg ccggaaagca ccccgcaccc tcgtccgcac
     2281 ggaggcacag accatgagcc cgaccatcag ctcgaccggc agctcgaccg gcagctcgac
     2341 cggcaattcg accggcaatt cgaccggcag ctcgaccggc aattcgaccg gcaattcggt
     2401 cgacagctcg gcccgcggaa ggttccgccg tacggcccgt acgagcctgg ccctggtcct
     2461 tcccctggcg gcactggccg cctgcggcgg gggcgggaac ggtgacacct ccgcggaggc
     2521 cggcagcggc gagggcacga tcagcgtctg ggcccaccag ggccagaaga gcgagtcgga
     2581 ggcgttgcag agcgcggtgg agtcgttcaa ctcctcgcag gacaaggtca aggtcgagct
     2641 gaagctgata ccggagaccg actacaccaa gacgatcacc gccacggacg ccgacaagct
     2701 gcctgacgta ctggagttcg acggcccgac catggcgaac ttcgtctaca acaagaagct
     2761 cgccgccatc gacgactacg tctccgccaa gaccctcgac aacgccaccg acgcgagcaa
     2821 ggcgcagggc gagatcgacg gcaagcacta cggcctgggc atgttcgact ccgggctcgg
     2881 catgtacggc agcaagaagc tgctggacgc ggccggggtg acgtacccga agggcgtgga
     2941 cgacgcctgg acggcggacg agttcgacgc cgcgctcaag gcgctgaagg cgaaggattc
     3001 cgacggcaag gtcatcgacc tccaggaagg caccggctac gccaacgagt ggggcaccta
     3061 cggcttcgcc cccatcgtct ggtcggccgg cggctccctg ctgaaggacg gcaaggcgga
     3121 aggcgccctc gacaccccgg ccgtggtgtc ggccatgaag accttccagt cctggaagac
     3181 gtacacggac gccaacaccg acggcaacgc cttcgccaag ggccgggtcg ccctgagctg
     3241 ggtcgggcac tggatgtacc ccgcctacag cgaggcgctc ggcgacgacc tggtcgtact
     3301 gccgctgccc gacttcggcg acgggccgaa gaccggccag ggttcgtggg cctggggtgt
     3361 gggcgcggcc agcaagaacg ccaaggcggc gggcaccttt ctggacttcc tcctgaacga
     3421 cgccagcgtc ggcgcgatga cgaaggccaa cggcgccccg cccgccacca agtccgcgct
     3481 cgccgcgagc gagctgtaca agcagggcgg cccgctccag ctcttcgccg accagctcgc
     3541 caagccctgc ggtgacagcg acatcagcga gtcgtgtgtc gctgtcaccc gcccggtgac
     3601 tgccggatac cccgtggtga ccgcgaagtt cagcgaggcc gtgaactcga tctacggcgg
     3661 caccgacccg aaggacgccc tgtccgaggc cgcccgcgcc atcgaccggg acttctcgga
     3721 caacgccggt tacgagatcc cgtaggaacg cgccccatcg ggcccatcga gcctgtcgga
     3781 tctgtcggac ctgtcgggtt cagtcggacc tatcggaccc atcggaccca tcggacccat
     3841 cgggttcagt cgaacccatc ggccggggcg ggcgcgcact ccgcggccgc ccgccccgcc
     3901 gggaagagga ccccccgtga aaaccgtgga acccgcgccc gcagcggccc ctggccggaa
     3961 gcaggcctca cccgtcggcg caccggcccg gcggccgtcc cgccggaacc gcgagtggct
     4021 gcacggactg ctgatgtccg cgcccgccgt cgccgggctc atcgccttcg tcggcatccc
     4081 cttctgctac gccgtggtgc tctccttcta caacgtgcgc ctcggctccc cgctggagcc
     4141 caccttcttc ggcgtggagc agtaccggcg gctgttcacc gaccccgacc tgtccggccc
     4201 gttcctgcgg gcgctgctga acaacctgac cttcgccgtg gtcgtcgtcc ccctccagac
     4261 gggcctcgcc ctcggcctgg cgatcctcct gaaccgaaaa ctgaaggcga tcggtctttt
     4321 ccggtcactc ttcttcatgc cggtcgtctt cccgatggcc ctggtcgccg tgatctggcg
     4381 gctgatcctc gcccgcagcg accagggcat gctcaactcg gcgctggacg cggtgagttt
     4441 cggcaactgg ggcgcgttcg actggctcgg cgacgggctg accgcgatgg cctcgatcat
     4501 cgtgctctcc gtctggcagg gcgtcggctt ccagatggtg atcctgctcg ccggactcca
     4561 gcagatcccg ggcgagctct acgaggccgc cgagctcgac cgggcgtccc cctggcagca
