LOCUS       NZ_CP102512            21833 bp    DNA     linear   CON 11-FEB-2024
DEFINITION  Streptomyces sp. CA-210063 chromosome, complete genome.
ACCESSION   NZ_CP102512
VERSION     NZ_CP102512.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CA-210063
  ORGANISM  Streptomyces sp. CA-210063
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10859970)
  AUTHORS   Nielsen,J.B., Gren,T., Mohite,O.S., Jorgensen,T.S., Klitgaard,A.K.,
            Mourched,A.S., Blin,K., Oves-Costales,D., Genilloud,O., Larsen,T.O.,
            Tanner,D., Weber,T., Gotfredsen,C.H. and Charusanti,P.
  TITLE     Identification of the Biosynthetic Gene Cluster for Pyracrimycin A,
            an Antibiotic Produced by Streptomyces sp
  JOURNAL   ACS Chem Biol 17 (9), 2411-2417 (2022)
   PUBMED   36040247
REFERENCE   2  (bases 1 to 10859970)
  AUTHORS   Joergensen,T.S., Gren,T., Blin,K. and Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2022) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 05-AUG-2022
            Assembly Method :: Flye v. 2.9-b1768; Polypolish v. 0.5.0; POLCA
            polisher from MaSuRCA v. 4.0.5
            Assembly Name                     :: M642_aaa1.6.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 55.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 11:12:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,501
            CDSs (total)                      :: 9,410
            Genes (coding)                    :: 9,051
            CDSs (with protein)               :: 9,051
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 359
            CDSs (without protein)            :: 359
            Pseudo Genes (ambiguous residues) :: 0 of 359
            Pseudo Genes (frameshifted)       :: 141 of 359
            Pseudo Genes (incomplete)         :: 302 of 359
            Pseudo Genes (internal stop)      :: 23 of 359
            Pseudo Genes (multiple problems)  :: 101 of 359
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:19:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2460624
            Orig. end                         :: 2482457
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102512.1.
            Bacteria and source DNA available from Tilmann Weber, Dr.
            Professor, Novo Nordisk Foundation Center for Biosustainability,
            Kemitorvet, 220, 327D 2800 Kgs. Lyngby, Denmark.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21833
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="12"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21833
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21833
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11833](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11833)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(377..389)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    complement(377..392)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.45"
                     /tool="antismash"
     gene            complement(1300..3678)
                     /locus_tag="JIX56_RS10650"
                     /old_locus_tag="JIX56_10650"
     CDS             complement(1300..3678)
                     /GO_function="GO:0003959 - NADPH dehydrogenase activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445229.1"
                     /locus_tag="JIX56_RS10650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_10650"
                     /product="bifunctional salicylyl-CoA
                     5-hydroxylase/oxidoreductase"
                     /protein_id="WP_257550810.1"
                     /transl_table=11
                     /translation="MPPSPVIPTSGAAESGARGTARPATTTPQPPTRTSHPHRIAIIGG
                     GPGGLYSAALLKRLDPTREITLWERNAPEDTFGFGVVLSDETLGGIEHADPVVYEALQA
                     HFTRWDAIDIVHRNTRHTAGGHGFAALGRRRLLQILHDRCHALGVELRFRTEAPYPAWL
                     RETYDLVIAADGVHSATREAYAEVFRPAVEEHRCRYIWLAADFAFEAFRFEIAETEHGV
                     MQLHGYPYSQDASTVIVEMREEVWRAAGFGELDASASIERCAKLFADALGGRPLRSNNS
                     TWTTFRTVVNERWSHGNLVLLGDAAHTAHFSIGSGTKLAVEDALALAACLEEQPDLEGA
                     LTAYEEERRPVVASTQRAARASLEWFENIGLHLGQPARQFAFNLLTRSRRVTHDNLRLR
                     DAHFTDAVEREFGCPPGTPPMFTPFRLRGLTLRNRVVVSPMDMYSAADGVPGDFHLVHL
                     GARALGGAGLVMTEMVCVSPEGRITPGCAGLWNSRQAEAWRRTVTFVHEQAPGTAIGVQ
                     LGHSGRKGSTKLMWEGMDEPLDADNWPLTAASPIPYKPGSQTPRELSRAQLTDIREQFA
                     SAAGRAARSGFDLLELHCAHGYLLSGFLSPLTNRRTDRYGGSLDRRLRFPLEVFDAVRS
                     VWPQERPMTVRISATDWADGGTTADDAVEIARAFAAHGADAIDVSTGQVVADEHPEYGR
                     SYQTPFADRVRHEVGVPVIAVGAISSWDDVNSLILAGRADLCALGRPHLYDPHWTLHAA
                     AEQSYTGPAVTWPAPYRAGSRRPNTGRTDAPKPRLKLGS"
     gene            complement(3678..4505)
                     /locus_tag="JIX56_RS10655"
                     /old_locus_tag="JIX56_10655"
     CDS             complement(3678..4505)
                     /NRPS_PKS="Domain: ECH (20-267). E-value: 1.1e-49. Score:
                     160.9. Matches aSDomain:
                     nrpspksdomains_JIX56_RS10655_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445228.1"
                     /locus_tag="JIX56_RS10655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_10655"
                     /product="enoyl-CoA hydratase family protein"
                     /protein_id="WP_257539541.1"
                     /transl_table=11
                     /translation="MSPFTGSAARTADWRHLRCVITDGVATVTLARPEKLNALTFGAYA
                     DLRDLLAELSREKSVRALVLAGDGRGFCSGGDVDEIIGATLAMDTAQLLDFNRMTGQVV
                     RAVRECPFPVIAAVHGVAAGAGAVLALAADFRVADPTTRFAFLFTRVGLSGGDMGAAYL
                     LPRVVGLGHATRLLMLGEPVRAPEAERIGLISQLTDEGSADEAAQTLAHRLAEGPALAY
                     AQTKALLTAELDMPLSAAVELDAATQALLMNGEDYAEFHAAFTEKRPPKWQGR"
     aSDomain        complement(3705..4445)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JIX56_RS10655_ECH.1"
                     /evalue="1.10E-49"
                     /label="JIX56_RS10655_ECH.1"
                     /locus_tag="JIX56_RS10655"
                     /protein_end="267"
                     /protein_start="20"
