LOCUS       NZ_CP102509            26711 bp    DNA     linear   CON 06-JAN-2024
DEFINITION  Streptomyces sp. NBC_00162 chromosome, complete genome.
ACCESSION   NZ_CP102509
VERSION     NZ_CP102509.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. NBC_00162
  ORGANISM  Streptomyces sp. NBC_00162
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8635149)
  AUTHORS   Nielsen,J.B., Gren,T., Mohite,O.S., Joergensen,T.S., Klitgaard,A.,
            Mourched,A.-S., Blin,K., Larsen,T.O., Weber,T., Gotfredsen,C.H. and
            Charusanti,P.
  TITLE     Identification of the biosynthetic gene cluster for pyracrimycin A
            and elucidation of a key reaction during its biosynthesis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8635149)
  AUTHORS   Joergensen,T.S., Gren,T., Blin,K. and Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2022) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 05-AUG-2022
            Assembly Method :: Flye v. 2.9-b1768; Polypolish v. 0.5.0; POLCA
            polisher from MaSuRCA v. 4.0.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 40.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina Nextseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/05/2024 18:03:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,275
            CDSs (total)                      :: 8,175
            Genes (coding)                    :: 7,805
            CDSs (with protein)               :: 7,805
            Genes (RNA)                       :: 100
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 371
            CDSs (without protein)            :: 370
            Pseudo Genes (ambiguous residues) :: 0 of 371
            Pseudo Genes (frameshifted)       :: 186 of 371
            Pseudo Genes (incomplete)         :: 231 of 371
            Pseudo Genes (internal stop)      :: 27 of 371
            Pseudo Genes (multiple problems)  :: 68 of 371
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:41:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1884843
            Orig. end                         :: 1911554
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102509.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Tilmann Weber, Dr.
            Professor, Novo Nordisk Foundation Center for Biosustainability,
            Kemitorvet, 220, 327D 2800 Kgs. Lyngby, Denmark.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26711
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="14"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26711
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26711
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16711](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16711)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(167..2026)
                     /locus_tag="JIW86_RS09410"
                     /old_locus_tag="JIW86_09410"
     CDS             complement(167..2026)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006601993.1"
                     /locus_tag="JIW86_RS09410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09410"
                     /product="ATP-binding protein"
                     /protein_id="WP_257553347.1"
                     /transl_table=11
                     /translation="MSGLRAARHAPSRHAVTGPGRQTRPQLVRAAVLPTLAAGLSGTAA
                     VIFTLQLGGGAGDRDARLWPVLTGCALLFVAALAAALLGAQRAAKAVRDRCEALRRSSV
                     RGRQELRGAADRLERGEAPPRPVRGGPTGPPAGADPAGVDEFWLLSQELRGAREQAHET
                     LVRLAGPATPSDSERKVEVFVNLARRLQSLVHREISLLDELEDTVEDPDLLKELFHVDH
                     LATRIRRHAENLAVLGGAASRRQWTRPIDLSEVLRSSVAEVEQYTRVKVVPPAGGSVRG
                     HAVADVVHLLAELVENATVFSAPDTDVVLRAERVTAGIAVEVEDRGLGMPAEEQRRMNA
                     LLGDPDQISVRDLLADGRIGLFVVSALARRHGIAVELKSNIYGGVLAVLVLPQELLGAE
                     GPSAADAAGGSRATSWGTGQAAPMPMPMPMPMPPVPPPPLEPVRVNLPRPEPAEPLPED
                     WPGAAPGAVPRPAGPGHWPASGPGPEAVAGPGPGPGQRPAGAAVPLPGPRAGDGATASA
                     AALPERWAEPAPGPEPAAAAPAGTGTRAGAAAGAEAQPVPSEPEAADRPQLPRRRAQQH
                     LAPQLREAPAPRRAPDTEQPVHDPGLMAAFQRGFGLAQSENQV"
     misc_feature    complement(2196..2211)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.05"
                     /tool="antismash"
     gene            complement(2309..3508)
                     /locus_tag="JIW86_RS09415"
                     /old_locus_tag="JIW86_09415"
     CDS             complement(2309..3508)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267612.1"
                     /locus_tag="JIW86_RS09415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09415"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_257553348.1"
                     /transl_table=11
                     /translation="MTGSRPLRPRLRALRPEAFGADPSGARLERIHRSPNFADGVFKNP
                     LGARTRPSGSMTEFAKIYFHREQRVRRTPGAPIPVYPTTLAELAKPPASGLRLTWMGHS
                     SVLAEIDGRRVLFDPVWGERCSPFPFAGPKRLHPVPVPLASLGPVDVVVISHDHYDHLD
                     LPTIKELAGTDTLFAVPLGVGAHLERWGVPADRLRELDWNETTKIAGLTLTATPARHFC
                     GRGLRNQQHTLWASWVVAGDEHRIYHSGDTGYFPGFKEIGAEHGPFDATMIQIGAYSEY
                     WPDIHMTPEEGLRAHLDLQGGTPHGTMLPIHWGTFNLAPHPWDEPGEGTVTAAEGVGAA
                     IALPIPGQPFEPGAAGLPDQPWWRPFVVGGHAAPEVSVAAVAAARATGVIREEPEAVGS
                     "
     gene            complement(3640..4425)
                     /locus_tag="JIW86_RS09420"
                     /old_locus_tag="JIW86_09420"
     CDS             complement(3640..4425)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742770.1"
                     /locus_tag="JIW86_RS09420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09420"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_215144456.1"
                     /transl_table=11
                     /translation="MAATTTTLKTIGSYAAIGDSFTEGVGDPGPGDSYLGWADRLAVLL
                     ADRRDEHDFRYANLAVRGRLLDQIVAEQVPRAKELAPDLVTFCAGGNDIIRPGSDPDDV
                     AERFEAAVADLTGAVGLVMITTGFDTRGVPVLKHLRGKVATYSAHVRAIADRYDCPVLD
                     LWSLKSVQDRRAWDTDRLHLSPEGHTRVALRAAQVLGLEVPADPDQPWPPQRPRGSVDV
                     TRDNIQWAREHLVPWIGRRLRGESSGDHVEAKRPDLLPL"
     misc_feature    complement(4410..4430)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(4598..5569)
                     /locus_tag="JIW86_RS09425"
                     /old_locus_tag="JIW86_09425"
     CDS             complement(4598..5569)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964841.1"
                     /locus_tag="JIW86_RS09425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09425"
                     /product="LysM peptidoglycan-binding domain-containing M23
                     family metallopeptidase"
                     /protein_id="WP_257553349.1"
                     /transl_table=11
                     /translation="MPAKGKHRRPKSRSLSRGLAVAGTGGAALALPLMGAAGASAAVAP
                     AAAPATAPAVAPQLPLSLQAAPAAAVQAAPAVYTVVPGDYLSKIAAERHLSGGWEKLYA
                     DNREAVGTNPSLIHPGLKLTLGAKAEAPAEAAPAPAPAPAERSSTGSSASDEGSSGEQD
                     APAPVQQPKQKPQSSGSATGAKAPSAAGFVAPVSGGISTQYKVAGAMWSSGYHTGVDFI
                     ASSGTTVKAVGAGTVVSSGWAGAYGNEVIIKHADGHYSQYGHLSSLSVSVGQSVTAGQS
                     IGLSGSTGNSTGPHLHFEIRTTQSYGSDISPVNYLRSKGVTI"
     misc_feature    5568..5586
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.44"
                     /tool="antismash"
     regulatory      complement(5574..5771)
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    5762..5776
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.69"
                     /tool="antismash"
     misc_feature    complement(5957..5970)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     gene            6064..6855
                     /locus_tag="JIW86_RS09430"
                     /old_locus_tag="JIW86_09430"
     CDS             6064..6855
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="JIW86_RS09430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09430"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_257553350.1"
                     /transl_table=11
                     /translation="MTQRIQEPELSGVRNFRDVGGLPTFDGRQVRSGRLFRSGHLAHAT
                     ETDAEFLASLGLHTIFDFRNNADHALEGPDVELPGVRNVNIPLSDPADGREFWKMVRDG
                     GLDQLRSILGEGKAAARMSNAYRAIIRHRTAEHSRVLHALAEDSVPALLHCAAGKDRAG
                     LSIAVVLLALGVEREAIVADYLESNAPHRRYRVRRSGESQEARSPEVMELLAPLFDARA
                     EYLTTAFDTIDEQWGGQERYLAEGLGLTPETLDRLRGRLLA"
     gene            complement(6890..8305)
                     /locus_tag="JIW86_RS09435"
                     /old_locus_tag="JIW86_09435"
     CDS             complement(6890..8305)
                     /NRPS_PKS="Domain: Aminotran_3 (51-373). E-value: 8e-86.
