LOCUS       NZ_CP102509            12886 bp    DNA     linear   CON 06-JAN-2024
DEFINITION  Streptomyces sp. NBC_00162 chromosome, complete genome.
ACCESSION   NZ_CP102509
VERSION     NZ_CP102509.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. NBC_00162
  ORGANISM  Streptomyces sp. NBC_00162
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8635149)
  AUTHORS   Nielsen,J.B., Gren,T., Mohite,O.S., Joergensen,T.S., Klitgaard,A.,
            Mourched,A.-S., Blin,K., Larsen,T.O., Weber,T., Gotfredsen,C.H. and
            Charusanti,P.
  TITLE     Identification of the biosynthetic gene cluster for pyracrimycin A
            and elucidation of a key reaction during its biosynthesis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8635149)
  AUTHORS   Joergensen,T.S., Gren,T., Blin,K. and Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2022) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 05-AUG-2022
            Assembly Method :: Flye v. 2.9-b1768; Polypolish v. 0.5.0; POLCA
            polisher from MaSuRCA v. 4.0.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 40.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina Nextseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/05/2024 18:03:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,275
            CDSs (total)                      :: 8,175
            Genes (coding)                    :: 7,805
            CDSs (with protein)               :: 7,805
            Genes (RNA)                       :: 100
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 371
            CDSs (without protein)            :: 370
            Pseudo Genes (ambiguous residues) :: 0 of 371
            Pseudo Genes (frameshifted)       :: 186 of 371
            Pseudo Genes (incomplete)         :: 231 of 371
            Pseudo Genes (internal stop)      :: 27 of 371
            Pseudo Genes (multiple problems)  :: 68 of 371
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:41:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2531399
            Orig. end                         :: 2544285
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102509.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Tilmann Weber, Dr.
            Professor, Novo Nordisk Foundation Center for Biosustainability,
            Kemitorvet, 220, 327D 2800 Kgs. Lyngby, Denmark.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..12886
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="19"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12886
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12886
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7886](-)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7886)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     misc_feature    32..44
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.37"
                     /tool="antismash"
     gene            complement(206..916)
                     /locus_tag="JIW86_RS11955"
                     /old_locus_tag="JIW86_11955"
     CDS             complement(206..916)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267155.1"
                     /locus_tag="JIW86_RS11955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_11955"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_215142323.1"
                     /transl_table=11
                     /translation="MGDLKQHSLIKAQERLRDQVGHALRAALIAGELRPGSVYSAPGLA
                     AELGVSATPVREAMLDLAREGLVEPVRNKGFRITEVSERDLDQYTELRTMIEVPTIGRI
                     TKIATAEQLEALRPIAQEIVTSAREHNLIGYLEADRRFHLTLLGLAGNDRLVETVGDLR
                     KRSRLYGLTGLDEAGKLVSSAEEHLELLDLMLSGDAAAAEACMVRHLGHVRSLWAQGRD
                     EPVGRTPGGLGSGV"
     misc_feature    966..976
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            complement(973..1935)
                     /locus_tag="JIW86_RS11960"
                     /old_locus_tag="JIW86_11960"
