LOCUS       NZ_CP102512            26689 bp    DNA     linear   CON 11-FEB-2024
DEFINITION  Streptomyces sp. CA-210063 chromosome, complete genome.
ACCESSION   NZ_CP102512
VERSION     NZ_CP102512.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CA-210063
  ORGANISM  Streptomyces sp. CA-210063
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10859970)
  AUTHORS   Nielsen,J.B., Gren,T., Mohite,O.S., Jorgensen,T.S., Klitgaard,A.K.,
            Mourched,A.S., Blin,K., Oves-Costales,D., Genilloud,O., Larsen,T.O.,
            Tanner,D., Weber,T., Gotfredsen,C.H. and Charusanti,P.
  TITLE     Identification of the Biosynthetic Gene Cluster for Pyracrimycin A,
            an Antibiotic Produced by Streptomyces sp
  JOURNAL   ACS Chem Biol 17 (9), 2411-2417 (2022)
   PUBMED   36040247
REFERENCE   2  (bases 1 to 10859970)
  AUTHORS   Joergensen,T.S., Gren,T., Blin,K. and Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2022) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 05-AUG-2022
            Assembly Method :: Flye v. 2.9-b1768; Polypolish v. 0.5.0; POLCA
            polisher from MaSuRCA v. 4.0.5
            Assembly Name                     :: M642_aaa1.6.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 55.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 11:12:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,501
            CDSs (total)                      :: 9,410
            Genes (coding)                    :: 9,051
            CDSs (with protein)               :: 9,051
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 359
            CDSs (without protein)            :: 359
            Pseudo Genes (ambiguous residues) :: 0 of 359
            Pseudo Genes (frameshifted)       :: 141 of 359
            Pseudo Genes (incomplete)         :: 302 of 359
            Pseudo Genes (internal stop)      :: 23 of 359
            Pseudo Genes (multiple problems)  :: 101 of 359
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:19:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1048542
            Orig. end                         :: 1075231
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102512.1.
            Bacteria and source DNA available from Tilmann Weber, Dr.
            Professor, Novo Nordisk Foundation Center for Biosustainability,
            Kemitorvet, 220, 327D 2800 Kgs. Lyngby, Denmark.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26689
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26689
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26689
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16689](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16689)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    754..770
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.74"
                     /tool="antismash"
     misc_feature    1776..1789
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.93"
                     /tool="antismash"
     gene            2116..2913
                     /locus_tag="JIX56_RS04590"
                     /old_locus_tag="JIX56_04590"
     CDS             2116..2913
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="JIX56_RS04590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04590"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_257537471.1"
                     /transl_table=11
                     /translation="MTQQVPSTEPELTGVRNFRDVGGLPTVDGRRVRHGVLFRSGHLAH
                     ATDEDTAFLASLGLHTVFDFRNAADQKLEGPDVELPGVLNVNLPLSDPADGAEFWKMVR
                     DGDLDQLRALLDDGKAAGRMIASYRTIIKDRTAEHSRVLHALAEDSVPALMHCAAGKDR
                     AGLSIAITLLTLGVEREAIVADYLESNAKHRRYKVHRSSTSASAYSPEVMELLSPLFDA
                     RAEYLQTAFDTVEETWGDVDTYLEQGLKMTPQTRERLRERLLD"
     gene            complement(2940..3062)
                     /locus_tag="JIX56_RS04595"
                     /old_locus_tag="JIX56_04595"
     CDS             complement(2940..3062)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329167.1"
                     /locus_tag="JIX56_RS04595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04595"
                     /product="DUF6126 family protein"
                     /protein_id="WP_257537472.1"
                     /transl_table=11
                     /translation="MTDLEEKFPRALWVRLIIYIAVGHLFAAFVYLLFEVGAKQ"
     gene            complement(3059..3691)
                     /locus_tag="JIX56_RS04600"
                     /old_locus_tag="JIX56_04600"
     CDS             complement(3059..3691)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999178.1"
                     /locus_tag="JIX56_RS04600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04600"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_257537473.1"
                     /transl_table=11
                     /translation="MSPSEGTHPPEPPMDGELPVVAPQLRALRRRASLTLEAAARAAGL
                     SPAHLSRLETGQRQPSLPMLLALARIYGTTVSALLGESVPERDAVLRASDREPTKAGGW
                     TYWQAGAPGRGMQALRVHVPYGSQGDIVRVHPGEEWLYVLKGRLRLRLGDTTHLLAPGD
                     SAHFDSLTPHRIAAADRDGADLLFVHTLLQSPTAALCLGPTTPGETP"
     gene            complement(3784..5193)
                     /locus_tag="JIX56_RS04605"
                     /old_locus_tag="JIX56_04605"
     CDS             complement(3784..5193)
                     /NRPS_PKS="Domain: Aminotran_3 (49-371). E-value: 2e-88.
                     Score: 288.6. Matches aSDomain:
                     nrpspksdomains_JIX56_RS04605_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329186.1"
                     /locus_tag="JIX56_RS04605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04605"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_257537474.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.5e-86, bitscore:
                     289.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVEPAAGTEEFDLGRLLAERGAERYELHARHLNHQLPRMLHTI
                     GFDKVYERAEGAYFWDANGDDYLDMLAGFGVMGLGRHHPVVRKALHDVLDARLADLTRF
                     DCQPLPGLLAEKLLTHSPHLDRVFFGNSGTEAVETALKFARYATGRPRVLYCDHAFHGL
                     TTGSLSVNGEAGFRDGFAPLLPDTAVPLGDLDALARELEKGDVAALVVEPIQGKGVHEA
                     PPGYLRAAQELLHRHKALLIVDEVQTGLGRTGDFYAYQHEDGVEPDLVCVAKALSGGYV
                     PVGATLGKEWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMENEQIVAGARATG
                     ELLKSRLAALVDKYELLSEVRGRGLMIGIEFGRPRSLKLRSRWTMLQAARKGLFAQMVV
                     VPLLQRHRILTQVSGDHLEVIKLIPPLVIGEREVDRFVEAFTEVMDDAHSGGGLMWDFG
                     KTLVKQAVANR"
     aSDomain        complement(4081..5046)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JIX56_RS04605_Aminotran_3.1"
                     /evalue="2.00E-88"
                     /label="JIX56_RS04605_Aminotran_3.1"
                     /locus_tag="JIX56_RS04605"
                     /protein_end="371"
                     /protein_start="49"
                     /score="288.6"
                     /tool="antismash"
                     /translation="VYERAEGAYFWDANGDDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DARLADLTRFDCQPLPGLLAEKLLTHSPHLDRVFFGNSGTEAVETALKFARYATGRPRV
                     LYCDHAFHGLTTGSLSVNGEAGFRDGFAPLLPDTAVPLGDLDALARELEKGDVAALVVE
                     PIQGKGVHEAPPGYLRAAQELLHRHKALLIVDEVQTGLGRTGDFYAYQHEDGVEPDLVC
                     VAKALSGGYVPVGATLGKEWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMENE
                     QIVAGARATGELLKSRLAALVDKYELLSEVRGRGLMIGIEF"
     gene            complement(5190..7124)
                     /gene="dxs"
                     /locus_tag="JIX56_RS04610"
                     /old_locus_tag="JIX56_04610"
     CDS             complement(5190..7124)
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329157.1"