                     Score: 280.0. Matches aSDomain:
                     nrpspksdomains_JIW86_RS09435_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955415.1"
                     /locus_tag="JIW86_RS09435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09435"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_257553352.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.4e-84, bitscore:
                     282.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEPREEGGRGKGFDLGALLAERGGERYELHSRHLNHQLPRMLH
                     TIGFDKVYERAEGAHFWDAEGNDYLDMLAGFGVMGLGRHHPVVRRALHDVLDAQLADLT
                     RFDCQPLPGLLAEKLLSYSPHLDRVFFGNSGTEAVETALKFARYATGRPRILYCDHAFH
                     GLTTGSLSVNGEGGFRDGFAPLLPDTKITLGDLGALERELRKGDVAAFVVEPVQGKGVL
                     SAPPGFLLAAQELLRRHKALLIADEVQTGLGRTGDFYAYQHEPGVEPDLVCVAKALSGG
                     YVPVGATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMEDEGVVANARA
                     MGDLLRGRLAALVDEYELLHEVRGRGLMIGIEFGRPSSLGLRSRWTMLQAARKGLFAQM
                     VVVPLLQKHRILTQVSGDHLEVIKLIPPLIVDERDVDRFVGAFREVMDEAHGGSGLMWE
                     FGRTLVKQAVGNR"
     aSDomain        complement(7187..8152)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JIW86_RS09435_Aminotran_3.1"
                     /evalue="8.00E-86"
                     /label="JIW86_RS09435_Aminotran_3.1"
                     /locus_tag="JIW86_RS09435"
                     /protein_end="373"
                     /protein_start="51"
                     /score="280.0"
                     /tool="antismash"
                     /translation="VYERAEGAHFWDAEGNDYLDMLAGFGVMGLGRHHPVVRRALHDVL
                     DAQLADLTRFDCQPLPGLLAEKLLSYSPHLDRVFFGNSGTEAVETALKFARYATGRPRI
                     LYCDHAFHGLTTGSLSVNGEGGFRDGFAPLLPDTKITLGDLGALERELRKGDVAAFVVE
                     PVQGKGVLSAPPGFLLAAQELLRRHKALLIADEVQTGLGRTGDFYAYQHEPGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMEDE
                     GVVANARAMGDLLRGRLAALVDEYELLHEVRGRGLMIGIEF"
     gene            complement(8302..9333)
                     /gene="hpnH"
                     /locus_tag="JIW86_RS09440"
                     /old_locus_tag="JIW86_09440"
     CDS             complement(8302..9333)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742776.1"
                     /locus_tag="JIW86_RS09440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09440"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_257553353.1"
                     /sec_met_domain="PF04055 (E-value: 2.2e-17, bitscore: 62.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.6e-08, bitscore: 32.0,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQTIRVGTYLLEQKLRKREKFPLIVELEPLYACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKRKYVF
                     LCTNAMLLRKKIEKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVAAIKEAKKRGF
                     RVTTNSTFFNTDTPQTIIEVLNYLNDDLQVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FRKAFAGGNRRRWRLNHSPLFLDFLEGKADFACTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIDDTDWSKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARETIGGNRD
                     SSA"
     gene            complement(9339..10001)
                     /locus_tag="JIW86_RS09445"
                     /old_locus_tag="JIW86_09445"
     CDS             complement(9339..10001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330384.1"
                     /locus_tag="JIW86_RS09445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09445"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_257553354.1"
                     /transl_table=11
                     /translation="MSALRGDRAGNPDPLLVACALRIEQTALRSAGRGDYALLRTGMGP
                     RAAERSVARALERTGMERAAVLATGFCAGLVPGMHPGDLVVADQTRDPHGAVTCTGTAL
                     LAEALARAVPGRTVHTGALTGSDHVVRGQERAQLRATGAIAVDMESAATLWAATRGDRC
                     PSEGGRPVAAVRVIVDAPEHELVRIGTVRGGISAFRVLRAVLPAFYDWHRSLLLPRR"
     gene            complement(10001..12040)
                     /gene="shc"
                     /locus_tag="JIW86_RS09450"
                     /old_locus_tag="JIW86_09450"
     CDS             complement(10001..12040)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994386.1"
                     /locus_tag="JIW86_RS09450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09450"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_257553355.1"
                     /sec_met_domain="T2TS (E-value: 1.8e-149, bitscore: 497.7,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSAESAGAGSRIEAGPGPGPDPAVPPPSAERGTAARTAP
                     PDGHRGDAYEAAARATRHLLARQDPEGWWKGDLETNVTMDAEDLLLRQFLGIRDEATTR
                     AAALFIRGEQRDDGTWATFHGGPPELSATIEAYVALRLAGDEPDAPHMARASAWIRAHG
                     GIAAARVFTRIWLALFGWWDWDHLPELPPELVFLPPWVPLNIYDFGCWARQTIVPLTIV
                     SALRPVRPAPFALDELHADARVPNPAKRLAPLASWDGAFQRMDKALHVYRRFAPRRLRK
                     AAMAAGARWIVERQENDGCWGGIQPPAVYSVIALHLLGYDLGHPVMRAGLESLDRFAVW
                     REDGARMIEACQSPVWDTCLAAIALADAGLRPDHPALVKAADWMLGEEIARSGDWAVRR
                     PGLAPGGWAFEFHNDTYPDIDDTAEVVLALRRVKHPDPARVEAAIARGVSWNLGMQSKN
                     GAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEMLAFEGKAGDARTRRGIAW
                     LLAEQEPDGAWFGRWGTNYVYGTGSVVPALTAAGIAPAHPAIRRAVRWLESVQNEDGGW
                     GEDQRSYKDRSWAGKGASTPSQTAWALMALLSAGERDGKAVERGIAHLVATQAEDGSWD
                     EPHFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPFAAAGGS"
     gene            complement(12168..13322)
                     /locus_tag="JIW86_RS09455"
                     /old_locus_tag="JIW86_09455"
     CDS             complement(12168..13322)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386166.1"
                     /locus_tag="JIW86_RS09455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09455"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_257553356.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.4e-57, bitscore:
                     193.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTSTTSTARTGTRGEPVNPGNPAVENTDASVGAAGGGVEKADT
                     LALLDRGRTLSTPALRAVVDRLAAPMDTVAAYHFGWIDAQGNPADGDGGKAVRPALALL
                     SAEAAGAAAEVGIPGAVAVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPALAILVGD
                     ALFALAYEVLLELGTVEAARAARRLTTASRGLIDGQAQDISYEHRERVSVEECLEMEGN
                     KTGALLACAVSIGAVLGGADDRTADKLEEYGYHLGLAFQAVDDLLGIWGDPESTGKQTW
                     SDLRQRKKSLPVVAALAADGPASEELAQLLAADAKSNDFENFSEEEFAARAALIEAAGG
                     RQWTADEARRQHAVAIKALDDVDMPQRVRDQLVALADFVVVRKR"
     gene            complement(13319..14698)
                     /gene="hpnE"
                     /locus_tag="JIW86_RS09460"
                     /old_locus_tag="JIW86_09460"
     CDS             complement(13319..14698)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848333.1"
                     /locus_tag="JIW86_RS09460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09460"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_257553357.1"
                     /sec_met_domain="DAO (E-value: 3.2e-08, bitscore: 32.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGSDQHAVVVGGGLAGVTTALELADAGLRVTLLEGRPRLGGLAF
                     SFKRGELTVDNGQHVYLRCCTAYRWFLDRVDGAALAPLQDRLDVPVLDVAHPKGPRLGR
                     LRRSALPVPLHLAGSLARYPHLSLAERASVGRAALALRRLDPADPALDGLDFATWLGRY
                     GQSPRTIEALWDLVGIATLNATAEHSSLGLAAMVFKTGLLSENGAADIGWARVPLGDLH
                     DALARKALDAAGVRTELRTRVTAISRTAEGNWRVDTENESLDAATVVLAVPQREAHGLL