     CDS             complement(973..1935)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038315.1"
                     /locus_tag="JIW86_RS11960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_11960"
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_215142325.1"
                     /transl_table=11
                     /translation="MSGPAVIPQLTAEQTAGLLTPAAAADALAAALRGGLDPEGCPQRT
                     ALPVPGGGELLLMPAASGTYAGVKIAGVAPGNPARGLPRITGSYLLLDGPTLRPLALLD
                     GAALTALRTPAVSALALRHLAPAGRPLRLVLFGSGPQAYGHLEATLAVRELAEVVVVAR
                     RPEGAEKLAAHARSLGPAARTGTPEDVAGADLVVCCTTAREPLFDGRLVGPGATVVAVG
                     SHEPEARETDTALVRRAAVYVESRAAALREAGDLLVPEAEGAIGPGHITGTLADLVTGR
                     MPVGGTPGCPQLFKSVGMAWEDLAVAVALFQAAGASSET"
     gene            complement(1932..2948)
                     /locus_tag="JIW86_RS11965"
                     /old_locus_tag="JIW86_11965"
     CDS             complement(1932..2948)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018844380.1"
                     /locus_tag="JIW86_RS11965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_11965"
                     /product="proline racemase family protein"
                     /protein_id="WP_257553738.1"
                     /transl_table=11
                     /translation="MSTVRTVDYHTAGEPFRIVDCGAEGLAVPGDTVAERCATAIGPGG
                     SGTAPRRGALDDVRRLLVQEPRGHAGMYGGFVVPPDDDGAHFGVLFWHKDGYSTACGHG
                     AMALGVWAVDTGRVAAPDDGDAQVRIDVPSGRVTATVHRDGGRTTGVTFRNVPARVSAR
                     KVPVATTLGMAEVDLAHAGACYASVAARDLGLDVSRASLPALVRAGQEIRAALATHPAT
                     WHPDGPLLSGVYGVILYEELPGTPFGPHQRNVTVFADGQIDRSPCGSGTSTRLALLAED
                     GRLGPGEDLLHESVMGTVFTGRMLPGGVTEVTGTAYRTGEHAFTADPYDALGAGFLL"
     gene            complement(2945..3949)
                     /locus_tag="JIW86_RS11970"
                     /old_locus_tag="JIW86_11970"
     CDS             complement(2945..3949)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891275.1"
                     /locus_tag="JIW86_RS11970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_11970"
                     /product="proline racemase family protein"
                     /protein_id="WP_257553739.1"
                     /transl_table=11
                     /translation="MRTRHVYHAVDSHTEGMPTRVITGGIGVIPGATMAEKRLHFIEHT
                     DHVRTLLMYEPRGHAAMSGAILQPPTRPDADFGVLYIEVSGLLPMCGHGTIGVATVLVE
                     TGMVPVVEPVTTVRLDTPAGLVSVDVRVEDGAATAVTLTNVPSFCVGLDLKAEVPGFGT
                     VTYDLAYGGNFYAFVELDDLGLPFDRARKDELLTAGLAIMDAINGSGDRPVHPENPSIA
                     GVKHVYLAAPGSDARRSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGLLELGADFVNE
                     SFIGTEFTGRLVGETTVGGLPAVVPTVTGRAWITGTAQYFLDPADPFPGGFLL"
     gene            complement(3986..4924)
                     /locus_tag="JIW86_RS11975"
                     /old_locus_tag="JIW86_11975"
     CDS             complement(3986..4924)
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267151.1"
                     /locus_tag="JIW86_RS11975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_11975"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_257553740.1"
                     /transl_table=11
                     /translation="MTHAPTPAPRPATGTDTRTRPWHGIMVATALPLREDLSVDYDAYA
                     EHVAWLIANGCDGVVPNGSLGEYQTLDDEERARVVRTAVEAAGDGSRVMPGVAAYGSAE
                     ARRWAEQAAEAGAGSVLLLPPNAFRADEETVRAHYAEVARAGLPVVAYNNPYDTKVDLV
                     PALLARLHADGSIVAVKEFSGDVRRAYEIAELAPGLDLLIGADDVLLELALAGAVGWIA
                     GYPNALPQSCATLYRAAVAGDLATALPLYKSLHSLLRWDSKTEFVQAIKLSMDLAGRPG
                     GATRPPRFPLTGDTEAAVRAATEKALAEGLN"
     misc_feature    complement(4948..4958)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    4948..4964
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     misc_feature    4965..4979
