LOCUS       NZ_CP102512            22208 bp    DNA     linear   CON 11-FEB-2024
DEFINITION  Streptomyces sp. CA-210063 chromosome, complete genome.
ACCESSION   NZ_CP102512
VERSION     NZ_CP102512.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CA-210063
  ORGANISM  Streptomyces sp. CA-210063
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10859970)
  AUTHORS   Nielsen,J.B., Gren,T., Mohite,O.S., Jorgensen,T.S., Klitgaard,A.K.,
            Mourched,A.S., Blin,K., Oves-Costales,D., Genilloud,O., Larsen,T.O.,
            Tanner,D., Weber,T., Gotfredsen,C.H. and Charusanti,P.
  TITLE     Identification of the Biosynthetic Gene Cluster for Pyracrimycin A,
            an Antibiotic Produced by Streptomyces sp
  JOURNAL   ACS Chem Biol 17 (9), 2411-2417 (2022)
   PUBMED   36040247
REFERENCE   2  (bases 1 to 10859970)
  AUTHORS   Joergensen,T.S., Gren,T., Blin,K. and Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2022) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 05-AUG-2022
            Assembly Method :: Flye v. 2.9-b1768; Polypolish v. 0.5.0; POLCA
            polisher from MaSuRCA v. 4.0.5
            Assembly Name                     :: M642_aaa1.6.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 55.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 11:12:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,501
            CDSs (total)                      :: 9,410
            Genes (coding)                    :: 9,051
            CDSs (with protein)               :: 9,051
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 359
            CDSs (without protein)            :: 359
            Pseudo Genes (ambiguous residues) :: 0 of 359
            Pseudo Genes (frameshifted)       :: 141 of 359
            Pseudo Genes (incomplete)         :: 302 of 359
            Pseudo Genes (internal stop)      :: 23 of 359
            Pseudo Genes (multiple problems)  :: 101 of 359
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:19:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2215944
            Orig. end                         :: 2238152
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102512.1.
            Bacteria and source DNA available from Tilmann Weber, Dr.
            Professor, Novo Nordisk Foundation Center for Biosustainability,
            Kemitorvet, 220, 327D 2800 Kgs. Lyngby, Denmark.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22208
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="10"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22208
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22208
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12208](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12208)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    305..319
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     gene            566..1819
                     /locus_tag="JIX56_RS09555"
                     /old_locus_tag="JIX56_09555"
     CDS             566..1819
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308299.1"
                     /locus_tag="JIX56_RS09555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09555"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_257550797.1"
                     /transl_table=11
                     /translation="MGLLLELGYPTVAELESAARALTVRRPGLCALRRIGVSRAGRPLR
                     LLSVGHARHAVLVVAGAHANEPTGGSTVLALAERVLRERALRTGVSWHFVLCADPDGAS
                     LHMAQAPRTLLDYHLGFFRPAGPEQPEWSPSVLPPDRLPPETRALLKVINELRPYLQVT
                     LHGTDLGGSWVQLTKDVPGLAEPFAKSAAELGIPVEMGASDAAGWPVSGPGVFVMPRPG
                     GHAAYPSMPDDARHSTWYQAHRYGGLTAVVEVPMWASDLVDDTAPHPAPAAALRHLARR
                     LLAEAGQVERVLADALPRLPGPEGPLLRAARWALALVPGLARDWADGPPPDLSTAYVGS
                     VDAFGRRLPLRAGAMLLRVLREADDPAAPYLEGVVSDWCESFADRFRARWVPICDQVEH
                     QVRTVLAAALYARGDVGS"
     gene            complement(1914..2321)
                     /locus_tag="JIX56_RS09560"
                     /old_locus_tag="JIX56_09560"
     CDS             complement(1914..2321)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481981.1"
                     /locus_tag="JIX56_RS09560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09560"
                     /product="subtilase-type protease inhibitor"
                     /protein_id="WP_257538715.1"
                     /transl_table=11
                     /translation="MTNTTHAVRSGLFAALALLTVGASAPDRTSAAHSDWLYVSLTRGD
                     ARSFDTRGTLLLCDPPQGHGRAAQACAQLRETGGDITRIPHEHAICAQIYAPVRATAQG
                     RWNGRPITYEQTFANGCVMTARTGAVFALSD"
     gene            complement(2318..3682)
                     /locus_tag="JIX56_RS09565"
                     /old_locus_tag="JIX56_09565"
     CDS             complement(2318..3682)
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062765.1"
                     /locus_tag="JIX56_RS09565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09565"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_257538717.1"
                     /transl_table=11
                     /translation="MDELSARAAALVARHPHRARLRRVGTSRAGTPMWLLSVGRGSRHT
                     LIVAGPHANEPVGGATVLRLAERALADPRLSDQADTTWNLLLSLDPDGSRRNEGWLSGP
                     YTLGHYFRHFFRPGFLEQPEWLPDGAAGAVLPETRALLDLQDELRPFLQCSLHGVDVGG
                     GFVELTRELPGIAQRVARTAARLGIPRELSPYDTLYWPRLGPAVYRIPPPRRGDLAAAI
                     TEAAVESTWYHPHRYGTVTAVVEAPMWGVTAVEDASPSPDADAVLRTVSRALRRDTRLL
                     ESILARVRPSAGAGPDAARLLAPVDDYVLVGPGLADSWDPDVHDVAARPLPPLDTARLT
                     TLALSGRRVALRTAGLLHQLVTRAGHDPADALPELDRLIDEWCADYRDGYGARWIPVAR
                     QAEYQARVVLAAFELTAGRPRPESAPPPPCPDAHADSRSGEPPWSSEPAVPMHRE"
     gene            complement(3876..4427)
                     /locus_tag="JIX56_RS09570"
                     /old_locus_tag="JIX56_09570"
     CDS             complement(3876..4427)
                     /GO_function="GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481978.1"
                     /locus_tag="JIX56_RS09570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09570"
                     /product="DUF1707 and FHA domain-containing protein"