                     /score="160.9"
                     /tool="antismash"
                     /translation="ITDGVATVTLARPEKLNALTFGAYADLRDLLAELSREKSVRALVL
                     AGDGRGFCSGGDVDEIIGATLAMDTAQLLDFNRMTGQVVRAVRECPFPVIAAVHGVAAG
                     AGAVLALAADFRVADPTTRFAFLFTRVGLSGGDMGAAYLLPRVVGLGHATRLLMLGEPV
                     RAPEAERIGLISQLTDEGSADEAAQTLAHRLAEGPALAYAQTKALLTAELDMPLSAAVE
                     LDAATQALLMNGEDYAEFHAAFTEK"
     misc_feature    4621..4633
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.71"
                     /tool="antismash"
     gene            4796..5260
                     /locus_tag="JIX56_RS10660"
                     /old_locus_tag="JIX56_10660"
     CDS             4796..5260
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312159.1"
                     /locus_tag="JIX56_RS10660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_10660"
                     /product="ATP-binding protein"
                     /protein_id="WP_257539549.1"
                     /transl_table=11
                     /translation="MTCSMNGSTALQEPPAPASWRIALPHTAAAVPVARALVRTALTAL
                     EHGTDRDTAELLTAELVANAVEHATGDGPIELVVELLPSGCKVEVHDPDPAPPGDLTTP
                     GHIEPDPWQEHGRGLLLIRALSSACGHRPTGSGKAVWFRLPTVPSQRRPA"
     gene            complement(5273..6283)
                     /gene="argF"
                     /locus_tag="JIX56_RS10665"
                     /old_locus_tag="JIX56_10665"
     CDS             complement(5273..6283)
                     /EC_number="2.1.3.3"
                     /GO_function="GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /gene="argF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675590.1"
                     /locus_tag="JIX56_RS10665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_10665"
                     /product="ornithine carbamoyltransferase"
                     /protein_id="WP_257539551.1"
                     /transl_table=11
                     /translation="MATVPHALAGRHFLKELDFTAEEFRGLIALAVELKAAKKAGTETQ
                     HLRGRNIALIFEKTSTRTRCAFEVAAADQGARTTYLDPSGSQMGHKESVRDTARVLGRM
                     FDAIEYRGDSQANVEELAAYAGVPVYNGLTDDWHPTQMLADVMTMTEHSDKPLDEMVFA
                     YLGDARFNMGNSYLVTGALLGMDVRIVAPQAYWPAEEIVTHARKLAEISGARITLTEDV
                     PEGVAGADFVATDVWVSMGEPKEVWDERIGALAPYAVTMDVLRATGNADVRFLHCLPAF
                     HDLGTKVGREIHERHGLDSLEVTDEVFESAHSVVFDEAENRLHTIKAVLVATLGR"
     gene            complement(6369..7592)
                     /locus_tag="JIX56_RS10670"
                     /old_locus_tag="JIX56_10670"
     CDS             complement(6369..7592)
                     /EC_number="3.5.3.6"
                     /GO_function="GO:0016990 - arginine deiminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125172.1"
                     /locus_tag="JIX56_RS10670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_10670"
                     /product="arginine deiminase"
                     /protein_id="WP_257539553.1"
                     /transl_table=11
                     /translation="MGFHVDSEAGRLRRVILHRPDLELKRLTPSNKTTLLFDDVLWVRR
                     ARAEHDGFADVLRDRGVTVHLFGDLLTDVMRIPRARELVLDRVFDEKEYGPLATDHLRA
                     AFESLPLTELVEALIGGMTKREFLDAHMEPASVRFHVMELDDFLLDPLPNHLFTRDTSA
                     WIYDGVSINAMRWPARQRETVHFEAIYRHHPLFRDETFHIWSEGQADYPSTIEGGDVLV
                     IGNGAVLIGMSERTTPQAVEMLAHKLFAAGSAETIVALDMPKRRAFMHLDTVMTMVDGD
                     TFTQYAGLGMLRSYTIEPGVGEKELKVTDHPPEHMHRAIAAALGLNEIRVLTATQDVHA
                     AEREQWDDGCNVLAVEPGVVVAYERNATTNTHLRKQGIEVIEIPGSELGRGRGGPRCMS
                     CPVERSAV"
     misc_feature    7591..7611
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.81"
                     /tool="antismash"
     misc_feature    7655..7675
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: medium, score: 28.08"
                     /tool="antismash"
     misc_feature    complement(7689..7709)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: medium, score: 28.45"
                     /tool="antismash"
     gene            7745..8872
                     /locus_tag="JIX56_RS10675"
                     /old_locus_tag="JIX56_10675"
     CDS             7745..8872
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481790.1"
                     /locus_tag="JIX56_RS10675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_10675"
                     /product="SPFH domain-containing protein"
                     /protein_id="WP_257539555.1"
                     /transl_table=11
                     /translation="MADITRRLGWRHLRGAPTAHIRHHRSGRLVHDGPGLSFWYRSLTA
                     ALSEVPVDDRELAMTFHARTSDFQDVAVQATVTYRVSDPAIAAARLDFSIDPDTGVWRG
                     APLEQLSTLLTETAQQHALDVLARTTLASALVDGVAAVRERVAGGLAAEPRLPATGIEI
                     VAVRVVALRPEPEVERALRTPAREQIQQEADRATYERRAVAVERERAIAENELASQIEL
                     ARREEQLVEQRGTNARREAEEKAAADAVKAGSEAARTVRLTGAEAERTVKLAEAEAARS
                     VRLTEAEAARQVKLAEAEATAARAVGAARAEAQAAWLRVHAEVDAATLHALTGTRLAEN
                     LPRIESVTVSPDVLTGLLAKLGVGAGTGGSDGDSA"
     gene            8869..9768
                     /locus_tag="JIX56_RS10680"
                     /old_locus_tag="JIX56_10680"
     CDS             8869..9768
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114166.1"
                     /locus_tag="JIX56_RS10680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_10680"
                     /product="hypothetical protein"
                     /protein_id="WP_257539557.1"
                     /transl_table=11
                     /translation="MSLAPRVVLVHRTTEYEELVARHGTHGQAAFFLRSRGRDIEDVAE
                     RHRRERRALAEVTSSVPLTWRQARVQRGDLDRFLFAPEDVVVVVGQDGLVANVAKYLAG
                     QPVVGINPDPRRNPGVLVRHRPDQAGKLLATSLQRASSADELTMVEAVADDTQRLVALN
                     EIYLGAAGHQTARYRLGLDGDRGVVEPQASSGVLVGTGTGASGWIRSVWQERASELALP
                     GASEDRLLWFVREAWPSPVTGTSLVAGALAGGGRLSLTVESDRLIVFGDGMEGDALELT
                     WGQTVRVGVAGVRLRLVG"
     gene            complement(10001..11833)
                     /gene="uppS"