                     /locus_tag="JIX56_RS04610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04610"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_257537475.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 3e-112, bitscore:
                     373.4, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.8e-06, bitscore:
                     25.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILESIRQPRDLKALTEAELGELAEEIREFLVHAVARTGGHLGP
                     NLGVVELSVALHRVFESPVDRIVWDTGHQSYVHKLLTGRQDFSKLRGKGGLSGYPSREE
                     SEHDIVENSHASTALGWADGLAKARQVRREKGHVVAVIGDGALTGGMAWEALNNIAAAK
                     DRPLIIVVNDNERSYSPTIGGLANHLATLRTTDGYEQFLAWGKDLLLRTPVVGKEVYEA
                     LHGAKKGFKDAFAPQGMFEDLGLKYVGPIDGHDIKAVESALRRAKRFHGPVLVHCLTQK
                     GRGYEPALANEEDHFHTVGVMDPLTCEPLTPADGPSWTSVFGDEIVRIGDEREDVVAIT
                     AAMLHPVGLGRFAEKFPDRVWDVGIAEQHAAVSAAGLATGGLHPVVAVYATFLNRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGVDGASHNGMWDMSILQVVPGLRIAAPRDAEQLRAQL
                     REAVAVDDAPTLIRFPKESVGPEIPSLERVGGMDVLHRSPSSDRPEVLLVAVGVMASVC
                     LQAAELLETRGIGCTVVDPRWVKPVDPALPWLADEHRLVAVVEDNSRAAGVGSAVALAL
                     GDAEVDVPVRRFGIPEQFLPHAKRGEVLADIGLTPVEIAGRISASLAARDAFAKGDLSE
                     AELSKEKPQ"
     gene            complement(7167..8324)
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="JIX56_RS04615"
                     /old_locus_tag="JIX56_04615"
     CDS             complement(7167..8324)
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031167.1"
                     /locus_tag="JIX56_RS04615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04615"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_257537476.1"
                     /transl_table=11
                     /translation="MTAVSLGVPEMPARPVAERRLTRRIQVGPVAVGGGAPVSVQSMTT
                     TRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALVVIARKSQIPVIADIHFQPKYV
                     FAAIEAGCAAVRVNPGNIKQFDDKVKEIARAAREHGTPIRIGVNAGSLDKRLLLKYGKA
                     TPEALVESALWEASLFEEHDFRDIKISVKHNDPVVMIEAYRQLAARCDYPLHLGVTEAG
                     PAFQGTIKSAVAFGALLSEGIGDTIRVSLSAPPVEEVKVGIQILEALNLRQRRLEIVSC
                     PSCGRAQVDVYRLADEVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQI
                     FVKGEVIKTVPESKIVETLIDEAMKIAEQMEKDGVASGEPAVTVS"
     gene            complement(8329..9351)
                     /gene="hpnH"
                     /locus_tag="JIX56_RS04620"
                     /old_locus_tag="JIX56_04620"
     CDS             complement(8329..9351)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004980252.1"
                     /locus_tag="JIX56_RS04620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04620"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_257537477.1"
                     /sec_met_domain="PF04055 (E-value: 1e-17, bitscore: 64.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.2e-08, bitscore: 33.7,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5.7e-05, bitscore: 22.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIKVATYLAEQKLRKRDKFPLIVELEPLYACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVARKKYVF
                     LCTNAMLLRKKMDDFKPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVAAIKEAKKRGF
                     RVTTNSTFFNTDTPQTIIEVLNYLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFSGGNRRRWRLNHSPLFLDFLEGKVDFPCTAWAIPNYSLFGWQRPCYLMSDGYVT
                     TYRELIEDTDWDAYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAMRETVSGNQG
                     "
     gene            complement(9357..10001)
                     /locus_tag="JIX56_RS04625"
                     /old_locus_tag="JIX56_04625"
     CDS             complement(9357..10001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484604.1"
                     /locus_tag="JIX56_RS04625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04625"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_257537478.1"
                     /transl_table=11
                     /translation="MNAPAAGAPLLIACALGIEQLALRSGDRGGAGGPVTVLRTGMGPR
                     AAERSVTRLLADPGLRDAAVLATGFCAGLAPGMHPGDLVVADETRGPDGAVTPCVGTEL
                     LVKELVRAVPGRTVHTGPLTGSDHVVRGRERSDLFATGALAVDMESAVTLHCAVRSGVR
                     PVAAVRVVMDAPEHELVRISTVRGGISAFRVLRAVLPAYYEWHRSLLLPRR"
     gene            complement(10001..11995)
                     /gene="shc"
                     /locus_tag="JIX56_RS04630"
                     /old_locus_tag="JIX56_04630"
     CDS             complement(10001..11995)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329185.1"
                     /locus_tag="JIX56_RS04630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04630"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_257537479.1"
                     /sec_met_domain="T2TS (E-value: 1.7e-149, bitscore: 498.0,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGAPLPRAAAASDTDHDTPVAAGVQDAAAHAIRRATA
                     YLLSRQDAQGWWKGDLETNVTMDAEDLLLRQFLGIRDEKTTQAAALFIRGEQRQDGTWA
                     TFYGGPPELSATVEAYVALRLAGDDPAEPHMAKASAWIRERGGIAAARVFTRIWLALFG
                     WWKWDDLPEMPPEIVYFPKWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELH
                     TDPGRPNPPKPLEPLGSWEGAFQRLDKLLHGYHKVALKRLRKAAMNSAARWIIERQEND
                     GCWGGIQPPAVYSVIALHLLGYDLQHPVMRAGLESLDRFAVWREDGARMIEACQSPVWD
                     TCLATIALADAGLPADHPQLVKAADWMLGEEIVRPGDWAIKRPQLPPGGWAFEFHNDNY
                     PDIDDTAEVVLALRRVEHHDPERVEKAIRRGVRWNLGMQSRNGAWGAFDVDNTSPFPNR
                     LPFCDFGEVIDPPSADVTAHVVEMLAVEGLSHDPRTRRAIEWLLAEQEPNGSWFGRWGV
                     NYVYGTGSVVPALVAAGLPAAHPAIRRAVSWLETVQNDDGGWGEDLRSYPDPAEWGGKG
                     ASTASQTAWALLALLAAGERDAKATERGIEWLAQTQREDGGWDEPYFTGTGFPWDFSIN
                     YHLYRQVFPLTALGRYVNGEPAVLKTKES"
     misc_feature    complement(12062..12072)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: strong, score: 22.05"
                     /tool="antismash"
     gene            complement(12134..13186)
                     /locus_tag="JIX56_RS04635"
                     /old_locus_tag="JIX56_04635"
     CDS             complement(12134..13186)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484607.1"
                     /locus_tag="JIX56_RS04635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04635"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_257550731.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.5e-58, bitscore:
                     196.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAARTAVDVTALLERGRTLATPVLRAAVDRLAPPMDTVAAYHF
                     GWIDAHGNPADGDGGKAVRPALAVMSAEVTGAAPEVGIPGAVAVELVHNFSLLHDDLMD
                     GDEQRRHRDTVWKVHGPAQAILVGDALMVLANEILLELGTAEAARATRRVTTATRALID
                     GQAQDISYEHRERVTVEECLEMEGNKTGALLACACSIGAVLGGADDRTADTLEKYGYHL
                     GLAFQAVDDLLGIWGDPVSTGKQTWSDLRQRKKSLPVVAALAAGGPASEQLGELLAADA
                     KSSDFENFSEEEFAARAALIEEAGGREWTAEEARRQHGNAIEALDSIRMPDRVRDQFAA
                     LADFVVVRKR"
     gene            complement(13276..14703)
                     /gene="hpnE"
                     /locus_tag="JIX56_RS04640"
                     /old_locus_tag="JIX56_04640"
     CDS             complement(13276..14703)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983091.1"
                     /locus_tag="JIX56_RS04640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04640"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_257537480.1"
                     /transl_table=11
                     /translation="MTDGAQSEGLLDVDGTGRSRSTAVVVGGGLAGITAALSLADAGVR
                     VTLLEGRPRLGGLAFSFQRGDLTVDNGQHVYLRCCTAYRWFLDRVDGAALAPLQDRLDV
                     PVLDAGARPGRRLGRLRRDALPVPLHLGRSLATYTHLSLTERAGVGRAALALKALDLAD
                     PALDERDFGSWLAAHGQSARAVEALWDLVGVATLNAVAQDASLGLAAMVFKTGLLSDPG