                     /protein_id="WP_257538719.1"
                     /transl_table=11
                     /translation="MTSSFEFPTHPARLSDAERDRALRVLRDGVALGRLSHDTFIRRME
                     LALTARRSDELAALTADLPAEKRWSRLVLGTVGAISGFGVKLRRAWQAERLPKLQLPHP
                     ASGHGLRIGRDPASGLRLSHETVSRVHAELTRQGGMWILRDLGSTNGTTVNGRRVIGAA
                     VVKDGDQVSFGRMTFRLSSE"
     misc_feature    4655..4669
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.54"
                     /tool="antismash"
     gene            4669..6414
                     /gene="treZ"
                     /locus_tag="JIX56_RS09575"
                     /old_locus_tag="JIX56_09575"
     CDS             4669..6414
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133692.1"
                     /locus_tag="JIX56_RS09575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09575"
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_257538730.1"
                     /sec_met_domain="CBM_48 (E-value: 0.00017, bitscore: 20.8,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 5.4e-12, bitscore:
                     45.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFEVWAPQADRLTLHCAGATHVMERDPERPGWWTAEAEASDGTR
                     YGFAVDDGPVRPDPRSRRQPDGPDGLSAVVDHGRYAWRAPWSGRGLPGAVLYELHVGTY
                     TPEGTLDAATERLGHLAELGVTHVELMPLCPFPGTHGWGYEGVSLWAVHEPYGGPEALK
                     RFVDAAHELGLGVVLDVVHNHLGPSGNYLPVFGPYFTERHHTPWGAAVNLDAPGSDDVR
                     EYFLGSALAWLRDYRLDGLRLDAVHALRDTRALHFLEELSTAVDTLADEVGRPLFLVAE
                     SDLNDPRLVTPRAQGGLGLHAQWNDDFHHTLHTTLTGESQGYYEDFARAGLAGLAKTLT
                     GGYFHDGTYSSFREHRHGRPLDRTSVSAHRLLGYTQTHDQVGNRAQGDRLSASLSPGLL
                     ACAAALVLTGPFTPMLFMGEEWAASTPWQFFTDHTDPELAQAVRRGRRREFAAHGWAEE
                     DVPDPQDPATRDRSCLDWSEPARAPHARVLAWYRDLITLRRTLPDLSDPDLSDVKVAFD
                     EEARWFGFRRGDVLVAVNLGKETAMIPVGVPDARVLAAWEPVEGPGADGVLSLGGESCV
                     VLTVA"
     gene            complement(6636..7559)
                     /locus_tag="JIX56_RS09580"
                     /old_locus_tag="JIX56_09580"
     CDS             complement(6636..7559)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481974.1"
                     /locus_tag="JIX56_RS09580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09580"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_257538732.1"
                     /sec_met_domain="APH (E-value: 1.2e-19, bitscore: 70.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPTPTADSVRRLVRSLLKNGEGRGGGPDVRPVAGDEAHRTWW
                     VGTRHVLRLTTDRHAVGRQRRELRLRDLVRPHIGVAVPVSVAAGEWSEGLTYTLDTRLP
                     GGTAEDHDVSAVGEADLAALLTGLREVPLRQVETLGVPRPAPRSLETLRTAAGRAARRL
                     AEADEFDAARLGQLTPASAAQLTAPAAVLVHHGLTGDRLVVSADGRVRGVLDWADAVIG
                     DPAEDIAGLATAVGAPAAVRAATLAGYGARPCLRGLWLARCDTLIALAEGVQGRGAAPL
                     PVLRGRLRRTWEAILLERVTDLRGED"
     gene            complement(7608..8768)
                     /locus_tag="JIX56_RS09585"
                     /old_locus_tag="JIX56_09585"
     CDS             complement(7608..8768)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983601.1"
                     /locus_tag="JIX56_RS09585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09585"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_257538734.1"
                     /transl_table=11
                     /translation="MTGTPSDGPATVTTDATPAPFTTDDYRARMRRAARAAADAGLDGL
                     LVAPGPDLVWLTGHRPPETERFTMLVLRDGEDPVLVVPTLEAPDAAEAPGGPALTLRDW
                     TDAKDPYEAAVSLLGPRGRFGVSDNTWALHLLGLRRRLPETTYVALTEGLPMLRAVKDT
                     AELERMAAAGAAADRAYEEIRQVPFAGRREKEVAADLAGLLRRFGHSQVDFTIVASGPN
                     GANPHHEAGDRVIGRGDMVVLDFGGLKDGYGSDTSRTVHVGEPAAEEREVHDIVRAAQE
                     AGFRAVRPGAACQDVDRAARAVITEAGYGDRFIHRTGHGIGVTTHEPPYMVEGEERPLV
                     PGMCFSVEPGIYLPGRFGVRIEDIVTVTEDGGRRLNNTPREMATVE"
     gene            9123..9878
                     /locus_tag="JIX56_RS09590"
                     /old_locus_tag="JIX56_09590"
     CDS             9123..9878
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308343.1"
                     /locus_tag="JIX56_RS09590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09590"
                     /product="phosphodiesterase"
                     /protein_id="WP_257538736.1"
                     /sec_met_domain="Metallophos_2 (E-value: 1.3e-07, bitscore:
                     30.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVLAHISDLHLDGSERATRRAERVRDLLWGLPGRVDALLVTGDI
                     ADHGTEAEYEEAASILGLREGGAPFPVLTCPGNHDSRAPYRKALLGEPAADGPVNSVRV
                     FADAAVLMCDSSIPGQDEGELDAQTYAWIEETLDELDGERPVLLAFHHPPVALHHPLPD
                     AYRLGRPAALARLLGRRPEIAGLVTGHAHTPAATTFAGRPLVVGPGVTWTLRLPWEGDQ
                     AADREAPPGLAFHVLDDEGRLTSHFRVAS"
     gene            complement(10001..12208)
                     /gene="cyc2"
                     /locus_tag="JIX56_RS09595"
                     /old_locus_tag="JIX56_09595"
     CDS             complement(10001..12208)
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481971.1"
                     /locus_tag="JIX56_RS09595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09595"
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_257538737.1"
                     /sec_met_domain="T1TS (E-value: 6.7e-79, bitscore: 265.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFELPHFYMPYPARLNPHLEEARAHSTGWAREMGMLEGSGVW
                     DQKDLEAHDYGLLCAYTHPDCDGPALSLITDWYVWVFFFDDHFLELFKRSQDRAGGKAH
                     LDRLPLFMPLDLSTPVPEPRNPVEAGLADLWARTVPSMSMDWRRRFAVATEHLLNESMW
                     ELSNINEGRIANPVEYIEMRRKVGGAPWSAGLVEYATAEVPAPVAESRPLRVLMETFSD
                     AVHLRNDLFSYQREVEDEGENSNGVLVLETFFGCGTQQAAETVNDILTSRLHQFENTAL
                     TEVPALALEKGLTPDEVAAVAAYTKGLQDWQSGGHEWHMRSSRYMNEGAASSRGPLDFG
                     GAVLSGPALVTRPGFGTAAANVGALLATAAAERLRAHTHVPYQKVGPSRLPDFYMPFEV
                     ELCPHLDAARPRLTTWMHAMGMLSEGVWDEERLAAADLPLCAAGLDPDATPEQLDLSSQ
                     WLAWGTYGDDYYPLVFGHRRDLAAARLTTARLSDCMPVEGEAVTVPVNGMERGLIDLWA
