LOCUS       NZ_CP102512            34991 bp    DNA     linear   CON 11-FEB-2024
DEFINITION  Streptomyces sp. CA-210063 chromosome, complete genome.
ACCESSION   NZ_CP102512
VERSION     NZ_CP102512.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CA-210063
  ORGANISM  Streptomyces sp. CA-210063
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10859970)
  AUTHORS   Nielsen,J.B., Gren,T., Mohite,O.S., Jorgensen,T.S., Klitgaard,A.K.,
            Mourched,A.S., Blin,K., Oves-Costales,D., Genilloud,O., Larsen,T.O.,
            Tanner,D., Weber,T., Gotfredsen,C.H. and Charusanti,P.
  TITLE     Identification of the Biosynthetic Gene Cluster for Pyracrimycin A,
            an Antibiotic Produced by Streptomyces sp
  JOURNAL   ACS Chem Biol 17 (9), 2411-2417 (2022)
   PUBMED   36040247
REFERENCE   2  (bases 1 to 10859970)
  AUTHORS   Joergensen,T.S., Gren,T., Blin,K. and Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2022) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 05-AUG-2022
            Assembly Method :: Flye v. 2.9-b1768; Polypolish v. 0.5.0; POLCA
            polisher from MaSuRCA v. 4.0.5
            Assembly Name                     :: M642_aaa1.6.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 55.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 11:12:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,501
            CDSs (total)                      :: 9,410
            Genes (coding)                    :: 9,051
            CDSs (with protein)               :: 9,051
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 359
            CDSs (without protein)            :: 359
            Pseudo Genes (ambiguous residues) :: 0 of 359
            Pseudo Genes (frameshifted)       :: 141 of 359
            Pseudo Genes (incomplete)         :: 302 of 359
            Pseudo Genes (internal stop)      :: 23 of 359
            Pseudo Genes (multiple problems)  :: 101 of 359
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:19:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2160378
            Orig. end                         :: 2195369
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102512.1.
            Bacteria and source DNA available from Tilmann Weber, Dr.
            Professor, Novo Nordisk Foundation Center for Biosustainability,
            Kemitorvet, 220, 327D 2800 Kgs. Lyngby, Denmark.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..34991
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAPAA"
                     /region_number="9"
                     /rules="(AMP-binding and TIGR02353)"
                     /tool="antismash"
     cand_cluster    1..34991
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AMP-binding and TIGR02353)"
                     /kind="single"
                     /product="NAPAA"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..34991
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[15000:19991](+)"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      15001..19991
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
     misc_feature    306..321
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.05"
                     /tool="antismash"
     misc_feature    complement(307..318)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 20.32"
                     /tool="antismash"
     misc_feature    397..412
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    507..518
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.87"
                     /tool="antismash"
     gene            643..1980
                     /locus_tag="JIX56_RS09330"
                     /old_locus_tag="JIX56_09330"
     CDS             643..1980
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308269.1"
                     /locus_tag="JIX56_RS09330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09330"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_257538570.1"
                     /transl_table=11
                     /translation="MNSTSPRRRFARVAVASVALTGLLAACGGSDSGDDSSGASGPVTL
                     PFWGWANGQETLVKAFNASHKDIQLKYTKVTDQLTMQKQLSNAVKAGNAPCLLQNTAEY
                     VTTWVSQGALADITEYVGASEDKFNAGAWAGVQVQGKVYGVPTSSAPAFTIYRTDVFKK
                     YGLDAPATWDDFITAGKELKKHDIHITNYAGEDPSTLEVLAMQAGAHWYAIDGDSWKVN
                     FQDEGSLKAADVIQQIIDNDLNSKLSFADYAAVQRNYDKGGTATRQISTWQMSGMVQNF
                     TDSFGDWALTPWPTYKGEAAKTPAGTNQSGGMNLVTEQCEYKKQAAEAALWLSTDTDAV
                     KSMASPETGSGVMPALADSDAYVAEAISEKLLGDHYEPGKKVVTDSLGTVTTDWVYGPN
                     WTAMFTELQSEWGKVVSKEQKVTDLLAHMQEWTVKDLKSRGINVKG"
     gene            1993..2877
                     /locus_tag="JIX56_RS09335"
                     /old_locus_tag="JIX56_09335"
     CDS             1993..2877
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010351003.1"
                     /locus_tag="JIX56_RS09335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09335"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_257538572.1"
                     /transl_table=11
                     /translation="MIRSQRWKGAAFTVPFQLGFVFLYLLPIGYAVYESLFQEKQSGLG
                     LGGATREYSGFDNYRLGLTDSAFMGSILRVVLFACVQIPFMLLVSLVLALFLDALTSKA
                     ANRFRIVLLLPYMIPGVVAAIVWINLYSPEVGPLTPVGDFFGFDWNFFSPSMVWPSIGN
                     LLTWHGIGYNMVIIYSALQGVPRELFEAARLDGASEARIALNIKIPFVRGALVLTGLLS
                     IIQMLQIFNEPALFRRITPETVDDSFTPIMIIYNQAFNAGNYHYAAALSVLLALILGVA
                     SFLFFRLTSKEVD"
     gene            2874..3815
                     /locus_tag="JIX56_RS09340"
                     /old_locus_tag="JIX56_09340"
     CDS             2874..3815
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308316.1"
                     /locus_tag="JIX56_RS09340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09340"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_257550792.1"
                     /transl_table=11
                     /translation="MMATTTTTGSPEKSGTSGTSGVPPVRRITRADTASRGRGGQRFIL
                     LGLILASAYSLFPVWWLIVASTKDRVGLYQSNGMWFSDIHLWDNLRQLFTYGDGIFLRW
                     TANSFLYAGVGSLGGTLIALATGYGLARFDFPGRGVVFACVVGSFLIPIALLTLPLYLM
                     FSKIGLVDTPWAMLIPCLINPFSVYLAKVYTEATIPFELLEAARIDGAGELRIFFSIVL
                     RMMTTGGATVFLLAFVNTWNAFFLPLTVLRGEENWTLNLGLYNWTGKSLESGIDLTSLV
                     LTGALLSIVPLAIMMTAMRRYWRSGVTLGALK"
     gene            3895..5517
                     /locus_tag="JIX56_RS09345"
                     /old_locus_tag="JIX56_09345"
     CDS             3895..5517
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308268.1"
                     /locus_tag="JIX56_RS09345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09345"
                     /product="family 43 glycosylhydrolase"
                     /protein_id="WP_257538573.1"
                     /transl_table=11
                     /translation="MTVAHNPVIRGFAPDPSLIRVGEWYYVATSSFEWFPTIPLHRSRD
                     LAHWEYAGHVRGAAPGGSLAGVPDSGGVWAPSLSWDGERFWVVYTIVRSVGTRYFDLDT
                     YVSTAAAVDGEWTAPRRVASHGFDPALFHHEGRLWLLNMQSDHRPGGKRFAGIVLTELD
                     RSTLRPLGDTHLLLQHDKLIEGPKLLVHDGWFHLVLAEGGTGFEHGVRVARSRSLTGPY
                     ELDDLPLLTTRDDPKVPLQKAGHAELVETPTGEWFLSHLTARPLHTDQGMRCPLGRETA
                     VQAVAWDAEGWPRLRQGGWHPAVEVEVPTVPGASGESTSTSTSTSAPVVRGDTLSWPWS
                     SLRAEPDASWVDATARPGWIRLRGRQGPESLWDQSLLAQRVTEHRAEVEVTVEARPRTF
                     GEAAGLTLRYNAASYLTLDLTWAEPEGEPQRGQQWRGEGRTVLSLVERDDEGARQVAEV
                     EVEAGRPVTLGASVDGAEARFWYLRDEVRTPIGPVLDFSRLSDDYGSKLRFTGAFAGIH
                     AQDLVGAAFTADFGGFRLVCGEE"
     misc_feature    complement(5880..5896)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.14"
                     /tool="antismash"
     gene            5934..6974
                     /locus_tag="JIX56_RS09350"
                     /old_locus_tag="JIX56_09350"
     CDS             5934..6974
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482036.1"
                     /locus_tag="JIX56_RS09350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09350"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_257538584.1"
                     /transl_table=11
                     /translation="MVRGGSATAGPTLAVVAREAGVSVPTASKVVNGREDVAPETRRRV
                     TEALDRLGYVRRPRFEASKPPRMVDLVVHSLESSWSGAVLHGVEQAAHDAGLEVVVSAG
                     LTRTRGARPERGWFDKLTARGSAGVLFNLAELSPAQYSWLTQHRIPFVLIDPVLEPPPG
                     VVSVGAANWQGGTTATEHLLALGHERIAVIAGYRRKMCSSARVAGYRSALMAAGIPYRS
                     EYVRYGNFMETASRHRMLQLLDLPEPPTAVFVCSDKMALGAYEALAERGLRVPDDISVV
                     GFDDLPEARWANPGLTTVRQPLSEMASTALRLLVRMMEGDQPEGTRTELSTRLVERAST
                     GVLRSA"
     gene            7166..9169
                     /locus_tag="JIX56_RS09355"
                     /old_locus_tag="JIX56_09355"
     CDS             7166..9169
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114212.1"
                     /locus_tag="JIX56_RS09355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09355"
                     /product="sulfatase"
                     /protein_id="WP_257538595.1"
                     /transl_table=11
                     /translation="MSHIRSPQLPGPTPAPDDDTAPEDAAPPEREAVTETKAEAEEPAE
                     PDTGKPEPEAKPAPEPEPEAEPAAAPDPAAEPAPESEAESAAAPDPEAESAPAPDPEPA
                     STSAPAPVAPPSGWRTKHPRAARAVAWAVTGLAVALVMFVLLVPNDVTNIEVGRFLRIP
                     AEGILVAALLLVLPPRARRVAVVVVGVVLGLLMIVKVLDMGSYWTLDRPFDLVLDWILL
                     DDAQSFMKDSLGGAVARVATIGVIALALALPALMTLAVVRISRLMVRHRHTASRTLLVL
                     GTAWITCSTLTLEVADTPVASHSAATLVENRIEAVSDGLKDGEAFEKQAAVDAFADVPP
                     DQLLTGLRGKDVLITFIESYGRSAIDDPQMGEPLGETLTQKTKELEEAGYASRSGWLRS
                     PITGAGSWLGHSTFLSGLWIKNQSRYANLVASDRLTLTEAFRRTGAWRTVGIVPGTQMA
                     WPEGKYFGLDHIYDSDQLGYKGPKFSWSTMPDQYTLKAFEELEHGKRDREPMMAEIILT
                     SSHNPWAPIPSTIPEERIGDGSVYHSLQKAEGKDPKEVWKDPSDVRDEYRKSIQYSVTS
                     LVDYVAKYGSKDTVLVFLGDHQPNKTVTGANPSHDVPVSIVAQDPEVLEKIADWDWTDG
                     LKPADDTPVWRMDKFRDRFMTAFGPQGAGNRS"
     misc_feature    7170..7183
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.71"
                     /tool="antismash"
     gene            complement(9166..>9534)
                     /locus_tag="JIX56_RS09360"
                     /old_locus_tag="JIX56_09360"
                     /pseudo=""
     CDS             complement(9166..>9534)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009293458.1"
                     /locus_tag="JIX56_RS09360"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09360"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="DPAYTSRWGAQHWQKPLTRTTRTTTRHGAAAVAIGRRAQGHPIRR
                     RTAPPPAHRSDEQGHRTVQARPGIPGREGTRPRIPGPRTRSVRAGRGAKAGDQNTQYRS
                     GCSAEHESWQQDSLPLSL"
     gene            complement(9602..10258)
                     /locus_tag="JIX56_RS09365"
                     /old_locus_tag="JIX56_09365"
     CDS             complement(9602..10258)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JIX56_RS09365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JIX56_09365"
                     /product="hypothetical protein"
                     /protein_id="WP_257538597.1"
                     /transl_table=11
                     /translation="MSWDGDRDDDVRELRRLLAVPAERDLPAGRRIQREEHLMRSWRTM
                     EKERTGGREHGRRVRKRFAWGLAAASIVAGVAVAVPVPGGTETPAYAVEKNPDGTLTIS
                     VRDLDWWGDPQHFERLAREIRAAGFTAIVDKIPAGKTCRLDRGTPLNQQKTGDGKGGYQ
                     YVMTHADAYVVEEYLPGSGPKGSDMRTAQAFRYMFFKGQVKPCDPVSRPQLKPPQ"
     gene            complement(10255..10893)
                     /locus_tag="JIX56_RS09370"
                     /old_locus_tag="JIX56_09370"
     CDS             complement(10255..10893)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559073.1"
                     /locus_tag="JIX56_RS09370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09370"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_257538599.1"
                     /transl_table=11
                     /translation="MEPLFRARVRAGDEDSFRVLFREHGRAVYNHCFRLTGDWSVAEDC
                     VSLVFLEAWRIREKVDPHGGSLLPWLLGIATYVVHHRRRTARRHRALMERMPPPGLLPD
                     FADEVVGRLEDQERIAALRKALDQLSRPDREVLALCVWAGLDYAATAEALGVPVGTVRS
                     RLSRARGRLQKLTQKNLDGDTEPAAARRQQTGDRHEAVRPSGDNGRGLR"
     misc_feature    10929..10944
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     gene            complement(11107..11766)
                     /locus_tag="JIX56_RS09375"
                     /old_locus_tag="JIX56_09375"
     CDS             complement(11107..11766)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308252.1"
                     /locus_tag="JIX56_RS09375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09375"
                     /product="hypothetical protein"
                     /protein_id="WP_257538601.1"
                     /transl_table=11
                     /translation="MFRTARVLLPLALLPLLLTACGTEKVVAAGREPLMPAPDPAELHA
                     RAEALGIAPGLVHVTESPGFMLARQSVGVYGDDGFSAVYWSRKNSAQLLLLVDHGTMNA
                     QNCPEHPLGQGTGTSVGCERDGDTWYRTSAGQHEYAVPEDGHVVRISAATAAVDRDVLR
                     AAALAAHRPTDAELAFLLPPRHHDKPPPPHDGMPIQRGDLPPAGDGAPNNEVGTSG"
     gene            11946..12350
                     /locus_tag="JIX56_RS09380"
                     /old_locus_tag="JIX56_09380"
     CDS             11946..12350
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007500985.1"
                     /locus_tag="JIX56_RS09380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09380"
                     /product="VOC family protein"
                     /protein_id="WP_257538603.1"
                     /transl_table=11
                     /translation="MTPRLDAIGMVASDMAASVTFYRRLGFAFPEGAENQPHAEAQLPG
                     GLRLMLDTEETVRSFFPQYRPGTGGGAGLALLCDSPAEVDAVYEELVNAGYQGELKPWD
                     AVWGQRYAVIQDPDGNGVDLFAPLPTSAPE"
     gene            complement(12424..13119)
                     /locus_tag="JIX56_RS09385"
                     /old_locus_tag="JIX56_09385"
     CDS             complement(12424..13119)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999810.1"
                     /locus_tag="JIX56_RS09385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09385"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_257538605.1"
                     /transl_table=11
                     /translation="MYAERASRLGGAVVWTNTPSGSGEPGAGRILPDGCMDLLWNDGRL
                     LVAGPDTTAYVTEGPPSSWAGLRFYPGTAPAYLGVPAHELRDRRVELAELWSPALVRRL
                     TARVNAAADPASGLEEVALERAADGGRPDPLLRRIVVALDAGRPVAATADELGLGVRQL
                     HRRSLAAFGYGPKTLARVLRLRRALALARDGVPFAETAARTGYADQAHLARDVRELAGL
                     PLGELLGGR"
     gene            complement(13319..14443)
                     /locus_tag="JIX56_RS09390"
                     /old_locus_tag="JIX56_09390"
     CDS             complement(13319..14443)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308290.1"
                     /locus_tag="JIX56_RS09390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09390"
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="WP_257538607.1"
                     /transl_table=11
                     /translation="MQPASQSPPPPESPHGRLHRARALYRNVSKRRTAWLLLKDTVNSC
                     IEYRILGLAAEAAFFTLLSVPPLLLSMIGLLGYVDDWTGADTIASLELNLLEASRTVLS
                     DKGVAEIAQPILDDVMRGGRPDVISIGFLFALWSGSRAVNVFIDTITVMYGLDGVRGIV
                     KTRLMAFLLFIVALLIGSVALPLMVAGPDAVVRIVPWSATVVQVLYWPVVIVLSIVFLT
                     TLYHVSVPVRSPWVEDVPGSLMALGMWVLGSFLLRIYLTSTVEGATIYGSLAAAVAVLL
                     WIGVSAFAVLVGAAVNAAIDRVWPAAATAAARAANERLREEQAAEYVARAAAARSHDPE
                     DPDMPSEFPERWSRFLPPEDVTSRLRSPVKKGDD"
     misc_feature    14589..14603
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(14993..15008)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.14"
                     /tool="antismash"
     gene            15001..17511
                     /locus_tag="JIX56_RS09395"
                     /old_locus_tag="JIX56_09395"
     CDS             15001..17511
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: PCP (30-100). E-value: 1.2e-10. Score:
                     33.4. Matches aSDomain: nrpspksdomains_JIX56_RS09395_PCP.1"
                     /NRPS_PKS="Domain: TIGR02353 (124-829). E-value: 8.5e-241.