                     AADIGWAHVPLGELHDRLARKALDSAGVRTELRTRVTSISPQVNGNWRVEVPGESLDVD
                     AVVLAVPQRETYDLLPEGALDEPGRLLEIGTAPILNVHVVYDRKVLSKPFFAALGSPVQ
                     WVFDRTEASGLSGGQYLALSQSAAQDEIDAPVSALRERYLPELERLLPSTRGAEVKDFF
                     VTRERTATFAPTPGVGRLRPGARTKAPGLYLAGAWTATGWPATMESAVRSGIGAAAAAL
                     SALGRPRDLLFDYEEAA"
     misc_feature    complement(14824..14838)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.38"
                     /tool="antismash"
     gene            complement(14840..15790)
                     /gene="hpnD"
                     /locus_tag="JIX56_RS04645"
                     /old_locus_tag="JIX56_04645"
     CDS             complement(14840..15790)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994383.1"
                     /locus_tag="JIX56_RS04645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04645"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_257537481.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.6e-54, bitscore:
                     184.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.2e-67,
                     bitscore: 226.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTVESEPHASPPVLAAYSYCEAVTGRQARNFAYGIRLLPTPKR
                     RAMSALYAFSRRVDDIGDGALAVEVKAARLEETRALLTRVRDGSVDQDDTDPVAVALAH
                     AGRTFPIPLDALDELIGGVLMDVRGETYETWDDLKVYCRCVAGAIGRLSLGVFGTEPGA
                     RGAERAPEYADTLGLALQLTNILRDVREDALGGRTYLPADDLAKFGCSAGFAGPLPPAD
                     SDFAGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIEREPEAVLR
                     GRVSLPGREKAYVAVRGLSGLDARHVSRRTVRRRV"
     gene            complement(15787..16689)
                     /gene="hpnC"
                     /locus_tag="JIX56_RS04650"
                     /old_locus_tag="JIX56_04650"
     CDS             complement(15787..16689)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484610.1"
                     /locus_tag="JIX56_RS04650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04650"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_257537482.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.9e-39, bitscore:
                     133.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.4e-39,
                     bitscore: 134.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETGTARTGDPERDTLDKAGAENFPVAPFFLPRAWREDLMAVYG
                     FARLVDDIGDGDLAPGGADARLLGVPPQDADDRLLLLDAFEADLHRVFDATPNHPLLRR
                     LQHTVRRHCLTPEPFLALIAANRQDQLVKRYESYDDLLAYCRLSANPVGHLVLAVTGTS
                     TPERVRHSDAICTALQIVEHLQDVTEDLGRDRVYLPAADMKRFHVQEADLAAPTAGASV
                     RALVAYEAERARDLLNEGTPLVGSVHGRLRLLLAGFVAGGRAAVHAITAAEFDVLPGPP
                     KPGKLRLLREVGATLRGEG"
     gene            complement(17121..17897)
                     /locus_tag="JIX56_RS04655"
                     /old_locus_tag="JIX56_04655"
     CDS             complement(17121..17897)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484611.1"
                     /locus_tag="JIX56_RS04655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04655"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_257537483.1"
                     /transl_table=11
                     /translation="MAEALIPTVIADELHIVYRVNGAKTGKGSATAALSRIIKRGSDDA
                     ARGVRKVHAVRGVSFVAYRGEAIGLIGSNGSGKSTLLRAIAGLLPAEKGKVYTDGQPSL
                     LGVNAALMNDLTGERNVILGGLAMGMSREQIRERYQDIVDFSGINEKGDFITLPMRTYS
                     SGMAARLRFSIAAAKDHDVLMIDEALATGDRNFQKRSEARIRELRKEAGTVFLVSHNNK
                     SIRDTCDRVLWLERGELRMDGPTDEVLKEYEKFTGK"
     gene            complement(17890..18819)
                     /locus_tag="JIX56_RS04660"
                     /old_locus_tag="JIX56_04660"
     CDS             complement(17890..18819)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="JIX56_RS04660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04660"
                     /product="ABC transporter permease"
                     /protein_id="WP_257537484.1"
                     /transl_table=11
                     /translation="MSETTHDGRVVVSDRPSPDDGLSATELAAKYGLAVSGARPGLAEY
                     VRQMWGRRHFILAFSQAKLTAQYSQAKLGQLWQVATPLLNALVYFLIFGLILNADRGMS
                     REVYIPFLVTGVFVFTFTQSSVMAGVRAISGNLGLVRALHFPRASLPISFALQQLQQLL
                     FSMIVLFCVAVGFGSYPRLSWLLIVPVLVLQFLFNTGLALIMARMGSKTPDLAQLMPFV
                     MRTWMYASGVMFSIPVMLADHPKWIADILQWNPAAIYMDLMRFALIDGYGSENLPPHVW
                     AVAGGWAVLIALGGFVYFWKAEERYGRG"
     misc_feature    18814..18829
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.99"
                     /tool="antismash"
     gene            complement(18915..19799)
                     /locus_tag="JIX56_RS04665"
                     /old_locus_tag="JIX56_04665"
     CDS             complement(18915..19799)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983096.1"
                     /locus_tag="JIX56_RS04665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04665"
                     /product="glycosyltransferase"
                     /protein_id="WP_257537485.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.2e-14,
                     bitscore: 51.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGGMKVGAVIITMGNRPDELRALLDSVAKQDGDRVEVVVVGNGS
                     PVPDVPEGVRTVELSENLGIPGGRNIGIEAFGPSGRDVDVLLFLDDDGLLAHHDTAELC
                     RKAFEDDPKLGIVSFRIADPDTGETQRRHVPRLRASDPMRSSRVTTFLGGANAVRTQVL
                     AEVGGLPDEFFYAHEETDLAWRALDAGWMIDYRSDMVLYHPTTAPSRHAVYHRMVARNR
                     VWLARRNLPAALVPVYLGAWLLLTLLRKPSGPALRAWFGGFKEGWTSPCGARRPMKWRT
                     VWRLTRLGRPPVI"
     gene            complement(19796..20575)
                     /locus_tag="JIX56_RS04670"
                     /old_locus_tag="JIX56_04670"
     CDS             complement(19796..20575)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="JIX56_RS04670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04670"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_257537486.1"
                     /transl_table=11
                     /translation="MPKPSVAELRPVVHPPGVKDRRSGEHWAGRLYMREISLRIDRHLV
                     NTRVTPNQLTYLMTVFGVLAAPALLVPGITGAVLGVLMVQLYLLFDCVDGEIARWRKQF
                     SMAGVYVDRVGAYLCDAAVLVGFGLRAADLWGTGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQTGKPPVQESASEPRTSGMALARKAAAALKFHRLILGVEASLLILVLAVVDQ
                     ARGDLYFSRLGVAVLAGIALLQTLLHLVSILASSRLK"
     gene            complement(20553..21617)
                     /locus_tag="JIX56_RS04675"
                     /old_locus_tag="JIX56_04675"
     CDS             complement(20553..21617)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="JIX56_RS04675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04675"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_257537487.1"
                     /sec_met_domain="Fe-ADH (E-value: 2.5e-18, bitscore: 65.1,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPIVVDIRPGALDDLATILSDQRIAPSGRMAFAISP
                     GSGAALRDRFAPALPEADWFCDADGTIDGAVRLADSIKKGGHYDAVVGLGGGKVIDCAK
                     YAAARVGLPLVAVATNLANDGLCSPVATLDNDAGRGSYGVPNPIGIVIDLDVIREAPVR
                     FVRAGIGDVICKISAVADWELSSRETGEKVDGLAAAMARQAAEAVLRHPGGVGDDDFLT
                     TLSESLVLCGISMSVAGDSRPASGACHEISHAFDLSFPRRNALHGEQCGLGGAFATFLR
                     GNHDMAGLMAEVLRHHGLPVLPDEIGFTVDEFVQVVEFAPQTRPGRYTILEHLELSTEQ
                     IKDAYADYAKAISS"
     gene            complement(21605..22357)
                     /locus_tag="JIX56_RS04680"
                     /old_locus_tag="JIX56_04680"
     CDS             complement(21605..22357)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="JIX56_RS04680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04680"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_257537488.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.1e-09, bitscore:
                     36.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVGPEGDEESLTVLDLTLG
                     NFAEIGLSEVAIIVGYRKEAVYERREALEAKYGVKITLIDNDKAEEWNNAYSLWCGRDA
                     IKHSVILANGDTVHPVSVEKTLLAARGDGKKIILALDTVKSLADEEMKVVVGPEGGMSK
                     ITKLMDPAEATGEYIGVTLIEGEAADELADALKTVFETDPQQFYEHGYQELVNRGFRID
                     VAPIGDVNWVEIDNHDDLAKGREIACQY"
     gene            complement(22354..24159)
                     /locus_tag="JIX56_RS04685"
                     /old_locus_tag="JIX56_04685"
     CDS             complement(22354..24159)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676195.1"
                     /locus_tag="JIX56_RS04685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04685"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_257550733.1"
                     /transl_table=11
                     /translation="MSTAILTGQPVPGSSLEGDLRSLGFDVRVASGAGDAETLLATVPA
                     GQRVAIVDARFVGHAHALRLGLTDPRFEAAAVPGAVTVRATARPALIRALARESSAASG
                     TTAVAVDNLADRVIAALDADGVTLHRPELGTLVAVVPADPQARNEARQAVADVDDEAVR
                     LRTAVKSRDGFFTTYCVSPYSRYLARWCARRGLTPNQVTTASLITALIAAGCAATGTRG
                     GFVAAGLLLIFSFVLDCTDGQLARYSLQYSTLGAWLDATFDRAKEYAYYAGLALGAARG
                     GDDVWALALGAMVLQTCRHVVDFSFNEANHDATANTSPTAALSGKLDSVGWTVWVRRMI
                     VLPIGERWAMIAVLTAVTTPRITFYALLIGCAFAATYTTAGRVLRSLTRKARRTDRAAR
                     ALADLADSGPLAEALTRIAPSRYAVVARLLALAGAVVVVLTAWFDGPGWTVVFAAAVYV
                     VVSADAVARPLKGALDWLIPPLFRAAEYGTVLVLAAKAEVNGALPVAFGLVGAVAYHHY
                     DTVYRIRGDAGAPPRWLVRAIGGHEGRTLLVTVLAALLAPTDFKVALTALAVAVALLVL
                     LESIRFWVTAHKTGAPAVHDEGEPA"
     misc_feature    24370..24383
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.26"
                     /tool="antismash"
     misc_feature    complement(24393..24406)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.35"
                     /tool="antismash"
     gene            24563..25534
                     /gene="galE"
                     /locus_tag="JIX56_RS04690"
                     /old_locus_tag="JIX56_04690"
     CDS             24563..25534
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (65-182). E-value:
                     4.5e-10. Score: 31.0. Matches aSDomain:
                     nrpspksdomains_JIX56_RS04690_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484619.1"
                     /locus_tag="JIX56_RS04690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04690"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_257537489.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.8e-16, bitscore:
                     59.2, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.8e-08,
                     bitscore: 32.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVAKVMTGAGEQVVTLDDLSAGVPGRLPKSI
                     PLIHGSALDGDLLKRVLAEHAVTGVVHLAARKQVGESVAQPTRYYQENVGALATLLEAS
                     AGAGVRRFLFSSSAAVYGNPDVDLITEDTPCAPMSPYGETKLAGEWLVRAAGEAHGIAT
                     TCLRYFNVAGAAEPALADTGVFNVVPMVFDRLTRDEAPRIFGDDYPTPDGTCVRDYIHV
                     ADLAHAHLAAARHLTAEGGAGDLTVNIGRGEGVSVRELVTLIGEVTGDRRPALVEPRRP
                     GDAPRAVASAALAERELGWTARRGVREMVESAWEGWRLNHGL"
     aSDomain        24758..25108
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JIX56_RS04690_NAD_binding_4.1"
                     /evalue="4.50E-10"
                     /label="JIX56_RS04690_NAD_binding_4.1"
                     /locus_tag="JIX56_RS04690"
                     /protein_end="182"
                     /protein_start="65"
                     /score="31.0"
                     /tool="antismash"
                     /translation="AVTGVVHLAARKQVGESVAQPTRYYQENVGALATLLEASAGAGVR
                     RFLFSSSAAVYGNPDVDLITEDTPCAPMSPYGETKLAGEWLVRAAGEAHGIATTCLRYF
                     NVAGAAEPALADT"
     misc_feature    25566..25580
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.05"
                     /tool="antismash"
     misc_feature    complement(25595..25609)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            25693..26631
                     /locus_tag="JIX56_RS04695"
                     /old_locus_tag="JIX56_04695"
     CDS             25693..26631
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006383714.1"
                     /locus_tag="JIX56_RS04695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIX56_04695"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_257537490.1"
                     /transl_table=11
                     /translation="MGAGHDHGHAHHAPTSGTAAAAYRGRLRIALSITLTVMAVELVGG
                     VLADSLALIADAAHMATDAVGLGMALLAIHFANRPATGNRTFGFARAEILAALANCLLL
                     LGVGGYVLYEAIQRFITPVGTQGGLTVVFGAIGLVANMISLTLLMRGQKESLNVRGAFL
                     EVAADALGSLAVIISATVILLTGWQAADPIASLVIGLMIVPRTVKLLRETLDVLLEAAP
                     KNVDMAEVRAHILALPGVEDVHDLHAWTITSGMPVLSAHVVVGSDTLDSIGHEKMLHDL
                     QGCIGDHFDVEHCTFQLEPGGHAEHEAKLCL"
ORIGIN
        1 tggacgtact gcacggcgct cagccctccc gtcggcggcc tcagccgata gaggtcgccg
       61 cgctgcacga ccggccggat ctccttgtac agctccaccc agtcccgcgc ctcggccagc
      121 tcctcctcgg tccactcggt gaggtcgccg ccgacgccga gcacccccgc catggcactg
      181 acgaagcgga agcgcagcga gctgacccgg ccgttgagct gattgttcgg gctgtcggtg
      241 acccaggcgg ccatgatccg ggccgggtgg acctgactga agccgtgctg gatggcgagc
      301 cggtcgagcg ggtcggtgtt gtccgaggtc cacacctggt ccgtccgcgc catcaccccg
      361 aggtcgatac gaccgccgcc gcccgagcag gactcgaacg ccacccccgg gtgcgcggcc
      421 cgcagccggt ccagcaaggc gtagaaagcg tgcacgtgct cgacccacag cttctgcggg
      481 tacggctcac cgggccagcc ggcatccgtg aagcagcggt tgaagtccca cttcacatag
      541 tcgatcggcg cgctggagag gagcccgttc aactgctccc agagatattc ctgaacatcc
      601 tcgcgcgcga gattgagtac gagctgattg cgcagctccg tccgctttcg tcccggttgg
      661 aactgggccc attcggggtg cgaccggtac aactcgctgt ccggattgac catctcgggc
      721 tcgacccaga taccgaactg cataccgagg gcgtgcacat agtcggcgag cggcgtcagc
      781 cccttcggga agcggtcggg gttgggggtc cagtcaccga gcccggcccg gtcactggtg
      841 cgcgtcccga accagccgtc gtccaccacg aacagctcga cccccatggc cgccgcccgc
      901 cgcgcgagcg tcccctgctg ctcctccgag atgtcgaact cggtggcttc ccaggagttg
      961 aagagcaccg gccggtcctg atccgcgtcc gggatgacgt acgtccgctg gtacgtgtgc
     1021 caggcgcggc tcgccccgcc gaagccgccg tcgctccaca ggccggcgaa gagcggcgtg
     1081 gtgaacgtct cgcccgtctc cagccgcagc agaccggact cgtcgtatcc ggcgcccccg
     1141 gtgatctgca cgcgcgcgtc cgggagttgg gcgaccgcga tccgccagga ccccgaccag
     1201 ccgagggcgc agccgtagac ctcgccgcgc tcctcggtgg cgtcggtgtc gagggcgacc
     1261 cagggcagat gctggtgccc ggtgtggccg cgccgactgc cgatgacctt ctcgccgtag
     1321 gtgaggtccc cgcgcacgag ccgggactcg gccgcccatc gcccgtgcag ctgggacagc
     1381 cgccaggcct cctcgcgccg cggcagcgtc caggtcgccg agtcggcccg cagcagctcc
     1441 accgccggtc cttcattggc gagggtcacc cagcgctcga tcacgtcgtc gcgcatccgg
     1501 tagtgcaggg tgatgccgag gccgtcgtcg gtgaaccgca gccgcagctc gtcgccgtcg
     1561 gcctcgtact cctggaaggt ccactcggtg ccgcgccgct cgtccgtgcg cacggagagg
     1621 gcggggcggg tgaagcgggg gccgccctcg acggggtact cctcgtgccc gtcgaccggg
     1681 gcctcgaacg gccagtacgg cagctgctgc cggccggcca gttcctcggc gtcggcgagt
     1741 gcgatccggg gaccccagtg cagatgcagc agctcgtcat tctccgtgag ccgcagggca
     1801 tagctgctcc tgggccccgt aagaagccag gtacggcctt cggcgccgat ttccaacatc
     1861 aggttcccca cagattcgaa caggtgcgat cgggcttcaa catcatcgca ggtcgccgca
     1921 ggcgctcacg gcacctgtgg acaactgccg acggggcctt cgcgacacct gtggacaact
     1981 gccgcgggcc gtgccgcggc ccctgtggac aactcattgg cgtacgcacc catgtcgtat
     2041 cgtcgagggc gcgcctcggt gccgagtgcg tgcccgtcga cgatcggcgc cggcggccgg