                     RTTAGMTPDQRRGLKASVDKMTESWVWELFNQIQNRVPDPVDYLEMRRATFGSDLTLSL
                     CRMGHGPQIPDAVYRSGPVRSLENAAIDYACLINDVFSYQKEIEYEGEVHNAILVVQNF
                     FGCDYPTALGVVHDLMTQRMRQFEHVVAHELPVVYDDFELSEEARAIMDGYVTDLRNWL
                     SGILNWHRQVDRYKPEFLARRAHGFVPDRPPVLSFAPAHAG"
     gene            complement(12384..13559)
                     /locus_tag="JIX56_RS09600"
                     /old_locus_tag="JIX56_09600"
     CDS             complement(12384..13559)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481970.1"
                     /locus_tag="JIX56_RS09600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09600"
                     /product="damage-control phosphatase ARMT1 family protein"
                     /protein_id="WP_257538748.1"
                     /transl_table=11
                     /translation="MPDTAPVIRCDDPTSFPHSVLAERHPALIRKVQDATPYGPEQRRA
                     LDELLKNTLHGTVEPPADDDWWDTWNVRRHAGRSWFSLPFLVAESCFYRQLLRAVGHFG
                     PGPWQGTDPFRPFKLAELDTPEAAAELTALGTLAQHPLPDQLKALLHGSLWGNRADLGF
                     RIQTAEEDATAADSQLVADDSESLMSLLTGAGRGAGAGAGARTLCLVADNAGRELIPDL
                     LLIDHLLTHGHFDRAVLHLKPYPYFVSDATTADTLDAVRHLVAAKTDAGHRLWSALSDG
                     RIVLRAHPFSCAPLPYADMPADLRDDFASADLTLLKGDLNYRRLVGDRLWPPTTPFAEV
                     TAYFPGPVAALRTLKSDVIVGLTAQKEAALVAAEGQRWRTSGTRALIQVRV"
     gene            complement(13552..14154)
                     /locus_tag="JIX56_RS09605"
                     /old_locus_tag="JIX56_09605"
     CDS             complement(13552..14154)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009325129.1"
                     /locus_tag="JIX56_RS09605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09605"
                     /product="hypothetical protein"
                     /protein_id="WP_257538750.1"
                     /transl_table=11
                     /translation="MSTEKTETYGRPEGQPVAAVCPGCGGTGPAVRTVADACADPESRR
                     GGLTDRLARSPGVHDGSDSLVHFLEGMVMAGIGAGLAYSGVQNDKPLYTIGGSLLAVLL
                     FVGTIVVVRGERRERKAVVAGEAHAERLWRPAHHCSSCGSVFYPGGSPWPGPLTPEQFK
                     KYVWTEAGYGKQLDTKVKGVSLPPGMPSGPGGTPGHA"
     misc_feature    complement(14171..14186)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.96"
                     /tool="antismash"
     gene            complement(14290..16107)
                     /locus_tag="JIX56_RS09610"
                     /old_locus_tag="JIX56_09610"
     CDS             complement(14290..16107)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481968.1"
                     /locus_tag="JIX56_RS09610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09610"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_257538752.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 9.3e-51, bitscore:
                     171.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTSPSRTAGRKLISVAAVSVALVAGMTSSVAVAAPSAKADAAPA
                     VAGATEAAPGTTAERLIVGYKSGAAEAKSNKAADADAVAKGKEAGESLDFQRRLGSGAA
                     LVDLGEDLTKTDVADVIAEYQADPQVAYVVPDRLNKPLATPNDTEYSKQWDLYESTAGM
                     NVPGAWDTVTGSGVTVAVIDTGYVAHSDLAANIVGGYDFIADTAVANDGNGRDSNPADP
                     GDWTSDGECATDWTATTSSWHGTHVAGTIAAVTNNSKGVAGIAYGAKVSPLRVLGKCGG
                     YDSDIIDAITWASGGTVSGVPANTNVAKVINMSLGGSGACTTATQTAINSAVNRGTTVV
                     VAAGNSNANAANYSPASCANVISVAATNRAGSRSYYSNFGSVVDIAAPGGDTRTTASGG
                     ILSTLNTGASGPGSETYDYYQGTSMAAPHIAGLAALLKSASSALTPAQIESAIKTNSRA
                     LPGTCSGGCGAGLADAAKTVQAVTGGSGGGSTGGTTFTNATAVSIPDNGAAIESSISVS
                     GRTGNAPSTLQVGVDITHTYRGDLVLDLVAPDGSTYRLKASSSDSADNLVTTYSVNASS
                     EVANGTWKLRVQDVASADTGRLNSWKLTF"
     misc_feature    complement(16154..16168)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.33"
                     /tool="antismash"
     gene            16509..17564
                     /locus_tag="JIX56_RS09615"
                     /old_locus_tag="JIX56_09615"
     CDS             16509..17564
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114198.1"
                     /locus_tag="JIX56_RS09615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09615"
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_257538754.1"
                     /transl_table=11
                     /translation="MYRLSARRTTGRGTTGRRTACRTAACRTTGHRTAVTAAAVTVVAP
                     LILTAGAVTPAWAHGAPTDPVSRVSACSPEGGSQGSAACEAAVAANGAPFTAWDNMRIA
                     GVNGRDREVVPDGQLCSGGLADYRGLDLARADWPSTRLSPGTTLNLTYRSTIPHTGTFK
                     LFLTKPGYDPTEPLKWSDLPGKPFASITDPPLKNGSYQFSAKLPADRAGHHVLYTIWQN
                     TSTVDTYYSCSDVVFPKAKQANSEAGDGSSAKTPAGSEETASEKPAAEKSEPATTAPTE
                     STQAPPAEAADNADDDAQAADPGSPVASTTDESGAPVPLVAGGATALALVLAVGTALFL
                     RGRGRRSRISD"
     gene            complement(17695..18348)
                     /locus_tag="JIX56_RS09620"
                     /old_locus_tag="JIX56_09620"
     CDS             complement(17695..18348)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999857.1"
                     /locus_tag="JIX56_RS09620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09620"
                     /product="Tat pathway signal sequence domain protein"
                     /protein_id="WP_257538756.1"
                     /transl_table=11
                     /translation="MRTRSLLALAATTAALMVSAVSPASAADTVLTTGGLAGDAVAVGD
                     VLNASLASGTTGKFYSSATGTSGVSCAESTFTATVTDNPAAPGTATERVDAHTFGSCTS
                     NVVGVLGVTGVTVNNLPYTTTVTSDGVVTVSPAAGSVLQTTVVLRTLLGTINCVYQAAS
                     ITGTSSNDDNSINFTSQPFTKTSGSSLCFATGYFTAKYAPVTDATQGGATVYTN"
     gene            19102..19764
                     /locus_tag="JIX56_RS09625"
                     /old_locus_tag="JIX56_09625"
     CDS             19102..19764
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999858.1"
                     /locus_tag="JIX56_RS09625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09625"
                     /product="DUF6230 family protein"
                     /protein_id="WP_257538758.1"
                     /transl_table=11
                     /translation="MASSSDAAASTNERPEGPEASGRRGRVRLKRAAVMAVPATAVAAG