                     PAGALADPDKLLDIGTAPILNVHVVYDRQVLKRPFFAALGSPVQWVFDRTDSSGLPDGG
                     QYLALSQSVAQDDIDEPVSVLRAKYLPELERLLPAARGAKVRDFFVTRERTATFAPTPG
                     VGRLRPGARTDTPGLYLAGAWTATGWPATMESAVRSGLSAAHAALAALGRPREHPLQEA
                     A"
     gene            complement(14835..15785)
                     /gene="hpnD"
                     /locus_tag="JIW86_RS09465"
                     /old_locus_tag="JIW86_09465"
     CDS             complement(14835..15785)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139892.1"
                     /locus_tag="JIW86_RS09465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09465"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_257553358.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.5e-56, bitscore:
                     190.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 7e-70,
                     bitscore: 234.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPTVEGPTHVSAPVQAAYGYCEAVTGSQARNFAYGIRLLPTDKR
                     QAMSALYAFSRRVDDIGDGTLAPEAKLARLEETRALLGRIRAEEIDEDDTDPVAVALAH
                     AARRFPIPLGGLDELIDGVLMDVRGETYETWDDLKAYCRCVAGAIGRLSLGVFGTAPGV
                     PDSGRAAEYADTLGLALQLTNILRDVREDAANGRTYLPAEDLAKFGCSEGFQGDRAPEG
                     SDFAGLVHHEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIEREPEAVLR
                     GRVSLPPHEKAYVAVRGLSGLDARTISRQSTRRRT"
     gene            complement(15782..16711)
                     /gene="hpnC"
                     /locus_tag="JIW86_RS09470"
                     /old_locus_tag="JIW86_09470"
     CDS             complement(15782..16711)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742782.1"
                     /locus_tag="JIW86_RS09470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09470"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_257553359.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.7e-35, bitscore:
                     120.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.9e-36,
                     bitscore: 124.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAGDGIRPLSDTVHARATLGKAATENFPVAPAFLPRAWRDGLMA
                     VYGYARLVDDIGDGDLAPGGRDAVLLGLEPAAVDDPLAMLDAFEADLWRVFGGTDGPPR
                     HPLMQALQPVVRAHQLTPEPFLGLIEANRQDQRVARYETYGDLLGYCELSANPVGRLVL
                     SLTGTATPERIRRSDAVCTALQIAEHLQDVTEDLGRDRIYLPAEDMRRFHVAETDLKAP
                     SAGASVRALIAYETERARELLNEGTPLVGSVHGRLRLLLAGFVGGGRAALRAVTAAGFD
                     VLPGPPKPTKSGLIREVAAVLRTAPRKG"
     misc_feature    16668..16681
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    16669..16683
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.0"
                     /tool="antismash"
     gene            complement(17085..17867)
                     /locus_tag="JIW86_RS09475"
                     /old_locus_tag="JIW86_09475"
     CDS             complement(17085..17867)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742783.1"
                     /locus_tag="JIW86_RS09475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09475"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_257553360.1"
                     /transl_table=11
                     /translation="MADSTQGRVPTVIADGVHIVYRVNTGSAGKGAATAALSKMVRRKK
                     GDAPGVRRVHAVRGVSFTAYRGEAIGLIGSNGSGKSTLLRAIAGLLPCEEGKVYTDGQP
                     SLLGVNAALMNDLTGERNIVLGGLAMGMSREQIKERYQGIVDFSGINEKGDFISLPMRT
                     YSSGMAARLRFSIAAAKDHDVLMIDEALATGDRSFQVRSENRIRELREKAGTVFLVSHN
                     NKSIRDTCDRVLWLEKGELLMDGPTEEVVSAYEKASNG"
     gene            complement(17860..18789)
                     /locus_tag="JIW86_RS09480"
                     /old_locus_tag="JIW86_09480"
     CDS             complement(17860..18789)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964854.1"
                     /locus_tag="JIW86_RS09480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09480"
                     /product="ABC transporter permease"
                     /protein_id="WP_257553361.1"
                     /transl_table=11
                     /translation="MSDTTHDGALATSRPPSEDAGLSSAELARKYGLSVSGARPGLGEY
                     VRQLWGRRHFVMAFSRAKLVAQYSQAKLGQVWQVATPLLNAAVYWLIFGVILGAGREMP
                     KDVYIPFLVIGIFVFTFTQSSVMAGVRAISGNLGLVRALHFPRAALPVSFSLQQLQQLL
                     YSMIVVFVIAICFGNYPRLAWLLVIPTLALQFVFNTGLAMIFARMGSKTPDLAQLMPFV
                     MRTWMYASGVMFPIGIYLDDQPEWISDLLLWNPVAIYMDLMRFALVDDYGSSNLPPHVW
                     LFAVGWAAVIGLGGFVYFWKAEERYGRG"
     gene            complement(18883..19755)
                     /locus_tag="JIW86_RS09485"
                     /old_locus_tag="JIW86_09485"
     CDS             complement(18883..19755)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="JIW86_RS09485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09485"
                     /product="glycosyltransferase"
                     /protein_id="WP_257559271.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.2e-10,
                     bitscore: 39.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLGAVIITMGNRPDELKALLDSVARQDGDPVEVVVVGQGVRLSG
                     LPEGVRTVELPENLGIPGGRNVGIEAFGPGGSEVDALLFLDDDGLLERTDTAELCRQAF
                     AEDPGLGIVSFRIADPETGETQRRHVPRLRASDPMRSSRVTTFLGGANAVRTRVFEQVG
                     PLPGDFFYAHEETDLAWRALDAGWLIDYRADMVLLHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPAPLVPVYLGVWLLLTLLRRPSVPALKAWFGGFREGWTTPCGPRRPMRWRTVWRL
                     TRLGRPPVI"
     gene            complement(19764..20543)
                     /locus_tag="JIW86_RS09490"
                     /old_locus_tag="JIW86_09490"
     CDS             complement(19764..20543)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="JIW86_RS09490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09490"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_257553362.1"
                     /transl_table=11
                     /translation="MPRPSVAELRPVVHPAGVKDRVSGEHWGGRLYMREISLRITRHLV
                     TTKVTPNQLTYVMTLAGVLALPALLVPGIWGAVLGVVMVQLYLLLDCVDGEVARWKKQF
                     SLSGVYLDRVGAYLCDAAVLVGFGLRASDLWGGGPVDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQAGKPVVKDAAAEPRSSGMALARRAAAALKFHRLVLGIEASLLILVLAVADQ
                     VRGDLFYSRIGVAVLAGIAMLQTVLHLVSILASSRLK"
     gene            complement(20521..21582)
                     /locus_tag="JIW86_RS09495"
                     /old_locus_tag="JIW86_09495"
     CDS             complement(20521..21582)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452391.1"
                     /locus_tag="JIW86_RS09495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09495"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_215144436.1"
                     /sec_met_domain="Fe-ADH (E-value: 2.1e-19, bitscore: 68.4,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.8e-08, bitscore:
                     32.7, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIASGAMDDLAGLLADQRISASGKLAIAISG
                     GSGVALRAKLEPVLPHADWYAVVDGTIDSAVKLADDIKGRRYDAVVGLGGGKIIDVAKY
                     AAARVGLPMVAVATNLSHDGICSPVSILDNDNGRGSYGVPTPIAMVIDLDVIKEAPVRF
                     IRAGIGDAISNISAIADWELSHKVTGEPVDGLAAAMARTAGESVLRHPGGCGDDEFLTV
                     LSEALVLSGIAMSISGDSRPSSGACHEISHAFDLLYPGRSALHGEQVGIGAAFAMHLRG
                     ADEKSGLFIEVLRRHGLPVTPEEIGFSIDEFVTAVEYAPQTRPGRFTILEHLNLSAAEI
                     RDAYADYAKTIRS"
     gene            complement(21570..22322)
                     /locus_tag="JIW86_RS09500"