     4621 gttccggcat gtaacgctgc ccggcatccg cggcacgctc gtcttcgtcg cgctgctcac
     4681 ctcggtgctg tccttccggg tcttcgacca ggtctacgtc ctggtcaagg gcggcgggct
     4741 cgacgaggac gccgcccgca cggtgatgta ccaggccgtc accaccgcct tcgaccagaa
     4801 caacatcggc caggcgtccg cgatcaccgt cgtcttcttc ctgatcgtcg tcgtcctgac
     4861 cctgatccag cgccgcctcg tacggcccga caacgaggac tgactcagac atgagtacga
     4921 gcacgagcac cggtctctcc cgcgggtccc tgcgccgctt cctcgactac gccgtcctct
     4981 ccgtcctggc gttcgtcttc gcgctgcccg tcctctacct cctcctcggc agcctcaagc
     5041 cgtccgacga ggtcctggac ggcctgtccg gcttcctgcc gacccatctg tccttcgaca
     5101 actactccgc cgtcctggac agcctgaact ccgacagcac gggctacttc tggcagttca
     5161 tgggcgtctc gctgctgctg gcgttcgtgg tcgtgacggg cggcctcttc atcaactcga
     5221 tggcggcata cgggctttcc cgcctgaagt ggcggggccg ggaggccgtc ttcaccctcg
     5281 tcctgctgct gatgctggtg ccgttcgagt cggtggccgt gccgctgttc tacatgttca
     5341 acgaccagcg gaacacgctc ttcatacagg cgctcccctt cgtcgccaac gccttctcgg
     5401 tctaccagtt ccacacgttc ttccgttcga tcccgccgag catcgaggag gcggcccggc
     5461 tggacggagc gggcccctgg cgcacgttct tcgcgatcat cgtcccgatg tcgaagccgg
     5521 cgttcgcctc cgtggcgatc ctgaccttcc tcacccagtg gggttcgttc ctgtggccgg
     5581 tgctgatggt ctccgacccg tccgtacgtc cgctgccgct ggagatgagt gtcttccagg
     5641 gacagcagcc cccggactgg ggccagatcc tcgccttcgg cgtcctcctc gtcctgccgg
     5701 tcctgatcgt cttcgccttc ttccagcggt ggttcgtgca gggggtggcc agctcggcgg
     5761 tgaagggctg accgcgcacg ggggcggggg cggtagtgag gccggcgacg ggggcggatc
     5821 gtccgcgagg ggcacgagca gggcccgcat ccggggcccg gtggctcccg gtggctcccg
     5881 gtcgcgagag gtgccccggg gaacaggaag gtcggctcga cgctcgatgc tcatcgggcc
     5941 aggtcagcga gccgaccctc cctcggcgga ccccatcggc cacccattgt cagtggccgg
     6001 tgcgatgctg tgggcatgaa ccgggacgat ctggtgcggc tgcggcgggc gcgcgaccgc
     6061 atggaccgcg agtacgccga gccgctggac gtgaccgccc tcgcccggac cgcgctgatg
     6121 tcccccggcc acttccagcg cagcttccgc gcggccttcg gcgagacccc gtacggctat
     6181 ctcatgaccc gccgcataga gcgcgccaag gcgctgctgc gccgcggcga cctgacggtg
     6241 acggaggtgt gcctggccgt gggctgtacg tcactgggct ccttcagctc ccgcttcacg
     6301 gagctggtcg gcgagacgcc gagcgcgtac cgagcgcgct cgcacgacga gagcgcggtg
     6361 atccccgcgt gcgtggcgaa gcgtctgacc cggcccgccc ggcaccgcat acgcacggcg
     6421 gaacccggcg aagcgtccta gcgtgagcac atggctacga acgatcccca cgctatgacc
     6481 agactcccgg cgccggatgt gaagctcgcc cagtgcttcc tggccgtcga cgaccacgac
     6541 aaggcgctcg ccttctaccg cgacgtgctg ggcatggagg tccgcggtga cgtcggcttc
     6601 gaggggatgc gctgggtgac cgtgggctcc ccgctccaac cggacgtcga gatcgtcctg
     6661 gagccacccg ccgccgaccc cgacatctcc cccgccgacc gcgagaccat cgccaccctc
     6721 ctcgccaagg gcgtcctccg cggcgtcaac ttcaccacca ccgactgcga cgccctctac
     6781 gcccgcgtcg agtcctccgg cgccgacgtc ctccaggagc ccacggacca gccctacggc
     6841 gtccgcgact gcgccttccg cgacccggcg ggcaacatgc tccgcttcat ggaacgccgg
     6901 ccctgagccg acaccggccg gggtgaccgg cgggccgacg gaaacgtcgt tgcgtggggc
