LOCUS       NZ_CP102509            21119 bp    DNA     linear   CON 06-JAN-2024
DEFINITION  Streptomyces sp. NBC_00162 chromosome, complete genome.
ACCESSION   NZ_CP102509
VERSION     NZ_CP102509.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. NBC_00162
  ORGANISM  Streptomyces sp. NBC_00162
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8635149)
  AUTHORS   Nielsen,J.B., Gren,T., Mohite,O.S., Joergensen,T.S., Klitgaard,A.,
            Mourched,A.-S., Blin,K., Larsen,T.O., Weber,T., Gotfredsen,C.H. and
            Charusanti,P.
  TITLE     Identification of the biosynthetic gene cluster for pyracrimycin A
            and elucidation of a key reaction during its biosynthesis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8635149)
  AUTHORS   Joergensen,T.S., Gren,T., Blin,K. and Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2022) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 05-AUG-2022
            Assembly Method :: Flye v. 2.9-b1768; Polypolish v. 0.5.0; POLCA
            polisher from MaSuRCA v. 4.0.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 40.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina Nextseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/05/2024 18:03:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,275
            CDSs (total)                      :: 8,175
            Genes (coding)                    :: 7,805
            CDSs (with protein)               :: 7,805
            Genes (RNA)                       :: 100
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 371
            CDSs (without protein)            :: 370
            Pseudo Genes (ambiguous residues) :: 0 of 371
            Pseudo Genes (frameshifted)       :: 186 of 371
            Pseudo Genes (incomplete)         :: 231 of 371
            Pseudo Genes (internal stop)      :: 27 of 371
            Pseudo Genes (multiple problems)  :: 68 of 371
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:41:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7373228
            Orig. end                         :: 7394347
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102509.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Tilmann Weber, Dr.
            Professor, Novo Nordisk Foundation Center for Biosustainability,
            Kemitorvet, 220, 327D 2800 Kgs. Lyngby, Denmark.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21119
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="31"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21119
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21119
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11119](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11119
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    53..66
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.24"
                     /tool="antismash"
     gene            complement(1236..1913)
                     /locus_tag="JIW86_RS34050"
                     /old_locus_tag="JIW86_34050"
     CDS             complement(1236..1913)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004934729.1"
                     /locus_tag="JIW86_RS34050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34050"
                     /product="HAD family phosphatase"
                     /protein_id="WP_257557790.1"
                     /sec_met_domain="HAD_2 (E-value: 7.2e-34, bitscore: 116.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISVIFDLDGTLVDSEPNYYESGRRTLERHGVPDFTWEQHSRFIG
                     IGTLETLEILRERYGIQAPVEQLLAEQNAAYLELARTGTEVFPEMRKFVERLRAEGVPM
                     AVASGSSREAIDAVLAGTGLDALLTTVVSAEEVAHGKPAPDVFLEAARRLGAEPADCVV
                     VEDAEPGALAARAAGMECVAIPYVAERAHDAAFADAGLLFPGGQREFTAEAAYDWLTAR
                     TAL"
     misc_feature    1947..1962
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.22"
                     /tool="antismash"
     gene            complement(1959..2438)
                     /locus_tag="JIW86_RS34055"
                     /old_locus_tag="JIW86_34055"
     CDS             complement(1959..2438)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003977712.1"
                     /locus_tag="JIW86_RS34055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34055"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_257557792.1"
                     /transl_table=11
                     /translation="MAVDELDTRILRLLIEQPRTSVREYARILGVARGTLQARLDRLER
                     TGVITGTGPSLSPAALGHPVLAFVHIEVTQGHLDDVGEALAAVPEIIEAFSITGGGDLL
                     TRVAARDNAHLEDVIQRLIQLPGVVRTRTEVALRERVAHRLLPLVEAVGRAARKA"
     misc_feature    complement(2474..2489)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.89"
                     /tool="antismash"
     gene            2587..4149
                     /locus_tag="JIW86_RS34060"
                     /old_locus_tag="JIW86_34060"
     CDS             2587..4149
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007500170.1"
                     /locus_tag="JIW86_RS34060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34060"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_257559541.1"
                     /transl_table=11
                     /translation="MNCLVTGATGYIGGRLVPELLAAGHRVRCLARSPEKLRDHPWAGQ
                     AEIVRGDATDPQSVAEALDGIEVAYYLVHALGGGSGFEERDRAAARIFAEQAHSAGVRR
                     IVYLGGLTPAGIPVRELSPHLRSRAEVGEILLAGPVPATVLRAAVIIGSGSASFEMLRY
                     LTERLPVMVTPSWVGTRCQPIAVRDVLRYLVGSATMAPEVNQAFDIGGPDVVTYEEMMR
                     RYAAVAELPHRLILRVPMLTPGLSSHWIGLVTPVPRALARPLAESLRHEVVCAEHDIAR
                     HVPDPPGAPVGFDQALSLALRRVREAEVTTRWSSASVPGAPSDPLPTDPDWAGGSLYTD
                     RREMAVEASPGALWRVVEGIGGENGWYSFPLAWSVRGWLDRLVGGVGIRRGRRDATRLR
                     VGDALDFWRVEEIEPGRLLRLRAEMRLPGLAWLEMYADPCPEPGRARYRQRALFHPHGL
                     LGHVYWWSVSPFHAVVFGGMARNIARAAERPAASDAPASAAAPAAGVPHDNRPAQPDPE
                     RDP"
     gene            4146..5519
                     /locus_tag="JIW86_RS34065"
                     /old_locus_tag="JIW86_34065"