                     Score: 792.8. Matches aSDomain:
                     nrpspksdomains_JIX56_RS09395_TIGR02353.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     TIGR02353"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308345.1"
                     /locus_tag="JIX56_RS09395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09395"
                     /product="Pls/PosA family non-ribosomal peptide synthetase"
                     /protein_id="WP_257538609.1"
                     /sec_met_domain="PP-binding (E-value: 1.6e-09, bitscore:
                     37.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR02353 (E-value: 1.3e-238, bitscore:
                     792.8, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLPVPRHVVEKPGEVQAAEPDAAESYTATERLLAELLAGVARIE
                     HVPAESHFFDDLGANSLTMAHFCARVRKHPDLPSVSIRDVYGHPTIRGLAAALTEAPPP
                     PAAPPVPAEVTPPGNTFRYVLCGALQLLLFAAYSLLATSGYVLGYEWVADASGIVAVYL
                     RSALFGALAFLALCTLPVVAKWLLIGRWKPGEFPVWGPAYLRFWIVKALLRTSPMILFV
                     GNPLYVLYLRALGARIGPGVTILSRTLPVCTDLLTIGAGTVIRKESFFLCYRARAGRIR
                     TGPVTLGRDVFVGEHTVLDIDTALGDGSQLGHSSALRAGEAVPAGQSWHGSPARRTDVD
                     HIRVAPADCGRLRRAGYGCAALLQTLLLYVPLTLGGAYLLLTAAPSLDTLLDPASRHIA
                     SARFYLEALALSLVLFAGSLVVAAVVVFVVPRLLRPLVRPDRVYPLYGFHYSVHRAITR
                     LTNLKLFTWLCGDSSYIVPYLKALGYDLSRVEQTGSNFGTEVRHETPYLVTVGSGTMVA
                     DGLSVMNADYSATSFRVSRTAIGGHNFLGNFIAYPVGGRTGENCLLATKVLVPLDGEIR
                     EGVGLLGSPPFEIPRSVERDTRFDHLREGDELRRRLAAKNRFNLRSMGLFLFLRWLHTF
                     ALTVLGFAAFDLYGHGDGMAGLLALAALPLAALVFTVLYYTLVERSMTRFRPLRPRLCS
                     IYDPLFWRQERLWKLRDTHIQVLSGTPYKNLVWRLLGVRIGRRVFDDGVVITERTLTAV
                     GDDCTLAAGSKIQAHSQEDGTYKSDHVTIGARCTLEVGAFVHYGVVLGEGAVLAPDSFL
                     MKGEEVPPHARWGGNPATETTGER"
     misc_feature    complement(15028..15043)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.87"
                     /tool="antismash"
     aSDomain        15091..15300
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JIX56_RS09395_PCP.1"
                     /evalue="1.20E-10"
                     /label="JIX56_RS09395_PCP.1"
                     /locus_tag="JIX56_RS09395"
                     /protein_end="100"
                     /protein_start="30"
                     /score="33.4"
                     /tool="antismash"
                     /translation="ERLLAELLAGVARIEHVPAESHFFDDLGANSLTMAHFCARVRKHP
                     DLPSVSIRDVYGHPTIRGLAAALTE"
     aSModule        15091..17487
                     /domains="nrpspksdomains_JIX56_RS09395_PCP.1"
                     /domains="nrpspksdomains_JIX56_RS09395_TIGR02353.1"
                     /incomplete
                     /locus_tags="JIX56_RS09395"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        15373..17487
                     /aSDomain="TIGR02353"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JIX56_RS09395_TIGR02353.1"
                     /evalue="8.50E-241"
                     /label="JIX56_RS09395_TIGR02353.1"
                     /locus_tag="JIX56_RS09395"
                     /protein_end="829"
                     /protein_start="124"
                     /score="792.8"
                     /tool="antismash"
                     /translation="LCGALQLLLFAAYSLLATSGYVLGYEWVADASGIVAVYLRSALFG
                     ALAFLALCTLPVVAKWLLIGRWKPGEFPVWGPAYLRFWIVKALLRTSPMILFVGNPLYV
                     LYLRALGARIGPGVTILSRTLPVCTDLLTIGAGTVIRKESFFLCYRARAGRIRTGPVTL
                     GRDVFVGEHTVLDIDTALGDGSQLGHSSALRAGEAVPAGQSWHGSPARRTDVDHIRVAP
                     ADCGRLRRAGYGCAALLQTLLLYVPLTLGGAYLLLTAAPSLDTLLDPASRHIASARFYL
                     EALALSLVLFAGSLVVAAVVVFVVPRLLRPLVRPDRVYPLYGFHYSVHRAITRLTNLKL
                     FTWLCGDSSYIVPYLKALGYDLSRVEQTGSNFGTEVRHETPYLVTVGSGTMVADGLSVM
                     NADYSATSFRVSRTAIGGHNFLGNFIAYPVGGRTGENCLLATKVLVPLDGEIREGVGLL
                     GSPPFEIPRSVERDTRFDHLREGDELRRRLAAKNRFNLRSMGLFLFLRWLHTFALTVLG
                     FAAFDLYGHGDGMAGLLALAALPLAALVFTVLYYTLVERSMTRFRPLRPRLCSIYDPLF
                     WRQERLWKLRDTHIQVLSGTPYKNLVWRLLGVRIGRRVFDDGVVITERTLTAVGDDCTL
                     AAGSKIQAHSQEDGTYKSDHVTIGARCTLEVGAFVHYGVVLGEGAVLAPDSFLMKGEEV
                     PPHARWGGNPA"
     gene            17526..19991
                     /locus_tag="JIX56_RS09400"
                     /old_locus_tag="JIX56_09400"
     CDS             17526..19991
                     /NRPS_PKS="Domain: AMP-binding (235-639). E-value:
                     6.4e-101. Score: 329.8. Matches aSDomain:
                     nrpspksdomains_JIX56_RS09400_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (743-810). E-value: 5.2e-18. Score:
                     57.0. Matches aSDomain: nrpspksdomains_JIX56_RS09400_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999813.1"
                     /locus_tag="JIX56_RS09400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09400"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_257550793.1"
                     /sec_met_domain="AMP-binding (E-value: 5.2e-107, bitscore:
                     357.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.7e-06, bitscore:
                     27.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQSESGTAARKYWHEVLTAGGRTVVPRWSADPVKGVAAYEVALP
                     EGPLAASDGTAAVLAAHAKVLAALSGEHEVTTGWMEDGRLLPCRLTTAPGDTWRDLLGH
                     THRVTTELLTHADFPVDTLRRELGLAEPPFETVLDTSGGDGDLGEEVVLRVGLVYRDDG
                     PALRLRYRTEVLDEDGAARIAGYHVTALTRLAADPDAEHGRRSLVSHDELRFQLDGLAG
                     PYRELPDRRVHELFEQRVVAHPDAVAAVHGDRRWTYRELNSRANQLSRALLVRGLGREG
                     VVAVVTERNLDWMAAVLAVFKAGGAYLPVEPHFPAERIASTLARAGCELVLTEEGSTAT
                     LDEALPALPGVQRLLVGEAYDEAHPDSDLGMEIAPDRLAYIYFTSGSTGEPKGAMCEHA
                     GMLNHLQAKLDDLDIGEGDVVAQTAPQCFDISLWQLLAAPLVGGRTLLVEQEAILDVEQ
                     FVDRIADGRVNVLQVVPSYLEAVLAHLEQTPRELPDLRRVSVTGEALKKELAERWFATE
                     PGIPLVNAYGLTETSDDTNHEVMDRAPEGGRVPLGRPVRNVRVYVVDEHLSLVPLGAPG
                     EIVFSGVCVGRGYVNDPERTRRAFTTDPYLPGERLYRSGDHGRWRPDGKLEFLGRRDTQ
                     VKVRGFRIEIGEVENALLRVAGVRDGAVVVAKGAHLVAFHSGRPLAGEELRDRLAASLP
                     AYMVPSVFHWRESLPLTANGKIDRRTLTTLAEQLPAVPGESGGLPATPTEERLATAWAE
                     VLGVARSLIGRRDHFFDRGGTSLSAVKLAIALDRAVSPKDVTAYPVLSDLAGLIDTRAG
                     ANTVGRPTS"
     CDS_motif       17688..17735
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JIX56_RS09400_0001"
                     /evalue="4.90E-01"
                     /label="Cy4"
                     /locus_tag="JIX56_RS09400"
                     /protein_end="70"
                     /protein_start="54"
                     /score="3.8"
                     /tool="antismash"
                     /translation="TAAVLAAHAKVLAALS"
     CDS_motif       17853..17939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JIX56_RS09400_0002"
                     /evalue="8.80E-04"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="JIX56_RS09400"
                     /protein_end="138"
                     /protein_start="109"
                     /score="11.9"
                     /tool="antismash"
                     /translation="TELLTHADFPVDTLRRELGLAEPPFETVL"
     aSDomain        18231..19442
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JIX56_RS09400_AMP-binding.1"
                     /evalue="6.40E-101"
                     /label="JIX56_RS09400_AMP-binding.1"
                     /locus_tag="JIX56_RS09400"
                     /protein_end="639"
                     /protein_start="235"
                     /score="329.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEQRVVAHPDAVAAVHGDRRWTYRELNSRANQLSRALLVRGLGRE
                     GVVAVVTERNLDWMAAVLAVFKAGGAYLPVEPHFPAERIASTLARAGCELVLTEEGSTA
                     TLDEALPALPGVQRLLVGEAYDEAHPDSDLGMEIAPDRLAYIYFTSGSTGEPKGAMCEH
                     AGMLNHLQAKLDDLDIGEGDVVAQTAPQCFDISLWQLLAAPLVGGRTLLVEQEAILDVE
                     QFVDRIADGRVNVLQVVPSYLEAVLAHLEQTPRELPDLRRVSVTGEALKKELAERWFAT
                     EPGIPLVNAYGLTETSDDTNHEVMDRAPEGGRVPLGRPVRNVRVYVVDEHLSLVPLGAP
                     GEIVFSGVCVGRGYVNDPERTRRAFTTDPYLPGERLYRSGDHGRWRPDGKLEFLGRRDT
                     QVKVR"
     aSModule        18231..19955
                     /complete
                     /domains="nrpspksdomains_JIX56_RS09400_AMP-binding.1"
                     /domains="nrpspksdomains_JIX56_RS09400_PCP.1"
                     /locus_tags="JIX56_RS09400"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       18417..18455
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JIX56_RS09400_0003"
                     /evalue="1.90E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="JIX56_RS09400"
                     /protein_end="310"
                     /protein_start="297"
                     /score="14.8"
                     /tool="antismash"
                     /translation="LAVFKAGGAYLPV"
     CDS_motif       18660..18719
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JIX56_RS09400_0004"
                     /evalue="3.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="JIX56_RS09400"
                     /protein_end="398"
                     /protein_start="378"
                     /score="28.8"
                     /tool="antismash"
                     /translation="AYIYFTSGSTGEPKGAMCEH"
     CDS_motif       19236..19325
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JIX56_RS09400_0005"
                     /evalue="2.70E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="JIX56_RS09400"
                     /protein_end="600"
                     /protein_start="570"
                     /score="38.9"
                     /tool="antismash"
                     /translation="PLGAPGEIVFSGVCVGRGYVNDPERTRRAF"
     CDS_motif       19407..19472
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JIX56_RS09400_0006"
                     /evalue="3.40E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="JIX56_RS09400"