     6961 ggggcggcgg gagaccgtac gagtcgttca gtcggagggg ctggaccgtg cgagagggag
     7021 cggcgctgtg ggtggagtga gcgggagcgg tcacggggac gcgcgcgagg gtggaagccc
     7081 ggcggacggg gcgggcgggg cgatccggtg gacgtacgcc ttcgtcgacc ggccggcggc
     7141 cgggttcgag cgggcctgtg ccttctggac ggccgtcacg gcggccaagc tgtccgaacc
     7201 gcgaggcgag cggggtgagt tcgtgaccct gctgcccgag acgggcgacg cgtgcgtgaa
     7261 ggcgcaaggg gtcgcgtccg gtgacggcgg cgctcatctg gacttcgccg ccgaggacgt
     7321 acccgcgctc gtggaccggg cggtccggct cggcgccgag gtggtcaccc cgaacgacgg
     7381 ctgggcggtg ctgcgctcgc ccgccggaca tctcttctgc gtggtgccgt ggcacgggga
     7441 gtcggtacgg acgccggtgg tcgaggggag ccggctggat caggtgtgcc tggacgtgtc
     7501 accggccgag ttcgacggcg aggtcgcgtt ctgggcggcc ctgtcgggct gggactcccg
     7561 cgcgggctcc ctcccggagt tccacgtcct gcgcccaccg acgggtctcc ccatccgcat
     7621 cctcctccaa cgcctcgaca ccccccgccc cgcctccgcc cacctcgacc tcgcctgcgc
     7681 cgacatcgac gccacccgca cccgccacga acacctcggc gccacgttcg tggccggcca
     7741 cccgcactgg acggtgatgc gagacccggc gggcggcaca tactgcctga cgggccgcga
     7801 cccggaaacg ggcggattgc cacccagggc cgagtgacgc ggacgggtag ggcgccgcca
     7861 gcgggggcaa ccccgccccg gcggatcccg tcaggccttc ttttcggtgc tcgcctcagc
     7921 ggtctcagcg gtctcagcgg tcacctcgac ctgcttatct gcctccccca cgtgcacgtc
     7981 atgaccacca tgcgcgtcat gaccaccatg cgcgccatgg cttccgtgcg tccgccgggc
     8041 cacggcccgg ggcttctccg cggcggccgt ctgggcctcg acggcctcgt cgacgtacgc
     8101 ctcacatttg gggtttctgc acggccccgg actccacacg ggtacccacg cgcccagcgt
     8161 cttgtgccgc cgtacgaccg tggccaccgg ctgtccgcag accgggcaga cctgttcgtc
     8221 gatgcccatg cgtccagggt attgccgatg gcgccagggc gctccccgcc gcacacggac
     8281 catcggcgac cggccaggcg accatcgccc gcccggccgc tgggccgccc aggccgccgg
     8341 ccgacgcgac cccgccccgt cagcgcttcc tgctgtacgt ccgcaccagc accccgttgt
     8401 cgaagctccg cacctcgtcg agcgtgaact cggagacggc gaacccggag ccgaacatcg
     8461 gcataccggt gcccagcacg atcggatacg tcttgatgat cagctcgtcg atctcgtcga
     8521 ccagcgcgcc ggcgacggcc gagccgccgc acaggtagat gccgagtccc ccgtcctccg
     8581 ccttgagctc gcggaccttg ccgaccaggt cgtccgagat gatctcgacg ttcgggtcgg
     8641 gcgactcctt cagcgtgcgc gaggcgacgt actcgcgcag atgggcgaac gggctggtga
     8701 tgccctcctt cagcgccacg tcgtagctgg cgcggccctg gatgatcgtg tcgtagtcct
     8761 tgttcgccag accgtcggtg ccgatgagcc ggcgcacctg ggtcgggttg gtgtccgggt
     8821 gctccgcctt gaggtactcg gcgaagtcgc ccaccacgaa ggggtacatg aacgacgcgt
     8881 cgccgtccgc gtccccgatg aagccgtcga tcgaacaggc gatgaggtac gtcaacttgc
     8941 gcaaaccggt ctctttccct cgtccgacag gtgagtgctc ctgagccact cactcaacca
     9001 cgtcagttat agtacttcaa ctgtagtggt tgcaagggat tcagatactc caggaactga
     9061 ggagcgcgga tggtcaggaa cccggaacgc agggccgctc tgctggacgc ggcggtggcg
     9121 gtgctggcgc gggaaggagc gcgcgggctg acgttccgcg cggtggacgc cgaggccggc
     9181 gtgccggtgg gcaccgcgtc caactacttc gccgaccgcg acgccctgct ccaccagatc
     9241 gacacccggc tgcaggagcg gctgaccccc gacccggccg tggtcgagga actgctcaag