     CDS             4146..5519
                     /EC_number="4.1.99.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944622.1"
                     /locus_tag="JIW86_RS34065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34065"
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="WP_257557793.1"
                     /transl_table=11
                     /translation="MNVAVVLYTSDLRLHDHPPLRAALASCDRVVPLFVRDHALAAAGF
                     APPNRQAFLADCLADLDAGLRERGGRLVIRSGDAVREVCALARETDADEVHMAAGVSGY
                     AHAREDRLRTALEAEGRRLHVHDMVITAVAPGAVLPAGSDHFAVFTPYFRRWAELPPRA
                     VAAAPRTVRLPEGLGSEPLPVRGALTGVSPGLARGGETEARRLLANWLRSGISRYEDTH
                     DDLAGDATSRLSPHLHFGTLSAAEAVHRSRAVGGPGAEAFVRQLCWRDFHHQVLAARPE
                     AAAEDYRPRHDRWRTGPAAEEETEAWKEGRTGYPVVDAAMRQLRQEGWMPGRGRLLAAS
                     FLTKTLYVDWRTGARHFLDLLVDGDLANNQLNWQWAAGTGTDTRPNRVLNPVRQGLRYD
                     PQGRYVHRWVPELAGLLAPHVHEPWRLPGLERARYDYPDPVVGLAEGLDRFRRARGTG"
     gene            complement(5557..6291)
                     /locus_tag="JIW86_RS34070"
                     /old_locus_tag="JIW86_34070"
     CDS             complement(5557..6291)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018604.4"
                     /locus_tag="JIW86_RS34070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34070"
                     /product="YoaK family protein"
                     /protein_id="WP_257557796.1"
                     /transl_table=11
                     /translation="MGVSLSGLMKVGAHPLRPSLTGLLIVLTAVTGLIEAVSLLALGPV
                     FTAMQTGNVLFLAFGLAREGNLPAVSSAVSLVAFAAGAVCGARMESAAEARGWRWVGLG
                     LYVEAALILAGAAVGWDVAPRYGHPAAAHVTVTVLLATAMGIRTVTSMRVNVPGVPTTL
                     VTRSMTSLIGSSALGHDSAFGYGTGAWRLRAKAVLSMFAGGLTGALLIRAGWTVGELLL
                     PAAAVVSAVALAHRTLPRLHTR"
     gene            6340..6933
                     /locus_tag="JIW86_RS34075"
                     /old_locus_tag="JIW86_34075"
     CDS             6340..6933
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996410.1"
                     /locus_tag="JIW86_RS34075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34075"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_215146916.1"
                     /transl_table=11
                     /translation="MSDLLLVRHGETAWSANGRHTGLTDLPLTARGVEEAISLAPYFRD
                     RHPAMVLTSPLRRAVATAQLAGLTGGVTDPDLHEWDYGGYEGVTTAEIKRTTPDWSLWT
                     DGVPPGDEAHPGENAAQVGARADRALARVAPVLRADGGNVVIVAHGHFLRVLTARYLGL
                     GPEQGRLFLLRTGTVSMLSTEHGLPVIAGWNTRP"
     gene            6981..8492
                     /locus_tag="JIW86_RS34080"
                     /old_locus_tag="JIW86_34080"
     CDS             6981..8492
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740155.1"
                     /locus_tag="JIW86_RS34080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34080"
                     /product="APC family permease"
                     /protein_id="WP_257557798.1"
                     /transl_table=11
                     /translation="MAEDSTGRDGPQVAVPEPGLKANAIGFLDALVIGLNSTSPAYSLA
                     AVLGPIVALVGIYAPGVMLASFVPMLLIAAAFYYLNKVDQDCGTTFSWVTRAMGPWAGW
                     LGGWAIAMTGVLVIGSLADVAVTFGLLAFGLDDWAANDVIRQALTVAVILAMTAICVIG
                     TELSAHLQDILILAQVFFLLTFAVVAIYRTYTGTSTLEEIEPSLSWLNPFGAGGAALTG
                     GLLLGVFMYWGWESAVNLTEEVENSATAPGKAGLWSTVVLLVTYVSVGFAVVGYAGTTF
                     LAENAAEEEAIFAVLAHEVMGGWDWVVLLAVCTSALASTQTTIIPASRTALSMARRHAL
                     PPPLSHIHPRFRTPDVSTWWVAGIAIGWYLVVNQISENALLDSLTALSLLIAFYYALTG
                     LACAVYYRRHLLESLHNLLFIGVGPVVGAALLLWLLVESVGDMSNPENSATGASWFGLG
                     PPLVIGIAIAVAGVLFMGYWRLRDGTFWQERRGVVDPDLVHGRKS"
     gene            8502..8930
                     /locus_tag="JIW86_RS34085"
                     /old_locus_tag="JIW86_34085"
     CDS             8502..8930
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740156.1"
                     /locus_tag="JIW86_RS34085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34085"
                     /product="universal stress protein"
                     /protein_id="WP_215146918.1"
                     /transl_table=11
                     /translation="MSVVLGYDESPGAERALRVALEVATAFGEPLVLVYGAAAPGPTGE
                     EYRAHREAVRQTGRSALARAVEAADEAGVPSAVEVVDDKPAQALLDAARRHDARVIIVG
                     TWGDSPIRGALLGSTPHKLLHLSPIPVLCVPTEHGETL"
     gene            9071..9997
                     /locus_tag="JIW86_RS34090"
                     /old_locus_tag="JIW86_34090"
     CDS             9071..9997
                     /NRPS_PKS="Domain: oMT (94-191). E-value: 5.9e-10. Score:
                     29.7. Matches aSDomain: nrpspksdomains_JIW86_RS34090_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008744116.1"
                     /locus_tag="JIW86_RS34090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34090"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_257557801.1"
                     /transl_table=11
                     /translation="MTGEPMDSNLAIQPPTGGQAFDEGQVRLYYSRKTADILHKYGPGP
                     RVHFHVGLFAPGATPNTTVSQRVLKCRIVESQEAIVEHAARTWGAYATPPGRLLDIGCG
                     IGGGSLYWAQEHGTKVTGLTVAADHVPVIEDFARQAGVSDRVTPLLADIHTFSTRKKYD
                     AAYAIESSGYMDRERLFEVVAKSLKPGGWFGIQEHFICRPEWTEFIDGYYKTRLGTLTE
                     YITAAEAAGFELEQDEDVTDRVAEFWVQSMAWNTAELDRVERCGAPSAWSRERLQESTI
                     THGKLFRIWRDHALETRLLLFRLGGGN"
     aSDomain        9353..9643
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JIW86_RS34090_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="5.90E-10"
                     /label="JIW86_RS34090_oMT.1"
                     /locus_tag="JIW86_RS34090"
                     /protein_end="191"
                     /protein_start="94"
                     /score="29.7"
                     /tool="antismash"
                     /translation="PGRLLDIGCGIGGGSLYWAQEHGTKVTGLTVAADHVPVIEDFARQ
                     AGVSDRVTPLLADIHTFSTRKKYDAAYAIESSGYMDRERLFEVVAKSLKPGG"