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     gene            complement(5001..6419)
                     /locus_tag="JIW86_RS11980"
                     /old_locus_tag="JIW86_11980"
     CDS             complement(5001..6419)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038323.1"
                     /locus_tag="JIW86_RS11980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_11980"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_257553741.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.7e-27, bitscore:
                     93.3, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 6.9e-12, bitscore:
                     44.4, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTSPSEPDASGPADLADLAVVGAGPAGLAAAVTAAGLGLRVTLL
                     DAGEQPGGQFYRHPAPGLGAARPEALHHAWPEFATREAALRAHVSAGRITYLTAHHVWT
                     VVPDGGHWVLHAVAGPEERAAAVHARALLIATGAYERQLPFPGWTLPGVVGAGGAQAML
                     KAGLVLPGKRVVVAGSGPLLLAVAGSLAAAGATVPAVVEAAAYIAYAARTPVLLRNPGK
                     LAEAAAYGAALARHRIRLLTRHAVTEAHGTDRVEAVTVARLDRDWRPLPGTARRIPCDA
                     LAVGHGLVPQLELATGLGCATRRSPDGTVALELDAGMRTSVPGVWSAGETGGIGGAGLA
                     LAEGEIAAHSIAGRPAPAGLVRRRARLRAFADAMGAAHRPGPGWTGWLRDDAVVCRCEE
                     VPAGRIREAAGELGARDARTVKLLTRAGMGWCQGRMCGPAVAALAGEAPAPDRRPLSCP
                     VPLRLLAELPPDAH"
     gene            complement(6400..6729)
                     /locus_tag="JIW86_RS11985"
                     /old_locus_tag="JIW86_11985"
     CDS             complement(6400..6729)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309276.1"
                     /locus_tag="JIW86_RS11985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_11985"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_257553742.1"
                     /sec_met_domain="Fer2_4 (E-value: 1.2e-23, bitscore: 81.8,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAHDRDRTPRSLVGGSPLSAHTIGFDGRELPAQEGQSIAAVLWS
                     AGILAWRTTREGGAPRGAFCGIGSCYDCLVTVNGRPNQRACLVPARPGDTVTTQEGTGH
                     ADLAV"
     gene            complement(6726..7886)
                     /locus_tag="JIW86_RS11990"
                     /old_locus_tag="JIW86_11990"
     CDS             complement(6726..7886)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642316.1"
                     /locus_tag="JIW86_RS11990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_11990"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_257553743.1"
                     /sec_met_domain="DAO (E-value: 2.4e-65, bitscore: 220.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKRHSLDAVIIGAGVVGAACAYYAARAGLSVAVVDRGPVAGGTT
                     GAGEGNLLVSDKEAGPELDLALLSTGLWRELAAVLPQEIEYEAKGGLVVAPDQASLEAL
                     RSFAEGQRKAGVDAIEAAAGDLRTLEPHLAPGLAGGFRYPQDAQVQPAQAAARLLAASG
                     AEVHLGEEVTGFVRSGEAVCGVRTARRELLAPAVVNAAGTWAGAVAELAGVSLPVLPRR
                     GFVLVTEPLPRMVRHKVYAADYIADVASGSAALQSSAVVEGTPAGPVLIGATRERVGFD
                     RTLSTEALRRLAAQAAALFPVLADVRVLRTYHGFRPYLPDHLPAIGPDPRRPGLLHACG
                     HEGAGIGLAPATGALIAAALTGAEPAVSLAPFRPDRFPDRAAEASR"
     gene            complement(7957..10326)
                     /locus_tag="JIW86_RS11995"
                     /old_locus_tag="JIW86_11995"
     CDS             complement(7957..10326)
                     /EC_number="3.4.24.3"
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267147.1"
                     /locus_tag="JIW86_RS11995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_11995"
                     /product="collagenase"
                     /protein_id="WP_257553744.1"
                     /transl_table=11
                     /translation="MSKHRAVRSSLLASAVAVTLLASAGQATTQAAEAPVPATFAGAQT
                     DPAPAANPFDEVDHLANAPETTPAPAPAPGGQALTGQIPGAATAASAPAERTEKSRKAA
                     AQTAPTARSVAAGVPCTLDGITSLGPEQFADFLADQAVLADGCLRGLIWTWDARLAPVM