     9301 gcgccgaagg accgctccct ggtcatggct ttcatgcgcg acctactggc ccgtgtgacc
     9361 ggggaccgca ccggctatct cgcgcatctg gaactgcgcc tcgaagccac ccgccgcccc
     9421 gccctgcacg cctcgtacac cgagtcggtg cgcggagagc tggattttgg gatgagcttc
     9481 caccgcgagg cgggcctccc cggaggcgac gagaccgtca tggtcctcta cctggccatg
     9541 cagggcctcc tcctcgaaca cctcaccctg cccgacgtcc tcgacaacgc cctccccggc
     9601 gtccccgccc ccgaaggcct gatggaacgc atcgtggaat cgatcgtccc cgagcactga
     9661 cgccccgaaa ggggcgcggg gaactgcgcg agcaaccaca acgcacccgc acccgcaccc
     9721 gcacccgccg aacaacccac atcccccgag ctctgaggcg taaggggaag ggggtcgcag
     9781 gggcgcagcc cctggggatg ggacgggtag gggcggcggg ggcgaacccg aaaaccggcg
     9841 ggccccgcac accgtgggga tgtgcgggac ccgccggcca tccgaaggca ccggcacggc
     9901 accgggtcag gtcagcaccg cgccagcgcc tccggagcct caagcgggcg ggtgttcgca
     9961 cccgcgccac cggcggtcgt ggaggccact cggccccacc tcagctgctg cgacgcgtca
    10021 cgaactcggc cagcgcgaga agcccgccgg ccgactccgg gtccggtacc gcacgggaca
    10081 gttcgtgcat ggcccgggcc atacgatcgg ccgcctggat ctgcgcccag tcacgaccac
    10141 cggcccgctc cacgaccagc gccgtacgct ccaggtcccc ctcctcgtac ggcagcccgt
    10201 acaactcggc gagttcggcg gcctccgggg tgccggaggc gagcgcggcg accaccggga
    10261 gggacttctt gcggaccatg aggtccgccc cggccggctt gccggtgcgg ctcgggtccc
    10321 cccagatgcc gatcacgtcg tcgatgagct ggaaggccag cccggcctcc cgcccgaacg
    10381 cgtcgagggc ctggacgtcc tcctcaccgg cccccgcgta caacgccccc agcgcgcagg
    10441 cgcagccgag cagcgcgccc gtcttcgcct cggccatggc gagcacctcg tcgagggtga
    10501 cgtcctgcgg acggcgtcct tccatctcgg tgtccgtgtg ctgtcccgcg cacagttcga
    10561 cgacacagga cgcgagccgc gcggcggccg ccgccgacgc cggatgcggg tcctcagcga
    10621 gcagctgctg ggccagggcc tgcagcgcgt ccccggcgag gatcgcgtcg gggatcccga
    10681 acacggtcca cgcggtggcc cggtgcctgc gggtggtgtc ccggtccatc acgtcgtcgt
    10741 ggagcagcgt gaagttgtgc accagctcca ccgccgcggc ggcccgtacg gcggcggact
    10801 cgcggccgcc gagcgcggcg accgcggcca ggaccagcgc gggccgtatc gccttgcccg
    10861 cgttccccgc ggccggtgtg ccgtccgcgt gctcccagcc gaagtggtag cgcgcgaccc
    10921 ggcgcatcga gccgggcaac gacccgacgg cccggcgcag ttcggggtcg acggacaccc
    10981 gcgcctgctc caggatctcc gccgcctcct gcccgtcgaa cgcactcacc gcccccgacc
    11041 gaccgaccgg cccccgaaca ccggcagcag cccctggcat caccggcccc accgcatcgg
    11101 ccgactcccc accctccgcc gattcaccga ctccagccga atccccgccg ctctccggat
    11161 ccacggccct cgccggctca ccgactcccg ccgatcgcgc cgctcccgcc gagcccaccg
    11221 ctcccgtcgg gtctgcggga ctcgtgatgg ggctccgcct ttccgggatc tcgccttgca
    11281 gagtcccgcc gtgtccccgc cctgacgggc ggggacacgg cgtccggtcg gacaaggtca
    11341 ccgccagcgg ccgatctcga cgttctccag aacgccgagc gcgtcgggga ccaggaccgc
    11401 ggccgagtag taggccgtca cgaggtactt gatgatcgcc tgttcgttga tgcccatgaa
    11461 gcgcacggac aggctgggct cgatctcgtc cgggatgttc gcggcccgca gaccgatgac
    11521 gccctggtcc tcctccccgg tacgcatggc gatgatcgac gtggtcctgg cctcggtcac
    11581 cgggatcttg ttgcacgggt agatcggcac gccgcgccag gtcgggatgc ggttcccggc