     gene            10001..11119
                     /locus_tag="JIW86_RS34095"
                     /old_locus_tag="JIW86_34095"
     CDS             10001..11119
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008744115.1"
                     /locus_tag="JIW86_RS34095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34095"
                     /product="hypothetical protein"
                     /protein_id="WP_257557809.1"
                     /sec_met_domain="T1TS (E-value: 2.2e-66, bitscore: 223.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPVYREDARPSRIGWQLPPFYWPFERDLIHPKAAELEERAIAWI
                     DAFGFYPDATERAWGLATRSVDFTCRIIPYGDVEPMLLFAEWNYWAFATDDWQDSDAGA
                     ARTASVVDQGTRLIRTLEAPGSGLLPPGPHTAALEDLVARTRAMLTPFQLRRFTEGVRD
                     WVFGAASQAANAERGVMPSLNDFAATRISVGGTRFLLTWCDVANGIDVPAEVLYSAPVQ
                     ALTDAAGFIVACDNDLFSYNKDDHHEPLEQNLLNVLARDYGCTPAEALPAAYALRDRAV
                     TLFVRLSEQLARDADDHLGRYLVSVEHWIAGDTEYHNRAPRYASPRNRNVLPVEGASYG
                     ITWSDTPSDPSIEPLPIPALAWWWQQLDDASR"
     gene            complement(11122..12495)
                     /locus_tag="JIW86_RS34100"
                     /old_locus_tag="JIW86_34100"
     CDS             complement(11122..12495)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019886332.1"
                     /locus_tag="JIW86_RS34100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34100"
                     /product="cytochrome P450"
                     /protein_id="WP_257557810.1"
                     /transl_table=11
                     /translation="MTTPPSPASPTPPPGCPAHRLYGPEAEADPMGLYEKLRAEHGAVA
                     PVLVQGDLPAWLVLGHRENLDVARTPSRFSRDPRGWRDQQEGRVPADHPLTPMTAWQPV
                     CHLVDGAEHERLRGAVTESLERFDRRGIRRYVKRFADQLIDQFAESGRGDLVADFAEPL
                     PMLVMTQLVGAPDSYGPRLVEAARDMLQGTETAVASFEYVSDILRELVMRKRAVPNRDF
                     TTWMTEHPTSLSDDEIVEHLRLVMIAAFETTANLIANTLRMVLTDGRFRANLSGGHMTL
                     PDALEQVLWDEPPFMTILGRWATGDTELGGAQIKAGDMLLLGLGAGNVDPDIRPDLTVP
                     VHGNRSHLAFSSGPHECPGQDIGRAIADTGIDNLLTRLPDLELAVPEDELQWTSSLMSR
                     HLVALPVRFTPRGSTVTGSTPVPRSAARTPRTPPPVVPVPGERPTGRGSWWARLLGRR"
     gene            complement(12492..13115)
                     /locus_tag="JIW86_RS34105"
                     /old_locus_tag="JIW86_34105"
     CDS             complement(12492..13115)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008744113.1"
                     /locus_tag="JIW86_RS34105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34105"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_257557812.1"
                     /transl_table=11
                     /translation="MDFESSEASPAGPRREDVLPATAAAAVKVVIVGGFGVGKTTLVGA
                     VSEIRPLTTEETMTQAGVGVDDTAGVERKTSTTVAMDFGRISINEELVLYLFGTPGQQR
                     FWFLWRGLFEGALGAVVLVDTRRLEVSFDVIGRLEERGVPFVVAVNSFPDAPQHPVEEL
                     RSALDLPASVPLVLCDARRRDSSRDVLMTLMRHLHSLAVTPEIS"
     gene            complement(13096..13455)
                     /locus_tag="JIW86_RS34110"
                     /old_locus_tag="JIW86_34110"
     CDS             complement(13096..13455)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018846603.1"
                     /locus_tag="JIW86_RS34110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34110"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_257557818.1"
                     /transl_table=11
                     /translation="MKEPGNNWEDGSPERLYVITGGRSGPLVPSGLDLVTLIVAKSGPR
                     PGMQPEHASIMRLCQAPLSVAEISAYLGLPVSVVTVLIDDLLTAGQVLSRAPVARAQLP
                     DLALIEAVIDGLRKL"
     misc_feature    complement(13375..13377)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13452..13859)
                     /locus_tag="JIW86_RS34115"
                     /old_locus_tag="JIW86_34115"
     CDS             complement(13452..13859)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008744111.1"
                     /locus_tag="JIW86_RS34115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34115"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_215146923.1"
                     /transl_table=11
                     /translation="MSQYQTNMDWMLKDLAESVPQTRHVIVLSADGLRMAQYGAETDTA
                     DRLAAACAGLQSLAGAVASELPGSNGRMRLVVIEMDGGFFYLMAAGAGAYLAVLAGEGV
                     DAGLMGQRMRDLVARIGEHLSSPPRSDRQTA"
     gene            complement(13856..15388)
                     /locus_tag="JIW86_RS34120"
                     /old_locus_tag="JIW86_34120"
     CDS             complement(13856..15388)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019886326.1"
                     /locus_tag="JIW86_RS34120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34120"
                     /product="ATP-binding protein"
                     /protein_id="WP_257557821.1"
                     /transl_table=11
                     /translation="MVREGSSPGSPGPTSPVVWALPALLTAALAAVTVALVAAPARTPV
                     AWVGAAAFVAVALSCGEAARRGKAVAALRATVAAQEAALFRQQTETVRLAEALLPDVVG
                     RLRKGEFPEDVLASLEDASTYQPGLTPAFRAAHHAVLRSVLDAVVAEEDLRDSAQRAFV
                     NIARRVQAIVHQQAQELREMEDRHGQSPAVFGDLLRLDHGTALIGRLADSIAVLGGARP
                     GRQWNKAVPLYSVLRGAMSRIIDYQRVELHSVSQVAVVGPAVEPLIHALAELLDNATRY
                     SPPQTKVHLTAVDVNSGIAIEIEDGGLSMSEEARNRAERMLRQAQEGIDLTDLGETPRL
                     GLAVVGRLSQAYDFRVSLRSSAYGGVRAVLVVPQGLITTVSTATGVAHGIGTASGPRAA
                     LEPAAAPPQPPRPATGPQVPAFVEEVPLVTERTPNGLPQRRRKARATASDGPAAVAQTT
                     AEDPDRTEAQPGMWLAAFQSGLSGDSRTAGSHIADSQTTDASPASASKGEQP"
     gene            complement(15693..16892)
                     /locus_tag="JIW86_RS34125"
                     /old_locus_tag="JIW86_34125"
     CDS             complement(15693..16892)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237354.1"
                     /locus_tag="JIW86_RS34125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34125"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_257557823.1"
                     /transl_table=11