                     SDAHVQAVSRRISGLAAAHDGRNSSHLEEMFTYLHAVAYHDYSRDEIDVTDAPTVNAMR
                     QAIADFGSAAHTFDVTASNARTLREALYAGSAPSLRQHQLGLIKKVLATMDPAHPATHL
                     DAGWAGAALAGLSVNYLGVYDGNHDTAFQAAVAADPAYRAVFKAFSGYTHLKGTGNAWV
                     VRDALGEYGRFGQIPALKDQVVADLGALLGPVKSAFGSEPWAKLVSWLNYYQACKQYGV
                     CKEDIEKQLFPNTFTYDNGAIKVRTALDRATVDQLYYASKQVKTQYHRVLGTDQPLAGD
                     PNTTLNIVLYASRADYENYHPILTGYGTNNGGIYIENGATFYTYQRRVPQDSSLTLEEL
                     FRHEYTHYLNGRFAVPGFFGEGPWYEGDRTTAMDEGTAEFFDGATRDNGIAVRKSLVKS
                     IISDTSGGGPRMSVEQLLNATYDGDGFRFYSYAGTFFEFLWTEKPTLLREMYTHLRNND
                     VAAYDAWRHRMGADTYLQRDYDRFLDAQIAKVDQLFVPNTSFTPNDQLRDSALASVKSS
                     FATATYSTPDCVENGDPGKRRFTCTGRITANLKNWRSDDQNFKDMSETVDYFILDRSGT
                     ASNNLADMNCSFGPVEIWSNKVAGTSSYSCEGPLRS"
     misc_feature    10395..10408
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    complement(10438..10454)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.29"
                     /tool="antismash"
     misc_feature    complement(10440..10450)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            10502..11872
                     /locus_tag="JIW86_RS12000"
                     /old_locus_tag="JIW86_12000"
     CDS             10502..11872
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743074.1"
                     /locus_tag="JIW86_RS12000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_12000"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_257553745.1"
                     /transl_table=11
                     /translation="MTDTPSRLHTGSHDLPVSPELSRFMADNWAASPLPGSVRVPGHAV
                     TPARRARLSARFPGERLIVPAGGLKVRSNDCDHRFRPHSAYAWLTGLTGEDQAGHVLVM
                     EPSGPHAHEAVLYLRPRSPRADGNEEFFRDRRYGEFWVGRRPDLAEAERLTGIRCAHLD
                     LLGSPAGRDASTDAELAAALSELRLVKDAWEVEQLQLAVDHTTAGFEDVVRALPRALAH
                     PRGERWIEGVFGLRARAEGNGTGYETIAASGAHACTLHWIRNDGRLNGDELLLLDAGVE
                     TDTLYTADITRTLPLSGRFTSVQRQVYELVLAAQEAGMAALRPGASFGDFHRAGMRVIA
                     EGLAEWGVLKDAAGDLHRRYTLCSSGHMLGLDVHDCAKARAETYLEGVLEEGQVLTVEP
                     GLYLQPDDETLPPELRGIGVRIEDDLVITADGARLMSGALPRTVAGIEEWMGRLLEG"
     gene            complement(11869..12777)
                     /locus_tag="JIW86_RS12005"
                     /old_locus_tag="JIW86_12005"
     CDS             complement(11869..12777)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003960257.1"
                     /locus_tag="JIW86_RS12005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_12005"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_257553746.1"
                     /transl_table=11
                     /translation="MDVDLRDLELLDATAEAGSLTAAAERLYVSQPALSQRLTRLEARL
                     GMQLFDRKGRRLVPNAAGRRLLVAARQILGELESASRDLREIRDGHGRRVRFTAQCSTT
                     FPWLPPVLRAFREREPDIDVRIEAVADDAPIPALLADLVDVALVTKPDLQMDRVSLTKL
                     FDDEMMAVVPAGHPWASRGHLTARDFDGADLVLYDGYDQNRIPSMPLPIPAGARPGRIT
                     TMPVVTDLVIEMVAGGQGVTVLPNWVAAPYVSSHGLALVRIGEQPLTRTWFCATRTGPR
                     PPHLEAFVEELTTRLTAPISG"
ORIGIN
        1 gtgaccagga cggcggcgga agcgatccga attgcagtct tcaacacggt cggcacaacc
       61 tcttcgctcg gtgcacagga ctcggtgtta ttagccgaat ttccgacgca accgaccttc
      121 gtccgcatcc gtcacccggt ggcaccacga ggcccacccg cccggcgcag gccgccggcc
      181 cggcgaaccc tcccgttcac ccgtgctaga cgccggagcc gaggcctccc ggggtgcggc
      241 caacgggctc gtcgcggccc tgggcccaca gggagcggac gtggccgagg tggcggacca
      301 tgcaggcctc ggccgccgcg gcgtcaccgg agagcatcag gtcgagcagt tcgaggtgct
      361 cctccgccga ggacaccagc ttgccggcct cgtccagacc ggtcagcccg tacagccggg
      421 accgcttgcg caggtcgccg accgtctcga cgaggcggtc gttgcccgcg agcccgagca
      481 acgtgaggtg gaagcggcgg tccgcctcca ggtagccgat caggttgtgc tcgcgggcgc