                     /protein_end="649"
                     /protein_start="627"
                     /score="35.1"
                     /tool="antismash"
                     /translation="FLGRRDTQVKVRGFRIEIGEVE"
     aSDomain        19755..19955
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JIX56_RS09400_PCP.1"
                     /evalue="5.20E-18"
                     /label="JIX56_RS09400_PCP.1"
                     /locus_tag="JIX56_RS09400"
                     /protein_end="810"
                     /protein_start="743"
                     /score="57.0"
                     /tool="antismash"
                     /translation="EERLATAWAEVLGVARSLIGRRDHFFDRGGTSLSAVKLAIALDRA
                     VSPKDVTAYPVLSDLAGLIDTR"
     gene            19988..21127
                     /locus_tag="JIX56_RS09405"
                     /old_locus_tag="JIX56_09405"
     CDS             19988..21127
                     /EC_number="1.14.11.-"
                     /GO_function="GO:0051213 - dioxygenase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: TauD (57-334). E-value: 3.5e-46. Score:
                     150.0. Matches aSDomain:
                     nrpspksdomains_JIX56_RS09405_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308349.1"
                     /locus_tag="JIX56_RS09405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09405"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_257538611.1"
                     /sec_met_domain="TauD (E-value: 5.5e-44, bitscore: 150.0,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFLSRRGAASRRRKNTGMAAPSSTALPLPDIESAAGRPPLLMVS
                     PADPAAHWVAGRREALRAAVAEHGSVLVRGLGLRDATEVGAVFRALADTLMSEKEAFAP
                     RRTYADGVYSSTAWPPNQPMCMHHELSYTVEFPGLMLFACLEAAERGGATGVADAEAVL
                     AALPPELTERFERDGWLLTRSYNDEIGASVAEAFGTDERTVVEAYCRAHAIEFAWQPDG
                     SLHTRQRRAAVLRHPMTGRRCWFNQIAFLNEWTMDAEVREYLVDMYGADGLPFNTRYGD
                     GDPIGEDAVRTLNEIYEAHTVREPWRPGDLLLVDNIRSAHSREPFEGPREVLVGLADPV
                     RPTDCATRDSDTQDSRSQDSRSQDPDSKDSDAKDEVSFR"
     aSDomain        20159..20989
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JIX56_RS09405_TauD.1"
                     /evalue="3.50E-46"
                     /label="JIX56_RS09405_TauD.1"
                     /locus_tag="JIX56_RS09405"
                     /protein_end="334"
                     /protein_start="57"
                     /score="150.0"
                     /tool="antismash"
                     /translation="REALRAAVAEHGSVLVRGLGLRDATEVGAVFRALADTLMSEKEAF
                     APRRTYADGVYSSTAWPPNQPMCMHHELSYTVEFPGLMLFACLEAAERGGATGVADAEA
                     VLAALPPELTERFERDGWLLTRSYNDEIGASVAEAFGTDERTVVEAYCRAHAIEFAWQP
                     DGSLHTRQRRAAVLRHPMTGRRCWFNQIAFLNEWTMDAEVREYLVDMYGADGLPFNTRY
                     GDGDPIGEDAVRTLNEIYEAHTVREPWRPGDLLLVDNIRSAHSREPFEGPREVLV"
     gene            21124..22164
                     /gene="sbnB"
                     /locus_tag="JIX56_RS09410"
                     /old_locus_tag="JIX56_09410"
     CDS             21124..22164
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sbnB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482025.1"
                     /locus_tag="JIX56_RS09410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09410"
                     /product="2,3-diaminopropionate biosynthesis protein SbnB"
                     /protein_id="WP_257538613.1"
                     /transl_table=11
                     /translation="MTEVPGFAVISGAQVQQALRGREGEIVDLVESAYLLHGAGDTGDT
                     VNPPSYFLRFPDRPSSRIIALPASLGGKFQVDGLKWISSFPENTASGLPRASAVLILND
                     HTTGYPFACLEASVISATRTAASAALAADRLSERRGAPRPARVGFLGTGLIARYIHTFL
                     EATGFAFEEVGVHDLSADSAAGFRGYLERSHASGRVTVHESAEDVIRASDLVVFATIAG
                     EPHIHEPKWFAHHPLVLHVSLRDLAPEVLLASANFVDDVEHCLKANTSPHLTEQLTGAR
                     DFLDGTLHDVLTGRATVPTDRPVIFSPFGLGVLDLAVGGYVHDEVARSGGLRVVDDFFH
                     ELRRHG"
     gene            22212..23222
                     /gene="sbnA"
                     /locus_tag="JIX56_RS09415"
                     /old_locus_tag="JIX56_09415"
     CDS             22212..23222
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sbnA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482024.1"
                     /locus_tag="JIX56_RS09415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09415"
                     /product="2,3-diaminopropionate biosynthesis protein SbnA"
                     /protein_id="WP_257538615.1"
                     /sec_met_domain="PALP (E-value: 3.1e-50, bitscore: 170.3,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVISVPTDFNEEELYVDLRQVVGHELFLKCEGFNFAGSIKLKAA
                     TEMVRAAERDGCLRPGSTLVESSSGNLGVALSMIAASRGYRFLCVTDSRCNPQTRRLIE
                     ALGSRVHVISEPDPHGGFLGARIAYVRALCAADPEYVWLDQYTNQANWRAHYRTTAPAI
                     ARQFPRLDVLFVGVGTSGTLMGCAQWFWERRRRVRIVAVDSVGSVAFGGAPGRRMIPGL
                     GTSVPPALLDPSCVDDVVRVEEIDTVRACHRMARRGFLFGGSTGTVVSGATDWLNRNGS
                     PDITAVAISPDLGERYLDTIYRPGWPLEQYGEGVLDPEDEFGTGELGTGELAAPV"
     gene            23346..24989
                     /locus_tag="JIX56_RS09420"
                     /old_locus_tag="JIX56_09420"
     CDS             23346..24989
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308264.1"
                     /locus_tag="JIX56_RS09420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09420"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_257538617.1"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 6.2e-16, bitscore:
                     57.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.6e-30, bitscore:
                     104.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAARTHEVTNQAPPLVDYDVFSADRALAEAVDRHLAPDLLDEARG
                     ELSGLGRTAGSVQVQEWGRLANENPPKLRTHDRYGNRIDEVEFHPSWHRLLGKGVSAGL
                     TAAWTRPGGHVRRAAGFVVWSQVEAGNGCPLSMTHAAVPALRTDPALAAEWEPRLTSPL
                     YDWDLRPADQKAGALFGMGMTEKQGGSDVRANTTGARPLAEEGTYELTGHKWFCSAPMS
                     DGFLVLAQAPGGLTCFLVPRVLADGSRNVFRIQRLKDKLGNRSNASAEVEFDGTWARRV
                     GDEGRGVRTIIEMVSATRLDCALGAASLMRQAVAQAVHHCAYREAFGGRLIDKPLMRNV
                     LADLALESEAATTLAMRLAAAYDAAEAGNETERSFLRLAVPAAKYWVTKRCTPTVVEAS
                     ECLGGNGYVEESGMPRLLRESPLNSIWEGAGNVQALDVLRALQREPGALDAYLREVGRA
                     RGADHRLDGAIKNLLTELADLDGIEARARRLVERLALVLQGALLVRYAPPAVADAFCAS
                     RLGGDWGTAFGTLPHTLDLASVVERARPVS"
     gene            25348..26667
                     /locus_tag="JIX56_RS09425"
                     /old_locus_tag="JIX56_09425"
     CDS             25348..26667
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308282.1"
                     /locus_tag="JIX56_RS09425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09425"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_257550794.1"
                     /transl_table=11
                     /translation="MEVARLTATDAARAARVLGEVRASALDGRRPKTAPRPAIRESWSR
                     MVHSGVDPDHDFRSDLLSQDEIERRRQSTRLRHVLPVLREGLLSLADTAQHIMMVADAD
                     ARVLWREGSTAVLRKADGQGLGIGADWREETIGTNGVGTPLVSRRPVQVFSAEHFVRAL
                     HPWTCTGAPITDPRDGRLLGAVDISGPLETLHPSTLALVDAVAKLAQARLRELHLTSLE
                     ELRAVAAPVLARIGGPAIAVDRDGWTAAVTGMPYTSRVALPKSLSPGRCRLSALGLCTV
                     EPLPAGWLIRPTADPAPASTTTHITLDVSHPRRWTVTVTGCAGSWTHELTPRHAELLYL
                     LALHRGGRSASALADDMFGDPARTVTVRAEMSRVRRYLGAFLDHRPYRFTERADVEVLL
                     PEAPLDLLPHSVAPGVVRARGAAPAGRPHPLPGERIMSPG"
     gene            26803..28206
                     /locus_tag="JIX56_RS09430"
                     /old_locus_tag="JIX56_09430"
     CDS             26803..28206
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482016.1"
                     /locus_tag="JIX56_RS09430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09430"
                     /product="hypothetical protein"
                     /protein_id="WP_257538627.1"
                     /transl_table=11
                     /translation="MKHRGRHRRRRRGRALRASLAGTALALTAAATLISTSQAAGGETP
                     GALSSIGSAGELRGLQLRETLTDETGLSILADEMGGGVGVDEVLESANHVMRDEDDCFD
                     SEKDNLPVEPAASRAYCWEPGDAVNDKWVPRSVTTSRNNQVIVSGWTSETGDGDTSADG
                     AGADRTNGDSTDGEGLTRVAFIDAKNPASLKYRWVLLVVPKADGQGFEGLRSRLGGMAW
                     YEDKLIVTARGPESGGRQDDSLYVFDMARFLRADVTDSDVIGKVGDGWSAHHYRYALPA
                     VATYSPAAGGGCDARDNDGVPCFGSLSLDRTSARPSLVASESFQPGREEPTRVWRYALD
                     TTADRTGLLTTTGRWSDAVATEAYETEATGVRGVLSHGGDWYIGQAGEGRDEHDTLWRQ
                     DQDGAKAAKCAADKSDEKSGLRTSACWGRHTASLSYSPETDEVWTLTDPIPERVLYAVK
                     LSDVDGTLG"
     gene            28378..28959
                     /locus_tag="JIX56_RS09435"
                     /old_locus_tag="JIX56_09435"
     CDS             28378..28959
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999820.1"
                     /locus_tag="JIX56_RS09435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09435"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_257538637.1"
                     /transl_table=11
                     /translation="MSSNPVTTWSLEQTSPSDLLPAAAPDGDDIRIVRSEVPSPEFSRF
                     LYASVGGDIHWIDRLSWSYDRWQEHLGRPGVETWVAYDRGTPAGYVELEPQDDGVVEIT
                     YFGLIPAFRGRRIGGHLLSCGTARAWDLAERWPGLPPTKRVWLHTCSLDGEHAMGNYLR
                     RGFTLFDTEVTEEADVPAPGPWPGATAPTP"
     misc_feature    28393..28408
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     misc_feature    complement(29015..29028)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.29"
                     /tool="antismash"
     misc_feature    29016..29029
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.86"
                     /tool="antismash"
     gene            29052..29135
                     /locus_tag="JIX56_RS47835"
     CDS             29052..29135
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042934.1"
                     /locus_tag="JIX56_RS47835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative leader peptide"