                     /old_locus_tag="JIW86_09500"
     CDS             complement(21570..22322)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="JIW86_RS09500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09500"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_215144434.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.7e-09, bitscore:
                     37.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVGPAGDEESITVLDLTLG
                     NFAEVGLTEVAIVVGYRKEAVYERREALEAKYGVKITLIDNDKAEEWNNAYSLWCARDV
                     LKQGVILANGDTVHPVSVEKTLLAARGNGQKIILALDTVKSLADEEMKVVTADGQGVRK
                     ITKLMDPADATGEYIGVTLIEAEAAEQLADALKTTFERDPDLYYEDGYQQLVNDGFTID
                     VAPIGDVKWVEIDNHDDLAKGRTIACQY"
     gene            complement(22319..23926)
                     /locus_tag="JIW86_RS09505"
                     /old_locus_tag="JIW86_09505"
     CDS             complement(22319..23926)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962486.1"
                     /locus_tag="JIW86_RS09505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09505"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_257553363.1"
                     /transl_table=11
                     /translation="MHALRLALTDPRFDACAVTGALAVQPGAREALDKAAAAPGDGPDP
                     YADRLAAAVEAAGTAVQRPELGTLVAAVPATSADRDAAVAAVAAVDDEAVRLRTAVKSR
                     DGFFTTFCISPYSRYIARWCARRGLTPNQVTTASLITALIAAGCAATGERWGYVAAGVL
                     LLFSFVLDCTDGQLARYSLQYSTMGAWLDATFDRAKEYAFYAGLALGAARNGDDVWALA
                     LGAMILMTCRHVVDFSFNEANHDATANTSPTAALSDRLDSVGWTVWVRRMIILPIGERW
                     AMIAVLTAFTTPRIVFYALLIGCAFGALYTTAGRVLRSLTRKATRTDRAAQALYDLTDS
                     GPLAEFPRRLLGARGPAASSVWIAAFGAVALIGFALSRPYGDPALIAVAVLYAVAAGEA
                     VSRPLKGALDWLIPPLFRAAEYVTVLVLAAKADVPGALPAAFGLIAAVAYHHYDTVYRI
                     RGGTGAPPHWLVRTIGGHEGRVLLTTVLAAVLATRATDFPVALTAMAVFVALVVLVESI
                     RFWVSSGAPAVHDEGEPA"
     misc_feature    24264..24278
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            24533..>25375
                     /locus_tag="JIW86_RS09510"
                     /old_locus_tag="JIW86_09510"
                     /pseudo=""
     CDS             24533..>25375
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848345.1"
                     /locus_tag="JIW86_RS09510"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="JIW86_09510"
                     /product="class I SAM-dependent methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEAFFTLHRGLPRQAPGSDASTRHLLSLCGPLPERPRVLDLGCGP
                     GRSALLLAAEAGGHGAEVTAVDLYAPFLEELRTAAGARGLGDRVRTVRADMGALPGGEG
                     EDFADGSFDLVWAEGSAYVIGFDTALARWRRLLAPGGTLVLTECQWTVAEPSAGARAFW
                     DKECPLRSTAGNLAAAQAAGYRVLGVHHLPDSDWAEYYGPLAERVRTHPGAGDPATAAA
                     LAATREELRVRARHGHEYGYTGYVLRPVTAGDGGA"
     misc_feature    24534..24549
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.24"
                     /tool="antismash"
     gene            25550..26149
                     /gene="idi"
                     /locus_tag="JIW86_RS09515"
                     /old_locus_tag="JIW86_09515"
     CDS             25550..26149
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766530.1"
                     /locus_tag="JIW86_RS09515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_09515"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_215144461.1"
                     /transl_table=11
                     /translation="MPTTPATAANSATNGTGAQEPIMLELVDESGNTIGTAEKLSAHQA
                     PGQLHRAFSVFLFDEQGRLLLQQRALGKYHSPGVWSNTCCGHPYPGESPFAAAARRTHE
                     ELGLSPSLLAEAGTVRYNHPDPASGLVEQEFNHLFVGLAQATVRPDPEEVGDTAFVTAE
                     ELAKRHAAVPFSAWFMTVLDAARPAIRELTGDAAGW"
ORIGIN
        1 caggtcacca ggccgtcggc ggtgagcagc acggcgctgc gcgtgtacgg gacgcgttgc
       61 accaggccgc tgagcagcca gtccaggtcc gagagccgac cgccggtcgt cgtcgccact
      121 tcgccgccca tgggggtgcg ctccttgctg aggtgagggg tcggggtcat acctggttct
      181 ccgactgggc gaggccgaag ccccgttgga aggcggccat caggcccggg tcgtgtacgg
      241 gttgctcggt gtccggggcc cgccgcggag cgggagcctc gcgcagctgg ggcgcgaggt
      301 gctgctgggc ccggcggcgc ggcagctgcg gccggtccgc ggcctcgggt tcggacggca
      361 cgggctgggc ttcggccccg gctgcggccc cggcccgagt gccggtcccg gccggggctg
      421 cggctgcggg ctcaggcccg ggcgccggct cggcccaccg ctccggcagg gccgccgctg
      481 aagccgtggc cccgtccccg gctcggggcc cgggcagcgg cacggccgcg cctgcgggcc
      541 gctgcccggg cccggggccg ggccctgcga cggcttcagg cccaggcccg gacgcgggcc
      601 agtgaccggg cccggccggc ctggggacag cccccggggc ggccccgggc cagtcctccg
      661 gcaggggctc ggccggttcc ggccgcggca ggttcacccg tacgggctcc agcggcggcg
      721 gtggcaccgg cggcatcggc atcggcatcg gcatcggcat cggcgccgcc tgcccggtcc
      781 cccacgaggt ggcgcgggag ccccccgccg catcggcggc gctcggcccc tccgcgccca
      841 gcagctcctg cggcagcacc agcacggcga gcaccccgcc gtagatgttg gacttgagct
      901 cgacggcgat cccgtgccga cgggccagcg ccgagacgac gaacagcccg atccgcccgt
      961 ccgccagcag atcccggacg ctgatctggt cggggtcgcc gagcagggcg ttcatccggc
     1021 gctgttcctc cgccggcatg cccagccccc ggtcctccac ctccaccgcg atcccggcgg
     1081 tgacccgttc ggcgcgcagc accacgtcgg tgtcgggggc ggagaacacc gtggcgttct
     1141 cgaccagttc ggccagcagg tgcaccacgt cggcgacggc gtggccgcgt acgctgccgc
     1201 ccgccggggg cacgaccttg acccgggtgt actgctcgac ctccgcgacc gaggagcgga
     1261 gcacctcgct caggtcgatg ggccgggtcc actggcgccg ggaggcggcg ccgccgagca
     1321 cggcgaggtt ctcggcgtgg cggcggatgc gggtggcgag gtggtctacg tggaagagct
     1381 ccttgagcag gtccgggtcc tcgaccgtgt cctccagctc gtccagcagc gagatctcgc
     1441 ggtggacgag ggactgcagg cggcgcgcga ggttgacgaa gacctcgacc ttccgctcgc
     1501 tgtcggacgg ggtggccggg ccggccagcc gtacgagggt ctcgtgggcc tgttcgcggg
     1561 cgccgcgcag ctcctgggag agcagccaga actcgtccac ccccgccggg tcggcgccgg
     1621 ccgggggccc ggttgggccg ccgcgcaccg ggcggggcgg ggcctcgccg cgctcgagcc
     1681 ggtctgcggc gccgcgcagc tcctggcggc cgcgcacgct ggaacggcgc agcgcctcgc
     1741 accggtcccg tacggccttg gcggcgcgct gggcgccgag cagggcagcg gcgagggctg
     1801 cgacgaagag gagggcgcag ccggtgagca caggccagag ccgggcgtcc cggtccccgg
     1861 ctcccccgcc gagctggagg gtgaagatga ccgcggcggt gccgctgagc ccggcggcga
     1921 gcgtgggcag tacggcggcc cggaccagct gggggcgtgt ctgccggccg ggaccggtga
     1981 cggcgtgtct cgacggggcg tggcgggcgg cgcggagtcc ggacatcggc gtcctcggta
     2041 cgtggggccc ggcccccagc gatcccgggg cccggtgttg atcaccgaat acccacgcta
     2101 gaccgcaccg tcccgccccg gacgtccagt tggggaagtt cgcgggggtg cttcccgctc
     2161 ccggtggagc gctcgtacag ccgcccgaat cccccgggtc gcctccggcg tgatcccaac
     2221 ctggatccgg catgatcccg gcgtgggtcc gccgtggatc cggcggccgg aaccccgcgg
     2281 acctccgccg ccaccgagcc gccggggctc aggaaccgac ggcttccggc tcctcgcgga
     2341 tcacgcccgt cgcccgggcc gcggcgaccg cggcgacgga cacctccggt gcggcgtggc
     2401 cgcccaccac gaacggccgc caccacggct ggtccggaag accggcggcg cccggctcga
     2461 agggctggcc cgggatcggc agggcgatcg cggctccgac cccctccgcc gcggtgacgg
     2521 ttccctcgcc cggctcgtcc cacgggtggg gggccaggtt gaaggtgccc cagtggatcg
     2581 gcagcatcgt gccgtgcggg gtgccgccct ggaggtcgag gtgggcgcgc aagccctcct
     2641 cgggcgtcat gtggatgtcg ggccagtact cggagtaggc gccgatctgg atcatcgtgg
     2701 cgtcgaaggg cccgtgctcg gcgccgatct ccttgaaacc ggggaagtag ccggtgtccc
     2761 cgctgtggta gatccggtgc tcgtcccccg cgacgaccca ggaggcccac agggtgtgct
     2821 gctggttgcg cagcccgcgt ccgcagaagt gccgggcggg ggtcgcggtg agcgtgagcc
     2881 cggcgatctt ggtggtctcg ttccagtcca gctcgcgcag ccggtcggcc gggacgcccc