     2101 atgggaggag ccccagtgac gcagcaggtc ccgtcgaccg agcccgagct gaccggagtg
     2161 cgcaacttcc gcgatgtggg cggtctgccg accgtggacg gccgtcgggt gcgccacggg
     2221 gtgctgttcc gcagtggtca cctcgcgcac gccaccgacg aggacaccgc gttcctggcc
     2281 tccctcggcc tgcacacggt cttcgacttc cgcaacgcgg ccgatcagaa gctggagggc
     2341 ccggatgtcg agttgcccgg cgtgctcaat gtgaatctgc cgctcagcga ccccgcggac
     2401 ggcgccgagt tctggaagat ggtccgcgac ggcgatctgg accagctgcg tgcgctgctc
     2461 gacgacggca aggcggccgg ccggatgatc gcctcctacc ggacgatcat caaggaccgc
     2521 acggccgagc actcccgtgt gctgcacgcg ctggccgagg acagcgtgcc cgcgctgatg
     2581 cactgcgcgg cgggcaagga ccgagcgggc ctctccatcg ccatcaccct cctcaccctg
     2641 ggcgtcgagc gcgaggccat cgtcgccgac tacctggagt cgaacgccaa gcaccgccgt
     2701 tacaaggtgc accgcagcag cacctccgcg agcgcctact ccccggaggt catggagctc
     2761 ctgagcccgc tgttcgacgc ccgcgccgag tacctccaga cggccttcga cacggtcgag
     2821 gagacctggg gtgatgtgga cacctatctg gagcagggcc tgaagatgac cccgcagacc
     2881 cgggagcggc tgcgcgagcg actgctcgac taggcgaccg gcccacgcgg accacgcact
     2941 tactgcttgg cacccacctc gaacagcagg tagacgaagg ccgcgaagag atggccgacc
     3001 gcgatgtaga tgatgagccg cacccacagg gcgcggggga acttctcttc caggtcggtc
     3061 atggggtctc tccaggagtg gtcggcccga ggcacagcgc ggcggtcggg ctctgcagca
     3121 gggtgtggac gaacaggagg tcggcgccgt cgcggtcggc ggcggcgatg cggtgcggtg
     3181 tcagcgagtc gaagtgcgcg ctgtccccgg gcgcgaggag atgcgtggtg tccccgaggc
     3241 gcagccgcag ccgccccttc aggacgtaca gccactcctc accgggatgc acgcgcacga
     3301 tgtcgccctg tgagccgtac ggcacatgga cgcgcagcgc ctgcatcccg cgcccgggcg
     3361 cgcccgcctg ccagtacgtc cagccgccgg ccttggtggg ttccctgtcg gacgcgcgga
     3421 gtacggcgtc ccgttcgggg acgctctcgc cgagcagtgc cgagacggtc gttccataga
     3481 tacgggccag tgcgagcagc atcggcagcg agggctggcg ctgcccggtc tccagccggg
     3541 agaggtgcgc gggcgacagc ccggcggcgc gggccgctgc ctccagggtg agggaggccc
     3601 ggcggcgcag cgcgcgcaac tgcggagcga cgacgggcag ttccccgtcc atcgggggct
     3661 cgggagggtg cgtaccctcg gaagggctca tgcctccatt cagccggagc cttgccccag
     3721 gggcaaattt cttgcctcag aggcaaagcc cagcgaggcc ccaccaccgg cggcccgtgc
     3781 gcactaccgg ttggccaccg cctgcttgac gagcgtcttg ccgaagtccc acatcagtcc
     3841 gcccccgctg tgcgcgtcgt ccatcacctc ggtgaaggcc tcgacgaagc ggtccacctc
     3901 ccgctccccg atgaccagcg gcgggatcag cttgatcacc tccagatggt cgccggagac
     3961 ctgggtgagg atgcggtggc gttgcagcag cggcacgacg accatctggg cgaacagccc
     4021 cttgcgggcc gcctgaagca tcgtccaacg gctgcgcagc ttcagcgacc tgggcctgcc
     4081 gaactcgatg ccgatcatca ggccccggcc gcgtacctcg ctgagcagct cgtacttgtc
     4141 gaccagtgcc gcgagccggc tcttcagcag ctccccggtg gcccgggcac ccgccacgat
     4201 ctgctcgttc tccatgaccg agaggacggc gagcccggcg gccatggcct gggcgttgga
     4261 cccgaagctc gccgaatgga cgaggacacg gtccatggac gagtagacct tcttgaagat
     4321 ccactccttg ccgagggtcg ccccgaccgg gacatagccg ccggagagcg ccttcgccac
     4381 gcacacgagg tcgggctcga ccccgtcctc gtgctggtag gcgtagaagt ccccggtccg
     4441 cccgagcccg gtctgcacct cgtcgacgat cagcagcgcc ttgtgccggt gcagcaactc
     4501 ctgggcggcg cgcagatatc cgggcggcgc ctcgtgcacg cccttgccct ggatgggctc
     4561 gacgacgagc gcggcgacat cgcctttctc caactcccgt gcgagggcgt cgagatcacc
     4621 gagcgggacg gccgtgtcgg gcagcagcgg tgcgaagccg tcccggaagc cggcctcgcc
     4681 gttcacggac agcgagccgg tggtgagccc gtggaaggcg tggtcgcagt agaggacgcg
     4741 tggtctgccg gtggcgtacc gggcgaactt cagcgcggtc tcgacggctt cggtgccgct
     4801 gttgccgaag aacacccgat ccaggtgcgg actgtgggtg agcagcttct cggccagcag
     4861 cccgggcagt ggctggcagt cgaagcgggt caggtcggcg agccgcgcgt cgagcacgtc
     4921 gtgcagcgcc ttgcggacca cggggtggtg gcggccgagc cccatcaccc cgaaccctgc
     4981 gagcatgtcc aggtagtcgt caccgttcgc gtcccagaag tacgcgccct cggcccgctc
     5041 gtagaccttg tcgaagccga tggtgtgcag catgcgcggg agttggtggt tgaggtgccg
     5101 ggcgtggagt tcgtagcgct cggcaccgcg ttcggcgagg agtctgccga ggtcgaactc
     5161 ctcggttccg gcggcgggtt ccacggtggt cattgcggtt tctccttgga aagctcggcc
     5221 tcggacaggt cccccttcgc gaacgcgtcc ctggcggcca gcgaggcgct gatccgcccg
     5281 gcgatctcga ccggcgtgag acctatgtcc gccagcacct caccgcgctt ggcgtgcggc
     5341 aggaactgct ccggaatccc gaaccgcctt acgggtacgt cgacttcggc gtcccccaga
     5401 gcgagagcga ccgccgaacc gaccccggcg gcccggctgt tgtcctccac gacggccacc
     5461 agccggtgtt cgtcggcgag ccacggcagc gccggatcga ccggcttgac ccagcgcgga
     5521 tccacgacgg tgcagccgat gccccgcgtc tccagcagct cggcggcctg cagacacacc
     5581 gacgccatca cgccgacggc gaccagcagc acctccggac ggtccgagga cggggagcgg
     5641 tgcaggacgt ccatgccgcc cacccgctcc agggagggga tctccggccc caccgactcc
     5701 ttggggaacc ggatcagcgt gggagcgtcg tcgacggcga ccgcctcccg cagctgcgcc
     5761 cgcaactgtt cggcgtcacg cggcgcggcg atccgcagcc ccggcacgac ctggaggatc
     5821 gacatgtccc acataccgtt gtgtgacgca ccgtcaacac ccgtcacccc ggcccggtcc
     5881 aggacgaagg tgaccccgca ccggtgcagc gccacgtcca tcagcagctg gtcgaaggcc
     5941 cggttgagga aggtcgcgta gaccgccacg accggatgga gcccgccggt ggcgaggcct
     6001 gccgccgaca ccgccgcgtg ctgctcggcg atcccgacgt cccacacccg gtcggggaac
     6061 ttctccgcga acctgccgag ccccaccgga tgcagcatgg ccgccgtgat cgcgacgacg
     6121 tcctcgcgct cgtccccgat ccgtacgatc tcgtcgccga agaccgaggt ccaggacggt
     6181 ccgtcggccg gtgtgagcgg ttcgcaggtc agcgggtcca tgacgccgac cgtgtggaag
     6241 tggtcctcct cgttggcgag cgcgggctcg tacccgcgcc ccttctgcgt caggcagtgg
     6301 accagaaccg gcccgtggaa gcgcttggcg cgccgcagcg ccgactcgac cgccttgatg
     6361 tcgtgcccgt cgatcgggcc gacgtacttc aggcccagat cctcgaacat gccctgcggc
     6421 gcgaacgcgt ccttgaagcc cttcttcgcc ccgtgcagtg cctcgtagac ctccttgccg
     6481 acgaccggag tgcgcagcag gaggtccttg ccccaggcga ggaactgctc gtagccgtcg
     6541 gtggtccgca gggtcgcgag gtggttggcg aggccgccga tggtcgggga gtacgagcgc
     6601 tcgttgtcgt tgacgacgat gatcagcggc cggtccttgg cggccgcgat gttgttcagt
     6661 gcctcccagg ccatgccgcc ggtcagcgcg ccgtcgccga tgaccgcgac cacatggccc
     6721 ttctcccgcc gcacctgccg ggccttggcg aggccgtccg cccagccgag ggcggtggag
     6781 gcgtgactgt tctcgacgat gtcgtgctcg gactcctcgc gcgacggata gccggacaga
     6841 ccgcccttgc cgcgtagctt ggagaagtcc tgacgccccg tcagaagctt gtgcacatag
     6901 ctctgatgac cggtgtccca gacgatgcgg tcgacgggtg actcgaagac ccggtggagt
     6961 gcgacggaga gttccaccac ccccagattg ggccccaggt gaccaccggt cctggcgacc
     7021 gcgtgcacca ggaactcccg tatttcctcg gccagttcac cgagttccgc ctcggtcagc
     7081 gccttcaggt cgcgcggttg ccggatgctc tccagaatcg tcacgtcggg ccccctctcg
     7141 atccgtgctc tcttaagccc gtgttgtcag ctcacggtga ccgccggctc ccccgacgcg
     7201 acgccgtcct tctccatctg ctcggcgatc ttcatcgcct cgtcgatgag ggtctccacg
     7261 atcttcgact cggggacggt cttgatgacc tcgcccttca cgaagatctg ccccttgccg
     7321 ttgccggagg cgacccccag gtccgcctcc cgcgcctccc cgggtccgtt gacgacgcag
     7381 cccatgacgg ccacccgcaa cggcacctcc atgccctcga gaccggcggt cacctcgtcc
     7441 gccagccggt acacatctac ctgggcccgc ccgcacgacg gacacgacac gatctccagc
     7501 cgccgctgcc gcaggttcag cgcctcaagg atctggatgc cgaccttgac ctcctcgacg
     7561 ggcggagcgc tgagcgacac ccggatcgtg tcgccgatcc cctcgctcag cagcgccccg
     7621 aaggcgacgg cggacttgat cgtgccctgg aacgcgggcc cggcctccgt gacgcccaga
     7681 tgcaacggat agtcgcaccg ggcggccagc tgccggtacg cctcgatcat cacgaccggg
     7741 tcgttgtgct tgaccgagat cttgatgtcc cggaagtcgt gctcctcgaa cagcgacgcc
     7801 tcccacagcg cggactccac cagtgcctcg ggcgtcgcct tgccgtactt cagcaggagc
     7861 cgcttgtcga gcgagccggc gttgaccccg atccggatcg gcgtcccgtg ctccctcgcc
     7921 gctcgggcga tctccttcac cttgtcgtcg aactgcttga tgttgcccgg gttcacccgc
     7981 acggccgcac atccggcctc gatcgccgcg aacacgtact tcggctggaa gtggatgtcc
     8041 gcgatcaccg ggatctgcga cttgcgggcg atcaccacaa gcgcgtcggc gtcgtcctgc
     8101 gtgggacacg cgacccggac gatctggcag ccggacgcgg tgagctccgc gatctgctgc
     8161 agggtggcgc cgatgtccga cgtacgggtc gtcgtcatcg actgcaccga caccggggcc