                     /locus_tag="JIX56_RS10685"
                     /old_locus_tag="JIX56_10685"
     CDS             complement(10001..11833)
                     /EC_number="2.5.1.-"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="uppS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481786.1"
                     /locus_tag="JIX56_RS10685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_10685"
                     /product="polyprenyl diphosphate synthase"
                     /protein_id="WP_257539559.1"
                     /sec_met_domain="phytoene_synt (E-value: 9.5e-28, bitscore:
                     96.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3e-12,
                     bitscore: 45.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRTTTRSVTRSGRERSALDAAYDECRRLVRTTRPTEHALMQLMP
                     PVARPACWALYAAFAYADDLLDSAEGTEQERARRLQEWRAALEADLTSGTSEDPIRLAL
                     TDAVWQWGLDLGDLLGALDAVQRDDGREGVATWQEWRERAHAQNISWPEQLMRMLVRCG
                     LPVPVRLRDLPGFTRFVDGLFLTDMLRDLPEDLDGGHIWLPAEVLDRFHVTPAELISRE
                     WTPAVQQLIAHLAGQAREWLEGSRRALRNTLPLGPAIVLDTAVELFTAELDALVRAGSA
                     VLHRPVRVPRHTEWRILGPARARAAVVWRLTLPPDREAAPARTATPADRTAADATEAAP
                     FTGPGRLTTRIAEPPLPPRPHRDGARPPEISAAQLPQHVAIVMDGNGRWATGLGLPRDE
                     GHRAGAVALRDVVQGALEIGLAHLTVYAFSTENWKRSPDEVSKLFAIMRAELLDGELLD
                     HDVRLRWVGSPDGLPDDVVEVLRAQEHATRHRTGLTLNVCVNYGGRAELAQAGAALARA
                     ALAGEVDPARVSEQLFAAHLPHHALPDVDLLWRTSGEIRTSNFLPWHAHYAELHFTDQP
                     WPDVDRRDLWEAVTAYTLRKRRKGAAVVAPPPHA"
     gene            complement(12073..14649)
                     /locus_tag="JIX56_RS10690"
                     /old_locus_tag="JIX56_10690"
     CDS             complement(12073..14649)
                     /GO_function="GO:0004113 - 2',3'-cyclic-nucleotide
                     3'-phosphodiesterase activity [Evidence IEA]"
                     /GO_function="GO:0051731 - polynucleotide
                     5'-hydroxyl-kinase activity [Evidence IEA]"
                     /GO_process="GO:0042245 - RNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122488.1"
                     /locus_tag="JIX56_RS10690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_10690"
                     /product="polynucleotide kinase-phosphatase"
                     /protein_id="WP_257539574.1"
                     /transl_table=11
                     /translation="MSETIKGRTLPVTDLSLVVLIGASGSGKSTFARRHFKPTEIISSD
                     FCRGLVSDDENDQSATKDAFDVLHYIAGKRLAAGRRTVVDATSVQQESRKQLIELARQH
                     DVLPIAIVLDVPEEVCAERNAGRTDRADMPRRVIQRHTRELRRSLRHLEREGFRKVHIL
                     RGVEDVENATIVTEKRFNDLTHLTGPFDIIGDIHGCASELESLLGKLGYVDGTHPEGRT
                     AVFVGDLVDRGPDSPGVLRRVMSMVGSGDALCVPGNHENKYGRYLKGRNVQHTHGLAET
                     IEQMEGESEEFKKQVREFIDGLVSHYVLDGGRLVVCHAGLPEKYHGRTSGRVRSHALYG
                     DTTGETDEFGLPVRYPWAEDYRGRAAVVYGHTPVPQATWLNNTICLDTGAVFGGKLTAL
                     RWPERELVEVPAERVWYEPTKPLATEAPGGHEGRPLDLADVHGRRVVETRHAGRVSVRE
                     ENAAAALEVMSRFAVDPRLLPYLPPTMAPTATSHIEGYLEHPAEAFKQYKEDGVARVVC
                     EEKHMGSRAVALVCRDADAARERFGDGGTSRSSAAESGGGPTGALYTRTGRPFFDDEAR
                     TELVLHRVREAMTAAGLWDELDTDWVLLDAELMPWSLKASGLLRTQYAAVGAASGAVFP
                     GALAALEGAAARGVDVGELLGKQRERAADAAAFTDAYRRYCWPTEGLDGVRLAPFQILA
                     VQGRSLAALPHDEQLALIDRLVEFDVSGLLQTTRRLFVDTGDEASVRAGVDWWLEMTGR
                     GGEGMVVKPVGAVVRSEAGRLVQPGIKCRGREYLRIIYGPEYTRPENLARLRGRFLNHK
                     RSLALREYALGLEALDRLAEGEPLWRVHEAVFGVLALESEPVDPRL"
     gene            complement(14646..16160)
                     /locus_tag="JIX56_RS10695"
                     /old_locus_tag="JIX56_10695"
     CDS             complement(14646..16160)
                     /GO_function="GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042245 - RNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125168.1"
                     /locus_tag="JIX56_RS10695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_10695"
                     /product="3' terminal RNA ribose 2'-O-methyltransferase
                     Hen1"
                     /protein_id="WP_257539576.1"
                     /transl_table=11
                     /translation="MFLTISTTGTPERPATDLGFLLHKHPDKTQAFSTSYGKAHVLYPE
                     ADAERCTAALLLEVDAVALVRRGKGKGRGGAPDAALAQYVNDRPYAASSLLAVALNDVF
                     SSAVRGHCKARPELPEQTRPLRVEIPALPARGGPDLVVKLFEPLGWTVTAEAVALDTAF
                     PEWGASRYVRLVLESESLTLAEALRHLYVLLPVLDDAKHYWVSSDEVDKLLRAGEGWLP
                     DHPEHKLITSRYLSRRWSLTRQAMERLELVRLAEADDSEVEEIDNAVEEGEVEETVDDA
                     VEQAVDGETEEKPTPLVVRRRDAIIAALKESGAARVLDLGCGQGQLVQALLKDVRFTEI
                     VGTDVSMRALTIASRRLKLDRMGERQASRVQLFQSSLAYTDNRLKGYDAAVLSEVIEHV
                     DLPRLPALEYAVFGSARPRTVLVTTPNVEYNVRWETLPAGHVRHGDHRFEWTREEFRTW
                     AATVAERHGYEVEFVPIGPDDPEVGPPTQMAVFKQRGTDEKEAKAA"
     gene            complement(16262..19123)
                     /locus_tag="JIX56_RS10700"
                     /old_locus_tag="JIX56_10700"
     CDS             complement(16262..19123)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024841.4"
                     /locus_tag="JIX56_RS10700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_10700"
                     /product="esterase-like activity of phytase family protein"
                     /protein_id="WP_257539577.1"
                     /transl_table=11
                     /translation="MPRHRRRVRRRHVALAGLTASALLGGVAFAGGFAADAAPEADSAP
                     KKTQNGITLLDTLTVPAGTTELGMPFGGLSGIDYDPKTHTYAALSDDRSENGKARFYSL
                     RLPLEDKEFAEDKPALDALTVLDDRTGEPFAPKAVDPEAIRWNPDGKGLLWTSEGASAS
                     GQPAFVRETSASGAHLRDLPLPKAYAPVRSESGTLTAGVRNNQALEGLTLTPDGREVVT
                     ITENALVQDGPAAGLTAKSPSRLLVTDRRTGEAEAEHVYEVDPISAAPTAPLPAPVGTY
                     AADRGVSEILAINKTDYLTVERSFASGVGFAIRLYWTTTRGATDVHGEDRLSGSERPMP
                     KKLLYDFTLSGTDADNVEGITWGPTLPDGSRTLVLVADDNFGFNGSVTKFHLLSVRPGV