     2941 agcgctccag gtgcgcgccg actcccagcg ggaccgcgaa gagcgtgtcc gtaccggcca
     3001 gctccttgat cgtcggcagg tcgaggtggt cgtagtggtc gtgcgagatg accacgacgt
     3061 cgaccgggcc cagcgaggca agcggcacgg gcacggggtg cagccgcttg ggcccggcga
     3121 agggaaaggg cgagcaccgc tcgccccaca cggggtcgaa cagcacgcgt cgcccgtcga
     3181 tctccgcgag cacgctggag tgccccatcc aggtgagccg cagtccgctc gcgggcggct
     3241 tcgccagctc cgcgagggtc gtcgggtaca cggggatcgg cgccccgggg gtgcgccgga
     3301 cccgctgctc ccggtggaag tagatcttgg cgaactcggt catcgacccc gagggcctgg
     3361 tccgggcccc gagcgggttc ttgaagacgc cgtcggcgaa gttcggcgag cggtggatcc
     3421 gctccagccg ggcgccggac gggtccgcgc cgaaggcttc gggccgcagg gcacgcagcc
     3481 ggggacgcag gggacgggag ccggtcaagg cgcctcctgg gaggatgggg gtcgggacgg
     3541 tcgtcggtct acgaccatcc caacgcacac atacccccaa ggattccgct tacggccctc
     3601 gtttcccgtc tgcggcgctc cccccgcccg tcgctcccct tacaggggca gcaggtccgg
     3661 ccgcttcgcc tcgacgtggt ccccggagga ctcgccgcgc agccgccgcc cgatccaggg
     3721 caccaggtgc tcgcgcgccc actggatgtt gtcccgggtc acgtccaccg agccgcgcgg
     3781 ccgctgcggc ggccacggct ggtcggggtc ggcgggcacc tccagtccga gcacctgcgc
     3841 ggcgcgcagc gccacccgcg tgtgcccctc gggcgagagg tgcagccggt cggtgtccca
     3901 ggcccgccgg tcctgtacgg acttcagcga ccagaggtcg agcaccgggc agtcgtagcg
     3961 gtcggcgatg gcgcgcacgt gcgcgctgta cgtcgccacc ttgccccgga ggtgcttgag
     4021 gaccggcaca ccccgggtgt cgaagccggt ggtgatcatg accaggccga cggccccggt
     4081 gaggtcggcg acggcggcct cgaaccgctc cgccacgtcg tcggggtcgc tgccgggccg
     4141 gatgatgtcg ttgccgcccg cgcagaaggt cacgaggtcc ggggcgagct ccttggcccg
     4201 cgggacctgc tcggccacga tctggtcgag gagccggccg cgcacggcca ggttcgcgta
     4261 tcggaagtcg tgctcgtcgc gccggtcggc caggagcacg gcgagccggt ccgcccagcc
     4321 gagataagaa tccccgggtc ccgggtcccc cacgccctcg gtgaagctgt ccccgatcgc
     4381 cgcgtacgag ccgatggtct tgagtgtcgt cgtcgtcgct gccacgaaac gacatccttc
     4441 acccgagcac acgacctacg ccaacgtaag caggggttga cggaccgtga tctataccac
     4501 ccgggggata aggaataagt acacatcagg ccgggacccc cctcgggccc cggcctgaca
     4561 tgtgttcgtg ctccggcggc ggctgccgtc ggttgcgtca gatggtgacg cccttcgagc
     4621 ggaggtagtt caccgggctg atgtccgagc cgtaggactg ggtcgtacgg atctcgaagt
     4681 ggaggtgcgg gccggtcgag ttgccggtgg agccggagag accgatgctc tggccggcgg
     4741 tgacgctctg gcccaccgag acggacagcg aggagaggtg gccgtactgg gagtagtggc
     4801 cgtcagcgtg cttgatgatg acctcgttgc cgtacgcgcc ggcccagccg gacgagacca
     4861 cggtgcccgc gccgacggcc ttgacggtgg tgccggagct ggcgatgaag tcgacgccgg
     4921 tgtggtaacc cgaggaccac atcgcgcccg cgaccttgta ctgggtggat atcccaccgc
     4981 tcaccggggc cacgaatccg gcggcgctgg gggccttcgc cccggtggcc gagccgctgc
     5041 tctgcggctt ctgcttcggc tgctggacgg gggcgggcgc gtcctgctcg cccgaggagc
     5101 cctcgtcgga ggccgaagaa ccggtcgagg accgctcggc gggggccgga gccggggccg
     5161 gggctgcctc ggccggagcc tcggccttcg cgccgagggt cagcttcaga cccgggtgga
     5221 tcagggaggg gttggtgccg acggcctcgc ggttgtcggc gtacagcttc tcccagccgc
     5281 ccgagaggtg ccgctccgcg gcgatcttgg agaggtagtc gccgggcacg accgtgtaga
     5341 cggccggcgc ggcctgcacg gcggcggcgg gcgcggcctg gagcgagagc ggaagctgcg
     5401 gggcgacggc gggggccgtg gccggcgcgg cggccggcgc gacggccgcg ctggcgccgg
     5461 cggcacccat caggggcagc gcgagggccg caccaccggt gccggcaacg gcgagaccgc
     5521 gggaaaggga acgggacttg ggacgacggt gcttaccctt tgcaggcatg gcgaattcct
     5581 ctccgtcgcc ggcgaggtga gctgtcgggt tcggactgga gatgtccgga cgtacatgta
     5641 cggaacatga acgacttcac ccctagccgt cccggaagaa agatccggaa cagcggctta
     5701 cctggttccc ccgctcctgc cgcgcgcgtg aatagtcggg tgcggtttcc gggaggcggc
     5761 aggattaggc ggtccacccg gatcggtcgc gaacgtaatc gaatccgggc acagggaaca
     5821 agccatgaat ttcccaaagg aatcaccggg atgaggaatc ggcggaattc cggtcaccct
     5881 ctgtccattc cccaccgtca acaaccgccc cggccgggcc attcgccctt cgcgatcagg
     5941 cactcacggt caccgtatga tctggctcac gggggcacgt ccgatctcgc cgccggatat
     6001 ggcaagttgg cgccaagtgg ctcaattcgg acagacgccc cacgacgaag cggaggagtt
     6061 cctttgaccc agcggataca ggagccggaa ctgtccggag tgcgcaattt ccgcgatgtg
     6121 ggcggattgc cgactttcga cggacgacag gtcaggtcgg gacgactgtt tcgaagcgga
     6181 catctcgcac atgccaccga aaccgatgca gagttcctcg catcgctcgg gctccacacc
     6241 atcttcgact tccgcaacaa cgccgaccac gccctggagg ggccggacgt cgagctgccc
     6301 ggcgtgcgga acgtcaacat cccgctctcg gacccggccg acggccggga gttctggaag
     6361 atggtccgcg acggcggcct cgatcagctc cgctcgatcc tgggggaagg caaggccgcg
     6421 gcccggatgt cgaacgcgta ccgcgcgatc atcaggcacc gcaccgccga gcacagcagg
     6481 gtgctgcacg ccctcgccga ggacagcgtc cccgctctgc tgcactgcgc ggccggcaag
     6541 gaccgggcgg gcctgtcgat cgcggtcgtc ctgctcgcgc tgggcgtcga acgcgaggcg
     6601 atcgtggcgg actacctgga gtcgaacgcc ccgcaccgcc gctaccgggt gcggcgcagc
     6661 ggcgagtcgc aggaggcccg ctcccccgag gtgatggagc tcctcgcccc gctcttcgac
     6721 gcgcgcgcgg agtacctgac cacggccttc gacaccatcg acgagcagtg gggcggacag
     6781 gagcggtacc tcgcggaggg cctcgggctc acgcccgaga ccctcgaccg gctccggggc
     6841 cggctcctcg cctgacaccc gctcgttcca cccctgccgg agcaggtcgt caacggttgc
     6901 cgacggcctg cttcaccagg gtcctgccga actcccacat cagccccgag ccgccgtgcg
     6961 cctcgtccat gacctcgcgg aaggcgccga cgaaccggtc gacgtcccgc tcgtccacga
     7021 tcagcggcgg gatgagcttg atcacctcca ggtggtcccc ggacacctgg gtgaggatcc
     7081 ggtgcttctg cagcagcggc accacgacca tctgcgcgaa gagccccttg cgagccgcct
     7141 ggagcatggt ccaccggctg cgcagcccca gcgaggacgg ccggccgaac tcgatgccga
     7201 tcatcagccc gcgcccgcgc acctcgtgca gcagctcgta ctcgtccacc agggccgcga
     7261 gccgcccgcg cagcagatcg cccatggccc gggcgttggc gacgaccccc tcgtcctcca
     7321 tgaccgacag caccgccagt ccggccgcca tcgcctgggc gttggagccg aagctcgcgg
     7381 agtgcacgag gacccggtcc atggacgagt agaccttctt gaagatccag tccttgccca
     7441 gggtcgctcc gaccggcacg tagccgcccg agagcgcctt ggccacgcac accaggtccg
     7501 gctccacgcc cggctcgtgc tggtaggcgt agaagtcccc ggtccgtccg aggccggtct
     7561 gcacctcgtc cgcgatcagc agcgccttgt ggcggcgcag cagttcctgc gccgcgagca
     7621 ggaacccggg cggggcggag agcacgccct tgccctggac cggctccacg acgaaggcgg
     7681 ccacgtcgcc cttccggagc tcccgctcca gggcgcccag atccccgagg gtgatcttcg
     7741 tgtcgggcag cagcggcgcg aaaccgtccc ggaagccgcc ctccccgttc accgagagcg
     7801 accccgtcgt gagcccgtgg aaggcgtggt cgcagtagag gatcctgggc cgtccggtgg
     7861 cgtaccgggc gaacttcagg gccgtctcca ccgcctcggt gccgctgttg ccgaagaaga
     7921 cccggtccag gtgcgggctg tacgagagga gcttctcggc cagcagcccg ggcagcggct
     7981 ggcagtcgaa gcgggtgagg tcggctagct gggcgtccaa gacgtcgtgc agggcccggc
     8041 ggaccaccgg atggtgccgg cccaggccca tcaccccgaa cccggccagc atgtcgaggt
     8101 agtcgttgcc ctcggcgtcc cagaaatggg cgccctcggc ccgctcgtag accttgtcga
     8161 agccgatggt gtgcagcatc cggggcagtt ggtggttgag gtgcctggag tgcagctcgt
     8221 accgctcgcc accgcgctcg gccagcaggg cgccgaggtc gaagcccttg ccccggccgc
     8281 cctcctcccg tggctccgcg gtcatgccga gctgtcccgg ttcccgccga tcgtctcccg
     8341 ggccgcccgc agcgactcct tgagggagcc catggtggcg aggacggcgg tgggctcgta
     8401 gccgcagtgc gccatgcagt tcgcgcagcg cggatccttg ccgcggccgt acttgctcca
     8461 gtcggtgtcg tcgatgagtt cccggtacgt cggcacgtag ccgtcgctca tcagatagca
     8521 gggacgctgc cagccgaaga gggagtaatt cggaatggcc caggccgtgc aggcgaaatc
     8581 ggcctttcct tccaggaagt ccaggaagag cggcgagtga ttgagccgcc agcgcctgcg
     8641 gttgccgccc gcgaaggcct tcctgaagag ttcgcgggtc tgttcgacgc ccaggaagtg
     8701 ctcctggtcg ggggcctttt cgtaggcgta ggcgggcgag atcatcatct cgtccacctg
     8761 gaggtcgtca ttgaggtagt tgagcacctc gatgatcgtc tggggggtgt ccgtgttgaa
     8821 gaaggtggag ttggtggtca cccggaaccc gcgcttcttc gcctccttga tggccgcgac