      541 tggtgacgat ctcctgcgcg atgggacgca gcgcctccag ttgctcggcc gtggcgatct
      601 tcgtgatccg cccgatggtc ggcacctcga tcatcgtgcg cagctcggtg tactggtcga
      661 ggtcgcgctc gctgacctcg gtgatgcgga accccttgtt gcggacaggt tcgaccaggc
      721 cctcgcgggc gaggtcgagc atcgcctcgc gcaccggcgt ggccgaaacg ccgagttcgg
      781 ccgcgagccc gggggcggag tagacgcttc cggggcgcag ctcacccgct atcagggctg
      841 ctcggagggc gtggccgacc tggtcgcgga gccgttcctg ggccttgatg agactgtgct
      901 gcttcaggtc acccattgca tttcctccga gacgccctac accggcgatg ggcagaggaa
      961 cagcgtacaa tgtcacgttt cgctgctcgc cccggcggcc tggaacagcg cgaccgccac
     1021 ggcaagatct tcccaggcca tgcccacact cttgaagagc tgtggacaac ccggcgtccc
     1081 gcccacgggc atccggcccg tgacgaggtc cgcgagggtg ccggtgatgt ggccgggccc
     1141 gatggcgccc tcggcctccg ggaccagcag gtcccccgcc tcgcgcaggg ccgccgcgcg
     1201 cgactccacg tacaccgccg cgcgtcgcac gagggcggtg tccgtctccc gggcctccgg
     1261 ctcgtgcgaa ccgacggcga cgaccgttgc cccggggccc accagccgcc cgtcgaagag
     1321 gggttcccgg gccgtggtgc agcagacgac cagatcggcg ccggccacgt cctcgggggt
     1381 gcccgtgcgg gcggccgggc ccaggctgcg ggcgtgcgcg gcgagcttct ccgcgccctc
     1441 gggcctgcgg gcgacgacca ccacctcggc caactcccgt accgcgagcg tcgcttcgag
     1501 gtgcccgtac gcctgcggac ccgagccgaa gagcaccagt cgcagcggcc gcccggccgg
     1561 cgccaggtgg cgcagcgcga gggcggagac cgccggggtg cgcagggcgg tcagcgccgc
     1621 gccgtcgagc agggcgagcg ggcgcagggt cggcccgtcc agcagcaggt aggacccggt
     1681 gatccggggc agcccgcgag ccggattgcc cggcgcgacc ccggcgatct tcaccccggc
     1741 gtacgtcccg gacgcggccg gcatcagcag cagttcgcca ccgccgggta cggggagggc
     1801 ggtgcgctgc gggcagccct ccgggtcgag gccgccccgc agggcggcgg ccagtgcgtc
     1861 ggccgcggcg gccggggtga gcagcccggc cgtctgctcg gcggtcagtt gcgggatcac
     1921 agcaggtccg ctcatagcaa aaaccccgcg ccgagggcgt cgtacgggtc ggccgtgaag
     1981 gcgtgttcac cggtgcggta ggcggtgccg gtgacctcgg tgacgccacc ggggagcatc
     2041 cgtccggtga acaccgtgcc catgaccgac tcgtgcagca ggtcctcgcc cggaccgagc
     2101 cgcccgtctt ccgcgagcag cgcgagccgc gtcgaggtgc ccgagccgca gggcgagcgg
     2161 tcgatctgac cgtcggcgaa gacggtgacg ttgcgctggt gcggcccgaa gggagtgccg
     2221 gggagctcct cgtacaggat caccccgtag accccggaca ggagcgggcc gtcggggtgc
     2281 caggtggccg ggtgggtggc cagcgcggca cggatctcct ggccggcccg cacaagcgcg
     2341 ggcagcgagg cccgggagac gtcgaggccg aggtcgcggg cggcgaccga ggcgtagcag
     2401 gccccggcgt gcgcgaggtc cacctccgcc atgccgaggg tggtcgccac cggcaccttg
     2461 cgggcgctca cccgggccgg gacgttgcgg aaggtgacac cggtggtgcg gcccccgtcc
     2521 cggtgcacgg tcgcggtgac ccggcccgac ggcacgtcga tgcgcacctg ggcgtccccg
     2581 tcgtcgggtg cggcgacccg gccggtgtcc acggcccaga cgccgagggc catggcgccg
     2641 tggccgcagg cggtggagta gccgtccttg tgccagaaga gcaccccgaa gtgggccccg
     2701 tcgtcgtcgg gcgggacgac gaagcccccg tacatcccgg cgtgcccgcg cggctcctgc
     2761 accagcaggc gccgtacgtc gtccagtgcc ccgcggcgcg gtgcggttcc ggatcctccg
     2821 gggccgatgg cggtggcaca gcgttcggcg acggtgtcac cgggcacggc caggccctcc
     2881 gcgccgcagt cgacgatgcg gaagggctcg ccggcggtgt ggtagtccac cgttcggacg
     2941 gtgctcacag caggaagcct ccggggaagg ggtcggccgg gtcgaggaag tactgggcgg
     3001 tgcccgtgat ccaggcccgg ccggtgacgg tggggaccac ggccgggagc ccgccgacgg
     3061 tggtctcgcc gacgaggcgg ccggtgaact cggtgccgat gaaggactcg ttgacgaagt
     3121 ccgcgccgag ctccagcagg ccgcgggcgt gcagctgggc catgcgcgcg ctggtgcccg
     3181 taccgcaggg cgagcggtcg aaccagcccg ggtggatggc catcgcgtgc ctggagcggc
     3241 gggcgtcgga gccgggggcg gcgaggtaga cgtgcttgac cccggcgatg gaggggttct
     3301 cggggtggac gggccggtcc ccggagccgt tgatcgcgtc catgatcgcg agcccggcgg
     3361 tgagcagctc gtccttgcgg gcgcggtcga aggggagccc gaggtcgtcg agttcgacga
     3421 aggcgtagaa gtttccgccg taggcgaggt cgtaggtgac cgtgccgaag ccggggacct
     3481 cggccttcag gtcgagccct acgcagaagg acgggacgtt ggtgagggtg accgcggtgg
     3541 ccgcgccgtc ctccacccgg acgtcgacgc tcaccagtcc ggccggggtg tcgagccgga
     3601 cggtggtgac cggctcgacg acgggcacca tgccggtctc gaccagcacg gtggccaccc