                     LTGAFPVTPKQPSTVDVQLLSFNDFHGNLEPPTGRDANLGSKLDAKSTPVGGAEYLAAR
                     LKQLRAGTDASLTVAAGDVIGASPFLSGLFHDEPTVESMEKLHLDVTSVGNHEFDEGTE
                     ELLRIQHGGCHPEDGCYLEDEPYDGSAFPWLAANVLDRTTGEPLLAPTWVKKVDGVEVG
                     FIGMTLEGTPEVTGQSGIKSVRFTDEVETADAAARKLRRQGVEAIVVLLHEGGVQAGSY
                     GQCDGISGPIVDIAKHLDPAIDAVVTGHTHQPYICSLPDPAGNPRSVTSASSFGRVVTE
                     TRLPVDRRTGDVVRDQVAAMNHLVTRTVTKDADQTAVIDKWKALSAPLANRVVGSVTAD
                     ITRSETRDAESDLANLVADAQLAATSAPERGGAQIALMNPGGVRADLVHASSTGGEAPG
                     EITYAEAFAVQPFAGSLVSVDLTGARIEKILEEQFNDSGTRAPTLMLGVSKGLTYSFSR
                     SAPVGDRIDPSSIKLNGEPLKPDTTYRVTANTFLAAGGDGFTTFAEGGNTVGGGDDITA
                     LTDYLTAHSPVAPPGTDRVTELP"
     gene            complement(19222..20157)
                     /locus_tag="JIX56_RS10705"
                     /old_locus_tag="JIX56_10705"
     CDS             complement(19222..20157)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484210.1"
                     /locus_tag="JIX56_RS10705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_10705"
                     /product="ABC transporter permease"
                     /protein_id="WP_257539579.1"
                     /transl_table=11
                     /translation="MNSVLDVVLSSAFLAAVLRVATPYLLAAMGGLVAERAGISNIALE
                     GQMLSAACTGALVAGYSGSVAAGALAGVAVAVLLGVLLAALRLELGADAIIAGIGLNLL
                     ASGGTAYAVFTLLDDKGGTSGLKSGTLPTVTLPGIEHIPVVGEVLSGQNLVTWLAFLAA
                     PFVAWLFFRTRFGFHLRAVGEMPDAAASVGIAVRRVQYAGLALSGALAGLAGVFLSMGY
                     VSFFVRDMTAGRGFIALAAVFLGGLRPWGVFLAALGFGAAEALAVQLGTLDVPPQLVST
                     IPYAMTLLALALYAWRRKRRGVGEVAPASL"
     gene            complement(20154..21296)
                     /locus_tag="JIX56_RS10710"
                     /old_locus_tag="JIX56_10710"
     CDS             complement(20154..21296)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006374923.1"
                     /locus_tag="JIX56_RS10710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_10710"
                     /product="ABC transporter permease"
                     /protein_id="WP_257539612.1"
                     /transl_table=11
                     /translation="MTTSPPTTLIESEDRREYKATRRRGLAVDLSMTLATILAALVIGF
                     LVMLATGKDPIAAYEALLTGPLERSFRVGRWLEDATTLTLLGLSVAIPFRARQISLGAE
                     SQLYAGALAAATVAVFLPLPPVAAVIVPLVAAATAGAGMGFVPGSMKARLGANEIVATL
                     MLNAIVVRVYDYLVNGPLKEPGSSAVHSERIQPDSALTPLTDWLGIPFGRANVGFLLML
                     LTAVALWLLITRTPLGYRIRMTGSNPHFAEYGGIRVPRAIEWSFVIGGAVAGLAGAHLV
                     QGVYGRLEPGLAGSLAFEGIVVALLARNNPLVVVVAGLFYSYLRAGGDIMEQQTDVGTE
                     IVVVIQAVIVLLVTAQALPDLLKRRLARRQATAIGEAGAR"
     misc_feature    complement(21302..21311)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(21708..21722)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
ORIGIN
        1 ggtctgcggg ccgaacggga gcagggcatc accatcgacg tggcgtaccg ctacttcgcc
       61 acggccaagc gccggttcat cctcgccgac acccccggcc atgtgcagta cacccgcaac
      121 atggtgacgg gtgcctccac cgccgagctg gcgatcgtcc tggtcgacgc gcgcaacggg
      181 gtcgtggagc agacgctccg gcacgcggcc gtcgcggcgc tgctgcgcgt cccgcacgtg
      241 gtcctcgccg tcaacaagat ggacctcgtc gggtacgagg agaaggagtt ccgccggatc
      301 gtcgaggact tcgcgcggca cgcggacgag ctggggctgc ccggcttcac ctcgatcccg
      361 gtctcggcgc tggtcggtga caacgtcgtc gaccggtccg ggcggatgga gtggtacgac
      421 ggtccggcgc ttctggagtt cctggagagc gtgccggtgg gggtggagac ggcggacgct
      481 ccggcccgct tccccgtgca gtacgtgatc cggcacgacg aagtccggta ctacgccggt
      541 cagttggtgt cgggggcgct gcgggtgggt gaccgggtga ccgtccaccc gtcgggcgag
      601 acctccgaga tcacggagat cgacgtcctg ggtgagccgg cggaggtcgc gtacgcgccg
      661 cagtcgatca gcgtgcggct ggcggaccag cgggacgtct cccgtgggga catgatcacc
      721 gcggccgggg cggacgcgcc gacgctgacg caggacgtcc gcgcggccgt ctgccatctg
      781 gcggagcggc cgctgcgcgt gggcgaccgc gtactgctcc ggcacacgac ccgcaccgtc
      841 aaggccatcg tcaaggacct cggcggcttc cccgaactga ccacgaacga cctgggccgc
      901 gtggtgctgc gcacggccga gccgttggcc ctggacgact atgcggccgt acgacggacg
      961 gggtcgttca tcctggtcga cccggcggac ggggcgacgc tgacggcggg gatgacggac
     1021 ctgtcataac gtccgcgcac cacgctcgcc gtcatagctg tgggcaggcg tgccgctagg
     1081 ggcggcacgg gtgggcacag cggcacccgg caagcgccgg tgagcgaagc cgccccagag
     1141 gttcagggca cccccgggct actgccgggc ggggctcggg ggcgcttgcc ggcgctgaca
     1201 gggtgccgcc gcgcccgccc tcccccactc tcggcttcgc tcgagcggga ggtgccccca
     1261 tcgccccagc ggcacgatcg cccgcagttg ggggacgcct caactcccca gcttcaagcg
     1321 gggcttcggg gcgtccgttc ggcccgtgtt ggggcggcgg ctgcctgctc ggtagggggc
     1381 gggccaggtg acggccgggc ccgtgtagga ctgttcggcg gccgcgtgga gggtccagtg
     1441 ggggtcgtac agatgggggc ggcccagggc gcagaggtcg gcgcggcctg ccaggatcag
     1501 ggagttgacg tcgtcccagg aggagatggc gccgacggcg atcaccggca cccccacctc
     1561 gtgccggacg cggtccgcga acggggtctg gtacgagcgc ccgtactcgg ggtgctcgtc
     1621 ggcgacgacc tgcccggtcg agacgtcgat cgcgtcggcg ccgtgcgcgg cgaaggcgcg
     1681 ggcgatctcg acggcgtcgt cggcggtggt gcccccgtca gcccagtcgg tcgcggagat
     1741 acggacggtc atgggccgct cctgaggcca caccgaccgt acggcgtcga agacctccag
     1801 ggggaagcgc agccggcggt ccagtgaacc cccatagcgg tcggtgcggc ggttggtcag
     1861 cggtgagagg aagccggaca gcaagtagcc gtgggcgcag tggagttcga ggagatcgaa
     1921 tccgctgcgg gcggcacggc cggcggcgga ggcgaactgc tcccggatgt cggtgagttg
     1981 ggcacgggag agctcgcgag gggtctgact gcccggcttg tacgggatcg gggaggccgc
     2041 cgtcaggggc cagttgtccg cgtccagggg ctcgtccatg ccctcccaca tcagcttcgt
     2101 cgagcccttg cggccggagt ggcccagctg gacgccgatg gccgtgcccg gcgcctgctc
     2161 gtgcacgaac gtcaccgtgc ggcgccacgc ctcggcctgc cgggagttcc agagcccggc
     2221 gcagcccggg gtgatccgcc cctcggggct cacgcacacc atctcggtca tcacgagccc
     2281 ggcgccgccg agggcgcggg cacccaggtg gacgaggtgg aagtcgccgg ggacgccgtc
     2341 ggccgccgag tacatgtcca tgggggagac gacgacacgg ttgcgcaggg tcaggccgcg
     2401 cagccggaac ggggtgaaca tgggaggcgt gccgggcggg cagccgaact cgcgctccac
     2461 cgcgtcggtg aagtgcgcgt cgcggaggcg gaggttgtcg tgggtgacgc ggcggctgcg