     8881 ggcctcgtcg aagacgcctt ccttggccac cgactcgtcg tgccgttcgc gcagtccgtc
     8941 gatgtgcacg gcgaaggcga aataggggga cggggtgaac ttctcgatct tcttgcgcag
     9001 gagcatcgcg ttggtgcaga ggaatacata cttccgcttc gccaccaact gacggacgat
     9061 ctcgtcgatc tgcgggtgca tcaagggctc tccacccgcg atggacacca tgggcgcgcc
     9121 ggactccagc acggcgccga ccgcctgggc gaccggcatg cgctgcttga gcaccccggc
     9181 cgggtgctgg atcttcccgc acccctcaca ggccaggttg caggcgtaga gcggttccag
     9241 ctcgacgatc agcgggaact tctcacgctt gcggagcttc tgttcgagca aatacgtccc
     9301 gaccctgatg gtctggcgca gcggcatggc catctggctc acctcctggg gagcagcaaa
     9361 gaacggtgcc agtcataaaa cgcgggcagt acggcacgca gtacacggaa ggccgatatt
     9421 ccaccgcgga ccgtgccgat acggacgagc tcatgctccg gagcgtccac gatcacccgg
     9481 acggccgcaa ccgggcgtcc tccctccgag gggcagcggt cgccccgggt ggcggcccac
     9541 agggtggccg cggactccat gtcgaccgcg atggcgccgg tggcgcgcag ctgcgcacgc
     9601 tcctggccgc ggacgacgtg gtcggatccg gtcagtgcgc cggtgtgcac ggtccggccg
     9661 gggacggccc gggccagtgc ctcggcgagc agggcggtcc cggtacaggt gaccgccccg
     9721 tgcgggtccc gggtctggtc ggcgacgacc aggtcgccgg ggtgcatgcc ggggaccagg
     9781 ccggcgcaga atccggtggc gaggacggcg gcccgctcca tgcccgtccg ctccagcgcc
     9841 cgggcgacgg accgctcggc cgcgcgcggg cccatgccgg tccggagcag ggcgtagtcc
     9901 ccgcggccgg cgctgcgcag cgccgtctgt tcgatgcgca gcgcgcaggc caccagcagg
     9961 gggtctgggt tcccggccct gtccccccgg agggcggaca tcaggatccc ccggcggccg
    10021 cgaagggttc cccgtgcagg tagcgtccga gtgccgtgag cgggaacacc tgccggtaca
    10081 ggtggtagtt gatggagaag tcccagggga agccggtgcc cgtgaagtgg ggctcgtccc
    10141 aggaaccgtc ctcggcctgg gtcgccacca ggtgggcgat gccccgctcg acggccttgc
    10201 cgtcccgctc tcccgccgac agcagggcca tcagcgccca cgccgtctgc gagggggtgg
    10261 aggccccctt cccggcccat gaccggtcct tgtaggagcg ctggtcctcg ccccacccgc
    10321 cgtcctcgtt ctgtacggat tccagccagc gcacggcccg ccggatcgcg ggatgcgccg
    10381 gggcgatgcc ggccgcggtg agggccggga ccaccgaccc ggtgccgtag acgtagttgg
    10441 tgccccagcg gccgaaccag gctccgtcgg gctcctgttc ggcgagcagc caggcgatgc
    10501 cgcgccgggt ccgcgcgtca cccgccttgc cctcgaaggc gagcatctcc accacgtggg
    10561 cggtgacgtc ggccgagggc gggtcgatga cctcgccgaa gtcgcagaag ggcagccggt
    10621 tcgggaaggg gctggtgttg tcggcgtcga aggcgcccca cgcgccgttc ttcgactgca
    10681 tgcccaggtt ccaggacacc ccgcgggcga tggccgcctc gacccgggcc gggtcggggt
    10741 gcttgacgcg gcgcagcgcg agaacgacct cggcggtgtc gtcgatgtcg gggtaggtgt
    10801 cgttgtggaa ctcgaacgcc cagccgccgg gggcgagtcc gggccgccgt accgcccagt
    10861 ccccgctgcg cgcgatctcc tcgccgagca tccagtcggc tgccttgacc agcgccgggt
    10921 ggtcggggcg caggcccgcg tcggccaggg cgatcgcggc gaggcaggtg tcccagaccg
    10981 gggactggca tgcctcgatc atccgggcgc cgtcctcgcg ccacaccgcg aaccggtcga
    11041 gggattccag gccggcgcgc atcaccgggt gcccgaggtc gtatccgagc aggtgcaggg
    11101 cgatgaccga gtacacggcg ggtggctgga tgccgcccca gcagccgtcg ttctcctgcc
    11161 gttcgacgat ccatcgggcg ccggcggcca tggcggcctt gcgcagccgg cgcggggcga
    11221 accggcggta gacgtgcagg gccttgtcca tccgctggaa ggcgccgtcc caactggcca
    11281 gcggggcgag ccgtttggcg gggttcggca cccgcgcgtc ggcgtgcagc tcgtccaggg
    11341 cgaagggggc cgggcggacc gggcgcagcg cggagacgat cgtgaggggg acgatggtct
    11401 ggcgggccca gcagccgaag tcgtagatgt tcagcggcac ccagggcggc aggaacacca
    11461 gctcgggcgg gagttcggga aggtggtccc agtcccacca gccgaagagc gccagccaga
    11521 tgcgggtgaa gacgcgggcg gcggcgatcc cgccgtgggc ccggatccag gccgacgcgc
    11581 gggccatgtg cggggcgtcc ggctcgtctc cggcgaggcg cagggccacg tacgcctcga
    11641 tggtggcgga gagttcgggc ggcccgccgt ggaaggtggc ccaggtgccg tcgtcccgct
    11701 gctcgccgcg gatgaagagg gcggcggcgc gggtggtggc ctcgtcccgg atcccgagga
    11761 actgacgcag cagcaggtcc tcggcgtcca tggtgacgtt ggtctccagg tcgcccttcc
    11821 accacccctc ggggtcctgg cgcgcgagca ggtgcctggt cgcccgcgcg gcggcctcgt
    11881 acgcgtcccc ccggtggccg tccggcggtg cggtccgggc cgcggtgccc cgttccgcgc
    11941 tgggcggtgg caccgccggg tccgggcccg gtccgggccc ggcttcgatc ctgctgcccg
    12001 cgccagcgct ctccgcgctg ccgtcggtcg tcgctgtcat ggcttcccct tcgtgcagtc
    12061 tgtcctctgc tgtgctgggg tctgccgtcg gccagcgcgc tccccctcag tcgggggtgg
    12121 cggcgccggc cggcgactcg cgagtcatat ccgcttccgg gcggcgttca cctcttgcgg
    12181 acgacgacga agtcggcgag ggccaccagc tggtcgcgca cccgctgggg catgtcgacg
    12241 tcgtccagtg ccttgatcgc caccgcgtgc tggcggcgcg cctcgtcggc ggtccactgg
    12301 cgtccgccgg ccgcctcgat gagcgccgcg cgggccgcga actcctcctc cgagaagttc
    12361 tcgaagtcgt tgctcttggc gtcggcggcg agcagctggg cgagttcctc actggcgggc
    12421 ccgtcggccg cgagggcggc gaccaccggc agggacttct tgcgctggcg caggtcgctc
    12481 caggtctgct tgccggtgga ctccgggtcg ccccagatgc cgagcaggtc gtccacggcc
    12541 tggaaggcga ggccaaggtg gtagccgtac tcctcgagct tgtcggccgt acggtcgtcc
    12601 gcgccgccga ggaccgcgcc gatggagacc gcgcaggcga gcagggcgcc cgtcttgttg
    12661 ccctccatct ccaggcactc ctcgacgctg acgcgctcgc ggtgctcgta ggagatgtcc
    12721 tgggcctggc cgtcgatgag cccccggctg gcggtggtca ggcggcgggc cgcgcgggcc
    12781 gcctcgacgg tgccgagctc cagcagcacc tcgtaggcga gggcgaagag cgcgtcgccg
    12841 accaggatcg ccagggcggg gccgtgcacc ttccacaccg tgtcgcggtg gcggcgctgc
    12901 tcgtctccgt ccatcaggtc gtcgtgcagc agcgagaagt tgtgcacgag ctcgaccgcg
    12961 acggcgccgg ggatgccgac ctcggccgcg gcgcccgcgg cctcggcgga gagcagcgcg
    13021 agggcgggcc ggacggcctt gccgccgtcg ccgtccgcgg ggttgccctg ggcgtcgatc
    13081 cagccgaagt ggtaggcggc gacggtgtcc atgggcgcgg cgagccggtc cacgacggcg
    13141 cggagcgcgg gcgtcgacag cgtgcggccc cggtccagga gggcgagcgt gtcggccttc
    13201 tccactcccc cgccggctgc gcccacactg gcatccgtgt tctcgacagc cggattcccc
    13261 gggttcactg gctctcctct ggttcctgta cgggctgtgc tggtcgtgct ggtcgtcgtc
    13321 atgccgcctc ctgcagaggg tgttcgcggg ggcggccgag ggcggcgagt gcggcgtgcg
    13381 ccgcgctcag tccgctccgg acggcgctct ccatggtcgc gggccaaccg gtggcagtcc
    13441 acgcaccggc cagatacagc cccggcgtgt cggtccgcgc cccggggcgc agccggccga
    13501 cgccgggtgt gggggcgaag gtggccgtcc gctcccgggt gacgaagaag tcccgtacct
    13561 tggcgccgcg cgcggcgggc agcaaccgct ccagctcggg caggtacttg gcgcgcagga
    13621 cggacacggg ctcgtcgatg tcgtcctggg cgacggactg ggacagggcc aggtactggc
    13681 cgccgtcggg gagcccggag gagtcggtgc ggtcgaagac ccactgcacc ggggagccga
    13741 gcgccgcgaa gaagggccgc ttgagcacct ggcggtcgta cacgacgtgg acgttgagga
    13801 tcggcgcggt gccgatgtcg agcagcttgt cggggtcggc gagagctccg gccgggagca
    13861 gtccgtgcgc ctcgcgctgc gggacggcca ggacgacggt ggcggcgtcc agggactcgt
    13921 tctcggtgtc gacccgccag ttcccttcgg cggtacggga gatggcggtg acccgggtgc
    13981 gcagttcggt ccgtacgccg gccgcgtcga gcgccttgcg ggcgagcgcg tcgtgcaggt
    14041 cgccgagcgg tacgcgggcc cagccgatgt cggcggcgcc gttctcggag agcaggccgg
    14101 tcttgaagac catggcggcc aggccgaggg aggagtgctc ggcggtggcg ttgagggtcg
    14161 cgatgccgac gaggtcccac agggcctcga tggtccgggg ggactggccg tagcggccga
    14221 gccaggtggc gaagtccagg ccgtccagcg ccgggtcggc ggggtcgagg cggcgcagcg
    14281 cgagggcggc gcggccgacg ctcgcgcgtt cggcgaggga caggtgcggg tagcgggcca
    14341 gcgatccggc caggtgcagg ggcacgggca gggcgctgcg gcgcagccgg ccgaggcgcg
    14401 gtcccttggg gtgggcgacg tcgagtacgg gtacgtcgag ccggtcctgg aggggcgcga
    14461 gggcggcgcc gtcgacgcgg tcgaggaacc accggtaggc ggtgcagcag cgcaggtaga
    14521 cgtgctggcc gttgtccacg gtgagttcgc cgcgcttgaa cgagaacgcg agcccgccga
    14581 gccgcgggcg gccttcgagg agggtgaccc gcagtcccgc gtcggcgagt tcgagggcgg
    14641 tcgtaacgcc ggcgaggccg ccgccgacga cgacggcgtg ctggtcgctg ccggtcatga
    14701 gccctccccg gtgttggcgt gcccggccgg gcacgcggct gccgagccct ccgggagaga
    14761 cgcggccgcc cacgcggggg ttgcctgtcc cggagccgcg gcggtcgtcg tcatcgtcgt