                     LMILTAQGALGVQFAISGMPFVVTADKLEGEGFAQFGSLDHMIENSPNEGDTGGQVLVV
                     TSVVKNGKLTNLCQSVDLGGIQLVLSAGNKGTPVSVKNLAIDSDDISGDASFNNIEIGR
                     DSSTFDKVDQQGPRGVYGQQADSVVITDLYQHNYAATAAVFKLPDLHMSFTSEGCPQ"
     gene            19761..20165
                     /locus_tag="JIX56_RS09630"
                     /old_locus_tag="JIX56_09630"
     CDS             19761..20165
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034198.1"
                     /locus_tag="JIX56_RS09630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09630"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_257538760.1"
                     /transl_table=11
                     /translation="MSRFREWRGHRPFAGGLLLVLGGAEILVTMKAPLPVILKIGMQGL
                     AGYLLPSLMIVCGSLIIFNPAQRLFYSILGIMLSLGTWLTSNIGGFVVGLLLGAIGSTL
                     AFGWLPDQEPRRKRSAKPKGQPEQHAAELG"
     gene            complement(20276..20665)
                     /locus_tag="JIX56_RS09635"
                     /old_locus_tag="JIX56_09635"
     CDS             complement(20276..20665)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999860.1"
                     /locus_tag="JIX56_RS09635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09635"
                     /product="hypothetical protein"
                     /protein_id="WP_257538762.1"
                     /transl_table=11
                     /translation="MTVSRAPRWMCSYSPEVRTVPAGRWWNAIRVPVALGTLALKSLGD
                     ESGAVIKDGYGGIMYWLVPPGDASEWRMADVQVLGRGSHVAVPPLRRTSGPGLYWRVPL
                     SHDRYWTDTERLRSALSEAAVTAAL"
     gene            20869..22116
                     /locus_tag="JIX56_RS09640"
                     /old_locus_tag="JIX56_09640"
     CDS             20869..22116
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009325460.1"
                     /locus_tag="JIX56_RS09640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09640"
                     /product="cytochrome P450"
                     /protein_id="WP_257538764.1"
                     /sec_met_domain="p450 (E-value: 1.8e-19, bitscore: 68.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGHPSPLVIDATGRDIHGEAARIRETGPATRVVLPGPHDVEAWAV
                     SSPDLLKRLLTDPRVSKDPRQHWPRFAAGEITPEWPLFTWVAVQNMFTAYGGDHKRLRI
                     LVSKAFTARRTAALQPRVEEITKELLDRVEEGFRRGVTVDLRQEFCYPLPIQVISELFG
                     LPEERGLVLKELVDKLFDTSAAPGEMNAAYERMYGVLGELVSAKRESPGDDLTSGLIAA
                     RDEDDTRLSEQELLDTLVLMVSAGHETTVNLLDQAVHSLLTHPEQLAHVREGRATWDDV
                     IEETLRVQAPVASLPLRYAVEDLDLAEFGGPEGVVIAKGDPILAAYAAAGRDPERHGKD
                     ADVFDVTRADKEHLAFGHGVHYCLGAPLGRMEARIALPALFERFPVLELGAAEEELGHV
                     ESFISNGHRRLPVRKA"
ORIGIN
        1 cggaggagga gtaccgggcg ctggtggacc cggacaaccg gcggcccttg gcgcccgggg
       61 agggggcttc cgacaagttc cggctcacct cggccgcgct acggctgcgc cggcggcggc
      121 cggaagtgtt cggggacggg gcgacgtacg cgccgctgcc ggcggacgga ccgggggccg
      181 ggcactgtgt ggcgttcgaa cggtccggtg cggtggtcac cgctgtcacg cggttgtcgc
      241 tgcgactggc ggaggccggc ggctgggggg acacgcggct ggcgctgccg gaggggcggt
      301 ggaccgatgc gctcggccag gagcgggagt tcgcggggga cgtgcgggtg gcggagctct
      361 tcgagacgct gccggtcgcg ctccttgaac gggtcgacag gcagccgtga ctcctgcgcc
      421 gggtagcggt aactcccgtg ccgggtaacg gtgaatgcct ctgggcgccc cttggagccg
      481 ccccttccac ggaaggacac tggacatatc ccccactcga ttcggtcggg tggagggatt
      541 gtgatgccag gtggactgga cgggggtggg tctcctgttg gagctcggtt atcccacggt
      601 ggcggaactg gagtcggcgg cgcgggctct gacggtccgt cggccggggc tgtgtgcgct
      661 gcggcggatc ggtgtctcgc gcgcgggccg gccgctgcgg ctgctgtccg tgggccatgc
      721 gagacatgcc gtcctggtcg tcgcgggcgc ccacgcgaac gagccgaccg gcggctccac
      781 cgtgctcgcg ctggccgaac gggtcctgcg ggagcgggcg ttgcggaccg gtgtctcctg
      841 gcacttcgtg ctctgcgcgg acccggacgg ggcgagcctg cacatggccc aggcgccgcg
      901 cacgctgctc gactaccacc tggggttctt ccggccggcc ggtcccgagc agccggagtg
      961 gtcgccgtcg gtgctgccgc cggaccggct gccgcccgag acgcgcgccc tgctgaaggt
     1021 gatcaacgag ctgcgaccct acctccaggt gaccctgcac ggcaccgatc tcggcggcag
     1081 ctgggtgcag ttgacgaagg acgtgccggg gctcgccgag ccgttcgcca agtccgcggc
     1141 cgagctgggc atacccgtgg agatgggcgc ctccgacgcc gccggctggc ccgtctccgg
     1201 acccggggtc ttcgtcatgc cgcggcccgg cggccatgcg gcgtacccga gcatgccgga
     1261 cgacgcccgg cacagcacct ggtaccaagc ccaccggtac ggcggcctga cggcggtcgt
     1321 cgaggtgccg atgtgggcga gcgacctggt ggacgacacg gccccgcacc cggccccggc
     1381 ggcggccctg cggcatctgg cgcggcggct cctcgcggag gcgggacagg tggaacgggt
     1441 cctcgccgac gcgctgcccc ggctgccggg gcccgagggg ccgctgctgc gtgccgcccg
     1501 gtgggcgctg gccctggtgc cggggctggc ccgggactgg gccgacggcc cgccgccgga
     1561 cctctcgacg gcgtacgtgg gcagtgtgga cgccttcggg cgccggctcc cgctgcgggc
     1621 cggggcgatg ctgctgcggg ttctgaggga ggccgacgat ccggctgcgc cgtatctcga
     1681 aggggttgtc tccgactggt gcgagtcttt tgccgaccgg tttcgtgcgc ggtgggtgcc
     1741 gatctgtgat caggtcgagc atcaggtgcg tacggtgctg gcggctgcgt tgtacgcgcg
     1801 gggggatgtg gggtcctgag tgcgcctact ggagtgcctc gtggtgtggt gaggcggctg
     1861 cgggtccgtc gtggcttgtc gcgcagttcc ccgcgcccct tacggggcgc cggtcagtct
     1921 gacagcgcga acaccgctcc cgtccgggcc gtcatcacgc agccgttcgc gaacgtctgt
     1981 tcgtaggtga tcgggcggcc gttccaccgg ccttgggcgg tggcgcggac gggggcgtag
     2041 atctgggcgc agatggcgtg ctcgtggggg atgcgggtga tgtctccgcc ggtttcgcgg
     2101 agttgcgcgc aggcctgggc ggcgcggccg tggccctggg gcgggtcgca gaggaggagg
     2161 gtgccgcggg tgtcgaagga gcgggcgtcg cctcgggtga gggagacgta gagccagtcg
     2221 ctgtgggcgg cggacgtccg gtccggggcc gaggcgccga cggtgaggag tgcgagtgcg
     2281 gcgaacaggc cgctgcgtac cgcgtgggtg gtgttcgtca ttcccggtgc atcggcacgg
     2341 cgggctcgga actccatggg ggctcacccg aacgggagtc ggcgtgggcg tccgggcagg
     2401 gcggcggcgg ggcggactcc gggcgcggac gtccggccgt cagttcgaac gcggcgagga
     2461 cgacgcgggc ctggtactcc gcctggcggg cgacggggat ccagcgcgcc ccgtagccgt
     2521 cgcggtagtc ggcgcaccac tcgtcgatga gccggtccag ctcgggcagc gcgtcggccg
     2581 ggtcgtgtcc ggcgcgggtc accagctggt gcagcagccc ggcggtgcgc agggcgaccc
     2641 ggcggccgga gagggcgagg gtcgtgagcc gggcggtgtc gagcgggggc agcggccggg