     2521 ggtgagaagg ttgaaggcga actgccgggc gggctggccg agatggagcc cgatgttctc
     2581 gaaccactcg aggctggccc gtgccgcacg ctgcgtggag gcgacgaccg ggcgccgctc
     2641 ctcctcgtac gccgtcaacg ccccttccag gtcgggctgt tcctccagac aggcggccag
     2701 cgccagcgcg tcctcgacgg ccagcttcgt accggagccg atggagaagt gcgcggtgtg
     2761 cgcggcgtcg ccgagcagca ccagattgcc gtgcgaccag cgctcgttga cgaccgtgcg
     2821 gaaggtggtc caggtggagt tgttggagcg cagggggcgt ccgccgagcg cgtccgcgaa
     2881 gagtttcgcg caccgctcga tggacgcgga ggcgtccagc tccccgaacc ccgctgcccg
     2941 ccacacctcc tcgcgcatct ccacgatgac ggtggacgcg tcctgcgagt acgggtagcc
     3001 gtgcagctgc atcacgccgt gttcggtctc ggcgatctcg aagcggaacg cctcgaaggc
     3061 gaagtcggcg gcgagccaga tgtagcggca gcggtgttcc tcgacggccg ggcggaagac
     3121 ctcggcgtat gcctcgcgcg tcgcgctgtg cacgccgtcc gccgctatga ccaggtcgta
     3181 tgtctcgcgg agccaggccg ggtacggggc ctccgtgcgg aagcggagtt cgacgccgag
     3241 ggcgtggcag cggtcgtgga ggatctggag gagtctgcgg cggcccaggg cggcgaagcc
     3301 gtggcctccg gcagtgtggc gggtgtttcg gtggacgatg tcgatggcgt cccagcgggt
     3361 gaagtgcgct tgcagggcct cgtagacgac cgggtcggcg tgttctatgc cgcccagggt
     3421 ttcgtcggag aggactactc cgaagccgaa ggtgtcttct ggggcgttgc gttcccagag
     3481 ggttatctcg cgggtcggat cgaggcgttt gaggagggcg gcggagtaca ggccaccggg
     3541 accgccgccg atgatcgcga tgcggtgggg gtggctggtc ctcgtgggcg gctgcggggt
     3601 cgtcgtggct ggtcgcgcag ttccccgcgc ccctgactcc gctgcccctg aggtcggtat
     3661 gacaggcgag ggcggcatca gcggccctgc catttcgggg ggcgtttttc tgtgaacgcg
     3721 gcgtggaatt ccgcgtagtc ctcgccgttc atgaggaggg cctgggtggc cgcgtccagt
     3781 tccacggccg ccgacagggg catgtccagt tctgcggtca ggagcgcctt cgtctgggcg
     3841 tatgccaggg ccgggccctc cgccaggcgg tgggccaggg tctgtgcggc ctcgtcggcg
     3901 ctgccctcgt cggtgagctg gctgatgagg ccgatgcgtt cggcctcggg ggcgcggacg
     3961 ggttcgccga gcatgaggag gcgggtggcg tggcccaggc cgaccacgcg gggcagcagg
     4021 tacgcggcgc ccatgtcgcc gccggagagg cccacgcggg tgaagaggaa ggcgaagcgg
     4081 gtggtggggt cggcgacgcg gaagtcggcg gccagggcca ggaccgcgcc ggcacccgcc
     4141 gccacgccgt gcacggcggc gatcaccggg aacgggcact cgcgtacggc ccgtacgacc
     4201 tgcccggtca tccggttgaa gtcgagcagt tgggcggtgt ccatggcgag ggtggcgccg
     4261 atgatctcgt ccacgtcgcc gccggagcag aaccctcggc cgtcgccggc cagcaccagg
     4321 gcccgtacgg acttctcccg ggagagctcg gcgagcagat cgcgcaggtc ggcgtaggcg
     4381 ccgaaggtga gggcgttgag cttctcgggg cgggcgaggg tgacggtggc gacaccgtcg
     4441 gtgatcacgc acctcagatg ccgccagtcg gcggtgcggg cggcggagcc ggtgaaggga
     4501 ctcatgacgg gcggcctcct cgggggctac ctcgacgctg cggctacttc cctacctcac
     4561 gaagctatca ccgatatctg accgtcgtca cgagtgcgcg ataggccgtc ggtggcgtcc
     4621 gtgactcggt cacggacgtt cgacaggccg gtaacgacgg gctcggtcgt gcgcggcgga
     4681 acgttggcgt gggtagaccg cctggcaacg gggcccgacg gtcccgtacg gcgcccgccg
     4741 agcggccctg ccggtccgcg ccgtaccatt cgtcacgctg aaagcaggac gacccatgac
     4801 ctgctccatg aacggatcca ccgccttgca agaacctccc gcccccgcct cctggcgcat
     4861 cgcgctgccg cacaccgccg cggccgtgcc cgtggcccgc gcgttggtcc gtacggcgct
     4921 gaccgcgctg gagcacggga cggaccgcga cacggcggag ctgctcacgg cggagctggt
     4981 cgcgaacgcg gtcgagcacg cgaccgggga cgggcccata gagctggtcg tcgagctgct
     5041 gccgtccggc tgcaaggtgg aggtccacga cccggacccg gcacccccgg gcgatctcac
     5101 cacgccgggc cacatcgagc ccgacccctg gcaggagcac ggccgcggcc tgctcctcat
     5161 ccgcgccctc agctccgcct gcggccaccg ccccacgggc tccggcaagg cggtgtggtt
     5221 ccggctgccg acggtgccgt cacagcgccg ccccgcatag gccttcggtc tttcagcgcc
     5281 ccagcgtcgc cacgagaacc gccttgatcg tgtgcagccg gttctccgcc tcgtcgaaga
     5341 cgacggagtg cgcggactcg aacacctcgt ccgtgacctc cagcgaatcc agaccgtgcc
     5401 gctcatggat ctcgcgcccg accttcgtcc cgaggtcgtg gaaggccggc agacagtgca
     5461 ggaacctgac gtccgcgttg ccggtggcac gcagcacgtc catggtcacg gcgtacggcg
     5521 ccagcgcccc gatgcgctcg tcccagacct ccttcggctc ccccatcgag acccagacat
     5581 cggtcgccac gaaatcggcc cccgccacgc cctcggggac atcctcggtg agcgtgatcc
     5641 gcgccccgct gatctccgcg agcttgcgcg cgtgggtgac gatctcctcg gccggccagt
     5701 aggcctgcgg ggcgacgatc cggacgtcca tgccgagcag ggcgccggtg acgaggtagg
     5761 agttgcccat gttgaagcgg gcgtcgccga ggtacgcgaa gaccatctcg tcgagcggct
     5821 tgtcgctgtg ctcggtcatg gtcatcacgt cggcgagcat ctgggtgggg tgccagtcgt
     5881 cggtgagacc gttgtagacc ggcactccgg cgtacgcggc gagctcctcg acgttcgcct
     5941 ggctgtcccc gcggtactcg atcgcgtcga acatccggcc gagcacccgc gcggtgtccc
     6001 gtaccgactc cttgtggccc atctgcgagc cggacgggtc gaggtacgtc gtccgggcgc
     6061 cctggtcggc cgcggcgacc tcgaacgcgc agcgggtgcg cgtcgaggtc ttctcgaaga
     6121 tgagcgcgat gttcctgccc cgcaggtgct gggtctccgt cccggccttc ttcgccgcct
     6181 tcagctccac ggccagcgcg atcagcccgc ggaactcctc cgcggtgaag tccagctcct
     6241 tgaggaagtg gcgcccggcg agggcgtggg gaacagtcgc catgggggcg ctcctgggtg
     6301 tgacggggag ggtgactggg acagggacag cataaggaag gtggaagtct atacgacgtt
     6361 ccacatttct atacggccga tctctccacc ggacagctca tacagcgcgg cccgcccctc
     6421 ccccgcccca gctcgctccc cgggatctcg atcacctcga tgccctgctt gcgcagatgc
     6481 gtgttggtgg tggcgttgcg ctcgtaggcg acgacgacgc ccggttcgac ggcgaggacg
     6541 ttgcagccgt cgtcccactg ctcgcgttcg gcggcatgga cgtcctgggt ggcggtcagc
     6601 acccggatct cgttcagacc gagtgcggcg gcgatcgcgc ggtgcatgtg ctccggcggg
     6661 tggtcggtga ccttgagctc cttctctccg acgccgggtt cgatggtgta cgagcggagc
     6721 atgccgagtc cggcgtactg ggtgaaggtg tcgccgtcga ccatcgtcat gacggtgtcg
     6781 agatgcatga aggcccggcg cttcggcatg tcgagagcca cgatggtctc cgcggagccg
     6841 gccgcgaaga gcttgtgggc gagcatctcg acggcctgcg gggtggtgcg ttcgctcatg
     6901 ccgatgagga cggcgccgtt gccgatgacg aggacgtcgc cgccctcgat ggtggacggg
     6961 tagtcggcct ggccctccga ccagatgtgg aacgtctcgt cacggaagag ggggtggtgc
     7021 cggtagatcg cctcgaagtg gacggtttcg cgctggcggg cgggccagcg catggcgttg
     7081 atggagaccc cgtcgtagat ccaggcggag gtgtcgcggg tgaagaggtg gttggggagg
     7141 ggatcgagga gaaagtcgtc gagttccatg acgtggaagc gcacggaggc cggctccatg
     7201 tgggcgtcga ggaactcacg cttggtcatg ccgccgatca gcgcctcgac cagttcggtc
     7261 aggggcaggg actcgaaggc ggctctgagg tggtccgtgg cgagcgggcc gtactccttc