                     /translation="MVSERDGLEARLRAMEEALERIGTSGNERGTCRELTGFLFRTLCD
                     AAAVDLTGRGTVSDRVAEAGATDLLRDPSPDAPAAVRALDHGHSVRTWSGRAGDRPLYL
                     VSVPLIGPGGGEAYGRLLVVRSGEDFSDHETATLHFAARLASVHIGHARRLAATEKTAL
                     DLQRALVSEPGRPHPNLDIASRYLPVGLRALVGGDWFETVRLHFGRTLLVVGDVMGHGL
                     DAAVDMNAYRSVLREVASTELAPHRVLRRLDTLSASDEGRRPATCLLVRIDPARGMAVY
                     ASAGHLPPAVFSGDGTGELLEVPVGPPLGTGIGGYEALARPITADQTLLLYTDGLVERR
                     GEDIDTSLDRLAGLRMTPGARVEDIVTAVCDGLDAQHAEDDVAVLAARLRPRPSPHAGT
                     "
     misc_feature    16950..16965
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.27"
                     /tool="antismash"
     misc_feature    complement(16956..16969)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.36"
                     /tool="antismash"
     gene            17017..19005
                     /locus_tag="JIW86_RS34130"
                     /old_locus_tag="JIW86_34130"
     CDS             17017..19005
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019334.4"
                     /locus_tag="JIW86_RS34130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34130"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_257557824.1"
                     /sec_met_domain="Pkinase (E-value: 1.9e-51, bitscore:
                     173.7, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGAGARLVGGRYRLIELVGQGGMGRVWRGHDTTLDRQVAVKEVL
                     LPEGIAPGEREELLRRTLREAQVAAQLNHPGIITVHDVVEHTGAPWIVMEFVAGRSLGA
                     LVEQDGRLPWERVAAIGAEMADALAQAHAAGVVHRDLKPDNVLLQGRRTIITDFGIARV
                     LDGSGATRLTRTGIIVGTPQYMPPEQLEGGDAGAPGDMWSLGATLYAAVEGAAPFAAPS
                     LMSLFHAIMTKPLPPARHAGRLAPVLEELLAKDPGKRPTAAALAERLAAVPHPRTQPDQ
                     RPAEPRQLHHLSTVTAPAPRANAVHPPTRHEAPPARPSPAAAPRPAPAPPASRTPRRRT
                     VLFAGAAAVAGATGAVWAWKAGSSDTSDRPGIATLHGHTYMINSLAFSPDGKTLASASD
                     DSTVRLWDVQARAHLGTLTGHTDMVFSVAFHPDGKTIATASADKTVRLWDTASRKAVAT
                     LGSHTARARAVAFDPTGKTLASGGQDNTVLLWNVTARTRISTLAVPGEAVHTVSFSPDG
                     KTLAASAGWGPAARRWDMRSMKSTDIAENGGTTKSISFSPDGKTLAVSEPYRTASLWDV
                     ASGTLTGTLATVHTDFVNMVAFSPDGRTLATASDDKTVRLWDTATQRKAATITGHGDQV
                     ISLAFSPDGALLATGSRDKTVRLWALT"
     misc_feature    17064..17078
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(19280..19294)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.98"
                     /tool="antismash"
     gene            19288..20784
                     /locus_tag="JIW86_RS34135"
                     /old_locus_tag="JIW86_34135"
     CDS             19288..20784
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262596.1"
                     /locus_tag="JIW86_RS34135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_34135"
                     /product="FUSC family protein"
                     /protein_id="WP_257559542.1"
                     /transl_table=11
                     /translation="MFVAPDPGRMRLRNSARAVIGVGAAVALAELCGLSLTASITGGLA
                     ALLALFTVVDSSVRAQRATTALLPLAGFPVLALATTLHGVPLARDAAFLAVVFAGVYAR
                     RWGPRGHALGIFGFMMFFVTQFLHAVPGQLPELYAAVGLALLAAGAVRFALWPIERRTP
                     PAAAPPGLPGAGLARPTTRQAFQATAACAFALAIGQALSEDRWYWAVGTAWWIFVNTAS
                     RGETLVRGFRRVLGTVLGIAAGLLIAVPLHGAPAPTAALVAVCVFGIFYTAAPSYSWMM
                     FFVTVMAGLLYGLLGVLHPGLLLLRFQETAIGAFGAALAVVIILPVTTHGANDAWIQRA
                     LECVRASTAAALDRLAGDPAADPAPHAAELELLLGRVRMALAPLVHPLSPLRARKARAR
                     QVLALLDDCAREVRGLVAVAADPQASHDARLAAACWRVEAAVQALTARDSTPELTAPPK
                     PRPVAPAEPALAHLHGLEHALVALAVPLRTDPRAPLVISA"
ORIGIN
        1 ggatgcgggg cgtccgcgtc ccaccgctcg ggccggaagg cctccggatc cgggaaccag
       61 cgttcgtccc ggtgcatcga ccacgggctg gtccacagcg cggtccccgc gggtacgggg
      121 cgcccgccga tgctcgcgcc ctccccggcc accgccgaga tcagccagat cggcgggtag
      181 atccgcagcg actccttgac cacctgccgg gtccagggca gccgcgcgta gtcgtcgtac
      241 gtcggcagcc gcccgccgag cacccggtcc agctccccgg tcagccgggc ccgcgccccg
      301 ggcgcccccg acaggagttg ccaggcccag gtcagggtgg tcgaggtggt ctcgtggccg
      361 ccgatgtaga gggtgatcga ctcgtcccgc agctccttgc gggacagcgg ggcgccgtgt
      421 tcgtcgcggg ccgcgagcag ccggctcagc aggtcgtccc gctcggcccc ggcggccgag
      481 gccgcctcgt gctcccgtat gacgtgtgcg atctcccggt ccaggaccgc cacggcctcc
      541 cgcatccgcc gtcgcccggg cgtccgcacc cacggcggca gaaacagcgt cagcccccgg
      601 aactcggccc ccagttcccg ctgggcggtg gccatggccg cgctgatggg cgcctcccgg
      661 ccggcggcgt cgctcccgaa cagcgtgcgc accgcgatcc gctgggtgag tccggccatc
      721 tcccggtgca cgtcgatccg gtcgccctcg cgccagctcc cggccagcgc gtccgcgcac
      781 tccaccatcg tggcggcgta cgagcgcact tggcgcggcc ggaccgcggg ctggaccagg
      841 gcccgcttgc gccgccattc gtccccggtg gccacgacga ccccgtcgcc cagcaactgg
      901 tggaaggccc agcccagttc catcggcttg aaggtgccct ccacggcccc gagcagctca
      961 ccggcgtgct cgggccgcga gatcagcacg ttgcgctgcg gcccgagcgc ccacggcacc
     1021 cagtccccgt agtcatcgcg cagcgactcg aagaaggcca acgggtcgcg ggcgaaggcg
     1081 ggcagattcc ctatcagggg ccactggcgc ggcccgctcc cggcgccccg gggcagcgtg
     1141 gtggcggtca cgcaggcatc ctggcagccg ccgcgcgagg gcaccagagg accgccaggc
     1201 ccgtcggtga acggcccccg ccgccccgga cggcgtcaga gcgcggtgcg cgcggtcagc
     1261 cagtcgtagg ccgcttcggc ggtgaactcc cgctgtccgc ccgggaagag cagcccggcg
     1321 tccgcgaagg cggcgtcgtg tgcgcgctcc gccacgtacg ggatcgccac gcattccatg
     1381 ccggccgcgc gggccgccag cgctcccggc tccgcgtcct cgacgaccac gcagtcggcg
     1441 ggctcggcgc ccagccggcg ggccgcctcc aggaacacgt ccggggcggg cttgccgtgc
     1501 gcgacctcct cggcggagac caccgtcgtc agcagggcgt ccagaccggt accggccagc
     1561 accgcgtcga tcgcctcgcg cgaggaaccg gaggccaccg ccatcggcac cccctcggcg
     1621 cgcagccgct ccacgaactt ccgcatctcc gggaagactt ccgtccccgt ccgggccaac
     1681 tcgaggtagg cggcgttctg ttcggcgagc agctgctcca ccggcgcctg gatcccgtac
     1741 cgttcccgga ggatctccag cgtctccagg gtgccgatgc cgatgaagcg ggagtgttgc
     1801 tcccaggtga agtccgggac cccgtgccgc tccagagtgc ggcgccccga ctcgtagtag