     2701 cggcgacgtc gtggacgtcg gggtcccagg agtcggcgag gcccggcccg accagtacgt
     2761 agtcgtcgac cggggcgagg agccgggcgg cgtccgggcc ggcgcccgcc gaggggcgga
     2821 cgcgggcgag gatgctctcc agcagccggg tgtcgcggcg cagggcgcgg ctgacggtgc
     2881 gcagtacggc gtcggcgtcg ggcgacggtg aggcgtcctc gacggcggtc acgccccaca
     2941 tgggtgcctc gacgacggcg gtgaccgtgc cgtagcggtg cgggtggtac caggtggact
     3001 cgacggcggc ctcggtgatg gcggcggcca ggtcgccccg gcgcggcggc gggatgcggt
     3061 agacggcggg gccgaggcgg ggccagtaca gggtgtcgta cgggctcagc tcgcgcggga
     3121 tgccgaggcg ggcggcggtg cgggcgacgc gctgggcgat gcccggcagt tcgcgggtca
     3181 gctcgacgaa gccgccgccg acgtcgacgc cgtgcagcga gcactggagg aagggccgca
     3241 gttcgtcctg gaggtcgagg agggcgcggg tctccggcag gacggccccg gcggcgccgt
     3301 cgggcagcca ctcgggctgt tccaggaagc cggggcggaa gaagtgccgg aagtagtgcc
     3361 cgagggtgta cgggccggac agccagccct cgttgcggcg ggagccgtcg gggtcgaggc
     3421 tcagcagcag gttccaggtg gtgtccgctt ggtcgctcaa ccgggggtcg gccagggccc
     3481 gttcggcgag tcggaggacc gtggcaccgc ccacgggttc gttggcgtgc gggccggcga
     3541 cgatcagggt gtggcggctg ccccgcccga cggacagcag ccacatcggc gtgcccgccc
     3601 gtgacgtgcc cacgcggcgc agtcgggcgc ggtgcggatg tcgggcgacg agtgccgcgg
     3661 cacgggcgga caactcgtcc acggtcgggt agcggaggag tggcggcagg gcacacctcc
     3721 acgcgtgtgg cgccgtcggt tcaccgggtg tgcatggtgt aagcacagtc agtcatggcc
     3781 gagaacgtac gtcaacaccc cggaagggaa ggtgagttga caaactcgct gcgtaaatac
     3841 caggccagag ctttgtgcgg ggatcggtgg ggaggtcact ccgaggagag gcggaacgtc
     3901 atccggccga aactcacctg atcgccgtcc ttcacgacgg ccgcgccgat cacccgacgg
     3961 ccgttgacgg tggtgccgtt ggtggagccg aggtcacgca ggatccacat gccgccctgt
     4021 cgggtcagct cggcgtggac gcgggagacc gtctcgtggc tgagccggag tccgctcgcc
     4081 gggtcgcggc cgatgcgcag gccgtggccg ctcgccgggt gcggcagctg gagcttgggg
     4141 agccgctcgg cctgccaggc gcggcgcagc ttcaccccga agccggagat cgcgccgacg
     4201 gtgccgagca ccagccggga ccagcgcttc tcggcgggca ggtcggcggt gagcgcggcg
     4261 agttcgtcgg agcggcgggc ggtgagggcc agctccatcc gccggatgaa cgtgtcgtgc
     4321 gacagccggc ccagcgcgac gccgtcacgg agcaccctca gcgcgcggtc gcgctcggcg
     4381 tccgacagcc gcgcggggtg cgtggggaac tcgaaagacg acgtcacgct ggtgattgtc
     4441 ggtcaggagg gccggaggtg tccagacaac ccgtaaacgg tgaccatccg cagacatgcg
     4501 ggaggacagt acgactcgcg ggttcaaaag ccccgatccg agcgcgcgcc gatctcgttt
     4561 gccgcacgat ggacggaagc ggaaacgggg cggtgtgggt gcgttcccgg aaccgcttac
     4621 cccctgacta cccaggacca cgaccggcag ccgagggaga accgttccgt gcagttcgag
     4681 gtgtgggcac cgcaggccga ccgtttgacg ctccactgcg cgggcgccac gcatgtgatg
     4741 gagcgcgatc cggagcggcc gggctggtgg accgccgagg cggaggcttc ggacggcacg
     4801 cgctacgggt tcgccgtcga cgacggaccg gtgcggcccg acccgcgctc gcgccgccag
     4861 ccggacggcc ccgacgggct gagcgcggtc gtcgaccacg ggcggtacgc gtggcgtgcg
     4921 ccatggtccg ggcgcgggct gccgggcgcg gtcctctacg agctgcacgt cggcacgtac
     4981 acccccgagg gcacgctcga cgcggccacc gagcgcctcg gccacctcgc cgaactgggc
     5041 gtcacgcacg tcgagttgat gccgctgtgc ccgttccccg gcacgcacgg ctgggggtac
     5101 gagggggtct cgctctgggc cgtgcacgag ccgtacggcg gtcccgaggc gctgaagcgg
     5161 ttcgtggacg cggcgcacga gctgggcctc ggggtcgtgc tcgacgtcgt gcacaaccat
     5221 ctgggcccct ccggcaacta tctgcccgtc ttcggcccgt acttcaccga gcggcaccac
     5281 acgccctggg gcgcggcggt caacctggac gcgcccggct cggacgacgt acgggagtac
     5341 ttcctgggca gcgcgctggc ctggctgcgc gactaccgcc tcgacgggct gcgcctggac
     5401 gcggtccacg cgctcaggga cacccgcgcc ctgcacttcc tggaggagct gtcgacggcg
     5461 gtggacacgc tcgccgacga ggtcggacgc ccgctgttcc tggtcgccga gtcggacctc
     5521 aacgacccgc gtctggtcac cccgcgcgcc cagggcggcc tcgggctgca cgcccagtgg
     5581 aacgacgact tccaccacac cctgcacacc accctgaccg gtgaatcgca gggctactac
     5641 gaggacttcg cgcgggccgg tctggcgggc ctggcgaaga ccctgacggg cggctacttc
     5701 cacgacggca cgtactcgtc gttccgggag caccgccacg gccgccccct ggaccgtacg
     5761 agcgtgtcgg cgcaccgtct gctgggctac acccagaccc atgaccaggt cggcaaccgc
     5821 gcccagggcg accgactctc cgcctccctc tcccccgggc tgctggcctg cgcggccgcg
     5881 ctggtgctga cgggcccctt cacccccatg ctcttcatgg gcgaggagtg ggccgcgtcc
     5941 acgccctggc agttcttcac cgaccacacc gatccggaac tcgctcaggc cgtacggcgg
     6001 gggcggcgcc gggagttcgc ggcgcacggc tgggccgagg aggacgtgcc cgacccgcag
     6061 gacccggcga cccgcgaccg ctcctgcctc gactggtccg agcccgcacg cgcgccccat
     6121 gcccgtgttc tggcctggta ccgcgacctc atcaccctcc gccgcaccct gcccgacctc
     6181 tccgaccccg acctctccga cgtcaaggtc gcgttcgacg aggaggcccg gtggttcggc
     6241 ttccgccggg gggacgtcct ggtggccgtg aatctgggga aggaaacggc catgattccg
     6301 gtcggggtgc ccgatgcgcg ggtgctggcg gcttgggagc cggtggaggg gccgggtgcg
     6361 gatggggtgc tgagcctggg cggggagtcc tgcgtggtgc tgacggtggc gtgagcgggg
     6421 cacccggcgg gtggggctgg gcggggggcg gtgcgcaact cggcgctacg aggtgccgct
     6481 gcgcccaccc gtgccgcccc ggcggcacga ttgcccgcag ctggggcagg caggtcagcg
     6541 ggggcgcgcc ccttcagggg cgcggggaac tgcgcgatca gccacatacg acccgcagtc
     6601 gccgtgcaac acgcaccccc gacctatcag gcgcctcagt cctcgccccg cagatccgtc
     6661 accctctcca gcaggatcgc ctcccacgtg cgccgcaggc gaccccgcag caccggcagc
     6721 ggagcggcgc cgcggccctg caccccctcc gcgagggcga tgagcgtgtc gcagcgggcg
     6781 agccagaggc cgcgcaggca ggggcgggcg ccgtagcccg cgagggtggc ggcgcggacg
     6841 gcggcggggg caccgacggc cgtggcgagg ccggcgatgt cctcggcggg gtcaccgatg
     6901 accgcgtcgg cccagtcgag gacgccacgg acccggccgt cggcgctcac gacgaggcgg
     6961 tcgcccgtca gcccgtggtg gaccagcacc gcggccggcg ccgtcagttg cgcggcgctc
     7021 gcgggcgtga gctgcccgag ccgagccgcg tcgaactcgt cggcctcggc gaggcgccgc
     7081 gccgcgcgcc cggcggccgt acgcaacgtc tccagggagc gtggggccgg ccggggcacc
     7141 ccgagcgtct ccacctgccg cagcggcacc tcgcgcagtc ccgtgaggag tgccgccaga
     7201 tcggcctcgc ccacggcgga cacgtcgtgg tcctcggccg tgccgccggg cagcctggtg
     7261 tcgagcgtgt aggtgaggcc ctcggaccac tcgccggccg cgacgctcac cgggacggcg
     7321 acgccgatgt gcgggcggac caggtcccgc agccgcagtt cgcgccgctg gcgtccgacg
     7381 gcgtgccggt cggtggtcag gcgcagtacg tggcgggtgc ccacccacca ggtgcggtgc
     7441 gcctcgtccc cggcgacggg ccgcacgtcg gggccgccgc cccggccctc cccgttcttc
     7501 aggagggaac ggaccagccg gcggacgctg tccgcggtgg gtgtcggtgc ctgggtcatg