                     /protein_id="WP_309474722.1"
                     /transl_table=11
                     /translation="MSGTGIALVSRRHVDLGRMSSAICPVS"
     gene            29307..30998
                     /locus_tag="JIX56_RS09440"
                     /old_locus_tag="JIX56_09440"
     CDS             29307..30998
                     /EC_number="1.8.7.1"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0050311 - sulfite reductase (ferredoxin)
                     activity [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972818.1"
                     /locus_tag="JIX56_RS09440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09440"
                     /product="nitrite/sulfite reductase"
                     /protein_id="WP_257538648.1"
                     /transl_table=11
                     /translation="MAATPQNPATPRRKVSRHRGEGQWAAGHFTPLNGNEQFKKDDDGL
                     NVRTRIETIYSKRGFDSIDPNDLRGRMRWWGLYTQRKPGIDGGKTAILEPEELDDKYFM
                     LRVRIDGGRLTTQQLRVIGEISQEFARGTADITDRQNVQYHWIRVEDVPEIWDRLEAVG
                     LSTTEACGDTPRVIIGSPVAGIAADEIIDGTPAMDEIHRRIIGNPDFSNLPRKFKSAIS
                     GSPLLDVAHEINDIAFVGVRHPEHGPGFDLWVGGGLSTNPKIGQRLGAWVPLDEVADVY
                     EGVISIFRDYGYRRLRTRARLKFLLADWGTEKFRQVLEDEYLKRKLIDGPAPDQPVARW
                     RDHVGVHPQNDGRYYVGFAPRVGRVDGTTLTKIADLAEAHGSGRVRTTVEQKMIVLDVT
                     QEQVDSLVAGLEALDLTVHPSPFRRGTMACTGIEYCKLAIVETKARGSALIDELERRIP
                     EFDEPITININGCPNACARIQVADIGLKGQLVLNDAGEQVEGFQVHLGGALGLEAGFGR
                     KVRGLKVTSDELPDYVERVLKRFQEEREDGERFATWVTRASEEALS"
     gene            31303..32067
                     /locus_tag="JIX56_RS09445"
                     /old_locus_tag="JIX56_09445"
     CDS             31303..32067
                     /EC_number="1.8.4.8"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0004604 - phosphoadenylyl-sulfate
                     reductase (thioredoxin) activity [Evidence IEA]"
                     /GO_process="GO:0019379 - sulfate assimilation,
                     phosphoadenylyl sulfate reduction by
                     phosphoadenylyl-sulfate reductase (thioredoxin) [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482012.1"
                     /locus_tag="JIX56_RS09445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09445"
                     /product="phosphoadenylyl-sulfate reductase"
                     /protein_id="WP_257538650.1"
                     /transl_table=11
                     /translation="MTTVQADSDTAASFEDAADPEAAKRAELKALAEQAGRDLEDASAL
                     EILQWAVDTFGKRFCVTSSMEDAVVAHLASRARPDEGPVDVVFLDTGYHFPETIGTRDA
                     VEAVMDVNVLTITPRQTVAEQDAEYGPKLHDRDPDLCCFLRKVKPLEEGLARFDAWATG
                     LRRDESETRANTPVVGWDDKRGKVKISPIARWTQDDVDAYVAEHGVLTNPLLMDGYPSV
                     GCAPCTRRVAPGEDARAGRWAGNAKTECGLHL"
     gene            32118..32702
                     /gene="cysC"
                     /locus_tag="JIX56_RS09450"
                     /old_locus_tag="JIX56_09450"
     CDS             32118..32702
                     /EC_number="2.7.1.25"
                     /GO_function="GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cysC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999824.1"
                     /locus_tag="JIX56_RS09450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09450"
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_257550795.1"
                     /transl_table=11
                     /translation="MTDRVPVTNQENQVTTGATGATVWLTGLPSAGKTTIAYELAGRLR
                     EEGHLVEVLDGDEIREFLTADLGFSRADRHTNVQRIGFLADMLARNGVKALVPVIAPYA
                     DSREAVRKRHDASGAAYVEVHVATPVEVCSVRDVKGLYAKQAAGEISGLTGVDDPYEAP
                     ETPDLRIESQDQTVQESAALVHKLLTERGLA"
     gene            32699..33637
                     /gene="cysD"
                     /locus_tag="JIX56_RS09455"
                     /old_locus_tag="JIX56_09455"
     CDS             32699..33637
                     /EC_number="2.7.7.4"
                     /GO_function="GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA]"
                     /GO_process="GO:0019419 - sulfate reduction [Evidence IEA]"
                     /codon_start=1
                     /gene="cysD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996880.1"
                     /locus_tag="JIX56_RS09455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09455"
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="WP_257538652.1"
                     /transl_table=11
                     /translation="MTTTVAAVSEETGTPYTLSHLDSLESEAVHIFREVAGEFERPVIL
                     FSGGKDSIVMLHLALKAFAPAAIPFTLLHVDTGHNFPEVLEYRDRTVARHGLRLHVASV
                     QDYIDRGVLRERPDGTRNPLQTVPLTERIQAEKFDAVFGGGRRDEEKARAKERVFSLRD
                     EFSQWDPRRQRPELWNLYNGRHAPGEHVRVFPLSNWTELDVWQYIAREGIELPEIYFAH
                     EREVFMRAGMWLTAGEWGGPKDGETVEKRQVRYRTVGDMSCTGAVDSDATTLDAVITEI
                     AASRLTERGATRADDKMSEAAMEDRKREGYF"
     gene            33640..34968
                     /locus_tag="JIX56_RS09460"
                     /old_locus_tag="JIX56_09460"
     CDS             33640..34968
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007501014.1"
                     /locus_tag="JIX56_RS09460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_09460"
                     /product="GTP-binding protein"
                     /protein_id="WP_257538663.1"
                     /transl_table=11
                     /translation="MSTTTELTETTLLRFATAGSVDDGKSTLVGRLLHDSKSVLTDQLE
                     AVERASASRGQEGPDLALLTDGLRAEREQGITIDVAYRYFATAKRRFILADTPGHVQYT
                     RNMVTGASTAELTVILVDARNGVVEQTRRHAAIAALLRVPHVVLAVNKMDLVGYEETVF
                     AAIAEEFTAYASELGVPEITSIPISALAGDNVVEPSANMDWYGGPTFLEHLESVPVAHD
                     LAHCHARLPVQFVIRPQTAEHPDYRGYAGQIAAGTFRVGDSVTVLPSGRTTKVTGIDLL
                     GKPVAAAWTPQSVTLLLEDDIDISRGDLLVPTKDAPATTQDIEATVCHVADQPLTVGHR
                     VLLKHGTRTVKAIVKDIPSRLTLDDLSLHPHPGQLVANDIGRVKIRTAEALPVDSYADS
                     RRTGSFILIDPADGTTLTAGMVGESFASPEPVKDESEDDGWDF"
ORIGIN
        1 ctccgcgcgg tcctggacgt caccgaaccc gagccgctgc ccgccggctc ccccctctac
       61 aacctcccca acgtcttcct caccccgcac atcgccggtt cactcggcaa cgagctggag
      121 cgcctcggcc gtaccgtcgt cgaggagttg gagcgcctcg cctcgggcct gccaccggcc
      181 cacgaggtac gccacacgga cctggcccgg gtcgcctgaa ccgtgccggc acgccgccct
      241 ctccctccgc ggcgctctca cgtccgcacc ggaagccctc ccgctggcaa gggatgacag
      301 ggagacgtaa acgttttcac atgccgggcc gccgcgcgag ccgcttccgc gacggcccgt
      361 acgccgttcg gcgcgcctct gacctgggca gctccggtca cgctctcgtc accgatcagc
      421 gactctcggc aaccccgcgg acaatccggc gtaacaattt gccgtcgcgc tcttgcgtga
      481 gccgatcagg cgacctacgt ttcacagcaa ccgtttacta cacgttccgc aggggtcccg
      541 agacccgagc tgatggtccg cctcgctcgc cgtcgcccca ccgagccgcc cctcgctccc
      601 cccgcttccg cgatcgtcta cgtctcgaag gatgaccgta cgatgaactc caccagcccc
      661 cggagaaggt tcgcccgcgt tgccgtcgcg agtgtggcac tgacaggtct gctcgccgcg
      721 tgcggcggtt cggactccgg tgacgacagc tccggagcct ccggtccggt caccctcccc
      781 ttctggggct gggccaacgg ccaggagacc ctcgtcaagg cgttcaacgc ctcccacaag
      841 gacatccagc tcaagtacac caaggtcacc gaccagctga ccatgcagaa gcagctcagc
      901 aacgcggtga aggcgggcaa cgccccctgt ctgctgcaga acaccgccga gtatgtgacg
      961 acctgggtgt cgcagggcgc gctcgccgac atcaccgagt acgtcggggc gagcgaggac
     1021 aagttcaacg ccggcgcctg ggccggtgtc caggtgcagg gcaaggtcta cggcgtgccc
     1081 accagctcgg cgcccgcctt cacgatctac cgcacggacg tcttcaagaa gtacggcctc
     1141 gacgcgcccg cgacctggga cgacttcatc accgcgggca aggaactgaa gaagcacgac
     1201 atccacatca ccaactacgc cggtgaggac ccgagcaccc tggaggtgct ggccatgcag
     1261 gcgggcgccc actggtacgc gatcgacggc gactcctgga aggtgaactt ccaggacgag
     1321 ggcagcctca aggccgccga cgtgatccag cagatcatcg acaacgacct caactccaag
     1381 ctctccttcg ccgactacgc ggccgtgcag cgcaactacg acaagggcgg cacggccacg
     1441 cggcagatct cgacctggca gatgtccggc atggtgcaga acttcaccga ctctttcggc
     1501 gactgggcgc tcacaccgtg gccgacgtac aagggcgagg cggcgaagac cccggccggc
     1561 accaaccaga gcggtggcat gaacctggtc accgagcagt gcgagtacaa gaagcaggcg
     1621 gccgaggcgg cgctgtggct gtccaccgac accgacgcgg tgaagtcgat ggcgagcccg
     1681 gagaccggca gcggtgtcat gccggctctg gccgacagtg acgcgtacgt cgccgaggcg
     1741 atctccgaga agctgctcgg tgaccactac gagccgggca agaaggtcgt cacggacagt
     1801 ctgggcaccg tgaccaccga ctgggtctac ggcccgaact ggaccgcgat gttcaccgag
     1861 ctgcagagcg agtggggcaa ggtcgtcagc aaggaacaga aggtcaccga cctgctcgcg
     1921 cacatgcagg agtggacggt caaggacctg aagtcccgcg gtatcaacgt caagggctaa
     1981 aggcatcttt cgatgattcg ctcccagcgc tggaagggtg ccgcgttcac ggtgcccttc
     2041 cagctcggat tcgtcttcct ctatctgctc cccatcgggt acgcggtgta cgagtcgctg
     2101 ttccaggaga agcagtccgg gctcggcctc ggcggtgcga cgcgggagta ctccgggttc
     2161 gacaactacc ggctcgggct gaccgactcg gcgttcatgg gctccatcct gcgggtggtg
     2221 ctgttcgcct gcgtgcagat accgttcatg ctgctggtca gcctggtcct ggcactgttc
     2281 ctggacgcgc tcacctcgaa ggcagcgaac cggttccgga tcgtgctgct gctcccgtac
     2341 atgatcccgg gcgtggtcgc ggcgatcgtg tggatcaacc tgtacagccc cgaggtcggc
     2401 ccgctgaccc cggtcggcga cttcttcggg ttcgactgga acttcttctc gccctccatg
     2461 gtgtggccgt ccatcggcaa cctgctcacc tggcacggca tcggctacaa catggtgatc
     2521 atctactcgg cgctccaggg cgtgccccgc gagctgttcg aggccgcccg cctcgacggc
     2581 gcctccgagg cccgtatcgc gctgaacatc aagatcccgt tcgtacgcgg tgccctggtg
     2641 ctgaccgggc tgctctccat catccagatg ctgcagatct tcaacgagcc ggcgctgttc
     2701 cggagaatca ccccggagac cgtcgacgac agcttcaccc cgatcatgat catctacaac
     2761 caggcgttca acgcgggcaa ctaccactac gccgccgccc tgtcagtgct cctcgccctg
     2821 atcctcggcg tcgcctcctt cctcttcttc cggctgactt cgaaggaggt cgactgatgg
     2881 ccacgacgac gaccaccggc tcccccgaga agtccgggac atccgggacg tcgggggtcc
     2941 cgcccgtgcg gcgcatcacc cgcgcggaca ccgcctcgcg cgggcgcggc ggccagcggt
     3001 tcattctgct cggtctgatc ctggccagcg cctacagcct gttccccgtg tggtggctga
     3061 tcgtcgcctc caccaaggac cgggtcgggc tgtaccagag caacggcatg tggttctccg