     8221 ccgcccccca cggccaccgg accgacctgg atccgccgcg tcaggcggcg ctccgcgacc
     8281 ggtcgggcag gcatctcggg cacgcccagc gacacggcgg tcatcacatc acccctggtt
     8341 cccggagacg gtctcacgca tggcgcgcag ggactccttc agcgagccca tggtggcgag
     8401 gacggcggtc ggctcgtagc cgcagtgcgc catgcagttg gcgcagcgcg ggtccttgcc
     8461 ccggccgtac gcgtcccagt cggtgtcctc gatcagctcc cggtacgtcg tgacgtaccc
     8521 gtcgctcatc agatagcagg gcctctgcca gccgaagagc gagtagttcg ggatcgccca
     8581 cgccgtgcac gggaagtcga ccttgccctc caggaagtcg aggaacaggg gcgagtggtt
     8641 gaggcgccag cgccgccggt tgccgcccga gaaggccttc ttgaacagtt cgcgggtctg
     8701 ctcgacgccg aggaagtgct cctggtcggg ggccttctcg taggcgtagg cgggcgagat
     8761 catcatctcg tcgaccttga ggtcgtcgtt gaggtagttg agcacctcga tgatggtctg
     8821 cggcgtgtcg gtgttgaaga aggtcgagtt ggtggtcacc cggaagcccc gcttcttggc
     8881 ctccttgatg gcggccacgg cctcgtcgaa cacgccctcc ttcgccaccg actcgtcgtg
     8941 ccgctcccgc agcccgtcga tgtgcacggc gaacgcgaag tacggcgagg gcttgaaatc
     9001 gtccatcttc ttgcgcagca gcatcgcgtt ggtgcacagg aacacatact tcttcctggc
     9061 caccaactgg cgtacgatct cgtcgatctg agggtgcatc aggggctcgc cgcccgcgat
     9121 cgacaccatc ggcgcacccg actccaggac ggcgcccacg gcctgcgcca ccggcatgcg
     9181 ctgcttgagc acgcccgccg ggtgctggat cttgccgcag ccctcgcact tcagattgca
     9241 ggcgtagagc ggttccaact cgacgatcaa cgggaacttg tcccgcttgc ggagcttctg
     9301 ttcagcgaga tacgtcgcca ccttgatgga ctggcggagc ggcatggcca tctggctcac
     9361 ctcctgggga gcagcaaaga acggtgccat tcgtagtagg cgggaagaac ggcacggagg
     9421 acgcggaagg ctgatattcc accgcgtacc gtgctgatcc ggaccagctc atgttctgga
     9481 gcgtccatga ccacccggac ggccgcaacc gggcgtacgc ccgatctcac agcgcagtgg
     9541 agtgtgaccg ccgattccat gtcgaccgcg agtgcgccgg tcgcgaacag atcggaccgt
     9601 tcccgaccgc gtacgacgtg atcggatccg gtgagcgggc cggtgtggac cgtgcgcccg
     9661 ggcacggccc gcaccagctc cttgaccagc agttcggtgc ccacacaggg cgtgacggcg
     9721 ccgtcggggc cccgggtctc gtcggcgacc accaggtcac cggggtgcat gcccggggcg
     9781 agtccggcgc agaacccggt ggccagcacg gccgcgtcac gcagccccgg atcggcgagc
     9841 agtcgggtga cggaccgctc ggcggccctc ggccccatgc cggtgcgcag tacggtgacc
     9901 gggcccccgg cgccgccccg gtcaccgctg cgcagggcga gctgctcgat gccgagcgcg
     9961 caggcgatca gcagcggggc cccggcggcg ggcgcgttca tcagctttcc ttggttttca
    10021 ggacggccgg ctcgccgttg acgtaccggc cgagtgcggt gagcgggaag acctgccggt
    10081 agaggtggta gttgatcgag aagtcccagg gaaagccggt gccggtgaag tacggctcgt
    10141 cccagccgcc gtcctcccgc tgggtctggg cgagccactc gatgccgcgc tcggtggcct
    10201 tggcgtcccg ctcccccgcc gccagcagcg cgaggagcgc ccacgcggtc tgggaggcgg
    10261 tggaggcgcc cttgccgccc cattcggcgg ggtcggggta ggagcgcagg tcctcgcccc
    10321 agccgccgtc gtcgttctgc acggtctcca gccaggacac ggcccggcgg atcgcggggt
    10381 gcgcggcggg cagtccggcg gccaccagcg cggggaccac cgagccggtg ccgtagacgt
    10441 agttgacgcc ccagcggccg aaccacgagc cgttcggctc ctgttcggcg agcagccact
    10501 cgatggcgcg ccgggtgcgc ggatcgtggg acagcccctc gaccgccagc atctccacca
    10561 catgcgcggt gacgtcggcg gacggcgggt cgatcacctc gccgaagtcg cagaacggca
    10621 gccggttggg gaacgggctg gtgttgtcga cgtcgaaggc gccccaggcc ccgttcctcg
    10681 actgcatacc gaggttccag cgcaccccgc gccggatggc cttctcgacg cgttccgggt
    10741 cgtggtgttc gacccggcgg agcgccagta cgacctcggc ggtgtcgtcg atgtcggggt
    10801 agttgtcgtt gtggaactcg aacgcccagc cgccgggcgg cagttgggga cgcttgatcg
    10861 cccagtcgcc gggccggacg atctcctcac cgagcatcca gtcggcggcc ttgacgagtt
    10921 ggggatggtc ggcgggcagt cccgcgtcgg cgagggcgat ggtggcgaga caggtgtccc
    10981 acaccggcga ctggcaggcc tcgatcatcc gggccccgtc ctcgcgccac acggcgaacc
    11041 ggtcgaggga ctccaacccg gctcgcatca cggggtgttg gaggtcgtag ccgagcaggt
    11101 gcagcgcgat gaccgagtag acggcgggag gctggatgcc gccccagcag ccgtcgttct
    11161 cctgccgctc gatgatccag cgggccgcgc tgttcatggc cgccttgcgc agccgcttca
    11221 gcgccacctt gtgatagccg tgcagcagct tgtcgagtct ctggaaggcg ccttcccaac
    11281 tccccagcgg ctccaggggc ttgggcgggt tcggtcgccc cgggtcggtg tgcagctcgt
    11341 cgagcgggaa cggtgcgggc cgtaccgggc gcttcgccga gacgacggtc agcggcacga
    11401 tcgtctggcg ggcccagcat ccgaagtcgt agatgttcag cggcatccac ttggggaagt
    11461 agacgatctc cggcggcatc tccggcaggt cgtcccactt ccaccatccg aacagggcga
    11521 gccagatgcg ggtgaagacc cgggcggcgg cgatcccgcc ccgctcccgg atccacgcgg
    11581 acgccttcgc catgtgcggc tcggccgggt cgtccccggc cagccgcagc gcgacgtacg
    11641 cctcgacggt ggcggagagt tcgggcgggc ccccgtagaa ggtggcccag gttccgtcct
    11701 gccgctgctc gcctctgatg aagagggcgg cggcctgggt ggtcttctcg tcccggatgc
    11761 ccaggaactg acggagcagc agatcctcgg cgtccatggt gacgttggtc tccaggtcgc
    11821 ccttccacca gccctgggcg tcctgtcggg agagcaggta ggcggtggcg cgccgtatgg
    11881 cgtgcgcggc ggcgtcctgg acccctgccg ccaccggggt gtcgtggtcg gtgtcgctgg
    11941 ccgcggcagc gcggggcagc ggtgccccgg tgcttccgtc ggtcgtcgct gtcatggctt
    12001 ccccttcgtg cagtggacgg atctctctgc ggtgggtcag ccgtcggccg gtgcatgtcc
    12061 ggtgacatgg caccggccgg cgactacgcg agggctattc gaccgatagt ggtcggcttc
    12121 tgagggatgg cgatcatctc ttccgtacga cgacgaagtc ggcgagtgcc gcgaactggt
    12181 cccgcacccg gtcgggcatc cggatcgagt ccagtgcctc gatggcgttt ccgtgctggc
    12241 ggcgggcttc ctcggcggtc cactcccggc cgcccgcctc ctcgatgagg gcggcgcgcg
    12301 cggcgaactc ctcctcggag aagttctcga agtcgctgct cttggcgtcg gcggcgagaa
    12361 gctcgccgag ctgctccgag gcggggccgc cggccgcgag ggcggccacg accggcaggg
    12421 acttcttgcg ctggcgcaga tcgctccagg tctgcttgcc cgtggagacc gggtcgcccc
    12481 agattcccag caggtcgtcg acggcctgga aggcgaggcc gaggtggtag ccgtacttct
    12541 ccagtgtgtc ggcggtgcgg tcgtccgcgc cgccgaggac cgcgccgatg gagcaggcgc
    12601 aggcgagcag ggcgccggtc ttgttgccct ccatctccag gcactcctcg acggtgaccc
    12661 gctcgcggtg ctcgtaggag atgtcctggg cctgcccgtc gatgagcgcg cgggtcgccg
    12721 tggtgacgcg gcgggtggcg cgggccgcct cggcggtgcc gagttcgagg aggatctcgt
    12781 tggcgaggac catcagggcg tcgccgacga ggatggcctg ggcggggccg tgcaccttcc
    12841 agacggtgtc gcggtggcgg cgctgttcgt cgccgtccat caggtcgtcg tgcagcagcg
    12901 agaagttgtg caccagctcc accgcgaccg cgccggggat gccgacctcg ggtgcggcgc
    12961 cggtgacctc ggcggacatg acggcgagcg cgggacgtac ggccttgccg ccgtcgccgt
    13021 ccgccgggtt gccgtgggcg tcgatccagc cgaagtggta ggcggcgacg gtgtccatgg
    13081 ggggcgccag ccgatcgacg gccgcccgca gcacgggggt ggccagggtc cgcccgcgct
    13141 ccaggagcgc ggtcacgtcc accgcggtcc tcgcagcggc cgtcacggcc gggggcacag
    13201 tgggcacagt ctctccagat gtcgatgtgt tcgcggtacc gagagcgcgg gaaccggtcc
    13261 ggtgcgcttc gagcgtcacg ctgcctcctc gtagtcgaag aggagatctc ggggccggcc
    13321 cagagcggac agtgcggcgg ccgccgcacc gataccgctg cggaccgcgc tctccatggt
    13381 cgcgggccac ccggtggcgg tccacgctcc ggccaggtac aggccggggg ccttggtgcg
    13441 ggcgccgggc ctgagccgtc cgacgccggg ggtgggggcg aacgtcgcgg tacgctcccg
    13501 ggtcacgaag aagtccttca cctccgcgcc gcgcgtggag ggcaacagcc gctccagctc
    13561 gggcagatac cgctcgcgca gtgccgacac gggcgcgtcg atctcgtcct gcgcggccga
    13621 ctgcgacagc gccaggtact ggcccccgct cagcccggac gcctcggtcc ggtcgaagac
    13681 ccactgcacc ggggagccga gcgccgcgaa gaacggcttg ctcagcacct tccggtcgta
    13741 caccacatgg acgttgagga tcggcgcggt gccgatctcc agcagccgcc cgggctcgtc
    13801 gagcgcgccc tcgggcagca ggtcgtacgt ctcgcgctgc ggcacggcga ggacgaccgc
    13861 gtcgacgtcg aggctctcac cgggcacctc gacccgccaa ttcccgttca cctgggggga
    13921 gatggaggtg acgcgagtac ggagttcggt acggacgccc gccgagtcga gcgccttgcg
    13981 ggccagccgg tcgtgcagtt ctcccagcgg gacatgggcc cagccgatgt cggccgcacc
    14041 cgggtcggac agcagacccg tcttgaacac catcgcggcg agccccaggg aggcgtcctg
    14101 ggccaccgcg ttgagggtgg cgacccccac gaggtcccac agtgcctcga cggcacgcgc
    14161 cgactggccg tgcgcggcca gccagctgcc gaagtcccgt tcgtccagcg cgggatccgc
    14221 gaggtcgagc gccttgagcg ccagtgcggc acgccccact ccggcgcgct cggtgagcga
    14281 gagatgggtg tacgtggcca ggctgcgccc cagatgcagg ggtacgggca gcgcgtcgcg
    14341 ccgcagtctg ccgagccgcc gcccgggcct tgccccggcg tcgagaaccg gcacgtcgag