    11641 gatgtcgatg gtctcgggga cgagtccgcg cttgttgagc tcgcggccga acgcggagat
    11701 cgcgcgcggg tgggcgagca gcagcttggt gccccggcgg cggctgagca gttcgtccag
    11761 gtcgtcgggg ctgggcacgc cgtcgtgcgg ctggagccgc tggtcgtact cgcagttgtg
    11821 gaggaggccg aactcgcggt tgttgatgag ctcgtgctcc tggcgctcct tcaacgcctc
    11881 gacggtcagc cggacctgct gctcggtctg gttcatcggc tggttgtaga ggtcggccac
    11941 gcgcgtgtgg atgcgcagca cggtctgggc gacgctcagt tcgtactcgc gcggcgcggc
    12001 ctcgtagtcg acgaaggtgt gcgggatgtc cggctcaccg ctgtggccgg cggcgaggtc
    12061 gatctccttc tcgccgtact tgttggtgcg ctgcgacggg atggaacgct gctcctgaag
    12121 gtgctcgctc agggtctcgg cgcgctccga gatctgctcg acggccgcac gcggcaggac
    12181 cagtaccgtg cacgcggtga ccgcgcgggc cgtgtactcc cagatcgcgt cggggtcgag
    12241 cagcgactgg tcgccgaagt aggccccgtc tgccagcaca ccgaggaccg cgtcgtcgcc
    12301 gtagggtccg gtgccgatct tctcgacctt gccgtgcgcg agcaggaaca cctcctcggc
    12361 atggctgccg aactcggcca gcacatcacc gggcgagaac tcccgctgct cgcaccgctg
    12421 ggccagctcg cccagcacgt cgatgtcctc gtaagtccgc agggccggca gttcgcccag
    12481 ttcggcgggg atgacggcga cccggtcgcc ggtcttcaca aaagtgacgc ggccgtcgcc
    12541 gaccgcgtag gtgagccgcc tgttcacccg gtatgtgcca ccctgcacgt tcacccaggg
    12601 cagggtgcgc agcagccagc gggagctgat ctcctgcatc tgtggtgtgg acttcgtggt
    12661 ggtggccagg ttgcgggcag cggccgtgcc gagactctgc tgcggcctgt cctgctgcga
    12721 gcgaacctct tcgcctaccg acatacggat tcccctccgg gtgcactgat atcgcggtca
    12781 ccgatctcgc gacccagcct cccaccgcgg aatgtgccgg tgctattacc cgaaagagcg
    12841 ggaatggatc ttagaagtct gggcatatca ggggactttg tcgacgatcc gcgcgccggg
    12901 cgggctcctc gccgaatctg accggatcga ctcgcacgtc ccaccgtcaa ctggctccca
    12961 ccgggcgttg ggagtacaag cctgcgtacg aggcggccac gaccagcggc cgtcgcaccg
    13021 tacgaaggag tcggccatgg ccccacccat gtccgcggga agatttctca ccgtcctcaa
    13081 gaacgagggc gtccgggtcg tcgaggtcgg cgactgggaa catcacaacc gcaaccacaa
    13141 gggcccctgg ggacccgtcc acggcgtgat gatccaccac accgtcacct ccggcagcga
    13201 acgcaccgtc cgcatctgcc gcgacggcta ctcgggcctg ccgggcccgt tgtgccacgg
    13261 cgtcatcacc aaggacggcc gggtccacct cgtcggttac ggccgcgcca atcacgccgg
    13321 tttcggcgac gacgacgtcc tgcgggccgt gatcgccgag aaggccctcc cgctggacaa
    13381 cgaggccaac accgacggca accggcactt ctacggtttc gagtgcgaga acctcggcga
    13441 cggcaaggat ccctggccca aggcccaact cgacgccatc gagagggtct ccgcagccat
    13501 ctgccgtcac cacggctgga accagcggtc cgtcatcggc catctcgaat ggcagcccgg
    13561 caaggtcgac ccccggggct tcaccatggc ctccatgaga gagcgaatac gggcccgcct
    13621 gaagtaggga cccgatcgtg ggcggccccc ggcgccggcc ggtcatgtgt ccgacaatgg
    13681 gcggatgacc ggccatcccc gcgcccccga ccccgacccc gccaccgccc tgcgcccccg
    13741 gctgccgtcc cccctccagg aggtcgcgga cgaccgcttc gcccgccacg gcgtccggct
    13801 gctcctcaag cgcgacgacc tgatccatcc gcagctcatc ggcaacaagt ggcgcaagct
    13861 cgtccccagt ctgcgcgcgg cggccggccg tccgctgctc accttcggcg gcgcctactc
    13921 gaaccatctg cgcgccaccg ccgccgcggg ccgcctcctg ggcgtgccca ccatcggcgt