     3121 acatacacct gtgggacaac ctgcgtcagc tgttcacgta cggggacggc atcttcctgc
     3181 gctggaccgc caactcgttc ctgtacgccg gtgtcggctc cctcggcggc accctcatcg
     3241 ccctggcaac cggttacggc ctggcccgtt tcgacttccc cggccggggt gtggtgttcg
     3301 cgtgcgtggt gggctcgttc ctgatcccga tcgccctgct cacgctgccg ctgtacctga
     3361 tgttctcgaa gatcggcctg gtcgacaccc cctgggcgat gctgatcccc tgcctcatca
     3421 accccttcag cgtgtatctg gcgaaggtct acaccgaggc gacgatcccc ttcgaactcc
     3481 tggaggcggc ccggatcgac ggcgccggtg agctgcggat cttcttcagc atcgtgctgc
     3541 ggatgatgac cacgggcggc gcgacggtct tcctgctggc cttcgtcaac acctggaacg
     3601 ccttcttcct ccccctcacc gtcctgcgcg gcgaggagaa ctggaccctc aacctcggcc
     3661 tctacaactg gaccggtaaa agcctcgaat ccggcatcga cctgacgagt ctcgtcctga
     3721 ccggcgccct gctctccatc gtgccgctgg cgatcatgat gaccgcgatg cgccgctact
     3781 ggcggtccgg tgtgacgctg ggggcgctga agtgacacgt ccggtgcctg ctcgaggggc
     3841 cggtccggtg cctgctcgag tgaccgtcag tctggaagca ccgggagttc gctcatgacc
     3901 gtggcccaca accccgtcat ccgtggcttc gcccccgatc cctccctcat cagggtcggc
     3961 gagtggtact acgtggcgac cagttcgttc gagtggttcc cgacgattcc cttgcaccgg
     4021 tccagggatc tggcgcactg ggagtacgcc ggccatgtgc gcggcgcggc cccgggcggc
     4081 tcactggccg gcgtccccga ctcgggcggc gtctgggcgc cttccctgag ctgggacggc
     4141 gaacgcttct gggtggtcta cacgatcgtg cggtcggtcg gcacgcggta cttcgacctg
     4201 gacacatacg tcagcacggc cgcggcggtg gacggcgagt ggaccgctcc aaggcgggtc
     4261 gcgagccatg gcttcgaccc cgcgctgttc caccacgagg gccggctctg gctgctcaac
     4321 atgcagagcg accaccgccc cggcggcaaa cggttcgccg gtatcgtcct gacggaattg
     4381 gaccgctcca ctctgcgccc cctcggcgac acccacctcc tcctccagca cgacaagctg
     4441 atcgagggcc ccaagctcct ggtccacgac ggctggttcc acctggtgct ggccgagggc
     4501 ggcaccggtt tcgagcacgg ggtgcgggtc gcgcgcagcc gctcattgac cggcccgtac
     4561 gagctggacg atctgcccct gctgacgacc cgggacgacc cgaaggtgcc gctgcagaag
     4621 gccgggcacg ccgagctggt cgagacgccg accggcgagt ggttcctgag ccacctcacc
     4681 gcccgccccc tgcacaccga ccagggcatg cgctgcccgc tgggacggga gaccgccgtc
     4741 caggcggtgg cctgggacgc ggaggggtgg ccgaggctgc ggcagggggg ttggcatcct
     4801 gcggtcgagg tggaggtgcc gaccgtgcct ggggcctccg gcgagtccac gtccacgtcc
     4861 acgtccacgt ccgcgccggt cgtacgcggg gacacgctgt cctggccgtg gagcagtctg
     4921 cgcgcggagc cggacgcgtc ctgggtcgac gcgacggccc gtcccggctg gatccggctg
     4981 cgcggacggc aggggcccga atcgctgtgg gaccagagcc tgttggccca gcgcgtcacc
     5041 gagcaccggg cggaggtgga ggtcaccgtg gaggcccggc cgcgcacctt cggcgaggcc
     5101 gcggggctga ccctccgcta caacgccgcc tcctacctca ccctcgacct gacctgggcc
     5161 gaacccgagg gcgagccgca gcgcggccag cagtggcggg gcgagggccg caccgtactc
     5221 agcctcgtcg aacgtgacga tgagggcgcg cggcaggtgg ccgaggtcga ggtcgaggcg
     5281 gggcggccgg tcactctggg ggcgagtgtc gacggcgccg aggcccgctt ctggtatctg
     5341 cgcgacgagg tacgtacgcc gattggaccg gtcctggact tcagccggct ctccgacgac
     5401 tacgggtcca agctgcgctt cacgggcgcc ttcgccggca tccacgccca ggacctcgtc
     5461 ggcgcggcct tcacggcgga cttcggcggg ttccggctgg tgtgcggcga ggagtgaggg
     5521 caccgccccg ggtgcgggtc cgccccgcag ggctctggct ctggctctgg ctctgtgcag
     5581 gcaacgctgc ggggcaatac gcctggggtc tgtcggtgaa gtgccggtca tggctactcg
     5641 ttgaggactg cgaccagaac ccctgggggc aagcccccgt gaacagacgc cggttgcgcc
     5701 cccagccctc cggcccccga cggccctcgg ccaagcaccc atccgcgccc cttgttcgag
     5761 gtttcgaaag ttttggcttg ggcggtcctt tgattccccg ctccttcccg ccgtgttgag
     5821 ttggccttac cgtaggaagc gcttgctacg tggcgggtgg ttccgccgcg cgagcgaggc
     5881 tgttcgaaaa tttcaccggc cctcgggacg gggccctgag aggtggagtc gcgatggtgc
     5941 gtggcgggag cgcgacggcc gggccgacgc tggcggtggt ggcgcgcgag gccggggtct
     6001 ccgtaccgac ggcctcgaag gtggtcaacg gccgggagga cgtggccccg gagaccaggc
     6061 gccgggtcac cgaggcgttg gaccggctcg gttacgtccg cagaccccgg ttcgaggcgt
     6121 cgaaaccgcc gcgcatggtc gacctggtgg tgcactcgct ggagagttcc tggtcgggcg
     6181 cggtactgca cggcgtggaa caggcggccc acgacgccgg cctggaggtc gtggtctcgg
     6241 ccggtctgac ccgcacccgg ggcgcccgcc cggaacgcgg ctggttcgac aagctgaccg
     6301 cccggggctc ggccggcgtg ctgttcaacc tggccgaact gtcccccgcc cagtactcct
     6361 ggctcaccca gcaccgcatc ccgttcgtcc tgatcgaccc ggtcctcgaa ccgccgcccg
     6421 gcgtggtgtc ggtgggcgcg gccaactggc agggcgggac caccgccacc gagcatctgc
     6481 tggccctggg gcacgagcgg atcgccgtga tcgccgggta ccggcggaag atgtgcagca
     6541 gcgcacgggt ggcgggctac cgctcggcgc tgatggccgc ggggatcccg taccggtcgg
     6601 agtacgtccg ctacggcaac ttcatggaga ccgcctcccg ccaccgtatg ctccagctgc
     6661 tcgacctccc cgaaccgccg accgccgtct tcgtctgctc ggacaagatg gccctcggcg
     6721 cgtacgaggc gctggccgag cgggggctgc gggtgccgga cgacatcagt gtggtcggtt
     6781 tcgacgacct gcccgaggcc cggtgggcga atcccggcct gaccaccgtg cgccagcccc
     6841 tctccgagat ggcctcgacc gcgctgcggc tgctggtgcg gatgatggag ggcgaccaac
     6901 cggaggggac gcgcaccgag ttgtcgacgc ggctggtgga gcgggcgagc acgggggtgc
     6961 tgcgctcggc ctgaaggggg agtgggatcg tgtcggggtt cggacgaaat ggttgcggag
     7021 cacctgagtt cgggtgaacg gtgggcgtcg tcggaccgta cgcatagtga tgggcgtacg
     7081 ggtgtgatgg cggtgccgcc gtccccggcc ccctccgctc caccagcact gagctccaca
     7141 tgctccacag ggaaggacct tcgggttgtc gcacatacgc tctccgcagc ttccgggacc
     7201 gacaccggca ccggacgacg acacggcccc ggaggacgcg gcccctccgg agcgggaagc
     7261 ggttacggag accaaggcgg aggccgagga gccggcggag ccggatacgg ggaaacccga
     7321 gcctgaggcc aagccggccc ccgagcccga gcccgaggcc gagccggcag ccgcacccga
     7381 ccctgcggcc gagccggccc ccgagtccga ggccgagtcg gcagccgcac ccgaccccga
     7441 ggccgagtcg gcccccgcac ccgatcctga gcccgcatcc acgtcggccc ccgcccccgt
     7501 cgcaccaccc tccggctggc gcaccaagca cccccgggcc gcgcgtgccg tcgcctgggc
     7561 cgtgaccgga ctggccgtcg ctctcgtcat gttcgtgctg ctggtgccga acgacgtgac
     7621 caacatcgag gtcggccgtt tcctgcggat cccggcggag ggaatcctcg tggcggcgct
     7681 gctgctggtg ctgccgccga gggcgcggcg cgtggcggtg gtggtcgtcg gggtggtgct
     7741 cgggctgctg atgatcgtca aggtgctgga catggggtcg tactggaccc tggaccgccc
     7801 gttcgacctg gtgctggact ggatcctgct ggacgacgca cagtcgttca tgaaggactc
     7861 gctgggcggc gcggtcgcgc gggttgccac gatcggggtg atcgcgctgg cgctcgcgct
     7921 gccggcgctg atgacactcg cagtcgtgcg gatcagccgg ctgatggtgc gccaccggca
     7981 cacggcgagc cgtacgctgc tggtcctcgg aaccgcatgg atcacctgtt cgacgttgac
     8041 gctggaggtc gccgacacac cggtggcctc gcacagcgcg gcgaccctcg tggagaaccg
     8101 gatcgaggcg gtgagcgacg gtctgaagga cggggaggcg ttcgagaagc aggcggcggt
     8161 cgacgccttc gccgacgtac cgccggacca gttgctgacg gggttgcgcg gcaaggacgt
     8221 actgatcacg ttcatcgaga gctacggccg ctccgcgatc gacgacccgc agatgggcga
     8281 gccgctcggt gagacgctca cgcagaagac gaaggagctg gaggaggccg ggtacgcgtc
     8341 gcggagcggc tggctgcgct cccccatcac gggcgccggc agctggctcg gccactccac
     8401 gttcctgtcc ggtctgtgga tcaagaacca gtcgcgttac gccaacctcg tcgcgagcga
     8461 ccgtctcacc ctcaccgagg cgttccgccg caccggcgcc tggcgcacgg tcggcatcgt
     8521 gccgggcacc cagatggcct ggccggaggg caagtacttc ggcctggacc acatctacga
     8581 ctccgaccaa ctcggttaca aaggcccgaa gttcagctgg tcgacgatgc ccgaccagta
     8641 cacgctgaag gcgttcgagg agctggagca cggcaagcgg gaccgtgagc cgatgatggc
     8701 ggagatcatc ctgacttcca gccacaaccc gtgggcgccc atcccgagca cgatccccga
     8761 ggagcggatc ggcgacggct cggtctacca ctcgctccag aaggcggagg gcaaggaccc
     8821 caaggaggtc tggaaggacc cctcggacgt ccgcgacgag taccgcaagt ccatccagta
     8881 ctcggtgacc agcctcgtcg actatgtcgc gaagtacggc tcgaaggaca ccgtcctggt
     8941 cttcctcggc gaccaccagc ccaacaagac ggtcaccggt gccaatccca gccatgacgt
     9001 gccggtctcg atcgtcgccc aggaccccga ggtactggag aagatcgccg actgggactg
     9061 gacggacggc ctcaagcccg ccgacgacac cccggtgtgg cggatggaca agttccgcga
     9121 ccgcttcatg acggcgttcg gcccgcaggg cgccgggaac cgttcctaaa gactgagcgg
     9181 gagtgagtcc tgttgccagg actcatgctc agccgaacaa cccgaacggt attgggtgtt
     9241 ctggtcgccc gctttcgctc cgcgtccggc gcgcacggat cgtgtccgtg gtccggggat
     9301 gcgggggcgg gttccctcac gcccgggaat gcctggtcgg gcctggacgg tccgatgccc
     9361 ctgctcatcg ctccggtgag cagggggcgg tgccgtccgt cgccggatcg ggtgtccctg
     9421 ggcgcgcctg ccgatcgcca cggcggccgc gccgtggcga gtggtggtgc gggtggtgcg
     9481 ggtgaggggt ttctgccagt gctgggcgcc ccagcggctg gtgtaggccg ggtcccctag
     9541 tcgcggctgt ggtccgcccg ggccagctcg gccccgggcg gaccacagcc gcgtcaccgc
     9601 ctcactgcgg cggcttcaac tggggacggc tcacggggtc gcacggcttg acctggccct
     9661 tgaagaacat gtaccggaaa gcttgggccg ttctcatgtc cgaccccttc ggaccggacc
     9721 cgggcaggta ctcctcgacc acatacgcgt ccgcatgcgt catgacgtac tggtagcccc
     9781 ccttgccgtc gccggtcttc tgctgattca ggggcgttcc ccgatcgagc cggcacgtct
     9841 tgcccgcggg aatcttgtcg acgatcgcgg tgaagccggc ggcccggatc tcgcgtgcca
     9901 gccgctcgaa gtgctggggg tccccccacc agtcgaggtc gcggacggag atggtcagcg
     9961 tgccgtccgg gttcttctcc accgcgtagg cgggagtctc cgtcccgccc ggcaccggca
    10021 ccgccaccgc cacgccggcc acgatcgacg ctgcggccag cccccacgcg aaccgctttc
    10081 gcacgcggcg cccgtgctcg cgcccgccgg tgcgttcttt ttccatcgtc cgccaactgc
    10141 gcatcaggtg ttcctcacgc tggatccgtc ggccggcggg gaggtcccgc tcggccggca
    10201 cggccagcag ccggcgcagt tctcggacgt cgtcgtcccg gtctccgtcc cagctcaccg
    10261 cagtcccctt ccgttgtccc cgctcggccg gaccgcctcg tggcggtcac ctgtctgctg
    10321 ccgtctcgcg gccgcaggtt ccgtgtcacc gtcaagattt ttctgcgtca gtttctgcag
    10381 ccgaccacgc gcccgggaca gccgggagcg gacggtgccc accggcaccc ccagcgcctc
    10441 ggcggtcgcg gcgtagtcca gcccggccca cacgcacagc gccagcacct cgcggtccgg
    10501 ccgcgacaac tggtccagcg ccttgcgcag cgcggcgatc cgctcctggt cctcgagccg
    10561 gccgaccacc tcgtcggcga agtcgggcaa caggccgggc gggggcattc gctccatcag
    10621 ggcccggtgc cgccgggccg tgcgtcttcg gtggtgcacg acgtacgtgg cgatccccag
    10681 cagccacggc agcaggcttc cgccgtgcgg gtcgaccttc tcccgtatcc gccaggcttc
    10741 gaggaacacc agtgagacgc agtcctcagc gaccgaccag tcgccggtca ggcggaagca
    10801 gtggttgtac accgcccgcc cgtgctcgcg gaacagcacc ctgaaggagt cctcgtcgcc
    10861 cgctcggacg cgggcccgga atagtggctc catacctggt tctgccattc cgccaccccc
    10921 gagttccctg tgatgcgcgt cacgggaccg gaatgcggtc ctgaagcagg gtgcggtcct
    10981 ggtcggagcg ggcggccggc gtttcgccgg aggagatgcg ggccgccggc atgggccgac
    11041 tctcttcggg gcccggccgc gtcgaacggc cgcgcccgac tggaccgttc cagtcctggc