     1861 ttcggctcgc tgtccacgag ggtgccgtcg agatcgaata tgacggaaat catccgttgt
     1921 gcccgtcctg ccggtcgtgt cctgtcttta ccatcctgtc aggctttgcg agcagcccgt
     1981 cccacggcct cgaccagcgg cagcaaccgg tgcgcgaccc gctcgcgcag ggccacctcg
     2041 gtgcgggtgc ggaccacccc cggcagctgg atcagccgct ggatcacgtc ctccagatgt
     2101 gcgttgtcgc gcgccgccac gcgcgtcagc aggtccccgc caccggtgat cgagaaggcc
     2161 tcgatgatct cgggaacggc cgccagcgcc tcgcccacgt cgtccaggtg cccctgggtc
     2221 acctcgatgt gcacgaaggc cagcaccgga tgccccagcg cggcggggga gagcgagggc
     2281 cccgtcccgg tgatcacccc ggtgcgctcc agccggtcca gccgtgcctg cagcgtgccg
     2341 cgggcgacgc cgaggatgcg ggcgtactcg cggacactgg tgcgcggctg ctcgatcagc
     2401 aggcgcagga tcctcgtgtc gagctcgtcc accgccatgc ccagactgta ccaatggccc
     2461 agttcaccgg atcttgacca ggcggtgatc cgcggggacg ccgcatggca ctcccggaag
     2521 cgaggggtga gtgtgttgtg ggcggcattc gcaccggatc cacgagcgga gagagccatg
     2581 acaggtatga actgcctggt caccggggcc accggctaca tcggcggccg actggtgccc
     2641 gagctcctcg ccgccggaca ccgcgtccgc tgcctggccc ggtccccgga gaaactccgt
     2701 gaccatccct gggccggaca ggccgagatc gtccgcggcg acgccaccga cccgcagtcc
     2761 gtggccgagg ccctggacgg catcgaggtg gcctactacc tcgtgcacgc cctcggcggc
     2821 ggctccggat tcgaggagcg cgaccgcgcc gccgcccgca tcttcgccga gcaggcgcac
     2881 tccgccggag tccgccgcat cgtctacctc ggcgggctca cccccgccgg catccccgtc
     2941 cgcgaactct ccccgcacct tcgctcccgc gcggaggtcg gcgagatcct cctggccggc
     3001 cccgtgccgg ccaccgtcct gcgcgccgcc gtcatcatcg gatccggttc ggcctccttc
     3061 gaaatgctgc gctacctcac cgagcggctg cccgtcatgg tgacgcccag ctgggtgggc
     3121 acccgttgcc agcccatcgc cgtccgcgac gtcctgcgct acctcgtcgg cagcgccacc
     3181 atggcgcccg aggtgaacca ggcgttcgac atcggcggcc cggacgtggt cacgtacgag
     3241 gagatgatgc gccgctacgc agccgtggcc gagctgcccc accggctcat cctgcgcgtc
     3301 ccgatgctca cccccggcct gtccagccac tggatcggcc tggtcacccc cgtaccgcgg
     3361 gcgctggccc ggccgctcgc cgaatcactg cgccacgagg tggtctgcgc ggagcacgac
     3421 atcgcgcgcc acgtccccga cccgcccggt gcgccggtcg gcttcgacca ggccctgtcg
     3481 ctggccctgc ggcgggtgcg ggaggccgag gtgaccactc gctggtcctc cgcctccgtg
     3541 ccgggcgcgc ccagcgaccc gctgcccacg gaccccgact gggcgggcgg cagcctctac
     3601 accgaccggc gggagatggc cgtcgaggcc tcgcccggcg cgctgtggcg ggtggtggag
     3661 ggcatcggag gcgagaacgg ctggtactcc ttcccgctgg cctggtccgt acgaggctgg
     3721 ctcgaccggc tcgtaggcgg agtcggcatc cgccgcggcc gccgcgacgc gacccggctc
     3781 cgggtgggtg acgccctgga tttctggcgg gtggaggaga tcgaaccggg ccggctgctg
     3841 cgcctgcgcg ccgagatgcg gctgccgggc ctggcctggc tggagatgta cgcggatccc
     3901 tgccccgagc ccggccgcgc gcgctaccgg cagcgggcgc tgttccaccc gcacggactg
     3961 ctcggccacg tgtactggtg gagcgtgtcc cccttccacg ccgtggtgtt cggcgggatg
     4021 gcccgcaaca tcgcccgcgc cgccgaacgt ccggccgctt ccgatgcccc cgcatccgcc
     4081 gcggcccccg cggccggagt accgcacgac aaccgtcctg cccagcccga cccggagcga
     4141 gatccatgaa cgtcgcggtg gtcctgtaca cctccgacct gcgcctgcac gaccatccgc
     4201 cgctgcgcgc ggccctggcc tcctgtgacc gggtggtgcc gctcttcgtc cgcgaccacg
     4261 ccctcgcggc agccggattc gccccgccca accggcaggc cttcctcgcc gactgcctcg
     4321 ccgacctgga cgccggactg cgcgagcgcg ggggccgcct cgtgatccgc tccggggacg
     4381 ccgtccggga agtctgcgcc ctcgcgcggg agacggacgc cgacgaggtc cacatggccg
     4441 cgggggtcag cggctacgcc cacgcccgcg aggatcggct gcgcaccgcc ctcgaagcag
     4501 agggccgccg gctgcacgtg cacgacatgg tgatcaccgc ggtcgccccc ggggccgtcc
     4561 tgcccgccgg ctccgaccac ttcgccgtct tcacgcccta tttccgccgc tgggccgagc
     4621 tgccgccgcg ggccgtcgcc gcggcccccc gcaccgtccg gctccccgaa ggcctcggct
     4681 ccgagccgct gcccgtgcgc ggcgccctca ccggagtctc cccgggcctc gcccggggcg
     4741 gcgagacgga ggcccgccgg ctgctggcga actggctgcg ctccggcatc tcccgctacg
     4801 aggacaccca cgacgacctg gccggcgacg ccacctcccg gctctccccg cacctgcact
     4861 tcggcaccct ctcggccgcc gaggccgtcc accggtcccg ggccgtcggc ggcccgggcg
     4921 ccgaggcctt cgtccggcag ctgtgctggc gcgacttcca ccaccaggtc ctcgccgcac
     4981 gccccgaggc ggccgccgag gactaccgcc cccgccacga ccggtggcgc accggcccag
     5041 ccgccgagga ggagaccgag gcctggaagg agggccgcac cggctacccg gtggtggacg
     5101 ccgcaatgcg ccagctgcgc caagagggct ggatgccggg ccgcggccgg ctgctcgccg
     5161 cgagcttcct caccaagacc ctgtacgtcg actggcggac cggggcccgc cactttctgg
     5221 acctcctggt cgacggggac ctcgccaaca accagctcaa ctggcaatgg gccgcgggca
     5281 cgggcaccga cacccgcccc aaccgcgtgc tcaaccccgt ccggcagggc cttcggtacg
     5341 acccgcaggg ccgctacgtc caccgctggg tgccggagct cgccgggctc ctcgcgcctc
     5401 acgtgcacga gccgtggcgg ctgccgggcc tcgagcgggc gcggtacgac tacccggacc
     5461 cggtggtggg gctcgccgag ggactcgacc gcttccggcg ggcgcggggg accgggtgag
     5521 cgccgtgcgc cgccgacgcc ccggtgacga cgcgcactag cgggtgtgca gccggggcag
     5581 cgtccggtgc gcgagggcca ccgccgacac cacggccgca gcgggcagca gcagctcgcc
     5641 cacggtccac ccggcccgga tcagcagggc cccggtcagc ccgcccgcga acatcgacag
     5701 caccgccttg gcccgaagcc gccaggctcc cgtcccgtac ccgaaggcgc tgtcgtgtcc
     5761 cagggccgag ctgccgatca gcgaggtcat ggaccgggtg accagggtcg tcggcacgcc
     5821 gggcacgttc acccgcatgc tcgtcaccgt gcggatgccc atcgccgtcg ccagcagcac
     5881 ggtcaccgtc acatgcgcgg cggccggatg cccgtaccgc ggcgccacgt cccatccgac
     5941 ggccgcaccg gccaggatca gcgcggcctc gacgtacagg ccgagcccga cccagcgcca
     6001 cccccgggcc tccgcagccg actccatccg cgccccgcac acggccccgg cggcgaacgc
     6061 caccagcgac accgcggacg acaccgcggg cagattgccc tcccgcgcga gcccgaacgc
     6121 caggaagagc acattgcccg tctgcatcgc ggtgaagacc ggcccgaggg cgagcaggct
     6181 caccgcctcg atcagcccgg tgaccgcggt caggacgatc agcagccccg tcagggacgg
     6241 acgcaacggg tgcgcaccca ccttcatgag gcccgacagt gacacgccca cccccgaccc
     6301 tcggcgccga catgccggac agggcctagg gtccggagga tgagcgacct gctgctggtg
     6361 aggcacggcg agacggcgtg gagcgcgaac ggacggcaca ccgggctcac cgacctcccg
     6421 ctgacggcgc gaggggtcga ggaggccatc tcgctggccc cctacttccg cgaccgccac
     6481 ccggcgatgg tgctgaccag cccgctgcgc cgggccgtcg ccacggcgca gctcgcgggg
     6541 ctcaccggcg gggtcaccga ccccgacctg cacgagtggg actacggggg ctacgagggc
     6601 gtgaccaccg cggagatcaa gcggaccacc cccgactggt ccctgtggac cgacggggtg
     6661 ccgcccggcg acgaggccca ccccggcgag aacgccgccc aggtgggcgc ccgcgcggac