    14401 acgatcctgc agcggtgcga gcgcggcgcc gtccacgcgg tcgaggaacc agcggtaggc
    14461 ggtgcagcac cgcagataca catgctgtcc gttgtcgacg gtcagatcgc cgcgctggaa
    14521 ggagaaggcg agcccgccga ggcgcggccg cccttccagg agagtgaccc gcacgccggc
    14581 gtcggcgagc gagagcgcgg cggtgatgcc cgccagcccc ccgccgacca ccacggccgt
    14641 gctccgggag cggcccgtac cgtccacgtc cagcagtccc tcggactgtg cgccgtcggt
    14701 catcgtgcac cctcccctgc cggtccgccg gggtgtcgga tcggcctgcg gcagaccgtc
    14761 gcagtcaggg acgcctccat gtcgcggagg gttgcgtacc acttttcccc gatgggttcg
    14821 ccttggaccg gattgtccat cagacacgcc tcctgacggt acggcgcgac acatggcggg
    14881 cgtccagacc ggacaggccg cgtacggcga cgtaggcctt ctcgcggccg ggcagcgaga
    14941 cccggccgcg cagcacggcc tccggctcgc gctcgatgcg gtcgagcagc cgtcggtaga
    15001 tgccggccat ggcggcgaca caggcaccgc tgcgccggtc gagcatcggc agcaggcggt
    15061 agccctcggc gaagagggcg cgggcccggc gcacctcgaa gtgcaccaga cccgcgaagt
    15121 cggagtcggc cggcgggagc ggcccggcga acccggccga gcagccgaat ttcgcgaggt
    15181 cgtcggcagg cagataggta cggccgccca acgcgtcctc ccgaacgtcc ctgaggatgt
    15241 tggtgagttg gagtgcgagc ccgagggtgt ccgcgtactc cggcgcgcgt tccgcgccgc
    15301 gcgcccctgg ttccgtgccg aagacgccga gcgagagccg cccgatggca ccggcgacac
    15361 agcggcagta gaccttcagg tcgtcccagg tctcataggt ctcgccgcgt acgtccatga
    15421 ggacaccgcc gatgagttcg tcgagggcgt cgagcgggat cgggaaggtc cgcccggcgt
    15481 gggcgagggc caccgcgaca gggtccgtgt cgtcctggtc gacggagccg tcccggaccc
    15541 gggtgagcag cgctctggtc tcctccagcc gggccgcctt gacctcgacg gcgagcgctc
    15601 cgtcaccgat gtcgtcgacg cgccgggaga acgcgtacag cgcggacatc gcgcggcgct
    15661 tgggtgtcgg cagcagtctg atgccgtagg cgaagttgcg ggcctgccgc ccggtgacgg
    15721 cctcgcagta gctgtaggcg gcgagtaccg gtggggacgc gtgtggttcc gactccacag
    15781 tccggatcac ccctctcctc gcagggtcgc gcccacctcg cgcagcagcc ggagcttgcc
    15841 gggcttgggc gggccgggaa gtacgtcgaa ttcggcggcg gtgatcgcgt ggacggccgc
    15901 ccttcctccc gccacgaacc ccgcgaggag cagcctcagc ctgccgtgga cgctacccac
    15961 gaggggggtg ccctcattca ggagatcacg ggcgcgttcc gcctcgtacg cgaccagcgc
    16021 gcgcaccgat gcgcctgctg tgggagcggc gaggtccgcc tcctggacgt gaaagcgctt
    16081 catgtccgcg gcgggcagat agacacggtc gcggcccagg tcctcggtca cgtcctggag
    16141 gtgttcgacg atctgcaggg cggtgcagat cgcgtcggag tgccggaccc gctcgggggt
    16201 gctggtgccg gtgacggcga ggaccaggtg gccgaccggg ttggcggaca gccggcagta
    16261 ggcgagcagg tcgtcatagc tctcgtaccg cttgaccagc tggtcctggc ggttggcggc
    16321 gatcagggcg aggaacggct ccggggtgag gcagtggcgg cggacggtgt gctggagtct
    16381 gcgcagcagt gggtggttcg gggtggcgtc gaagaccctg tggaggtcgg cctcgaaggc
    16441 gtcgaggagg agcagccggt cgtcggcgtc ctgcgggggg acgcccagga ggcgggcgtc
    16501 ggcgccgccg ggggcgaggt cgccgtcgcc gatgtcgtcg acgaggcggg cgaagccgta
    16561 gacggccatc aggtcctcgc gccaggccct gggcagaaag aagggggcga cggggaagtt
    16621 ctcggcgccg gccttgtcga gggtgtcgcg ctccgggtcc ccggtgcgcg ccgtcccggt
    16681 ttcggtcacc gcccgtcacc cggcgcggga acggcagaag cgtggttgag ctggggagtc
    16741 tccgtagcca tggccgtcac atctcccgtt ctacactgcc tacccaatac gcactatttc
    16801 ggacacgccg cccagtgggc ggcgtctgcg gctgatgccg ggtgtcgcgc attatggacc
    16861 cacttgccgc gattcggcac cggtacagct tacgttgtac aacgccccat gctccgtcgg
    16921 ggtgtcctgc acatcacaag aacgcaccga ttgcccccaa gattcctatg ggtggccgga
    16981 gttgacgctt ccttgccgga gttggcgatt cctttgcgga tgccgggctc cggcctccct
    17041 caaggacgcc gcgtcccggt atcccttgca gacgccgggc cccgccggag cagttccagc
    17101 ggggcccggg tcgtctcgga ctacttgccc gtgaacttct cgtactcctt cagaacctcg
    17161 tcggtcgggc cgtccatgcg cagctcgccg cgttccagcc acaggacacg gtcgcaggtg
    17221 tcgcggatcg acttgttgtt gtgactgacc aggaagaccg tgccggcctc cttgcgcagc
    17281 tcgcggatgc gggcctcgga gcgcttctgg aagttgcggt caccggtggc gagggcctcg
    17341 tcgatcatca ggacgtcgtg gtccttggcc gcggcgatgg agaaccgcag acgggccgcc
    17401 atgccggagg agtaggtgcg catcggcagg gtgatgaagt cgcccttctc gttgatgccg
    17461 gagaagtcga cgatgtcctg gtagcgctcc ctgatctgct cgcgggacat gcccatcgcg
    17521 aggccgccca ggatgacgtt ccgctcgccc gtgaggtcgt tcatcagggc ggcgttgacg
    17581 ccgagcaggg agggctggcc gtcggtgtag accttgccct tctccgcggg gagcaggccg
    17641 gcgatggcac gcagcagggt ggacttgccg gagccgttgg agccgatcag gccgatggcc
    17701 tcaccgcggt aggcgacgaa ggagacaccc ctgacggcgt gcaccttgcg cacaccccgc
    17761 gccgcgtcgt cggagcctcg cttgatgatg cggctgaggg cggcggtggc gctgcccttg
    17821 ccggtcttgg cgccgttgac gcggtagacg atgtgcagtt cgtccgcgat gacggtgggg
    17881 atgagtgcct cagccacggc cgtacctctc ctccgccttc cagaagtaca cgaagccgcc
    17941 gagcgcgatc agtacggccc agccgccggc gaccgcccac acgtgcgggg gcaggttctc
    18001 cgagccgtag ccgtcgatca gcgcgaaacg catcaggtcc atgtagatcg cggccgggtt
    18061 ccactggagg atgtcggcga tccacttggg gtgatcggcg agcatcaccg ggatggagaa
    18121 catgacgccg gaggcgtaca tccaggtccg catcacgaac ggcatcagct gcgcgaggtc
    18181 cggggtcttg gaacccatgc gggccatgat cagcgcgagg ccggtgttga acaggaactg
    18241 cagcaccagc acggggacga tcagcagcca ggacagccgc ggatagctgc cgaagccgac
    18301 cgcgacacag aacagcacga tcatcgagaa cagcaactgc tggagctgct ggagcgcgaa
    18361 ggagatgggc agcgaggcac gcgggaagtg cagggcgcgc accaggccga ggttgccgga
    18421 gatcgcacgg acgcccgcca tcaccgagct ctgtgtgaag gtgaagacga acacacccgt
    18481 gaccaggaac gggatgtaga cctcgcgcga catgccccgg tcggcgttga ggatcaggcc
    18541 gaagatcagg aagtacacga gcgcgttgag cagcggagtg gccacctgcc acagctggcc
    18601 gagcttggcc tggctgtact gcgcggtgag cttcgcctgg gagaaggcga ggatgaagtg
    18661 ccgtcgcccc cacatctggc ggacgtactc ggcgagtccg ggccgggcgc cgctcacggc
    18721 gagcccgtac ttggcggcca gttccgtggc ggagagcccg tcgtcgggcg acggacggtc
    18781 gctcaccaca accctgccgt catgcgttgt ctcactcaca aatggaaact ttcgtcctca
    18841 aagtgcgcag cctggtcggg ccgaggtaga aacctggacc gggtacggcc gaatgctctc
    18901 agatttcgag cttgtcagat gacgggaggt cggcccagtc gggtcagccg ccacaccgta
    18961 cgccacttca tggggcggcg ggcgccgcag gggctcgtcc agccctcctt gaagccgccg
    19021 aaccaggctc tcagggccgg gccggagggc ttgcggagca gggtcaggag cagccaggcg
    19081 cccaggtaga ccgggacgag ggcggccggg aggttacggc gcgcgagcca gacgcggttg
    19141 cgcgcgacca tgcggtggta gaccgcgtgc cgggagggcg cggtcgtggg gtggtacagc
    19201 accatgtcgg accggtagtc gatcatccag cccgcgtcga gggcccgcca tgccaggtcg
    19261 gtttcctcgt gcgcgtagaa gaattcgtcc gggaggccgc cgacttcggc gaggacctgg
    19321 gtgcgtacgg cgttggcgcc gccgaggaag gtggtgaccc gggaggagcg catcgggtcg
    19381 gaggcccgca gccggggcac atggcgccgc tgggtctcgc cggtgtcggg gtcggcgatg
    19441 cggaagctga cgatgccgag cttcgggtcg tcctcgaacg ccttgcggca cagttcggcg
    19501 gtgtcgtggt gcgcgagcag gccgtcgtcg tcgaggaaga ggaggacgtc gacgtcccgg
    19561 ccgctggggc cgaacgcctc tatgcctatg ttgcggccgc cggggatgcc gaggttctcg
    19621 gacagctcga ccgtccggac gccctcgggg acgtccggga cgggcgagcc gttgccgacg
    19681 acgaccacct cgacccggtc gccgtcctgc ttggcgaccg agtcgagaag ggcgcggagt
    19741 tcgtcggggc ggttgcccat ggtgatgatc accgcgccga ccttcatgcc gccgctcact
    19801 tcagcctgct ggaagcgagg atggacacca ggtgcagcag tgtctggagc agcgcgatgc
    19861 ccgcgagtac ggcgacgccg agccgcgaga agtacaggtc gcccctggcc tggtccacga
    19921 ccgcgagcac gaggatcagc agggaggcct cgacgccgag gatcagccgg tggaacttca
    19981 gggcggcggc ggccttgcgg gccagcgcca taccggaggt gcgcggctcg gaggccgact
    20041 cctgcaccgg cggcttcccg gtctggtgcc gggcgacacc gacgaggtcg gtctcggcct
    20101 tgatcaggat cgcgccgagg gcggcgagcg tgccgaggaa ggcccacagc cagtcgatcc
    20161 gcccggtgcc ccacaggtcg gcggcgcgca gcccgaagcc gacgagcacg gccgcgtcgc
    20221 acaggtaggc gccgacccgg tccacgtaga cgccggccat cgagaactgc ttgcgccagc
    20281 gggcgatctc gccgtcgacg cagtcgaaca gcagatacag ctggaccatc agcacaccga
    20341 ggacggcgcc cgtgatgccc ggcaccaaca gggcaggcgc ggcgaggacg ccgaagacgg
    20401 tcatcaggta ggtcagctgg ttgggcgtga cccgggtgtt caccaggtgc cggtcgatgc
    20461 gcagcgagat ttcgcgcatg tagagccggc cggcccagtg ctcgccgctc cgccggtcct