    11101 cggggctcag cccgacgtgc ccacctcgtt gttcggtgcg ccgtcgcccg ccgggggcag
    11161 gtcgccgcgt tggatcggca tgccgtcgtg cgggggcggg ggcttgtcgt ggtggcgggg
    11221 cgggaggagg aaggcgagtt cggcgtcggt ggggcggtgc gcggcgaggg ccgccgcgcg
    11281 caggacgtcg cggtcgaccg cggccgtggc ggcgctgatc cggacgacat ggccgtcctc
    11341 cggtacggcg tactcgtgct gtcccgccga ggtccggtac caggtgtccc cgtcgcgctc
    11401 gcagccgacg gacgtacccg tgccctggcc gagcgggtgc tcggggcagt tctgggcgtt
    11461 catcgtgccg tggtcgacga ggagcaggag ttgggcgctg ttcttccggg accagtagac
    11521 ggcggagaag ccgtcgtcgc cgtacacgcc gaccgactgc cgggccagca tgaatccggg
    11581 cgactcggtg acatggacga gccccggcgc gatgcccagc gcctcggcgc gggcgtgcag
    11641 ctcggcgggg tcgggggcag gcatcagggg ctcccggccc gcggccacga ccttctcggt
    11701 cccgcaggcc gtgagcagca acggcagcaa cgccaggggc agcagaacac gtgcggtacg
    11761 gaacatgccc tccatcctgc cgcacagttg ttccacaggt gagccaaaga gtccgttccc
    11821 gcgagagcgc ttactcacat ggttccctcg cgccgcggca ggcgtcggcg tgcgggtctc
    11881 gcgaggagcg tgaggtgtcc gattccttca agaccggccg gcgccggccc gcctacggtg
    11941 accgtatgac tccacgactc gatgcgatcg gcatggtggc ctcggacatg gccgcctccg
    12001 tcaccttcta ccgccggctc ggtttcgcct tccccgaggg cgccgagaac cagccgcacg
    12061 ccgaggccca gttgcccggc ggtctgcggc tgatgctcga caccgaggag accgtccgtt
    12121 ccttcttccc ccagtaccgt ccggggacgg gcggcggcgc cgggctcgcg ctcctgtgcg
    12181 acagtcccgc cgaagtcgac gcggtgtacg aggagttggt gaacgccggg taccagggcg
    12241 agctgaagcc gtgggacgcg gtgtggggcc agcggtacgc cgtgatccag gaccccgacg
    12301 ggaacggggt cgacctcttc gcgccactgc cgacgtccgc ccccgagtag ccgacccgcc
    12361 gccgcaaccg acaccggcac cggcaccggc accgggcacc gggcaccggg caccgggcac
    12421 ccgctatcgt ccgccgagca gttcgccgag cggcagcccc gccaactccc gtacatcacg
    12481 cgcgagatgt gcctgatcgg cgtacccggt ccgggccgcc gtctcggcga agggcacccc
    12541 gtcccgggcg agcgcgagcg cccttcgcag ccgtagcacc cgcgccagcg tcttgggccc
    12601 gtacccgaac gcggcgagcg acctgcggtg caactgccgt accccgagcc cgagttcgtc
    12661 ggcggtcgcg gcgaccggcc gccccgcgtc cagcgcgacg acgatccgcc gcagcagcgg
    12721 atcgggccgc cccccatcgg ccgcccgctc cagggccacc tcttcgagcc cgctcgccgg
    12781 gtcggccgcc gcgttcaccc gggcggtgag ccgccgtacg agcgccggtg accacagctc
    12841 ggcaagctcc acgcgccggt cacgcagctc atgcgcgggc acacccagat aggcgggcgc
    12901 ggtgccgggg tagaagcgga ggcccgccca gctgctgggc gggccttcgg tgacgtacgc
    12961 cgtcgtatcg ggcccggcga ccaacagccg cccgtcgttc cacagcagat ccatgcaccc
    13021 gtccggcaga atgcgcccgg ccccgggctc gcccgaacca ctcggcgtgt tcgtccacac
    13081 gacggccccg cccagccgag acgccctttc cgcatacaca cgaaaaggct acgcctgtga
    13141 acaaaggggc tccccagcat gccccggggc gcgcggggac cgaacgagca accgcgcact
    13201 acccccgggc accgccacgc ctcggaggtg agcgtgagcg ccgttggagg tgcgggtgct
    13261 ctgcggaccg cggaccgtcc gtggctgatc gcgcagttcc ccgcgcccct tcagggcgct
    13321 agtcgtcccc cttcttcaca ggtgaccgca gccgtgacgt cacgtcctcc ggcggcagga
    13381 agcgtgacca ccgctccggg aactcggacg gcatgtccgg gtcctcgggg tcgtgggagc
    13441 gggcggcggc ggcgcgggcg acgtactcgg cggcctgttc ctcgcggagg cgctcgttgg
    13501 cggcgcgggc ggcggcggtg gccgcggcgg gccagacgcg gtcgatggcg gcgttgacgg
    13561 cggcgccgac cagtacggcg aaggcgctca caccgatcca gaggaggacg gcgacggcgg
    13621 cggccaggga gccgtagatc gtcgccccct cgaccgtgct ggtgaggtag atgcggagca
    13681 ggaagctgcc gaggacccac atgccgaggg ccatgaggga gcccgggacg tcctcgaccc
    13741 agggggaacg gaccggaacc gagacgtggt agagcgtcgt caggaagacg atggacagga
    13801 cgatcacgac gggccagtag aggacctgga cgacggtcgc cgaccacggg acgatccgga
    13861 cgacggcgtc ggggccggcg accatcagcg gcagggcgac cgacccgatc agcagggcca
    13921 cgatgaagag caggaacgcc atgaggcggg tcttgacgat gccgcggacg ccgtcgaggc
    13981 cgtacatgac ggtgatggtg tcgatgaaga cgttcaccgc gcgggacccg gaccacaggg
    14041 cgaagaggaa ccctatcgag atgacgtcgg ggcggccgcc cctcatcacg tcgtccagga
    14101 tgggctgcgc gatctcggcg acgcccttgt cggacaggac ggtgcgcgag gcctccagga
    14161 ggttgagctc caggctggcg atggtgtcgg cgccggtcca gtcgtcgacg tagccgagca
    14221 ggccgatcat gctgagcagc agcggaggca cggagagcag cgtgaagaac gccgcctcgg
    14281 ccgcgaggcc caggatgcgg tactcgatgc aggagttgac ggtgtccttc aggagcagcc
    14341 aggcggtcct gcgcttggag acgttccggt agagggcacg cgcgcggtgg agacgcccat
    14401 gggggctctc gggtggtggg ggtgactgac ttgctggctg cacgccctaa aggtatccgg
    14461 ccgggcgtgc cgccctcacc tcccggtgcc gcccgccgcg gcggggtccg cgtgcggcgc
    14521 aggcttccct ccggtcgcgt cacggggcag caaacaaaag gaaacccagc agaaaacaaa
    14581 ggtgattccg aatctccttt tctgtcatga acgtgctggc cgaatcagtg agggaccaga
    14641 agtggaacgt tcgggcacgc ttgtacccgc tttttggaaa gttccccgct gaagccttgg
    14701 gtcgaaccgg gtccgacggg ccggaagaga tcggaaaagg ggtgggaaag cgtcaattac
    14761 ccgacccgcc ttgacccgtt cccgaacgta ccgaaagaat ccggattgca ttccgttgcg
    14821 cccacctgga ccaggtaccg gcgcaacgcg caccggggga ttcacgcagg ctccgaccag
    14881 gcctgatcaa ttccgcccca cccgtcaccg ctctccatcc cctctccttc tgtcattccg
    14941 cgcgccgtcc cgttcacccc cgggcgcctt ccctcgcaat acctgtcgcg gagaaattca
    15001 atgacattgc cagtgccacg acacgtggtg gaaaaaccgg gtgaggtcca ggcggccgag
    15061 ccggacgcgg cggaatcgta caccgccacc gagcgactcc tcgccgaact tctggccggc
    15121 gtcgcacgta tcgaacatgt gcccgcagaa agccatttct tcgacgactt gggcgccaac
    15181 tccctgacga tggcccattt ctgtgcccgc gtcaggaagc accccgatct gccgtcggtg
    15241 tccatacggg acgtctacgg ccacccgacc atccgcggcc tcgcggccgc gctcaccgag
    15301 gcaccgccac cgccggccgc cccgccggta cccgctgagg tcacaccacc gggcaacacg
    15361 ttccggtacg tcctgtgcgg ggcgctgcag ttgctcctct tcgccgcgta ctccctgctg
    15421 gccacgtccg gatacgtact ggggtacgag tgggtggcgg acgcctcggg catcgtcgcg
    15481 gtctatctcc ggtcggcgct cttcggcgcg ctcgccttcc tcgccctgtg caccctgccg
    15541 gtcgtcgcca agtggctgct gatcgggcgg tggaagcccg gggagttccc cgtgtggggt
    15601 ccggcgtatc tacggttctg gatcgtcaag gcgctgctgc gcaccagccc gatgatcctg
    15661 ttcgtcggca acccgctgta cgtgctgtac ctgcgggccc tcggcgcccg gatcggcccg
    15721 ggcgtcacga tcctcagccg caccctcccg gtctgcaccg atctgctgac gatcggcgcg
    15781 ggcacggtga tccgcaagga atccttcttc ctctgctacc gggcgcgcgc cgggcggatc
    15841 cgcaccggcc cggtgaccct cggccgggac gtcttcgtcg gcgagcacac cgtgctcgac
    15901 atcgacaccg ccctgggcga cggctcccag ctcggccact cctccgcact gcgcgccggc
    15961 gaggcggtcc cggccgggca gagctggcac ggctccccgg ctcggcgcac ggacgtggac
    16021 cacatccggg tcgccccggc cgactgcggc aggctccggc gggccggata cggatgcgcc
    16081 gccctgctcc agacactgct gctgtatgtg ccgctgaccc tcggcggcgc gtatctgctg
    16141 ctcaccgccg cgccctcgct ggacaccctg ctcgacccgg cgtcgcggca catcgcgtcg
    16201 gcgcgcttct acctcgaggc actggccctg tcgctcgtgc tgttcgccgg ttccctcgtc
    16261 gtcgcagccg tcgtcgtgtt cgtcgtgccc cgactgctgc gcccgctggt ccgcccggac
    16321 cgcgtctacc cgctgtacgg cttccactac tccgtgcacc gcgcgatcac ccggctgacc
    16381 aacctcaagc tcttcacgtg gctgtgcggc gacagctcct acatcgtccc gtacctcaag
    16441 gccctcggat acgacctctc gcgcgtcgag cagaccgggt cgaacttcgg cacggaggtg
    16501 cggcacgaga cgccgtacct ggtgacggtc ggcagcggca cgatggtcgc ggacggtctc
    16561 tcggtcatga acgcggacta ctccgccacg tcgttccggg tgtcccggac ggcgatcggc
    16621 gggcacaact tcctgggcaa cttcatcgcc tacccggtcg gtggccggac cggcgagaac
    16681 tgtctgctgg ccacgaaggt gctggtcccg ctcgacggcg agatccgcga gggggtcggg
    16741 ctgctcggct cgccgccctt cgagatcccc cgctcggtgg agcgcgacac ccgcttcgac
    16801 catctgcgcg agggtgacga actgcgccgc cggctcgccg cgaagaaccg cttcaacctg
    16861 cgctcgatgg ggctgttcct gttcctgcgc tggctgcaca ccttcgcgct caccgtcctc
    16921 ggcttcgcgg ccttcgacct gtacgggcac ggggacggca tggcgggact gctcgcgctc
    16981 gccgcgctgc ccctggcggc gctcgtgttc accgtcctgt actacacgct ggtggaacgg
    17041 tccatgaccc gcttccggcc gctgcggccg cggttgtgct ccatctacga cccgctcttc
    17101 tggcggcagg agcggctgtg gaagctgcgg gacacacaca tacaggtgct cagcggcact
    17161 ccgtacaaga acctcgtctg gcggctgctg ggggtccgga tcggacgacg ggtcttcgac
    17221 gacggggtgg tcatcaccga gcggacgctg acggccgtcg gggacgactg cacgctggcc
    17281 gcgggcagca agatccaggc gcattcgcag gaggacggca cctacaagtc cgaccacgtc
    17341 acgatcggcg cgcgctgcac gctggaggtc ggagcgttcg tccactacgg cgtggtgctg
    17401 ggcgaggggg ccgtgctcgc gccggactcc ttcctgatga agggcgagga ggtgccgccg
    17461 cacgcgcgct ggggcgggaa cccggctacg gaaaccaccg gagaacggtg aatcgggggg
    17521 aaatgatgga tcagtcggag tcgggcaccg ctgcccggaa gtactggcac gaggtgctca
    17581 ccgccggggg gcggaccgtg gttccgcggt ggagcgccga tccggtgaag ggcgtcgccg
    17641 cctacgaagt ggcgcttccg gaggggccgt tggccgcttc ggacggtacg gccgcagtgc
    17701 tcgccgccca tgccaaggtg ctcgccgcgt tgtcgggcga gcacgaggtc accaccggct
    17761 ggatggagga cggccggctg ctgccgtgcc ggctcacgac cgcgcccggc gacacctggc
    17821 gcgacctgct ggggcacacc caccgcgtca ccacggagct gctcacgcac gcggacttcc
    17881 cggtcgacac cctgcggcgc gaactcggcc tcgccgagcc gccgttcgag accgtgctcg
    17941 acacgagcgg aggcgacggc gacctcggcg aggaggtggt cctgcgggtg gggctggtgt
    18001 atcgcgacga cgggcccgcg ctgcggctgc ggtaccgcac cgaggtgctc gacgaggacg
    18061 gcgcggcccg gatcgccggg taccacgtca ccgcgctcac ccggctggcc gccgatccgg
    18121 acgccgagca cgggcggcgc agcctggtgt cgcacgacga actccggttc cagctcgacg
    18181 ggttggccgg accataccgt gaactgcccg accgccgggt gcacgagctg ttcgagcagc
    18241 gggtcgtggc gcacccggac gccgtcgcgg ccgtgcacgg cgaccgccgc tggacctacc
    18301 gggagctcaa ctcccgtgcc aaccagctca gtcgggccct gctggtccgg ggcctcggcc
    18361 gtgagggcgt cgtcgcggtg gtgaccgagc ggaacctgga ctggatggcg gccgtcctcg
    18421 cggtgttcaa ggccggcggg gcctatctgc ccgtcgagcc gcacttcccc gccgagcgca
    18481 tcgcctccac cctcgcccgg gccggctgcg agctggtcct caccgaggag ggcagcacgg
    18541 ccaccctgga cgaggccctg cccgcgctgc ccggggtgca gcggctgctc gtcggggagg
    18601 cgtacgacga ggcccatccg gactccgacc tcggcatgga gatcgcgccg gaccggctgg
    18661 cgtacatcta cttcacgtcc ggttccacgg gcgagcccaa gggcgcgatg tgcgagcacg
    18721 ccggcatgct caaccatctt caggccaagc tggacgacct cgacatcggc gagggggacg
    18781 tggtcgcgca gaccgcgccc cagtgcttcg acatctccct gtggcagctg ctggccgcgc
    18841 cgctggtcgg cggtcggacg ctgctcgtgg agcaggaggc gatcctggac gtcgaacagt
    18901 tcgtcgaccg gatcgccgac ggccgggtga acgtgctcca ggtcgtgccg tcgtacctcg
    18961 aagcggtcct cgcccatctg gagcagacgc cccgggaact gcccgatctg cgccgggtct
    19021 ccgtcaccgg ggaggcgctg aagaaggagc tggcggagcg ctggttcgcc accgagccgg