     6721 cgcgccctgg cccgggtcgc cccggtgctc cgcgcggacg gcggcaacgt ggtcatcgtc
     6781 gcccacggcc acttcctgcg cgtcctcacc gcccgctacc tgggcctggg ccccgagcag
     6841 ggccggctgt tcctgctgcg caccggcacg gtcagcatgc tctccacgga gcacgggctc
     6901 cccgtgatcg cgggctggaa cacccgcccg tagaggtctc ccgcctcgcg cggcggccgc
     6961 cctcgggcga cgatgcctac atggccgaag acagcacggg ccgcgacgga ccgcaggtcg
     7021 ccgtcccgga gccgggactg aaggccaacg cgatcggatt cctcgacgcg ctggtcatcg
     7081 gcctgaactc cacctccccc gcctactcgc tggccgccgt gctcgggccg atcgtggccc
     7141 tcgtcgggat ctacgcgccg ggcgtgatgc tggcctcctt cgtcccgatg ctgctgatcg
     7201 ccgccgcctt ctactacctc aacaaggtcg accaggactg cgggacgacc ttctcgtggg
     7261 tcacccgggc catgggcccc tgggcgggct ggctcggagg ctgggccatc gccatgacgg
     7321 gcgtactggt catcggctcc ctggcggacg tggccgtcac cttcggcctg ctcgccttcg
     7381 gactcgacga ctgggccgcc aacgacgtga tccgccaggc cctcaccgtc gcggtgatcc
     7441 tggccatgac cgcgatctgt gtcatcggca ccgagctttc ggcccacctc caggacatcc
     7501 tcatcctcgc ccaggtcttc ttcctcctga ccttcgcggt ggtcgccatc taccgcacct
     7561 acaccggcac cagcaccctc gaggagatcg agccgtccct cagctggctc aacccgttcg
     7621 gcgccggtgg cgccgccctc accgggggac tgctgctcgg cgtgttcatg tactggggct
     7681 gggagtccgc ggtcaatctc accgaggagg tcgagaactc ggccacggcg ccgggcaagg
     7741 ccggactgtg gtcgacggtg gtcctcctgg tgacctacgt gtccgtgggc ttcgcggtcg
     7801 tcggctacgc cgggaccacc ttcctcgccg agaacgcggc cgaggaggag gccatcttcg
     7861 ccgtactcgc ccacgaggtc atgggcggct gggactgggt ggtgctcctc gcagtctgca
     7921 cctccgcgct ggcctccacc cagaccacga tcatccccgc atcccgcacc gccctgtcca
     7981 tggcccgccg acacgcgctg ccgccgcccc tctcgcacat ccacccgcgt ttcaggaccc
     8041 cggacgtgag cacgtggtgg gtggccggca tcgccatcgg ctggtacctc gtcgtcaacc
     8101 agatcagcga gaacgcgctc ctggactcgc tcaccgcgct gtccctgctc atcgccttct
     8161 actacgcgct caccggcctg gcctgtgccg tctactaccg ccgccacctg ctcgagagtc
     8221 tgcacaacct gctgttcatc ggagtcggcc cggtggtcgg cgcagccctg ctgctctggc
     8281 tgctggtgga gtcggtcggg gacatgtcca acccggagaa ttcggccacc ggtgcctcct
     8341 ggttcggtct cggcccgccc ctggtcatcg gcatcgcgat cgccgtcgcc ggcgttctgt
     8401 tcatgggcta ctggcggctg cgggacggca cgttctggca ggagcgccgc ggagtggtcg
     8461 acccggacct cgtccacggc aggaagagct gaggaggccc gatgtccgtc gtcctcggat
     8521 acgacgagtc gcccggcgcg gagcgggcgc tgcgcgtggc gctggaggtc gccaccgcct
     8581 tcggggagcc cctcgtcctc gtctacgggg cggccgcccc cggccccacc ggcgaggagt
     8641 accgggcgca ccgtgaggcc gtccgccaga cgggccgcag cgccctggcg cgcgccgtcg
     8701 aggccgccga cgaggcgggt gtgccctcgg cggtcgaggt ggtcgacgac aagcccgcgc
     8761 aggccctgct cgacgccgcc cggcgccacg acgcccgggt catcatcgta ggcacgtggg
     8821 gcgacagtcc gatccgcggc gccctgctgg gctccacccc gcacaagctc ctgcacctgt
     8881 ctccgatccc ggtgctgtgc gtgcccacgg agcacggcga gactctctga cgagtcgccg
     8941 tagtcgacca acttggccgg aaaacaggct atttcatgtg tcactatgct caatgcctga
     9001 gcgatcgagg cgttttttcg atcacggatg ggcagagtgg ggcggccgat caacaccccc
     9061 acgtgaccgc atgaccggag aaccgatgga cagcaacctc gccatccagc cccccacggg
     9121 tggccaggcg ttcgatgaag gccaagtgcg cctgtactac agccgcaaga cggctgacat
     9181 ccttcacaag tacgggccgg gaccgcgggt ccacttccac gtggggctct tcgctcccgg
     9241 cgcgacaccg aacaccaccg tctcccagcg ggtactcaag tgccgcatcg tcgagtccca
     9301 ggaggcgata gtcgagcacg cggcccgcac ctggggcgcg tacgcgactc cgcccggccg
     9361 cctcctcgac atcggctgcg gtatcggcgg cggttccctc tactgggccc aggagcacgg
     9421 cacgaaggtc accggcctca ccgtcgccgc cgaccacgtc cccgtcatcg aggacttcgc
     9481 ccgccaggcc ggcgtgtccg accgggtgac cccgctgctc gccgacatcc acacgttcag
     9541 cacccgcaag aagtacgacg ccgcgtacgc catcgagagt tccggctaca tggaccgtga
     9601 gcggctcttc gaagtcgtgg ccaagtccct gaaaccgggc ggatggttcg gaatccagga
     9661 acacttcatc tgccgtcccg agtggaccga gttcatcgac ggctactaca agacgcgcct
     9721 cggcaccctc accgaataca tcaccgccgc cgaggccgcc ggcttcgaac tggagcagga
     9781 cgaggacgtc acggaccggg tcgccgagtt ctgggtgcag tccatggcct ggaacaccgc
     9841 cgaactggac cgggtggagc ggtgcggcgc cccgtccgcc tggtcgcgcg agcggctcca
     9901 ggagtccacc atcacgcacg gcaagctgtt ccgcatctgg cgcgaccacg ctctggagac
     9961 ccggctcctg ctgttccgtc tcggcggggg caactgaccg atggcacccg tctaccgcga
    10021 ggacgcccgc ccctcccgca taggctggca gctgcccccg ttctactggc cgttcgaaag
    10081 ggatctgatc catcccaagg cggccgagct cgaggagcgg gccattgcct ggatcgacgc
    10141 tttcggcttc taccccgacg ccaccgagcg cgcctgggga ctggctaccc gcagcgtcga
    10201 cttcacctgc cggatcatcc cgtacggcga tgtggagccg atgctcctct tcgccgagtg
    10261 gaactactgg gccttcgcca ccgacgactg gcaggactca gacgccggcg ctgcgcgtac
    10321 ggcgtccgtc gtcgaccagg gcacccggct catccggacg ctcgaggcgc ccggctccgg
    10381 cctgcttccg ccggggccgc acaccgccgc gctggaagac ctggtggccc gcacccgggc
    10441 catgctcacc cctttccagc tgcgccgctt caccgagggc gtccgggact gggtgttcgg
    10501 cgccgcctca caggccgcga acgccgagcg gggcgtcatg ccgagcctca acgacttcgc
    10561 ggcgacgcgg atctcggtcg gcggcacccg gttcctcctg acctggtgcg acgtggccaa
    10621 cgggatcgac gtaccggccg aggtgctgta ttccgcgccc gtccaggccc tgaccgacgc
    10681 cgccgggttc atcgtcgcct gcgacaacga cctgttctcg tacaacaagg acgaccacca
    10741 cgagccgctg gaacagaatc tgctcaacgt gctggcccgg gactacggct gtacgcccgc
    10801 cgaagcgctg cccgccgcgt acgcgctgcg ggaccgggcg gtgacgctgt tcgtccggct
    10861 gagcgagcag ctggcgcgcg acgccgacga ccacctcggg cgctatctcg tctctgtgga
    10921 gcactggatc gcgggggaca ccgagtacca caaccgggcg ccgcgctacg ccagtccgcg
    10981 caaccgcaac gtacttcccg tcgagggggc ttcgtacggg atcacctgga gcgatacgcc
    11041 cagcgacccg agcatcgagc cgctgccgat cccggctctc gcctggtggt ggcagcagct
    11101 cgacgacgcc tcgcgctgag gtcagcggcg gccgagcagg cgcgcccacc aggagccccg
    11161 gcccgtcggc cgctcccccg gaacggggac gaccggcggg ggcgtgcggg gcgtccgggc
    11221 ggccgacctg ggtaccggcg tggagccggt gacggtgctg ccccgtgggg tgaaccggac
    11281 cgggagcgcc accaggtgac gggacatcag cgaggaagtc cactggagct cgtcctcggg
    11341 gacggccagc tccaggtcgg gcagccgggt cagcaggttg tcgatgcccg tgtccgcgat
    11401 ggcccggccg atgtcctgtc cggggcattc gtgcgggccg ctgctgaagg ccaggtggga
    11461 gcggttgccg tggacgggca ccgtcaggtc ggggcggata tccggatcga cgttgccggc