    20521 tcacacccgg ggggtgaacg accgggcgga gttcagctac tgatggcttt ggcatagtcg
    20581 gcgtatgcgt ccttgatctg ttcggtactc agttcgaggt gctcgaggat ggtgtagcgg
    20641 cccggcctgg tctgcggggc gaactccacg acctggacga actcgtccac ggtgaagccg
    20701 atttcgtccg ggaggacggg caggccgtgg tggcggagga cttcggccat cagacccgcc
    20761 atgtcgtggt tgccgcgcag gaacgtggcg aacgcgccgc cgaggccgca ctgttcgccg
    20821 tgcagggcgt tgcgccgggg gaagctcagg tcgaacgcgt ggctgatctc gtggcaggcg
    20881 cccgaggcgg gacggctgtc gccggccacg gacatggaga tcccgcacag gacgagggac
    20941 tcggacaggg tcgtcaggaa gtcgtcgtcg ccgacgccgc cggggtggcg cagcacggcc
    21001 tcggcggcct ggcgggccat ggcggcggcc agtccgtcga ccttctcgcc ggtctcccgg
    21061 ctggacagct cccagtcggc cacggcggag atcttgcaga tcacatcgcc gatgccggcc
    21121 cgcacgaagc gcaccggggc ttcacggatg acgtcgaggt cgatgacgat cccgatcggg
    21181 ttcggcacac cgtaggagcc gcggcccgcg tcgttgtcga gcgtcgcgac cggcgagcac
    21241 agaccgtcgt tggcgaggtt ggtggcgacg gcgaccagcg gcaggccgac ccgggcggcc
    21301 gcgtacttgg cgcagtcgat gaccttgccg ccgccgagcc cgaccacggc gtcgtagtga
    21361 ccgcccttct tgatcgagtc ggcgagccgt accgcaccgt cgatggtgcc gtcggcgtcg
    21421 cagaaccagt cggcctccgg cagcgccggg gcgaaccggt cgcgcagagc ggcgccggag
    21481 ccggggctga tcgcgaaggc catccggccc gacggcgcga tgcgctggtc cgacaggatc
    21541 gtcgccaggt catcgagcgc gccgggacgg atgtccacga cgatcggcga ggggatgagc
    21601 ctcgtcagta ctggcacgcg atctcacgtc ccttggcgag gtcgtcgtgg ttgtcgatct
    21661 cgacccagtt gacgtcgccg atgggggcca cgtcgatgcg gaagccgcgg ttcacgagct
    21721 cctggtagcc gtgctcgtag aactgctgcg ggtccgtctc gaagaccgtc ttcagggcgt
    21781 cggccagctc gtcggcggcc tcgccctcga tgagggtgac gccgatgtac tcaccggtcg
    21841 cctcggccgg gtccatcagc ttggtgatct tcgacatgcc gccctcgggg ccgacgacga
    21901 ccttcatctc ctcgtcggcg agggacttca ccgtgtcgag ggcgaggatg atcttcttgc
    21961 cgtcgccgcg ggcggcgagc agggtcttct cgacggagac cgggtgcacg gtgtcgccgt
    22021 tggcgaggat caccgagtgc ttgatggcgt cacgcccgca ccacagggag taggcgttgt
    22081 tccactcctc ggccttgtcg ttgtcgatga gggtgatctt gaccccgtac ttggcctcca
    22141 gcgcctcgcg gcgctcgtac acggcctcct tgcggtagcc gacgatgatc gcgacctcgc
    22201 tcaggccgat ctcggcgaag ttgccgaggg tgaggtcgag aacggtgagg ctctcctcgt
    22261 cgccttcggg gccgaccggc accagtgcct tgggcagggt gtcggtgtag gggcgaagac
    22321 gccgtccggc gccggccgcc agcacgaggc cgatcatgcg ggttctcctt catcgtgtac
    22381 ggcgggtgcg ccggttttat gggcggtcac ccagaagcgg atgctctcga gaagcaccag
    22441 cagcgccacg gccacggcga gagccgtgag cgcgaccttg aaatctgtgg gcgcgagcag
    22501 cgcggccagg acggtgacca gcagggtcct gccttcgtgt ccgccgatcg cccgcaccag
    22561 ccaccgaggc ggcgctccgg cgtcgccgcg gatgcggtac accgtgtcgt agtgatggta
    22621 ggcgaccgcg cccaccagcc cgaaagcaac tggaagggct ccgttcactt cggctttggc
    22681 tgcgagtacc aggacggtgc cgtattcggc ggcgcggaac agtgggggaa tcagccagtc
    22741 gagggcgccc ttgagggggc gcgcgacggc gtccgcggac accacgacgt agacggcggc
    22801 ggcgaagacg accgtccaac cgggtccgtc gaaccaggcc gtgagcacca cgacaacggc
    22861 accggcgagg gccaggagcc gcgcgacaac cgcgtatcgg ctcggcgcga tacgcgtgag
    22921 cgcctcggcc aagggcccgc tgtccgccag gtccgccagc gcccgcgccg cccggtcggt
    22981 ccgccgcgcc ttgcgcgtca gcgaccgcag cacacggccc gctgtggtgt aagtcgcagc
    23041 gaacgcgcac ccgatgagca gcgcgtagaa ggtgatacga ggagtggtga ccgccgtgag
    23101 gacggcgatc atcgcccagc gctcgccgat cggcaggacg atcatccgcc gcacccagac
    23161 cgtccagccg acgctgtcga gcttgccgga gagggccgcg gtggggctgg tgttggcggt
    23221 ggcgtcgtga ttcgcctcgt tgaaggagaa gtcgacgacg tggcggcaag tctgcaggac
    23281 catcgcgccg agggcgagcg cccatacatc gtcaccgccg cgcgcggctc ctagggcgag
    23341 gcccgcgtag taggcgtatt ccttggcgcg gtcgaaggtg gcgtcgagcc aggcgccgag
    23401 cgtcgagtac tgcagcgagt agcgggccag ctggccgtcg gtgcagtcga ggacgaagga
    23461 gaagatcagc agcagaccgg cggcgacgaa gccgcctcgg gtgccggtgg ccgcgcagcc
    23521 cgccgcgatc agggcggtga tcagcgaggc cgtggtgacc tggttcgggg tcaggcccct
    23581 gcgtgcgcac cagcgggcga ggtagcggga gtacgggctg acgcagtacg tggtgaagaa
    23641 gccgtcgcgg gacttcaccg ccgtacgcag ccgtacggcc tcgtcgtcga cgtcggcgac
    23701 cgcctggcgg gcctcgttgc gggcctgcgg gtcggcgggg acgacggcga ccagggtgcc
    23761 cagctcgggc cggtgcaggg tgacaccgtc ggcgtcgagg gcggcgatga cccggtcggc
    23821 gaggttgtcc acggcgaccg cggtggtgcc gctcgcggcg gagctctcgc gggccagcgc
    23881 ccggatcagc gccggacggg cggtggcccg cacggtcacg gcgcccggca ccgccgcggc
    23941 ctcgaagcgt gggtcggtga gcccgaggcg cagtgcgtgc gcatggccca cgaaccgggc
    24001 gtcgacgatc gcgacccgct gacctgcggg aaccgtcgcc aggagcgtct cggcgtcacc
    24061 ggcgccggag gcgacccgca cgtcgaagcc gagcgaccgc agatcgccct ccagcgacga
    24121 tccgggcacc ggctgaccgg tgaggatggc ggtcgacaga cgaactcact ccctgggtgc
    24181 cgacgcgacc gcgccggaca tgtacgtggt ttggggcgcc ccggccctgg ggcccggcgg
    24241 cgtgtcggca gaggttatcg gatgaagaga agcagacgtt caccgcccgt tcacggcccg
    24301 atcagttcga cctgctcaag ccgtcggccc tccgccgcga tcatcatcgg ggatttgagg
    24361 gttgtgccac aaactcctgt gtgggatatc ggttgatagg gggcaaaggg agggggccac
    24421 ccctcgacag gaggccgccg gccgcgcccc tcaaggggcc cggggaactg cgcgaccagc
    24481 cacgaacgaa gccgcacccg ccaaccctgc acacccccta cggcgaatgg gcacaacaag
    24541 caccccacat aaggttgacc gcatgacatg gctgatcaca ggcggggcgg gctacatcgg
    24601 cgcacacgtg gcgaaggtca tgaccggcgc cggcgagcag gtcgtgacac tcgacgacct
    24661 gtccgccggg gtcccgggcc gcctcccgaa gagcatcccc ctgatacacg gctccgccct
    24721 cgacggcgac ctcctcaagc gcgtactcgc cgagcacgcc gtgaccggcg tggtccacct
    24781 cgcggcccgc aagcaggtcg gcgaatccgt cgcccagccc acccgctact accaggagaa
    24841 cgtcggcgct ctcgccaccc ttctggaggc gtccgccgga gccggcgtgc ggcgtttcct
    24901 cttctcctcc tccgccgccg tctacggcaa cccggacgtg gacctcatca ccgaggacac
    24961 cccgtgcgcc ccgatgagcc cgtacggcga gaccaagctc gccggtgagt ggctggtccg
    25021 tgcggcgggc gaggcgcacg gcatcgcgac cacgtgtctg cgctacttca acgtggcggg
    25081 cgccgcggaa ccggcgctgg cggacaccgg cgtcttcaac gtcgtcccga tggtcttcga
    25141 ccggctcacg cgcgacgagg ccccgcggat cttcggggac gactacccga ccccggacgg
    25201 cacctgcgtc cgcgactaca tccatgtcgc cgacctggcc cacgcacacc tcgcggcggc
    25261 ccgccatctc accgccgaag ggggcgcggg cgatctcacc gtgaacatcg gccgcggcga
    25321 aggcgtttcg gtccgcgaac tcgtcaccct catcggcgag gtgaccggcg accgccggcc
    25381 cgcgctcgtc gaaccgcgcc gccccggcga cgcgccccgc gcggtcgcct cggccgcgct
    25441 ggccgagcgg gagctcggct ggacggcccg gcgcggggta cgcgagatgg tcgaatcggc
    25501 ctgggagggc tggcggctga accacggcct ctgaacggcc accgatcatg ggcaccgctc
    25561 tgacctgcat atcgtttccg caggtcaggg cacatgacaa cggtgttcag tgccgcgttg
    25621 cctggtaccc cccgcccgta gttcactgtg atcgcgagcc gaacacacga gcgcactgag
    25681 agggcggttt ccatgggggc tgggcacgat cacgggcacg cgcatcacgc gccgaccagt
    25741 ggtacggcgg cagcggcgta ccgcgggcgg ctgcggatcg cgctgtcgat cacgctcacc
    25801 gtcatggcgg tcgagctcgt cggcggtgtt ctcgccgatt cgctggcgct catcgcggac
    25861 gcggcgcaca tggcgacgga cgcggtgggc cttggcatgg cgctcctcgc gatccacttc
    25921 gccaaccgcc cggcgaccgg caaccgcacc ttcggtttcg cgcgcgccga gatactcgcg
    25981 gcgctcgcca actgtctgct gctgctcggt gtcggtggct atgtgctgta cgaggcgatc
    26041 cagcgcttca tcacgcccgt cggaacccag ggcgggctga ccgtcgtgtt cggtgcgatc
    26101 ggtctcgtcg cgaacatgat ctcgctgacg ttgctgatgc ggggccagaa ggagagcctg
    26161 aacgtacggg gagccttcct ggaggtggcc gcggacgcgc tcggctcgct ggcggtgatc
    26221 atctccgcga cggtcatcct gctcaccggc tggcaggccg cggacccgat cgcctcactc
    26281 gtcatcggcc tgatgatcgt cccgcgcacg gtgaagctgc tgcgcgagac cctcgacgtc
    26341 ctgctggagg cggcgccgaa gaacgtcgac atggccgagg tacgagccca catactggcg
    26401 ctgccgggtg tggaggacgt ccatgatctg catgcctgga ccatcacctc cgggatgccg
    26461 gtgctctccg cccatgtggt ggtcggctcc gacacgctgg actccatcgg ccacgagaag
    26521 atgctgcacg acctccaggg gtgcatcggc gatcacttcg acgtcgagca ctgcaccttc
    26581 cagctggagc cgggcggcca cgcggaacac gaggcgaagc tgtgtctgtg acgaccgact
    26641 ggacgacgcg accggagacc tccgcggacc gagagggggt gtacggcgt
//