     7561 gtcgcgccgt cgtccggggg ttcaggggaa cggggatacg cggtcggtca ctccactgtc
     7621 gccatctccc gcggggtgtt gttgaggcgc cggccgccgt cctcggtcac cgtcacgatg
     7681 tcctcgatcc gcaccccgaa acggcccggc agataaatac ccggttcgac cgagaagcac
     7741 atgccgggca cgaggggccg ctcctcgccc tcgaccatgt acggcggttc gtgggtggtg
     7801 acgccgatgc cgtgcccggt gcggtggatg aagcggtcgc cgtacccggc ctcggtgatg
     7861 accgcgcggg cggcccggtc gacgtcctgg caggcggcgc ccggccgtac cgcgcggaag
     7921 cccgcctcct gggcggcgcg cacgatgtcg tgcacctcgc gctcctcggc ggccggttcc
     7981 ccgacgtgga ccgtgcggga ggtgtcggag ccgtagccgt ccttgaggcc gccgaagtcc
     8041 aggacgacca tgtcgccgcg tccgatgacg cggtcgccgg cctcgtggtg cgggttggcg
     8101 ccgttcgggc ccgacgcgac gatggtgaag tcgacctgcg agtgcccgaa ccgccgcagc
     8161 aggccggcga gatcggcggc gacttccttt tcccggcgcc cggcgaaggg gacctgccgg
     8221 atctcctcgt acgcccggtc ggcggccgcg cccgccgccg ccatccgctc cagctcggcc
     8281 gtgtccttca ccgcccgcag catcggcagg ccctcggtga gcgcgacgta cgtcgtctcg
     8341 ggcaggcgcc gccgcaggcc gagcagatgc agcgcccagg tgttgtcgct gaccccgaag
     8401 cggccacgcg gaccgaggag ggagacggcc gcctcgtacg ggtccttggc gtcggtccag
     8461 tcgcggaggg tgagcgcggg tccgccgggt gcctccgcgg cgtccggggc ctccagggtg
     8521 gggacgacca gcaccgggtc ctcgccgtcc cgcagcacca gcatcgtgaa ccgctcggtc
     8581 tccggcggcc ggtggcccgt cagccacacc aggtccgggc cgggcgcgac gagcagcccg
     8641 tcgagcccgg cgtccgctgc ggcccgtgcc gcccgccgca tacgggcccg gtagtcgtcg
     8701 gtcgtgaagg gcgcgggtgt ggcatcggtc gtgacggtcg cgggcccgtc gctgggcgtg
     8761 ccggtcatcc atgcctccgt ctgctcggag ttccctgaag ctacgggcag catcctgccc
     8821 ctccgccgca gcgcacgcga gccgattgcg ccgtggcgtc cactgtcgtg cggcttcggc
     8881 gtcagctctc ccgggcgagc cgcgccccga ggagcagcag cacgcccggt acgaggccca
     8941 gccgctcttc ccggccgcct cccccatgct cgccggctgc cccttcgaac ggcacgcctg
     9001 ccacagggtc cgcgcgccga agacaacgag gacccggcta atgcctgagg gttgcccatc
     9061 cgttaggtct aatgcttgga ttcgactgtt ccattaagca ccgcccgagg aggcgtacga
     9121 cgatgctcgt actggcgcac atcagtgatc tgcatctgga cgggagcgag cgggcgaccc
     9181 ggcgggccga gcgggtgcgg gatctgctgt gggggctgcc ggggcgggtg gacgcgctgc
     9241 tggtgaccgg ggacatcgcg gaccacggca cggaggccga gtacgaggag gcggcgagca
     9301 tcctgggcct gcgggagggc ggggctccct tcccggtgct cacctgcccg ggcaaccacg
     9361 acagccgggc gccctaccgc aaggcactgc tcggggagcc ggccgccgac gggccggtca
     9421 acagcgtgcg ggtcttcgcg gacgcggccg tgctgatgtg cgactccagc attccggggc
     9481 aggacgaggg cgaactggac gcccagacgt acgcctggat cgaggagacg ctcgacgaac
     9541 tcgacggcga gcggccggtc ctgctcgcct tccaccaccc gccggtggca ctgcaccatc
     9601 ccctgccgga cgcgtaccga ctgggccggc ccgccgctct ggcccggctg ctggggcgtc
     9661 gcccggagat cgcgggcctc gtcaccgggc acgcccacac ccccgccgcg accaccttcg
     9721 ccgggcgtcc gctcgtcgtc gggcccggcg tcacctggac gctgcggctg ccctgggagg
     9781 gcgaccaggc cgcggaccgg gaggcgccgc ccgggctcgc cttccatgtg ctggacgacg
     9841 agggacggct gacgagccac ttcagggtgg cttcgtaagg gctccacagg cttccggccc
     9901 ggctcctcag gtgacgactc ccggtacggc cgccaggtgc tgtcggttgc cggcgggcgt
     9961 tcgcccgggc cgcggtcgag cacgcgaccc gggcgtcggc tcagcccgcg tgcgccggcg
    10021 cgaaggacag gaccggtggc cggtccggga cgaagccgtg ggctcggcgg gccaggaact
    10081 cgggcttgta gcggtcgacc tgccggtgcc agttgaggat gccggacagc cagttccgca
    10141 ggtcggtcac atagccgtcc atgatggccc gcgcctcctc cgacagctcg aagtcgtcgt
    10201 agacaacggg gagttcatgg gcgaccacgt gctcgaactg ccgcatccgc tgggtcatca
    10261 gatcgtggac cacgccgagc gcggtcgggt agtcgcagcc gaagaagttc tgcacgacga
    10321 ggatcgcgtt gtggacctct ccctcgtact cgatctcctt ctggtacgag aagacgtcgt
    10381 tgatgaggca cgcgtagtcg atggccgcgt tctccagtga gcggacgggg ccgctgcggt
    10441 agaccgcgtc cgggatctgc gggccgtggc ccatccggca caggctgagg gtgaggtcgg
    10501 agccgaaggt ggcgcgccgc atctccaggt agtcgaccgg gtcggggaca cggttctgga
    10561 tctggttgaa gagctcccac acccagctct cggtcatctt gtcgacggac gccttcaggc
    10621 cgcgtcgctg gtcgggggtc attcccgccg tcgtacgcgc ccagaggtcg atgagtcccc
    10681 gttccatgcc gttgaccggg acggtgaccg cctcgccctc gacgggcatg cagtcggaca
    10741 gccgggccgt ggtcagacgg gcggcggcga ggtcgcggcg gtggccgaag acgagcgggt
    10801 agtagtcgtc gccgtaggtg ccccaggcca accactggga gctgaggtcc agttgctcgg
    10861 gtgtcgcgtc cgggtcgagg ccggccgcgc agagcggaag gtcggcggcg gcgagcctct
    10921 cctcgtccca gacgccctcg ctgagcatgc ccatcgcgtg catccacgtg gtgaggcggg
    10981 ggcgggcggc gtccaggtgc gggcagagtt ccacctcgaa cggcatgtag aaatccggga
    11041 gtcgggacgg cccgaccttc tggtacggca catgcgtatg ggcacgcagc cgctccgccg
    11101 cggcggtcgc gagcagcgcg cccacgttgg cggcggccgt gccgaacccc ggccgggtga
    11161 ccagtgcggg gccggacagg accgcgccgc cgaagtcgag ggggccgcgc gaggaggcgg
    11221 ccccctcgtt catgtagcgg ctggagcgca tgtgccactc gtggccgccg gactgccagt
    11281 cctgcagccc cttcgtgtac gccgcgacgg cggcgacctc gtccggggtg aggcccttct
    11341 ccagggccag cgcgggtact tcggtgagcg cggtgttctc gaactggtgc agtcgggagg
    11401 tgaggatgtc gttgacggtc tcggcggcct gctgggtgcc gcagccgaag aaggtctcca
    11461 ggacgagcac gccgttgctg ttctcgccct cgtcctcgac ctcccgctgg tacgagaaca
    11521 ggtcgttgcg caggtggacc gcgtcggaga aggtctccat caggacgcgc aggggcctcg
    11581 actccgcgac gggcgccggg acttcggcgg tcgcgtactc gacgagaccg gcggaccagg
    11641 gggcgccgcc gaccttgcgg cgcatctcga tgtactcgac cgggttggcg atccggccct
    11701 cgttgatgtt ggacagctcc cacatcgact cgttgagcag atgctcggtg gccacggcga
    11761 aacggcggcg ccagtccatc gacatcgacg gcaccgtacg cgcccagagg tcggcgaggc
    11821 cggcctccac cgggttccgc ggttccggta cgggggtcga gaggtccagc ggcatgaaga
    11881 gcgggagtcg gtcgaggtgg gccttgccgc cggcgcggtc ctgggaccgc ttgaagagct
    11941 ccaggaagtg gtcgtcgaag aagaacaccc acacgtacca gtcggtgatg agcgagagtg
    12001 ccgggccgtc gcagtctggg tgggtgtacg cgcacagcag accgtagtcg tgcgcctcca
    12061 ggtccttctg gtcccatacg ccggagccct ccagcatgcc catctcccgg gcccacccgg
    12121 tcgagtgggc ccgcgcctct tcgaggtggg ggttcagccg tgcgggatac ggcatgtaga
    12181 agtgcgggag ttcgaacggc tgcgtcatgg ccggggccct acccgtcgcc tccggcgggc
    12241 atccggacag gggcacatga tcacaccatc gcgtgaatcc gggcggtttt ctcgccggcc
    12301 ggctttctca gcctcccgtg cgtacggccc tgcccacgtc cgcccggcgc tcccccggtt
    12361 cttcggtcgg ggaagcgcct cggtcagacc ctgacctgga tcagtgcgcg ggtcccgctc
    12421 gtccgccagc gctgtccctc ggcggccacg agggcggcct ccttctgcgc ggtcaggccc