    13981 ggtccgcggc caggagctgg ccgaccgccc cctcaacccg tccctggccc gctgcacggc
    14041 cgacggcatg cggctccact tcgtcgacag atcgacgtat cgccacaaga ccgacccggc
    14101 caccctggcc gccgtgctcc gcgccgccgg cgccgaggac gcctatgtcg tccccgaggg
    14161 cggcagcaac gccctcgccg tacgcggctg ccaggatctc ggcacggaac tgcgcggccg
    14221 ggccgacgtc gtggccatcg cctgcggcac cggcggcacc ctcgccggtc tggccgccgg
    14281 tctggccccc gaccagcgcg ccctcggcat ccccgtcctc aagggcggct tcctcgaaga
    14341 ggagatacga agactccagg accaggcctt cggcggcccg cgcggcgact ggcggctcga
    14401 cgagcgcttc cacttcggcg gctacgcccg caccacgccc gagctggacg ccttcgccgc
    14461 cgacttcgag acccgccacg gcctccccgt ggaacgtctc tatgtcgcca agttgctcca
    14521 cggacttgtc accctcacat cggaaggcgt cttcccgcgc gggacgacga tcaccgcggt
    14581 gatcacaggg cgcccgttct aggacgcctc gcggtagacc gcggcctcct ccaggtccag
    14641 tctccgcagc agcgtgcgca gcatctcgtc gtcgatgtag cggccgtccc gcagcctcac
    14701 gaacatctcg cgctcggcgc cgatcatctc ccgggagagg cggctgtaga cgtcgtcgac
    14761 gctctccccg gtcaccgggt tcaccgcgcc gagccgctcc cagaccgcgt tgcggcgccg
    14821 ttccaggacc gtacggagac ggtcgacgag cggcggcggc agctcgttgc tctcgttcgc
    14881 gaggagttcg tcgaggcggg cctcggcggc ccgggacgcc tgggcctggg cgttggcctc
    14941 ggcgagcgtc tcggcctgct ggtcgcgtcc cggcagcttc agcacccgga tcagcggcgg
    15001 cagggtcaac ccctggatga ccagcgtccc gatgaccgtc gtgaaggtca ggaagaggat
    15061 caggttccgc tcggggaagt cctccccgcc gtgcaccgtg agcgggatcg agaaggcgat
    15121 ggccagcgag acgacgcccc gcatgccggc ccaggccacg acgaacggcc ccttccaggt
    15181 gggattgccc tcccgttccc ggatccgccg ggacagcatc cggggcagga aggtcgctgg
    15241 atacacccat atgaaccggg acgcgacgac gacgaggaag acggccacgg cgtaccagcc
    15301 ggcgcgcacc ccctcgtact cgcccagtcc ttcgaggacg acctggagct gcagtccgat
    15361 gagggcgaac acggcggact ccagcaggaa ggcgaccatc ttccagacgg cctcctcctg
    15421 gaggcgggtg gcgaagtcga cctgccagtt gcggtggccg agatacaggc cgacgacgac
    15481 cacggcgagc acgccggagg cgtgcaccca ctcggcgagc ccgtaggcga cgaaggggat
    15541 cagcagggag agtgtgttct gcagcagcgc ttccttcagg tgcgtgcgca gccagtggat
    15601 cggcatcatc agcagcaggc ccaccgcgac gccgccgacc gccgccacca ggaactcgac
    15661 gatcccgccg gtccagctcg cgccctcgcc gacggcggcc gcgagggcca cccggtaggc
    15721 ggtgatcgcg gtcgcgtcgt tcaccaggga ctcgccctgc aggatcgtgg tgatccgcga
    15781 cggcagcccc acccgccggg cgaccgccgt cgccgcgacc gcgtccggcg gcgccacgat
    15841 cgcgcccagc accagcgcgg cggtcagcgg cagccccggc acgatcatgt acgcggccca
    15901 gcccacggag agggtggcga agagcacgta gccgaccgac agcagcgcca cgggcctcag
    15961 ttgggcccgc agatcgaggt aggagctgtc gccggcggcc gtgtacagca gtggcggcag
    16021 gatcagcggc aggacgatct cggggtcgag ctcgtagtgc ggcacgccgg gcaggtacga
    16081 caccacgagc cccaccgcga ccagcagcag cggggcgggc accggcgtac gccgggcggc
    16141 tccggcaacc gtcgcgctcc ccgcgaccag caacagcaag ggcaaaaagt gcatcgcttc
    16201 ccgccgtctt cgtttccgcg cgaggtttcg cgcacccgtc gtaacctggc aatcatgaaa
    16261 cagtgcacgc acgcggacgc gctgccgcac cccgagcccg aacccctgag cgagacgtgc