    11521 cccgaggccc agcagcagca tgtccccggc cttgatctgc gccccgccga gctcggtgtc
    11581 gccggtggcc cagcgcccga ggatcgtcat gaacggcggc tcgtcccaca ggacctgctc
    11641 cagcgcgtcc ggcagcgtca tgtgcccgcc ggagaggttc gcgcggaagc ggccgtcggt
    11701 gagcaccatg cgcagggtgt tcgcgatcag gtttgcggtc gtctcgaagg ccgcgatcat
    11761 caccaggcgc aggtgctcca cgatctcgtc gtcgctcagc gacgtcgggt gctccgtcat
    11821 ccacgtcgtg aagtcccggt tgggcaccgc ccgcttgcgc atcacgagtt cgcggaggat
    11881 gtccgagacg tactcgaagc tggccacggc cgtctcggtg ccctggagca tgtcgcgggc
    11941 ggcctcgacc aggcgcgggc cgtacgaatc cggtgccccg accagctggg tcatcaccag
    12001 catcggcagc ggctcggcga agtccgcgac gagatcgccc cgcccggact cggcgaactg
    12061 gtcgatcagc tgatcggcga agcgcttgac gtaccgtcgt atgccgcgcc ggtcgaagcg
    12121 ttccagcgac tcggtgaccg caccgcgcag ccgctcgtgc tccgcaccgt cgaccaggtg
    12181 gcacacgggc tgccatgcgg tcatcggcgt gagcgggtgg tcggccggga ccctgccctc
    12241 ctgctggtcc cgccagccgc gcgggtcccg ggagaaccgc gacggagtgc gtgccacgtc
    12301 caggttctcg cggtggccga gcaccagcca ggccggcaga tcgccctgga cgaggacggg
    12361 ggccaccgca ccgtgctcgg cacgcagctt ctcgtacagg cccatcgggt cggcctcggc
    12421 ctcggggccg tagagccggt gtgcggggca gcccggcggc ggagtgggag aggcggggga
    12481 ggggggagtg gtcacgatat ctccggggtc acggcgaggg agtgcagatg gcgcatcagc
    12541 gtcatcagga cgtcacggct ggagtcgcgc cgccgggcgt cgcagagcac cagcgggacg
    12601 gacgcgggca ggtcgagggc gctgcgcagc tcctccaccg ggtgctgggg cgcgtccggg
    12661 aaggagttga cggccaccac gaagggcacc ccgcgctcct ccagcctgcc gatcacatcg
    12721 aagctgacct ccagccggcg ggtgtcgacc aggaccaccg cgcccagcgc gccctcgaac
    12781 aggccgcgcc agaggaacca gaagcgctgc tggccggggg tgccgaagag gtacagcacc
    12841 agttcctcgt tgatgctgat ccggccgaag tccatggcca cggtggtgga cgtcttgcgc
    12901 tccacgcccg ccgtgtcgtc gacgccgacc ccggcctggg tcatcgtctc ctcggtggtc
    12961 agcggccgga tctcgctcac cgcgccgacc agggtcgtct tgccgacccc gaagccgccc
    13021 acgatcacca ccttgaccgc ggcggcggcc gtggccggca gtacgtcctc gcgccgcggc
    13081 ccggcgggcg acgcctcaga gctttcgaag tccatcgatc actgcctcaa tcaatgccag
    13141 gtcggggagt tgggcgcggg ccacgggtgc gcgggagagc acctggcccg cagtgagcag
    13201 atcgtcgatc aggacggtga ccacgctcac cggcaggccg aggtacgcgg agatctcggc
    13261 caccgagagg ggcgcctgac acagccgcat gatcgaggcg tgctccggct gcatgccggg
    13321 ccggggcccc gacttggcga cgatcagtgt gaccaggtcg aggccactgg gaactaacgg
    13381 tccgctgcga ccgccggtga tgacgtagag ccgctcgggg ctcccgtctt cccagttgtt
    13441 gcccggctcc ttcacgcggt ctgcctgtcg ctgcgcggcg ggctgctgag gtgctctccg
    13501 atccgcgcca cgaggtcacg catgcgctgg cccatcagcc ccgcgtcgac gccctcgccg
    13561 gccagtaccg ccagataggc tccggcgccc gccgccatca ggtagaagaa gccgccgtcc
    13621 atctcgatca cgaccagcct catccggccg ttgctgcccg ggagttcgga ggcgaccgcg
    13681 ccggccaggc tctgcagtcc ggcacaggcg gcggcgagcc ggtcggccgt gtcggtctcc
    13741 gcgccgtact gggccatccg caggccgtcg gcggagagca cgatgacgtg ccgggtctgc
    13801 ggaacgctct cggccaggtc cttgagcatc cagtccatat tggtctgata ctgactcatg
    13861 gctgttcccc cttgctcgcc gaggccggcg aggcgtctgt ggtctggctg tccgcgatgt
    13921 ggctcccggc ggtccggctg tccccggaca ggccgctctg gaaggcggcc agccacatcc
    13981 cgggctgtgc ttcggtccgg tccgggtcct cggcagtggt ctgcgcgacg gcggcgggcc
    14041 cgtcggaggc cgtggcacgg gccttgcggc gacgctgcgg cagcccgttc ggggtccgct
    14101 cggtcacgag ggggacctcc tcgacgaacg ccggaacctg cgggcccgtg gccggccggg
    14161 gcggctgcgg aggcgcggcc gccggctcga gggccgcgcg gggccccgag gcggtgccga
    14221 tgccgtgggc gacgccggtc gcggtcgaga cagtggtgat cagcccctgc gggacgacga
    14281 ggacggcccg taccccgccg tacgccgacg agcgcagcga gacccggaag tcgtacgcct
    14341 gcgagagccg gccgaccacg gcgaggccca gtcgcggggt ctcccccagg tcggtgaggt
    14401 cgatgccctc ctgcgcctgg cgcagcatgc gctcggcccg gttgcgggcc tcctcgctca
    14461 tgctcaggcc gccgtcctcg atctcgatcg cgatgcccga gttcacgtcg acggcggtca
    14521 gatggacctt ggtctgcggc ggcgagtagc gggtggcgtt gtccagcagc tccgccagcg
    14581 cgtggatgag cggctcgacc gccgggccca cgacggcgac ctgcgagacg gagtgcagct
    14641 ccacgcgctg gtagtcgatg atccgggaca tggcaccgcg cagcacgctg tacagcggca
    14701 cggccttgtt ccactggcgg ccgggccgcg cgccgccgag cacggcgatg gagtcggcga
    14761 gccggccgat gagcgcggtg ccgtggtcga gccggagcag atcgccgaag acggccgggg
    14821 actggccgtg ccggtcctcc atctcccgca gttcctgagc ctgttggtgc acgatcgcct
    14881 ggacgcggcg ggcgatgttc acgaaggcgc gctgcgcgga gtcgcgcagg tcctcctcgg
    14941 cgaccacggc atcgagtacc gagcgcagca ccgcgtggtg ggcggccctg aacgcggggg
    15001 tcagcccggg ctggtaggta ctggcatcct ccagggaggc gagtacgtcc tccgggaact
    15061 cgcccttgcg caggcgcccc acgacatcgg gcaacagcgc ctcggccagc cgtacggtct
    15121 cggtctgctg ccggaacagt gccgcctcct gcgccgcgac cgtggcacgc agcgccgcca
    15181 ccgccttgcc gcgccgggcg gcctcaccgc acgagagcgc gacggcgacg aaggccgcgg
    15241 caccgaccca ggccacgggg gtgcgggcag gcgcggcgac cagcgccacg gtgaccgccg
    15301 cgagcgcggc ggtcagcagg gcgggcaacg cccatacgac gggtgaggtg ggccctggac
    15361 ttccgggcga cgatccctct cgaaccatca gaaccctcaa acgatcgaaa gcgaaagatc
    15421 attggacaac agcccgggat cttatccgct gaacttgagt ctcttgacaa caggtcatga
    15481 tgcggacgtg acgcctccgt tggcgtgctg cgccgtgacc tgaaatggat ccgcgcacga
    15541 ccggtcgctc cggcgggccg ggttcgtcgt ccgcgccgtc agaacccgtg cgacgcttgc
    15601 ccgccacccc gtgcgcgagc ccggcccgac gcggcgcgac gcccctgcga ttcggctgaa
    15661 ttccatcggg cggccgggac gccgccggga actcacgtac cggcgtgcgg ggatggccgg
    15721 gggcgcaggc gtgcggccag gacggcgacg tcgtcctcgg cgtgctgcgc gtcgagcccg
    15781 tcgcagaccg cggtcacgat gtcctcgacg cgtgccccgg gtgtcatgcg cagacccgcg
    15841 agcctgtcca gtgaggtgtc gatgtcctcg ccccgccgtt ccaccaggcc gtccgtgtag
    15901 agcagcaggg tctggtcggc ggtgatcggc cgggcgaggg cctcgtagcc gccgatgccc
    15961 gttcccagcg gcgggcccac cggcacctcg agcagctcgc ccgtgccgtc gccgctgaag
    16021 acggcgggcg gcaggtgccc cgcgctcgcg tagacggcca tgccgcgggc ggggtcgatc
    16081 cgtaccagca ggcaggtcgc gggccggcgg ccctcgtccg acgcggacag ggtgtccagc
    16141 cggcgcagca cgcggtgcgg ggcgagttcg gtggaggcga cctcgcgcag gacggagcgg
    16201 taggcgttca tgtcgacggc ggcgtccagg ccgtgcccca tgacgtctcc gaccaccagc
    16261 agggtgcggc cgaagtgcag ccggacggtc tcgaaccagt cgccgccgac cagggcgcgc