    12481 acgatcacat cggacttgag ggtgcgcagg gcggcgaccg ggccggggaa gtacgccgtg
    12541 acctccgcga agggcgtggt gggaggccag agccggtcgc cgaccaggcg gcggtagttg
    12601 aggtcgccct tgaggagggt caggtcggcg gaggcgaagt cgtcgcgcag gtcggccggc
    12661 atgtccgcgt acggcaaggg agcgcaggag aaggggtgag cgcgcaggac gatgcggccg
    12721 tcggacagtg cggaccagag gcggtgcccg gcgtcggtct ttgcggcgac cagatggcgt
    12781 acggcgtcga gggtgtcggc ggtcgtggcg tccgagacga agtacgggta cggcttcagg
    12841 tgcagtacgg cgcggtcgaa gtggccgtgg gtgaggagat ggtcgatgag gagcaggtcg
    12901 gggatcagtt cgcggcccgc gttgtcggcg accaggcaga gcgttctcgc gccggcgccg
    12961 gcgcccgcgc ccctgccggc gcccgtcagc aaggacatca gcgactcgct gtcgtccgcg
    13021 accagttggg agtcggcggc ggttgcgtcc tcctcggcgg tctggatgcg gaagccaagg
    13081 tccgcgcggt tgccccagag ggagccgtgc aggagggcct tgagctggtc ggggaggggg
    13141 tgctgggcca aggtgccgag agcggtgagt tcggcggccg cctcgggggt gtccagttcg
    13201 gcgagcttga aggggcggaa cggatcggtg ccctgccacg ggccggggcc gaagtggccg
    13261 accgcgcgga ggagttggcg gtagaagcag ctctcggcga cgaggaaggg gagggagaac
    13321 caggagcggc cggcgtggcg gcgtacgttc caggtgtccc accagtcgtc gtcggccggt
    13381 ggttcgacgg tgccgtggag ggtgttcttg agcaactcgt cgagggctcg gcgctgttcg
    13441 gggccgtagg gcgtggcgtc ctggaccttg cggatgaggg cggggtgccg ttcggcgagg
    13501 acgctgtgcg ggaaggaggt ggggtcgtcg cagcggatca cgggggcggt gtcaggcatg
    13561 gccgggggtc cctccggggc cggaaggcat gccgggcggc agggagacgc ccttgacctt
    13621 ggtgtcgagt tgcttgccgt agccggcctc ggtccacacg tacttcttga actgctccgg
    13681 cgtcagcggg cccggccagg ggctgccgcc ggggtagaac accgacccgc acgacgagca
    13741 gtggtgcgcg ggacgccaca gtcgttcggc gtgcgcctcg ccggccacga cggccttccg
    13801 ttcgcgcctc tcgccacgga ccaccacgat ggtgccgacg aagagcagca cggcgaggag
    13861 cgaaccgccg atcgtgtaga gcggtttgtc gttctgtacg ccgctgtagg cgaggccggc
    13921 gccgatgccg gccatcacca tgccttcgag gaagtgcacg aggctgtcgg atccgtcatg
    13981 cacgcccggg ctcctcgcca gccggtcggt gaggccgccg cgccgggact ccggatcggc
    14041 gcaggcgtcg gcgaccgtac gcaccgccgg gcccgtaccg ccacagccgg gacacaccgc
    14101 cgcgaccggc tgcccttcgg gacgcccgta cgtctcagtc ttctctgtcg acatgcacat
    14161 acgctaacgg tcgaacacat atgcgccgac ggccgaccga tgcccgctcg catcggtcgg
    14221 ccgccggcag tggggggtgg cggtcagtgg ggggtggcgg tcagtgggcc cggcctgtcg
    14281 gccgagggct cagaaggtca gcttccagct gttgagccgg ccggtgtccg cggacgccac
    14341 gtcctggacc cgcagcttcc aggtgccgtt ggcgacctcg ctggaggcgt tcaccgagta
    14401 ggtggtgacc aggttgtcgg cggagtccga gctggaggcc ttgagacggt aggtcgaacc
    14461 gtcgggggcc accaggtcca ggaccaggtc accgcggtag gtgtgggtga tgtccacgcc
    14521 gacctggagg gtcgagggcg cgttgccggt gcggccgctg acggagatcg aggactcgat
    14581 cgccgcaccg ttgtccggga tggagacggc cgtggcgttg gtgaaggtgg tgccccccgt
    14641 ggagcccccg ccggagccgc cggtcaccgc ctgcaccgtc ttggctgcgt cggcgaggcc
    14701 cgcgccacaa ccgccggagc aagttccggg cagagcacgc gagttggtct tgatcgcgga
    14761 ctcgatctgg gccggggtca gcgcggagct cgccgacttc agcagcgcgg cgaggcccgc
    14821 gatgtgcggg gcggccatgc tggtgccctg gtagtagtcg tacgtctcgc tgcccgggcc
    14881 cgaggcgccg gtgttcagcg tggacaggat gccgcccgac gcggtggtgc gggtatcgcc
    14941 gccgggggcc gcgatgtcga cgaccgagcc gaagttcgag tagtacgagc gggagccggc
    15001 gcggttggtg gccgccaccg agatcacgtt ggcgcagctg gccggagagt agttggccgc
    15061 gttggcgttg ctgttgcccg ccgcgacgac gaccgtggtg ccgcggttca cggcggagtt
    15121 gatcgcggtc tgcgtcgcgg tggtgcaggc gccgctaccg ccgaggctca tgttgatgac
    15181 cttggcgacg ttggtgttgg cggggacacc ggagacggta ccgccggacg cccaggtgat
    15241 cgcgtcgatg atgtcggagt cgtagccgcc gcacttgccg agcacccgca gcggggagac
    15301 cttggcgccg taggcgatac cggcgacgcc cttgctgttg ttggtgacgg cggcgatggt
    15361 gccggcgacg tgcgtgccgt gccaggagga ggtggtggcc gtccagtcgg tggcgcactc
    15421 cccgtccgag gtccagtcgc ccgggtcggc cgggttgctg tcacggccgt tgccgtcgtt
    15481 ggcgacagcg gtgtcggcga tgaagtcgta gccgccgacg atgttcgcgg cgaggtccga
    15541 gtgggcgacg taaccggtgt cgatgacggc gaccgtcact ccggagccgg tcaccgtgtc
    15601 ccaggcgccc ggcacgttca tgcccgcggt ggactcgtag aggtcccact gcttgctgta
    15661 ctcggtgtcg ttcggggtgg ccagcggctt gttcaggcgg tccgggacga cataggcgac
    15721 ctgcgggtcg gcctggtact cggcgatgac gtcggcgacg tccgtcttgg tgagatcctc
    15781 gcccaggtcg acgagggccg cgccgctgcc cagccggcgc tggaagtcga ggctctcgcc
    15841 ggcctccttg cccttggcca cggcgtccgc gtcggcggcc ttgttcgact tggcctcggc
    15901 ggcgccggac ttgtagccga cgatcaggcg ctcggcggtg gtaccgggcg cggcctcggt
    15961 ggcaccggcg acggcggggg ccgcgtcagc cttggcggac ggggcggcga cggcgaccga
    16021 ggaggtcatg cccgccacca gggcgacgga gaccgcagcg acggatatga gcttccgtcc
    16081 ggcggtacgg gagggggagg tacgcaaggg cttcgccttt cgtggcctgc tcatgtcagg
    16141 ggaggagcgg caatgaaacg cttcttcttc gaagcggcgg gggtccagaa agggttggcg
    16201 cgaaggccgg ccaggcgcga gccgtgccac caggggttac ctatggttcg gctgtgcgat
    16261 gacattaggc aaagcgcagg tcatggggat acggggaaaa ccctcgaccc ccggggaact
    16321 cccctatgcc aggcggcagt cgggccggat gtgccgcttc gccgggtttg ccgaggcctt
    16381 gccgatgccc ggcgcatggc tggatccgac cggtcgaaca cggccgcggt gttgaacgcg
    16441 gcgccctcgg gtcccgtacg actcggtgga ccgccagccc caccatcccc ttggatcgga
    16501 cgtaccggat gtaccgcttg tccgcccgcc gcaccaccgg ccgaggcacc accggccgac
    16561 gcaccgcctg tcgcacggcc gcctgccgca ccaccggcca ccgcaccgcg gtcacggccg
    16621 ccgccgtcac cgtcgtggcc ccgctgatcc tcaccgcggg ggccgtcacc ccggcctggg
    16681 cgcacggcgc gccgaccgat ccggtgagcc gggtgtcggc atgctcgccc gagggcggca
    16741 gtcaggggtc ggcggcgtgc gaggcggcgg tcgccgcgaa cggcgcgccc ttcaccgcgt
    16801 gggacaacat gcggatcgcc ggggtgaacg ggcgcgaccg ggaggtcgtc ccggacgggc
    16861 agctgtgcag tggagggctc gcggactaca ggggtctcga cctggcccgc gccgactggc
    16921 cctcgacccg cctctccccc ggtaccacgc tgaacctgac gtaccggtcg acgatcccgc
    16981 acaccgggac cttcaagctg ttcctgacga aaccgggcta cgaccccacc gaaccgctga
    17041 agtggtccga tctgcccggg aagccgttcg cctcgatcac cgacccgccg ctgaagaacg
    17101 gctcgtacca gttctcggcg aagctgccgg cggaccgggc cgggcaccat gtgctgtaca
    17161 cgatctggca gaacacgagc acggtcgaca cgtactactc gtgttcggac gtggtgttcc
    17221 cgaaggcgaa gcaggccaac tccgaggcgg gcgacgggag ttcggcaaag acgcccgccg
    17281 ggagcgagga gaccgcctcc gagaagccgg cggccgagaa gtccgagccc gccacgaccg