    16321 ccggagtgcc tggccgccgg gagccacccg gtgcagttgc ggatgtgcct ggagtgcggg
    16381 cacgtgggct gctgcgactc ctcgccgatg cggcacgcga ccgagcacca caaggagagc
    16441 ggccatccca tcatgcgcac cttcgaagcg ggcgagtcct ggcgctggtg cttcgtcgac
    16501 catgtactcg tatgacccga aggagccgat cggacccgaa caggacccct ccgaacacgt
    16561 ccgcgacgtc gtacgacgga accatgtcac cccgtgacac gtcgacgtac tcgtgtgaca
    16621 aggttcggca gtccgacgcc tgggtacgtc aatccggcgc gcgctcttcc tatttgaggc
    16681 ccgcagacct ctagccaccg agcgtattca taggcttact atgagtgaca gcatggggtg
    16741 gggtctccag gaccctgagg acacggcact cgggagcgcg atagcgtcac cgctgaacca
    16801 cgtagcgcat tacccggggg gcgaccctcg gcccccgaag aagcttgtac caccttggag
    16861 gtgagggtgt cccagatcgc aggcgagccc gggacccagg acttcgtgga agtccggctg
    16921 ccggccgcgg gtgcctacct gtcggtgctg cgtacggcga cggccggcct cgcggcccgt
    16981 ttggacttca ccctcgacga gatcgaggac cttcgcatcg cggtcgacga ggcctgcgcg
    17041 atcctgctcc agcaggccgt gcccggctcg gtgctgagct gtaccttccg cctcatcgac
    17101 gattcgctgg aggtcacggt gtcggccccc accacggacg gccacgcccc cgcacgagac
    17161 accttcgcct ggaccgtgct gtcggccctg gcgggcaagg tctcctccgc ggtcgccgac
    17221 gacaaaaccg tttcgatcag cctctacaaa cagcgcggcg cgggacccgg gccggcgtga
    17281 ggaacgggga cggtccggtg cgggacgaag aacgcggcac acgggaactt cccgcggagg
    17341 atgacggcgg tccgagtgga ccggcgcatc tggcggacgg cgtcgacggc atccccgagc
    17401 aggcccggcc gcacccggag gacgactcct cggcggcggc cggagcgtct cggtgggcgg
    17461 agccggccga cggcgaggag cgcgaggcgc tctccgacgg gcaacgggat ccggagagtg
    17521 ccctacggag caccacgtcc tcacgagggc ggactggggc ctcccccgct cgagcacagt
    17581 cgagagctgg gggaacggtg acggcgggcg ggactatgag cgagcacgag cgacacgacg
    17641 aggcgggcgc gcagagcgtg cgaagcacgc agcacgaccc tcaggaccgc agcggggcgc
    17701 gagccctgtt cgtacagctg cgtgccctgc cggacggcag tgccgagtac gcggagctgc
    17761 gcaaccggct ggtccggatg catctgccgc tcgtggagca cctcgcacgc cgcttccgca
    17821 accgcggcga gccgctggac gacctgacgc aggtcgccac catcggcctg atcaagtcgg
    17881 tggaccgctt cgacccggac cgcggcgtgg agttctccac gtacgcgacc cccacggtcg
    17941 tcggcgagat caagcggcac ttccgcgaca agggctgggc ggtgcgggtg ccgcgccggc
    18001 tgcaggagct gcgcctcgcg ctgaccacgg ccacggccga gctgtcccag cagcacggcc
    18061 ggtccccgac ggtgcacgag ctggccgaga agctggccat ctcggaggag gaggtcctgg
    18121 agggcctgga gtcggccaac gcgtactcca cgctgtccct ggacgtcccc gacaccgacg
    18181 acgagtcacc ggccgtcgcg gacacgctcg gcgccgagga cgaggcactg gagggcgtcg
    18241 agtaccgcga gtccctcaag ccgctgctgg aggacctccc gccccgggag aagcgcatcc
    18301 tgctcctgcg cttcttcggc aacatgaccc agtcgcagat cgcgcaggag gtcggcatct
    18361 cccagatgca cgtctcccgc ctgctggcga ggacgctggc acagctgcgc gagaagctgc
    18421 tggtggagga gtagcggccc cgccccgtca ggggcgtggg gctgtatcgg cgcgcggctc
    18481 caccgtgcgg gcgcgcgcag ccaccgacgg tcgccgcttc cctgccgcgc tccggcggag
    18541 cgctatcgct tcgtctcctc cgcccggccc ggcccctgga ttccgagggc ctgggtcgtc
    18601 gcgggattga tcagcaggac cagtgcggcg acggcgacgg cggccagcac gatgcccgcc