    14821 cgtcctcgag ggcatcaggt ccgcctccgg gtgctctgcc gggagatggt ccgcgcgtcg
    14881 aggccggaga ggccgcgcac ggcgacgtac gccttctcgt gcggcggcag cgagacgcgg
    14941 ccgcgcagga ccgcctccgg ctcccgctcg atgcggtcga ggaggcgccg gtagatgccg
    15001 gccatggcgg ccacgcaggc gccgctgcgc cggtcgagca tcggcagcag ccggtagccc
    15061 tcggcgaaca gcgcccgggc gcgccgcact tcgtggtgca cgagcccggc gaagtcggaa
    15121 ccctcggggg cccggtcgcc ttggaagccc tcggagcagc cgaacttggc gaggtcctcg
    15181 gcgggcaggt aggtgcgccc gttggcggcg tcctcgcgaa cgtcccggag gatgttggtg
    15241 agttgcaggg ccaggccgag cgtgtcggcg tactcggcgg cgcgcccgga gtcggggact
    15301 cccggtgcgg tgccgaacac gccgagcgag agccgcccga tggccccggc cacgcagcgg
    15361 cagtaggcct tgaggtcgtc ccaggtctcg tacgtctcgc cgcgcacgtc catcaggacg
    15421 ccgtcgatga gttcgtcgag gccgccgagc gggatcggga accggcgcgc tgcgtgcgcg
    15481 agggcgacgg cgaccgggtc ggtgtcgtcc tcgtcgatct cctcggcgcg gatccgcccg
    15541 agcagggcgc gggtctcctc cagccgggcc agcttcgcct cgggcgccag cgtgccgtcg
    15601 ccgatgtcgt cgacccgccg ggagaaggcg tacagcgcgg acatcgcctg ccgcttgtcg
    15661 gtgggcagca gccggatgcc gtacgcgaag ttgcgcgcct gcgatccggt gacggcctcg
    15721 cagtagccgt acgccgcctg gaccggcgcg gacacgtgtg tggggccctc cacggtcggg
    15781 ctcacccctt tctcggcgca gtgcgcagga cggcggccac ctcgcggatc aagccgctct
    15841 tggtgggctt gggcgggccg ggaagtacgt cgaagccggc ggcggtgacg gctctcaggg
    15901 cggcccgccc ccctcccacg aagcccgcga gcagcagccg gagtctgccg tgcacgctac
    15961 ccacgagggg ggtgccttca ttcagcagct cccgcgcgcg ttcggtttcg tatgcgatca
    16021 gggcgcgtac ggacgcgccg gcggacgggg ccttgaggtc ggtctccgcc acgtggaagc
    16081 gccgcatgtc ctcggcgggc aggtagatcc ggtcccggcc gaggtcctcg gtgacgtcct
    16141 ggaggtgttc ggcgatctgc agggccgtgc agaccgcgtc ggagcggcgg atccgctcgg
    16201 gggtggcggt gccggtgagg gagagcacga ggcggcccac ggggttggcg gagagctcgc
    16261 agtagccgag gaggtccccg tacgtctcgt agcgcgcgac ccgctggtcc tggcggttgg
    16321 cctcgatgag cccgaggaac ggctcggggg tgagctggtg ggcgcgcacg acgggctgga
    16381 gggcctgcat cagcgggtgg cgcggcggac cgtcggtacc gccgaaaacg cgccacaggt
    16441 cggcctcgaa ggcgtcgagc atggcgagcg ggtcgtccac cgcggcgggt tcgaggccga
    16501 ggagcacggc gtcgcgtccg ccgggggcca ggtcgccgtc gccgatgtcg tcgacgaggc
    16561 gggcgtaccc gtagaccgcc atcaggccgt cccgccaggc gcggggcagg aacgcggggg
    16621 cgacggggaa gttctccgtc gcggccttgc cgagggtggc gcgcgcgtgg accgtgtcgg
    16681 acaggggccg gatgccgtcc cccgcggtca ccgcccgccg cctggggcgg ggacggccgt
    16741 caagcctggg ggccggagaa ttcccatagc cattgccgtc acgtctcccg ttctacactg
    16801 ctgacctaat acatcctatt tcggacacgc cgcccgggtt tccccggggt gcgccaggcc
    16861 gttcacctgc ggggaatcgt cccctcttgc cgcgattcag gactgcttca gcttacgctg
    16921 tacaacgcct tgaagacctc tggggtattc accgcgccac cgaatgtcgc cgccgaatgt
    16981 caccacccga tagcgccggg aattgccgcg acacgccgag gcccccgccg cgctgagcgg
    17041 cgggggcctc gcggggtccg gccgggggcg gccggctccc gtggtcagcc gttggacgcc
    17101 ttctcgtagg ccgagacgac ttcctccgtg ggcccgtcca tcaggagctc gcccttttcc
    17161 agccacagca cccggtcaca ggtgtcgcgg atggacttgt tgttgtggct caccaggaac
    17221 acggtgccgg ccttctcccg cagttcgcgg atgcggttct cggaacgcac ctggaaactg
    17281 cggtcaccgg tggccagggc ctcgtcgatc atcaggacgt cgtggtcctt ggccgccgcg
    17341 atggagaagc gcaggcgcgc cgccatgccg gaggagtagg tgcgcatcgg cagggagatg
    17401 aagtcgccct tctcgttgat tcccgagaag tcgacgatgc cctggtagcg ctccttgatc
    17461 tgctcgcggc tcatgcccat cgcgagaccg ccgaggacga tgttgcgctc gccggtcagg
    17521 tcgttcatca gcgccgcgtt cacgcccagc agcgagggct ggccgtcggt gtagaccttg
    17581 ccctcctcgc agggcaggag gcccgcgatg gcgcgcagca gggtcgactt gccggagccg
    17641 ttggagccga tgaggccgat ggcctcgccc cggtacgcgg tgaaggagac cccgcggacg
    17701 gcgtggaccc ggcggacgcc cggcgcatcg cccttcttcc ggcggaccat cttgctgagc
    17761 gcggcggtgg ccgctccctt gccggcgctg ccggtattga cgcggtagac gatgtggacg
    17821 ccgtccgcga tcacggtggg gacacgcccc tgggtactgt cagccacggc cgtaacgctc
    17881 ctcagccttc cagaagtaaa cgaatccgcc gaggccgatc actgcggccc agcccacggc
    17941 gaacagccag acgtgcggag gcaggttgct gctgccgtag tcgtcgacca gcgcgaaccg
    18001 catgaggtcc atgtagatcg ccaccgggtt ccacagcagc aggtcactga tccactccgg
    18061 ctggtcgtcg aggtagatcc cgatcgggaa catgacaccg gaggcgtaca tccaggtgcg
    18121 catcacgaac ggcatcagct gcgccaggtc gggggtcttg gaacccatcc gcgcgaagat
    18181 catggcgagg ccggtgttga agacgaactg gagcgccagc gtcgggatca cgagcagcca
    18241 ggcgagccgc gggtagttgc cgaagcagat ggcgatcacg aagacgacga tcatcgagta
    18301 cagcagctgc tggagctgtt gcagcgagaa ggacaccggc agggcggcgc gcgggaagtg
    18361 cagcgcccgc accaggccga ggtttccgga gatcgcccgg acacccgcca tcaccgagct
    18421 ctgggtgaag gtgaagacga agatgccgat caccaggaac gggatgtaga cgtccttggg
    18481 catctcccgg cccgcgccga ggatcacgcc gaagatcagc cagtagacgg ccgcgttgag
    18541 caggggggtc gccacctgcc agacctggcc gagcttcgcc tggctgtact gggcgaccag
    18601 cttggcccgg gagaaggcca tgacgaagtg acgccggccc cagagctgcc gcacgtactc
    18661 gcccaggccg ggccgtgcgc cgctcacgga gaggccgtac ttcctggcga gctccgcgga
    18721 actcagcccc gcgtcttcgg acggcggcct gctcgtggcg agggcgccgt cgtgggttgt
    18781 gtcactcaca agttgaaact ttcgtcttca agatgcggca ggggggcatc aggctggtgg
    18841 cgcgaagccc gtgatcgcgc catgttccca gacgcgggct cgtcagatga caggaggtcg
    18901 gcccagtcgg gtcaaccgcc agaccgtacg ccatctcatg ggacgacggg gaccgcaggg
    18961 agtggtccac ccctccctga aaccgccgaa ccaggccttg agcgcgggta ccgacggcct
    19021 gcgcaggagc gtcagcagga gccagacgcc caggtagacc gggaccagcg gagcgggcag
    19081 gttgcggcgg gcgagccaca cccggttacg ggccaccata cggtggtaga ccgcgtgccg
    19141 ggagggggca gtggtcgggt gcagcagcac catgtccgct cggtagtcga tcagccaccc
    19201 ggcgtcgagc gcccgccagg ccaggtcggt ctcctcgtgc gcgtagaaga agtcccccgg
    19261 cagcggcccg acctgctcga acacccgcgt gcggacggcg ttcgcgccgc ccaggaaggt
    19321 ggtcacgcgg gaggagcgca tcgggtcgga ggcgcgcagc cgcggcacgt gccggcgctg
    19381 ggtctcaccg gtctccggat cggcgatccg gaagctgacg atcccgagcc ccgggtcctc
    19441 cgcgaaggcc tgccggcaca gctcggcggt gtcggtgcgc tccagcaggc cgtcgtcgtc
    19501 caggaacagc agggcgtcga cctcgctgcc accgggcccg aaggcctcga tgccgacgtt
    19561 gcgcccgccg gggatgccca ggttctcggg cagctcgacg gtacggacgc cttcggggag
    19621 gccgctgagc cgcacgccct gacccaccac gaccacctcg acggggtcgc cgtcctggcg
    19681 ggcgaccgag tcgaggagcg ccttgagctc gtcgggccgg ttgcccatgg tgatgatcac
    19741 ggcgcccagc cgcatcgggg ccgtcacttg agcctgctgg aggccaggat cgacaccagg
    19801 tgcagcacgg tctggagcat cgcgatgccg gcgaggacgg cgacaccgat ccgggagtag
    19861 aacaggtcgc cgcggacctg gtccgcgacg gccagcacca ggatgagcag ggaggcctcg
    19921 atgcccagga cgagccggtg gaacttcagc gcggcggcgg cccggcgggc gagcgccatg
    19981 ccggacgaac gcggctcggc cgccgcgtcc ttgaccaccg gcttgccggc ctggtggcgg
    20041 gcgacaccga ccaggtcggt ctcggccttg atcaggatcg cgccgagcgc cgccagggtg
    20101 cccaggaagg cccacagcca gtcgaccggg ccgccgcccc acaggtcgga ggcgcgcagg
    20161 ccgaagccga ccagcaccgc cgcgtcgcac aggtaggcgc cgacccggtc caggtacacg
    20221 ccagagagcg agaactgctt cttccagcgg gcgacctcgc cgtcgacgca gtcgagcagc
    20281 aggtacagct ggaccatgac gacgccgagg acggcacccc agatgcccgg caccagcagg
    20341 gcggggaggg cgagcacgcc ggcaagggtc atcacgtagg tcagctggtt cggcgtgacc
    20401 ttggtggtga ccaggtggcg ggtgatgcgc agggagatct cgcgcatgta gaggcgcccg
    20461 ccccagtgct cgccgctgac ccggtccttg acgcccgccg ggtgaacgac gggccggagt
    20521 tcagctacgg atggtcttgg catagtcggc gtaagcgtcc ctgatctcgg cggcggacag
    20581 gttgaggtgc tccaggatcg tgaagcgtcc cgggcgggtc tgcggggcgt actcgacggc
    20641 cgtgacgaac tcgtcgatgc tgaagccgat ctcctccggg gtcaccggca ggccgtgccg
    20701 gcgcagcacc tcgatgaaga ggccggactt ctcgtcggcc ccgcgcaggt gcatcgcgaa