     3661 cgatggtccc gtgcccgcac atcggcagca ggcccgacac ctcgatgtag agcacgccga
     3721 agtcggcgtc gggccgggtg ggcggctgga ggatggcgcc gctcatcgcg gcgtgcccgc
     3781 gcggctcgta catgagcagc gtccgcacgt ggtccgtgtg ctcgatgaag tggagccgct
     3841 tctcggccat cgtggcgccg gggatcaccc cgatgccccc ggtgatgacg cgggtcggca
     3901 tgccctcggt gtgcgagtcc accgcgtggt agacgtggcg cgtacgcatg gagtcccctc
     3961 cgacagggtg ttatccgaca gggtgctagt tgagaccctc ggcgagggcc ttctcggtgg
     4021 cggcgcggac ggcggcctcg gtgtcgccgg tgagcgggaa gcgcggcggg cgggtggcgc
     4081 cgccggggcg gcccgccagg tccatggaga gcttgatggc ctggacgaac tcggtcttgg
     4141 agtcccagcg cagcagggag tgcagggact tgtagagcgg cagggcggtg gcgaggtcac
     4201 cggcgacggc ggcccggtag agggtggcgc aggactgcgg cagggcgttg gggtagccgg
     4261 ctatccagcc gacggcgccc gcgagggcga gttcgaggag gacgtcgtcg gcgccgatga
     4321 gcaggtccag gccgggggcg agttcggcga tctcgtaggc gcggcgcacg tccccgctga
     4381 actccttgac ggcgacgatg gatccgtcgg cgtgcagccg ggccagcagg gccgggacca
     4441 ggtcgacctt ggtgtcgtac gggttgttgt acgcgacgac gggcagcccg gcgcgggcga
     4501 cctcggcgta gtgggcgcgt acggtctcct cgtcggcccg gaaggcgttg gggggcagca
     4561 ggagtacgga gccggccccg gcctcggcgg cctgctcggc ccagcggcgg gcttcggcgc
     4621 tgccgtaggc ggcgactccg ggcatgacgc gggatccgtc gcccgcggcc tcgacggcgg
     4681 tacggacgac gcgggcccgc tcctcgtcgt cgagggtctg gtactcgccg agggagccgt
     4741 tggggaccac gccgtcgcag ccgttggcga tcagccaggc cacgtgctcg gcgtaggcgt
     4801 cgtagtcgac gctgaggtcc tcgcgcaggg gcagcgcggt ggcgaccatg atgccgtgcc
     4861 aggggcgggt gcgggtgtcc gtgccggtgg ccgggcgggg cgcgggggtg ggcgcgtggg
     4921 tcatgaggtg actccctagt gtggtgtgtg acattttact agtgggtgcg agtcggccac
     4981 aagggccggg gacggtccga tcagtgcgcg tccgggggaa gttcggcgag caggcgcagc
     5041 gggaccgggc aggacagcgg ccgccggtcg ggcgccgggg cctcaccggc gagggcggcc
     5101 acggccgggc cgcacatccg gccctggcac cagcccatgc ccgcccgggt gaggagtttg
     5161 accgtacggg cgtcccgcgc gccgagttcc ccggcggcct cgcggatccg gccggccggc
     5221 acctcctcgc agcggcacac gacggcgtcg tcccggagcc agccggtcca gccggggccc
     5281 gggcggtggg cggcgcccat cgcgtcggcg aaggcgcgca gccgcgcgcg gcggcggacg
     5341 agcccggcgg gggcgggccg tccggcgatc gagtgggccg cgatctcccc ttcggcgagg
     5401 gcgagtccgg cgccgccgat gccgcctgtc tcgcccgcgg accagacacc ggggacggag
     5461 gtccgcatcc cggcgtccag ctcgagggcc acggtgccgt cggggctgcg gcgggtggcg
     5521 cagccgaggc cggtggcgag ctccagctgg ggcaccaggc cgtggccgac ggcgagggcg
     5581 tcgcagggga tccggcgggc ggtaccgggc agcgggcgcc agtcgcggtc gaggcgggcg
     5641 acggtgacgg cctcgacccg gtcggtgccg tgggcctcgg tgacggcgtg ccgggtgagg
     5701 aggcggatgc ggtgcctggc cagcgcggcg ccgtaggcgg cggcctcggc gagcttgccg
     5761 gggttgcgca gcagcaccgg ggtccgggcg gcgtacgcga tgtaggcggc ggcctcgacg
     5821 accgcgggga cggtggctcc cgcggcggcg agggacccgg ccaccgcgag cagcagcggg
     5881 ccgctcccgg cgacgaccac gcgcttgccg ggcagtacga gcccggcctt gagcatggcc
     5941 tgggccccgc cggccccgac gaccccgggc agggtccagc cggggaaggg cagttggcgc
     6001 tcgtaggcgc cggtggcgat gagcagggcg cgggcgtgga ccgccgccgc gcgctcctcc
     6061 ggccccgcga cggcgtgcag cacccagtgg ccgccgtccg gcaccacggt ccacacgtgg
     6121 tgggccgtca ggtacgtgat gcggcccgcc gacacgtggg cgcgcagggc ggcttcgcgg
     6181 gtggcgaact cgggccaggc gtggtggagg gcctcggggc gggcggcgcc gaggccgggc
     6241 gcggggtgcc ggtagaactg cccgccgggc tgctcccccg cgtcgaggag ggtgacgcgc
     6301 aggccgaggc cggcggccgt gacggctgcg gccaggccgg ccggtccggc gccgacgacg
     6361 gcgaggtcgg cgaggtcggc gggcccggag gcgtccggct cagacggcga ggtcggcatg
     6421 gccggttccc tcctgggtgg tgacggtgtc ccccggtcgg gcggggacca ggcaggcccg
     6481 ctggttcggg cggccgttga cggtgacgag gcagtcgtag cagctgccga tcccgcagaa
     6541 ggcgccgcgc ggggcgccgc cctcgcgggt ggtgcgccag gcgaggatcc cggccgacca
     6601 cagcacggcg gcgatggact ggccctcctg cgcaggcagt tcgcggccgt cgaagccgat
     6661 ggtgtgggcg gacaacgggc tgccgccgac gagcgagcgg ggggtgcggt cgcggtcgtg