    18661 gggatcgaca ggctgtcggc gcgcagcagg ttgtaggcca ccggcagcgc catgatctgg
    18721 gtgatcacgg cgggcccccg gctccagccg cgccgcagca gcagcccgcg ggcggcgatc
    18781 agcggcagca gggccagcgc gatgagcgtg atgcccccgg tgacaccggt gctcaggtcg
    18841 ccggagtcgc cggtgaagcc caggacgagc atcgctccgc cgcccaccag cagggccacc
    18901 ccctccagcg cggccagcgc ggccgcggcg gtcagccgcc cggggcgggg ctcggcgtcg
    18961 gaggtgtccg gtgtggggtt ctgctcaggg ctcacccctg aagggtagcc gtcgcccgag
    19021 ggcccgcccc ggccccggta cccgctccgg cgcccggcac acacggtgcc gccgcgcgcc
    19081 ctcacgtgct catcgtcact acccgatctc ccgcttgatc cgcacctcgg tatggggcga
    19141 gtaccaccca gtaggtaccc tgcaatccat gcgtgcactt ctcgtggtca atccggcggc
    19201 aaccaccaca agcgcacgta cgcgcgatgt gctgatccac gctctcgcga gtgagatgaa
    19261 gctcgaggcg gtcaccacgg agtaccgggg tcacgcccgg gacctcgccc gccgggcggc
    19321 ggagggcaag gacgacatcg agctcgtcgt ggcgctcggc ggcgacggca cggtcaacga
    19381 ggtcgtcaac ggcctgctgc accacggacc cgaccccgac cgcctccccc gtctcgccgt
    19441 ggtccccggc ggttccacca acgtcttcgc ccgcgccctc ggcctgccga acgacgcggt
    19501 ggaggccacg ggcgtcctgt tggacgcgct gcgcgagagc cgggagcgca cggtcggcct
    19561 gggtatggcc tcgggcaccc cgggcacgga ggacgaggcg gtgccgtccc gctggttcac
    19621 cttctgcgcc ggcctcggat tcgacgcggg tgtgatcggc cgggtcgagc aacagcggga
    19681 acgcggacgg aaatccacac acgctcttta cctgcgtcag gtattccggc agttcctgga
    19741 ggagccccac cgcaggctcg gcacgatcac tttggagcgg gccggcgaag aaccgatttc
    19801 cgatcttgtg ctgtccatag tctgcaacac gtccccgtgg acgtttctgg gcaatcgccc
    19861 ggtgtacgcg tcgcctaagg cctcgttcga taaaggcctc gacgtgctcg gtctcagccg
    19921 catgtcgacg cccgcggtcg cccgatatgg cacacagttg ctcacttcgt cccccgagcg
    19981 cggacctcgc ggcaagcacg ccaccactct gcatgacctg accgacttca ccttgcattc
    20041 gaaggccccc ctccccctcc agatggacgg cgaccacctc ggactgcgta cgagcgtgac
    20101 gttcacaggc gtacgccgtg cactgcgtgt gattgtgtga gcggaacggg caaaagtcct
    20161 tccactcgaa cgtttaggcc agggtccacc ccatggaagt acggctgtga cacagtcgac
    20221 accgaggaat caaaaaaaac tttccggaag gggttgtatc cgccgctgag gtttgcgagt
    20281 ctctacgtgg cgctcgggac agcccgcaac atcggctccg caaagagcgc cggaacccct
    20341 cctcaaatca caggaccaca ccagtccgtc tggtgatcgg cccttcactt gttgagggat
    20401 tcgtgaaagc gttcacattc acaagcaacg tgcatgtaat accaaggaga ggtagcagcc
    20461 atggactggc gtcacaacgc cgtttgccgc gaggaagacc ccgagctctt cttccccatc
    20521 ggcaacaccg gtcctgcgct gctgcagatc gaggaagcca aggctgtctg ccgtcgctgc
    20581 ccggttatcg agcagtgtct gcagtgggcg cttgagtccg gccaggactc cggcgtctgg
    20641 ggtggtctca gcgaggacga gcgccgcgcc atgaagcgcc gcgccgcccg caaccgggca
    20701 cgtcaggcat ccgcctgaca tcccacccag caatagcctg agcttggcgg cgcgcacagc
    20761 gagtgcgctt ctcccgcccc cgagccgcag cgcgcagtgc ccccggtgcg cttaatcagc
    20821 cacgagcccg agccccggac cacaccatgg tccggggctc ggtgctgttt gcgatgccga
    20881 attccctacg ccggtcgcgg tgaccgcgaa gcatgcgtcc gacgtattcc ggtggccggt
    20941 gtctccccca ccgctacttc tgggcgcgca ccgggatgtc gaggatcacc tgggtgccgc
    21001 gctcgggggc ggggaccatg tcgaaggtg
//