     7321 tcgtcgaaga cccggtcgag gacgagctcc cgggcgcgcg gaatccgcat gacgtcggtg
     7381 aggaggtcgc cgaagaggtg gacggtgacc cctcggtcgc gcagcacatc ggcgaacccg
     7441 tcgtgctcgg cgcgcgcccg gcgcacccac agcacgtcgt cgaagagcag cgtggtcttg
     7501 ttgctggggg tgagcctttt gagctcaaga tccggccggt gcaggatgac gcggcgcagg
     7561 cgcccggcct cggagtcgac atggaatccc atgtcctcat cctgaccatt cgggcgcgtg
     7621 ttcacccgcc ggtcgaccga atcggaaccc ttccatctcg tccccttgac gataagtggg
     7681 ccgcgccatt atcgtctaag tgacactaac aagtgtcgat cagccgtcac gagggggatc
     7741 atccatggcc gacatcacca ggcggctcgg ctggcggcat ctgcgcggtg cgcccaccgc
     7801 gcacatccgt caccaccgct ccgggcggct cgtgcacgac ggcccggggc tgagcttctg
     7861 gtaccggtcg ctgaccgccg cgctctccga ggtcccggtg gacgaccggg agctggcgat
     7921 gaccttccac gcccgtacgt ccgacttcca ggacgtggcg gtgcaggcca cggtgacgta
     7981 ccgggtgagc gacccggcga tcgccgccgc ccggctggac ttctccatcg accccgacac
     8041 cggggtctgg cgcggcgctc ccctggagca gttgtcgacg ctgctgaccg agacggccca
     8101 gcagcacgcg ctggacgtcc tggcccgtac gacactggcg tcggccctgg tcgacggcgt
     8161 cgcggcggtc cgcgagcggg tggcgggcgg gctggcggcc gagccccggc tgccggccac
     8221 cggcatcgag atcgtggccg tacgcgtggt ggcgctgcgg cccgagcccg aggtggagcg
     8281 ggcgctgcgt acgccggccc gggagcagat ccagcaggag gcggaccggg cgacgtacga
     8341 gcgccgggcc gtggccgtcg agcgggagcg ggccatcgcc gagaacgagc tggccagcca
     8401 gatcgaactc gcccggcgcg aggagcagtt ggtcgagcag cgcggcacga acgcgcggcg
     8461 ggaggcggag gagaaggccg ccgcggacgc ggtgaaggcg ggttcggagg cggcccggac
     8521 ggtacggctg accggggcgg aggccgagcg gaccgtgaag ctcgcggagg cggaggcggc
     8581 gcgcagcgtc aggctcaccg aagccgaggc ggcacggcag gtcaagctgg ccgaggcgga
     8641 ggccacggcc gcgcgggccg tcggtgcggc acgggccgag gcgcaggcgg cgtggctgcg
     8701 ggtgcacgcc gaggtggacg cggcgacgct gcacgcgctg accgggacgc ggctcgcgga
     8761 gaacctgccg cggatcgaga gtgtgacggt gtcgccggac gtgctgacgg ggctgctggc
     8821 gaagctcggc gtcggggcgg ggacgggtgg ttcggacggg gactccgcgt gagtctcgcg
     8881 ccgcgggtgg tgctggtcca tcgcaccacc gagtacgagg agttggtggc ccggcacggt
     8941 acgcacgggc aggccgcctt cttcctgcgg tcccgggggc gggacatcga ggacgtggcc
     9001 gagcggcacc ggcgggagcg ccgggcgctg gccgaggtca cgtcctcggt accgctgacc
     9061 tggcgtcagg cacgggtcca gcggggtgac ttggaccggt tcctgttcgc ccccgaggac
     9121 gtcgtggtgg tcgtcgggca ggacgggctg gtggccaatg tcgccaagta cctcgcgggg
     9181 cagccggtgg tggggatcaa ccccgatccc cggcgcaatc cgggggtgct ggtgcgccac
     9241 cggcccgacc aggcggggaa gttgctggcc acttccctcc aacgcgcctc ctcagccgat
     9301 gagttgacca tggtcgaagc cgtcgccgat gacacgcagc ggctggtggc gctcaacgag
     9361 atctacctcg gtgcggcggg gcaccagacc gcccggtacc gcctggggct cgacggcgac
     9421 aggggtgtcg tcgagcctca ggcctcgtcc ggggtgctcg tggggaccgg gaccggggcg
     9481 agcgggtgga tccggtcggt gtggcaggag cgggcgagtg agctggcgtt gcccggggcg
     9541 agtgaggacc ggctgctgtg gttcgtgcgg gaggcctggc cgtcgccggt gacggggacg
     9601 tcgctggtgg cgggggcgct cgcggggggt ggtcggctgt cgctcaccgt cgagtcggac
     9661 cggctcatcg tcttcgggga cgggatggag ggggatgcgt tggagttgac gtgggggcag
     9721 acggtgcggg tgggggtggc gggggttcgg ttgcggttgg tgggctgacg cgggggtcgc
     9781 ccccgccgcc cctacccgtc ccatccccag gggctgcgcc ccttcgaccc ccgtcgcgtg
     9841 cgttctttgg ctgcgggtgc gtgggggctg gtcgcgcagt tccccgcgcc cctaaaaacg
     9901 aaaagcacgg ggcgcagccc ctgcttttca ggggcgcggg gaactgcgcg agcaaccaca
     9961 cacgacccgc acccgcccac gaatccgcag ccccgagctc tcaggcgtga gggggcggcg
    10021 ccaccaccgc cgccccctta cggcgcttgc ggagcgtgta cgcggtgacg gcctcccaca
    10081 gatcgcggcg gtcgacgtcg ggccagggct ggtcggtgaa gtggagttcg gcgtaatggg
    10141 cgtgccaggg gaggaagttg gaggtgcgga tctcgccgct ggtacgccag aggaggtcga
    10201 cgtcgggcag ggcgtggtgg ggcagatgcg cggcgaagag ctgctcggag acccgggcgg
    10261 ggtcgacctc gccggcgagt gcggcgcggg ccaacgccgc gcccgcctgg gccagttcgg
    10321 cgcggccgcc gtagttgacg cagacgttga gggtgaggcc ggtgcggtga cgggtggcgt
    10381 gctcctgggc gcgaaggacc tccaccacgt cgtccgggag gccgtcgggg gaacccaccc
    10441 agcggagccg tacgtcgtgg tcgaggagtt cgccgtcgag gagttcggcg cgcatgatcg
    10501 cgaagagctt ggagacctcg tcgggcgagc gtttccagtt ctcggtggag aaggcgtaga
    10561 cggtcaggtg ggcgaggccg atctccaggg cgccctggac gacgtcgcgg agggcgaccg
    10621 ctccggcgcg atgcccttcg tcccggggca gtccgagccc ggtggcccag cggccgttgc
    10681 cgtccatgac gatcgcgacg tgctgcggca gctgggccgc ggatatctcc ggcgggcggg
    10741 caccgtcgcg gtgcgggcgc ggcggcaggg gcggttcggc gatccgggtg gtcagccgcc
    10801 ccgggccggt gaacggggcc gcctcggtcg cgtcggcggc cgtacggtcc gcgggggtcg
    10861 ccgtccgcgc cggggcggcc tccctgtcgg gcggcagcgt cagccgccac accacggcgg
    10921 cccgcgctcg ggccgggccg aggatccgcc actcggtgtg ccggggaacg cgtaccgggc
    10981 ggtgcagaac ggccgatccg gcccgtacga gcgcgtccag ctcggcggtg aacagttcga
    11041 cggcggtgtc gaggacgatg gcggggccca gcgggagggt gttccgcagc gcgcggcggg
    11101 agccctccag ccattcccgg gcctggccgg cgaggtgggc gatcagctgc tggacggcgg
    11161 gcgtccactc gcgggagatc agctcggccg gggtgacgtg gaagcggtcg aggacttcgg
    11221 cggggagcca tatgtgtccg ccgtcgaggt cctcggggag gtcgcggagc atgtcggtga
    11281 ggaacagccc gtccacgaag cgggtgaagc ccggcagatc ccgcagccgc acggggacgg
    11341 gcagtccgca gcggaccagc atccgcatga gctgttcggg ccagctgatg ttctgggcat
    11401 gggcccgctc ccgccactcc tgccaggtcg ccacgccctc gcggccgtcg tcgcgctgga
    11461 ccgcgtccag ggcgcccagc agatcgccga ggtcgagccc ccactgccac accgcgtcgg
    11521 tcagcgcgag ccggatcggg tcctcgctgg tgccgctcgt caggtcggcc tccagcgcgg
    11581 cccgccactc ctgaaggcgg cgagcacgct cctgctcagt gccctcggcg gagtcgagca
    11641 ggtcgtcggc gtaggcgaag gcggcgtaca gggcccagca cgcgggccgt gccaccgggg
    11701 gcatgagctg catcagggcg tgctcggtgg gccgggtcgt gcggaccaga cggcggcact
    11761 cgtcgtatgc ggcgtcgagt gccgatcgct ctcgcccgga ccgcgttacg gaccgcgttg
    11821 tggtgcgacg catgggaacc ccacatacct tcgaatggga ccgatggatg ggaccgactc
    11881 gggtgacagc gatcgcccgc gatgggccgc gatcactgtc ccccgagcac tgccggaacc
    11941 gctggaacca ttcgaacgca gtgcacggcc acgcctgccc gcgacattat cagccgcatt
    12001 gtcacccggc aggccggggt cccggccgtc acggacgagc cctcccggcc gtcacggagg
    12061 ctcccacgac cgtcacagac gggggtcgac cggctccgat tccagggcca gcactccgaa
    12121 caccgcctcg tgcacccgcc acagcggttc cccctcggcg agccggtcca gggcctccag