     6721 tgccttcatc gggacgcctc cgcggctcgg tcgggaaatc ggtcgggacg gaacggggcc
     6781 agggagaccg ccggttcggc tcccgtcagg gcggctgcga tcagggcgcc ggtggccggg
     6841 gccaggccga tgcccgcgcc ctcgtgcccg caggcgtgca gcagtccggg acggcgcggg
     6901 tccgggccga tcgccgggag gtggtcgggg aggtaggggc ggaagccgtg ataggtgcgc
     6961 agcacccgga cgtccgcgag gaccgggaag agggccgccg cctgggcggc gaggcggcgc
     7021 agggcctccg tggacagggt gcggtcgaag ccgacgcgtt cgcgggtggc cccgatcagg
     7081 accgggcccg ccggggtgcc ctcgaccacg gccgaggact gcagggccgc ggagccgctg
     7141 gcgacgtccg cgatgtagtc ggcggcgtag accttgtgcc ggaccatcct gggcagcggc
     7201 tcggtcacca gcacgaagcc gcggcgcggg aggacgggca ggctcacgcc cgcgagctcc
     7261 gcgacggccc cggcccaggt gcccgccgcg ttcaccacgg cgggggccag gagttcgcgg
     7321 cgcgcggtgc ggaccccgca gacggcctcg ccggagcgca cgaagcccgt cacctcctcg
     7381 ccgaggtgga cctcggcgcc cgacgcggcc agcagccggg ccgccgcctg ggcgggctgg
     7441 acctgggcgt cctgcgggta gcggaagcct cccgcgaggc ccggggccag atggggctcc
     7501 agggtgcgca ggtcgccagc cgccgcctcg atcgcgtcga ccccggcctt gcgctggcct
     7561 tcggcgaagc tccgcagggc ttcgagcgaa gcctggtccg gggcgacgac gaggccgccc
     7621 ttggcctcgt actcgatctc ctgcgggagg acggcggcga gctcgcgcca cagcccggtg
     7681 gagagcaggg cgaggtcgag ctccgggccc gcctccttgt cggagacgag caggttgcct
     7741 tcgccggcgc ccgtcgtgcc gcccgcgacc gggcctcggt cgaccacggc cacggagagt
     7801 ccggcgcggg ccgcgtagta cgcgcacgcc gctccgacga cgccggcgcc gatgatgacg
     7861 gcgtccaggg agtgtctctt gagcacgaca gtaatatgtc acattcttta gtggctgccc
     7921 agaccggccc tccgaggagg gccggtccgg tagggatcag ctgcggagcg ggccctcaca
     7981 gctgtaactc gacgtacccg ccaccttgtt cgaccagatc tccaccggcc cgaaggagca
     8041 gttcatgtcg gccaggttgt tggaggccgt accggagcgg tcgagtatga agtagtcgac
     8101 cgtctcggac atgtccttga agttctggtc gtcactgcgc cagttcttca ggttcgcggt
     8161 gatccgcccg gtacaggtga agcggcgctt gccggggtcg ccgttctcca cgcagtccgg
     8221 ggtgctgtag gtggccgtgg cgaaggagga cttcaccgag gccagcgccg agtcgcgcag
     8281 ctggtcgttg ggggtgaagg aggtgttcgg cacgaagagc tggtccacct tggcgatctg
     8341 cgcgtccagg aagcggtcgt agtcgcgctg gaggtaggtg tcggcgccca tccggtggcg
     8401 ccaggcgtcg tacgccgcga cgtcgttgtt gcggaggtgg gtgtacatct cacgcagcag
     8461 cgtgggcttc tcggtccaca ggaactcgaa gaaggtgccg gcgtagctgt agaagcggaa
     8521 gccgtcgccg tcgtaggtgg cgttcagcag ctgctcgacg gacatgcgcg ggccgccgcc
     8581 cgaggtgtcg ctgatgatgc tcttgaccag ggacttgcgg acggcgatgc cgttgtcgcg
     8641 ggtggcgccg tcgaagaact cggccgtgcc ctcgtccatg gcggtcgtac ggtcgccctc
     8701 gtaccagggg ccttcgccga agaagccggg gacggcgaag cggccgttga ggtagtgcgt
     8761 gtactcgtgg cggaagagct cctcgagggt gagggaggag tcctgcggga cgcggcgctg
     8821 gtaggtgtag aaggtggcgc cgttctcgat gtagatgcca ccgttgttgg tgccgtagcc
     8881 ggtcaggatc gggtggtagt tctcgtagtc ggcgcgggag gcgtagagca cgatgttcag
     8941 ggtggtgttg gggtctccgg cgagcggctg gtccgtgccg aggacccggt ggtactgggt
     9001 cttgacctgc ttgctggcgt agtagagctg gtcgacggtg gcccggtcga gggcggtgcg
     9061 gaccttgatg gcgccgttgt cgtaggtgaa ggtgttcggg aagagctgct tctcgatgtc
     9121 ctccttgcag accccgtact gcttgcacgc ctggtagtag ttgagccagg agacgagctt
     9181 ggcccacggc tcgctgccga aggcggactt caccggcccc agcagggcgc cgaggtcggc
     9241 gacgacctgg tccttgaggg ccgggatctg gccgaagcgg ccgtactcgc cgagtgcgtc
     9301 gcgcaccacc caggcgttgc cggtgccctt gaggtgggtg tagcccgaga aggccttgaa
     9361 gaccgcgcgg tacgcggggt cggccgccac cgccgcctgg aaggcggtgt cgtggttgcc
     9421 gtcgtagacg ccgaggtagt tgacggagag gccggcgagc gccgcgcccg cccagccggc
     9481 gtccaggtgg gtggccgggt gggccgggtc catggtggcc aggaccttct tgatgaggcc
     9541 cagctggtgc tggcgcaggc tcggtgcgct gccggcgtag agggcctcgc gcagggtgcg
     9601 ggcgttggag gccgtgacgt cgaaggtgtg ggcggcgctg ccgaaatcgg cgatggcctg
     9661 gcgcatggcg ttcacggtcg gcgcgtcggt gacgtcgatc tcgtcgcgcg agtagtcgtg
     9721 gtaggcgacc gcgtgcaggt aggtgaacat ctcctccagg tgggaggagt tgcggccgtc