    19081 ggattcccct ggtcaacgcc tacgggctga cggagacctc ggacgacacc aaccacgagg
    19141 tgatggaccg ggctccggag gggggccggg tgccgctggg ccgtccggtc cgcaacgtcc
    19201 gtgtgtacgt cgtcgacgaa cacctctccc tcgtcccgct gggcgctccg ggggagatcg
    19261 tcttctccgg ggtctgtgtc gggcgggggt acgtcaacga tcccgagcgc acccggcggg
    19321 ccttcaccac cgacccgtac ctgccgggtg agcggctgta ccgcagcggt gaccacgggc
    19381 gctggcggcc cgacggcaag ctggagttcc tgggccgccg ggacacccag gtcaaggtgc
    19441 gcggcttccg catcgagatc ggcgaggtgg agaacgcgct actgcgggtg gcgggtgtgc
    19501 gggacggggc ggtggtggtc gccaagggcg cgcatctggt cgccttccac tccgggcgtc
    19561 cgctcgcggg cgaggagctg cgggaccggc tggcggcctc gctgccggcg tacatggtgc
    19621 cgtcggtgtt ccactggcgc gagagcctgc cgctgaccgc caacggcaag atcgaccggc
    19681 ggacgctcac cacgctggcc gaacaactcc ccgccgtgcc aggcgagtcg ggcgggcttc
    19741 cggccacgcc gacggaggag cggctggcta ccgcgtgggc cgaggtgctc ggtgtggcgc
    19801 ggtccctgat cggccgtcgc gaccacttct tcgaccgggg cggcacctcg ctgtcggcgg
    19861 tgaagctcgc gatcgccctg gaccgggcgg tgtcccccaa ggacgtgacc gcgtatccgg
    19921 tgctgtccga cctggccggg ctgatcgaca cgagggccgg cgcgaacacc gtagggaggc
    19981 cgacgtcatg agtttcctga gccgccgagg cgccgcgagc cgccgtcgca agaacacggg
    20041 gatggcggcg ccctcctcaa ctgccctgcc gctaccggac atcgagtcgg cggccggcag
    20101 gccgccgctg ctcatggtct cccccgccga tcccgctgcc cactgggtcg ccgggcgacg
    20161 ggaggccctg cgtgccgccg tcgccgagca cggctcggtg ctcgtgcgcg gtctcgggct
    20221 gcgggacgcc accgaagtcg gagccgtctt ccgggcgttg gcggacacgc tgatgagcga
    20281 gaaggaggcc ttcgcgccgc ggcggacgta cgcggacggc gtgtactcct cgacggcctg
    20341 gccgccgaac caaccgatgt gcatgcacca cgagttgagc tacacggtgg agttccccgg
    20401 cctgatgctc ttcgcctgcc tcgaagccgc cgagcggggc ggggcgaccg gggtcgccga
    20461 cgcggaggcc gtactcgccg cgctgccacc cgagttgacc gagcggttcg agcgggacgg
    20521 ctggctgctc acccgctcgt acaacgacga gatcggcgcg tcggtcgccg aggcgttcgg
    20581 caccgacgaa cggaccgtcg tcgaggccta ctgccgggcg cacgccatcg agttcgcctg
    20641 gcagcccgac ggctccctgc acacccggca gcggcgcgcc gccgtgctcc gccatccgat
    20701 gaccggccgg cgctgctggt tcaaccagat cgcgttcctc aacgaatgga ccatggacgc
    20761 cgaggtgcgc gagtacctgg tggacatgta cggagccgac ggtctgccct tcaacacccg
    20821 ttacggcgat ggcgatccga tcggcgagga cgccgtccgg accctcaacg agatctacga
    20881 ggcgcacacc gtccgcgaac cgtggcggcc cggcgacctc ctgctcgtcg acaacatccg
    20941 ctccgcccac agccgtgagc ccttcgaagg gccgcgcgag gtgctggtgg gcctggcgga
    21001 tccggtacgg ccgaccgact gcgccacgcg ggactccgac acacaggact cccgctcgca
    21061 ggactcccgc tcgcaggacc ccgactcgaa ggactccgac gcgaaggacg aggtgagctt
    21121 ccgatgaccg aggttccggg tttcgccgtg atctccggcg cccaggtaca gcaggccctg
    21181 cggggccggg agggggagat cgtcgacctg gtcgaatccg cctacctgtt gcacggagcg
    21241 ggggacacgg gcgacacggt caatccgccg tcgtacttcc tccgcttccc cgaccgtccg
    21301 tcctcgcgga tcatcgcgct gcccgcctcg ctgggcggga agttccaggt ggacgggttg
    21361 aagtggatct ccagtttccc ggagaacacg gcgtccgggc tgccgcgcgc gtccgccgtg
    21421 ctgatcctca acgaccacac caccggctat ccgttcgcgt gcctggaggc ctcggtcatc
    21481 agcgccaccc ggacggccgc gtcggcggca ctggcggccg accggctgag cgagcgccgg
    21541 ggggcgccgc gcccggccag ggtcggattc ctcggcacgg gcctgatcgc ccggtacatc
    21601 cacaccttcc tcgaggcgac gggcttcgcg ttcgaggagg tgggggtgca cgatctgtcc
    21661 gccgacagcg cggccgggtt ccgggggtac ctggaacggt cccacgcgag cgggcgcgtg
    21721 accgtgcacg agagtgccga ggacgtgatc cgggcgagcg acctggtggt cttcgcgacg
    21781 atcgcgggcg agccgcacat ccacgaaccg aagtggttcg cccaccaccc gctggtgctg
    21841 cacgtgtcgc tgcgcgatct cgcgcccgag gtgctgctcg cgtcggcgaa cttcgtcgac
    21901 gacgtcgagc actgtctcaa ggcgaacacg tcaccgcacc tgaccgaaca gctcaccggc
    21961 gcacgggact tcctcgatgg aacgctccat gacgtcctca ccggccgggc gaccgtgccg
    22021 acggaccgtc cggtgatctt ctcgcccttc ggcctcgggg tcctcgacct cgcggtcggc
    22081 ggttatgtcc acgacgaagt ggcccgctcc ggcggactac gggtcgtgga cgacttcttc
    22141 cacgagctgc gccgccacgg ctgacctgcc gggcgcagcg agtaccacag tgcacaacca
    22201 ggggggccgc agtgccagtc atatccgttc ccacggactt caacgaagag gagctgtacg
    22261 tcgatctgcg ccaggtcgtc ggacacgagc tcttcctgaa atgcgaggga ttcaacttcg
    22321 ccggctcgat caagctcaag gccgcgaccg agatggtgcg ggccgccgaa cgggacggat
    22381 gtctccggcc gggctcgacg ctcgtcgagt cgtcgtccgg caatctcggc gtcgcgctga
    22441 gcatgatcgc ggcgagccgg ggttatcggt ttctgtgcgt gaccgattcc cggtgcaatc
    22501 cgcagacccg gcgcctgatc gaggcgctgg gcagccgggt gcacgtcatc tccgagccgg
    22561 atccgcacgg cggtttcctc ggcgcgcgga tcgcgtacgt ccgcgcgctg tgcgccgccg
    22621 acccggagta cgtgtggctc gaccagtaca ccaatcaggc gaactggcgg gcgcactacc
    22681 gcaccaccgc gcccgccatc gcccggcagt tcccgcggct ggacgtgctg ttcgtggggg
    22741 tcggcacctc cgggacgctg atgggctgcg cccagtggtt ctgggaacga cggcgccggg
    22801 tgcggatcgt cgccgtggac agcgtggggt cggtcgcctt cggcggggcg ccgggccgcc
    22861 ggatgatccc ggggctcggc acgagcgtgc ccccggcgct gctcgacccg tcctgtgtgg
    22921 acgacgtcgt ccgggtggag gagatcgaca ccgtacgggc ctgtcaccgc atggcccggc
    22981 gcggcttcct cttcggcggc tccaccggca cggtcgtcag cggcgccacc gactggctga
    23041 accgcaacgg ctcccccgac atcacggcgg tggcgatctc cccggacctc ggcgagcgct
    23101 acctcgacac catctaccgg ccggggtggc cgctggagca gtacggggag ggcgtactgg
    23161 acccggagga cgagttcggc acaggtgaac tggggacggg cgagctggcg gcgcccgtct
    23221 gagccgagac cagccgtccg gcgccggaca gaacgggtcc ggcgccgggc acctgcccgg
    23281 gcctgcccac cggacaccgg tgggcgtcgc ggtgccgatg cgctgccgag gggtaggttc
    23341 cagatatggc tgcccgcacc cacgaagtga ccaatcaggc tccgcccctg gtggactacg
    23401 acgtcttcag cgccgaccgg gccctggcgg aggcggtcga ccggcatctg gccccggacc
    23461 tcctcgacga ggcgcggggc gagctgtcgg ggctcggccg tacggcgggc tccgtgcagg
    23521 tgcaggagtg gggacggctg gcgaacgaga atccgccgaa gctgcgcacg cacgaccggt
    23581 acggcaaccg gatcgacgag gtggagttcc acccgtcctg gcaccggctg ctcggcaagg
    23641 gcgtctcggc ggggctgacg gcggcctgga cccgtccggg cgggcatgta cggcgcgcgg
    23701 ccgggttcgt cgtctggtcc caggtcgagg ccggcaacgg ctgcccgctg tccatgaccc
    23761 acgcggcggt acccgccctg cgcacggacc cggcactcgc cgccgagtgg gagccgcggc
    23821 tgacgtcccc gctctacgac tgggatctgc ggcccgccga ccagaaggcc ggggccctct
    23881 tcggcatggg catgaccgag aagcagggcg gcagcgacgt acgcgccaac acgaccgggg
    23941 cgcgccccct ggccgaggag gggacgtacg agctgacggg ccacaagtgg ttctgctcgg
    24001 cgccgatgtc ggacggtttc ctggtactgg cacaagcgcc gggcggcttg acgtgtttcc
    24061 tcgtgcctcg ggtactggcg gacggctcgc ggaacgtgtt ccgcatccag cggctcaagg
    24121 acaagctggg caaccggtcg aacgcctccg ccgaggtcga gttcgacggg acgtgggcgc
    24181 gccgggtcgg ggacgagggc cgcggggtgc gcacgatcat cgagatggtg tcggccaccc
    24241 ggctggactg cgcgctgggc gcggcctccc tgatgcggca ggcggtggcc caggcggtgc
    24301 accactgcgc gtaccgggag gcgttcggcg gccggctgat cgacaagccg ctgatgcgca
    24361 atgtcctcgc cgatctcgcg ttggagtcgg aggcggcgac gacgctggcg atgcggctgg
    24421 ccgcggcgta cgacgcggcc gaggcgggca acgagaccga acgctcgttc ctgcggctcg
    24481 cggtgccggc cgccaagtac tgggtgacca agcgctgcac cccgaccgtg gtcgaggcct
    24541 ccgagtgcct cggtggcaac ggctatgtcg aggagtccgg catgccccga ctgctgcgcg
    24601 agtccccgct caactccatc tgggagggcg ccggaaacgt gcaggccctg gacgtgctgc
    24661 gggcactcca gcgggaaccg ggggccctcg acgcctacct gcgggaagtg ggccgggccc
    24721 ggggagcgga ccaccggctc gacggcgcca tcaagaacct gctgaccgaa ctcgccgatc
    24781 tcgacggcat cgaggcccgc gcacgccggc tcgtggagcg cctcgccctc gtcctccagg
    24841 gcgcgctcct cgtgcggtac gcgcccccgg cggtcgccga cgcgttctgc gcctcccggc
    24901 tgggcggcga ctggggcacg gccttcggca cgctgccgca cacgctggat ctggcgtcgg
    24961 tggtggaacg ggcgcgtccg gtgagctgag ccgccgccgg gcaggagacg ccccctttcg
    25021 cggggggcct ttttcgagtg gtacgacgcg ggggtggtgc tgcgccgaca cggcaccacc
    25081 cccgcttttc tggccccttc gagcggagca catacgccgc accgggcgac gtcgaacaag
    25141 tctcaagcag ccagggccgg ttcgccagag ttgcaggggg ttgcaacgtg tccgcgctct
    25201 gtggccggag tgtgtccctc cgtggccgag gagcggcaga ctatgaagcc cgcagtcaac
    25261 gccgtcacgc agatccggac ttccacggcc accaggggcc gtggcgcgat cgggcctgcc
    25321 ggggaggaac gagtgccgca ctcgccgatg gaagtcgcgc ggctcaccgc cacggacgcc
    25381 gcccgggcgg cacgggtcct cggcgaggta cgtgcctccg ccctcgacgg ccgacggccg
    25441 aaaaccgccc cccgcccggc gatccgggag tcctggagcc gcatggtcca cagcggcgtc
    25501 gaccccgacc acgacttccg gtccgacctg ctcagccagg acgagatcga gcgccgccgt
    25561 cagagcaccc gcctgcggca cgtcctgccg gtcctgcgcg aggggctgct ctccctcgcg
    25621 gacaccgcgc agcacataat gatggtcgcg gacgccgacg cccgggtgct gtggcgcgag
    25681 ggcagtacgg ccgtgctccg caaggcggac gggcagggtc tcgggatcgg cgcggactgg
    25741 cgcgaggaga ccatcggcac caacggcgtc ggcacccccc tcgtctcccg ccgccccgtg
    25801 caggtcttct ccgccgagca cttcgtccgc gccctgcacc cctggacctg caccggcgcc
    25861 cccatcaccg acccgcgcga cggccgtctc ctcggcgcgg tcgacatcag tggccccctg
    25921 gagaccctgc atccctccac cctcgccctg gtcgacgccg tcgccaagct cgcccaggcc
    25981 cggctacgag aactgcacct gacctcgctc gaagaactgc gggcggtggc ggcgccggtg
    26041 ctggcccgta tcggcggccc cgcgatcgcc gtcgaccggg acggctggac ggccgcggtg
    26101 accggcatgc cgtacaccag ccgcgtcgcc ctgcccaagt ccctctcccc cggccgctgc
    26161 cggctctccg cgctcgggct gtgcaccgtc gagccgctgc ccgccggctg gctgatacgc
    26221 cccacggcgg accccgcgcc cgcctccacg accacgcaca tcaccctcga cgtctcccac
    26281 ccccgccgct ggaccgtcac cgtcacaggc tgcgccggtt cctggaccca tgaactcacc
    26341 ccccgccacg ccgaactcct ctacctcctc gccctccacc gcggcggccg cagcgcctca
    26401 gccctcgccg acgacatgtt cggcgacccc gcccgcacgg tcaccgtccg cgccgagatg
    26461 tcccgcgtac gccgctacct cggcgccttc ctcgaccacc ggccgtaccg tttcaccgaa
    26521 cgggccgacg tcgaagtcct cctccccgag gccccgttgg acctgctgcc gcattcggtg
    26581 gcgccggggg tggtgcgggc gcggggagcg gcaccggcgg gccggccgca cccccttccc
    26641 ggtgaacgga tcatgtcccc agggtgaggg atctccctgt atttcacgcg tcctcggcgt
    26701 gacacgtgtc ccactgccgt agcatcgctg ccaggccgcc ccacctgcct ctgcgtcaag
    26761 gtcttgttct cggtaggcag ttggccgtcc ccgggaggtt ttgtgaagca ccgcggtagg
    26821 caccgtcgac gcagaagggg acgtgcgctg cgtgcgtccc tggcggggac cgcgctggcg
    26881 ctcacggcgg cggccacgct gatcagcacg tcgcaggcgg cgggcgggga gacgccgggc
    26941 gcgctgtcct cgatcggctc ggccggtgag ctgcgcgggc ttcagctgcg ggagaccctg