    12181 acccagggcg tactcgcgga gggcgaggga ccgcttgtgg ttgaggaacc ggccgcgcag
    12241 ccgggcgagg ttctcggggc gggtgtactc cgggccgtag atgatccgca ggtactcccg
    12301 gccccggcac ttgatgcccg gctggaccag ccgccccgcc tcgctccgta cgacggcccc
    12361 gacgggcttg acgaccatgc cctcgccgcc ccggccggtc atctccagcc accagtcgac
    12421 gccggcccgc accgaggcct cgtcgccggt gtcgacgaag agccgccggg tcgtctgcag
    12481 caggccgctg acgtcgaact cgaccagccg gtcgatgagg gccagctgct cgtcgtgcgg
    12541 gagcgcggcg aggctgcggc cctggacggc gaggatctgg aagggggcga gacggacgcc
    12601 gtccaggccc tcggtcggcc agcagtagcg ccggtaggcg tcggtgaacg cggccgcgtc
    12661 ggcggcccgc tcacgctgct tgcccagcag ctcgcccacg tcgacgccgc gtgccgccgc
    12721 accctccagg gcggccagcg cacccgggaa caccgcgccg gaggcggcgc cgacagccgc
    12781 gtactgggtg cgcagcagcc cggacgcctt cagcgaccag ggcatcagct cggcgtcgag
    12841 cagcacccag tcggtgtcca gttcgtccca cagcccggcc gccgtcatgg cctcgcgcac
    12901 ccggtggagg accagctcgg tgcgggcctc gtcgtcgaag aacgggcggc cggtacgggt
    12961 gtagagggcg ccggtggggc ctcccccact ctcggctgcg ctcgagcggg aggtaccccc
    13021 atcaccgaag cgttcgcgag ccgcgtccgc gtcacggcag accagggcga ccgcgcggga
    13081 gcccatgtgc ttctcctcgc acacgactcg ggcgaccccg tcctccttgt actgcttgaa
    13141 ggcctcggcc gggtgctcca ggtagccctc gatgtgcgag gtggccgtcg gggccatggt
    13201 cggcggcagg tacggcagca ggcgcgggtc gaccgcgaag cggctcatga cctccagggc
    13261 ggcggccgcg ttctcctcgc ggaccgacac ccggcccgcg tgccgcgtct cgacgacccg
    13321 gcggccgtgc acgtccgcca ggtccagcgg ccggccctcg tgcccgccgg gcgcctcggt
    13381 ggccagcggc ttcgtcggct cgtaccagac ccgctccgcc ggtacctcga ccagctcgcg
    13441 ctccggccag cgcaacgcgg tgagcttgcc gccgaagacg gcgcccgtgt cgaggcagat
    13501 ggtgttgttc aaccacgtgg cctgcggaac cggggtgtga ccgtagacca cggccgcgcg
    13561 gccccggtag tcctccgccc acgggtagcg caccggcagg ccgaactcgt cggtctcgcc
    13621 ggtggtgtcg ccgtacaggg cgtggctgcg cacccggccg gaggtccggc cgtggtactt
    13681 ctccggcaga cccgcgtggc agacgaccag ccggccgccg tcgaggacgt agtggctgac
    13741 gaggccgtcg atgaactccc gtacctgctt cttgaactcc tcgctctcgc cctccatctg
    13801 ctcgatggtc tcggcgagtc cgtgggtgtg ctggacgttg cggcccttga ggtagcggcc
    13861 gtacttgttc tcgtggttgc cgggcacgca gagggcgtcc cccgagccga ccatggacat
    13921 cacgcggcgc agcacgcccg ggctgtcggg gccccggtcg acgaggtcgc cgacgaagac
    13981 ggccgtacgg ccctccgggt gcgtgccgtc gacgtagccc aacttgccga gcagggactc
    14041 cagttcgctc gcgcagccat ggatgtcgcc gatgatgtcg aacgggccgg tgaggtgggt
    14101 caggtcgttg aagcgcttct cggtgacgat cgtggcgttc tcgacgtcct cgacgccccg
    14161 caggatgtgc accttgcgga agccctcgcg ctccaagtgc cgtagggaac ggcggagttc
    14221 gcgggtgtgg cgctggatca cacggcgcgg catgtcggcg cggtcggtgc ggcccgcgtt
    14281 gcgctcggcg cacacctcct ccggtacgtc gagcacgatg gcgatcggca gcacgtcgtg
    14341 ctgcctggcg agttcgatga gctgcttgcg ggactcctgc tgcacgctgg tcgcgtcgac
    14401 gacggtgcgg cggccggcgg cgaggcgctt gcccgcgatg tagtgcagga cgtcgaaggc
    14461 gtccttcgtg gcgctctggt cgttctcgtc gtcggagacc aggcctcggc agaagtcgga
    14521 ggagatgatc tcggtgggct tgaagtgccg tcgggcgaag gtggacttgc cggagccgga
    14581 ggcgccgatc agcaccacga gggagaggtc ggtgacgggc agggtgcgcc ccttgatggt
    14641 ctcgctcatg ccgccttcgc ctccttctcg tcggtgccgc gctgcttgaa cacggccatc
    14701 tgggtgggcg gtcccacctc cgggtcgtcg ggtccgatcg gcacgaactc gacctcgtag
    14761 ccgtgccgtt cggccacggt ggccgcccac gtccggaact cctcgcgggt ccactcgaag
    14821 cggtggtcgc cgtgccggac atgcccggcg gggagggtct cccagcggac gttgtactcg
    14881 acgttcgggg tcgtcacgag gacggtgcgg gggcgggccg agccgaacac cgcgtactcc
    14941 agggcgggca gccggggcag gtcgacgtgc tcgatcacct cggagagcac ggcggcgtcg
    15001 tagcccttga gccggttgtc ggtgtaggcg agggagctct ggaacagctg gacgcgggag
    15061 gcctggcgct cgcccatgcg gtcgagcttg agtcgtcggg aggcgatggt gagggcgcgc
    15121 atcgacacgt cggtgccgac gatctcggtg aagcgcacgt ccttgagcaa cgcctgcacc
    15181 aactggccct ggccacagcc gagatcgagc acgcgagccg ctcccgactc cttgagcgcg
    15241 gcgatgatcg cgtcccggcg ccgcacgacg agcggtgtcg gcttctcctc ggtttcgccg
    15301 tccaccgcct gctcgaccgc gtcgtccacg gtctcctcga cctcgccctc ctcgaccgcg
    15361 ttgtcgatct cctcgacctc gctgtcgtcg gcctcggcca gccgcacgag ttccaaccgc
    15421 tccatggcct gccgggtcag cgaccagcgg cgggacaggt aacggctggt gatcagcttg
    15481 tgctccgggt ggtccgggag ccagccctcg cccgcccgca gcagcttgtc gacctcgtcg
    15541 gacgacaccc agtagtgctt ggcgtcgtcg aggaccggca gcagcacata caggtggcgc
    15601 agcgcctcgg cgagggtcag cgactccgac tccaggacga gccgtacgta acgggaggcg
    15661 ccccactccg ggaacgcggt gtccagcgcc accgcctcgg ccgtgaccgt ccagccgagc
    15721 ggctcgaaga gcttgacgac gaggtccggg ccgccgcgcg cgggcagcgc cggtatctcg
    15781 acgcgcagcg ggcgggtctg ctccgggagt tcgggacggg ccttgcagtg gccgcgcacg
    15841 gcgctggaga agacgtcgtt cagcgcgacg gcgaggaggg aggaggccgc gtacgggcgg
    15901 tcgttgacgt actgggcgag cgccgcgtcg ggtgcgccgc cacggccctt gcccttgccg
    15961 cgccggacca gcgccaccgc gtccacctcc agcaacagcg cggccgtgca ccgctcggcg
    16021 tccgcctccg ggtagaggac gtgcgccttg ccgtaggagg tggagaacgc ctgcgtcttg
    16081 tcgggatgct tgtgcagcag gaagccgagg tcggtcgcgg ggcgctctgg ggtaccggtg
    16141 gtactgatcg tcaggaacac ggtgggtgcc tcgtagtggg tgtctgagct gcggagaccc
    16201 caacgtacag ggaagggggc gggcgcactc ggggatttgc gcccgccccc tcacgtgacc
    16261 gtcagggcag ttcggtcacc cggtccgtcc ccggtggtgc caccgggctg tgagcggtga
    16321 ggtagtcggt cagcgcggtg atgtcgtcgc cgcctccgac cgtgttcccg ccctcggcga
    16381 aggtggtgaa gccgtcgccg cccgccgcga ggaaggtgtt ggcggtcacg cggtacgtgg
    16441 tgtcgggctt cagcggttca ccgttcagct tgatcgatga cgggtcgatg cggtcgccga
    16501 ccggggcgct gcgggagaag gagtaggtca ggcccttgga gacgcccagc atcagggtgg
    16561 gtgcgcgggt gccggagtcg ttgaactgtt cctccaggat cttctcgatc cgtgctccgg
    16621 tgaggtcgac cgacaccagg gacccggcga agggctgtac ggcgaaggcc tcggcgtagg
    16681 tgatctcgcc cggcgcctcg ccgcccgtcg aggaggcgtg gacgaggtcc gcccgtacgc
    16741 cgccggggtt catcaacgcg atctgggcgc cgcctcgttc gggtgccgag gtggcggcca
    16801 gctgggcgtc ggcgacgagg ttcgcgaggt ccgactcggc gtcgcgggtc tcggagcggg
    16861 tgatgtcggc ggtgacgctg ccgacgacgc ggttggcgag gggcgcggag agcgccttcc
    16921 acttgtcgat gacggccgtc tggtcggcgt ccttggtgac ggtgcgggtg acgaggtggt