     9781 gtgggcagcg gccaggccgg atatccgacg cgagacggcc tggacgtgcg catcggacat
     9841 cacgggggcc aggcgggcgt cccaggtcca gatcaggccg cgcaggcagc cgtcggcgag
     9901 gacggcctgg tcggcgagga agtcggcgaa ctgctccggg ccgaggctgg tgatcccgtc
     9961 gagggtgcag gggacgcccg ccgcgacgct ccgtgcggtg ggggccgtct gggccgccgc
    10021 cttgcggctc ttctcggtgc gctcggcggg cgcggaggcg gccgtggccg cgccggggat
    10081 ctgcccggtg agggcctgcc cgccgggggc cggggcgggg gcgggggtcg tctcgggggc
    10141 gttggcgagg tggtcgacct cgtcgaacgg gttcgcggcg ggcgccgggt cggtctgggc
    10201 cccggcgaac gtggccggca ccggggcttc cgcggcctgc gtggtggcct gcccggcgga
    10261 ggcgaggagc gtcacagcga cggcggaggc gaggagggac gagcgcacag ctctgtgctt
    10321 ggacaccgag aactcctggt tggagagggt gaggtggggg gtggtgcgtt gaacggccct
    10381 gcgtcacacg gcgtttgacg gggattaacg tgccgaggtg tgagctgtaa catagtaatg
    10441 tgaaattgca ctgacaagac ctgtgcgacc cccagttcgc atcttcttga gggagccccc
    10501 cgtgaccgac actccatccc gcctccacac gggcagccac gacctgcctg tatcaccgga
    10561 gttgtcccgt ttcatggcgg acaactgggc cgcctccccg ctgcccggct ccgtccgcgt
    10621 ccccggccac gccgtcaccc cggcccgtcg ggcgcggctc tcggcccgct tcccgggcga
    10681 gcggctgatc gtcccggccg gcgggctgaa ggtccgctcc aacgactgcg accaccgctt
    10741 ccgaccgcac agcgcctacg cctggctgac gggcctgacc ggcgaggacc aggcgggcca
    10801 cgtcctggtc atggaaccct cgggcccgca cgcccacgag gcggtgctgt acctgcggcc
    10861 gcgctcgccg cgggcggacg ggaacgagga gttcttccgc gaccgccggt acggggagtt
    10921 ctgggtgggc cgccgcccgg acctggcgga ggcggaacgc ctcaccggga tccgctgcgc
    10981 gcacctggac ctgctcgggt ccccggccgg ccgcgacgcg tccaccgacg ccgaactcgc
    11041 cgccgccctc tcggagttgc gcctggtgaa ggacgcctgg gaggtcgagc agctccagct
    11101 ggcggtcgac cacacgacgg cggggttcga ggacgtcgta cgggcactgc cgcgcgccct
    11161 ggcgcacccg cgcggggagc ggtggatcga gggggtcttc ggcctgcgcg cccgggccga
    11221 gggcaacggc accgggtacg agaccatcgc ggcgtccggc gcgcacgcgt gcacgctgca
    11281 ctggatccgc aacgacggcc ggctgaacgg ggacgaactg ctgctcctgg acgcgggcgt
    11341 ggagacggac accctgtaca cggcggacat cacccgcacc ctcccgctgt cgggccgttt
    11401 cacctccgtc cagcggcagg tgtacgaact ggtcctggcc gcccaggagg cgggcatggc
    11461 cgcgctgcgt cccggggcga gcttcgggga cttccaccgg gccgggatgc gggtgatcgc
    11521 ggagggcctg gcggagtggg gcgtcctgaa ggacgcggcg ggcgacctgc accggcggta
    11581 caccctgtgc agcagcgggc acatgctggg cctggacgtc cacgactgcg cgaaggcgcg
    11641 ggcggagacc tacctggaag gggtcctgga ggagggtcag gtcctcacgg tggagccggg
    11701 cctgtacctc cagccggacg acgagaccct cccgccggag ctgcgcggca tcggggtccg
    11761 catcgaggac gacctggtca tcaccgcgga cggcgcccgc ctgatgtcgg gcgccctgcc
    11821 ccgcacggtg gcggggatcg aggagtggat gggccgcctg ctggagggct aaccgctgat
    11881 cggggcggtg aggcgggtgg tgagttcctc gacgaaggcc tcgaggtggg gcgggcgcgg
    11941 cccggtccgg gtggcgcaga accacgtacg ggtcagcggc tgctcgccga tgcggaccag
    12001 cgcgaggccg tgcgaggaca cgtagggggc ggccacccag ttggggagca ccgtcacgcc
    12061 ctggccgccc gccaccatct cgatcaccag gtccgtcacc accggcatgg tggtgatccg
    12121 gccgggccgg gccccggccg ggatcggcag cggcatcgac gggatgcggt tctggtcgta
    12181 gccgtcgtag aggaccaggt cggcgccgtc gaaatcacgg gcggtcaggt gcccgcggga
    12241 ggcccacggg tgtccggcgg gcaccacggc catcatctcg tcgtcgaaca gcttggtcag
    12301 ggacacccgg tccatctgca ggtccggctt ggtgaccagc gcgacgtcga ccaggtcggc
    12361 cagcagcgcc gggatcgggg cgtcgtcggc gacggcctcg atgcgcacgt cgatgtccgg
    12421 ctcgcgctcg cggaaagccc gcaggacggg cggcagccac gggaaggtgg tgctgcactg
    12481 cgcggtgaag cggacccgcc ggccgtgccc gtcgcggatc tcccgcaggt cacgggaggc
    12541 cgactccagt tcgccgagga tctggcgggc ggcgaccagc agccggcggc ccgccgcgtt
    12601 gggcaccagg cggcggccct tgcggtcgaa gagctgcatg ccgaggcggg cctcgagccg
    12661 ggtgagccgc tggctgaggg ccggctggct cacgtacagc cgctcggcgg cggccgtcag
    12721 cgagccggcc tcggccgtgg cgtcgaggag ctccaggtca cgcaggtcca catccataac
    12781 ctgggattat cacacgctcc aatctacgtc gtggtgttat gggttgaggg ttcataggtt
    12841 cttgggtgtc agccggacga acgagtccgc cgatccgccc cgaaag
//