    17341 cgccgacgga gtccacgcag gcgcctcccg ccgaagccgc cgacaacgcc gacgacgacg
    17401 cgcaggcggc cgaccccggc agccccgtcg cctccacgac cgacgagagc ggcgcccccg
    17461 ttccgctggt cgcgggcggc gccacggcgt tggcgttggt actggccgtg ggcaccgccc
    17521 tcttcctccg cggacgcggg cgccgctctc gtatcagcga ctgatcgggc aggcgatccg
    17581 gccagcggtc aagcaaccga ccggtgtctt acgtcagttg gtataggccg tcatctgtgc
    17641 aggccgtcag ttgtgcaggc cgtcagttgt gcaggccgtc agttgtgcag gccgtcagtt
    17701 ggtgtagacc gtcgcgccgc cctgggtggc gtccgtgacg ggcgcgtact tcgccgtgaa
    17761 gtagccggtg gcgaagcaca gggacgagcc ggaggtcttg gtgaacggct ggctggtgaa
    17821 gttgatgctg ttgtcgtcgt tgctggaggt gccggtgatg ctggccgcct ggtagacgca
    17881 gttgatggtg cccagcaggg tgcgcagcac gacggtggtc tggaggaccg agcccgccgc
    17941 cgggctgacg gtgacgacgc cgtccgaggt cacggtggtg gtgtagggca ggttgttgac
    18001 cgtgacgccg gtgacgccga gcacgccgac gacgttgctg gtgcagctgc cgaaggtgtg
    18061 ggcgtcgacc cgctcggtgg ccgtgccggg cgcggccggg ttgtcggtga ccgtggcggt
    18121 gaacgtcgac tcggcgcagg agacgccgct cgtgcccgtc gcgctggagt agaacttgcc
    18181 ggtcgtaccg gacgccagcg acgcgttgag cacgtcgccg accgcgaccg cgtcaccggc
    18241 gaggccgccg gtggtgagca cggtgtcggc ggcggaggcg gggctgacgg cggacaccat
    18301 cagggcggcg gtggtcgcgg cgagggcaag gagggatcgc gtacgcatgg ggtgcctctt
    18361 ctcaggaagc gggggccgca ggtgacggcc ctcggcaggt gcgggtgaca gccctcggaa
    18421 gaagcgggct gcggtgattg cgcgcgggag gacaccgttc gcgcggggga acgcggcgat
    18481 gccgcacggc gccgaacggt cgctgccgat ccgtgacacg ccttctccgt acgtgacgga
    18541 tcgacagcga ctgccggagg aaccggacac ggcccagtgg aggggaaggc gaccgtgccc
    18601 ggcaccgcgg cgagggggtg gtgctgcgtc gggccgcgca gtgcgttcag gtggtgtcac
    18661 ccacaccccg cctgcgacga ggagttcggg acggtgacat gcgctgcgcg tcggatccgg
    18721 cgccacggat ccgtggggga aacccgggag agttgtagac ctgctggaga gtcaacgtca
    18781 aggctgcata cggaagttgg tgagggccag aggtcgcggc gagggccgag accgaaggcc
    18841 atgggccaca aaaccaaagg tgagcgatgt tcacctttca caggtgtcgc acaaccgaca
    18901 tccttttgtc acaagcgcct tgacccctga aagtaaccac cggtaacttc ccaaatggct
    18961 actgcggcgt aacgagtaag cccttgcacc cacgggaggt gcacccaggt gtgcgccgca
    19021 accgctgtcc gcgccaggac aacgtgccgt cgaagcccca tttgcgatat ctgcaatgac
    19081 ttggaagtcc agggagcaca catggcctcg tcctcggacg ccgcggcgtc caccaacgaa
    19141 agacccgagg gtcccgaagc gtcaggcaga cgcgggcggg tccgcctgaa gcgcgccgcc
    19201 gtgatggcgg tgccggccac ggcggtcgcc gccggtctca tgatcctcac cgcgcagggc
    19261 gcccttggcg tccagttcgc catctccggt atgccgttcg tggtcaccgc cgacaagctg
    19321 gagggcgagg gcttcgccca gttcggctcg ctcgaccaca tgatcgagaa cagcccgaac
    19381 gagggcgaca ccggcggtca ggtgctggtc gtgacctcgg tcgtgaagaa cggcaagctg
    19441 acgaacctct gccagagcgt cgacctcggc ggcatccagc tggtcctcag cgccggcaac
    19501 aagggcacgc cggtgagcgt gaagaacctg gcgatcgact ccgacgacat ctcgggcgac
    19561 gcctcgttca acaacatcga gatcggccgt gactccagca cgttcgacaa ggtcgaccag
    19621 cagggcccgc ggggtgtcta cggccagcag gccgactcgg tcgtcatcac cgacctgtac
    19681 cagcacaact acgccgccac cgcggccgtc ttcaagctgc ccgacctgca catgagcttc
    19741 acgagcgagg gctgcccgca gtgagccgat tccgggaatg gagagggcac cggccgttcg
    19801 ccggtggtct gctgctggtg ctgggcgggg ccgagatcct ggtgaccatg aaagcgccgc
    19861 ttccggtcat cctgaagatc gggatgcagg gcctcgcggg ttatctcctg ccctcgctga
    19921 tgatcgtgtg cgggtcgctg atcatcttca accccgctca gcgcctgttc tactccatcc
    19981 tcgggatcat gctctcgctg ggcacgtggc tcacgtcgaa catcggcggg ttcgtcgtgg
    20041 gcctgctgct gggggcgatc ggtagcacgc tggccttcgg ctggctgccg gaccaggaac
    20101 cccggcggaa gcgctccgcg aagccgaagg gacagcctga acagcacgcc gcagagctcg
    20161 ggtaggtgag gctgttcggc gggtgcgggt tgttcgtggt tgttcgcgcc cacgcggcgg
    20221 agccgcaaat cgatacagcc ccgcgcccct ttaggtgggg cgcggggtcc ggcgtttaca
    20281 gggcggccgt gactgccgcc tcggacaggg ccgagcggag gcgttccgtg tcggtccagt
    20341 agcggtcgtg ggagagcggg acgcgccagt agaggccggg gcccgaggta cggcgcaggg
    20401 gtgggaccgc cacgtggctg ccccggccga ggacctggac gtcggccatc cgccactcgg
    20461 aggcgtcgcc cggtggcacc agccagtaca tgatgccgcc gtagccgtcc ttgatcacag
    20521 cgcccgactc gtccccgagg gacttcagcg cgagggtgcc gagggcgacc gggacgcgta
    20581 tcgcgttcca ccagcgcccg gccggcacgg tgcgtacttc ggggctgtag gaacacatcc
    20641 agcgcggggc cctgctgaca gtcatggcac tcaccggctc ttcgtggggg tgaggccgat
    20701 cctagggtcc tgtccaggac ccaacttgcg agtacgcgca gggaagttga cgccgtacgc
    20761 agcgcgcggc gcgcgttctc gccctgcgac gctaccgggc cgtagcgtaa cggggcttcc
    20821 acgttgtgct gttggaccgt actcgactcg accgcaggag gaccccccat gggccacccg
    20881 agccccctgg tgattgacgc gaccggccgt gacatccacg gtgaggccgc ccgtatccgc
    20941 gagacgggtc cggcgacccg ggtcgtgctt ccggggccgc acgatgtcga ggcctgggcc
    21001 gtgagcagcc ccgatctgct gaagcggctg ctcaccgatc cccgggtgtc gaaggacccg
    21061 cggcagcact ggccgaggtt cgccgccggt gagatcaccc cggagtggcc gctgttcacc
    21121 tgggtcgcgg tgcagaacat gttcaccgcg tacggcggtg accacaaacg gctgcggatc
    21181 ctggtctcca aggcgttcac ggcgcgccgg acggccgcgc tgcagccacg cgtcgaggag
    21241 atcaccaagg agctgctcga ccgggtcgag gagggcttcc ggcgcggggt gacggtcgat
    21301 ctgcggcagg agttctgcta cccgctgccg atccaggtga tcagcgagct gttcggcctg
    21361 cccgaggaac gggggctggt actgaaggag ttggtggaca agctgttcga cacctccgcc
    21421 gcgccgggcg agatgaacgc cgcctacgag cggatgtacg gcgtgctcgg cgaactcgtc
    21481 tccgccaagc gggagtcgcc gggcgacgac ctcaccagcg ggctgatcgc ggcccgcgac
    21541 gaggacgaca cccgactcag cgagcaggag ctgctggaca ccctggtgct catggtcagc
    21601 gccgggcacg agaccacggt caacctcctc gaccaggccg tgcactccct gctgacccac
    21661 cccgagcagc tcgcccatgt ccgggaaggg cgcgcgacct gggacgacgt gatcgaggag
    21721 acgctgcggg tccaggcgcc ggtggcgagc ctgccgctgc gctatgccgt ggaggatctc
    21781 gacctcgccg agttcggcgg tcccgagggc gtggtgatcg ccaagggcga cccgatcctg
    21841 gccgcgtacg cggccgccgg gcgcgacccc gagcggcatg ggaaggacgc cgacgtcttc
    21901 gacgtcaccc gtgccgacaa ggaacacctc gccttcggcc acggggtgca ctactgcctg
    21961 ggcgctccgc tcggccgtat ggaggcccgc atcgcgctcc cggcgctctt cgagcggttc
    22021 ccggtgctcg aactgggcgc cgccgaggag gagttggggc acgtggagtc gttcatctcc
    22081 aacggccacc gccgcctgcc cgtgcgcaag gcctgagcag gccgtttttc gcccccgccg
    22141 cccctacccg tcccatcccc caggggctgc gccccttcga cccccagccg cgggtccgtc
    22201 gtggttgc
//