    20761 ggcggcgccg atgccgacct gctcgccgtg gagcgcggag cgccccgggt agagcaggtc
    20821 gaaggcgtgg ctgatctcgt ggcaggcgcc ggacgacggg cgggagtccc cgctgatcga
    20881 catggcgatg ccggagagga ccagcgcctc ggagagcacg gtgaggaact cgtcgtcacc
    20941 gcatccgccg gggtggcgca gcacggactc tccggcggta cgggccatgg cggcggccag
    21001 gccgtcgacg ggctcgccgg tgaccttgtg cgagagctcc cagtcggcga tcgccgagat
    21061 gttggagatc gcgtcgccga tgccggcgcg gatgaaccgc accggggctt ccttgatcac
    21121 atcgaggtcg atcaccatgg cgatcggcgt gggcacgccg taggaaccgc ggccgttgtc
    21181 gttgtccagg atggacaccg gcgagcagat gccgtcgtgc gagaggttgg tggcgacggc
    21241 caccatgggc agcccgaccc gcgccgcggc gtacttcgcc acgtcgatga tcttgccacc
    21301 gcccaggccc acgacggcgt cgtagcggcg gccctttatg tcgtcggcca gcttgaccgc
    21361 ggagtcgatg gtgccgtcga cgacggcgta ccagtcggcg tgcggcagca cgggctcgag
    21421 cttggcgcgc agcgcgacgc cggagccccc gctgatcgcg atcgccagct tgccggacgc
    21481 ggagatccgc tggtcggcca gcaggccggc cagatcgtcc atcgctccgc tggcgatgtc
    21541 gacgacgacg ggcgagggga tgagcctcgt cagtactggc atgcgatcgt ccggcccttg
    21601 gcgaggtcgt cgtggttgtc gatctcgacc cacttgacgt cgccgatggg ggccacgtcg
    21661 atggtgaagc cgtcgttgac gagctgctgg tagccgtcct cgtagtagag gtcggggtcg
    21721 cgctcgaaag tggtcttcag tgcgtcggcc agctgctcgg cggcctcggc ctcgatgagg
    21781 gtgacgccga tgtactcgcc cgtcgcgtcg gccgggtcca tcagcttggt gatcttccgg
    21841 acgccctgac cgtcggcggt gacgaccttc atctcctcgt cggccaggct cttgaccgtg
    21901 tcgagggcga ggatgatctt ctgcccgttg ccgcgggcgg cgagcagggt cttctcgacg
    21961 gagaccgggt ggacggtgtc gccgttggcg aggatcacgc cctgcttgag gacgtcacgc
    22021 gcgcaccaca gggagtaggc gttgttccac tcctcggcct tgtcgttgtc gatcagcgtg
    22081 atcttgacgc cgtacttggc ctcgagggcc tcgcggcgct cgtagacggc ctccttgcgg
    22141 tagccgacga cgatggcgac ctcggtgagg ccgacctcgg cgaagttgcc cagggtcagg
    22201 tcgagaaccg tgatgctctc ctcgtcgccc gcgggaccga cgggcacgag ggccttgggc
    22261 agggtgtcgg tgtagggacg cagacggcgt ccggcaccgg cagcgagtac aaggccgatc
    22321 atgctggttc tccttcgtca tgtacggcgg gtgctccgga ggagacccag aagcggatgc
    22381 tctccacgag caccacgagt gccacgaaca cggccatggc cgtgagcgcg acggggaagt
    22441 ccgttgcgcg cgtcgcgagg acggcggcca gcaccgtggt cagcaggacc cggccctcgt
    22501 ggccgccgat cgtccgcacc agccagtgcg ggggcgcgcc ggtgccgcca cgaatgcggt
    22561 acaccgtgtc gtagtgatgg taggcgaccg ccgcgatcag gccgaatgcc gccggaaggg
    22621 ccccggggac gtccgccttg gcggcgagca cgaggaccgt gacgtactcg gcggcccgga
    22681 acagcggcgg gatcagccag tccagggcgc ccttgagggg gcgcgagacg gcctcgccgg
    22741 cggccacggc gtagagcacg gcgacggcga tcagcgccgg gtcgccgtac gggcggctca
    22801 gggcgaagcc gatgagggcg acggcgccga aggcggcgat ccacacggag ctcgcggccg
    22861 gcccccgggc ccccagcagg cggcgcggga actcggcgag cgggccggag tcggtgaggt
    22921 cgtacagggc ctgcgcggcc cggtcggtgc gggtcgcctt gcgggtcagg gagcgcagga
    22981 cccgaccggc cgtggtgtag agcgcgccga aggcgcagcc gatgagcagg gcgtagaaga
    23041 cgatccgggg ggtggtgaag gcggtcagca ccgcgatcat cgcccagcgc tcaccgatcg
    23101 gcaggatgat catccggcgg acccagaccg tccagcccac gctgtcgagc ctgtcggaca
    23161 gcgcggccgt ggggctcgtg tttgccgtcg cgtcgtggtt ggcctcgttg aaggagaagt
    23221 ccacgacgtg ccggcaggtc atgaggatca tcgcgccgag cgcgagcgcc cagacgtcat
    23281 cgccgttgcg ggcggccccg agcgcgaggc ccgcgtagaa ggcgtactcc ttggcgcggt
    23341 cgaaggtcgc gtcgagccag gcgcccatcg tcgagtactg gagcgagtag cgggccagct
    23401 gcccgtcggt gcagtccagg acgaaggaga agaggagcag cacgccggcc gcgacgtagc
    23461 cccagcgctc gccggtggcg gcgcagccgg ccgcgatcag cgcggtgatc agcgaggcgg
    23521 tggtgacctg gttcggggtc aggccgcggc gcgcgcacca gcgggcgatg tagcgcgagt
    23581 acgggctgat gcagaaggtg gtgaagaagc cgtcgcggga cttcacggcg gtccgcaggc
    23641 gcacggcctc gtcgtcgacg gcggcgactg cggcgacggc cgcgtcccgg tccgccgagg
    23701 tggccgggac ggcggcgacg agggtgccga gctcggggcg ctggacggcg gtcccggcgg
    23761 cctcgaccgc ggcggcgagc cggtcggcgt agggatccgg gccgtcgccc ggggcggcgg
    23821 cggccttgtc gagcgcctcg cgggcgccgg gctggacggc gagggctccg gtgacggcgc
    23881 aggcgtcgaa gcgcgggtcg gtcagcgcga ggcgcagcgc gtgcacgtgc ccgacgaagg
    23941 cgctgtccac gacggccacc cgctggtcgg cgggtacggc ggccagtgcg gcggcggcgt
    24001 cctggggacc ggcggcggag cggacctcga agccgagtga gcgcagctcg tcagcgagcg
    24061 gtgatccggg gaccggcagg ccggtgagga tgacggtcgg cagacgaact cactccttgt
    24121 aacgaagtcc ggactggctc cggacgggcg cctcattggg gcggcggcac gtcggcagag
    24181 gctatcggat gaatggaagc aggggttcac cacccgttta cgccctgata agccgaatat
    24241 ccccggcccc gggccggggc gtgatcatca ttgacgatca cggcgcggta ccacaaacgg
    24301 cgccgatgtt acggtggaca cgcccctgat cgtgtcgagt ggaaagaggt gggttgatga
    24361 ccgtcgtagt ggtcgcggcc atgcgcagcg aactccggtg catcccccat ttcttccggg
    24421 catccggccg ggcctgatca tccactgacg gtccccgtcg gccggagccc ccgttcaagg
    24481 gttcacgttg accgacacca ctgacaccac cggcaccacc gacaccgcct tcattgaggc
    24541 cttcttcact ctgcaccgcg gcctgccccg gcaggctccc ggttccgacg cgagcacccg
    24601 gcacctgctg tccctgtgcg gaccgctgcc cgagcggccg cgcgtcctcg acctgggctg
    24661 cggtccgggc cgcagtgccc tgctgctcgc cgcggaggcg ggcgggcacg gcgccgaggt
    24721 gaccgccgtc gacctctacg caccgttcct cgaggagctc cgtacggccg ccggggcccg
    24781 cgggctcggc gaccgggtcc gcaccgtcag ggcggacatg ggcgcactgc ccggcgggga
    24841 gggcgaggac ttcgccgacg gctccttcga tctcgtctgg gcggagggtt ccgcctatgt
    24901 catcggcttc gacaccgcgc tcgcgcggtg gaggcggctg ctcgcccccg gcggcaccct
    24961 cgtgctgacc gagtgccagt ggaccgtcgc ggagccgtcc gccggcgccc gcgccttctg
    25021 ggacaaggaa tgcccgctgc gctccaccgc cggcaacctc gcggccgccc aggccgccgg
    25081 gtaccgggtg ctcggcgtgc accacctgcc cgactcggac tgggccgagt actacggccc
    25141 gctcgccgag cgggtcagga cccaccccgg cgccggggat ccggcgacgg cggccgcgct
    25201 ggccgccacc cgcgaggagc tccgcgtacg ggcccggcac ggacacgagt acgggtacac
    25261 cggctacgtc ctgcgcccgg tgaccgccgg ggacggcggc gcctgacccg cccggccgga
    25321 gaccccggcc gacggggccg ccgtacgggc cgtcaacctg gcggccttcg ggaccccgct
    25381 ggatatccgg ccccgttcgg ggtctgacgc cgcgggcgga gtacgtgaag tgatctgccc
    25441 ctcgtcgctt atcacgcgac ggggggcaga catgcgcgga tctccgaagt gcggacaagc
    25501 ctcttttgta cggcagactg aaggccggag tccgaagcga aggatgggta tgccgaccac
    25561 accagccacc gccgcgaaca gcgcgaccaa cggcaccggc gctcaagagc cgatcatgct
    25621 cgaactggtc gacgagtccg gcaataccat cggcacggcg gagaaactct ccgctcatca
    25681 ggcacccggg cagttgcacc gggcgttctc cgtgttcctc ttcgacgagc agggccgtct
    25741 gctgctccag cagcgggccc tcgggaagta ccactccccc ggcgtctggt cgaacacctg
    25801 ctgcggtcac ccctaccccg gggagtcgcc gttcgcggcc gcggcccggc ggacccacga
    25861 ggagctgggg ctgtccccct cgctgctcgc ggaggcgggg acggtccgct acaaccaccc
    25921 ggaccccgcg tcgggtctgg tggagcagga gttcaaccac cttttcgtgg gactcgcgca
    25981 ggcgaccgtg cggccggatc cggaggaggt cggggacacc gccttcgtca ccgccgagga
    26041 gctggcgaag cggcacgccg cagtgccgtt ctctgcctgg ttcatgaccg ttctggacgc
    26101 ggcgcggccc gcgatccgcg agctgaccgg tgacgccgcg ggctggtagc ccttccccgg
    26161 ccagcgccgg gaggggtccc cgcaacggtc aggcgaccgg agccgcgggt gcggtcggcg
    26221 cggtgagcgg cagggccgcc cagatgacct tgccgcccgt cgaggtgtgc tcgacgtcgc
    26281 agaccccgcc ggcctccagc gtgacctccc gcaccaggag cagcccccgg ccgccggtct
    26341 ggccgaaatc ggcctccagt gccttggggc ggtacgggtg gttgtcctcg acggccaccc
    26401 gtacccactc gcggccgatc gcgacctcga cggcgacctc cggggagagc agggcggcgt
    26461 gccggaccga gttcgtcacc agttcggaga cgatcagcag cagggagtac acgaggtcct
    26521 gctgggcggg caccccctgg cgcccgagca ggtcccggac ggcgcggcgc gcctgcggaa
    26581 cggattcttc tactgcggga gcggtgaacc tccacactcc ctcgtacgcg agggggtcgg
    26641 cgggagcctc gggctccgcc tcccgggctg gcgggacgtt cccgctgaca tccatcttcc
    26701 gtcccccgtc t
//