    16321 agaccgaccg gaagatagcg gctggcgatg tccaggttcg ggtgcggccg ccccggttcg
    16381 gagacgaggg cccgctggag atcgagtgcc gtcttctcgg tggccgccag ccgccgcgca
    16441 tgcccgatgt ggacgctcgc gagccgcgcc gcgaagtgca gcgtggccgt ctcgtggtcg
    16501 ctgaagtcct cgccggaccg gacgacgaga agcctgccgt acgcctcgcc cccgcccggc
    16561 ccgatcagcg gtaccgagac gaggtacagg ggccggtccc cggcccgccc gctccaggtc
    16621 cgcacggaat gcccgtggtc cagggcccgg accgcggccg gggcgtcggg agaggggtct
    16681 cgcagcagat ccgtcgcgcc ggcctccgcc acccggtcgc tcaccgtgcc ccggccggtc
    16741 agatccacgg cggcggcgtc acacagcgtc cggaacagga atccggtgag ctcccggcag
    16801 gtcccccgct cgttgccgga cgtcccgatc cgctccagag cctcttccat ggcgcgcagc
    16861 cgcgcctcca agccgtcgcg ctccgacacc atgccagcgt caccccctcc cggccgtgcc
    16921 gcccgtcgag gaaggcattc catcaccgtt ccacgttttg gtgacgaatc cccgggaccg
    16981 gcgcggctcg ggctccggag gcctacagtg accgccatga cgggggcagg ggcacgcctg
    17041 gtgggcgggc gttacaggct gatcgagctg gtcggccagg gcggtatggg gcgggtgtgg
    17101 cgcggccacg acaccacgct ggaccggcag gtcgcggtca aggaggtcct gctgcccgag
    17161 ggcatcgcgc ccggcgagcg cgaggagctg ctccggcgta ccctgcgcga ggcccaggtg
    17221 gccgcccagc tcaaccaccc gggcatcatc accgtccacg acgtggtcga gcacacgggt
    17281 gcgccctgga tcgtcatgga gttcgtcgcc ggcaggtccc tcggcgctct ggtcgaacag
    17341 gacggcaggc tgccgtggga acgggtcgcg gccatcggcg cggagatggc cgacgcactc
    17401 gcgcaggccc atgccgccgg ggtcgtgcac cgggacctga agcccgacaa cgtccttctc
    17461 cagggccgcc gtacgatcat caccgacttc ggcatcgccc gggtcctgga cggttccggc
    17521 gcgacgagac tgacgcgcac ggggatcatc gtcggcaccc cccagtacat gccgcccgag
    17581 cagctcgaag gcggggacgc gggcgctccg ggcgacatgt ggtcgctggg cgccacgctg
    17641 tacgccgccg tcgagggcgc cgcccccttc gccgctccca gcctgatgtc gttgttccac
    17701 gccatcatga cgaagccgct gccaccggcc cggcacgcgg gccggctcgc cccggtcctg
    17761 gaggaactgc tcgccaagga cccggggaag cggcccaccg ccgccgcgct cgccgagcgg
    17821 ctggccgcgg tcccgcaccc gcgcacgcag ccggaccagc gccccgccga gccgcgtcag
    17881 ttgcaccacc tctccaccgt cacggcgccc gccccgcggg cgaacgcggt ccacccgccg
    17941 acccggcacg aggcgccgcc cgcccggccg tcgcctgccg cagcgccgcg gccggccccg
    18001 gccccgcccg cctcccgcac gccccgccgc cgtaccgtcc tcttcgcggg cgccgccgcc
    18061 gtcgccggcg ccaccggtgc cgtgtgggcg tggaaggccg gttcttccga cacctccgac
    18121 cggcccggta tcgccaccct ccacggccat acgtacatga tcaactcgct ggcgttcagc
    18181 cccgacggca agacgctcgc cagcgcgagc gacgacagca ccgtgcgcct ctgggacgtg
    18241 caggcacgcg cacacctggg cacgctgacc ggccacaccg acatggtctt ctccgtggcg
    18301 ttccaccccg acgggaagac catcgccacc gcgagcgccg acaagacggt gcgcctgtgg
    18361 gacaccgcgt cccgaaaggc ggtggccacc ctcggcagcc acaccgcccg agcccgggcg
    18421 gtggccttcg accccacggg gaagaccctc gccagcggcg gtcaggacaa cacggtcctc
    18481 ctgtggaacg tgacggcccg gaccaggatc agcaccctcg cggtccccgg cgaggccgtg
    18541 cacacggtgt ccttcagccc cgacgggaag acccttgccg cctccgcggg gtggggtccc
    18601 gccgcacgcc ggtgggacat gagatccatg aagagcaccg acatcgccga gaacggcggc
    18661 accacgaagt cgatctcctt cagccccgac ggaaagaccc tggccgtctc cgagccctac
    18721 cgcaccgcct ctctctggga cgtggcctcc gggaccctga ccggcacgct cgccaccgtc
    18781 cacaccgact tcgtcaacat ggtggccttc agccccgacg gcaggacgct cgccaccgcg
    18841 agcgacgaca agaccgtccg cctctgggac accgccaccc agcgcaaggc cgccaccatc
    18901 accggccacg gggaccaagt gatctccctg gcattcagcc ccgacggagc cctgctcgcc
    18961 accggcagcc gggacaagac cgtacggctg tgggccctga cctgaccatc cccgccgcac
    19021 cggtccgttg gctctcccgt ggccgaagat cgccgcctgc cgctatgcca atggcccagt
    19081 tctccgaggc ggtgttgagc cagtgggctc ccaggtggtt atctgtggcg tatccatgta
    19141 cttacggcgc cgcgcagcgc cggacggcaa cgaggccgga tccggagcgc ggcgccttcg
    19201 ccgtgcccgt ccaccgccca ccacccccgg gcggccgcgg gccggcgcgc accacagcaa
    19261 ggggggcggc gcaccgccgt gaagaggatg ttcgtggctc cggatccggg gcgtatgaga
    19321 ctgcggaact cggcccgcgc ggtgataggc gtcggcgccg ccgtggccct cgcggagctg
    19381 tgcggtctct ccctgaccgc ctccatcacc gggggactgg ccgccctgct cgccctgttc
    19441 accgtggtcg actcgagcgt gcgggcccag cgcgccacca ccgccctgct gcccctggcc
    19501 gggttccccg tcctcgcgct ggccaccacc ctgcacgggg tacccctggc ccgggacgcc
    19561 gccttcctcg ccgtcgtgtt cgccggggtc tacgcccgcc gctggggccc gcgcggccac
    19621 gccctcggca tcttcggctt catgatgttc ttcgtcaccc agttcctgca cgccgtcccc
    19681 ggacagctgc ccgagctgta cgccgccgtc gggctggctc tcctcgccgc cggtgccgtg
    19741 cgcttcgcgc tgtggcccat cgagcggcgc accccgcccg ccgccgcccc gcccgggctg
    19801 ccgggcgccg gcctcgcccg gcccaccacc cgtcaggcct tccaggccac cgccgcctgc
    19861 gccttcgccc tcgccatcgg ccaggcgctc tccgaggacc gctggtactg ggccgtgggc
    19921 accgcctggt ggatcttcgt caacacggcc tcccgcggcg agaccctcgt acggggcttc
    19981 cgccgcgtcc tcggcaccgt cctgggcatc gccgccgggc tgctgatcgc cgtaccgctg
    20041 cacggcgcgc ccgctccgac cgccgcgctc gtcgccgtgt gcgtcttcgg gatcttctac
    20101 accgcggccc cctcgtactc ctggatgatg ttcttcgtca ccgtcatggc cgggctgctc
    20161 tacgggctcc tcggcgtgct gcaccccgga ctgctgctcc tgcgcttcca ggagaccgcg
    20221 atcggcgcgt tcggcgcggc actcgccgtc gtgatcatcc tcccggtgac cacccacggc
    20281 gccaacgacg cctggatcca gcgcgccctg gagtgcgtcc gcgcctccac cgcggccgct
    20341 ctggaccggc tcgcggggga ccccgccgcc gaccccgccc cccacgccgc cgagctggaa
    20401 ctgctgctgg gccgcgtacg gatggccctc gcgcccctcg tccacccgct gagcccgctg
    20461 cgcgcccgca aggcccgggc ccggcaggtc ctggcgctgc tcgacgactg cgcccgggag
    20521 gtccgcgggt tggtcgccgt cgccgccgac ccgcaggcct cgcacgacgc ccggctggcc
    20581 gccgcctgct ggcgcgtgga ggccgccgtg caggcgctga ccgcccggga cagcaccccg
    20641 gagctcaccg ccccgccgaa gccccggccc gtcgcgcccg cggaaccggc cctcgcccac
    20701 ctgcacggcc tcgagcacgc cctcgtcgcg ctcgccgtcc cgctgcggac cgatccgcgg
    20761 gcacccctgg tcatcagcgc ctgagcagcc cctccccggc cgcctccagc cccgccggca
    20821 gccggccggc ggtgtgcacc acccccaggg cctgcgtggc ccgggtcagc gccacgtaca
    20881 ggtcgctcgg ctggaggtcg gccggctcca ccacgatcac cgtgtcgaac tccagcccct
    20941 tggcctggcg cgggtcgagg aggacgacct cccgggtcag atccggttcc gccccggccc
    21001 gtacccccgg cagctccccg gccagcgaag cgtgcagctc ccgcggcgcg atcaccgcga
    21061 gccgcccctc ggccggcatc tcccgccgca ccgcgtgggc gacggccccc gccaggtca
//