    27001 accgacgaga ccgggctgtc catcctcgcc gacgagatgg gcggtggggt cggtgtcgac
    27061 gaggtgctgg agagcgccaa ccatgtgatg cgcgacgagg acgactgctt cgactccgag
    27121 aaggacaatc tgcccgtcga accggcggcc tcacgggcgt actgctggga gccgggcgac
    27181 gcggtcaacg acaagtgggt cccccggtcg gtcaccacgt cccggaacaa ccaggtcatc
    27241 gtgtccgggt ggaccagcga gacgggtgac ggcgacacga gcgccgacgg tgcgggtgcc
    27301 gaccgtacga acggcgacag caccgacggc gaagggctca ccagggtcgc cttcatcgac
    27361 gccaagaacc ccgcgagcct caagtaccgg tgggttctgc tggtcgtgcc gaaggccgac
    27421 ggacagggct tcgaggggct gcggtcccgg ctcggcggca tggcctggta cgaggacaag
    27481 ttgatcgtca ccgcgcgggg cccggagagc ggcggacggc aggacgactc cctgtacgtg
    27541 ttcgacatgg ctcgcttcct ccgcgccgat gtgaccgaca gcgatgtgat cggcaaggtc
    27601 ggcgacggct ggtcggccca tcactaccgg tacgcgctgc cggcggtcgc cacctacagc
    27661 ccggcggcgg gcggcggctg tgacgcgcgc gacaacgacg gggtgccctg cttcggttcg
    27721 ctctccctcg accggacgtc ggcgcggccc agcctcgtcg cgagcgagtc gttccagccg
    27781 ggccgtgagg agcccacccg cgtctggcgc tacgccctcg acaccaccgc cgaccgcacc
    27841 ggcctgctca ccaccaccgg gcgctggagc gacgccgtcg ccaccgaggc gtacgagacc
    27901 gaggccaccg gtgtccgggg ggtcctctcc cacggcgggg actggtacat cgggcaggcc
    27961 ggcgaggggc gtgacgagca cgacaccctc tggcggcagg accaggacgg cgcgaaggcc
    28021 gccaagtgcg cggcggacaa gtcggacgag aagtcgggcc tgcggacgtc cgcctgctgg
    28081 gggcggcaca ccgcctccct ctcctactcg ccggagaccg acgaggtgtg gacgctcacc
    28141 gacccgatcc ccgagcgggt gctgtacgcg gtgaagctgt cggacgtcga cggcacgctg
    28201 ggctagaaag cccgccccga caccgagcca gggcacccga cccgacaccg agtcagggag
    28261 cccggccccg gacgctggtc agggcgcccg gcccggacgc ccggtcagcg agtccggccc
    28321 ggccgggcaa ccggcccgcc cttggaggcg ggccgggccc catgattccc tggccccatg
    28381 agcagcaacc ccgtcaccac ctggtccctg gagcagactt cgccgagcga cctgcttccc
    28441 gccgccgccc ccgacggcga cgacatccgt atcgtccgct ccgaggtccc ctcccccgag
    28501 ttcagccgct tcctgtacgc ctccgtcggc ggcgacatcc actggatcga ccggctttcg
    28561 tggtcgtacg accgctggca ggagcacctg ggacggccgg gcgtggagac ctgggtcgca
    28621 tacgatcggg gcacgcccgc cggttatgtg gagctggagc cacaggacga cggggtcgtg
    28681 gagatcacgt atttcgggct gatcccggcc ttccggggcc ggcgcatcgg cggacacctc
    28741 ctgtcctgcg ggacggcccg cgcctgggac ctcgccgagc ggtggccggg gctgccgccg
    28801 accaagcggg tctggctgca cacctgcagc ctggacgggg agcacgccat ggggaactac
    28861 ctgcggcggg ggttcaccct gttcgacacg gaggtgacgg aggaggcgga tgttccggcg
    28921 ccgggaccct ggcccggggc gaccgcgccc acaccatgac ccacatcaca ttgtctcgac
    28981 atgcgagaca tcctcgtccg acatatggac tatggtggac tcggtctaaa gagccgtgac
    29041 acgcttccgt catgtctgga actggaattg ccttggtgag tcggcggcac gtcgacctcg
    29101 gccgcatgtc cagcgccatc tgtccggtga gctgacgccc caccgcgagg ggtccgacga
    29161 ccccgggcga cagcgccgca cccccctctg tttcagccgg cgcaagggcg cgcaggcgcc
    29221 gcacacgtcg cattcacgtg tgcccgcatg cgcgcgcaag cgcggtcaga gccgcttcca
    29281 cgcctttccc gaaggacata cacaccatgg ccgccacccc gcagaacccc gccacgcccc
    29341 gccgcaaggt gagccgtcac cgtggcgagg gccagtgggc cgcgggacac ttcaccccgc
    29401 tgaacggcaa cgagcagttc aagaaggacg acgacggtct caatgtgcgg acacgcattg
    29461 agacgatcta ctcgaagcgc ggcttcgact cgatcgaccc caacgacctg cgcggccgga
    29521 tgcgctggtg ggggctgtac acccagcgca agcccgggat cgacggcggc aagaccgcga
    29581 tcctggagcc ggaggagctg gacgacaagt acttcatgct gcgggtgcgg atcgacggcg
    29641 gtcgcctcac cacccagcag ctccgggtga tcggtgagat ctcgcaggag ttcgcgcggg
    29701 gcacggccga catcaccgac cggcagaacg tccagtacca ctggatccgg gtcgaagatg
    29761 ttcctgagat ctgggaccgc cttgaggccg tcgggctgtc caccaccgag gcctgcggtg
    29821 acacgccccg tgtgatcatc ggctcacccg tcgccgggat cgccgcggac gagatcatcg
    29881 acggcacgcc cgcgatggac gagatccacc ggcggatcat cggcaacccg gacttctcga
    29941 acctgccccg caagttcaag tccgcgatct ccggctcccc gctgctcgac gtggcgcacg
    30001 agatcaacga catcgccttc gtcggtgtcc gccaccccga gcacggcccc ggcttcgacc
    30061 tctgggtcgg cggcggcctg tccaccaacc ccaagatcgg gcagcggctc ggcgcctggg
    30121 tgccgctgga cgaggtcgcg gacgtgtacg agggcgtcat ctcgatcttc cgcgactacg
    30181 gctaccggcg gctgcgcacc cgcgcccgcc tgaagttcct gctcgccgac tggggcacgg
    30241 agaagttccg ccaggtcctg gaggacgagt acctcaagcg gaagctgatc gacggcccgg
    30301 cgcccgacca gccggtggcg cgctggcgcg accacgtggg agtgcacccg cagaacgacg
    30361 gccggtacta cgtcgggttc gccccgcgcg tcggccgggt ggacggcacc acgctgacga
    30421 agatcgccga cctcgccgag gcacacggct cgggccgtgt ccggaccacc gtcgagcaga
    30481 agatgatcgt gctcgacgtc acccaggagc aggtcgactc gctcgtcgcg ggcctggagg
    30541 cgctggacct cacggtgcac ccgtccccgt tccggcgcgg caccatggcc tgcaccggca
    30601 tcgagtactg caagctcgcc atcgtcgaga cgaaggcgcg cggctccgcc ctgatcgacg
    30661 aactggagcg ccgtatcccg gagttcgacg agccgatcac catcaacatc aacggctgcc
    30721 cgaacgcctg tgcgcgtatc caggtggcgg acatcggtct caagggacag ctcgtcctga
    30781 acgacgcggg cgagcaggtc gagggcttcc aggtgcacct gggcggcgcg ctcggcctgg
    30841 aggccggctt cggccgcaag gtacgcggtc tgaaggtcac ctccgacgaa ctgcccgact
    30901 acgtcgagcg ggtgctcaag cggttccagg aggagcgcga ggacggcgag cggttcgcca
    30961 cctgggtcac ccgcgccagc gaggaggccc tgtcgtgagc gagcgagccg cccccttcta
    31021 ctgcccctac tgcggtgacg aggacctgcg cccgaacgaa gaaggtcacg gcgcgtggga
    31081 atgcggggcc tgcaatcgag ccttccagtt gaagttcctc gggctgctgg cccggggcgt
    31141 gagccgaggg agcgcgacgg tgtcgagaga ccgagcgcgc ggaggccccg acgaaggagg
    31201 ggctgagcac ggtcggtccc tcggcgccgg caatggcgct ccctcggctc acgcccctca
    31261 aaaaagcagc cttcagcgag ccgacagcgg aggggatcac atatgactac cgttcaggcg
    31321 gattccgata cagccgcgtc cttcgaggac gccgccgacc ccgaagcggc gaagcgcgcc
    31381 gagctcaagg cgctcgccga gcaggccggc cgcgacctgg aggacgcctc ggcactggag
    31441 atcctccagt gggccgtgga caccttcggc aagcgcttct gcgtgacctc ctccatggag
    31501 gacgccgtgg tcgcgcacct cgcttcccgc gccaggcccg acgaaggccc ggtcgacgtg
    31561 gtcttcctcg acaccggcta ccacttcccc gagaccatcg gcacccggga cgcggtcgag
    31621 gccgtgatgg acgtcaacgt cctcacgatc accccgcgtc agacggtcgc cgagcaggac
    31681 gccgagtacg ggcccaagct gcacgaccgt gaccccgacc tgtgctgctt cctgcgcaag
    31741 gtcaagccgc tcgaagaggg tctggcccgg ttcgacgcgt gggcgacggg cctgcgccgc
    31801 gacgagtccg agacccgggc gaacaccccg gtcgtcggct gggacgacaa gcgcggcaag
    31861 gtcaagatct ccccgatagc gcgctggacg caggacgacg tggacgccta cgtcgccgag
    31921 cacggcgtgc tcaccaaccc cctgctcatg gacggctacc cgtccgtggg ctgcgccccc
    31981 tgcacccgcc gcgtcgcccc gggcgaggac gcgcgggccg gccgctgggc cggcaacgcc
    32041 aagaccgagt gcgggctgca cctgtgaccg ccgcagcgcc tgccgagacc gccgacaccc
    32101 ccgagaacac cgtccccgtg acggaccgcg ttcctgtgac gaaccaggag aaccaagtga
    32161 cgaccggagc caccggagcc accgtctggc tcacgggtct gccgagcgcc ggcaagacca
    32221 ccatcgccta cgagctcgcg ggccgactgc gcgaggaggg ccacctcgtg gaggtcctcg
    32281 acggcgacga gatccgtgag ttcctcaccg cggacctcgg cttcagccgc gccgaccggc
    32341 acaccaacgt gcagcgcatc ggcttcctcg ccgacatgct cgcccgtaac ggcgtcaagg
    32401 ccctggtgcc ggtcatcgcg ccgtacgccg acagccgcga ggcggtgcgc aagcgccacg
    32461 acgcgagcgg cgccgcgtac gtcgaggtgc atgtggccac gccggtcgag gtgtgctccg
    32521 tacgcgatgt gaagggcctg tacgccaagc aggcggccgg tgagatctcc gggctgaccg
    32581 gggtcgacga cccgtacgag gctcccgaga cccccgacct gcgcatcgag tcgcaggacc
    32641 agacggtcca ggagtccgcg gcgcttgtgc acaagctgct caccgagagg ggtctggcat
    32701 gacgacgacc gtcgcggccg tctccgagga gaccggcacc ccgtacaccc tctcgcacct
    32761 ggactcgctg gagtccgagg ccgtccacat cttccgcgag gtcgcgggcg agttcgagcg
    32821 gccggtgatc ctcttctccg gcggcaagga ctccatcgtc atgctgcacc tggcgctgaa
    32881 ggccttcgcc ccggcggcga tccccttcac gctgctgcac gtcgacaccg ggcacaactt
    32941 cccggaggta ctggagtacc gcgaccgcac ggtggcccgg cacggcctgc gactgcatgt
    33001 cgcctccgtg caggactaca tcgaccgggg tgtgctgcgg gaacgccccg acgggacccg
    33061 gaaccccctc cagaccgtgc cgctcaccga gaggatccag gcggagaagt tcgacgccgt
    33121 cttcggtggc gggcgacgcg acgaggagaa ggcgcgcgcc aaggagcggg tgttctccct
    33181 gcgggacgag ttctcgcagt gggacccgcg ccgccagcgg cccgagctgt ggaacctgta
    33241 caacggccgc cacgcgcccg gcgagcacgt ccgtgtgttc ccgctctcca actggaccga
    33301 gctggacgtc tggcagtaca tcgcccgcga gggcatcgaa ctgccggaga tctacttcgc
    33361 ccacgagcgt gaggtgttca tgcgggccgg catgtggctg accgccggcg agtggggcgg
    33421 gcccaaggac ggtgagaccg tcgagaagcg gcaggtgcgg taccggacgg tcggtgacat
    33481 gtcctgtacg ggtgccgtcg actccgacgc gaccacgctg gacgccgtga tcaccgagat
    33541 cgccgcctcc cggctcaccg agcggggcgc gacgcgcgcc gacgacaaga tgtccgaggc
    33601 cgcgatggaa gaccgtaagc gcgaggggta cttctaagca tgagcacgac cacggaactc
    33661 accgagacga ccctgctgcg gttcgccacc gccggttcgg tcgacgacgg caagtccacc
    33721 ctcgtcgggc ggctgctgca cgactccaag tcggtcctca ccgaccagct ggaggccgtg
    33781 gagcgcgcct cggcgagccg tggccaggag ggccccgacc tcgcgctgct caccgacggt
    33841 ctgcgggccg aacgggagca gggcatcacc atcgacgtgg cgtaccgcta cttcgccacg
    33901 gccaagcgcc ggttcatcct cgccgacacc cccggccatg tgcagtacac ccgcaacatg
    33961 gtgacgggtg cctccaccgc cgagctgacg gtgatcctcg tcgacgcccg caacggggtc
    34021 gtcgagcaga cccgccggca cgccgcgatc gccgcgctgc tgcgcgtccc gcacgtggtc
    34081 ctcgccgtca acaagatgga cctcgtcggg tacgaggaga cggtcttcgc ggcgatcgcc
    34141 gaggagttca cggcgtacgc ctccgagctg ggcgtcccgg agatcacctc catcccgatc
    34201 tcggcgctcg ccggtgacaa cgtggtggag ccgtccgcca acatggactg gtacggcgga
    34261 ccgaccttcc tggagcacct ggagtccgtg ccggtcgccc acgacctggc gcactgccac
    34321 gcccgtctcc ccgtgcagtt cgtgatccgt ccgcagaccg ccgagcaccc ggactaccgg
    34381 gggtacgcgg gccagatcgc ggccggtacg ttccgcgtcg gcgactccgt gacggtgctg
    34441 ccgtccggcc gcacgacgaa ggtgacgggc atcgacctgc tcggcaagcc ggtcgctgcg
    34501 gcctggaccc cgcagtcggt gaccctcctc ctcgaggacg acatcgacat ctcacgcggc
    34561 gatctgctcg tgcccaccaa ggacgcgccc gcgaccacac aggacatcga ggcgacggtc
    34621 tgccatgtgg ccgaccagcc gctgaccgtg ggccaccgcg tgctgctcaa gcacggcacc
    34681 cgcacggtca aggcgatcgt caaggacatc ccctcccgcc tcacgctcga cgacctgtcc
    34741 ctgcacccgc acccgggaca gctcgtcgcg aacgacatcg gccgggtcaa gatccgcacc
    34801 gccgaggcgc tgccggtcga ctcgtacgcc gactcccgcc gcaccggttc cttcatcctg
    34861 atcgacccgg cggacggcac cacgctgacc gccggcatgg tcggcgagtc gttcgcctcc
    34921 ccggagcccg tcaaggacga gtccgaggac gacgggtggg acttctgaca tgaacctcca
    34981 ggacttctac g
//