    16981 tcatcgcggc gacctggtcg cgtacgacgt cgccggtacg gcggtccacc gggaggcgcg
    17041 tctcggtgac gacgcggccg aaggacgagg ccgaggtgac cgagcggggg ttgccggccg
    17101 ggtcgggcag ggagcagatg tacggctggt gggtgtggcc ggtgacgacg gcgtcgatgg
    17161 ccgggtccag gtgcttcgcg atgtcgacga tggggccgga gatgccgtcg cactgcccgt
    17221 acgagcctgc ctgcacaccg ccctcgtgga gcaggaccac gatcgcctcg acgccctgcc
    17281 ggcggagctt gcgggcggcg gcgtcggcgg tctcgacctc gtcggtgaag cgcacggatt
    17341 tgatgccgga ctggccggtg acctcggggg tgccctccag ggtcatgccg atgaagccga
    17401 cctcgacgcc gtcgaccttc ttgacccagg tgggggcgag gagcggctcg ccggtggtgc
    17461 ggtcgaggac gttggccgcg agccacggga aggcggagcc gtcgtacggc tcgtcctcga
    17521 ggtagcagcc gtcctcgggg tggcagccgc cgtgctggat gcgcagcagt tcctcggtgc
    17581 cctcgtcgaa ttcgtggttg ccgacgctgg tgacgtccag gtgcagtttc tccatggact
    17641 cgacggtcgg ttcgtcgtgg aagaggccgg agaggaaggg gctggcgcct atgacgtcac
    17701 cggcggcgac ggtcagcgag gcgtccgtgc ccgcgcggag ctgcttcagc cgggccgcca
    17761 gatactcggc gccgccgacc ggcgtggact tcgcgtccag cttggagccg aggttggcgt
    17821 cacggcccgt gggcggctcc aggttgccgt ggaagtcgtt gaaggagagc agttggacgt
    17881 cgacggtgga cggctgcttc ggggtgacgg ggaaagcgcc ggtcaggacg ccggggcgca
    17941 cggacagcag atggaacttg gtgacgctgc cgttgaagcc gaagttgtcg tcggcgacga
    18001 ggacgagggt gcgggagccg tcgggcaggg tcgggcccca ggtgatgccc tcgacgttgt
    18061 cggcgtccgt gccggagagg gtgaagtcgt agagcagctt cttcggcatg ggcctctcgg
    18121 agccggacag cctgtcctcg ccgtgtacgt ccgtcgcgcc tcgggtggtg gtccagtaca
    18181 ggcggatcgc gaaaccgaca ccggaggcga aggagcgctc gacggtgagg tagtcggtct
    18241 tgttgatcgc gaggatctcg gagacgcccc ggtccgccgc gtacgtgccg acgggggcgg
    18301 gcagcggggc ggtgggcgcg gcggagatcg ggtcgacctc gtagacgtgc tccgcctccg
    18361 cctcgccggt acggcggtcc gtcaccagca gccgggacgg gctcttggcg gtcagtccgg
    18421 ccgccgggcc gtcctggacg agcgcgttct cggtgatcgt gacgacctcg cgcccgtccg
    18481 gggtgagggt cagcccctcc agggcctggt tgttgcggac cccggcggtg agtgtgcccg
    18541 actccgagcg gaccggggcg tacgccttcg gcagcggcag gtcgcgtagg tgcgcaccgg
    18601 acgcggacgt ctcacggacg aacgccggct gcccggaggc cgaggcgccc tcactggtcc
    18661 acagcagacc cttgccgtcc gggttccagc ggatcgcctc cgggtcgacg gccttcgggg
    18721 cgaagggttc gccggtcctg tcgtcgagga cggtcagggc gtcgagggca ggcttgtcct
    18781 cggcgaactc cttgtcctcg agcggcagtc ggagcgagta gaagcgggcc ttgccgttct
    18841 ccgagcggtc gtcgctgagg gcggcgtagg tgtgggtctt cgggtcgtag tcgataccgg
    18901 agaggccgcc gaagggcatg ccgagttcgg tggttccggc ggggacggtg agggtgtcga
    18961 ggagggtgat gccgttctgg gtcttcttcg gggcgctgtc cgcttcgggg gccgcgtcgg
    19021 ccgcgaagcc gccggcgaag gcgacgccgc cgaggagggc ggaggcggtg aggccggcga
    19081 gcgccacgtg tctgcggcgg actcgccgtc ggtgtcgggg catgggtggg tgtcccttcc
    19141 gggagagggt gagggtgggt ttccgggcag gccggaggaa cggagggtcc taagggacgt
    19201 tggacctcgc ggagagggag ctcagaggga ggccggggcc acctccccca cgcctcgccg
    19261 cttcctgcgc cacgcgtaca gcgcgagggc gaggagcgtc atggcgtacg ggatggtcga
    19321 gaccagctgc ggtggtacgt cgagggtgcc gagctgtacc gccagggcct cggcggcgcc
    19381 gaaaccgagg gcggcgagga agacgcccca gggacgcagg ccgccgagga acaccgcggc
    19441 gagggcgatg aagccgcggc cggcggtcat gtcccggacg aagaaggaca cgtaccccat
    19501 gctgaggaag accccggcga gcccggcgag cgcgccgctg agggcgagcc cggcgtactg
    19561 gacgcgccgt accgcgatgc cgaccgaggc ggcggcgtcc ggcatctcgc cgaccgcgcg
    19621 gaggtggaag ccgaagcggg tgcggaagaa gagccaggcc acgaaggggg cggcgaggaa
    19681 ggccagccag gtgaccaggt tctggccgct cagcacctcg cccaccaccg ggatgtgctc
    19741 gatgccgggc agggtgaccg tcggcagggt gccgctcttg aggcctgagg tgccgccctt
    19801 gtcgtcgagg agggtgaaga cggcgtaggc ggtgccgccg gaggcgagca ggttgaggcc
    19861 gatgccggcg atgatcgcgt cggcgcccaa ttccaggcgg agcgcggcga gcagcacacc
    19921 gaggaggacg gccacggcta ccccggccag ggctccggcg gcgaccgatc cgctgtagcc
    19981 ggcgaccagc gcgcccgtgc aggcggcgct cagcatctgg ccctccaggg cgatgttgct
    20041 gatgccggcg cgttcggcga cgagtccgcc catggcggcg agcagatagg gggtcgcgac
    20101 gcgcagcacg gccgcgagga aggcgctgct gaggacgacg tcgaggacgg agttcatcgg
    20161 gcacccgcct caccgattgc ggtggcctgt ctgcgggcga ggcggcgctt gaggaggtcc
    20221 gggagggcct gggcggtgac cagcagcacg atgaccgcct ggatcacgac cacgatctcc
    20281 gtgcccacgt ccgtctgctg ttccatgatg tctcccccgg cacgcaggta ggagtagaag
    20341 aggccggcga ccacgacgac cagcgggttg ttgcgggcga gcagcgccac cacgatcccc
    20401 tcgaaggcga ggctgccggc gagcccgggc tccagacgtc cgtacacgcc ctgcacgaga
    20461 tgcgctcccg ccaggcccgc gacggccccg ccgatcacga agctccactc gatggcgcgg
    20521 ggcacccgga taccgccgta ctcggcgaag tgcgggttgg aaccggtcat ccggatgcgg
    20581 tagccgagcg gggtgcgggt gatgagcagc cacagcgcga cggcggtgag cagcatgagg
    20641 aggaagccga cgttggcgcg gccgaagggg atgccgagcc agtcggtgag cggggtgagg
    20701 gcggagtccg gctggatgcg ctccgagtgg acggcgctgc tgcccggctc cttcagcggg
    20761 ccgttgacca ggtagtcgta gacgcggacc acgatggcgt tgagcatcag cgtcgccacg
    20821 atctcgttgg cgccgagccg ggccttcatc gatcccggta cgaagcccat gccggcgccc
    20881 gcagtcgccg cggcgaccag gggcacgatc acggcggcga ccggcggcag cggcaggaag
    20941 acggccaccg tggccgccgc caacgcgccc gcgtacagct ggctctcggc gcccaggctg
    21001 atctgccggg cccggaaggg aatcgccacc gacaggccga gcagggtgag tgtggtggcg
    21061 tcctccagcc agcggccgac gcggaaggaa cgctccaacg ggccggtgag cagggcctcg
    21121 tacgccgcga tcgggtcctt gccggtggcg agcatcacga ggaagccgat gacgagggcg
    21181 gccaggatcg tcgccagggt catgctgaga tcgacggcga ggccgcggcg ccgggtggcc
    21241 ttgtactccc ggcggtcctc gctctcgatg agcgtggtcg gagggctggt ggtcattcgg
    21301 cggccgcctt cccggagtcg ccggaaccgt cgtcgtccgg gtcggtcgtg gggccggtgt
    21361 cggcgtgggg gccggtatcg gcgcgcgggc cgttatcggc gtgggttccg ggcgcggagt
    21421 cggaaccggc cgtgccgtcc aacccggccg tcaggtggtt cccttcgtgg tgttcgaccc
    21481 cgagcatgta cagcccgacc cgcttctccg tgaggccggt cgtgtcgtcg aagcggccca
    21541 cgaggcggcc gtccttcagg acgagcaacc ggtccgagag ggcgaggagt tcggtgaggt
    21601 cggcggagat gaggaggacg gcggcgccgt cgtcccgggc ggcgacgaga cgttcgtaca
    21661 tgaagcgcat ggcgccgatg tccacgccac gggtgatctg ggaggcgatc aacagccttg
    21721 gtccggcgga gagttcgcgg gcgacgacga ccttctgcat gttgccgccg gacagcgcgc
    21781 gcaccgggac ggacgggtcg ggggtgcgga tcgcgtagtc ctcgacgagt tgc
//
